R/bootTEI.R
bootTEI.RdThis function computes the transcriptome evolutionary index (TEI) using permuted strata values.
bootTEI(
ExpressionSet,
Phylostratum = NULL,
permutations = 100,
split = 1e+05,
showprogress = TRUE,
threads = 1
)expression object with rownames as GeneID (dgCMatrix) or standard PhyloExpressionSet object.
a named vector representing phylostratum per GeneID with names as GeneID (not used if Expression is PhyloExpressionSet).
a numeric value specifying the number of permutations to be performed.
specify number of columns to split
boolean if progressbar should be shown
specify number of threads
a numeric matrix storing the TEI values based on permuted strata.
The strata values are sampled and the global TEI
is calculated N times.
Domazet-Loso T. and Tautz D. (2010). A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns. Nature (468): 815-818.
Quint M et al. (2012). A transcriptomic hourglass in plant embryogenesis. Nature (490): 98-101.
Drost HG et al. (2015) Mol Biol Evol. 32 (5): 1221-1231 doi:10.1093/molbev/msv012
## get Seurat object
celegans<-readRDS(file=system.file("extdata",
"celegans.embryo.SeuratData.rds",
package="scTEI")
)
## load Caenorhabditis elegans gene age estimation
celegans_ps<-readr::read_tsv(
file=system.file("extdata",
"Sun2021_Orthomap.tsv",
package="scTEI")
)
#> Rows: 20040 Columns: 2
#> ── Column specification ────────────────────────────────────────────────────────
#> Delimiter: "\t"
#> chr (1): GeneID
#> dbl (1): Phylostratum
#>
#> ℹ Use `spec()` to retrieve the full column specification for this data.
#> ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message.
## define Phylostratum
ps_vec<-setNames(
as.numeric(celegans_ps$Phylostratum),
celegans_ps$GeneID
)
## calculate TEI permutation values
bootTEI(
ExpressionSet=Seurat::GetAssayData(celegans, assay="RNA", layer="counts"),
Phylostratum=ps_vec
)
#> AAACCTGCAAGACGTG-300.1.1 AAACCTGGTGTGAATA-300.1.1
#> [1,] 4.380123 4.023529
#> [2,] 4.610656 4.351557
#> [3,] 4.256148 3.895502
#> [4,] 4.313525 4.080277
#> [5,] 4.260246 5.059516
#> [6,] 4.144467 4.123183
#> [7,] 4.257172 4.799308
#> [8,] 4.509221 4.695502
#> [9,] 4.454918 4.244983
#> [10,] 4.191598 4.188927
#> [11,] 4.616803 4.361246
#> [12,] 4.414959 3.869204
#> [13,] 4.605533 4.174394
#> [14,] 4.436475 4.615917
#> [15,] 4.077869 4.105190
#> [16,] 4.565574 4.328028
#> AAACCTGTCGGCCGAT-300.1.1 AAAGATGGTTCGTTGA-300.1.1
#> [1,] 4.505231 4.569509
#> [2,] 3.653538 3.987734
#> [3,] 3.846769 3.760514
#> [4,] 3.990769 4.032126
#> [5,] 5.173538 4.919393
#> [6,] 4.075077 3.951519
#> [7,] 4.843692 4.578855
#> [8,] 4.122462 4.580023
#> [9,] 4.323077 4.294977
#> [10,] 3.844923 3.656542
#> [11,] 3.949538 4.223715
#> [12,] 3.825231 3.995327
#> [13,] 4.275077 3.919977
#> [14,] 4.330462 4.416472
#> [15,] 3.631385 3.755257
#> [16,] 3.898462 4.062500
#> AACCATGAGAAACCTA-300.1.1 AACCATGAGTTGAGAT-300.1.1
#> [1,] 4.434685 4.568255
#> [2,] 3.995495 3.973748
#> [3,] 4.273649 4.240307
#> [4,] 4.409910 4.412359
#> [5,] 4.626126 4.920840
#> [6,] 4.207207 4.073506
#> [7,] 4.615991 4.345719
#> [8,] 4.216779 4.548061
#> [9,] 4.293919 4.186591
#> [10,] 4.102477 4.049273
#> [11,] 3.984234 4.050889
#> [12,] 4.370495 4.168013
#> [13,] 4.465653 4.357027
#> [14,] 4.203266 4.191438
#> [15,] 4.223536 4.137318
#> [16,] 4.197072 4.373183
#> AACGTTGAGTAAGTAC-300.1.1 AACTCAGTCTTATCTG-300.1.1
#> [1,] 4.665874 4.147990
#> [2,] 3.488109 4.125457
#> [3,] 4.004756 4.012789
#> [4,] 3.911415 4.050548
#> [5,] 4.942925 5.089525
#> [6,] 3.962545 4.004872
#> [7,] 4.847800 4.839220
#> [8,] 4.001784 4.601096
#> [9,] 4.257432 4.096224
#> [10,] 3.623662 4.046894
#> [11,] 4.161712 4.244823
#> [12,] 4.197384 4.026797
#> [13,] 4.044590 4.279537
#> [14,] 4.585612 4.456151
#> [15,] 3.712842 4.090134
#> [16,] 3.609394 3.864799
#> AACTCCCAGTGTACTC-300.1.1 AACTGGTAGGCAATTA-300.1.1
#> [1,] 4.789732 4.487525
#> [2,] 3.549107 3.898179
#> [3,] 3.851339 4.337829
#> [4,] 3.927232 4.262980
#> [5,] 5.546429 4.535401
#> [6,] 3.866964 3.995280
#> [7,] 4.945536 4.058665
#> [8,] 3.945536 4.755226
#> [9,] 3.857589 3.982468
#> [10,] 3.929018 3.833446
#> [11,] 3.941518 4.224545
#> [12,] 3.904464 4.121376
#> [13,] 4.234375 4.169926
#> [14,] 4.250893 4.146325
#> [15,] 3.969196 4.137559
#> [16,] 4.291518 4.583277
#> AACTTTCGTCTTCAAG-300.1.1 AAGCCGCTCAGAGACG-300.1.1
#> [1,] 4.998438 4.211745
#> [2,] 3.418750 3.942405
#> [3,] 3.782812 4.184641
#> [4,] 4.310938 4.541502
#> [5,] 5.535156 4.809712
#> [6,] 3.753906 3.893281
#> [7,] 4.989844 4.936759
#> [8,] 4.400000 4.257482
#> [9,] 4.053906 4.125353
#> [10,] 3.828125 4.090909
#> [11,] 3.837500 4.045172
#> [12,] 3.863281 4.452287
#> [13,] 3.946094 4.082439
#> [14,] 4.053125 4.113495
#> [15,] 4.278906 4.243930
#> [16,] 4.604688 4.540373
#> AAGGCAGGTGGGTATG-300.1.1 AAGTCTGTCCAAATGC-300.1.1
#> [1,] 4.663158 4.576343
#> [2,] 3.672022 4.161135
#> [3,] 3.936288 4.309596
#> [4,] 4.126870 4.380809
#> [5,] 5.492521 4.664454
#> [6,] 3.750693 4.048280
#> [7,] 5.144598 4.505733
#> [8,] 3.913019 4.495474
#> [9,] 3.737396 4.202776
#> [10,] 3.880332 4.284249
#> [11,] 4.024377 4.222692
#> [12,] 4.122992 4.101388
#> [13,] 4.448199 4.039831
#> [14,] 4.301939 4.375377
#> [15,] 3.669252 3.989137
#> [16,] 3.697507 4.003018
#> AAGTCTGTCTAACTCT-300.1.1 AATCGGTAGCGAGAAA-300.1.1
#> [1,] 4.487332 4.411574
#> [2,] 4.088674 3.602488
#> [3,] 4.458271 4.221741
#> [4,] 4.461252 4.591130
#> [5,] 4.577496 4.548405
#> [6,] 3.756334 3.731206
#> [7,] 4.446349 4.672255
#> [8,] 4.456781 4.371011
#> [9,] 4.331595 4.300162
#> [10,] 4.207899 3.923743
#> [11,] 4.114009 3.943213
#> [12,] 4.295827 4.023797
#> [13,] 4.587183 4.045430
#> [14,] 3.912817 4.029205
#> [15,] 4.447839 4.279611
#> [16,] 4.470939 4.448891
#> ACACCAAAGTTCCACA-300.1.1 ACACCCTCAAACGTGG-300.1.1
#> [1,] 4.895522 4.707419
#> [2,] 3.827784 3.224660
#> [3,] 3.921355 3.607106
#> [4,] 3.665901 4.153605
#> [5,] 4.773249 5.298851
#> [6,] 4.098737 3.874086
#> [7,] 4.106774 4.936259
#> [8,] 4.658439 4.042842
#> [9,] 4.419059 3.964995
#> [10,] 3.728473 3.530825
#> [11,] 4.369690 3.978579
#> [12,] 4.170494 3.777429
#> [13,] 4.482778 4.069488
#> [14,] 4.128588 4.506792
#> [15,] 3.982204 3.693312
#> [16,] 4.514925 4.136364
#> ACATGGTCAGTAGAGC-300.1.1 ACCAGTATCGTAGGTT-300.1.1
#> [1,] 4.575698 4.366097
#> [2,] 3.762289 4.305556
#> [3,] 3.999803 4.341168
#> [4,] 4.368069 4.002137
#> [5,] 5.023791 4.646011
#> [6,] 3.769367 4.197293
#> [7,] 4.861777 4.042023
#> [8,] 4.391663 4.650997
#> [9,] 4.102635 4.301282
#> [10,] 3.830319 4.124644
#> [11,] 4.054267 4.188746
#> [12,] 3.895203 4.188746
#> [13,] 4.166142 4.315527
#> [14,] 4.145497 4.108974
#> [15,] 3.888714 4.213675
#> [16,] 4.285883 4.611823
#> ACCTTTAAGATATGCA-300.1.1 ACGAGCCGTGAACCTT-300.1.1
#> [1,] 4.169811 4.749865
#> [2,] 4.246018 3.959569
#> [3,] 4.328596 4.022102
#> [4,] 4.212203 4.326685
#> [5,] 5.104631 5.171429
#> [6,] 4.244303 3.925067
#> [7,] 4.730213 4.827493
#> [8,] 4.300417 3.966577
#> [9,] 4.192355 4.215633
#> [10,] 4.129135 3.859299
#> [11,] 4.317324 3.867385
#> [12,] 4.185249 4.105660
#> [13,] 4.491546 4.360108
#> [14,] 4.505268 4.210782
#> [15,] 3.952708 3.710512
#> [16,] 4.255085 3.876011
#> ACGAGGACATCCTAGA-300.1.1 ACGATACTCGCGTAGC-300.1.1
#> [1,] 4.369375 4.772944
#> [2,] 4.107790 3.641740
#> [3,] 4.158496 4.123046
#> [4,] 4.282404 4.355540
#> [5,] 5.144728 5.032631
#> [6,] 4.195433 3.821210
#> [7,] 4.892881 4.299796
#> [8,] 4.293821 4.346023
#> [9,] 4.185695 4.178110
#> [10,] 4.137676 3.691366
#> [11,] 4.178643 4.083617
#> [12,] 4.115514 3.919782
#> [13,] 4.269644 4.288239
#> [14,] 4.294829 4.242012
#> [15,] 4.036602 3.959891
#> [16,] 4.297851 4.492862
#> ACGCAGCAGTGCGATG-300.1.1 ACGCAGCGTTCGCTAA-300.1.1
#> [1,] 4.522480 4.841707
#> [2,] 4.200272 3.963524
#> [3,] 4.200272 3.891948
#> [4,] 4.044278 4.157605
#> [5,] 4.496594 4.972471
#> [6,] 4.199591 3.873365
#> [7,] 4.163488 4.450791
#> [8,] 4.502725 3.935306
#> [9,] 4.388965 3.923606
#> [10,] 3.920300 3.738472
#> [11,] 4.149183 3.836201
#> [12,] 4.364441 3.809360
#> [13,] 4.226158 4.050241
#> [14,] 3.920981 4.260151
#> [15,] 4.204360 4.005506
#> [16,] 4.608311 4.387474
#> ACGCCAGGTTAAGGGC-300.1.1 ACGGAGAAGACACTAA-300.1.1
#> [1,] 4.216137 4.739130
#> [2,] 4.434040 4.216466
#> [3,] 4.527091 4.257169
#> [4,] 4.241461 4.553191
#> [5,] 4.439340 4.837188
#> [6,] 3.924617 4.103608
#> [7,] 4.514134 4.618871
#> [8,] 4.681390 4.192414
#> [9,] 4.291519 4.203515
#> [10,] 4.153710 4.167438
#> [11,] 4.142521 4.090657
#> [12,] 4.277385 3.990749
#> [13,] 4.415783 4.235893
#> [14,] 4.226148 4.146161
#> [15,] 4.277385 4.219241
#> [16,] 4.382214 4.475486
#> ACGGAGACAATAGCAA-300.1.1 ACGGAGACACACTGCG-300.1.1
#> [1,] 4.577266 4.605383
#> [2,] 3.849926 3.700720
#> [3,] 4.080238 4.070318
#> [4,] 3.910104 4.383055
#> [5,] 5.055721 5.054397
#> [6,] 3.846954 4.042835
#> [7,] 4.691679 4.646133
#> [8,] 4.202823 4.223086
#> [9,] 4.152303 3.979719
#> [10,] 3.801634 3.950341
#> [11,] 4.182764 4.167362
#> [12,] 4.091382 4.102729
#> [13,] 4.246657 4.226497
#> [14,] 4.391530 4.100455
#> [15,] 3.805349 4.025588
#> [16,] 4.538633 3.992229
#> ACGGGCTAGGAGTAGA-300.1.1 ACTATCTAGTGCAAGC-300.1.1
#> [1,] 4.257891 4.527510
#> [2,] 4.025404 3.642655
#> [3,] 4.143187 4.018718
#> [4,] 4.297921 4.412365
#> [5,] 4.959969 5.124220
#> [6,] 4.029253 3.747022
#> [7,] 4.486528 4.872944
#> [8,] 4.241724 4.070335
#> [9,] 4.220169 4.102099
#> [10,] 4.013087 3.945547
#> [11,] 4.393380 3.878049
#> [12,] 4.030793 4.107204
#> [13,] 3.996921 4.173001
#> [14,] 4.400308 4.340896
#> [15,] 3.842956 4.043676
#> [16,] 4.220169 3.981282
#> ACTATCTCAAACGTGG-300.1.1 ACTGCTCTCTTACCTA-300.1.1
#> [1,] 4.445347 4.463433
#> [2,] 4.361152 4.947761
#> [3,] 4.202363 4.176119
#> [4,] 4.285081 3.897761
#> [5,] 4.340473 4.447015
#> [6,] 4.221566 3.661940
#> [7,] 4.487445 3.751493
#> [8,] 4.754801 5.286567
#> [9,] 4.552437 4.114179
#> [10,] 4.327179 3.986567
#> [11,] 4.367061 4.635821
#> [12,] 4.692024 4.185075
#> [13,] 4.304284 4.570149
#> [14,] 4.132201 4.708209
#> [15,] 4.211965 3.585821
#> [16,] 4.392910 4.237313
#> ACTTACTGTGTAACGG-300.1.1 ACTTGTTTCAGGTAAA-300.1.1
#> [1,] 4.923650 4.379583
#> [2,] 3.331471 4.274112
#> [3,] 3.783054 4.009024
#> [4,] 3.975791 4.233503
#> [5,] 5.503724 5.074450
#> [6,] 3.714153 4.076142
#> [7,] 4.887337 4.988720
#> [8,] 4.065177 4.450649
#> [9,] 3.906890 3.921038
#> [10,] 3.796089 3.756909
#> [11,] 4.184358 4.386351
#> [12,] 3.988827 4.021997
#> [13,] 4.189944 4.219402
#> [14,] 4.465549 4.280880
#> [15,] 4.059590 3.813875
#> [16,] 4.516760 4.323181
#> ACTTTCACAAGTTGTC-300.1.1 AGACGTTAGGCCCGTT-300.1.1
#> [1,] 4.670594 4.434698
#> [2,] 3.838627 3.988068
#> [3,] 4.095799 4.215414
#> [4,] 4.429816 4.396646
#> [5,] 4.726434 5.173815
#> [6,] 4.099898 4.049984
#> [7,] 4.838115 4.704611
#> [8,] 4.684939 4.400516
#> [9,] 4.540471 4.081264
#> [10,] 3.931865 3.931957
#> [11,] 4.206967 4.188326
#> [12,] 3.938012 4.174137
#> [13,] 4.379098 4.313447
#> [14,] 4.246414 4.339890
#> [15,] 3.830943 4.195098
#> [16,] 4.135246 4.155756
#> AGAGCTTAGCGTGAAC-300.1.1 AGAGCTTCATGGAATA-300.1.1
#> [1,] 4.366921 4.218874
#> [2,] 4.302293 4.036067
#> [3,] 4.171647 3.952075
#> [4,] 4.134121 4.139822
#> [5,] 4.630994 5.189723
#> [6,] 4.206393 4.140316
#> [7,] 4.094510 4.999012
#> [8,] 4.415566 4.274209
#> [9,] 4.232106 4.063735
#> [10,] 4.005559 3.920455
#> [11,] 3.922863 4.355731
#> [12,] 4.175122 3.924901
#> [13,] 4.498263 4.156126
#> [14,] 3.908270 4.416502
#> [15,] 4.137596 3.725296
#> [16,] 4.596247 4.047925
#> AGAGTGGGTGGCAAAC-300.1.1 AGCAGCCTCATAACCG-300.1.1
#> [1,] 4.171310 4.530625
#> [2,] 4.047063 4.142511
#> [3,] 4.272214 4.187993
#> [4,] 4.251883 4.171013
#> [5,] 5.001506 4.408126
#> [6,] 4.103163 4.110976
#> [7,] 4.825301 3.996361
#> [8,] 4.296687 4.469982
#> [9,] 4.041039 4.199515
#> [10,] 4.322289 3.845361
#> [11,] 4.473268 3.938144
#> [12,] 4.042922 4.271680
#> [13,] 4.024473 4.388720
#> [14,] 4.493599 3.941783
#> [15,] 4.118599 4.247423
#> [16,] 4.150226 4.471195
#> AGCGTATAGTCGTTTG-300.1.1 AGCGTATTCGTCTGAA-300.1.1
#> [1,] 5.031599 4.325342
#> [2,] 3.398389 3.807791
#> [3,] 3.865551 3.829195
#> [4,] 4.069393 4.395976
#> [5,] 5.506815 5.335188
#> [6,] 3.586121 4.005993
#> [7,] 5.161710 5.171233
#> [8,] 4.134449 3.961473
#> [9,] 4.082404 4.020976
#> [10,] 3.656753 3.874144
#> [11,] 4.080545 4.029966
#> [12,] 4.008055 3.839897
#> [13,] 4.140025 4.355308
#> [14,] 4.425031 4.455908
#> [15,] 3.962825 3.883134
#> [16,] 4.291202 4.095462
#> AGCTCTCGTACTTCTT-300.1.1 AGGCCACCAGGTGGAT-300.1.1
#> [1,] 4.398053 4.090029
#> [2,] 3.662520 4.430784
#> [3,] 4.040022 4.258470
#> [4,] 4.050297 4.162633
#> [5,] 4.967009 4.729913
#> [6,] 4.037858 4.302033
#> [7,] 4.909681 4.335915
#> [8,] 4.310438 4.344627
#> [9,] 4.151433 4.197483
#> [10,] 3.955652 4.448209
#> [11,] 4.107085 4.222652
#> [12,] 4.102758 4.241045
#> [13,] 4.379124 4.197483
#> [14,] 4.326122 4.033882
#> [15,] 4.230936 3.930300
#> [16,] 4.264467 4.468538
#> AGGCCGTCACTAGTAC-300.1.1 AGGGAGTCACCTATCC-300.1.1
#> [1,] 4.523242 4.420631
#> [2,] 3.680572 3.570818
#> [3,] 3.886770 4.020844
#> [4,] 4.409416 4.140567
#> [5,] 4.738379 4.733832
#> [6,] 4.055423 3.912881
#> [7,] 4.687723 5.167825
#> [8,] 4.119785 4.258685
#> [9,] 4.184148 4.185462
#> [10,] 3.911800 3.928915
#> [11,] 3.901073 4.142170
#> [12,] 3.947557 3.885623
#> [13,] 4.275924 4.288616
#> [14,] 4.233611 4.183859
#> [15,] 3.803337 3.647247
#> [16,] 4.344458 4.010689
#> AGGGAGTTCTGATTCT-300.1.1 AGGGATGAGCCGCCTA-300.1.1
#> [1,] 4.713568 4.564387
#> [2,] 3.514796 3.643869
#> [3,] 4.084869 3.692545
#> [4,] 4.243439 4.205176
#> [5,] 4.828029 5.397412
#> [6,] 4.155221 3.507086
#> [7,] 4.910664 4.746149
#> [8,] 4.223897 4.354898
#> [9,] 4.093802 3.809612
#> [10,] 3.788945 3.465804
#> [11,] 4.311558 4.051140
#> [12,] 4.166946 3.874923
#> [13,] 4.282524 4.076402
#> [14,] 4.132887 4.179914
#> [15,] 3.719710 3.913740
#> [16,] 3.745952 4.495995
#> AGGGATGGTCCGTCAG-300.1.1 AGGGTGAAGCGTGAGT-300.1.1
#> [1,] 4.792525 4.793325
#> [2,] 3.977117 3.603338
#> [3,] 4.383677 4.085366
#> [4,] 4.322654 3.993582
#> [5,] 5.013730 4.829268
#> [6,] 4.319603 4.055199
#> [7,] 4.627002 4.872272
#> [8,] 4.148741 4.379974
#> [9,] 4.169336 4.141207
#> [10,] 4.041953 3.768293
#> [11,] 4.127384 4.323492
#> [12,] 4.172387 4.215019
#> [13,] 4.362319 4.260591
#> [14,] 4.335622 4.245828
#> [15,] 3.705568 3.808729
#> [16,] 3.817696 3.688703
#> AGGTCCGAGACGACGT-300.1.1 AGGTCCGAGGCTCTTA-300.1.1
#> [1,] 4.885217 4.741024
#> [2,] 3.704928 3.696292
#> [3,] 3.877101 3.896410
#> [4,] 4.326377 4.337257
#> [5,] 5.410435 5.198352
#> [6,] 3.838261 3.881695
#> [7,] 4.859710 5.029429
#> [8,] 4.303188 4.494997
#> [9,] 3.990145 3.997646
#> [10,] 3.695072 3.906416
#> [11,] 4.101449 4.197763
#> [12,] 4.088116 3.829900
#> [13,] 4.289855 4.164214
#> [14,] 4.326377 4.234844
#> [15,] 3.948986 3.732195
#> [16,] 4.677681 4.118893
#> AGGTCCGGTCGCCATG-300.1.1 AGGTCCGTCAACGGGA-300.1.1
#> [1,] 4.280383 4.572016
#> [2,] 4.242105 3.741329
#> [3,] 4.152153 4.062316
#> [4,] 4.185646 4.179306
#> [5,] 4.367464 5.126984
#> [6,] 4.383732 3.933568
#> [7,] 4.755024 4.891240
#> [8,] 4.622967 4.252792
#> [9,] 4.622010 3.989418
#> [10,] 4.312919 3.656085
#> [11,] 4.235407 4.325691
#> [12,] 4.790431 4.194004
#> [13,] 4.345455 4.243386
#> [14,] 4.120574 4.228689
#> [15,] 4.613397 4.185773
#> [16,] 4.500478 4.370370
#> AGTTGGTAGCCAGTAG-300.1.1 ATAACGCCATGTAGTC-300.1.1
#> [1,] 4.548217 4.926796
#> [2,] 3.738749 3.865331
#> [3,] 3.955582 3.747928
#> [4,] 4.224430 3.975829
#> [5,] 5.206897 5.437155
#> [6,] 3.978960 3.814917
#> [7,] 4.723553 4.691298
#> [8,] 4.145529 4.151934
#> [9,] 4.146698 3.979972
#> [10,] 3.845120 3.660221
#> [11,] 4.476914 4.084945
#> [12,] 4.267680 3.927486
#> [13,] 4.212157 3.987569
#> [14,] 4.459380 4.232044
#> [15,] 3.661017 3.881906
#> [16,] 3.852133 4.760359
#> ATCACGAGTCGAGTTT-300.1.1 ATCACGATCGCCAGCA-300.1.1
#> [1,] 4.797463 4.457093
#> [2,] 3.505211 3.691769
#> [3,] 3.786135 4.073555
#> [4,] 4.077934 4.018097
#> [5,] 5.430449 4.765324
#> [6,] 3.594925 3.852306
#> [7,] 4.907567 4.693520
#> [8,] 4.004078 4.430239
#> [9,] 4.077028 4.401051
#> [10,] 3.777073 3.821950
#> [11,] 3.919801 4.163456
#> [12,] 3.995016 4.041448
#> [13,] 4.351609 4.029772
#> [14,] 4.581785 4.182137
#> [15,] 3.747621 4.016346
#> [16,] 4.371998 3.956801
#> ATCACGATCGGCATCG-300.1.1 ATCCGAAAGCTACCGC-300.1.1
#> [1,] 4.734489 4.740234
#> [2,] 3.743613 4.412109
#> [3,] 4.060219 4.104492
#> [4,] 4.028285 4.026367
#> [5,] 4.870438 4.455078
#> [6,] 3.960766 4.373047
#> [7,] 4.266423 4.514648
#> [8,] 4.582117 4.983398
#> [9,] 4.085766 4.576172
#> [10,] 4.051095 4.426758
#> [11,] 4.063869 4.392578
#> [12,] 4.039234 4.334961
#> [13,] 4.015511 4.624023
#> [14,] 4.032847 4.128906
#> [15,] 4.188869 4.074219
#> [16,] 4.723540 4.812500
#> ATCCGAAAGCTATGCT-300.1.1 ATGAGGGAGGCTAGAC-300.1.1
#> [1,] 4.368442 4.559809
#> [2,] 4.038337 3.898923
#> [3,] 4.236885 4.082536
#> [4,] 4.205004 4.195574
#> [5,] 4.760694 4.648325
#> [6,] 4.074253 4.153110
#> [7,] 4.577885 4.416866
#> [8,] 4.473366 4.559211
#> [9,] 4.156174 4.039474
#> [10,] 4.188862 3.958134
#> [11,] 4.320823 4.044258
#> [12,] 4.231638 3.825957
#> [13,] 4.192897 4.514354
#> [14,] 4.138822 4.084928
#> [15,] 4.006053 4.035287
#> [16,] 4.426554 4.573565
#> ATGAGGGTCCTATGTT-300.1.1 ATGTGTGCAGTCAGAG-300.1.1
#> [1,] 4.622853 4.247373
#> [2,] 3.861955 3.438395
#> [3,] 4.223250 4.027698
#> [4,] 4.077939 4.067335
#> [5,] 4.853369 5.018147
#> [6,] 4.101717 3.963228
#> [7,] 4.781374 4.840974
#> [8,] 4.051519 4.177173
#> [9,] 4.076618 4.041547
#> [10,] 4.081902 3.921203
#> [11,] 4.498679 3.957975
#> [12,] 4.238441 4.314231
#> [13,] 4.376486 4.012894
#> [14,] 4.402246 4.229226
#> [15,] 3.864597 4.567813
#> [16,] 3.576618 4.285578
#> ATTATCCCACCACCAG-300.1.1 ATTATCCGTGACCAAG-300.1.1
#> [1,] 4.503878 4.686028
#> [2,] 3.873655 3.634223
#> [3,] 4.194396 3.897959
#> [4,] 4.126345 4.125065
#> [5,] 4.953215 5.014652
#> [6,] 4.056042 3.835165
#> [7,] 4.872404 4.916274
#> [8,] 4.213910 4.122972
#> [9,] 4.111834 4.151230
#> [10,] 4.134851 3.791209
#> [11,] 4.236177 4.203035
#> [12,] 4.300976 3.992151
#> [13,] 4.408556 4.262166
#> [14,] 4.279960 4.476714
#> [15,] 3.893420 3.685505
#> [16,] 4.083312 4.114600
#> ATTGGACCAGTAACGG-300.1.1 CAACCTCGTCCAGTGC-300.1.1
#> [1,] 4.327030 4.388254
#> [2,] 4.221236 3.932381
#> [3,] 4.331345 4.193968
#> [4,] 4.229915 4.187937
#> [5,] 4.583176 5.180635
#> [6,] 4.230982 4.005397
#> [7,] 4.395879 5.041905
#> [8,] 4.518545 4.113333
#> [9,] 4.400145 4.008889
#> [10,] 4.187782 3.914286
#> [11,] 4.224388 4.230794
#> [12,] 4.334109 4.119365
#> [13,] 4.419830 4.200952
#> [14,] 4.182933 4.248254
#> [15,] 4.209697 3.993651
#> [16,] 4.303224 4.162222
#> CAAGGCCGTCACACGC-300.1.1 CAAGGCCGTCCTCTTG-300.1.1
#> [1,] 4.919012 4.844244
#> [2,] 3.917289 3.866817
#> [3,] 4.333716 4.255643
#> [4,] 4.455485 4.281603
#> [5,] 4.809305 4.632619
#> [6,] 3.875359 4.213318
#> [7,] 4.838599 4.367381
#> [8,] 4.439403 4.363431
#> [9,] 4.145319 4.259594
#> [10,] 4.072372 3.879797
#> [11,] 3.910971 4.260722
#> [12,] 4.106835 4.347630
#> [13,] 4.153935 4.446953
#> [14,] 3.990810 4.002822
#> [15,] 3.839747 3.882054
#> [16,] 3.928202 4.333521
#> CAAGTTGTCTCCGGTT-300.1.1 CACACCTCACATGTGT-300.1.1
#> [1,] 4.890984 4.289976
#> [2,] 3.592456 4.012560
#> [3,] 3.885005 4.189614
#> [4,] 4.252530 4.249638
#> [5,] 5.359246 4.842693
#> [6,] 4.038178 4.071075
#> [7,] 4.711132 4.694444
#> [8,] 4.187213 4.356401
#> [9,] 3.857866 4.301329
#> [10,] 3.706072 4.146014
#> [11,] 4.005060 4.056643
#> [12,] 3.840846 4.223007
#> [13,] 4.126495 4.409843
#> [14,] 4.269549 4.369928
#> [15,] 3.921803 3.937077
#> [16,] 4.291168 4.252053
#> CACACTCGTACCATCA-300.1.1 CACAGGCTCACCCTCA-300.1.1
#> [1,] 4.091575 4.215808
#> [2,] 4.204212 3.976021
#> [3,] 4.049451 4.452931
#> [4,] 4.371337 4.174067
#> [5,] 5.215201 4.683837
#> [6,] 4.114469 4.259325
#> [7,] 4.989011 4.340142
#> [8,] 4.362179 4.613677
#> [9,] 4.101190 4.211368
#> [10,] 3.977106 4.228242
#> [11,] 4.120879 4.007105
#> [12,] 3.927198 4.373002
#> [13,] 4.439560 4.579041
#> [14,] 4.483974 4.060391
#> [15,] 4.054945 4.133215
#> [16,] 4.025183 4.387211
#> CACATAGTCAAGGTAA-300.1.1 CAGCATATCCACGACG-300.1.1
#> [1,] 4.583016 4.360953
#> [2,] 4.174271 3.629966
#> [3,] 4.325095 3.910897
#> [4,] 4.638783 4.232123
#> [5,] 4.913815 5.040863
#> [6,] 3.839037 3.769580
#> [7,] 4.423954 4.857548
#> [8,] 4.634981 4.470488
#> [9,] 4.347275 3.984109
#> [10,] 3.804183 3.943246
#> [11,] 4.072877 3.776958
#> [12,] 4.006337 4.098184
#> [13,] 4.395437 4.418842
#> [14,] 4.141318 4.128263
#> [15,] 3.922687 3.857548
#> [16,] 4.206591 4.085698
#> CAGCCGAGTGACTACT-300.1.1 CAGCGACTCTGAGTGT-300.1.1
#> [1,] 4.312908 4.585227
#> [2,] 4.005957 3.616477
#> [3,] 4.127092 3.972159
#> [4,] 4.113191 4.088068
#> [5,] 5.030071 4.965341
#> [6,] 4.040000 4.305114
#> [7,] 4.930780 4.786364
#> [8,] 4.325390 4.185795
#> [9,] 4.268936 4.213636
#> [10,] 4.038865 3.985227
#> [11,] 4.083404 4.318182
#> [12,] 4.272340 4.051136
#> [13,] 4.277730 4.330682
#> [14,] 4.396879 4.381250
#> [15,] 3.950355 3.765909
#> [16,] 4.252482 3.864773
#> CAGCTAATCCGTTGCT-300.1.1 CAGCTAATCTTCATGT-300.1.1
#> [1,] 4.634716 4.761490
#> [2,] 3.747735 3.939526
#> [3,] 3.814020 4.059023
#> [4,] 4.368145 4.292211
#> [5,] 5.252265 5.122883
#> [6,] 3.768717 3.977262
#> [7,] 4.778732 4.365747
#> [8,] 4.332380 4.413159
#> [9,] 3.936099 3.813256
#> [10,] 3.756795 3.842284
#> [11,] 3.977110 4.091437
#> [12,] 3.904626 3.974843
#> [13,] 4.044826 4.129657
#> [14,] 4.200763 4.187712
#> [15,] 3.964711 4.118529
#> [16,] 4.399619 4.454765
#> CATATGGCAGACAAGC-300.1.1 CATATGGCATTTGCCC-300.1.1
#> [1,] 4.644870 4.545351
#> [2,] 3.699096 3.990873
#> [3,] 3.928761 3.886766
#> [4,] 4.022860 4.404450
#> [5,] 5.005316 4.829720
#> [6,] 3.977140 4.164290
#> [7,] 4.629984 4.399030
#> [8,] 3.990962 4.514261
#> [9,] 4.264753 4.336281
#> [10,] 3.683147 4.060753
#> [11,] 4.276980 3.892755
#> [12,] 4.074428 4.335995
#> [13,] 4.053163 4.355106
#> [14,] 4.215843 4.137193
#> [15,] 3.693780 4.029663
#> [16,] 4.237640 4.469481
#> CATGACACATTAACCG-300.1.1 CATGACATCGATCCCT-300.1.1
#> [1,] 4.354453 4.458612
#> [2,] 4.490137 3.995740
#> [3,] 3.942020 4.133597
#> [4,] 3.848775 4.217285
#> [5,] 4.595338 5.118229
#> [6,] 3.959952 4.037432
#> [7,] 4.196653 4.842818
#> [8,] 4.927077 4.328211
#> [9,] 4.650926 4.076385
#> [10,] 3.750747 3.948113
#> [11,] 4.280932 4.040170
#> [12,] 4.385535 4.098904
#> [13,] 4.566049 4.190353
#> [14,] 4.709504 4.250609
#> [15,] 4.013748 4.003500
#> [16,] 4.604901 4.186853
#> CATGCCTCATATGGTC-300.1.1 CATGCCTGTTAAGGGC-300.1.1
#> [1,] 4.660478 4.656634
#> [2,] 3.863174 3.693514
#> [3,] 4.072005 3.811785
#> [4,] 4.336051 4.447223
#> [5,] 4.986196 5.018652
#> [6,] 3.887875 3.923696
#> [7,] 4.848402 4.621450
#> [8,] 4.253794 4.541755
#> [9,] 4.021472 4.183128
#> [10,] 3.871731 3.835100
#> [11,] 4.148289 3.813480
#> [12,] 4.089845 3.851632
#> [13,] 4.215128 4.067401
#> [14,] 4.210446 4.176346
#> [15,] 4.046981 4.003391
#> [16,] 4.184291 4.038576
#> CATGGCGTCGGCGCAT-300.1.1 CATTATCGTTGGGACA-300.1.1
#> [1,] 4.404084 4.844625
#> [2,] 3.989790 3.844625
#> [3,] 4.004299 4.286410
#> [4,] 4.047824 4.371197
#> [5,] 5.254702 5.369574
#> [6,] 4.032778 3.997972
#> [7,] 4.957012 5.003245
#> [8,] 4.216550 3.825558
#> [9,] 3.980118 3.965112
#> [10,] 3.960774 3.945639
#> [11,] 4.132187 3.910751
#> [12,] 3.839871 4.168763
#> [13,] 4.162816 4.431643
#> [14,] 4.261150 4.081947
#> [15,] 4.040838 3.733874
#> [16,] 4.521225 4.083976
#> CCAATCCAGATGCCTT-300.1.1 CCAATCCCACCTCGTT-300.1.1
#> [1,] 4.439916 4.678594
#> [2,] 4.490513 3.774639
#> [3,] 4.309206 4.204018
#> [4,] 4.102600 3.987445
#> [5,] 4.511595 4.740113
#> [6,] 4.009838 3.993095
#> [7,] 4.092762 4.675455
#> [8,] 4.889670 4.268048
#> [9,] 4.524947 4.305712
#> [10,] 4.043570 3.940364
#> [11,] 4.252284 4.358443
#> [12,] 4.045678 4.270559
#> [13,] 4.562895 4.246704
#> [14,] 4.047786 4.168236
#> [15,] 4.063949 3.863779
#> [16,] 4.532677 4.224733
#> CCACGGATCTTGTTTG-300.1.1 CCAGCGAGTTAGTGGG-300.1.1
#> [1,] 4.844517 4.726659
#> [2,] 4.252864 3.647919
#> [3,] 4.217676 3.926322
#> [4,] 4.094926 4.240157
#> [5,] 4.581015 4.620922
#> [6,] 3.738953 4.119235
#> [7,] 4.205401 4.730596
#> [8,] 4.380524 4.251969
#> [9,] 4.211129 4.232846
#> [10,] 4.005728 3.888639
#> [11,] 3.905074 3.745219
#> [12,] 4.210311 4.071429
#> [13,] 4.270867 4.363892
#> [14,] 4.049100 4.289089
#> [15,] 4.342881 3.908886
#> [16,] 4.528642 4.231159
#> CCCAATCAGATCCCGC-300.1.1 CCCAGTTTCCTTTCGG-300.1.1
#> [1,] 4.553707 4.192177
#> [2,] 4.155825 4.347789
#> [3,] 4.242814 4.326531
#> [4,] 4.567322 4.238095
#> [5,] 4.586989 4.733844
#> [6,] 4.330560 4.280612
#> [7,] 4.043116 4.285714
#> [8,] 4.910741 4.380102
#> [9,] 4.380484 3.965986
#> [10,] 4.368381 4.229592
#> [11,] 4.430408 4.255102
#> [12,] 4.303328 4.335034
#> [13,] 4.531770 4.023810
#> [14,] 3.941755 3.982143
#> [15,] 4.226172 4.070578
#> [16,] 4.524962 3.861395
#> CCCATACAGCGCCTTG-300.1.1 CCCTCCTAGAGAGCTC-300.1.1
#> [1,] 4.290000 4.952775
#> [2,] 3.829091 3.620547
#> [3,] 3.861818 3.873239
#> [4,] 4.361818 4.337200
#> [5,] 4.865455 5.408451
#> [6,] 3.987727 4.097763
#> [7,] 5.132727 4.727423
#> [8,] 4.361818 4.399337
#> [9,] 4.077273 3.947804
#> [10,] 3.840455 3.899751
#> [11,] 4.205000 3.906379
#> [12,] 3.869091 3.739851
#> [13,] 4.153636 4.253521
#> [14,] 4.351818 4.211268
#> [15,] 3.820455 4.045568
#> [16,] 4.026364 4.533554
#> CCCTCCTCACCCATGG-300.1.1 CCGTACTGTCGCGGTT-300.1.1
#> [1,] 4.474558 4.302564
#> [2,] 3.740225 4.060073
#> [3,] 4.122657 3.567033
#> [4,] 4.333155 3.860806
#> [5,] 4.790037 5.008791
#> [6,] 3.954472 3.915018
#> [7,] 5.010712 4.920879
#> [8,] 3.997858 4.350916
#> [9,] 4.000536 4.066667
#> [10,] 3.876808 3.731868
#> [11,] 3.957686 4.270330
#> [12,] 3.818961 3.775092
#> [13,] 4.282271 3.909158
#> [14,] 4.141939 4.655678
#> [15,] 3.906802 3.564103
#> [16,] 4.206213 4.052747
#> CCGTGGACACCTCGTT-300.1.1 CCGTTCAAGACGCACA-300.1.1
#> [1,] 4.602671 4.738122
#> [2,] 3.910963 3.660773
#> [3,] 4.184196 4.128177
#> [4,] 4.387869 4.198343
#> [5,] 5.038397 4.787293
#> [6,] 3.761269 4.011602
#> [7,] 5.066221 4.857459
#> [8,] 4.076795 4.229282
#> [9,] 4.047301 4.197790
#> [10,] 3.884252 3.993370
#> [11,] 3.993879 4.259669
#> [12,] 4.148024 4.126519
#> [13,] 4.134112 4.332597
#> [14,] 4.158041 4.421547
#> [15,] 3.925988 4.004972
#> [16,] 4.134669 3.965746
#> CCTATTATCTACTTAC-300.1.1 CCTCAGTAGTGTGAAT-300.1.1
#> [1,] 5.122330 4.656960
#> [2,] 3.519094 3.809276
#> [3,] 3.971521 3.894196
#> [4,] 4.209709 4.311154
#> [5,] 5.097087 5.056987
#> [6,] 3.886731 3.827591
#> [7,] 4.642071 4.865472
#> [8,] 4.340453 4.258779
#> [9,] 4.214239 4.138349
#> [10,] 3.577346 3.804598
#> [11,] 4.000647 4.087753
#> [12,] 4.106796 3.936359
#> [13,] 4.132686 4.239739
#> [14,] 4.006472 4.293168
#> [15,] 4.120388 3.922920
#> [16,] 4.383819 4.013506
#> CCTCAGTGTTGTCGCG-300.1.1 CCTCTGAAGCTCAACT-300.1.1
#> [1,] 4.316973 4.434911
#> [2,] 3.946149 4.064349
#> [3,] 4.476483 4.093935
#> [4,] 4.205862 4.177515
#> [5,] 4.406271 4.488905
#> [6,] 3.932515 4.019970
#> [7,] 4.247444 4.440089
#> [8,] 4.665303 4.520710
#> [9,] 4.217451 4.375740
#> [10,] 4.229039 4.350592
#> [11,] 3.997955 3.970414
#> [12,] 4.329243 4.244822
#> [13,] 4.178596 4.527367
#> [14,] 4.132243 4.093935
#> [15,] 4.441036 4.121302
#> [16,] 4.116564 4.732988
#> CCTCTGATCCTCGCAT-300.1.1 CCTTCCCCATCGGAAG-300.1.1
#> [1,] 4.510611 4.471459
#> [2,] 3.757640 3.689922
#> [3,] 3.879457 3.843552
#> [4,] 4.208404 4.663143
#> [5,] 5.341256 5.117689
#> [6,] 4.132428 3.968992
#> [7,] 5.028438 5.129669
#> [8,] 4.177844 4.203665
#> [9,] 4.004669 4.143763
#> [10,] 3.760187 3.977449
#> [11,] 3.966893 3.918252
#> [12,] 3.764431 3.713178
#> [13,] 4.083616 4.121917
#> [14,] 4.267402 4.272727
#> [15,] 3.977080 3.663143
#> [16,] 4.114177 3.881607
#> CCTTTCTCAATTCCTT-300.1.1 CGAGCCAGTAAGTGTA-300.1.1
#> [1,] 4.273535 4.597203
#> [2,] 4.336590 3.917016
#> [3,] 4.153641 4.287179
#> [4,] 4.243339 4.255478
#> [5,] 4.464476 4.728205
#> [6,] 4.484902 4.147786
#> [7,] 4.515986 4.354779
#> [8,] 4.865897 4.557110
#> [9,] 4.828597 4.158508
#> [10,] 4.229130 4.159907
#> [11,] 4.526643 4.226107
#> [12,] 4.589698 4.348252
#> [13,] 4.210480 4.323543
#> [14,] 4.122558 4.311888
#> [15,] 4.059503 4.194872
#> [16,] 4.446714 4.182751
#> CGAGCCATCGGCGCAT-300.1.1 CGCCAAGCAGATAATG-300.1.1
#> [1,] 4.675225 4.470336
#> [2,] 3.772144 3.837920
#> [3,] 3.854300 3.598471
#> [4,] 4.035944 4.041590
#> [5,] 5.388318 5.596024
#> [6,] 4.118100 3.888685
#> [7,] 4.831836 5.360245
#> [8,] 4.100128 4.311621
#> [9,] 4.007702 4.014067
#> [10,] 3.869063 3.733945
#> [11,] 4.219512 3.867278
#> [12,] 3.865854 3.773700
#> [13,] 4.302311 4.285015
#> [14,] 4.324775 4.485321
#> [15,] 3.989730 3.669113
#> [16,] 4.476893 3.695413
#> CGCGGTAAGCGTAGTG-300.1.1 CGCGTTTCAGGAACGT-300.1.1
#> [1,] 4.896978 4.315447
#> [2,] 3.622253 4.025366
#> [3,] 3.722527 4.402276
#> [4,] 4.081731 4.130081
#> [5,] 5.364698 5.013008
#> [6,] 3.842720 3.875772
#> [7,] 5.036401 4.804228
#> [8,] 4.117445 4.252358
#> [9,] 3.918956 4.150244
#> [10,] 3.878434 3.804228
#> [11,] 4.102335 4.082602
#> [12,] 3.729396 4.385691
#> [13,] 4.200549 4.156748
#> [14,] 4.395604 4.189268
#> [15,] 3.848901 4.202276
#> [16,] 4.289835 4.594472
#> CGCTATCCAGTAAGAT-300.1.1 CGCTATCTCTGCTGCT-300.1.1
#> [1,] 4.225806 4.541739
#> [2,] 3.936013 3.911917
#> [3,] 4.258065 3.804836
#> [4,] 4.162348 3.911341
#> [5,] 4.665785 5.310881
#> [6,] 4.027499 4.088083
#> [7,] 4.668958 4.788140
#> [8,] 4.385510 4.393207
#> [9,] 4.063987 3.995394
#> [10,] 4.102591 3.763385
#> [11,] 4.053940 4.155440
#> [12,] 4.281861 3.994819
#> [13,] 4.390799 4.166379
#> [14,] 3.987308 4.337363
#> [15,] 4.098361 3.863558
#> [16,] 4.333157 4.309154
#> CGCTGGACACTAAGTC-300.1.1 CGCTGGACAGACGCAA-300.1.1
#> [1,] 4.716948 4.358722
#> [2,] 3.882935 4.377559
#> [3,] 3.868375 3.865684
#> [4,] 4.090274 4.050778
#> [5,] 5.175306 4.357903
#> [6,] 3.876529 3.904177
#> [7,] 4.525335 4.374283
#> [8,] 4.184042 4.507781
#> [9,] 3.923704 4.098280
#> [10,] 3.831101 4.023751
#> [11,] 4.323821 3.884521
#> [12,] 3.704718 4.203112
#> [13,] 4.068725 4.420966
#> [14,] 4.373908 4.130221
#> [15,] 3.951660 4.269451
#> [16,] 4.425743 4.627355
#> CGCTGGAGTCGGCTCA-300.1.1 CGCTGGAGTTAAGACA-300.1.1
#> [1,] 4.506160 4.433472
#> [2,] 3.713039 3.789986
#> [3,] 3.814168 4.251275
#> [4,] 4.397844 4.179416
#> [5,] 5.075462 4.621233
#> [6,] 3.929158 4.044043
#> [7,] 4.953285 4.562819
#> [8,] 4.147331 4.194251
#> [9,] 4.200205 4.173853
#> [10,] 3.809035 3.917942
#> [11,] 4.221766 4.057024
#> [12,] 3.928131 4.287900
#> [13,] 4.119097 4.375985
#> [14,] 4.385010 4.021790
#> [15,] 3.667351 4.362541
#> [16,] 3.869097 4.472879
#> CGCTTCAGTTATCCGA-300.1.1 CGGACGTAGTACGTAA-300.1.1
#> [1,] 4.452754 4.373333
#> [2,] 3.717681 3.849524
#> [3,] 3.950725 4.181905
#> [4,] 4.166957 4.242857
#> [5,] 5.182609 4.757143
#> [6,] 3.812754 3.972381
#> [7,] 4.997681 4.803810
#> [8,] 4.211594 4.340000
#> [9,] 4.013333 4.155238
#> [10,] 3.756522 4.194286
#> [11,] 3.817971 4.478095
#> [12,] 4.002899 4.183810
#> [13,] 4.422609 4.302857
#> [14,] 4.113623 4.185714
#> [15,] 4.007536 4.286667
#> [16,] 4.326377 4.370476
#> CGGACGTAGTGGTCCC-300.1.1 CGGAGCTCAATGGAAT-300.1.1
#> [1,] 4.119712 4.364591
#> [2,] 4.153915 3.794714
#> [3,] 4.365437 3.900072
#> [4,] 4.237624 4.259957
#> [5,] 4.590459 4.902607
#> [6,] 4.292529 4.001086
#> [7,] 4.249325 4.955829
#> [8,] 4.093609 4.274077
#> [9,] 4.192619 4.157495
#> [10,] 4.285329 3.902245
#> [11,] 4.273627 3.821868
#> [12,] 4.336634 3.956915
#> [13,] 4.053105 4.446054
#> [14,] 4.017102 4.307024
#> [15,] 4.086409 4.010862
#> [16,] 4.226823 4.266474
#> CGGAGTCAGTCGCCGT-300.1.1 CGGAGTCTCTGTACGA-300.1.1
#> [1,] 4.622922 4.621603
#> [2,] 3.788276 3.756114
#> [3,] 3.900262 4.108696
#> [4,] 4.213473 4.308424
#> [5,] 5.386702 5.233696
#> [6,] 3.987752 3.993207
#> [7,] 4.565179 5.097826
#> [8,] 4.148731 3.996603
#> [9,] 4.120735 4.161005
#> [10,] 3.815398 3.690217
#> [11,] 4.104112 3.864810
#> [12,] 4.048994 4.121603
#> [13,] 4.081365 4.392663
#> [14,] 4.055118 4.167120
#> [15,] 3.873141 4.105299
#> [16,] 4.342957 4.317255
#> CGGCTAGCAACTTGAC-300.1.1 CGTCACTCATGTTCCC-300.1.1
#> [1,] 4.996973 4.162133
#> [2,] 3.477296 4.001067
#> [3,] 4.214934 3.922133
#> [4,] 4.188698 4.067733
#> [5,] 5.125126 5.558933
#> [6,] 3.703330 4.033067
#> [7,] 4.312815 5.260267
#> [8,] 4.395560 4.138667
#> [9,] 3.901110 4.005333
#> [10,] 3.713421 4.018133
#> [11,] 3.934410 3.992000
#> [12,] 3.840565 3.900800
#> [13,] 4.048436 4.369600
#> [14,] 4.121090 4.567467
#> [15,] 4.169526 3.816533
#> [16,] 4.298688 3.905067
#> CGTCAGGGTAAGGATT-300.1.1 CGTCTACTCCAGTAGT-300.1.1
#> [1,] 4.417709 4.403462
#> [2,] 4.387873 4.011318
#> [3,] 4.489894 3.958056
#> [4,] 4.485082 4.017976
#> [5,] 4.619827 4.415446
#> [6,] 4.342637 4.023968
#> [7,] 3.976901 4.203063
#> [8,] 4.887392 4.579893
#> [9,] 4.559192 4.121172
#> [10,] 4.384023 4.238349
#> [11,] 4.341675 4.163116
#> [12,] 4.206930 4.131158
#> [13,] 4.410972 4.328895
#> [14,] 4.232916 3.976698
#> [15,] 4.205967 4.137816
#> [16,] 4.514918 4.397470
#> CGTGTAATCGTTACGA-300.1.1 CGTTAGAAGGCGTACA-300.1.1
#> [1,] 4.787479 4.310421
#> [2,] 3.486820 3.859756
#> [3,] 4.447282 4.165188
#> [4,] 4.616969 4.456763
#> [5,] 5.146623 4.919623
#> [6,] 3.813015 4.028271
#> [7,] 4.654036 4.904102
#> [8,] 4.089786 4.274945
#> [9,] 4.050247 4.021619
#> [10,] 3.708402 3.988359
#> [11,] 4.200165 3.890798
#> [12,] 3.950577 3.829268
#> [13,] 4.085667 4.320953
#> [14,] 4.105437 4.380266
#> [15,] 4.079077 3.767738
#> [16,] 4.588138 4.035477
#> CTAAGACAGCACCGCT-300.1.1 CTAAGACCAGCTTCGG-300.1.1
#> [1,] 4.511568 4.821676
#> [2,] 3.793059 3.463962
#> [3,] 3.928663 4.167645
#> [4,] 4.154884 4.272290
#> [5,] 5.408740 4.853711
#> [6,] 4.099614 4.238121
#> [7,] 4.792416 4.495462
#> [8,] 4.113753 4.067806
#> [9,] 3.999357 4.124399
#> [10,] 3.850257 3.864389
#> [11,] 4.134319 4.308596
#> [12,] 4.033419 4.167645
#> [13,] 4.334190 4.408436
#> [14,] 4.217866 4.175654
#> [15,] 3.961440 3.704218
#> [16,] 4.347686 3.829151
#> CTAAGACTCTCTAGGA-300.1.1 CTAATGGAGGGCTTCC-300.1.1
#> [1,] 4.705582 4.372253
#> [2,] 3.906359 4.327610
#> [3,] 3.874463 4.379808
#> [4,] 4.226743 4.439560
#> [5,] 4.967696 4.626374
#> [6,] 3.868534 4.048764
#> [7,] 4.601104 4.604396
#> [8,] 4.249029 4.201236
#> [9,] 4.197915 4.242445
#> [10,] 3.829687 4.316621
#> [11,] 4.046821 4.451923
#> [12,] 4.037620 4.013049
#> [13,] 4.280924 4.201236
#> [14,] 4.206502 4.581731
#> [15,] 3.845839 3.938187
#> [16,] 4.158250 4.129808
#> CTAATGGAGTACCGGA-300.1.1 CTACCCACAATGGACG-300.1.1
#> [1,] 4.306954 4.259391
#> [2,] 4.141375 4.165131
#> [3,] 4.103342 4.265769
#> [4,] 4.420284 4.231751
#> [5,] 4.665770 4.367116
#> [6,] 4.234729 4.136782
#> [7,] 4.392624 4.184266
#> [8,] 4.573569 4.649894
#> [9,] 4.364579 4.521616
#> [10,] 4.212063 4.396882
#> [11,] 4.105647 4.160170
#> [12,] 4.366116 4.253012
#> [13,] 4.405686 4.620128
#> [14,] 4.124856 4.263643
#> [15,] 4.278141 4.317505
#> [16,] 4.721475 4.781006
#> CTACCCAGTCTGGAGA-300.1.1 CTACCCATCTGGGCCA-300.1.1
#> [1,] 4.333012 4.183068
#> [2,] 3.972008 4.017728
#> [3,] 4.273166 4.136035
#> [4,] 4.098938 4.098046
#> [5,] 4.544402 5.073444
#> [6,] 4.029440 3.993126
#> [7,] 4.343147 4.943560
#> [8,] 4.363900 4.325253
#> [9,] 4.275579 4.208755
#> [10,] 3.952703 3.948987
#> [11,] 4.138996 4.201881
#> [12,] 4.331564 4.148336
#> [13,] 4.229730 4.136035
#> [14,] 3.955116 4.329595
#> [15,] 4.243726 3.831404
#> [16,] 4.430502 4.220695
#> CTAGTGATCCGCGCAA-300.1.1 CTCATTACAGTATGCT-300.1.1
#> [1,] 4.389666 4.260960
#> [2,] 3.585038 3.947860
#> [3,] 3.814855 4.076005
#> [4,] 4.287406 4.149935
#> [5,] 4.991927 5.289494
#> [6,] 3.889128 4.185733
#> [7,] 5.043595 4.948379
#> [8,] 4.127018 4.233722
#> [9,] 4.076426 4.314656
#> [10,] 3.752960 4.094423
#> [11,] 3.924112 4.132036
#> [12,] 3.844995 4.157198
#> [13,] 4.298170 4.223087
#> [14,] 3.971475 4.395331
#> [15,] 3.850377 4.065888
#> [16,] 4.200215 4.079118
#> CTCCTAGTCACCTTAT-300.1.1 CTCGAGGAGGAGTTGC-300.1.1
#> [1,] 4.726634 4.706748
#> [2,] 4.100492 3.650920
#> [3,] 4.189037 3.951534
#> [4,] 4.122980 4.236810
#> [5,] 4.541813 5.057055
#> [6,] 3.987351 3.673620
#> [7,] 4.255798 5.143558
#> [8,] 4.570625 4.171166
#> [9,] 4.382994 3.974847
#> [10,] 3.988756 3.804294
#> [11,] 3.999297 4.143558
#> [12,] 3.928320 4.116564
#> [13,] 4.297962 4.184049
#> [14,] 4.075896 4.415337
#> [15,] 4.113141 3.889571
#> [16,] 4.458187 4.112883
#> CTCGAGGAGTGATCGG-300.1.1 CTCGAGGGTCTTCGTC-300.1.1
#> [1,] 4.510035 4.303215
#> [2,] 3.513577 3.617517
#> [3,] 3.539551 3.930155
#> [4,] 4.369540 4.292129
#> [5,] 4.969894 5.010532
#> [6,] 3.915584 3.963969
#> [7,] 5.204250 4.598115
#> [8,] 4.307556 4.342572
#> [9,] 4.333530 4.093681
#> [10,] 3.839433 3.978381
#> [11,] 4.214286 4.011086
#> [12,] 3.642857 4.028271
#> [13,] 4.191263 4.263858
#> [14,] 4.482881 4.175166
#> [15,] 3.384888 3.764967
#> [16,] 3.969894 4.212860
#> CTCGTCAAGTCTCCTC-300.1.1 CTGAAACCAGCCAATT-300.1.1
#> [1,] 4.943662 4.144869
#> [2,] 3.593470 4.116700
#> [3,] 3.834187 4.045607
#> [4,] 3.994238 4.203890
#> [5,] 5.159411 4.340711
#> [6,] 3.932138 4.173038
#> [7,] 4.699744 4.407780
#> [8,] 4.173496 4.568746
#> [9,] 4.147247 4.099262
#> [10,] 3.604353 4.540577
#> [11,] 3.911652 4.075788
#> [12,] 3.943022 4.285044
#> [13,] 4.033291 4.209256
#> [14,] 4.293854 4.185781
#> [15,] 3.908451 4.014085
#> [16,] 4.355954 4.619718
#> CTGAAGTCACCAGGCT-300.1.1 CTGATAGAGAGCTGGT-300.1.1
#> [1,] 4.674834 4.532854
#> [2,] 4.085430 4.339836
#> [3,] 4.360927 4.283368
#> [4,] 4.237748 4.180698
#> [5,] 4.819205 4.430185
#> [6,] 4.964238 4.596509
#> [7,] 4.247020 4.188912
#> [8,] 5.007285 5.026694
#> [9,] 4.871523 4.597536
#> [10,] 4.578808 4.568789
#> [11,] 4.798675 4.225873
#> [12,] 4.422517 4.422998
#> [13,] 3.946358 4.394251
#> [14,] 4.696026 4.494867
#> [15,] 4.352318 4.300821
#> [16,] 4.411921 4.883984
#> CTGCCTAAGGGTCGAT-300.1.1 CTGCTGTAGCAGGCTA-300.1.1
#> [1,] 4.664256 4.212511
#> [2,] 4.054852 3.916881
#> [3,] 4.128993 3.670951
#> [4,] 3.971067 3.847472
#> [5,] 5.116335 5.023136
#> [6,] 4.122966 3.881748
#> [7,] 4.286920 4.922022
#> [8,] 4.329114 4.287061
#> [9,] 3.935503 4.062554
#> [10,] 3.883665 3.653813
#> [11,] 4.051838 4.155955
#> [12,] 3.961423 3.700943
#> [13,] 4.227245 3.810626
#> [14,] 4.198915 4.561268
#> [15,] 4.053044 3.779777
#> [16,] 4.681133 3.970865
#> CTGCTGTAGTTGTAGA-300.1.1 CTGCTGTCAGAGTGTG-300.1.1
#> [1,] 4.445221 4.265436
#> [2,] 3.663170 4.299481
#> [3,] 3.877622 4.574149
#> [4,] 4.101399 4.245239
#> [5,] 4.850233 4.643393
#> [6,] 3.908508 4.477207
#> [7,] 5.053613 4.327178
#> [8,] 4.345571 4.748413
#> [9,] 4.016317 4.699365
#> [10,] 3.982517 4.239469
#> [11,] 4.138695 4.381997
#> [12,] 3.786713 4.494518
#> [13,] 4.495338 4.143681
#> [14,] 4.324592 4.134449
#> [15,] 3.871795 4.118869
#> [16,] 4.056527 4.526832
#> CTGCTGTTCAAGCCTA-300.1.1 CTGGTCTGTTCCACAA-300.1.1
#> [1,] 4.420040 4.457565
#> [2,] 4.036230 3.750000
#> [3,] 4.093122 4.186808
#> [4,] 4.235777 3.946956
#> [5,] 5.082649 4.850092
#> [6,] 4.307954 4.219557
#> [7,] 5.149165 4.579336
#> [8,] 4.215964 4.324262
#> [9,] 4.234362 4.232011
#> [10,] 4.300028 3.954336
#> [11,] 4.317577 4.367159
#> [12,] 4.120860 4.225092
#> [13,] 4.359185 4.433118
#> [14,] 4.163034 4.004151
#> [15,] 4.012454 4.070572
#> [16,] 3.976790 4.003229
#> CTGGTCTTCGGCGGTT-300.1.1 CTGTGCTAGCTTTGGT-300.1.1
#> [1,] 5.106022 4.541985
#> [2,] 3.946565 3.974809
#> [3,] 3.983885 4.064885
#> [4,] 4.039864 4.101527
#> [5,] 5.299406 5.015267
#> [6,] 3.848176 3.963359
#> [7,] 4.429177 4.784733
#> [8,] 4.234945 4.314504
#> [9,] 3.624258 4.222901
#> [10,] 3.793893 3.819847
#> [11,] 4.167091 4.150382
#> [12,] 3.862595 3.950382
#> [13,] 4.033079 4.358015
#> [14,] 4.279898 4.097710
#> [15,] 4.360475 3.845038
#> [16,] 4.748092 4.351908
#> CTGTGCTGTTGGGACA-300.1.1 CTTACCGCATGCCTTC-300.1.1
#> [1,] 4.553081 4.777397
#> [2,] 3.726058 4.083659
#> [3,] 3.890869 4.265166
#> [4,] 4.284336 4.267613
#> [5,] 5.010393 4.981409
#> [6,] 3.682999 4.109100
#> [7,] 4.869339 4.345401
#> [8,] 4.447661 4.242661
#> [9,] 4.349666 3.935421
#> [10,] 3.593170 3.870352
#> [11,] 4.281366 4.227495
#> [12,] 4.053452 3.969178
#> [13,] 4.109874 4.126712
#> [14,] 4.187082 4.179061
#> [15,] 3.579065 4.055284
#> [16,] 3.794358 4.608611
#> CTTACCGTCCGTCATC-300.1.1 CTTACCGTCGTACGGC-300.1.1
#> [1,] 4.160079 4.677632
#> [2,] 4.263505 4.019737
#> [3,] 4.144269 4.178644
#> [4,] 4.084980 4.280364
#> [5,] 4.303689 4.659919
#> [6,] 4.648221 3.925607
#> [7,] 4.633729 4.362854
#> [8,] 5.000659 4.449899
#> [9,] 4.507246 4.080466
#> [10,] 4.467062 4.115385
#> [11,] 4.451252 3.988866
#> [12,] 4.613966 4.446356
#> [13,] 4.000000 4.192308
#> [14,] 4.179842 3.885121
#> [15,] 4.107378 4.548583
#> [16,] 4.332675 4.481781
#> CTTAGGACATCATCCC-300.1.1 CTTAGGAGTAGCTTGT-300.1.1
#> [1,] 4.385293 4.386970
#> [2,] 4.060073 3.839091
#> [3,] 4.411186 3.996283
#> [4,] 4.222165 4.132707
#> [5,] 4.873123 4.891561
#> [6,] 4.034179 3.958024
#> [7,] 4.740549 4.943594
#> [8,] 4.486794 4.275907
#> [9,] 4.364578 4.187145
#> [10,] 4.118591 3.733931
#> [11,] 4.415847 4.206384
#> [12,] 4.397204 4.100350
#> [13,] 4.033661 4.106034
#> [14,] 4.266701 4.404897
#> [15,] 4.063180 3.880192
#> [16,] 4.239254 4.016178
#> CTTAGGAGTAGGAGTC-300.1.1 CTTAGGAGTTAGTGGG-300.1.1
#> [1,] 4.310047 4.389736
#> [2,] 3.742543 3.603733
#> [3,] 4.109890 3.659720
#> [4,] 4.217425 4.126594
#> [5,] 5.143642 5.591291
#> [6,] 3.943485 4.090824
#> [7,] 4.357928 5.478072
#> [8,] 4.069074 4.050700
#> [9,] 4.079278 3.998756
#> [10,] 3.942700 3.867807
#> [11,] 4.016484 4.000622
#> [12,] 4.175039 3.961431
#> [13,] 4.176609 4.178227
#> [14,] 4.459184 4.417729
#> [15,] 3.695447 3.786625
#> [16,] 4.219780 3.894246
#> CTTCTCTGTTACTGAC-300.1.1 CTTTGCGCAACGCACC-300.1.1
#> [1,] 4.578293 4.121212
#> [2,] 3.788732 4.595520
#> [3,] 4.328915 4.305007
#> [4,] 4.225352 4.188406
#> [5,] 5.324772 4.506588
#> [6,] 4.182270 3.965086
#> [7,] 5.193869 4.434124
#> [8,] 4.023198 4.681159
#> [9,] 4.269263 4.268116
#> [10,] 3.972659 4.065876
#> [11,] 4.011599 4.500659
#> [12,] 3.990886 4.219368
#> [13,] 4.043082 4.300395
#> [14,] 4.378625 4.242424
#> [15,] 3.662800 4.133070
#> [16,] 3.994200 4.210145
#> GACAGAGCATGCTAGT-300.1.1 GACGCGTAGAAGGCCT-300.1.1
#> [1,] 4.430936 4.326162
#> [2,] 3.791852 3.933735
#> [3,] 4.152769 3.925990
#> [4,] 4.355824 3.905336
#> [5,] 4.886060 5.018072
#> [6,] 4.101209 3.604131
#> [7,] 4.864418 5.117040
#> [8,] 4.187778 4.633391
#> [9,] 4.342457 4.378657
#> [10,] 3.894335 3.685026
#> [11,] 4.173138 4.123064
#> [12,] 3.921069 3.840792
#> [13,] 4.011458 3.928571
#> [14,] 4.418842 4.889845
#> [15,] 3.676003 3.612737
#> [16,] 4.080840 3.844234
#> GACGCGTTCTTCTGGC-300.1.1 GACGGCTGTAGTGAAT-300.1.1
#> [1,] 3.994392 4.288404
#> [2,] 4.426725 3.972250
#> [3,] 3.984882 4.235877
#> [4,] 4.095830 4.297324
#> [5,] 5.137040 4.173439
#> [6,] 3.873446 4.193261
#> [7,] 4.632529 4.425173
#> [8,] 4.687637 4.861249
#> [9,] 4.039259 4.549058
#> [10,] 3.978054 4.428147
#> [11,] 4.448915 4.442022
#> [12,] 3.972933 4.524281
#> [13,] 4.177274 4.730426
#> [14,] 4.716898 4.135778
#> [15,] 3.678859 4.317146
#> [16,] 4.172397 4.467790
#> GACGTGCTCGTGGACC-300.1.1 GACGTTACAAACAACA-300.1.1
#> [1,] 4.641904 4.359209
#> [2,] 3.737086 4.363775
#> [3,] 4.094022 4.188737
#> [4,] 4.135229 4.235160
#> [5,] 4.807313 4.474886
#> [6,] 4.280905 4.319635
#> [7,] 4.493326 4.027397
#> [8,] 4.482879 4.837139
#> [9,] 4.136970 4.780822
#> [10,] 4.065003 4.374429
#> [11,] 4.449797 4.238204
#> [12,] 4.400464 4.513699
#> [13,] 4.190946 4.598935
#> [14,] 4.017411 3.939878
#> [15,] 4.084156 4.076104
#> [16,] 4.396982 4.586758
#> GAGCAGAAGGCTCTTA-300.1.1 GAGTCCGCAGCTTCGG-300.1.1
#> [1,] 4.899899 4.360321
#> [2,] 3.687123 4.030284
#> [3,] 4.146378 4.079110
#> [4,] 4.143360 4.540173
#> [5,] 4.608652 4.538937
#> [6,] 4.134809 4.268232
#> [7,] 4.451710 4.314586
#> [8,] 4.322938 4.553770
#> [9,] 4.193159 4.330655
#> [10,] 3.938632 4.104450
#> [11,] 4.403421 4.030902
#> [12,] 4.210765 4.158838
#> [13,] 4.269618 4.362794
#> [14,] 4.019115 3.886897
#> [15,] 4.037223 4.184796
#> [16,] 4.003521 4.556860
#> GATCGTACAACTGCGC-300.1.1 GATGCTACAACACCCG-300.1.1
#> [1,] 4.403630 4.921893
#> [2,] 4.214347 3.801026
#> [3,] 4.378565 4.176739
#> [4,] 4.363008 4.254276
#> [5,] 4.429559 4.842645
#> [6,] 3.931720 4.399658
#> [7,] 4.460674 4.449259
#> [8,] 4.404494 4.178449
#> [9,] 4.330164 4.206956
#> [10,] 3.901469 4.125428
#> [11,] 4.060501 4.490308
#> [12,] 4.153846 4.506842
#> [13,] 4.319793 4.494299
#> [14,] 4.152982 3.817560
#> [15,] 3.930856 3.972064
#> [16,] 4.411409 4.148803
#> GCAAACTAGAGTACCG-300.1.1 GCACATACATTTCACT-300.1.1
#> [1,] 4.603321 4.934704
#> [2,] 3.987673 3.211825
#> [3,] 4.215545 3.565553
#> [4,] 4.330252 4.144473
#> [5,] 4.780175 5.635476
#> [6,] 4.018490 3.819537
#> [7,] 4.569594 4.895630
#> [8,] 4.388118 3.937275
#> [9,] 4.039548 3.940360
#> [10,] 3.861839 3.513111
#> [11,] 3.952234 3.873522
#> [12,] 4.137476 3.678149
#> [13,] 4.224105 3.908483
#> [14,] 4.066769 4.510540
#> [15,] 4.203561 3.814910
#> [16,] 4.172231 4.347558
#> GCACATAGTTTGGCGC-300.1.1 GCACTCTAGGCGTACA-300.1.1
#> [1,] 4.730745 4.506215
#> [2,] 3.820288 4.223066
#> [3,] 3.934252 4.187155
#> [4,] 4.212899 4.049724
#> [5,] 4.777708 4.760359
#> [6,] 4.336882 3.920580
#> [7,] 4.528491 3.988260
#> [8,] 4.262993 4.500691
#> [9,] 4.201002 4.314917
#> [10,] 4.103319 3.719613
#> [11,] 4.318096 3.867403
#> [12,] 4.105197 3.959945
#> [13,] 4.536005 4.718232
#> [14,] 4.007514 3.850138
#> [15,] 3.993112 4.040746
#> [16,] 4.275517 4.557320
#> GCAGCCAAGAAGGTGA-300.1.1 GCAGTTAAGCGAGAAA-300.1.1
#> [1,] 4.682259 4.400941
#> [2,] 3.961209 3.963551
#> [3,] 3.920137 4.300412
#> [4,] 4.121506 4.346267
#> [5,] 5.084997 4.557907
#> [6,] 4.087849 4.089359
#> [7,] 4.561894 4.296884
#> [8,] 4.275528 4.382128
#> [9,] 4.065031 4.400353
#> [10,] 3.909298 4.318048
#> [11,] 4.276098 4.198119
#> [12,] 4.045066 4.279248
#> [13,] 4.324586 4.318048
#> [14,] 4.346834 4.313345
#> [15,] 4.031375 4.039389
#> [16,] 4.343982 4.225162
#> GCATACAAGGCCGAAT-300.1.1 GCATGTAGTACATCCA-300.1.1
#> [1,] 4.878481 4.244461
#> [2,] 3.781646 3.798006
#> [3,] 3.809494 3.906204
#> [4,] 4.438608 3.976736
#> [5,] 4.772152 5.536928
#> [6,] 3.770253 4.201625
#> [7,] 4.327215 5.256647
#> [8,] 4.225316 4.195716
#> [9,] 4.240506 3.951994
#> [10,] 3.875949 3.977843
#> [11,] 3.905696 4.150295
#> [12,] 3.770886 4.057238
#> [13,] 4.172152 4.385894
#> [14,] 4.015823 4.345643
#> [15,] 4.168354 3.871123
#> [16,] 4.332911 4.224151
#> GCATGTATCAAACCGT-300.1.1 GCGACCAAGAGCCTAG-300.1.1
#> [1,] 4.070641 4.645789
#> [2,] 4.479960 3.733684
#> [3,] 4.739479 4.202105
#> [4,] 4.270040 4.330000
#> [5,] 4.617735 4.491579
#> [6,] 4.225952 4.120526
#> [7,] 4.119739 4.437368
#> [8,] 4.524048 4.515789
#> [9,] 4.474449 4.053158
#> [10,] 4.278056 3.762105
#> [11,] 4.141784 4.213158
#> [12,] 4.284569 4.052632
#> [13,] 4.515531 4.227368
#> [14,] 4.119739 3.996842
#> [15,] 4.084168 3.923684
#> [16,] 4.539579 4.092105
#> GCGAGAAAGCCGTCGT-300.1.1 GCTCCTACAGCCAATT-300.1.1
#> [1,] 4.356305 4.402330
#> [2,] 4.199314 4.056452
#> [3,] 4.357449 4.121864
#> [4,] 4.106663 4.256272
#> [5,] 5.076923 5.196237
#> [6,] 4.110666 4.550179
#> [7,] 4.926794 4.592294
#> [8,] 4.374607 4.242832
#> [9,] 4.211610 4.192652
#> [10,] 4.020017 4.163978
#> [11,] 4.321418 4.279570
#> [12,] 4.213898 4.221326
#> [13,] 4.304547 4.256272
#> [14,] 4.258507 3.956989
#> [15,] 4.150701 3.989247
#> [16,] 4.447526 4.201613
#> GCTGCGAAGTCAAGGC-300.1.1 GCTGCGATCTATCCCG-300.1.1
#> [1,] 4.9512 4.733987
#> [2,] 4.0072 3.633583
#> [3,] 4.5472 3.799192
#> [4,] 4.5432 3.978073
#> [5,] 5.1008 5.371610
#> [6,] 3.9304 3.819388
#> [7,] 4.9688 4.855741
#> [8,] 3.9888 4.227351
#> [9,] 4.1144 3.940565
#> [10,] 3.8704 3.552799
#> [11,] 3.9432 4.084824
#> [12,] 4.3856 3.735718
#> [13,] 4.5704 4.215234
#> [14,] 3.9384 4.316215
#> [15,] 3.8840 3.870744
#> [16,] 4.0800 4.508367
#> GCTGGGTAGGACACCA-300.1.1 GCTTGAACAAGCCATT-300.1.1
#> [1,] 4.618265 4.296247
#> [2,] 3.731507 3.920912
#> [3,] 4.099543 4.323503
#> [4,] 3.877626 4.352994
#> [5,] 5.202740 4.688561
#> [6,] 3.978995 4.227435
#> [7,] 4.789041 4.516533
#> [8,] 4.192694 4.499553
#> [9,] 3.919635 4.432529
#> [10,] 3.684932 4.061215
#> [11,] 3.969863 4.274799
#> [12,] 4.153425 4.247989
#> [13,] 4.125114 4.088025
#> [14,] 4.119635 4.200626
#> [15,] 4.174429 3.972297
#> [16,] 4.568950 4.216711
#> GCTTGAACAGATGGGT-300.1.1 GGACAGAAGGCATGTG-300.1.1
#> [1,] 4.465588 4.731670
#> [2,] 4.190882 3.953893
#> [3,] 4.163235 3.888133
#> [4,] 4.226471 4.468632
#> [5,] 4.823824 5.047619
#> [6,] 3.828529 4.041572
#> [7,] 4.565294 4.902494
#> [8,] 4.260588 4.156463
#> [9,] 4.122647 4.269841
#> [10,] 3.954706 3.790627
#> [11,] 4.378824 4.124717
#> [12,] 4.015000 4.040060
#> [13,] 4.187941 4.203326
#> [14,] 4.384412 4.505669
#> [15,] 4.056471 3.846561
#> [16,] 4.206176 3.833711
#> GGAGCAATCGTTTAGG-300.1.1 GGATGTTCACTTCTGC-300.1.1
#> [1,] 4.286765 4.424522
#> [2,] 3.659926 4.142945
#> [3,] 4.100184 4.179298
#> [4,] 4.240809 4.510783
#> [5,] 4.891544 4.565003
#> [6,] 3.770221 4.012323
#> [7,] 4.811581 4.440542
#> [8,] 4.100184 4.573013
#> [9,] 4.062500 4.190388
#> [10,] 4.064338 4.053604
#> [11,] 3.992647 3.961799
#> [12,] 3.876838 4.202095
#> [13,] 4.141544 4.284658
#> [14,] 4.015625 4.049291
#> [15,] 3.694853 4.265558
#> [16,] 4.453125 4.260628
#> GGATTACAGCCAGTAG-300.1.1 GGCGACTAGACGACGT-300.1.1
#> [1,] 4.310802 4.459818
#> [2,] 4.266582 3.832285
#> [3,] 4.312066 3.772886
#> [4,] 4.276058 4.519916
#> [5,] 4.476311 4.837876
#> [6,] 4.071383 3.832285
#> [7,] 4.301958 4.967855
#> [8,] 4.409349 4.153739
#> [9,] 4.236260 4.026555
#> [10,] 3.760581 3.843466
#> [11,] 3.986734 3.966457
#> [12,] 3.905875 3.943396
#> [13,] 4.437145 4.332635
#> [14,] 4.146557 4.187282
#> [15,] 3.975995 3.788959
#> [16,] 4.734681 4.052411
#> GGCTCGACACACAGAG-300.1.1 GGCTCGATCATCATTC-300.1.1
#> [1,] 4.369041 4.661405
#> [2,] 3.845205 4.084451
#> [3,] 4.186203 3.652723
#> [4,] 4.201346 3.911602
#> [5,] 5.132922 5.102605
#> [6,] 4.142457 3.631413
#> [7,] 4.600673 4.556433
#> [8,] 4.080763 4.636148
#> [9,] 4.185081 3.981847
#> [10,] 3.893999 3.584846
#> [11,] 4.196298 4.224941
#> [12,] 4.146383 3.793212
#> [13,] 4.138531 3.826361
#> [14,] 4.293887 4.749803
#> [15,] 3.901290 3.581689
#> [16,] 4.438587 4.280979
#> GGGACCTCACCGAAAG-300.1.1 GGGACCTGTCTACCTC-300.1.1
#> [1,] 4.703304 4.463087
#> [2,] 3.835469 3.917633
#> [3,] 3.949427 4.023185
#> [4,] 4.070802 4.336181
#> [5,] 5.440998 4.837706
#> [6,] 3.832771 4.167175
#> [7,] 4.927175 4.440513
#> [8,] 4.268375 4.230628
#> [9,] 3.951450 4.101281
#> [10,] 3.879973 3.870043
#> [11,] 4.003372 4.225747
#> [12,] 4.020904 3.973764
#> [13,] 4.078894 4.323978
#> [14,] 4.327714 4.338621
#> [15,] 3.946730 4.010372
#> [16,] 4.213082 4.672361
#> GGGATGACAGCTCGCA-300.1.1 GGGCATCCATACTACG-300.1.1
#> [1,] 4.160137 4.706515
#> [2,] 4.074678 4.094244
#> [3,] 4.276887 4.191018
#> [4,] 4.333421 4.392789
#> [5,] 4.978438 4.716003
#> [6,] 4.190902 3.939911
#> [7,] 4.966342 4.516129
#> [8,] 4.392585 4.669197
#> [9,] 4.429924 4.349779
#> [10,] 4.190902 4.293485
#> [11,] 4.235866 4.433903
#> [12,] 4.180121 4.103099
#> [13,] 4.245333 4.182163
#> [14,] 4.433605 4.403542
#> [15,] 3.954773 3.865275
#> [16,] 4.201420 4.454143
#> GGGTTGCAGCCCAACC-300.1.1 GGGTTGCTCCTTTACA-300.1.1
#> [1,] 4.032999 4.794551
#> [2,] 4.339670 4.243004
#> [3,] 4.292324 4.346097
#> [4,] 4.317432 4.491163
#> [5,] 4.647776 4.582474
#> [6,] 4.386298 3.934462
#> [7,] 4.613343 4.074374
#> [8,] 4.532640 4.663476
#> [9,] 4.408895 3.961708
#> [10,] 4.251793 3.995582
#> [11,] 4.368006 4.337261
#> [12,] 3.896341 4.016200
#> [13,] 4.308824 4.171576
#> [14,] 4.333214 3.778351
#> [15,] 3.887733 4.441090
#> [16,] 4.310617 4.484536
#> GGTATTGAGAGTTGGC-300.1.1 GGTATTGAGTCATCCA-300.1.1
#> [1,] 4.552463 4.764212
#> [2,] 3.755353 3.770672
#> [3,] 3.960385 4.155039
#> [4,] 4.282655 4.161499
#> [5,] 4.922377 5.242894
#> [6,] 3.880086 3.645995
#> [7,] 4.803533 4.971576
#> [8,] 4.288544 4.140827
#> [9,] 3.958779 4.029716
#> [10,] 4.062099 3.725452
#> [11,] 3.943255 4.193152
#> [12,] 4.034797 3.888889
#> [13,] 4.185225 4.250000
#> [14,] 4.281049 4.239018
#> [15,] 4.157923 3.960594
#> [16,] 4.330300 4.501292
#> GGTGAAGAGAAACCGC-300.1.1 GGTGAAGGTCCATGAT-300.1.1
#> [1,] 4.491661 4.586309
#> [2,] 4.428286 3.516868
#> [3,] 4.393596 4.009111
#> [4,] 4.409606 4.227284
#> [5,] 4.707138 5.000000
#> [6,] 3.838559 3.869737
#> [7,] 3.976651 4.963063
#> [8,] 4.855237 4.211524
#> [9,] 4.088726 4.085939
#> [10,] 4.076051 3.792416
#> [11,] 4.130754 3.764098
#> [12,] 3.955304 4.086924
#> [13,] 4.134089 4.320118
#> [14,] 4.040027 4.276040
#> [15,] 4.196131 4.014775
#> [16,] 4.445630 4.065747
#> GGTGAAGTCATAAAGG-300.1.1 GGTGAAGTCGCAGGCT-300.1.1
#> [1,] 4.595608 4.272336
#> [2,] 4.230558 4.026911
#> [3,] 4.225069 4.287047
#> [4,] 4.385178 4.152494
#> [5,] 4.182983 5.154647
#> [6,] 4.452882 3.979548
#> [7,] 4.599268 5.128812
#> [8,] 5.057640 4.297094
#> [9,] 4.495883 4.230355
#> [10,] 4.252516 4.077144
#> [11,] 4.364135 4.365267
#> [12,] 4.586459 4.033010
#> [13,] 4.373285 4.416577
#> [14,] 3.967978 4.525296
#> [15,] 4.166514 4.029781
#> [16,] 4.420860 4.118048
#> GTAGGCCAGCTAGCCC-300.1.1 GTAGGCCTCCTTTCTC-300.1.1
#> [1,] 4.277696 5.175767
#> [2,] 3.961765 3.287958
#> [3,] 3.804167 3.899776
#> [4,] 4.227696 4.433807
#> [5,] 5.404902 5.003740
#> [6,] 4.076225 3.926702
#> [7,] 5.067157 4.907255
#> [8,] 4.084314 4.105460
#> [9,] 3.872059 3.763650
#> [10,] 4.001961 3.851907
#> [11,] 4.092402 4.252805
#> [12,] 4.175245 4.089005
#> [13,] 4.474510 4.244577
#> [14,] 4.308824 4.069559
#> [15,] 3.673529 3.727749
#> [16,] 4.038725 3.710546
#> GTAGTCATCTGCAAGT-300.1.1 GTATTCTGTAAGGGCT-300.1.1
#> [1,] 4.505445 4.344301
#> [2,] 3.900181 4.636898
#> [3,] 4.075318 3.996475
#> [4,] 4.147005 4.091069
#> [5,] 4.594374 4.998237
#> [6,] 3.838475 3.792597
#> [7,] 4.331216 4.565217
#> [8,] 4.274047 4.601058
#> [9,] 4.156080 4.198590
#> [10,] 4.005445 3.933608
#> [11,] 3.486388 4.497062
#> [12,] 4.603448 3.827262
#> [13,] 4.235935 4.145123
#> [14,] 4.310345 4.904818
#> [15,] 4.101633 3.817274
#> [16,] 4.425590 4.047004
#> GTCTCGTTCTTCTGGC-300.1.1 GTGCAGCGTGATGATA-300.1.1
#> [1,] 4.552898 4.251374
#> [2,] 3.601946 3.712912
#> [3,] 3.766518 3.842720
#> [4,] 4.098906 3.947802
#> [5,] 5.552493 5.802198
#> [6,] 3.966356 3.796703
#> [7,] 5.518443 5.405220
#> [8,] 4.308066 4.370192
#> [9,] 4.076611 3.932005
#> [10,] 3.779084 3.888049
#> [11,] 3.823267 4.062500
#> [12,] 3.945278 3.792582
#> [13,] 4.155249 4.216346
#> [14,] 4.455209 4.412088
#> [15,] 3.677746 3.760989
#> [16,] 3.969193 4.019918
#> GTGCAGCTCAGCTCTC-300.1.1 GTGCATATCGTCCGTT-300.1.1
#> [1,] 4.510772 4.182022
#> [2,] 3.929059 3.706805
#> [3,] 3.965843 4.044805
#> [4,] 4.063058 4.063848
#> [5,] 5.105623 5.203024
#> [6,] 3.841829 4.064968
#> [7,] 4.913295 5.091851
#> [8,] 4.248555 4.257631
#> [9,] 4.233841 4.004761
#> [10,] 4.036784 3.944553
#> [11,] 4.303205 4.147298
#> [12,] 4.266947 3.840381
#> [13,] 4.231214 4.147578
#> [14,] 4.202838 4.487539
#> [15,] 4.050972 3.865584
#> [16,] 4.473988 3.958275
#> GTGCGGTGTAAATGTG-300.1.1 GTGTTAGAGAGCCCAA-300.1.1
#> [1,] 4.406426 4.868345
#> [2,] 3.668273 3.571942
#> [3,] 4.007229 3.894245
#> [4,] 4.014458 4.538849
#> [5,] 5.527711 5.155396
#> [6,] 3.859438 3.729496
#> [7,] 5.078715 4.422302
#> [8,] 4.200000 4.410791
#> [9,] 3.951004 4.186331
#> [10,] 3.795181 3.615827
#> [11,] 4.104418 3.668345
#> [12,] 3.869076 4.217986
#> [13,] 4.076305 4.206475
#> [14,] 4.064257 4.192086
#> [15,] 4.159036 3.949640
#> [16,] 4.186345 3.835252
#> GTTACAGAGCTAAGAT-300.1.1 GTTCTCGGTCGCCATG-300.1.1
#> [1,] 4.609157 4.727664
#> [2,] 3.577889 4.120560
#> [3,] 3.864880 3.972013
#> [4,] 3.820771 4.038751
#> [5,] 4.917365 4.998385
#> [6,] 3.797878 4.023143
#> [7,] 4.857621 4.422497
#> [8,] 4.195980 4.409580
#> [9,] 4.348409 4.141012
#> [10,] 3.829146 3.708288
#> [11,] 4.256281 4.036598
#> [12,] 4.302624 3.853068
#> [13,] 4.367951 4.261033
#> [14,] 4.412619 4.261572
#> [15,] 3.742602 3.890205
#> [16,] 4.082635 4.501615
#> TACACGAAGTCCTCCT-300.1.1 TACCTATAGTGAAGAG-300.1.1
#> [1,] 4.523778 4.523353
#> [2,] 3.553918 4.169546
#> [3,] 3.908238 4.340371
#> [4,] 4.394508 4.028151
#> [5,] 5.022103 4.543826
#> [6,] 3.915606 4.059501
#> [7,] 4.882117 4.253359
#> [8,] 4.320831 4.621241
#> [9,] 3.957133 4.223289
#> [10,] 3.780978 4.007678
#> [11,] 3.995311 4.062060
#> [12,] 4.001340 4.077415
#> [13,] 4.027461 4.367242
#> [14,] 4.534494 4.095969
#> [15,] 3.884126 4.229047
#> [16,] 3.896852 4.474728
#> TACCTATAGTGTGAAT-300.1.1 TACTTGTTCGCTAGCG-300.1.1
#> [1,] 4.365613 4.334379
#> [2,] 4.323123 3.922836
#> [3,] 4.225296 3.983689
#> [4,] 4.280632 4.130489
#> [5,] 4.310277 5.262233
#> [6,] 4.663043 4.037641
#> [7,] 4.739130 4.784818
#> [8,] 4.876482 4.490590
#> [9,] 4.416008 3.907152
#> [10,] 4.369565 4.003137
#> [11,] 4.346838 4.200753
#> [12,] 4.281621 4.027604
#> [13,] 4.431818 4.087829
#> [14,] 4.090909 4.231493
#> [15,] 4.161067 3.990590
#> [16,] 4.565217 4.564617
#> TAGCCGGAGCCCAATT-300.1.1 TATCTCAGTTTAAGCC-300.1.1
#> [1,] 4.637358 4.488246
#> [2,] 3.538088 4.347197
#> [3,] 3.942464 4.185353
#> [4,] 4.116288 3.954792
#> [5,] 4.899514 4.667269
#> [6,] 4.089546 4.508137
#> [7,] 4.837925 3.965642
#> [8,] 4.125608 4.459313
#> [9,] 4.102512 4.108499
#> [10,] 3.748784 3.991863
#> [11,] 4.299838 3.811935
#> [12,] 4.391005 4.259494
#> [13,] 4.243922 4.372514
#> [14,] 4.081037 4.287523
#> [15,] 3.895057 4.145570
#> [16,] 3.725284 5.027125
#> TATGCCCCAATAGCGG-300.1.1 TATTACCCAGGCTGAA-300.1.1
#> [1,] 4.274821 4.667969
#> [2,] 4.205719 4.529297
#> [3,] 4.250199 4.370117
#> [4,] 4.120731 4.352539
#> [5,] 4.408261 4.534180
#> [6,] 4.346307 4.474609
#> [7,] 4.402701 4.662109
#> [8,] 4.782367 4.622070
#> [9,] 4.772836 4.737305
#> [10,] 4.122319 4.256836
#> [11,] 4.424940 4.303711
#> [12,] 4.713264 4.712891
#> [13,] 4.565528 4.183594
#> [14,] 4.249404 4.274414
#> [15,] 4.113582 4.236328
#> [16,] 4.471803 4.509766
#> TATTACCTCCATGCTC-300.1.1 TCAATCTAGAGCTATA-300.1.1
#> [1,] 4.416588 4.600943
#> [2,] 4.207352 4.342105
#> [3,] 4.186616 4.325609
#> [4,] 4.678605 4.408484
#> [5,] 4.224317 4.461508
#> [6,] 4.101791 4.379811
#> [7,] 4.416588 4.322859
#> [8,] 4.903864 4.742341
#> [9,] 4.401508 4.778083
#> [10,] 4.229029 4.359780
#> [11,] 4.451461 4.232914
#> [12,] 4.254477 4.482325
#> [13,] 4.343073 4.467007
#> [14,] 4.265787 4.175177
#> [15,] 4.182846 4.397486
#> [16,] 4.757776 4.546740
#> TCAATCTAGGTGCACA-300.1.1 TCACGAATCGATGAGG-300.1.1
#> [1,] 4.387485 4.273940
#> [2,] 3.853884 4.304553
#> [3,] 4.215475 4.420722
#> [4,] 3.847719 4.399529
#> [5,] 5.009248 4.481947
#> [6,] 4.133785 3.759027
#> [7,] 5.017263 4.561224
#> [8,] 4.248150 4.518053
#> [9,] 4.135018 4.459969
#> [10,] 3.999692 4.445055
#> [11,] 4.369914 4.474097
#> [12,] 4.344020 4.723705
#> [13,] 4.449445 4.458399
#> [14,] 4.334464 4.114600
#> [15,] 3.985512 4.259027
#> [16,] 4.127312 4.291209
#> TCAGGTAAGTACGTAA-300.1.1 TCATTACAGCAACGGT-300.1.1
#> [1,] 4.584323 4.594980
#> [2,] 3.732185 3.799201
#> [3,] 3.954869 4.045636
#> [4,] 4.229810 4.359954
#> [5,] 5.198931 4.616657
#> [6,] 4.124109 4.227610
#> [7,] 4.796318 4.518540
#> [8,] 4.212589 4.418140
#> [9,] 3.990499 4.178551
#> [10,] 3.902613 3.897319
#> [11,] 4.100356 4.383343
#> [12,] 4.084917 4.227610
#> [13,] 4.112827 4.289789
#> [14,] 4.451306 4.128922
#> [15,] 4.034442 3.905305
#> [16,] 4.359264 3.961780
#> TCCACACGTGTAACGG-300.1.1 TCCCGATCACCAACCG-300.1.1
#> [1,] 4.853867 4.645985
#> [2,] 3.267733 3.953076
#> [3,] 3.730667 3.944213
#> [4,] 4.139733 3.879041
#> [5,] 5.317333 5.516163
#> [6,] 3.835733 3.976017
#> [7,] 4.821867 4.557873
#> [8,] 4.026133 4.145985
#> [9,] 4.034667 3.770073
#> [10,] 3.794133 3.781543
#> [11,] 3.942933 4.054745
#> [12,] 3.819200 4.090198
#> [13,] 4.025067 4.038582
#> [14,] 4.504000 4.188738
#> [15,] 3.868800 4.027112
#> [16,] 4.144000 4.745568
#> TCGAGGCAGGAGTACC-300.1.1 TCGGGACAGTGGAGAA-300.1.1
#> [1,] 4.934377 4.744471
#> [2,] 3.367851 3.705259
#> [3,] 3.828417 4.212414
#> [4,] 4.180614 4.315555
#> [5,] 5.478627 4.972682
#> [6,] 3.734497 3.974168
#> [7,] 5.382902 4.736666
#> [8,] 3.978928 4.188998
#> [9,] 3.974112 4.057796
#> [10,] 3.604455 3.890169
#> [11,] 4.060205 4.244750
#> [12,] 3.957255 4.097008
#> [13,] 4.152920 4.180078
#> [14,] 4.283564 4.028991
#> [15,] 4.056592 3.979929
#> [16,] 4.367851 4.193273
#> TCGTAGAGTAGCGCTC-300.1.1 TCTCATAAGCGATCCC-300.1.1
#> [1,] 4.648009 4.122483
#> [2,] 3.791114 4.525168
#> [3,] 4.111945 4.373322
#> [4,] 4.258511 4.270134
#> [5,] 4.994807 4.255034
#> [6,] 4.002885 4.192953
#> [7,] 4.985574 4.058725
#> [8,] 4.302366 4.876678
#> [9,] 4.329486 4.809564
#> [10,] 4.249279 4.408557
#> [11,] 4.285632 4.054530
#> [12,] 4.049625 4.553691
#> [13,] 4.137334 4.229027
#> [14,] 4.339296 4.357383
#> [15,] 3.938257 4.256711
#> [16,] 3.878246 4.819631
#> TCTCATACAAGGTGTG-300.1.1 TCTGGAATCTTCGAGA-300.1.1
#> [1,] 4.829936 4.781009
#> [2,] 3.526752 3.509199
#> [3,] 3.925478 4.157270
#> [4,] 4.328025 4.328190
#> [5,] 5.222293 4.727596
#> [6,] 3.646497 4.064688
#> [7,] 5.004459 4.632641
#> [8,] 4.287898 4.411276
#> [9,] 4.001274 4.063501
#> [10,] 3.617834 3.905045
#> [11,] 3.907643 4.456380
#> [12,] 4.019745 4.166766
#> [13,] 4.113376 4.329970
#> [14,] 4.166242 4.184570
#> [15,] 3.985987 4.011276
#> [16,] 4.263694 3.960237
#> TCTTCGGAGACAAGCC-300.1.1 TCTTCGGAGCCCTAAT-300.1.1
#> [1,] 4.052893 4.868140
#> [2,] 4.073719 3.690663
#> [3,] 4.308099 4.074127
#> [4,] 4.138512 4.632929
#> [5,] 4.857521 4.760513
#> [6,] 4.312397 3.875980
#> [7,] 4.827769 4.118318
#> [8,] 4.520331 4.397719
#> [9,] 4.276694 4.198860
#> [10,] 4.269091 4.163222
#> [11,] 4.325620 4.146115
#> [12,] 4.252562 4.129722
#> [13,] 4.388430 3.865289
#> [14,] 4.231405 4.069850
#> [15,] 4.010579 4.337847
#> [16,] 4.433058 4.129009
#> TGAAAGAAGGTGCACA-300.1.1 TGACAACCAATGAATG-300.1.1
#> [1,] 4.569661 4.296023
#> [2,] 4.112080 3.920455
#> [3,] 4.153476 4.095455
#> [4,] 4.178225 4.018750
#> [5,] 4.705154 4.790909
#> [6,] 3.945251 3.956818
#> [7,] 4.326627 4.535795
#> [8,] 4.542687 4.553409
#> [9,] 4.203240 4.234091
#> [10,] 4.009169 4.006250
#> [11,] 4.189175 3.739205
#> [12,] 4.039526 4.455682
#> [13,] 4.391347 4.157386
#> [14,] 4.152408 4.290341
#> [15,] 3.946141 3.952841
#> [16,] 4.271610 4.450000
#> TGAGCCGGTCTCTTTA-300.1.1 TGCACCTAGAGGTAGA-300.1.1
#> [1,] 4.643202 5.033312
#> [2,] 3.474810 3.502242
#> [3,] 3.836439 3.641896
#> [4,] 3.775707 4.147982
#> [5,] 5.386473 5.579757
#> [6,] 3.900621 3.738629
#> [7,] 5.052450 4.977578
#> [8,] 4.264320 4.005125
#> [9,] 4.041408 3.943626
#> [10,] 3.728778 3.594491
#> [11,] 4.198758 4.021140
#> [12,] 3.978606 3.997438
#> [13,] 4.309869 4.253684
#> [14,] 4.358868 4.142857
#> [15,] 4.026915 4.002562
#> [16,] 4.585231 4.545804
#> TGCCCATAGGGCTTGA-300.1.1 TGCCCATGTCAATGTC-300.1.1
#> [1,] 4.355194 4.560647
#> [2,] 3.825289 4.212264
#> [3,] 3.866212 4.423181
#> [4,] 4.270199 4.336927
#> [5,] 5.335782 4.485175
#> [6,] 3.784890 4.741914
#> [7,] 5.255509 4.519542
#> [8,] 4.113851 4.863208
#> [9,] 4.047219 4.508086
#> [10,] 3.849948 4.496631
#> [11,] 4.191501 4.867925
#> [12,] 4.267576 4.291105
#> [13,] 4.290661 4.059299
#> [14,] 4.083421 4.266173
#> [15,] 3.849423 4.167116
#> [16,] 3.938090 4.679919
#> TGCCCTATCAGGTTCA-300.1.1 TGCGGGTTCATTGCGA-300.1.1
#> [1,] 4.965079 4.552885
#> [2,] 3.871746 3.814904
#> [3,] 3.793016 3.942308
#> [4,] 4.184762 4.234976
#> [5,] 5.326349 4.549880
#> [6,] 3.972063 4.062500
#> [7,] 4.739048 4.307692
#> [8,] 4.189841 4.524038
#> [9,] 4.150476 4.034856
#> [10,] 4.078095 4.041466
#> [11,] 4.379683 3.972356
#> [12,] 3.746032 3.966947
#> [13,] 4.095873 4.498798
#> [14,] 4.060317 3.912260
#> [15,] 4.144127 3.965144
#> [16,] 4.291429 4.293870
#> TGCGTGGAGCAGCGTA-300.1.1 TGCTACCAGGCGATAC-300.1.1
#> [1,] 4.095532 4.411005
#> [2,] 4.318952 4.000957
#> [3,] 4.088598 4.304306
#> [4,] 3.952234 4.336364
#> [5,] 4.588598 4.990431
#> [6,] 4.567026 3.971292
#> [7,] 4.194145 5.072249
#> [8,] 4.567797 4.362679
#> [9,] 4.399846 4.339234
#> [10,] 4.497689 3.889474
#> [11,] 4.106317 3.939234
#> [12,] 4.246533 4.150239
#> [13,] 4.656394 4.254545
#> [14,] 4.101695 4.290431
#> [15,] 3.907550 3.727751
#> [16,] 4.915254 4.136364
#> TGGCTGGAGTCCATAC-300.1.1 TGGTTAGTCTGCCAGG-300.1.1
#> [1,] 4.646641 4.614709
#> [2,] 3.777778 3.767289
#> [3,] 3.809432 3.908342
#> [4,] 4.025194 4.333699
#> [5,] 5.519380 4.935236
#> [6,] 4.040052 3.958836
#> [7,] 4.965762 4.516465
#> [8,] 4.076873 4.309550
#> [9,] 4.054910 3.982986
#> [10,] 3.961886 3.962678
#> [11,] 4.198320 3.853458
#> [12,] 3.991602 4.198683
#> [13,] 4.208010 4.075741
#> [14,] 4.337209 4.261251
#> [15,] 3.867571 4.185510
#> [16,] 4.414083 4.267289
#> TGGTTCCTCGTTACGA-300.1.1 TGTGGTATCTGCTTGC-300.1.1
#> [1,] 4.528892 4.336290
#> [2,] 4.006486 3.729490
#> [3,] 4.089623 3.968219
#> [4,] 4.235849 4.471545
#> [5,] 5.127948 4.957132
#> [6,] 3.867335 3.988174
#> [7,] 4.780071 5.047302
#> [8,] 4.225236 4.115299
#> [9,] 4.086085 4.060606
#> [10,] 3.890330 3.999261
#> [11,] 4.050708 4.302291
#> [12,] 4.041274 3.778271
#> [13,] 4.191627 4.276423
#> [14,] 4.216981 4.048780
#> [15,] 3.870283 3.682188
#> [16,] 4.133844 3.898004
#> TTAACTCAGTACACCT-300.1.1 TTAACTCCATCGGTTA-300.1.1
#> [1,] 4.349562 4.587451
#> [2,] 4.265823 3.419960
#> [3,] 4.445959 3.751976
#> [4,] 3.962999 4.193182
#> [5,] 4.443038 5.139328
#> [6,] 4.487829 3.939723
#> [7,] 4.353457 5.006423
#> [8,] 4.478092 4.013340
#> [9,] 4.645570 4.132411
#> [10,] 4.214216 3.646739
#> [11,] 4.297955 3.974802
#> [12,] 4.274586 4.147233
#> [13,] 4.702045 4.211462
#> [14,] 4.120740 4.439229
#> [15,] 4.154820 3.495553
#> [16,] 4.358325 4.015316
#> TTAGGACGTCATCGGC-300.1.1 TTATGCTAGCCGGTAA-300.1.1
#> [1,] 4.669474 5.127704
#> [2,] 3.758947 3.834613
#> [3,] 4.031053 3.884857
#> [4,] 4.032105 3.678995
#> [5,] 5.370000 5.314724
#> [6,] 3.658947 3.876483
#> [7,] 4.720000 4.158409
#> [8,] 4.172632 4.645499
#> [9,] 4.005263 3.836008
#> [10,] 3.505263 3.887648
#> [11,] 4.076316 4.016748
#> [12,] 4.058421 3.739009
#> [13,] 4.120000 4.349616
#> [14,] 4.531053 4.147941
#> [15,] 3.847895 4.205862
#> [16,] 4.660526 4.950454
#> TTATGCTCATGCCCGA-300.1.1 TTATGCTTCAACGGCC-300.1.1
#> [1,] 4.445450 4.538008
#> [2,] 3.864697 3.888927
#> [3,] 3.868985 4.063867
#> [4,] 4.224393 4.314127
#> [5,] 5.044307 4.879556
#> [6,] 4.051929 4.202707
#> [7,] 4.797046 4.667129
#> [8,] 4.276798 4.198195
#> [9,] 4.130062 4.105519
#> [10,] 3.923297 4.027074
#> [11,] 3.921391 3.984033
#> [12,] 4.226298 4.300590
#> [13,] 4.228204 4.517876
#> [14,] 4.363506 4.217286
#> [15,] 3.925202 3.866019
#> [16,] 4.078609 4.137105
#> TTCGGTCTCGGCTTGG-300.1.1 TTCTACAAGTCGAGTG-300.1.1
#> [1,] 4.801986 4.783711
#> [2,] 3.349883 3.780475
#> [3,] 4.032126 3.943366
#> [4,] 4.336449 4.290723
#> [5,] 5.397196 5.127832
#> [6,] 3.761098 3.971413
#> [7,] 5.080023 4.638619
#> [8,] 4.199766 4.462244
#> [9,] 3.946262 3.871090
#> [10,] 3.912383 3.845739
#> [11,] 4.228388 4.095469
#> [12,] 4.035631 3.942287
#> [13,] 4.053738 4.090076
#> [14,] 4.214369 3.995685
#> [15,] 4.117991 3.981661
#> [16,] 4.231308 4.554477
#> TTCTCAATCGCACTCT-300.1.1 TTCTTAGCAAACAACA-300.1.1
#> [1,] 4.679194 4.418746
#> [2,] 4.169390 4.016183
#> [3,] 4.125272 4.013486
#> [4,] 4.146514 4.259609
#> [5,] 5.053377 4.683749
#> [6,] 4.053377 3.990560
#> [7,] 4.077342 4.304788
#> [8,] 4.626906 4.476062
#> [9,] 3.890523 4.118004
#> [10,] 3.984205 3.919757
#> [11,] 4.062092 4.180715
#> [12,] 3.986383 4.279838
#> [13,] 4.279956 3.998651
#> [14,] 4.099129 4.280512
#> [15,] 4.125272 4.020229
#> [16,] 4.801198 4.188806
#> TTCTTAGTCACGCGGT-300.1.1 TTCTTAGTCCAAGTAC-300.1.1
#> [1,] 4.866798 4.371795
#> [2,] 3.996719 3.941026
#> [3,] 3.999344 4.121538
#> [4,] 4.135827 4.213333
#> [5,] 4.958005 4.956410
#> [6,] 3.881234 3.803590
#> [7,] 4.397638 4.807692
#> [8,] 4.374016 4.261026
#> [9,] 4.169291 3.960513
#> [10,] 3.932415 3.894872
#> [11,] 4.116142 3.996410
#> [12,] 4.015748 3.892308
#> [13,] 4.258530 4.396410
#> [14,] 3.982940 4.212308
#> [15,] 4.043307 4.096410
#> [16,] 4.749344 4.200000
#> TTGAACGAGAAACCTA-300.1.1 TTGCCGTGTAAGCACG-300.1.1
#> [1,] 4.441058 4.409427
#> [2,] 3.751681 3.699630
#> [3,] 3.868221 3.916513
#> [4,] 4.381443 4.334258
#> [5,] 4.870462 4.961491
#> [6,] 3.745406 4.075786
#> [7,] 4.926042 4.996611
#> [8,] 4.258180 4.124769
#> [9,] 4.233976 4.098275
#> [10,] 3.917974 4.040049
#> [11,] 4.122815 4.296981
#> [12,] 3.800986 3.853666
#> [13,] 4.308830 4.206100
#> [14,] 4.480502 4.372458
#> [15,] 3.658449 3.789279
#> [16,] 4.059615 4.023413
#> TTGGAACCAGATCGGA-300.1.1 AAACCTGGTTCCAACA-300.1.2
#> [1,] 4.376353 4.294349
#> [2,] 4.035513 3.938374
#> [3,] 4.439584 4.268557
#> [4,] 4.299697 4.208506
#> [5,] 4.850585 5.022445
#> [6,] 4.138588 3.921638
#> [7,] 4.790819 4.752707
#> [8,] 4.414465 4.529632
#> [9,] 4.341273 4.037409
#> [10,] 4.184062 3.922623
#> [11,] 4.268081 4.105336
#> [12,] 4.442616 4.099232
#> [13,] 4.372456 4.245718
#> [14,] 4.081854 4.161449
#> [15,] 4.269814 3.982477
#> [16,] 4.574708 4.097066
#> AAAGATGTCGATAGAA-300.1.2 AACACGTAGATCCCAT-300.1.2
#> [1,] 4.304414 4.269475
#> [2,] 4.247083 3.776042
#> [3,] 3.827499 3.963768
#> [4,] 3.848300 4.177989
#> [5,] 4.981228 5.338089
#> [6,] 3.752917 4.237319
#> [7,] 4.652968 5.262002
#> [8,] 4.758498 4.451993
#> [9,] 4.270421 4.109828
#> [10,] 3.778792 3.990036
#> [11,] 4.396753 4.108922
#> [12,] 3.822933 3.990489
#> [13,] 4.057331 4.100317
#> [14,] 4.705733 4.288949
#> [15,] 3.791984 3.746377
#> [16,] 4.199899 4.089674
#> AACGTTGGTATTAGCC-300.1.2 AACTCTTAGGCCCTCA-300.1.2
#> [1,] 4.565676 4.604981
#> [2,] 4.502397 3.671103
#> [3,] 4.163950 3.722198
#> [4,] 4.380633 3.960069
#> [5,] 4.375839 5.087162
#> [6,] 3.912752 3.968656
#> [7,] 4.247363 4.937312
#> [8,] 4.850431 4.037355
#> [9,] 4.391179 4.188493
#> [10,] 4.098754 3.708029
#> [11,] 4.157239 4.189781
#> [12,] 4.210930 3.858308
#> [13,] 4.804410 4.068699
#> [14,] 3.979866 4.217690
#> [15,] 4.070949 3.638901
#> [16,] 4.175455 4.075140
#> AACTCTTGTACAGCAG-300.1.2 AACTCTTGTGGCGAAT-300.1.2
#> [1,] 4.256364 4.357417
#> [2,] 4.604545 3.529412
#> [3,] 3.954545 3.898977
#> [4,] 4.191818 4.173274
#> [5,] 4.780000 5.597187
#> [6,] 3.900909 3.984655
#> [7,] 4.714545 5.267903
#> [8,] 4.907273 4.092711
#> [9,] 3.874545 4.256394
#> [10,] 3.930000 3.891944
#> [11,] 4.390000 4.070972
#> [12,] 3.909091 3.958440
#> [13,] 3.974545 4.131714
#> [14,] 5.009091 4.053069
#> [15,] 3.757273 3.923913
#> [16,] 4.185455 3.927110
#> AACTGGTAGTCTTGCA-300.1.2 AACTTTCCAAGGCTCC-300.1.2
#> [1,] 4.720575 4.263999
#> [2,] 3.707547 3.975426
#> [3,] 4.129380 4.076005
#> [4,] 4.291554 4.305248
#> [5,] 5.000449 5.098648
#> [6,] 3.968553 4.167632
#> [7,] 4.876011 4.924873
#> [8,] 4.318509 4.254169
#> [9,] 4.243935 4.239951
#> [10,] 3.847260 3.995436
#> [11,] 4.111411 4.239775
#> [12,] 4.158131 4.268036
#> [13,] 4.250225 4.288924
#> [14,] 4.374663 4.266280
#> [15,] 3.835130 3.937160
#> [16,] 4.126685 4.233983
#> AAGACCTTCGCGCCAA-300.1.2 AAGCCGCCAGGTCTCG-300.1.2
#> [1,] 4.661621 4.390220
#> [2,] 3.803223 4.314371
#> [3,] 4.225586 4.202595
#> [4,] 4.239746 4.532934
#> [5,] 4.693848 4.232535
#> [6,] 4.336914 3.986028
#> [7,] 4.485840 4.127745
#> [8,] 4.366699 4.613772
#> [9,] 4.191406 4.262475
#> [10,] 4.094238 4.340319
#> [11,] 4.366211 4.082834
#> [12,] 4.074219 4.328343
#> [13,] 4.095703 4.668663
#> [14,] 4.033203 4.048902
#> [15,] 3.960938 3.935130
#> [16,] 4.322266 4.158683
#> AAGGAGCTCTTATCTG-300.1.2 AAGGCAGTCGCCTGTT-300.1.2
#> [1,] 4.885666 4.452431
#> [2,] 3.712031 3.753171
#> [3,] 3.965870 3.960888
#> [4,] 4.166809 4.237844
#> [5,] 5.404010 5.130021
#> [6,] 3.954778 3.828224
#> [7,] 4.668089 5.160677
#> [8,] 4.241468 4.412262
#> [9,] 3.969710 4.093552
#> [10,] 3.717150 3.825581
#> [11,] 4.205631 4.069767
#> [12,] 3.882253 4.051268
#> [13,] 4.018771 4.307611
#> [14,] 4.282850 4.266913
#> [15,] 4.231655 3.993658
#> [16,] 4.602389 4.206660
#> AAGGTTCGTCAAAGAT-300.1.2 AAGTCTGAGGCTAGAC-300.1.2
#> [1,] 4.568734 4.580906
#> [2,] 4.078755 3.648328
#> [3,] 4.280358 3.783711
#> [4,] 4.226598 3.902913
#> [5,] 4.826692 5.395361
#> [6,] 4.036548 3.840345
#> [7,] 4.693704 4.866235
#> [8,] 4.441170 4.152104
#> [9,] 4.190757 3.841424
#> [10,] 4.025701 3.734088
#> [11,] 4.278472 3.943366
#> [12,] 4.259373 3.951996
#> [13,] 4.180146 4.332794
#> [14,] 4.237444 4.123517
#> [15,] 4.234379 4.121359
#> [16,] 4.161754 4.165588
#> AAGTCTGGTAAGTTCC-300.1.2 ACACCCTAGTGTCTCA-300.1.2
#> [1,] 4.580906 4.261929
#> [2,] 3.913127 4.197970
#> [3,] 4.117926 4.309645
#> [4,] 4.166945 4.046701
#> [5,] 5.135891 4.606091
#> [6,] 4.082510 4.152284
#> [7,] 4.825869 4.293401
#> [8,] 4.145259 4.811168
#> [9,] 4.054023 4.587817
#> [10,] 3.925061 4.348223
#> [11,] 4.109201 4.061929
#> [12,] 4.237777 4.452792
#> [13,] 4.251251 4.724873
#> [14,] 4.215578 4.359391
#> [15,] 4.174901 4.008122
#> [16,] 4.271526 4.794924
#> ACACTGAAGGACACCA-300.1.2 ACATCAGAGCGATATA-300.1.2
#> [1,] 4.287570 4.285622
#> [2,] 4.274768 3.887306
#> [3,] 3.842115 3.987047
#> [4,] 3.919295 4.281412
#> [5,] 5.280891 5.249676
#> [6,] 3.864564 3.975065
#> [7,] 4.761596 4.853627
#> [8,] 4.474954 4.407060
#> [9,] 3.950464 4.070920
#> [10,] 3.858813 4.010687
#> [11,] 4.401670 4.174870
#> [12,] 3.945455 4.123057
#> [13,] 4.215584 4.118523
#> [14,] 4.592208 4.349741
#> [15,] 3.685343 3.863342
#> [16,] 4.246753 4.087111
#> ACATGGTAGGGTGTTG-300.1.2 ACATGGTTCACCGGGT-300.1.2
#> [1,] 4.285435 4.507378
#> [2,] 4.302053 4.088536
#> [3,] 4.062561 4.183882
#> [4,] 4.347996 4.093076
#> [5,] 5.246334 5.209989
#> [6,] 4.108504 3.823496
#> [7,] 4.763441 4.443814
#> [8,] 4.333333 4.316118
#> [9,] 4.262952 4.183882
#> [10,] 3.827957 4.009648
#> [11,] 4.210166 4.116345
#> [12,] 4.257087 4.036890
#> [13,] 4.376344 4.281498
#> [14,] 4.329423 4.157208
#> [15,] 3.962854 4.152100
#> [16,] 4.451613 4.551078
#> ACCCACTAGACTTGAA-300.1.2 ACCCACTCAGCCTGTG-300.1.2
#> [1,] 4.465294 4.419282
#> [2,] 3.847059 4.234667
#> [3,] 3.910000 4.244923
#> [4,] 4.027059 4.232615
#> [5,] 5.045294 4.452103
#> [6,] 4.037059 4.576821
#> [7,] 4.722353 4.375179
#> [8,] 4.454118 4.711179
#> [9,] 4.381765 4.534359
#> [10,] 3.664118 4.236103
#> [11,] 4.337059 4.536615
#> [12,] 3.781176 4.455590
#> [13,] 4.077059 4.298462
#> [14,] 4.392353 4.257026
#> [15,] 3.647059 4.226872
#> [16,] 4.262941 4.586462
#> ACCTTTAAGGGTCGAT-300.1.2 ACGCAGCCATGCATGT-300.1.2
#> [1,] 4.663038 4.404355
#> [2,] 3.716433 4.381725
#> [3,] 3.818559 4.309564
#> [4,] 4.059616 3.971819
#> [5,] 5.048730 4.505978
#> [6,] 4.039917 4.225021
#> [7,] 4.562468 4.214347
#> [8,] 4.262312 4.712212
#> [9,] 4.250389 4.277541
#> [10,] 3.923276 4.057643
#> [11,] 4.193883 4.091802
#> [12,] 3.939347 4.231853
#> [13,] 4.130638 4.394962
#> [14,] 4.342146 4.206661
#> [15,] 3.935718 4.217336
#> [16,] 4.327631 4.526900
#> ACGCAGCTCAGAGGTG-300.1.2 ACGGAGAGTAACGACG-300.1.2
#> [1,] 4.664358 4.308147
#> [2,] 3.815663 3.741787
#> [3,] 3.997336 4.053219
#> [4,] 4.331380 4.153745
#> [5,] 5.101225 5.042707
#> [6,] 3.953649 3.536137
#> [7,] 4.693127 4.898160
#> [8,] 4.211508 4.239816
#> [9,] 4.387320 4.569645
#> [10,] 3.864145 3.982917
#> [11,] 3.795418 4.042707
#> [12,] 4.168887 4.340342
#> [13,] 4.336708 4.660315
#> [14,] 4.207246 4.318003
#> [15,] 3.866809 3.783837
#> [16,] 4.167821 4.045992
#> ACGGGTCTCAGTGTTG-300.1.2 ACGTCAAGTGTGAATA-300.1.2
#> [1,] 4.613222 4.461050
#> [2,] 3.870061 4.059435
#> [3,] 4.302685 4.411425
#> [4,] 4.269504 4.316792
#> [5,] 5.128166 4.826313
#> [6,] 3.930851 3.837853
#> [7,] 4.766971 4.474322
#> [8,] 4.445035 4.533179
#> [9,] 4.158055 4.125216
#> [10,] 3.940983 4.015003
#> [11,] 4.252026 4.215811
#> [12,] 4.090172 3.824005
#> [13,] 4.056738 4.395268
#> [14,] 4.264691 4.159261
#> [15,] 4.060284 3.944028
#> [16,] 4.420719 4.578765
#> ACTATCTGTAGCCTCG-300.1.2 ACTGATGGTGACGGTA-300.1.2
#> [1,] 4.498657 4.135866
#> [2,] 3.933907 4.289993
#> [3,] 3.881784 4.379109
#> [4,] 4.285330 4.172389
#> [5,] 5.174637 4.105917
#> [6,] 3.848469 4.154858
#> [7,] 4.807630 4.444850
#> [8,] 4.125202 4.609934
#> [9,] 4.023643 4.413440
#> [10,] 3.796883 4.354273
#> [11,] 4.127351 4.447042
#> [12,] 3.893068 4.748722
#> [13,] 4.290167 4.443389
#> [14,] 4.257926 3.916728
#> [15,] 4.026867 4.362308
#> [16,] 4.570124 4.436815
#> ACTGATGGTTTGGCGC-300.1.2 ACTTGTTAGGCTCAGA-300.1.2
#> [1,] 4.405294 4.808290
#> [2,] 3.762353 3.736903
#> [3,] 3.956471 3.784111
#> [4,] 4.048824 4.698906
#> [5,] 4.782353 4.518135
#> [6,] 4.029412 3.925734
#> [7,] 4.816471 4.162349
#> [8,] 4.200588 4.195740
#> [9,] 4.092941 4.317214
#> [10,] 3.791765 3.850892
#> [11,] 3.745882 3.687968
#> [12,] 3.940000 4.246978
#> [13,] 4.464118 4.363846
#> [14,] 3.991765 4.309729
#> [15,] 3.899412 4.077720
#> [16,] 3.979412 3.910766
#> AGAGCTTAGTTTCCTT-300.1.2 AGAGTGGTCCCTCAGT-300.1.2
#> [1,] 4.302875 4.422745
#> [2,] 4.150160 4.149804
#> [3,] 4.034505 4.459608
#> [4,] 4.086262 4.511373
#> [5,] 4.834505 4.774902
#> [6,] 3.808946 4.109804
#> [7,] 4.513738 4.312941
#> [8,] 4.334185 4.354510
#> [9,] 4.375719 4.294902
#> [10,] 3.925879 4.150588
#> [11,] 3.741853 4.280000
#> [12,] 4.108626 4.394510
#> [13,] 4.433227 4.400784
#> [14,] 4.291374 4.228235
#> [15,] 3.908626 4.033725
#> [16,] 4.552716 4.039216
#> AGATTGCAGTCTCCTC-300.1.2 AGCGTATCACTTGGAT-300.1.2
#> [1,] 4.376820 4.221197
#> [2,] 4.252520 3.888215
#> [3,] 4.245241 3.876615
#> [4,] 4.125700 4.023464
#> [5,] 4.706047 5.261271
#> [6,] 4.219205 4.261007
#> [7,] 4.722004 5.125758
#> [8,] 4.478443 4.376219
#> [9,] 4.153695 4.052729
#> [10,] 4.289754 3.890588
#> [11,] 4.252240 4.075138
#> [12,] 4.209966 3.818613
#> [13,] 4.437850 4.161086
#> [14,] 4.257279 4.347219
#> [15,] 3.863102 3.888215
#> [16,] 4.312150 4.032955
#> AGCGTATTCCTTTCTC-300.1.2 AGCGTCGCATATGCTG-300.1.2
#> [1,] 4.460949 4.425062
#> [2,] 3.635841 4.093595
#> [3,] 3.784379 4.210510
#> [4,] 4.526593 4.303483
#> [5,] 4.790609 4.578980
#> [6,] 4.036416 4.056281
#> [7,] 5.126497 4.401741
#> [8,] 4.314806 4.587065
#> [9,] 4.112123 4.420087
#> [10,] 3.950647 4.199316
#> [11,] 4.320556 4.080535
#> [12,] 3.860565 4.349502
#> [13,] 4.251078 4.431592
#> [14,] 4.418304 4.101679
#> [15,] 3.647820 4.052550
#> [16,] 4.109727 4.719838
#> AGCTCCTTCGGGAGTA-300.1.2 AGCTCTCCAATAAGCA-300.1.2
#> [1,] 4.719341 4.562651
#> [2,] 3.851561 3.952410
#> [3,] 4.014746 4.266265
#> [4,] 4.396658 4.072892
#> [5,] 5.121406 4.683133
#> [6,] 3.959449 4.094578
#> [7,] 4.774146 4.296386
#> [8,] 4.168346 4.571687
#> [9,] 3.996805 4.290964
#> [10,] 3.851561 4.071687
#> [11,] 4.003195 4.581928
#> [12,] 3.925780 4.287349
#> [13,] 4.178914 4.242771
#> [14,] 4.055542 3.912048
#> [15,] 4.016466 3.840361
#> [16,] 4.177931 4.425904
#> AGCTCTCTCCAAGTAC-300.1.2 AGGCCACAGGCCCGTT-300.1.2
#> [1,] 4.252770 4.711856
#> [2,] 3.812474 3.892300
#> [3,] 3.819040 3.905054
#> [4,] 4.420599 4.406235
#> [5,] 5.123513 4.987246
#> [6,] 3.957325 4.136986
#> [7,] 5.287238 4.804440
#> [8,] 4.043496 4.444969
#> [9,] 4.054165 4.288144
#> [10,] 3.862536 4.180444
#> [11,] 3.900287 4.161077
#> [12,] 3.894542 3.912612
#> [13,] 4.333197 4.086915
#> [14,] 4.195732 4.276334
#> [15,] 3.632745 3.799244
#> [16,] 3.985638 3.993387
#> AGGTCATGTCGCCATG-300.1.2 AGGTCATTCAACCATG-300.1.2
#> [1,] 4.560908 4.396182
#> [2,] 3.856589 3.873203
#> [3,] 4.137320 4.006599
#> [4,] 4.472868 4.146359
#> [5,] 5.058140 4.723073
#> [6,] 4.085825 3.856941
#> [7,] 4.718715 4.781523
#> [8,] 4.230897 4.322885
#> [9,] 4.272979 4.190903
#> [10,] 4.063123 3.967004
#> [11,] 4.116279 4.107707
#> [12,] 3.998339 4.283997
#> [13,] 4.284607 4.275277
#> [14,] 4.404762 4.324770
#> [15,] 4.023256 4.031581
#> [16,] 4.101883 4.058214
#> AGTAGTCCAACACGCC-300.1.2 ATAACGCCACGAAATA-300.1.2
#> [1,] 4.574027 4.255343
#> [2,] 3.952501 4.009561
#> [3,] 4.096513 4.045557
#> [4,] 4.032340 3.952193
#> [5,] 4.688226 4.568054
#> [6,] 3.921678 3.916760
#> [7,] 4.360283 4.892576
#> [8,] 4.552804 4.365017
#> [9,] 4.580596 4.365017
#> [10,] 3.911066 4.127109
#> [11,] 4.289035 4.055681
#> [12,] 4.140475 3.979753
#> [13,] 4.748863 4.338583
#> [14,] 3.979282 4.185602
#> [15,] 3.877211 3.796963
#> [16,] 4.301668 4.307649
#> ATAAGAGCACTGTCGG-300.1.2 ATAGACCGTGACTACT-300.1.2
#> [1,] 4.584967 4.354687
#> [2,] 3.754493 4.414544
#> [3,] 4.065359 4.122929
#> [4,] 4.282680 4.147663
#> [5,] 5.006944 4.545387
#> [6,] 3.792075 4.287163
#> [7,] 4.691993 4.309671
#> [8,] 4.399918 4.755132
#> [9,] 4.285539 4.705417
#> [10,] 3.635212 4.240168
#> [11,] 4.131944 4.300767
#> [12,] 4.099673 4.613653
#> [13,] 4.127451 4.416522
#> [14,] 4.127042 4.234232
#> [15,] 4.292075 4.172397
#> [16,] 4.625000 4.519664
#> ATCATGGTCCCAAGTA-300.1.2 ATCCACCAGTCCATAC-300.1.2
#> [1,] 4.943436 4.867406
#> [2,] 3.702241 3.461173
#> [3,] 4.065635 3.939250
#> [4,] 4.114728 4.221870
#> [5,] 4.651547 5.461701
#> [6,] 4.254002 3.808769
#> [7,] 4.740662 4.852087
#> [8,] 4.450907 4.013207
#> [9,] 4.178228 3.868463
#> [10,] 3.862327 3.618595
#> [11,] 4.176628 3.896461
#> [12,] 4.185699 3.795034
#> [13,] 4.178762 3.956154
#> [14,] 4.152615 4.277866
#> [15,] 4.016542 4.020074
#> [16,] 3.937567 4.513471
#> ATCCACCAGTGGGATC-300.1.2 ATCGAGTCAGGGAGAG-300.1.2
#> [1,] 4.709501 4.576471
#> [2,] 3.740943 3.606417
#> [3,] 4.153110 4.111765
#> [4,] 4.436090 3.941176
#> [5,] 4.574846 4.547594
#> [6,] 4.120984 4.067380
#> [7,] 4.364320 4.467380
#> [8,] 4.324675 4.176471
#> [9,] 4.171565 4.358289
#> [10,] 4.132604 3.803209
#> [11,] 4.011620 4.314439
#> [12,] 4.496924 4.289305
#> [13,] 4.136022 4.213369
#> [14,] 3.997266 4.422995
#> [15,] 4.617908 3.881283
#> [16,] 4.563226 3.978075
#> ATCGAGTGTGATAAGT-300.1.2 ATGCGATCATGACGGA-300.1.2
#> [1,] 4.379088 4.444807
#> [2,] 4.007315 3.795846
#> [3,] 3.971601 4.049852
#> [4,] 4.434596 4.187537
#> [5,] 4.631670 5.317507
#> [6,] 4.228916 3.888427
#> [7,] 4.694492 5.039763
#> [8,] 4.387694 4.279228
#> [9,] 4.107573 3.985460
#> [10,] 4.085628 3.891395
#> [11,] 4.114458 3.980712
#> [12,] 4.033993 4.158457
#> [13,] 4.390275 4.233828
#> [14,] 4.182444 4.330861
#> [15,] 3.838640 4.056380
#> [16,] 4.270654 4.276261
#> ATGCGATTCTTGTATC-300.1.2 ATGGGAGGTTTGTGTG-300.1.2
#> [1,] 4.763704 4.448578
#> [2,] 3.958519 4.115974
#> [3,] 4.372593 4.142961
#> [4,] 4.038519 4.294675
#> [5,] 4.486667 5.116338
#> [6,] 3.923704 3.862509
#> [7,] 3.897037 4.983953
#> [8,] 5.195556 4.006929
#> [9,] 4.067407 4.100656
#> [10,] 4.194815 3.780088
#> [11,] 4.215556 4.021882
#> [12,] 3.985185 4.250547
#> [13,] 4.553333 4.266594
#> [14,] 4.066667 4.250182
#> [15,] 4.428148 3.940190
#> [16,] 4.471852 4.201678
#> ATTACTCTCTGTCAAG-300.1.2 ATTATCCCACAGCCCA-300.1.2
#> [1,] 4.205659 4.152584
#> [2,] 4.474810 4.160486
#> [3,] 4.146308 4.313070
#> [4,] 4.110421 4.205471
#> [5,] 4.529331 4.906991
#> [6,] 4.138716 4.200608
#> [7,] 4.349896 4.648632
#> [8,] 4.824707 4.377508
#> [9,] 4.546584 4.448024
#> [10,] 4.554175 4.156839
#> [11,] 4.113182 4.186018
#> [12,] 4.325052 4.093009
#> [13,] 4.492754 4.358055
#> [14,] 4.173223 4.316109
#> [15,] 4.023464 3.998176
#> [16,] 4.717736 4.370213
#> ATTGGACCACGCTTTC-300.1.2 CAACCAATCGTTGACA-300.1.2
#> [1,] 4.333512 4.504530
#> [2,] 3.938338 3.823311
#> [3,] 3.989276 4.043657
#> [4,] 4.353887 4.227759
#> [5,] 5.373727 5.269769
#> [6,] 4.110456 3.919687
#> [7,] 5.188204 4.981054
#> [8,] 4.372118 3.964580
#> [9,] 4.226810 4.143740
#> [10,] 3.986595 3.913509
#> [11,] 4.120107 3.986820
#> [12,] 3.846649 3.792422
#> [13,] 4.231635 4.436573
#> [14,] 4.421984 4.408979
#> [15,] 3.969437 3.757825
#> [16,] 4.135121 3.838550
#> CAACCTCCACGAGGTA-300.1.2 CAAGAAACATTCTCAT-300.1.2
#> [1,] 4.671996 4.325030
#> [2,] 3.658915 3.770463
#> [3,] 3.909884 4.540925
#> [4,] 4.389535 4.143535
#> [5,] 4.900678 4.544484
#> [6,] 3.893411 4.243179
#> [7,] 4.864826 4.642349
#> [8,] 4.187500 4.390866
#> [9,] 3.977713 4.289442
#> [10,] 3.903585 4.021352
#> [11,] 3.870155 4.381969
#> [12,] 3.812500 4.178529
#> [13,] 4.171027 4.275801
#> [14,] 4.249516 4.048043
#> [15,] 3.823643 4.040332
#> [16,] 4.011628 4.335706
#> CAAGATCCACGCCAGT-300.1.2 CAAGTTGGTCACCCAG-300.1.2
#> [1,] 4.426573 4.445808
#> [2,] 3.963390 4.328221
#> [3,] 4.221308 4.348671
#> [4,] 4.315097 4.599182
#> [5,] 4.949815 4.412065
#> [6,] 3.824352 4.238241
#> [7,] 4.591115 4.510225
#> [8,] 4.548745 4.645194
#> [9,] 4.297408 4.622699
#> [10,] 3.953517 4.469325
#> [11,] 4.154258 4.117587
#> [12,] 4.154669 4.440695
#> [13,] 4.447552 4.560327
#> [14,] 3.946113 3.997955
#> [15,] 4.113945 3.871166
#> [16,] 4.243521 4.313906
#> CACAAACTCATCACCC-300.1.2 CACACCTTCTTAGCCC-300.1.2
#> [1,] 4.593043 4.210814
#> [2,] 4.150435 4.481774
#> [3,] 4.233913 4.362697
#> [4,] 4.111304 4.340826
#> [5,] 4.386087 4.606318
#> [6,] 4.065217 3.907655
#> [7,] 4.455652 4.760024
#> [8,] 4.628696 4.861482
#> [9,] 4.625217 4.433171
#> [10,] 4.142609 4.471446
#> [11,] 4.025217 4.458080
#> [12,] 4.741739 4.362090
#> [13,] 5.076522 4.133657
#> [14,] 3.990435 4.290401
#> [15,] 4.249565 4.195018
#> [16,] 4.462609 4.565006
#> CACAGTAAGATCCTGT-300.1.2 CACAGTAGTAGCGATG-300.1.2
#> [1,] 4.579295 4.407821
#> [2,] 4.011013 4.187550
#> [3,] 4.133921 4.090184
#> [4,] 4.078414 4.256185
#> [5,] 4.868722 4.348763
#> [6,] 4.046256 4.267358
#> [7,] 4.647137 4.652035
#> [8,] 4.434802 4.610535
#> [9,] 4.241850 4.430966
#> [10,] 3.924670 4.307263
#> [11,] 4.320264 3.964086
#> [12,] 3.946256 4.403831
#> [13,] 4.278414 4.774940
#> [14,] 4.138767 4.030327
#> [15,] 4.002643 4.215483
#> [16,] 4.659912 4.504389
#> CACAGTAGTCAGAAGC-300.1.2 CACAGTAGTTCTCATT-300.1.2
#> [1,] 4.660397 4.257193
#> [2,] 3.839858 4.199648
#> [3,] 4.167768 4.507927
#> [4,] 4.208948 4.294187
#> [5,] 5.175902 4.556078
#> [6,] 3.896797 4.013506
#> [7,] 5.345196 4.219025
#> [8,] 4.081851 4.582501
#> [9,] 3.924759 4.234292
#> [10,] 3.776309 4.212566
#> [11,] 3.924250 3.994128
#> [12,] 3.962888 4.453318
#> [13,] 4.168785 4.284792
#> [14,] 4.389426 4.140341
#> [15,] 3.633452 4.469759
#> [16,] 3.868327 4.277745
#> CACATAGCACAACGTT-300.1.2 CACATTTTCAGTTAGC-300.1.2
#> [1,] 4.422351 4.428571
#> [2,] 3.981132 4.190644
#> [3,] 4.030963 3.907948
#> [4,] 4.177068 4.056841
#> [5,] 5.087083 4.987928
#> [6,] 3.933237 4.068913
#> [7,] 4.720851 4.453722
#> [8,] 4.389937 4.233400
#> [9,] 3.833091 4.219316
#> [10,] 4.015481 3.824950
#> [11,] 3.914369 4.042757
#> [12,] 3.881955 4.033702
#> [13,] 4.222545 4.401408
#> [14,] 4.116110 4.198692
#> [15,] 4.083696 4.160966
#> [16,] 4.243348 4.667505
#> CACATTTTCATGTCCC-300.1.2 CACCACTCAGAGCCAA-300.1.2
#> [1,] 4.262105 4.660744
#> [2,] 3.812632 3.699611
#> [3,] 3.946842 4.188784
#> [4,] 4.084737 4.373681
#> [5,] 4.897895 4.992227
#> [6,] 3.808947 3.790117
#> [7,] 4.978947 4.762909
#> [8,] 4.150526 4.277068
#> [9,] 4.117368 4.261521
#> [10,] 3.778421 3.936147
#> [11,] 3.737895 3.970017
#> [12,] 3.893684 4.210994
#> [13,] 4.489474 4.095502
#> [14,] 3.912105 4.236535
#> [15,] 3.860526 4.013326
#> [16,] 4.362632 3.975569
#> CACCAGGTCATCTGCC-300.1.2 CAGAGAGCACTTCTGC-300.1.2
#> [1,] 4.852927 5.084154
#> [2,] 3.679245 3.939570
#> [3,] 4.020803 3.983885
#> [4,] 4.327044 4.358102
#> [5,] 5.186260 5.296777
#> [6,] 3.883406 3.892122
#> [7,] 4.862119 4.550582
#> [8,] 4.584422 4.442256
#> [9,] 4.210450 3.939123
#> [10,] 3.586357 3.755148
#> [11,] 4.116110 3.959714
#> [12,] 3.959845 3.952551
#> [13,] 4.156749 4.132498
#> [14,] 4.283019 3.909579
#> [15,] 4.155298 4.059982
#> [16,] 4.389453 4.713966
#> CAGCATAAGTGGGTTG-300.1.2 CAGCATAGTGCAGTAG-300.1.2
#> [1,] 4.629357 4.490735
#> [2,] 3.792833 4.332268
#> [3,] 4.292096 4.010863
#> [4,] 4.251350 4.067093
#> [5,] 4.920471 4.824281
#> [6,] 3.937653 4.090096
#> [7,] 4.261168 4.223642
#> [8,] 4.663230 4.796805
#> [9,] 4.283260 4.824281
#> [10,] 3.673540 4.126518
#> [11,] 4.144821 4.235144
#> [12,] 4.054001 4.505431
#> [13,] 4.295533 4.795527
#> [14,] 4.127148 4.191054
#> [15,] 4.170349 3.997444
#> [16,] 4.538537 4.182109
#> CAGCGACCATCACCCT-300.1.2 CAGCTAAAGGAATGGA-300.1.2
#> [1,] 4.616712 4.388937
#> [2,] 4.148955 3.708624
#> [3,] 4.176203 4.100610
#> [4,] 4.177112 4.422909
#> [5,] 4.562216 4.910279
#> [6,] 4.183470 3.825348
#> [7,] 4.128974 5.145470
#> [8,] 4.708447 4.379355
#> [9,] 4.426885 4.243467
#> [10,] 4.155313 3.959930
#> [11,] 4.081744 4.367596
#> [12,] 4.241599 3.949913
#> [13,] 4.220708 4.314895
#> [14,] 4.240690 4.233449
#> [15,] 3.825613 3.828397
#> [16,] 4.315168 4.100174
#> CAGCTAACAATAGAGT-300.1.2 CAGTAACGTCGCTTCT-300.1.2
#> [1,] 4.264069 4.421212
#> [2,] 4.002706 4.490909
#> [3,] 4.057900 4.159848
#> [4,] 4.454545 3.809848
#> [5,] 4.729978 4.632576
#> [6,] 4.035173 3.738636
#> [7,] 5.147186 3.751515
#> [8,] 4.212662 5.084091
#> [9,] 4.275433 4.213636
#> [10,] 4.235390 4.010606
#> [11,] 4.107684 4.096970
#> [12,] 3.981602 3.965909
#> [13,] 4.575758 4.818939
#> [14,] 4.290584 4.367424
#> [15,] 3.693723 3.797727
#> [16,] 4.228896 4.456818
#> CAGTCCTCATACGCCG-300.1.2 CATATGGCACAGCCCA-300.1.2
#> [1,] 4.660330 4.533742
#> [2,] 3.723862 3.817485
#> [3,] 3.770885 3.832311
#> [4,] 3.973487 4.143149
#> [5,] 5.168584 5.303170
#> [6,] 3.772386 4.297546
#> [7,] 4.635318 4.932515
#> [8,] 3.994997 4.131902
#> [9,] 4.041021 3.818507
#> [10,] 3.962481 3.947853
#> [11,] 4.067034 4.397239
#> [12,] 4.117059 3.739775
#> [13,] 4.316158 4.238753
#> [14,] 4.645823 4.144683
#> [15,] 3.847424 4.042434
#> [16,] 4.122061 3.934049
#> CATATGGCAGGCTCAC-300.1.2 CATCAAGGTCGCTTCT-300.1.2
#> [1,] 4.733425 4.960773
#> [2,] 3.783610 3.688525
#> [3,] 4.144107 4.310304
#> [4,] 4.240792 4.378220
#> [5,] 4.961326 4.927986
#> [6,] 3.894567 3.824941
#> [7,] 5.002762 4.711358
#> [8,] 4.360958 4.148126
#> [9,] 3.911142 4.327869
#> [10,] 4.051105 3.901639
#> [11,] 4.480663 4.194379
#> [12,] 3.931400 4.197892
#> [13,] 3.928177 4.226581
#> [14,] 4.265193 3.960187
#> [15,] 3.913444 4.317330
#> [16,] 4.180939 4.611241
#> CATCGGGTCACTCTTA-300.1.2 CATGACATCATCGGAT-300.1.2
#> [1,] 5.198519 4.494321
#> [2,] 3.283457 4.089877
#> [3,] 3.803457 4.126420
#> [4,] 4.213827 3.928395
#> [5,] 5.337284 4.909630
#> [6,] 3.755062 4.021728
#> [7,] 4.900741 4.498272
#> [8,] 4.200000 4.228148
#> [9,] 3.986173 4.248889
#> [10,] 3.577284 3.943704
#> [11,] 4.081481 4.306667
#> [12,] 4.112099 4.037037
#> [13,] 4.011358 4.164938
#> [14,] 4.307160 4.260741
#> [15,] 4.020247 3.970864
#> [16,] 4.216296 4.542716
#> CATGCCTGTTGTCTTT-300.1.2 CATGGCGCAAAGAATC-300.1.2
#> [1,] 4.673876 4.322335
#> [2,] 3.993215 3.714890
#> [3,] 3.973707 3.934433
#> [4,] 4.186175 4.404822
#> [5,] 4.573791 4.866328
#> [6,] 3.947837 4.103215
#> [7,] 4.123410 5.037225
#> [8,] 4.687871 4.299492
#> [9,] 4.449958 4.184856
#> [10,] 3.972858 3.980541
#> [11,] 3.901612 4.274535
#> [12,] 4.285835 3.917090
#> [13,] 4.511874 4.319797
#> [14,] 4.107718 4.182741
#> [15,] 4.014419 3.641709
#> [16,] 4.279474 4.186971
#> CATTCGCGTGATAAAC-300.1.2 CCAATCCTCATCGGAT-300.1.2
#> [1,] 4.500000 4.162609
#> [2,] 3.741379 4.465217
#> [3,] 3.908215 4.516522
#> [4,] 4.413286 4.279130
#> [5,] 4.723124 4.333913
#> [6,] 4.053245 4.151304
#> [7,] 5.021298 4.397391
#> [8,] 4.318458 5.060000
#> [9,] 4.032454 4.837391
#> [10,] 3.997972 4.459130
#> [11,] 4.086714 4.527826
#> [12,] 3.902130 4.610435
#> [13,] 4.287525 4.571304
#> [14,] 4.131846 4.286957
#> [15,] 3.688134 4.328696
#> [16,] 4.032454 4.813043
#> CCACCTAAGCTTTGGT-300.1.2 CCACGGAAGACCGGAT-300.1.2
#> [1,] 4.726975 4.596231
#> [2,] 3.895278 3.887493
#> [3,] 3.873305 4.190748
#> [4,] 4.187003 3.711593
#> [5,] 5.068724 4.744146
#> [6,] 4.285647 4.006853
#> [7,] 4.463768 4.660765
#> [8,] 4.557737 4.207310
#> [9,] 4.135110 4.332381
#> [10,] 4.088359 4.123358
#> [11,] 3.955119 4.414620
#> [12,] 4.274427 4.536265
#> [13,] 4.403927 4.396916
#> [14,] 4.050491 4.319817
#> [15,] 4.142590 3.922901
#> [16,] 4.243104 3.957738
#> CCATGTCGTACAGTTC-300.1.2 CCCAATCGTAGCGCTC-300.1.2
#> [1,] 4.284702 4.910756
#> [2,] 4.079507 3.532452
#> [3,] 4.369457 3.988178
#> [4,] 4.202309 4.315253
#> [5,] 4.747310 5.146268
#> [6,] 3.979795 3.819425
#> [7,] 4.626345 4.800649
#> [8,] 4.405930 4.190774
#> [9,] 4.303857 4.199815
#> [10,] 4.125951 3.805981
#> [11,] 4.098137 4.089476
#> [12,] 4.356862 4.040102
#> [13,] 4.229861 4.262401
#> [14,] 4.152453 4.187529
#> [15,] 4.206770 3.890125
#> [16,] 4.276305 4.121465
#> CCCAATCTCCACGTTC-300.1.2 CCCAGTTAGGCCCTTG-300.1.2
#> [1,] 4.425801 4.236628
#> [2,] 4.023609 3.811297
#> [3,] 4.143339 3.916132
#> [4,] 4.120573 4.123663
#> [5,] 4.823777 4.939238
#> [6,] 4.285835 4.104835
#> [7,] 4.018550 5.008986
#> [8,] 4.498314 3.975610
#> [9,] 4.191400 4.279846
#> [10,] 4.118887 3.967908
#> [11,] 3.993255 3.989303
#> [12,] 4.050590 3.920411
#> [13,] 4.566610 4.385965
#> [14,] 4.084317 4.299101
#> [15,] 3.844857 3.747540
#> [16,] 4.618044 4.120240
#> CCCTCCTTCGCCAGCA-300.1.2 CCGGGATGTCACACGC-300.1.2
#> [1,] 4.819703 4.392710
#> [2,] 3.945481 4.077521
#> [3,] 4.103778 4.358931
#> [4,] 4.276423 4.200972
#> [5,] 5.264467 5.020413
#> [6,] 4.042085 4.116403
#> [7,] 5.114778 4.672418
#> [8,] 4.090866 4.371324
#> [9,] 4.151602 4.286513
#> [10,] 3.844572 4.085055
#> [11,] 3.942133 4.280680
#> [12,] 3.943089 4.261968
#> [13,] 4.387374 4.324909
#> [14,] 4.218556 4.162090
#> [15,] 3.611191 4.254678
#> [16,] 3.702535 4.285541
#> CCGTGGAAGGGCTCTC-300.1.2 CCGTTCACACATGGGA-300.1.2
#> [1,] 4.511759 4.724308
#> [2,] 3.652869 4.005538
#> [3,] 3.975071 3.964308
#> [4,] 4.297272 4.091692
#> [5,] 5.318909 4.748923
#> [6,] 3.823142 3.880615
#> [7,] 5.035748 4.389538
#> [8,] 4.209313 4.593231
#> [9,] 3.999530 4.223385
#> [10,] 3.659454 3.908923
#> [11,] 4.069614 4.171077
#> [12,] 3.841957 4.107077
#> [13,] 4.088899 4.504615
#> [14,] 4.255880 3.922462
#> [15,] 4.061618 3.852923
#> [16,] 4.316557 4.630769
#> CCGTTCATCCAGAGGA-300.1.2 CCTAAAGTCGGAATCT-300.1.2
#> [1,] 4.606292 4.588889
#> [2,] 3.937083 4.052910
#> [3,] 4.246902 4.125397
#> [4,] 4.401335 4.085714
#> [5,] 4.680648 4.629101
#> [6,] 3.881792 4.102646
#> [7,] 4.261201 3.951852
#> [8,] 4.464252 4.650794
#> [9,] 4.515729 4.267725
#> [10,] 4.211630 3.999471
#> [11,] 4.180172 4.073545
#> [12,] 4.308866 4.253439
#> [13,] 4.270734 4.441270
#> [14,] 4.298379 3.946561
#> [15,] 4.337464 4.231746
#> [16,] 4.254528 4.188889
#> CCTAGCTAGTCCGTAT-300.1.2 CCTATTACATTGTGCA-300.1.2
#> [1,] 4.477357 4.249237
#> [2,] 4.261588 4.280773
#> [3,] 4.190730 4.214649
#> [4,] 4.103356 4.171923
#> [5,] 4.594566 4.396745
#> [6,] 4.091103 4.279756
#> [7,] 4.428876 4.068159
#> [8,] 4.427278 4.712106
#> [9,] 4.229089 4.259410
#> [10,] 3.998402 4.526958
#> [11,] 4.163559 4.046796
#> [12,] 4.166223 4.074262
#> [13,] 4.375599 4.545270
#> [14,] 4.256793 4.095626
#> [15,] 3.997869 4.104781
#> [16,] 4.359616 4.378433
#> CCTTCCCTCCTAGAAC-300.1.2 CCTTTCTTCGCCATAA-300.1.2
#> [1,] 4.344221 4.572150
#> [2,] 4.261307 4.166667
#> [3,] 4.398660 4.251804
#> [4,] 4.033501 4.282828
#> [5,] 4.520938 4.556999
#> [6,] 3.899497 4.355700
#> [7,] 4.578727 4.666667
#> [8,] 4.672529 4.314574
#> [9,] 4.286432 4.036075
#> [10,] 4.184255 4.140693
#> [11,] 4.339196 4.098846
#> [12,] 4.251256 4.191919
#> [13,] 4.520938 4.248196
#> [14,] 3.981575 4.253247
#> [15,] 4.336683 4.394661
#> [16,] 4.379397 4.447330
#> CGAACATAGAGTTGGC-300.1.2 CGAACATAGTAGGTGC-300.1.2
#> [1,] 4.469816 4.457889
#> [2,] 3.656693 4.211620
#> [3,] 3.872441 4.348614
#> [4,] 4.111811 4.187633
#> [5,] 5.313386 4.672175
#> [6,] 3.772703 4.141791
#> [7,] 5.035171 4.407783
#> [8,] 4.176378 4.446162
#> [9,] 3.917060 4.356610
#> [10,] 3.975328 4.129531
#> [11,] 3.899213 4.060768
#> [12,] 3.806299 4.120469
#> [13,] 4.165354 4.424307
#> [14,] 4.129134 4.155117
#> [15,] 3.982152 3.897122
#> [16,] 4.196850 4.526652
#> CGAACATCAGTCGATT-300.1.2 CGACCTTAGGAATGGA-300.1.2
#> [1,] 4.941693 4.842899
#> [2,] 4.532748 3.537391
#> [3,] 4.071086 3.897391
#> [4,] 4.110224 4.206377
#> [5,] 4.369010 4.595942
#> [6,] 4.611821 4.283478
#> [7,] 4.343450 4.542609
#> [8,] 4.912141 4.264348
#> [9,] 4.392173 4.046377
#> [10,] 4.607827 3.912464
#> [11,] 4.331470 4.496232
#> [12,] 4.198083 4.140290
#> [13,] 4.754792 4.129855
#> [14,] 4.288339 4.055652
#> [15,] 4.007188 3.857391
#> [16,] 4.255591 4.152464
#> CGACTTCAGTGCCAGA-300.1.2 CGATGGCTCCTCATTA-300.1.2
#> [1,] 4.559771 4.585300
#> [2,] 3.540803 3.761803
#> [3,] 4.068813 4.097103
#> [4,] 4.006176 4.108906
#> [5,] 4.745920 5.142167
#> [6,] 4.187031 3.792382
#> [7,] 4.710190 4.786481
#> [8,] 4.361712 4.129292
#> [9,] 4.095280 4.644313
#> [10,] 3.889722 3.758047
#> [11,] 4.528893 3.960837
#> [12,] 4.363917 4.107296
#> [13,] 4.348919 4.345494
#> [14,] 4.047640 4.516631
#> [15,] 3.805470 3.641631
#> [16,] 4.035730 3.855687
#> CGATTGAGTAACGACG-300.1.2 CGCTTCAAGGCATGGT-300.1.2
#> [1,] 4.592628 4.950622
#> [2,] 3.818526 3.912131
#> [3,] 4.103970 3.981337
#> [4,] 4.117202 4.156687
#> [5,] 4.579395 5.516330
#> [6,] 4.190926 3.872084
#> [7,] 4.605860 4.704510
#> [8,] 4.328922 4.193235
#> [9,] 4.007561 4.004666
#> [10,] 4.187146 3.641135
#> [11,] 4.164461 4.314930
#> [12,] 4.424386 3.823872
#> [13,] 4.043478 3.998834
#> [14,] 4.226843 4.382582
#> [15,] 4.139887 4.190513
#> [16,] 4.122873 4.708398
#> CGGACACCATTGGTAC-300.1.2 CGGAGCTTCAATAAGG-300.1.2
#> [1,] 4.392364 4.424364
#> [2,] 4.279448 3.863008
#> [3,] 4.239643 4.046854
#> [4,] 4.516653 4.445783
#> [5,] 4.527214 4.695672
#> [6,] 4.554021 4.166444
#> [7,] 4.411860 5.132976
#> [8,] 5.069050 4.236055
#> [9,] 5.032494 4.024096
#> [10,] 4.398050 3.942436
#> [11,] 4.288383 4.053101
#> [12,] 4.337937 3.954485
#> [13,] 4.326564 4.406515
#> [14,] 4.153534 4.172245
#> [15,] 4.005686 3.879518
#> [16,] 4.711617 4.268630
#> CGGAGTCAGAGAACAG-300.1.2 CGGAGTCCAAATTGCC-300.1.2
#> [1,] 4.563021 4.299911
#> [2,] 3.977841 4.018717
#> [3,] 4.215630 4.051916
#> [4,] 4.166071 4.272504
#> [5,] 4.676436 4.945187
#> [6,] 3.911127 4.056373
#> [7,] 4.431499 4.905971
#> [8,] 4.385275 4.488191
#> [9,] 4.205623 4.108512
#> [10,] 4.057660 4.084002
#> [11,] 4.008816 4.191622
#> [12,] 4.460805 3.951203
#> [13,] 4.380986 4.192291
#> [14,] 3.973314 4.424911
#> [15,] 4.668335 3.951872
#> [16,] 4.250179 4.096702
#> CGGAGTCCAACACGCC-300.1.2 CGGCTAGGTCCGCTGA-300.1.2
#> [1,] 4.344059 4.480231
#> [2,] 3.914191 4.019286
#> [3,] 4.490099 4.105111
#> [4,] 3.877063 4.200579
#> [5,] 4.685644 4.505304
#> [6,] 4.150990 4.234330
#> [7,] 4.792079 4.195757
#> [8,] 4.411716 4.578592
#> [9,] 3.910066 4.239151
#> [10,] 4.344884 4.314368
#> [11,] 4.335809 4.051109
#> [12,] 4.231023 4.561234
#> [13,] 4.159241 4.767599
#> [14,] 4.265677 4.128255
#> [15,] 4.466172 4.107040
#> [16,] 4.447195 4.361620
#> CGGTTAAAGATCTGCT-300.1.2 CGGTTAACAAGTAGTA-300.1.2
#> [1,] 4.488265 4.880605
#> [2,] 3.653571 3.228884
#> [3,] 3.870408 3.522419
#> [4,] 4.363265 4.423879
#> [5,] 4.938776 5.202815
#> [6,] 3.931633 3.759645
#> [7,] 4.869388 4.739312
#> [8,] 4.426020 4.235662
#> [9,] 4.172449 4.430136
#> [10,] 3.944898 3.761731
#> [11,] 4.174490 3.646507
#> [12,] 3.841327 4.125130
#> [13,] 4.450000 4.289364
#> [14,] 4.096939 4.338895
#> [15,] 3.682143 3.702294
#> [16,] 4.029082 3.683525
#> CGTAGCGAGGCTATCT-300.1.2 CGTAGGCAGCGCCTTG-300.1.2
#> [1,] 4.849233 4.687831
#> [2,] 4.038692 3.983720
#> [3,] 4.164109 4.181522
#> [4,] 4.146097 4.252340
#> [5,] 4.807872 4.597477
#> [6,] 4.034690 4.228327
#> [7,] 4.065377 4.489621
#> [8,] 4.448299 4.673179
#> [9,] 4.095397 4.507530
#> [10,] 4.027352 4.112332
#> [11,] 4.109406 4.316239
#> [12,] 4.086057 4.399267
#> [13,] 4.179453 4.129426
#> [14,] 4.058706 4.068376
#> [15,] 4.206137 4.002035
#> [16,] 4.552368 4.715507
#> CGTAGGCGTTCCCTTG-300.1.2 CGTCACTAGGCTCATT-300.1.2
#> [1,] 4.414432 4.223047
#> [2,] 3.532567 4.578350
#> [3,] 3.759898 4.374509
#> [4,] 4.321839 3.951550
#> [5,] 4.860792 4.427324
#> [6,] 3.905492 3.984286
#> [7,] 5.077267 3.977739
#> [8,] 4.047893 4.754256
#> [9,] 3.948276 4.118725
#> [10,] 3.791826 4.167612
#> [11,] 3.568327 4.593191
#> [12,] 3.722861 4.170231
#> [13,] 4.294381 4.223483
#> [14,] 4.310345 4.580969
#> [15,] 3.759259 3.981667
#> [16,] 4.087484 4.390223
#> CGTCACTAGTACATGA-300.1.2 CGTCACTAGTAGTGCG-300.1.2
#> [1,] 4.457965 4.356564
#> [2,] 3.894690 3.952188
#> [3,] 4.134513 4.015802
#> [4,] 4.390708 4.045786
#> [5,] 5.159735 5.179903
#> [6,] 4.042035 4.038088
#> [7,] 5.182301 4.860616
#> [8,] 4.312832 4.220827
#> [9,] 4.452655 4.136548
#> [10,] 3.910619 3.883306
#> [11,] 4.176549 3.946921
#> [12,] 3.791593 4.079011
#> [13,] 4.169912 4.195705
#> [14,] 4.457522 4.240681
#> [15,] 3.731858 3.898703
#> [16,] 3.911504 4.322123
#> CGTCAGGAGATCGGGT-300.1.2 CGTCAGGCACCGATAT-300.1.2
#> [1,] 4.294324 4.820626
#> [2,] 4.167349 3.690127
#> [3,] 4.210064 3.906158
#> [4,] 4.188999 4.086999
#> [5,] 4.534816 5.265396
#> [6,] 4.332358 3.818671
#> [7,] 4.543593 4.849951
#> [8,] 4.795202 4.158358
#> [9,] 4.503218 3.999511
#> [10,] 4.303101 3.638319
#> [11,] 4.318900 4.016618
#> [12,] 4.543593 3.972141
#> [13,] 4.008777 4.318182
#> [14,] 4.071387 4.332356
#> [15,] 4.322411 4.105572
#> [16,] 4.364541 4.606549
#> CGTCAGGGTTACAGAA-300.1.2 CGTGTAAAGAGTACCG-300.1.2
#> [1,] 4.347258 4.625781
#> [2,] 3.985379 4.017187
#> [3,] 4.172324 4.373438
#> [4,] 4.173368 4.053906
#> [5,] 4.907050 4.600781
#> [6,] 3.973890 4.200781
#> [7,] 4.506005 4.750000
#> [8,] 4.547258 4.081250
#> [9,] 4.427154 4.323438
#> [10,] 4.036031 4.132813
#> [11,] 4.254830 4.096875
#> [12,] 4.229243 4.214844
#> [13,] 4.338903 4.187500
#> [14,] 4.293995 4.408594
#> [15,] 4.093473 4.145313
#> [16,] 4.275718 4.260938
#> CGTTAGATCGGCGCAT-300.1.2 CGTTGGGAGAGTGAGA-300.1.2
#> [1,] 4.478448 4.508397
#> [2,] 3.884339 3.517557
#> [3,] 4.030891 3.890076
#> [4,] 3.793103 4.336641
#> [5,] 4.650144 5.035878
#> [6,] 3.968391 4.103817
#> [7,] 4.135057 4.906870
#> [8,] 4.525144 4.177863
#> [9,] 4.236351 3.743511
#> [10,] 3.933190 3.607634
#> [11,] 3.934626 4.160305
#> [12,] 4.127874 3.736641
#> [13,] 4.544540 4.077863
#> [14,] 4.284483 4.164885
#> [15,] 4.130029 3.862595
#> [16,] 4.778736 3.763359
#> CGTTGGGTCACCCGAG-300.1.2 CTAATGGAGAACAACT-300.1.2
#> [1,] 4.401195 4.237066
#> [2,] 4.106521 4.173543
#> [3,] 4.218517 4.284872
#> [4,] 4.075660 4.360838
#> [5,] 4.924340 4.686968
#> [6,] 4.007466 4.026195
#> [7,] 4.516675 4.706614
#> [8,] 4.387755 4.335298
#> [9,] 4.187656 4.311067
#> [10,] 3.934793 4.284217
#> [11,] 3.967646 4.228553
#> [12,] 3.893977 4.373936
#> [13,] 4.484321 4.147348
#> [14,] 4.208064 4.353635
#> [15,] 4.024888 4.026195
#> [16,] 4.659034 4.193844
#> CTACATTGTTGGAGGT-300.1.2 CTACGTCAGACTAGGC-300.1.2
#> [1,] 4.763748 4.939646
#> [2,] 3.790173 3.425249
#> [3,] 4.024996 3.810631
#> [4,] 4.346522 4.045958
#> [5,] 5.102557 5.269657
#> [6,] 3.787602 3.873754
#> [7,] 4.973575 5.068660
#> [8,] 4.285102 4.224252
#> [9,] 4.031281 4.060354
#> [10,] 3.818883 3.547065
#> [11,] 4.106556 4.129014
#> [12,] 3.925725 4.053156
#> [13,] 4.303242 4.252492
#> [14,] 4.305385 4.200997
#> [15,] 3.913584 4.357697
#> [16,] 4.051850 4.611849
#> CTAGCCTGTACATCCA-300.1.2 CTAGCCTGTTCGAATC-300.1.2
#> [1,] 4.438805 4.548520
#> [2,] 3.700190 3.717516
#> [3,] 3.909867 3.917763
#> [4,] 3.926945 4.453536
#> [5,] 5.556452 4.669819
#> [6,] 4.020398 4.008635
#> [7,] 5.283681 5.024671
#> [8,] 4.084915 4.367187
#> [9,] 3.929791 3.957237
#> [10,] 3.776091 3.937911
#> [11,] 3.909867 3.916118
#> [12,] 3.836338 3.863898
#> [13,] 4.346300 4.099918
#> [14,] 4.398482 4.143092
#> [15,] 3.936907 3.759868
#> [16,] 4.290323 4.048520
#> CTAGTGAAGGCATTGG-300.1.2 CTAGTGACATAACCTG-300.1.2
#> [1,] 4.529136 4.638355
#> [2,] 3.874089 3.850522
#> [3,] 4.084807 4.133637
#> [4,] 4.263788 4.256657
#> [5,] 4.905827 5.248905
#> [6,] 4.202914 3.980957
#> [7,] 4.921956 4.765925
#> [8,] 4.444849 4.156387
#> [9,] 4.222164 3.953657
#> [10,] 4.007804 3.861476
#> [11,] 4.189386 4.052578
#> [12,] 3.945369 4.067914
#> [13,] 4.181582 4.221773
#> [14,] 4.398023 4.243680
#> [15,] 4.077523 4.039771
#> [16,] 4.030697 4.425177
#> CTCCTAGCAATAAGCA-300.1.2 CTCGAAACAGCATACT-300.1.2
#> [1,] 4.567452 4.610901
#> [2,] 3.930764 3.757002
#> [3,] 3.957887 3.931870
#> [4,] 3.926481 4.262680
#> [5,] 5.189151 5.322483
#> [6,] 3.663812 3.841787
#> [7,] 4.816560 4.822861
#> [8,] 4.466809 4.024981
#> [9,] 4.407566 3.719909
#> [10,] 3.573162 3.887207
#> [11,] 4.596003 4.321726
#> [12,] 3.965025 3.695685
#> [13,] 3.758030 4.239970
#> [14,] 4.801570 4.290689
#> [15,] 3.579586 4.037850
#> [16,] 4.336188 4.185466
#> CTCGAGGTCGTTGCCT-300.1.2 CTCGGGACAATAGCAA-300.1.2
#> [1,] 4.912811 4.566867
#> [2,] 3.824733 3.840814
#> [3,] 4.052491 3.941231
#> [4,] 4.000000 4.416474
#> [5,] 5.524911 4.950486
#> [6,] 3.772242 4.121240
#> [7,] 4.461744 5.124479
#> [8,] 4.106762 4.227672
#> [9,] 4.098754 4.398889
#> [10,] 3.887011 4.049514
#> [11,] 4.746441 3.956039
#> [12,] 4.135231 4.078667
#> [13,] 4.292705 4.217029
#> [14,] 4.219751 4.356317
#> [15,] 4.374555 3.880148
#> [16,] 4.788256 4.113836
#> CTCGTCAAGTTACCCA-300.1.2 CTCTAATAGAGGTACC-300.1.2
#> [1,] 4.594859 4.604898
#> [2,] 3.799266 3.711429
#> [3,] 4.067319 3.896327
#> [4,] 3.977356 4.296735
#> [5,] 5.074663 5.203265
#> [6,] 4.250306 3.799592
#> [7,] 4.648715 4.822041
#> [8,] 4.383109 4.157551
#> [9,] 4.207466 4.072245
#> [10,] 4.161567 3.725714
#> [11,] 4.273562 3.755918
#> [12,] 4.268666 4.017551
#> [13,] 4.400245 4.323265
#> [14,] 4.187271 4.195510
#> [15,] 3.951652 3.893469
#> [16,] 4.255814 4.313061
#> CTCTAATCATGGTCTA-300.1.2 CTCTACGAGTCACGCC-300.1.2
#> [1,] 4.411206 4.334980
#> [2,] 4.573287 4.237154
#> [3,] 4.264132 4.075099
#> [4,] 4.058529 4.446640
#> [5,] 4.393697 4.572134
#> [6,] 3.890945 4.047431
#> [7,] 4.106053 3.959486
#> [8,] 5.067534 4.756917
#> [9,] 4.109055 4.491107
#> [10,] 4.169585 4.307312
#> [11,] 4.473237 4.212451
#> [12,] 4.216108 4.190711
#> [13,] 4.301651 4.648221
#> [14,] 4.353677 4.314229
#> [15,] 3.849425 4.025692
#> [16,] 4.227114 4.276680
#> CTGAAGTGTACAGTTC-300.1.2 CTGATCCCACATTCGA-300.1.2
#> [1,] 4.473868 4.606303
#> [2,] 3.805575 3.817498
#> [3,] 4.098955 4.028222
#> [4,] 4.541463 4.453904
#> [5,] 4.739373 4.835372
#> [6,] 4.154007 3.859831
#> [7,] 4.790941 5.047507
#> [8,] 4.328920 4.320320
#> [9,] 4.237631 4.096896
#> [10,] 3.937979 3.949671
#> [11,] 4.200000 4.325964
#> [12,] 3.855052 3.977893
#> [13,] 4.230662 4.258702
#> [14,] 4.263415 4.191439
#> [15,] 3.965157 3.735183
#> [16,] 3.942160 3.994356
#> CTGCCTAGTTGCGTTA-300.1.2 CTGCGGAAGCTATGCT-300.1.2
#> [1,] 4.652607 4.519541
#> [2,] 3.771564 3.860865
#> [3,] 4.084834 4.149557
#> [4,] 4.267773 3.984367
#> [5,] 5.099526 4.820219
#> [6,] 4.014218 4.321001
#> [7,] 4.969194 4.547681
#> [8,] 4.240758 4.339239
#> [9,] 4.062085 4.230328
#> [10,] 3.870142 4.017718
#> [11,] 4.042654 4.433038
#> [12,] 3.963507 4.433559
#> [13,] 4.177251 4.408546
#> [14,] 4.286730 3.956227
#> [15,] 3.788152 3.870245
#> [16,] 3.854976 4.078687
#> CTGCTGTGTAGCCTCG-300.1.2 CTGGTCTAGCGTTGCC-300.1.2
#> [1,] 4.390082 4.275349
#> [2,] 3.783742 3.880930
#> [3,] 4.267382 4.248837
#> [4,] 4.351227 4.126512
#> [5,] 4.928937 4.602791
#> [6,] 3.855317 4.075814
#> [7,] 4.573108 4.726977
#> [8,] 4.264826 4.439535
#> [9,] 4.231084 4.299070
#> [10,] 4.066973 3.956279
#> [11,] 3.917689 4.044651
#> [12,] 4.332822 3.936744
#> [13,] 4.245399 4.301395
#> [14,] 4.180470 4.306047
#> [15,] 4.164110 3.844186
#> [16,] 4.163088 4.380000
#> CTGTGCTCACGACGAA-300.1.2 CTGTTTACAGCTGTGC-300.1.2
#> [1,] 4.420187 4.073443
#> [2,] 3.686231 4.368390
#> [3,] 3.775096 3.729142
#> [4,] 3.948985 3.948296
#> [5,] 5.202414 5.471798
#> [6,] 3.974767 3.890717
#> [7,] 4.991772 4.992362
#> [8,] 4.336807 4.617509
#> [9,] 4.365880 3.832550
#> [10,] 4.047175 3.950059
#> [11,] 4.215030 4.429495
#> [12,] 4.085573 3.635135
#> [13,] 4.097093 3.816099
#> [14,] 4.373012 4.884254
#> [15,] 4.256171 3.531727
#> [16,] 4.269336 4.044066
#> CTGTTTACATTGCGGC-300.1.2 GAAATGATCTCGAGTA-300.1.2
#> [1,] 4.251701 4.145797
#> [2,] 4.333333 3.855967
#> [3,] 4.495627 3.901235
#> [4,] 4.137026 4.255144
#> [5,] 4.526725 5.456202
#> [6,] 3.886297 4.018812
#> [7,] 4.298348 5.169312
#> [8,] 4.595724 4.164021
#> [9,] 4.049563 3.892416
#> [10,] 4.180758 4.013521
#> [11,] 4.217687 4.157554
#> [12,] 4.191448 4.075838
#> [13,] 4.275996 4.228101
#> [14,] 4.079689 4.188713
#> [15,] 4.438290 3.776602
#> [16,] 4.318756 4.047031
#> GAACATCCAGTACACT-300.1.2 GAATGAAAGATATACG-300.1.2
#> [1,] 4.369139 4.390558
#> [2,] 3.791134 3.920064
#> [3,] 3.924979 4.283798
#> [4,] 4.037511 4.335300
#> [5,] 4.814152 5.054185
#> [6,] 3.894288 4.170601
#> [7,] 4.872975 4.768240
#> [8,] 4.298380 4.228541
#> [9,] 4.227621 4.038090
#> [10,] 3.983802 4.315987
#> [11,] 4.230179 4.350322
#> [12,] 3.970162 3.975322
#> [13,] 4.196931 4.151824
#> [14,] 4.439898 4.498927
#> [15,] 3.905371 3.931330
#> [16,] 4.165388 4.111052
#> GAATGAAGTCATACTG-300.1.2 GACACGCAGGGAAACA-300.1.2
#> [1,] 4.882553 4.497802
#> [2,] 3.562311 4.047386
#> [3,] 3.682024 4.168051
#> [4,] 4.220921 4.394724
#> [5,] 5.523036 4.495848
#> [6,] 3.807402 4.083537
#> [7,] 4.786631 4.383488
#> [8,] 4.241314 4.522716
#> [9,] 3.766994 4.320469
#> [10,] 3.707704 4.055691
#> [11,] 3.945997 3.956522
#> [12,] 3.896526 4.220811
#> [13,] 4.108006 4.275037
#> [14,] 4.194109 4.170982
#> [15,] 4.042674 4.135320
#> [16,] 4.441088 4.184172
#> GACGCGTAGTTGCAGG-300.1.2 GACGGCTGTATATGAG-300.1.2
#> [1,] 4.545818 4.304275
#> [2,] 3.647119 4.251467
#> [3,] 3.913004 3.992456
#> [4,] 4.404820 4.290863
#> [5,] 4.996262 4.689019
#> [6,] 3.832066 4.008382
#> [7,] 4.730378 4.213747
#> [8,] 4.263178 4.963956
#> [9,] 4.108648 4.590947
#> [10,] 3.819822 4.319363
#> [11,] 3.851141 4.050293
#> [12,] 4.034154 4.248114
#> [13,] 4.276582 4.873428
#> [14,] 4.200284 4.274937
#> [15,] 4.089187 4.098072
#> [16,] 4.082743 4.471920
#> GACGGCTGTGCACTTA-300.1.2 GACTAACGTCTTGATG-300.1.2
#> [1,] 4.343677 4.243409
#> [2,] 3.915306 3.731107
#> [3,] 4.178488 3.819859
#> [4,] 4.219552 4.064148
#> [5,] 4.904340 5.382250
#> [6,] 3.915306 4.029877
#> [7,] 4.661923 5.089631
#> [8,] 4.382408 4.176626
#> [9,] 4.042231 3.883128
#> [10,] 3.953103 3.963972
#> [11,] 4.245684 4.024605
#> [12,] 4.034064 4.014938
#> [13,] 4.169155 4.211775
#> [14,] 4.254783 4.676626
#> [15,] 4.073962 3.752197
#> [16,] 4.246617 4.068541
#> GACTGCGCAATGGATA-300.1.2 GAGGTGAAGGGATCTG-300.1.2
#> [1,] 4.417800 4.613152
#> [2,] 3.734240 3.899706
#> [3,] 4.070457 3.926525
#> [4,] 4.139679 4.314842
#> [5,] 4.945612 4.669728
#> [6,] 4.234240 4.197281
#> [7,] 4.676143 4.485305
#> [8,] 4.318912 4.337252
#> [9,] 4.276885 4.497796
#> [10,] 4.144623 4.042983
#> [11,] 4.214462 4.192873
#> [12,] 4.052534 4.313005
#> [13,] 4.405439 4.343497
#> [14,] 4.140297 4.244673
#> [15,] 3.971570 3.939015
#> [16,] 4.282447 4.222630
#> GATCAGTAGCCAGGAT-300.1.2 GATCAGTTCAAGCCTA-300.1.2
#> [1,] 4.300687 4.574257
#> [2,] 4.408935 3.995050
#> [3,] 3.961340 3.864086
#> [4,] 4.066151 3.954995
#> [5,] 4.378007 5.303330
#> [6,] 4.183849 4.174167
#> [7,] 4.445017 4.859136
#> [8,] 4.846220 4.216922
#> [9,] 4.536942 4.139964
#> [10,] 4.233677 3.988299
#> [11,] 4.532646 4.113411
#> [12,] 4.353952 3.919442
#> [13,] 4.302405 4.327183
#> [14,] 4.179553 4.311431
#> [15,] 3.991409 4.024752
#> [16,] 4.535223 4.563006
#> GATCGATTCTTGAGGT-300.1.2 GATCGCGTCAACGGCC-300.1.2
#> [1,] 4.422354 4.454043
#> [2,] 4.191832 4.227524
#> [3,] 4.306287 4.542441
#> [4,] 4.196668 4.454043
#> [5,] 4.640516 4.772476
#> [6,] 4.310586 3.801105
#> [7,] 4.044062 4.084882
#> [8,] 4.379366 4.794073
#> [9,] 4.252015 4.068307
#> [10,] 3.908114 4.005023
#> [11,] 3.981730 4.287293
#> [12,] 4.105857 4.069312
#> [13,] 4.475551 4.374686
#> [14,] 4.223536 4.060271
#> [15,] 4.133262 4.210447
#> [16,] 4.361096 4.352084
#> GATGAGGCACCATCCT-300.1.2 GATGCTAAGAGGTACC-300.1.2
#> [1,] 4.331604 4.354894
#> [2,] 4.020758 3.788271
#> [3,] 4.044110 4.337646
#> [4,] 4.072652 4.031910
#> [5,] 5.035807 4.642518
#> [6,] 4.190970 3.931436
#> [7,] 5.046186 4.622682
#> [8,] 4.292683 4.133247
#> [9,] 4.249092 4.201811
#> [10,] 3.832901 4.033204
#> [11,] 4.122989 3.986632
#> [12,] 3.952776 4.340664
#> [13,] 4.082512 4.226391
#> [14,] 4.459263 4.136697
#> [15,] 3.808511 4.423027
#> [16,] 4.057602 4.319966
#> GATTCAGAGATATACG-300.1.2 GATTCAGAGCGCTCCA-300.1.2
#> [1,] 4.435200 4.706859
#> [2,] 3.958400 3.692879
#> [3,] 4.318933 3.691131
#> [4,] 3.999467 4.000437
#> [5,] 4.756800 5.399301
#> [6,] 3.891200 3.832678
#> [7,] 4.636800 4.717344
#> [8,] 4.218133 4.098733
#> [9,] 4.367467 3.882918
#> [10,] 3.907200 3.626038
#> [11,] 4.331200 3.941022
#> [12,] 4.192000 4.008301
#> [13,] 4.237867 4.112276
#> [14,] 4.384533 4.128440
#> [15,] 4.001600 3.982962
#> [16,] 4.005867 4.381826
#> GATTCAGGTACCCAAT-300.1.2 GCAATCAGTAGCAAAT-300.1.2
#> [1,] 4.449879 4.425157
#> [2,] 3.898551 4.573585
#> [3,] 3.772343 4.364780
#> [4,] 4.448671 4.140881
#> [5,] 4.825483 4.448428
#> [6,] 3.817029 3.985535
#> [7,] 4.536836 4.003145
#> [8,] 4.570048 5.001258
#> [9,] 4.372585 4.617610
#> [10,] 3.721618 3.868553
#> [11,] 4.067029 4.244025
#> [12,] 3.878019 4.135220
#> [13,] 3.940821 4.609434
#> [14,] 4.559783 4.500629
#> [15,] 3.728865 4.055346
#> [16,] 4.003019 4.268553
#> GCAATCAGTCCAGTAT-300.1.2 GCACTCTAGTCTTGCA-300.1.2
#> [1,] 4.893065 4.097266
#> [2,] 3.500671 4.403051
#> [3,] 3.857271 4.339479
#> [4,] 4.116331 4.240941
#> [5,] 5.249217 4.358551
#> [6,] 3.754362 4.026065
#> [7,] 5.131991 4.139860
#> [8,] 4.064877 4.648442
#> [9,] 4.146756 4.396694
#> [10,] 3.693960 4.287985
#> [11,] 4.130201 4.403687
#> [12,] 3.924832 4.267641
#> [13,] 4.127069 4.364908
#> [14,] 4.283669 4.314685
#> [15,] 3.956152 4.109981
#> [16,] 4.104251 4.612206
#> GCAGCCATCAGGCGAA-300.1.2 GCAGTTATCAGGCAAG-300.1.2
#> [1,] 4.747808 4.416055
#> [2,] 3.720990 3.614293
#> [3,] 3.740072 3.934410
#> [4,] 3.953069 4.127753
#> [5,] 5.690562 5.413118
#> [6,] 3.882414 3.863436
#> [7,] 4.885508 4.940284
#> [8,] 3.935018 4.065590
#> [9,] 4.060856 3.923642
#> [10,] 3.744714 3.814488
#> [11,] 3.856111 3.912384
#> [12,] 3.957194 3.999511
#> [13,] 4.375451 4.357807
#> [14,] 4.484270 4.298581
#> [15,] 3.828778 4.010279
#> [16,] 4.441465 4.500734
#> GCATACAAGCCGATTT-300.1.2 GCATGATAGATGAGAG-300.1.2
#> [1,] 4.583068 4.280195
#> [2,] 4.314449 3.901586
#> [3,] 4.384468 3.891419
#> [4,] 4.149586 4.030094
#> [5,] 4.639720 5.304595
#> [6,] 3.935710 3.979260
#> [7,] 4.162954 5.239935
#> [8,] 4.449395 4.413176
#> [9,] 4.345640 4.011387
#> [10,] 4.145767 3.994307
#> [11,] 4.056652 4.004473
#> [12,] 4.259707 4.152501
#> [13,] 4.259071 4.167954
#> [14,] 4.221515 4.329402
#> [15,] 4.099300 3.895893
#> [16,] 4.444303 4.023587
#> GCGACCACACCACCAG-300.1.2 GCGACCATCGTTGCCT-300.1.2
#> [1,] 4.260016 4.343778
#> [2,] 4.300899 4.228290
#> [3,] 4.426002 4.484333
#> [4,] 4.417825 4.284691
#> [5,] 4.430090 4.380483
#> [6,] 4.096484 4.102059
#> [7,] 4.597711 4.395703
#> [8,] 4.417825 4.156670
#> [9,] 4.569910 4.410922
#> [10,] 4.192968 3.929275
#> [11,] 4.314800 4.237243
#> [12,] 4.518397 4.274843
#> [13,] 4.511038 4.377798
#> [14,] 4.223222 4.291853
#> [15,] 4.281276 4.217547
#> [16,] 4.561733 4.209490
#> GCGAGAACAACTTGAC-300.1.2 GCGAGAACACTTGGAT-300.1.2
#> [1,] 4.296272 4.334702
#> [2,] 4.320694 3.698973
#> [3,] 3.652956 3.873922
#> [4,] 3.818766 4.186858
#> [5,] 5.195373 4.752772
#> [6,] 3.870180 3.962628
#> [7,] 4.617609 4.820945
#> [8,] 4.755141 4.315400
#> [9,] 4.051414 4.106776
#> [10,] 3.956941 3.911704
#> [11,] 4.197943 3.952772
#> [12,] 3.875964 4.017248
#> [13,] 4.002571 4.407803
#> [14,] 4.578406 4.183573
#> [15,] 3.837404 3.906776
#> [16,] 4.605398 4.311294
#> GCGCAACAGCTAGGCA-300.1.2 GCGCAACCACCCAGTG-300.1.2
#> [1,] 4.326415 4.555745
#> [2,] 4.364151 3.922553
#> [3,] 4.041509 4.005106
#> [4,] 4.260377 4.080284
#> [5,] 4.311321 5.230922
#> [6,] 4.477358 4.149504
#> [7,] 4.279245 4.608794
#> [8,] 4.882075 4.312624
#> [9,] 4.564151 4.247943
#> [10,] 4.593396 3.894184
#> [11,] 4.514151 4.103546
#> [12,] 4.422642 3.999149
#> [13,] 4.248113 4.322553
#> [14,] 4.153774 4.143262
#> [15,] 4.021698 4.234610
#> [16,] 4.491509 4.576738
#> GCGCGATTCTGCAGTA-300.1.2 GCGGGTTTCCGCGTTT-300.1.2
#> [1,] 3.974222 4.787330
#> [2,] 4.468444 3.257919
#> [3,] 4.221333 3.735747
#> [4,] 4.134222 4.135747
#> [5,] 4.709333 5.466968
#> [6,] 3.994667 3.983710
#> [7,] 4.471111 5.119457
#> [8,] 4.599111 3.983710
#> [9,] 4.295111 4.133032
#> [10,] 4.078222 3.777376
#> [11,] 4.594667 3.966516
#> [12,] 3.994667 3.933937
#> [13,] 4.138667 4.123077
#> [14,] 4.529778 4.158371
#> [15,] 3.930667 3.832579
#> [16,] 4.575111 4.151131
#> GCTGCGACACGGCGTT-300.1.2 GCTGGGTAGATAGTCA-300.1.2
#> [1,] 4.650337 4.488560
#> [2,] 3.913043 3.885335
#> [3,] 4.287814 4.182917
#> [4,] 4.301898 4.180447
#> [5,] 4.740355 4.685517
#> [6,] 3.917942 4.036141
#> [7,] 4.014697 4.456838
#> [8,] 4.672994 4.370255
#> [9,] 4.172688 4.286271
#> [10,] 4.008573 4.099974
#> [11,] 4.152480 4.033541
#> [12,] 4.172076 4.309802
#> [13,] 4.703613 4.273661
#> [14,] 3.937538 4.192798
#> [15,] 4.099204 4.232189
#> [16,] 4.307410 4.169657
#> GCTTGAAGTAAGAGAG-300.1.2 GGAAAGCAGTCCGGTC-300.1.2
#> [1,] 4.570049 4.433290
#> [2,] 3.813875 4.069301
#> [3,] 4.134935 4.316710
#> [4,] 4.623260 3.988342
#> [5,] 4.808038 4.518135
#> [6,] 4.014818 4.074482
#> [7,] 4.602155 4.711140
#> [8,] 4.275258 4.377591
#> [9,] 4.198922 4.093912
#> [10,] 3.892905 3.893135
#> [11,] 4.154468 4.156736
#> [12,] 4.140323 3.778497
#> [13,] 4.155141 4.448834
#> [14,] 4.161428 4.210492
#> [15,] 4.022003 3.954016
#> [16,] 4.143467 4.201425
#> GGAAAGCCAGGCTGAA-300.1.2 GGAAAGCGTAGCCTCG-300.1.2
#> [1,] 4.709066 4.245075
#> [2,] 3.875578 4.301812
#> [3,] 4.072618 4.254531
#> [4,] 3.902868 4.111111
#> [5,] 5.324699 4.598897
#> [6,] 3.909343 4.090623
#> [7,] 4.944496 4.275020
#> [8,] 4.379741 4.578408
#> [9,] 4.190102 4.353034
#> [10,] 3.868178 4.069346
#> [11,] 4.262720 4.103231
#> [12,] 4.178538 4.089835
#> [13,] 4.081406 4.506698
#> [14,] 4.290472 4.301024
#> [15,] 4.010638 3.767533
#> [16,] 4.596207 4.805359
#> GGAACTTTCTTATCTG-300.1.2 GGAATAATCACGGTTA-300.1.2
#> [1,] 4.389279 4.409624
#> [2,] 3.780060 4.126174
#> [3,] 3.920842 4.434859
#> [4,] 4.214429 4.508803
#> [5,] 5.412826 4.869718
#> [6,] 3.948898 4.078638
#> [7,] 5.207415 4.644953
#> [8,] 4.332164 4.329225
#> [9,] 3.844689 4.284624
#> [10,] 4.045090 4.145540
#> [11,] 3.969940 4.093897
#> [12,] 3.849699 4.408451
#> [13,] 4.133267 4.308099
#> [14,] 4.500501 4.059859
#> [15,] 3.724950 4.210094
#> [16,] 3.956914 4.291080
#> GGACAAGGTCGCTTCT-300.1.2 GGACAGAGTAGCGTAG-300.1.2
#> [1,] 4.450980 4.561926
#> [2,] 3.787197 3.845740
#> [3,] 4.137255 4.230915
#> [4,] 4.155709 4.541653
#> [5,] 5.265859 4.735825
#> [6,] 3.871972 4.073804
#> [7,] 4.881200 4.434273
#> [8,] 4.016148 4.251821
#> [9,] 4.194925 4.448844
#> [10,] 3.817762 4.104213
#> [11,] 4.115917 4.081090
#> [12,] 3.803922 4.161863
#> [13,] 4.109573 4.348115
#> [14,] 4.232987 4.273361
#> [15,] 3.985006 3.981945
#> [16,] 4.303345 4.313272
#> GGACATTCATGTAAGA-300.1.2 GGCGACTGTTGTACAC-300.1.2
#> [1,] 4.545012 4.768836
#> [2,] 3.570316 3.627854
#> [3,] 3.762530 4.214041
#> [4,] 4.583942 4.263128
#> [5,] 4.795134 4.588470
#> [6,] 3.876399 4.146119
#> [7,] 5.035036 4.538813
#> [8,] 4.243309 4.462900
#> [9,] 4.159611 4.128425
#> [10,] 3.684672 4.036530
#> [11,] 3.983455 4.361301
#> [12,] 3.702190 4.200913
#> [13,] 4.304136 4.248858
#> [14,] 4.286131 4.224315
#> [15,] 3.624331 3.821347
#> [16,] 3.990754 4.047945
#> GGCTCGATCCACTCCA-300.1.2 GGCTGGTTCAGCTTAG-300.1.2
#> [1,] 4.217468 4.969343
#> [2,] 4.188159 3.697324
#> [3,] 4.276671 4.080779
#> [4,] 3.950762 4.239416
#> [5,] 4.594373 5.309002
#> [6,] 4.257913 3.879319
#> [7,] 4.276671 4.438443
#> [8,] 4.563306 4.275426
#> [9,] 4.577374 3.737226
#> [10,] 4.153576 3.812652
#> [11,] 4.188746 4.000487
#> [12,] 4.542204 3.804866
#> [13,] 4.388628 4.023358
#> [14,] 4.199297 4.287105
#> [15,] 4.260844 3.990268
#> [16,] 4.507034 4.651095
#> GGGAGATTCCGAACGC-300.1.2 GGGCACTTCGGAAATA-300.1.2
#> [1,] 4.411738 4.711064
#> [2,] 3.723521 3.618298
#> [3,] 3.997707 3.893191
#> [4,] 4.323246 4.044681
#> [5,] 4.981201 5.259149
#> [6,] 4.015589 3.960851
#> [7,] 4.890876 4.710638
#> [8,] 4.183402 4.119574
#> [9,] 3.935351 3.905532
#> [10,] 3.878496 3.918723
#> [11,] 4.006419 4.084255
#> [12,] 3.941311 3.937021
#> [13,] 4.343420 4.098723
#> [14,] 4.237964 4.390638
#> [15,] 3.975699 3.961277
#> [16,] 4.218707 4.390213
#> GGGTTGCGTCAATACC-300.1.2 GGTATTGAGAGTCGGT-300.1.2
#> [1,] 4.320020 4.791647
#> [2,] 4.467798 3.676678
#> [3,] 4.138293 3.882215
#> [4,] 4.067399 4.301736
#> [5,] 4.529206 5.352886
#> [6,] 4.083375 3.883153
#> [7,] 4.300549 4.717034
#> [8,] 4.517723 4.295167
#> [9,] 4.220669 3.811825
#> [10,] 4.121817 3.762553
#> [11,] 4.170744 4.112154
#> [12,] 3.889666 3.989207
#> [13,] 4.585122 4.107461
#> [14,] 4.099850 4.155795
#> [15,] 4.332501 3.996715
#> [16,] 4.520719 4.635382
#> GGTATTGAGAGTGAGA-300.1.2 GGTATTGCACGCGAAA-300.1.2
#> [1,] 4.346295 4.641674
#> [2,] 4.029427 3.565777
#> [3,] 3.882291 3.930083
#> [4,] 4.343142 4.629255
#> [5,] 4.819758 4.988040
#> [6,] 3.967945 3.912144
#> [7,] 5.046243 4.924563
#> [8,] 4.444561 4.169273
#> [9,] 4.181293 4.046918
#> [10,] 4.087231 3.823367
#> [11,] 4.261167 3.964581
#> [12,] 3.765633 3.863385
#> [13,] 4.231739 4.110856
#> [14,] 4.259065 4.167893
#> [15,] 3.823437 3.691352
#> [16,] 4.191802 3.954922
#> GGTGAAGGTGGGTATG-300.1.2 GGTGCGTGTAGCCTAT-300.1.2
#> [1,] 4.745533 4.628130
#> [2,] 3.611803 3.657585
#> [3,] 3.710883 3.916789
#> [4,] 4.266378 4.259205
#> [5,] 5.203573 4.967599
#> [6,] 4.155387 3.723122
#> [7,] 4.914997 4.891016
#> [8,] 4.226313 4.288660
#> [9,] 4.051976 4.205449
#> [10,] 3.662696 3.842415
#> [11,] 3.938820 4.037555
#> [12,] 3.895506 3.996318
#> [13,] 4.232269 4.086892
#> [14,] 4.309691 4.324742
#> [15,] 4.311316 3.932990
#> [16,] 4.391446 4.199558
#> GGTGTTACAACCGCCA-300.1.2 GGTGTTACATTAACCG-300.1.2
#> [1,] 4.612085 4.822440
#> [2,] 4.019940 3.851261
#> [3,] 4.198187 3.972723
#> [4,] 4.293656 4.218219
#> [5,] 4.740181 5.266083
#> [6,] 3.992749 4.124035
#> [7,] 4.508157 4.423572
#> [8,] 4.283384 4.353062
#> [9,] 3.848943 3.910962
#> [10,] 4.153474 3.843026
#> [11,] 3.875529 4.034483
#> [12,] 3.940785 4.036541
#> [13,] 4.114199 4.254761
#> [14,] 4.389124 4.211529
#> [15,] 4.207855 4.177046
#> [16,] 4.240483 4.509521
#> GTAACTGTCACTATTC-300.1.2 GTACTTTCATGGTCTA-300.1.2
#> [1,] 4.501185 4.321174
#> [2,] 3.828355 4.390569
#> [3,] 3.961119 4.346975
#> [4,] 4.027027 4.100534
#> [5,] 4.637269 4.860320
#> [6,] 4.113798 4.581851
#> [7,] 4.891418 4.407473
#> [8,] 4.366524 4.751779
#> [9,] 4.245614 4.988434
#> [10,] 4.009483 4.200178
#> [11,] 4.069227 4.282028
#> [12,] 3.684211 4.518683
#> [13,] 4.533428 4.806940
#> [14,] 4.052157 4.185053
#> [15,] 3.870081 4.121886
#> [16,] 4.252726 4.484875
#> GTAGTCACAGAAGCAC-300.1.2 GTATTCTTCGCGGATC-300.1.2
#> [1,] 4.443299 4.328474
#> [2,] 3.666848 4.075316
#> [3,] 3.723277 4.381681
#> [4,] 4.036896 4.394315
#> [5,] 5.518719 4.922255
#> [6,] 3.753120 4.049806
#> [7,] 5.246880 4.658892
#> [8,] 4.337493 4.496113
#> [9,] 3.887141 4.134840
#> [10,] 3.756918 4.097182
#> [11,] 4.064569 4.103013
#> [12,] 3.775909 4.233236
#> [13,] 4.109604 4.241983
#> [14,] 4.334238 4.121963
#> [15,] 3.864894 4.319485
#> [16,] 4.168747 4.220845
#> GTCAAGTGTCAAGCGA-300.1.2 GTCACAACAGGGCATA-300.1.2
#> [1,] 4.713060 4.503951
#> [2,] 4.018589 4.376646
#> [3,] 4.164919 4.266023
#> [4,] 4.135844 4.635645
#> [5,] 4.749762 4.865672
#> [6,] 4.026215 4.339772
#> [7,] 4.513346 4.187884
#> [8,] 4.685891 4.572432
#> [9,] 4.155863 4.649693
#> [10,] 3.784080 4.211589
#> [11,] 4.367493 4.546093
#> [12,] 4.188275 4.495171
#> [13,] 4.154909 4.595259
#> [14,] 4.118208 4.214223
#> [15,] 4.134414 4.438982
#> [16,] 4.403718 4.494293
#> GTCACGGCACACCGCA-300.1.2 GTCACGGGTCATCCCT-300.1.2
#> [1,] 4.609418 4.780260
#> [2,] 3.724654 3.467013
#> [3,] 4.126870 4.107013
#> [4,] 4.037119 4.063896
#> [5,] 4.940166 4.906494
#> [6,] 4.183380 4.049870
#> [7,] 4.566205 4.561558
#> [8,] 4.153463 4.129351
#> [9,] 4.212188 4.134545
#> [10,] 3.709695 3.903377
#> [11,] 4.424377 4.301299
#> [12,] 4.362327 4.322597
#> [13,] 4.383934 4.326753
#> [14,] 4.092521 4.153766
#> [15,] 3.863158 3.671688
#> [16,] 4.055402 3.790649
#> GTCCTCACAGTTCCCT-300.1.2 GTCTTCGAGGTGCTAG-300.1.2
#> [1,] 4.563830 4.175743
#> [2,] 4.209865 4.461634
#> [3,] 4.090909 4.199876
#> [4,] 4.460348 4.186881
#> [5,] 4.395551 4.461634
#> [6,] 4.220503 3.977723
#> [7,] 4.349130 4.133663
#> [8,] 4.451644 4.923267
#> [9,] 4.402321 4.430693
#> [10,] 4.256286 4.433787
#> [11,] 3.995164 4.446163
#> [12,] 4.421663 3.922030
#> [13,] 4.734043 4.249381
#> [14,] 4.116054 4.465347
#> [15,] 4.017408 4.053218
#> [16,] 4.258221 4.566213
#> GTGAAGGTCCCACTTG-300.1.2 GTGCAGCCAGGATCGA-300.1.2
#> [1,] 4.501859 4.471851
#> [2,] 3.892193 3.923187
#> [3,] 4.292618 4.109256
#> [4,] 4.028678 4.139790
#> [5,] 5.207116 5.337786
#> [6,] 4.002124 3.782204
#> [7,] 4.263409 5.114504
#> [8,] 4.711099 4.159113
#> [9,] 4.301115 4.248807
#> [10,] 4.071163 3.740458
#> [11,] 4.005842 4.114027
#> [12,] 3.968667 3.981155
#> [13,] 4.540096 4.272185
#> [14,] 4.197026 4.354246
#> [15,] 4.054169 3.754532
#> [16,] 4.709506 3.898616
#> GTGCGGTAGTAGGCCA-300.1.2 GTGCTTCAGAGGACGG-300.1.2
#> [1,] 4.178309 4.411800
#> [2,] 3.994485 3.831347
#> [3,] 4.445772 4.213349
#> [4,] 4.236213 4.258045
#> [5,] 4.427390 5.044100
#> [6,] 3.921875 3.856973
#> [7,] 4.476103 4.599523
#> [8,] 4.329044 4.342670
#> [9,] 4.585478 3.993445
#> [10,] 4.264706 3.802741
#> [11,] 4.374081 4.249106
#> [12,] 4.173713 4.138260
#> [13,] 4.129596 4.002980
#> [14,] 4.345588 4.150179
#> [15,] 4.059743 4.136472
#> [16,] 4.208640 4.475566
#> GTGCTTCTCAACGGCC-300.1.2 GTGGGTCAGCAACGGT-300.1.2
#> [1,] 5.025180 4.478455
#> [2,] 3.630010 4.199108
#> [3,] 3.922919 4.287519
#> [4,] 4.197842 4.351412
#> [5,] 5.155190 4.959881
#> [6,] 3.790339 4.250371
#> [7,] 4.197328 4.269688
#> [8,] 4.260534 4.415305
#> [9,] 3.893628 4.111441
#> [10,] 3.823227 4.061664
#> [11,] 4.041110 4.210996
#> [12,] 3.881295 4.381872
#> [13,] 4.155190 4.172363
#> [14,] 4.212230 4.127786
#> [15,] 4.171120 4.088410
#> [16,] 4.493320 4.046805
#> GTGGGTCGTTCCATGA-300.1.2 GTGTTAGCAATAGCAA-300.1.2
#> [1,] 4.419929 4.666050
#> [2,] 3.979241 3.802035
#> [3,] 4.157770 4.120259
#> [4,] 4.225979 4.084644
#> [5,] 5.196916 4.835800
#> [6,] 4.105575 4.235893
#> [7,] 4.755635 4.571693
#> [8,] 4.330368 4.348289
#> [9,] 4.161922 4.332562
#> [10,] 3.877817 3.988899
#> [11,] 3.959668 4.342276
#> [12,] 3.918149 4.151711
#> [13,] 4.353499 4.314524
#> [14,] 4.248517 4.145236
#> [15,] 4.193950 3.874653
#> [16,] 4.040925 4.023589
#> GTTAAGCAGAAGGTGA-300.1.2 GTTAAGCTCGTAGGAG-300.1.2
#> [1,] 4.807580 4.518824
#> [2,] 3.507289 3.962353
#> [3,] 4.117590 4.147059
#> [4,] 4.076288 4.298824
#> [5,] 4.899903 4.892353
#> [6,] 4.141885 3.942353
#> [7,] 4.862002 4.253529
#> [8,] 4.118562 4.352941
#> [9,] 4.205539 4.150000
#> [10,] 3.760447 4.125882
#> [11,] 4.392128 4.010588
#> [12,] 4.244898 4.361176
#> [13,] 4.342566 4.182941
#> [14,] 4.074830 4.200588
#> [15,] 3.870262 4.008824
#> [16,] 3.929057 3.964706
#> TAAGTGCAGCTAAACA-300.1.2 TACAGTGAGGCTAGCA-300.1.2
#> [1,] 4.603401 4.998234
#> [2,] 3.656061 3.623896
#> [3,] 3.911135 4.188935
#> [4,] 4.562260 4.600353
#> [5,] 4.806912 5.056504
#> [6,] 3.924849 3.818717
#> [7,] 5.069665 4.237198
#> [8,] 4.125617 4.600353
#> [9,] 3.950631 3.925839
#> [10,] 3.826111 3.672749
#> [11,] 4.125069 3.912890
#> [12,] 3.940208 3.642731
#> [13,] 4.177729 4.502060
#> [14,] 4.398793 3.827546
#> [15,] 3.763577 4.207769
#> [16,] 4.073505 4.243673
#> TACCTATCATCTGGTA-300.1.2 TACCTATTCAGCGATT-300.1.2
#> [1,] 4.923669 4.341249
#> [2,] 3.693393 4.013193
#> [3,] 3.978191 4.180739
#> [4,] 4.570237 4.200528
#> [5,] 4.720334 4.910290
#> [6,] 4.132777 4.059367
#> [7,] 4.069275 4.442832
#> [8,] 4.409878 4.482850
#> [9,] 4.110327 4.303430
#> [10,] 4.236049 3.950748
#> [11,] 3.871713 4.082674
#> [12,] 3.959589 4.323659
#> [13,] 4.008980 4.228232
#> [14,] 4.270045 4.214600
#> [15,] 4.067992 4.547493
#> [16,] 4.029506 4.439754
#> TACGGATTCCAAACTG-300.1.2 TACTTACAGTATCTCG-300.1.2
#> [1,] 4.780600 4.602707
#> [2,] 3.765589 3.547368
#> [3,] 4.200346 3.965414
#> [4,] 4.050808 4.030977
#> [5,] 4.976328 5.417744
#> [6,] 3.931871 3.956692
#> [7,] 4.178406 5.288120
#> [8,] 4.607390 3.826767
#> [9,] 4.042725 3.890226
#> [10,] 4.188222 3.936541
#> [11,] 4.267898 4.047218
#> [12,] 4.112587 3.934737
#> [13,] 4.363741 4.394586
#> [14,] 4.307737 4.271579
#> [15,] 4.183025 3.757594
#> [16,] 4.817552 3.697444
#> TACTTACTCTTCGAGA-300.1.2 TACTTGTCACACCGAC-300.1.2
#> [1,] 4.576646 4.536204
#> [2,] 3.897634 4.007045
#> [3,] 4.016975 4.067710
#> [4,] 4.483025 4.254403
#> [5,] 4.746399 5.187476
#> [6,] 3.864712 3.894325
#> [7,] 4.916667 4.918591
#> [8,] 4.385802 4.026614
#> [9,] 4.201646 4.329159
#> [10,] 3.861111 4.106067
#> [11,] 4.180556 4.207045
#> [12,] 3.851337 4.049706
#> [13,] 3.943416 4.313112
#> [14,] 4.136831 4.360078
#> [15,] 3.764918 3.882583
#> [16,] 4.107510 4.051663
#> TAGAGCTTCTTGACGA-300.1.2 TAGTGGTAGGATTCGG-300.1.2
#> [1,] 4.543739 4.728241
#> [2,] 3.666381 3.863889
#> [3,] 4.157804 3.790278
#> [4,] 4.464837 4.276852
#> [5,] 4.996569 5.352315
#> [6,] 3.830189 3.868056
#> [7,] 4.868782 4.883333
#> [8,] 4.198971 4.158796
#> [9,] 4.212693 4.130556
#> [10,] 4.028302 3.877778
#> [11,] 3.848199 4.097222
#> [12,] 4.144082 3.624537
#> [13,] 4.223842 4.096296
#> [14,] 4.182676 4.378704
#> [15,] 3.875643 3.893981
#> [16,] 4.180103 4.170833
#> TATCAGGAGCGATCCC-300.1.2 TATCAGGAGGGCACTA-300.1.2
#> [1,] 4.402661 4.425982
#> [2,] 3.903769 4.206445
#> [3,] 4.062084 4.463243
#> [4,] 3.991574 4.164149
#> [5,] 5.070510 4.343404
#> [6,] 4.266075 4.522659
#> [7,] 4.845233 4.461229
#> [8,] 4.375610 4.506546
#> [9,] 4.290909 4.397784
#> [10,] 4.049667 4.590131
#> [11,] 4.179157 4.175227
#> [12,] 4.178714 4.442095
#> [13,] 4.115743 4.242699
#> [14,] 4.172949 4.369587
#> [15,] 4.091796 4.425982
#> [16,] 4.500222 4.557905
#> TCAGATGCAGTTCCCT-300.1.2 TCAGCAACACAGATTC-300.1.2
#> [1,] 4.367189 4.838870
#> [2,] 4.032811 3.874070
#> [3,] 4.208568 4.309370
#> [4,] 4.286520 4.444224
#> [5,] 5.143783 4.999008
#> [6,] 4.113480 4.126425
#> [7,] 4.872518 4.632127
#> [8,] 4.424660 4.316807
#> [9,] 4.127900 4.527516
#> [10,] 4.041170 4.041150
#> [11,] 4.136886 4.028756
#> [12,] 4.188924 4.188894
#> [13,] 4.313062 4.349033
#> [14,] 4.350261 4.059494
#> [15,] 4.113689 3.917204
#> [16,] 4.157785 4.209717
#> TCAGCTCTCCAAAGTC-300.1.2 TCATTACGTTGAGGTG-300.1.2
#> [1,] 4.500951 4.697479
#> [2,] 3.869772 3.601774
#> [3,] 4.097909 4.178338
#> [4,] 4.038973 4.248833
#> [5,] 5.038973 4.798786
#> [6,] 3.933460 4.330532
#> [7,] 4.369772 4.573296
#> [8,] 4.479087 4.328198
#> [9,] 4.054183 4.048553
#> [10,] 3.961027 3.903828
#> [11,] 4.071293 4.406162
#> [12,] 4.247148 4.186275
#> [13,] 4.838403 4.250233
#> [14,] 4.040875 4.133987
#> [15,] 4.099810 3.887955
#> [16,] 4.275665 4.030345
#> TCATTTGTCTCTAAGG-300.1.2 TCATTTGTCTGCCCTA-300.1.2
#> [1,] 4.417687 4.662655
#> [2,] 3.852704 3.805901
#> [3,] 4.090529 4.142081
#> [4,] 4.094712 4.321817
#> [5,] 5.040633 4.814441
#> [6,] 3.858082 4.070264
#> [7,] 4.996116 4.674301
#> [8,] 4.222289 4.298525
#> [9,] 4.333732 4.071817
#> [10,] 3.847027 3.940994
#> [11,] 4.161040 4.284938
#> [12,] 4.119211 4.284550
#> [13,] 4.308037 4.228261
#> [14,] 4.350762 4.227484
#> [15,] 3.824320 3.998835
#> [16,] 3.861368 3.931289
#> TCCACACAGGACAGCT-300.1.2 TCCCGATCAGACGTAG-300.1.2
#> [1,] 4.495917 4.783162
#> [2,] 3.720196 3.668135
#> [3,] 3.886772 3.689672
#> [4,] 4.604790 4.081743
#> [5,] 4.949374 5.297602
#> [6,] 3.911268 3.851689
#> [7,] 5.046271 4.756241
#> [8,] 4.277082 4.096427
#> [9,] 4.188351 4.186980
#> [10,] 3.998911 3.826236
#> [11,] 4.008710 4.006363
#> [12,] 3.961350 3.950563
#> [13,] 4.124115 4.155653
#> [14,] 4.347850 4.418013
#> [15,] 3.793141 3.985805
#> [16,] 4.022319 4.398434
#> TCCCGATTCGGAAACG-300.1.2 TCGCGAGGTATCGCAT-300.1.2
#> [1,] 4.272727 4.624797
#> [2,] 3.971470 3.812128
#> [3,] 4.161025 3.962642
#> [4,] 4.071567 4.180292
#> [5,] 4.759188 5.283703
#> [6,] 4.236944 4.140227
#> [7,] 4.898453 5.112074
#> [8,] 4.323501 4.380617
#> [9,] 4.018375 4.331348
#> [10,] 4.113636 3.773687
#> [11,] 4.046422 4.171630
#> [12,] 4.391199 3.970222
#> [13,] 4.199710 4.128316
#> [14,] 4.057060 4.348132
#> [15,] 4.011122 3.870060
#> [16,] 4.325435 4.338928
#> TCGCGTTGTCGTCTTC-300.1.2 TCGTAGACAATCAGAA-300.1.2
#> [1,] 4.523736 4.491881
#> [2,] 4.179567 4.071042
#> [3,] 4.075335 4.014885
#> [4,] 4.289474 4.152233
#> [5,] 4.640867 4.832882
#> [6,] 4.310630 3.953992
#> [7,] 4.144995 4.438430
#> [8,] 4.650155 4.719215
#> [9,] 4.369453 4.503383
#> [10,] 4.371001 3.941137
#> [11,] 3.979360 4.338972
#> [12,] 4.509804 3.910014
#> [13,] 4.501548 3.875507
#> [14,] 4.117131 4.665088
#> [15,] 4.167183 3.778078
#> [16,] 4.605779 4.226658
#> TGACTAGCATGTTCCC-300.1.2 TGACTTTAGTTCCACA-300.1.2
#> [1,] 4.107143 4.791185
#> [2,] 3.593750 3.894766
#> [3,] 3.877480 4.082094
#> [4,] 4.308532 4.226997
#> [5,] 4.883433 5.029752
#> [6,] 3.911706 3.744353
#> [7,] 5.311508 4.418182
#> [8,] 4.246032 4.498623
#> [9,] 4.341766 4.251240
#> [10,] 4.020833 3.715152
#> [11,] 4.317956 4.053444
#> [12,] 4.096230 4.061157
#> [13,] 4.176587 4.455647
#> [14,] 4.416667 4.201653
#> [15,] 3.723710 4.236915
#> [16,] 4.156746 4.726722
#> TGAGAGGGTAAACACA-300.1.2 TGAGCCGAGTTCGCAT-300.1.2
#> [1,] 4.545251 4.674625
#> [2,] 4.198935 3.943365
#> [3,] 4.251891 4.245974
#> [4,] 4.293359 4.310383
#> [5,] 4.601289 4.590228
#> [6,] 4.593724 4.233759
#> [7,] 4.392827 4.344253
#> [8,] 5.115158 4.471405
#> [9,] 4.800504 4.310383
#> [10,] 4.204819 4.062188
#> [11,] 4.357803 4.289839
#> [12,] 4.580555 4.223765
#> [13,] 4.456150 4.392560
#> [14,] 4.320818 3.856746
#> [15,] 4.239283 4.033315
#> [16,] 4.719529 4.194336
#> TGAGCCGCAGCGAACA-300.1.2 TGAGCCGGTGAGTGAC-300.1.2
#> [1,] 4.463496 4.343037
#> [2,] 4.122473 4.321007
#> [3,] 4.315101 4.481511
#> [4,] 4.303924 4.061369
#> [5,] 4.775981 4.482297
#> [6,] 4.230916 4.323367
#> [7,] 4.681570 4.162864
#> [8,] 4.494174 4.446105
#> [9,] 4.424495 4.270653
#> [10,] 4.075862 4.453186
#> [11,] 4.424019 4.494099
#> [12,] 4.228775 4.344611
#> [13,] 4.172889 4.224233
#> [14,] 4.314150 4.118017
#> [15,] 4.053270 4.438238
#> [16,] 4.083710 4.549174
#> TGAGGGAGTCTAGTCA-300.1.2 TGATTTCAGCGTAATA-300.1.2
#> [1,] 4.191852 4.618103
#> [2,] 4.509711 3.686621
#> [3,] 4.179062 4.145691
#> [4,] 3.984368 4.091237
#> [5,] 4.651824 5.401731
#> [6,] 3.715301 3.824017
#> [7,] 4.231170 4.809232
#> [8,] 4.976315 3.962135
#> [9,] 4.513501 3.894699
#> [10,] 4.175272 3.846015
#> [11,] 4.432496 4.125496
#> [12,] 4.443865 4.257122
#> [13,] 4.483657 4.328525
#> [14,] 4.455234 4.441760
#> [15,] 4.232591 4.149297
#> [16,] 4.350071 4.104580
#> TGCACCTAGCGATATA-300.1.2 TGCACCTAGTTGTCGT-300.1.2
#> [1,] 4.479607 4.355253
#> [2,] 3.920393 4.408180
#> [3,] 4.054545 4.516439
#> [4,] 4.211302 4.266239
#> [5,] 5.083538 4.619888
#> [6,] 4.018673 4.241379
#> [7,] 4.692383 4.411387
#> [8,] 4.345946 4.441860
#> [9,] 4.019656 4.587009
#> [10,] 3.864865 4.457899
#> [11,] 3.806880 4.053729
#> [12,] 4.007862 4.550922
#> [13,] 4.371990 4.376103
#> [14,] 4.120885 4.085806
#> [15,] 4.128256 4.097033
#> [16,] 4.225061 4.474739
#> TGCACCTAGTTTGCGT-300.1.2 TGCTACCGTGGACGAT-300.1.2
#> [1,] 4.574451 4.478438
#> [2,] 3.776646 3.907925
#> [3,] 4.068182 4.026807
#> [4,] 4.038401 4.316434
#> [5,] 4.728840 4.751166
#> [6,] 4.370690 4.403846
#> [7,] 4.692006 4.576340
#> [8,] 4.025078 4.367716
#> [9,] 4.264890 4.188228
#> [10,] 4.130094 4.183566
#> [11,] 4.345611 4.047786
#> [12,] 4.369906 4.035548
#> [13,] 4.198276 4.469114
#> [14,] 4.170846 4.210373
#> [15,] 3.914577 4.011072
#> [16,] 4.327586 4.115385
#> TGCTACCTCAACACCA-300.1.2 TGGGCGTTCAGATAAG-300.1.2
#> [1,] 4.641609 4.419486
#> [2,] 3.756485 3.956022
#> [3,] 3.874007 4.042625
#> [4,] 4.622022 4.060893
#> [5,] 4.606670 4.994587
#> [6,] 3.761779 3.912720
#> [7,] 5.135521 4.522327
#> [8,] 4.213340 4.338972
#> [9,] 4.227634 4.125846
#> [10,] 3.797247 3.845737
#> [11,] 4.014823 4.033153
#> [12,] 4.038115 4.054127
#> [13,] 4.149285 4.208390
#> [14,] 4.354685 4.588633
#> [15,] 3.774484 3.866712
#> [16,] 3.960296 4.519621
#> TGGTTAGCATATACCG-300.1.2 TGGTTAGGTTATGTGC-300.1.2
#> [1,] 4.335931 4.664444
#> [2,] 3.960829 4.084619
#> [3,] 4.089418 4.037516
#> [4,] 4.209598 4.129637
#> [5,] 5.006358 5.107545
#> [6,] 3.971288 4.090454
#> [7,] 4.857670 5.040017
#> [8,] 4.338802 4.403918
#> [9,] 4.142740 3.902459
#> [10,] 4.038556 3.967070
#> [11,] 4.127564 4.061276
#> [12,] 4.057629 4.062109
#> [13,] 4.167145 4.205085
#> [14,] 4.406686 4.200917
#> [15,] 3.922067 3.822426
#> [16,] 4.107055 3.746144
#> TGTCCCATCTCCAGGG-300.1.2 TGTGTTTGTAATTGGA-300.1.2
#> [1,] 4.454948 4.625114
#> [2,] 4.268833 3.720548
#> [3,] 4.077548 4.141096
#> [4,] 4.033235 4.094521
#> [5,] 4.710487 5.054338
#> [6,] 4.207533 4.111416
#> [7,] 4.284343 4.882648
#> [8,] 4.476366 4.207306
#> [9,] 4.389217 3.972603
#> [10,] 4.275480 3.984475
#> [11,] 3.905465 4.112785
#> [12,] 4.241507 4.076256
#> [13,] 4.557607 4.318721
#> [14,] 4.062038 4.111416
#> [15,] 4.191285 3.977626
#> [16,] 4.640325 3.983105
#> TGTGTTTGTCGCGTGT-300.1.2 TGTTCCGTCATCTGTT-300.1.2
#> [1,] 4.206545 5.023410
#> [2,] 4.314909 3.478372
#> [3,] 4.330182 3.753181
#> [4,] 4.147636 4.312977
#> [5,] 4.559273 5.100763
#> [6,] 4.158545 3.981170
#> [7,] 4.172364 4.728244
#> [8,] 4.473455 3.991858
#> [9,] 4.218182 3.966921
#> [10,] 4.291636 3.548601
#> [11,] 4.163636 4.161323
#> [12,] 4.393455 3.865140
#> [13,] 4.346182 4.074300
#> [14,] 4.087273 4.256997
#> [15,] 4.121455 3.617812
#> [16,] 4.464727 4.050891
#> TTATGCTAGGACAGCT-300.1.2 TTCCCAGAGCTATGCT-300.1.2
#> [1,] 4.281530 4.435336
#> [2,] 3.775427 3.992933
#> [3,] 3.782750 3.945583
#> [4,] 3.764849 4.236749
#> [5,] 5.127746 5.353357
#> [6,] 3.833198 3.936396
#> [7,] 4.891782 5.120141
#> [8,] 4.245728 4.316608
#> [9,] 4.388934 4.072085
#> [10,] 3.571196 3.686219
#> [11,] 4.045566 4.230389
#> [12,] 3.833198 3.964664
#> [13,] 4.021155 4.228269
#> [14,] 4.738812 4.501060
#> [15,] 3.889341 3.736396
#> [16,] 3.988609 4.185866
#> TTCGAAGGTTGCCTCT-300.1.2 TTCTCAATCCGTACAA-300.1.2
#> [1,] 4.316904 4.259259
#> [2,] 3.792910 3.960969
#> [3,] 3.917423 4.272080
#> [4,] 4.261133 4.168946
#> [5,] 4.964116 4.924501
#> [6,] 3.985733 3.945014
#> [7,] 4.958928 4.787464
#> [8,] 4.306528 4.267521
#> [9,] 4.140078 4.274074
#> [10,] 3.933852 4.007407
#> [11,] 4.156074 4.130484
#> [12,] 3.786425 4.233618
#> [13,] 4.300476 4.347578
#> [14,] 4.311284 4.425641
#> [15,] 3.763943 3.997151
#> [16,] 4.110679 4.256410
#> TTCTCCTAGTACGATA-300.1.2 TTCTTAGCACGCATCG-300.1.2
#> [1,] 4.397403 4.441228
#> [2,] 4.314286 4.099016
#> [3,] 3.802597 4.211928
#> [4,] 4.298701 4.232774
#> [5,] 4.393939 4.725536
#> [6,] 4.553247 3.900405
#> [7,] 4.635498 4.182976
#> [8,] 4.945455 4.696584
#> [9,] 4.804329 4.237406
#> [10,] 4.104762 3.985524
#> [11,] 4.231169 4.277939
#> [12,] 4.635498 4.046323
#> [13,] 4.635498 4.160394
#> [14,] 4.196537 4.367690
#> [15,] 3.899567 4.086277
#> [16,] 4.580952 4.753329
#> TTGAACGCAGGGTACA-300.1.2 TTGACTTAGCGTGTCC-300.1.2
#> [1,] 4.228723 4.606376
#> [2,] 4.003546 3.852851
#> [3,] 3.896720 4.008584
#> [4,] 3.965869 4.115880
#> [5,] 5.304965 5.312692
#> [6,] 4.126773 3.906806
#> [7,] 5.098848 4.876763
#> [8,] 4.562057 4.301042
#> [9,] 4.118794 3.982833
#> [10,] 3.872340 3.854077
#> [11,] 4.247340 4.095034
#> [12,] 4.035461 3.958308
#> [13,] 4.259309 4.088903
#> [14,] 4.370567 4.130595
#> [15,] 3.826684 4.160638
#> [16,] 4.164450 4.346413
#> TTGACTTCACGAGAGT-300.1.2 TTGCCGTCAAACGTGG-300.1.2
#> [1,] 3.882314 4.728509
#> [2,] 4.101667 3.908694
#> [3,] 3.701210 4.125304
#> [4,] 3.836221 4.233123
#> [5,] 5.367440 5.112676
#> [6,] 3.829356 4.101506
#> [7,] 5.411899 4.690627
#> [8,] 4.402746 4.416221
#> [9,] 3.859758 4.120932
#> [10,] 4.031383 4.144245
#> [11,] 4.290618 4.195240
#> [12,] 3.824452 3.946090
#> [13,] 4.031383 4.189898
#> [14,] 4.499510 4.070423
#> [15,] 3.747303 3.997572
#> [16,] 3.830991 4.364254
#> TTGCGTCGTAGCGCTC-300.1.2 TTTATGCCATATACGC-300.1.2
#> [1,] 4.367787 4.302663
#> [2,] 3.658806 4.046547
#> [3,] 3.644255 4.052825
#> [4,] 4.205218 4.327777
#> [5,] 5.702459 5.050011
#> [6,] 3.708480 4.015588
#> [7,] 5.274461 5.146136
#> [8,] 4.000502 4.299848
#> [9,] 3.786252 4.253302
#> [10,] 3.584044 4.020351
#> [11,] 4.000502 4.115609
#> [12,] 3.830406 3.953670
#> [13,] 4.212745 4.264343
#> [14,] 4.298043 4.440139
#> [15,] 3.877572 3.904308
#> [16,] 4.053688 3.954103
#> TTTCCTCTCTCTTATG-300.1.2 TTTGGTTGTTGATTGC-300.1.2
#> [1,] 4.514271 4.320158
#> [2,] 3.645969 4.169302
#> [3,] 3.887331 4.133729
#> [4,] 4.162243 4.262846
#> [5,] 5.065598 4.386693
#> [6,] 4.157737 4.140316
#> [7,] 4.836755 4.223320
#> [8,] 4.364046 4.371542
#> [9,] 4.371057 4.307642
#> [10,] 4.040060 4.002635
#> [11,] 4.080621 3.947299
#> [12,] 4.092138 4.066535
#> [13,] 4.029044 4.287220
#> [14,] 4.271407 4.162055
#> [15,] 3.880320 4.282609
#> [16,] 4.061592 4.422266
#> AAAGATGTCGATCCCT-300.1.3 AAAGCAAGTAGGAGTC-300.1.3
#> [1,] 4.391143 4.884045
#> [2,] 3.716631 3.972973
#> [3,] 4.149272 4.404534
#> [4,] 4.353670 4.830863
#> [5,] 5.123258 4.600697
#> [6,] 3.929080 4.047079
#> [7,] 5.119542 4.480384
#> [8,] 4.371942 4.376635
#> [9,] 4.000310 4.411508
#> [10,] 3.869309 4.292938
#> [11,] 4.191081 4.374019
#> [12,] 4.077733 4.118570
#> [13,] 4.067203 3.917175
#> [14,] 4.273459 4.401046
#> [15,] 3.810468 4.149085
#> [16,] 4.020749 4.315606
#> AAATGCCAGAAGGTGA-300.1.3 AACCATGGTGCAGTAG-300.1.3
#> [1,] 4.299224 4.654581
#> [2,] 3.677498 4.196440
#> [3,] 4.182832 4.280817
#> [4,] 4.075170 4.174028
#> [5,] 5.368574 4.916282
#> [6,] 3.746848 3.985498
#> [7,] 5.129971 4.090969
#> [8,] 3.991756 4.785102
#> [9,] 3.899127 4.131180
#> [10,] 4.130456 3.839815
#> [11,] 4.129971 4.280158
#> [12,] 4.232299 4.158207
#> [13,] 4.245878 4.398813
#> [14,] 4.245878 3.798945
#> [15,] 3.763822 4.152933
#> [16,] 4.181862 4.543177
#> AACGTTGGTTGAGGTG-300.1.3 AACTCCCAGAAACCAT-300.1.3
#> [1,] 4.221217 4.546106
#> [2,] 4.218200 3.645031
#> [3,] 4.292107 3.863026
#> [4,] 4.216189 4.144584
#> [5,] 4.634992 5.503581
#> [6,] 4.121669 3.944047
#> [7,] 4.039718 5.103850
#> [8,] 4.689291 4.102954
#> [9,] 4.581699 3.979857
#> [10,] 4.334842 3.768129
#> [11,] 4.178482 3.957028
#> [12,] 4.543992 3.967771
#> [13,] 4.573655 4.233662
#> [14,] 4.058321 4.223814
#> [15,] 4.150830 4.110116
#> [16,] 4.518854 4.352731
#> AACTCCCCACTAAGTC-300.1.3 AACTGGTAGGACACCA-300.1.3
#> [1,] 4.261795 4.410394
#> [2,] 4.291397 3.920630
#> [3,] 4.123034 4.164724
#> [4,] 4.176688 4.423937
#> [5,] 4.327475 5.148661
#> [6,] 4.276596 3.974488
#> [7,] 4.341351 4.890079
#> [8,] 4.666050 4.128504
#> [9,] 4.283996 4.093858
#> [10,] 4.370028 3.912441
#> [11,] 4.318224 4.248189
#> [12,] 4.177613 4.168819
#> [13,] 4.673451 4.249134
#> [14,] 4.168363 4.195276
#> [15,] 4.145236 4.104252
#> [16,] 4.373728 4.375433
#> AACTGGTGTAGCCTCG-300.1.3 AACTGGTGTCTTCTCG-300.1.3
#> [1,] 4.544248 4.407857
#> [2,] 3.481748 4.139804
#> [3,] 3.924502 3.989601
#> [4,] 4.162887 4.266898
#> [5,] 5.224834 4.720393
#> [6,] 3.900166 4.063547
#> [7,] 5.176438 4.424610
#> [8,] 4.018529 4.471404
#> [9,] 3.831029 4.031196
#> [10,] 3.735066 3.985557
#> [11,] 4.109237 3.898325
#> [12,] 4.039270 4.001733
#> [13,] 4.368086 4.422877
#> [14,] 4.099004 4.062392
#> [15,] 3.794248 3.942230
#> [16,] 3.906250 4.347198
#> AAGCCGCGTTACGACT-300.1.3 AAGGAGCTCAGTTTGG-300.1.3
#> [1,] 4.574268 4.401742
#> [2,] 3.916841 4.259120
#> [3,] 4.257322 4.265004
#> [4,] 4.399059 4.277712
#> [5,] 4.753661 4.512120
#> [6,] 3.980126 4.269946
#> [7,] 4.690900 4.246411
#> [8,] 4.127615 4.867263
#> [9,] 4.186192 4.678748
#> [10,] 4.054916 4.376559
#> [11,] 4.244770 4.373970
#> [12,] 3.882845 4.536832
#> [13,] 4.268305 4.504354
#> [14,] 4.397490 4.269946
#> [15,] 4.129184 4.301483
#> [16,] 3.978033 4.521770
#> AAGTCTGTCGTAGGTT-300.1.3 AATCCAGGTCCAGTAT-300.1.3
#> [1,] 4.340633 4.467751
#> [2,] 4.087591 3.282394
#> [3,] 4.288929 3.786752
#> [4,] 4.357664 4.309704
#> [5,] 4.686131 5.038350
#> [6,] 4.172141 3.599651
#> [7,] 4.277372 4.958745
#> [8,] 4.548662 4.029634
#> [9,] 4.297445 4.324811
#> [10,] 4.201338 3.606043
#> [11,] 3.934915 4.034282
#> [12,] 4.153893 3.983149
#> [13,] 4.489659 4.290529
#> [14,] 4.128345 4.364323
#> [15,] 4.086983 3.785590
#> [16,] 4.530414 3.961650
#> AATCGGTAGAAGCCCA-300.1.3 ACACTGAGTTCAGTAC-300.1.3
#> [1,] 4.404470 4.367432
#> [2,] 3.878127 3.618998
#> [3,] 4.210218 3.873695
#> [4,] 3.996807 4.621086
#> [5,] 4.924960 4.825157
#> [6,] 4.110697 3.836117
#> [7,] 4.977115 5.003132
#> [8,] 4.522086 4.141441
#> [9,] 4.364023 4.025574
#> [10,] 4.246940 3.811065
#> [11,] 4.382650 4.044885
#> [12,] 4.119212 3.710334
#> [13,] 4.141565 4.212422
#> [14,] 4.361362 4.337161
#> [15,] 3.804151 3.661795
#> [16,] 4.188398 3.986430
#> ACATACGTCTTGTCAT-300.1.3 ACGAGGACAACTTGAC-300.1.3
#> [1,] 4.391513 4.420918
#> [2,] 3.880903 4.316327
#> [3,] 4.390828 4.155612
#> [4,] 4.229295 4.054209
#> [5,] 4.402464 4.614796
#> [6,] 4.447639 3.882015
#> [7,] 4.353867 3.911990
#> [8,] 4.546886 4.897321
#> [9,] 4.086927 4.196429
#> [10,] 4.262149 4.068240
#> [11,] 4.469541 4.357143
#> [12,] 4.561259 3.949617
#> [13,] 4.375770 4.410077
#> [14,] 4.036277 4.262117
#> [15,] 4.028747 4.062500
#> [16,] 4.331280 4.301020
#> ACGAGGACATCCAACA-300.1.3 ACGAGGAGTCATATCG-300.1.3
#> [1,] 4.278853 4.421053
#> [2,] 4.524731 4.103314
#> [3,] 4.460215 4.386940
#> [4,] 4.427240 4.270955
#> [5,] 4.558423 4.431774
#> [6,] 4.405735 4.269006
#> [7,] 3.997849 4.491228
#> [8,] 5.006452 4.658869
#> [9,] 5.141219 4.444444
#> [10,] 4.105376 4.463938
#> [11,] 4.065233 4.212476
#> [12,] 4.633692 4.285575
#> [13,] 4.530466 4.459064
#> [14,] 4.391398 4.131579
#> [15,] 4.216487 4.652047
#> [16,] 4.774910 4.863548
#> ACGGAGAAGAAAGTGG-300.1.3 ACGGAGACATCCAACA-300.1.3
#> [1,] 4.800514 4.212963
#> [2,] 4.009254 3.923002
#> [3,] 4.098715 4.216862
#> [4,] 4.326992 4.244639
#> [5,] 5.143959 4.820175
#> [6,] 3.945501 3.931774
#> [7,] 4.353213 5.142788
#> [8,] 4.459126 4.446881
#> [9,] 3.893573 4.168129
#> [10,] 3.981491 3.994152
#> [11,] 4.224679 4.280214
#> [12,] 3.961440 3.950780
#> [13,] 4.084833 4.187135
#> [14,] 3.969666 4.280702
#> [15,] 4.311568 4.204191
#> [16,] 4.575321 4.168129
#> ACGGCCACAGGACGTA-300.1.3 ACGGGCTCAGCTTAAC-300.1.3
#> [1,] 4.530443 4.533715
#> [2,] 3.805351 3.938931
#> [3,] 3.661439 4.042621
#> [4,] 4.030443 4.198473
#> [5,] 5.200185 4.975827
#> [6,] 3.631919 3.863232
#> [7,] 4.642989 4.160305
#> [8,] 4.495387 4.699746
#> [9,] 3.964022 4.160941
#> [10,] 3.750923 3.797074
#> [11,] 4.293358 4.108142
#> [12,] 3.775830 3.615140
#> [13,] 3.981550 4.424936
#> [14,] 4.317343 4.100509
#> [15,] 3.893911 4.151399
#> [16,] 3.978782 4.370865
#> ACGGGCTTCTACTATC-300.1.3 ACGTCAAAGCCCAATT-300.1.3
#> [1,] 4.693841 4.577759
#> [2,] 3.617150 3.856187
#> [3,] 3.827295 3.920569
#> [4,] 3.961353 4.164298
#> [5,] 5.440821 4.886288
#> [6,] 3.884058 3.957776
#> [7,] 5.062802 4.983278
#> [8,] 4.283213 4.296823
#> [9,] 3.995773 4.518813
#> [10,] 3.671498 4.069398
#> [11,] 4.032005 4.191054
#> [12,] 3.882850 3.964883
#> [13,] 4.077899 4.321906
#> [14,] 4.347222 4.315635
#> [15,] 4.207126 3.918896
#> [16,] 4.599638 4.086120
#> ACGTCAACAGGGTTAG-300.1.3 ACTGAGTCATAGTAAG-300.1.3
#> [1,] 4.496264 4.331726
#> [2,] 4.182759 3.458735
#> [3,] 4.180747 3.848339
#> [4,] 4.292816 4.352090
#> [5,] 4.537356 4.816184
#> [6,] 4.224138 3.801179
#> [7,] 4.450000 5.164523
#> [8,] 4.379023 4.372454
#> [9,] 4.364655 4.279743
#> [10,] 4.289368 3.663987
#> [11,] 4.153736 3.862808
#> [12,] 4.229310 3.759378
#> [13,] 4.268966 4.154341
#> [14,] 4.313793 4.482315
#> [15,] 4.167241 3.709003
#> [16,] 4.389080 4.235798
#> ACTGCTCCAGGGTACA-300.1.3 ACTGTCCAGTACGATA-300.1.3
#> [1,] 4.839763 4.491840
#> [2,] 4.004946 3.735163
#> [3,] 4.128091 4.224777
#> [4,] 4.555391 3.991840
#> [5,] 4.962908 5.000742
#> [6,] 4.000000 3.984421
#> [7,] 4.786350 4.868694
#> [8,] 4.172601 4.132047
#> [9,] 4.234916 3.943620
#> [10,] 3.775470 3.804154
#> [11,] 4.135015 4.448071
#> [12,] 4.148368 4.423591
#> [13,] 4.172601 4.263353
#> [14,] 4.045005 4.182493
#> [15,] 3.983680 3.902077
#> [16,] 3.954500 4.220326
#> ACTTGTTCAATGGTCT-300.1.3 AGACGTTGTCCTGCTT-300.1.3
#> [1,] 4.621774 4.163689
#> [2,] 3.666935 3.895101
#> [3,] 3.760484 4.013256
#> [4,] 4.008871 4.582133
#> [5,] 5.439516 4.790202
#> [6,] 3.797581 3.964841
#> [7,] 4.987097 4.937752
#> [8,] 4.073387 4.118732
#> [9,] 3.880645 4.059942
#> [10,] 3.570968 4.195965
#> [11,] 3.797581 4.303170
#> [12,] 3.766129 3.891643
#> [13,] 4.052419 4.221326
#> [14,] 4.230645 4.336023
#> [15,] 4.134677 3.794236
#> [16,] 4.366129 3.979827
#> AGAGCGAAGGGTCGAT-300.1.3 AGAGCTTAGTAGCGGT-300.1.3
#> [1,] 4.004225 4.476309
#> [2,] 3.806573 3.983541
#> [3,] 4.194836 4.264339
#> [4,] 4.010798 4.286783
#> [5,] 5.356338 4.757606
#> [6,] 4.209390 3.935162
#> [7,] 4.971362 4.659352
#> [8,] 4.122535 4.184539
#> [9,] 4.211268 4.052868
#> [10,] 4.146009 4.214963
#> [11,] 4.208451 3.980549
#> [12,] 4.089671 4.210973
#> [13,] 4.231925 4.118703
#> [14,] 4.463850 3.991521
#> [15,] 3.915962 4.541147
#> [16,] 3.995775 4.519202
#> AGAGCTTCAATGGAAT-300.1.3 AGATTGCAGTGCCAGA-300.1.3
#> [1,] 4.339376 4.558914
#> [2,] 4.236553 3.968750
#> [3,] 4.094205 4.314037
#> [4,] 4.220505 4.183914
#> [5,] 5.199406 4.615266
#> [6,] 4.182467 4.133709
#> [7,] 5.030906 4.286885
#> [8,] 4.269837 4.439037
#> [9,] 4.196434 4.244877
#> [10,] 4.229421 4.247951
#> [11,] 4.454086 4.031762
#> [12,] 3.909955 4.136270
#> [13,] 4.464487 4.290984
#> [14,] 4.531947 4.290984
#> [15,] 3.818722 4.205943
#> [16,] 4.040713 4.023053
#> AGATTGCGTTATGCGT-300.1.3 AGCGGTCTCCTTTACA-300.1.3
#> [1,] 4.223811 4.629973
#> [2,] 4.272032 4.190981
#> [3,] 4.438311 4.087533
#> [4,] 4.096442 4.235411
#> [5,] 4.977719 4.888594
#> [6,] 4.082474 4.037135
#> [7,] 4.810110 4.568302
#> [8,] 4.509810 4.291777
#> [9,] 4.295976 4.094828
#> [10,] 4.168607 4.169761
#> [11,] 4.427669 4.296419
#> [12,] 4.128035 4.068966
#> [13,] 4.220153 4.228780
#> [14,] 4.557034 4.303050
#> [15,] 3.978051 4.155172
#> [16,] 4.132690 4.332891
#> AGCGTCGCATATGCTG-300.1.3 AGCTCTCAGACACGAC-300.1.3
#> [1,] 4.339391 4.372449
#> [2,] 4.043713 4.620536
#> [3,] 4.361493 4.283163
#> [4,] 4.305992 4.086735
#> [5,] 4.432711 4.540179
#> [6,] 4.004912 4.083546
#> [7,] 4.844794 3.885204
#> [8,] 4.462181 4.978954
#> [9,] 4.134578 4.408163
#> [10,] 4.212672 4.360332
#> [11,] 4.233792 4.364796
#> [12,] 4.573183 4.357143
#> [13,] 4.319253 4.440051
#> [14,] 3.863949 4.392857
#> [15,] 4.108055 4.044643
#> [16,] 4.441552 4.380740
#> AGCTTGAGTGGCAAAC-300.1.3 AGGCCACGTCTTGATG-300.1.3
#> [1,] 4.681011 4.313002
#> [2,] 3.616803 4.257624
#> [3,] 3.771175 4.247191
#> [4,] 4.082650 4.515249
#> [5,] 5.032787 4.586677
#> [6,] 3.806011 4.454254
#> [7,] 5.011612 4.427769
#> [8,] 3.971995 4.742376
#> [9,] 4.303962 4.410112
#> [10,] 3.752732 4.412520
#> [11,] 3.628415 4.418138
#> [12,] 3.827869 4.529695
#> [13,] 4.437842 4.389246
#> [14,] 4.338798 4.188604
#> [15,] 3.898907 4.095506
#> [16,] 4.067623 4.532905
#> AGGCCGTGTGGAAAGA-300.1.3 AGGCCGTTCAGTACGT-300.1.3
#> [1,] 4.955224 4.695579
#> [2,] 3.504018 3.505684
#> [3,] 4.154994 3.754947
#> [4,] 4.458668 4.222316
#> [5,] 5.268083 5.314526
#> [6,] 3.645809 4.009263
#> [7,] 4.695178 4.922105
#> [8,] 4.605052 4.041684
#> [9,] 4.008611 3.949474
#> [10,] 3.804248 3.797053
#> [11,] 4.216992 3.983579
#> [12,] 3.846728 3.814737
#> [13,] 4.167049 4.021474
#> [14,] 4.028703 4.140211
#> [15,] 4.195178 3.974316
#> [16,] 4.604478 4.143579
#> AGTCTTTAGTGTACGG-300.1.3 AGTGTCACACAGCCCA-300.1.3
#> [1,] 4.621784 4.510471
#> [2,] 4.032293 4.244328
#> [3,] 4.157635 4.507853
#> [4,] 4.182813 4.231239
#> [5,] 4.644226 4.831588
#> [6,] 4.112753 4.714660
#> [7,] 4.246853 4.294066
#> [8,] 4.425287 5.147469
#> [9,] 4.404488 4.728621
#> [10,] 3.931582 4.414485
#> [11,] 4.386426 4.408377
#> [12,] 4.362343 4.718150
#> [13,] 4.429666 4.252182
#> [14,] 4.197592 4.327225
#> [15,] 4.133552 3.973822
#> [16,] 4.538041 4.330716
#> ATAAGAGTCCCACTTG-300.1.3 ATAGACCTCTAACGGT-300.1.3
#> [1,] 4.669401 4.280477
#> [2,] 4.023790 3.867008
#> [3,] 3.906481 3.957374
#> [4,] 4.448728 4.148764
#> [5,] 4.744053 5.461211
#> [6,] 3.982773 4.135976
#> [7,] 4.345365 5.286019
#> [8,] 4.360952 4.117647
#> [9,] 4.208368 4.124893
#> [10,] 3.808860 4.064791
#> [11,] 3.696473 4.141517
#> [12,] 3.972108 4.061381
#> [13,] 4.666120 4.407502
#> [14,] 3.943396 4.255328
#> [15,] 4.068089 3.868286
#> [16,] 4.542248 4.038363
#> ATCATCTCATCACGTA-300.1.3 ATCATGGTCTGAAAGA-300.1.3
#> [1,] 4.046703 4.476360
#> [2,] 4.197802 3.861210
#> [3,] 4.267582 4.066090
#> [4,] 4.098901 4.164209
#> [5,] 4.528571 5.054906
#> [6,] 4.233516 3.875953
#> [7,] 4.619231 4.895272
#> [8,] 4.431319 4.293340
#> [9,] 4.278022 3.756990
#> [10,] 4.285165 3.832232
#> [11,] 4.193407 3.918658
#> [12,] 4.124725 3.983732
#> [13,] 4.239011 4.175394
#> [14,] 4.539011 4.260803
#> [15,] 4.163736 4.232842
#> [16,] 4.195604 4.274021
#> ATCATGGTCTGAGTGT-300.1.3 ATCCGAAAGCGTCTAT-300.1.3
#> [1,] 4.420518 4.480920
#> [2,] 3.777552 3.737374
#> [3,] 3.871508 3.968575
#> [4,] 4.274251 4.454545
#> [5,] 4.873540 5.001122
#> [6,] 4.035551 3.948373
#> [7,] 4.814119 5.135802
#> [8,] 4.197562 4.312570
#> [9,] 4.107669 4.122334
#> [10,] 4.027933 4.101010
#> [11,] 4.088878 4.142536
#> [12,] 3.865414 3.831089
#> [13,] 4.299644 4.359147
#> [14,] 4.498730 4.189113
#> [15,] 3.686643 3.811448
#> [16,] 4.032504 3.976431
#> ATCCGAACATTGGGCC-300.1.3 ATCTACTTCAACCATG-300.1.3
#> [1,] 4.424069 4.832425
#> [2,] 3.764327 3.508178
#> [3,] 4.148281 4.016356
#> [4,] 4.768625 4.247920
#> [5,] 4.910458 4.796844
#> [6,] 4.065186 4.102152
#> [7,] 4.983524 4.810904
#> [8,] 4.282951 4.150359
#> [9,] 4.145415 4.241320
#> [10,] 4.195559 3.788522
#> [11,] 4.337393 4.235294
#> [12,] 4.032951 4.167862
#> [13,] 4.242837 4.256241
#> [14,] 4.109599 4.229842
#> [15,] 3.887536 4.093831
#> [16,] 4.083811 3.993113
#> ATCTGCCAGCCAGAAC-300.1.3 ATCTGCCCAATGGTCT-300.1.3
#> [1,] 4.518482 4.422584
#> [2,] 3.742238 4.082840
#> [3,] 3.799409 4.053748
#> [4,] 4.235584 4.105030
#> [5,] 5.195663 5.212032
#> [6,] 3.757516 4.111933
#> [7,] 4.917201 5.162722
#> [8,] 3.952193 4.097140
#> [9,] 4.057171 4.212525
#> [10,] 3.695416 3.912229
#> [11,] 3.659931 3.927022
#> [12,] 3.908329 3.947732
#> [13,] 4.274027 4.279586
#> [14,] 4.127649 4.432446
#> [15,] 4.125678 3.784024
#> [16,] 4.269098 3.923570
#> ATCTGCCGTCGTGGCT-300.1.3 ATGAGGGAGCTGCCCA-300.1.3
#> [1,] 4.426707 4.388158
#> [2,] 3.895582 3.586032
#> [3,] 4.010040 3.897267
#> [4,] 4.358936 4.179656
#> [5,] 4.815763 5.308704
#> [6,] 3.993474 3.955972
#> [7,] 4.640060 5.064777
#> [8,] 4.230924 4.207996
#> [9,] 4.061747 4.069332
#> [10,] 3.885040 3.639170
#> [11,] 4.127008 3.849190
#> [12,] 3.995482 3.700911
#> [13,] 4.265562 4.219636
#> [14,] 3.962349 4.269231
#> [15,] 4.117470 4.001518
#> [16,] 4.427711 4.253036
#> ATGTGTGGTTACGTCA-300.1.3 ATTACTCGTGCTGTAT-300.1.3
#> [1,] 4.619225 4.793642
#> [2,] 3.461498 3.425108
#> [3,] 4.082847 3.855065
#> [4,] 3.880510 4.150862
#> [5,] 4.695167 5.800647
#> [6,] 3.703664 3.747306
#> [7,] 4.894849 5.286638
#> [8,] 4.049920 4.133621
#> [9,] 4.343070 4.019935
#> [10,] 3.631439 3.622845
#> [11,] 3.758895 4.085668
#> [12,] 4.430696 3.809806
#> [13,] 4.206585 4.243534
#> [14,] 4.661179 4.318427
#> [15,] 4.285183 3.978448
#> [16,] 4.029209 4.223060
#> ATTACTCTCTGCTTGC-300.1.3 CAACCTCGTCTGGTCG-300.1.3
#> [1,] 4.330692 4.263261
#> [2,] 4.055476 4.198428
#> [3,] 4.229827 4.084479
#> [4,] 4.042507 4.410609
#> [5,] 4.963977 4.364440
#> [6,] 4.306916 3.942043
#> [7,] 4.898415 4.417485
#> [8,] 4.258646 4.687623
#> [9,] 4.174352 4.386051
#> [10,] 4.056196 4.432220
#> [11,] 3.976225 4.230845
#> [12,] 4.123919 4.191552
#> [13,] 4.235591 4.532417
#> [14,] 4.222622 3.982318
#> [15,] 4.196686 4.052063
#> [16,] 4.468300 4.674853
#> CAAGGCCCAACTGCGC-300.1.3 CACACAATCGTACGGC-300.1.3
#> [1,] 4.273112 4.810538
#> [2,] 4.002117 3.557735
#> [3,] 4.416373 3.881726
#> [4,] 4.367678 4.118834
#> [5,] 5.046577 4.586883
#> [6,] 4.064926 4.210202
#> [7,] 4.598447 4.545404
#> [8,] 4.478476 4.280830
#> [9,] 4.014114 4.102578
#> [10,] 4.148906 3.917601
#> [11,] 3.995060 4.339126
#> [12,] 4.112915 4.269058
#> [13,] 4.285815 4.268498
#> [14,] 4.048694 4.280830
#> [15,] 4.050106 3.855381
#> [16,] 4.361327 3.831839
#> CACACCTGTTCCACGG-300.1.3 CACACTCTCCTTGACC-300.1.3
#> [1,] 4.431818 4.696906
#> [2,] 3.779685 3.749869
#> [3,] 4.009276 3.938647
#> [4,] 3.849722 4.215522
#> [5,] 5.149814 5.140535
#> [6,] 4.001391 3.982695
#> [7,] 5.351577 4.817514
#> [8,] 4.228664 4.304143
#> [9,] 4.051484 3.996329
#> [10,] 3.912338 3.642895
#> [11,] 4.025510 3.904562
#> [12,] 3.934601 3.878343
#> [13,] 4.262987 4.194546
#> [14,] 4.564935 4.116413
#> [15,] 3.547774 4.034085
#> [16,] 3.876160 4.318825
#> CACAGTAGTAGCTGCC-300.1.3 CACAGTAGTCATCCCT-300.1.3
#> [1,] 4.138559 4.544025
#> [2,] 4.311164 3.791105
#> [3,] 4.428345 4.006739
#> [4,] 4.109264 4.272237
#> [5,] 4.629454 4.907907
#> [6,] 4.298496 4.113208
#> [7,] 4.262866 5.021563
#> [8,] 4.885986 4.310872
#> [9,] 4.763262 4.190925
#> [10,] 4.358670 3.622642
#> [11,] 4.315914 4.199461
#> [12,] 4.434679 4.030548
#> [13,] 4.629454 4.286613
#> [14,] 4.165479 4.383648
#> [15,] 4.083135 3.958221
#> [16,] 4.403800 4.182390
#> CACATAGGTGGCGAAT-300.1.3 CACCAGGCACATGTGT-300.1.3
#> [1,] 4.340677 4.654070
#> [2,] 3.805665 3.875000
#> [3,] 3.851298 4.217297
#> [4,] 3.837923 4.376453
#> [5,] 5.343037 4.700581
#> [6,] 4.033832 4.137355
#> [7,] 4.665618 4.354651
#> [8,] 4.114870 4.350291
#> [9,] 4.139260 4.175872
#> [10,] 3.809599 4.232558
#> [11,] 4.326515 4.073401
#> [12,] 4.143194 4.375727
#> [13,] 4.173092 4.127180
#> [14,] 4.500393 4.187500
#> [15,] 3.929976 4.062500
#> [16,] 4.708104 4.136628
#> CACCTTGGTTCTGTTT-300.1.3 CACTCCATCTCGAGTA-300.1.3
#> [1,] 4.540064 4.757636
#> [2,] 3.933494 3.951928
#> [3,] 4.137821 3.800200
#> [4,] 4.112981 4.047071
#> [5,] 4.765224 5.054081
#> [6,] 4.042468 4.054081
#> [7,] 4.665865 4.489234
#> [8,] 4.414263 4.376064
#> [9,] 4.081731 3.981472
#> [10,] 4.004808 3.717076
#> [11,] 4.322115 4.011517
#> [12,] 4.274840 3.821733
#> [13,] 4.160256 4.209815
#> [14,] 4.148237 4.034552
#> [15,] 4.003205 4.123686
#> [16,] 4.259615 4.562344
#> CAGCAGCCATGGTCTA-300.1.3 CAGGTGCTCTCGTATT-300.1.3
#> [1,] 4.531204 4.451889
#> [2,] 3.808354 3.522418
#> [3,] 4.230958 3.986902
#> [4,] 4.492383 4.268010
#> [5,] 4.892383 4.995466
#> [6,] 4.060934 3.872040
#> [7,] 5.121376 4.886650
#> [8,] 4.521376 4.231234
#> [9,] 4.320885 4.348111
#> [10,] 4.225553 3.821662
#> [11,] 4.388206 3.981864
#> [12,] 4.152334 4.126448
#> [13,] 4.101229 4.486650
#> [14,] 4.250123 4.310831
#> [15,] 3.809828 3.946096
#> [16,] 4.088452 4.029723
#> CAGTAACCATCGGTTA-300.1.3 CAGTAACGTACTCTCC-300.1.3
#> [1,] 4.995518 4.671907
#> [2,] 3.566947 3.630895
#> [3,] 4.126611 4.017772
#> [4,] 4.022409 4.254272
#> [5,] 5.066667 5.208476
#> [6,] 4.153501 3.795625
#> [7,] 5.068347 4.869446
#> [8,] 4.345658 4.285714
#> [9,] 4.030252 4.118250
#> [10,] 3.709244 3.751880
#> [11,] 4.253221 4.028708
#> [12,] 4.167507 4.004101
#> [13,] 4.326050 4.155844
#> [14,] 4.086835 4.177033
#> [15,] 4.205602 3.829802
#> [16,] 4.521569 4.004101
#> CATATGGGTTGGTGGA-300.1.3 CATCAAGGTACAGTGG-300.1.3
#> [1,] 4.452966 4.720815
#> [2,] 4.181546 3.740639
#> [3,] 4.295986 3.969163
#> [4,] 3.941282 4.338656
#> [5,] 4.620731 5.198238
#> [6,] 4.153984 3.645925
#> [7,] 4.018574 4.623348
#> [8,] 4.512882 4.546806
#> [9,] 4.191132 4.022026
#> [10,] 4.288796 3.632159
#> [11,] 4.008388 3.982379
#> [12,] 4.216896 4.278084
#> [13,] 4.482325 4.272026
#> [14,] 3.959856 3.987885
#> [15,] 4.321150 4.127753
#> [16,] 4.391851 4.266520
#> CATCAGAAGTATCGAA-300.1.3 CATCGGGGTCCGAAGA-300.1.3
#> [1,] 4.383337 4.293595
#> [2,] 3.652089 3.957514
#> [3,] 3.960420 4.064046
#> [4,] 4.242121 4.163602
#> [5,] 5.422673 4.902346
#> [6,] 4.022477 3.996829
#> [7,] 5.119961 4.875713
#> [8,] 4.141461 4.247305
#> [9,] 3.973613 4.303741
#> [10,] 3.751038 3.978440
#> [11,] 4.045443 4.406468
#> [12,] 3.987784 3.962587
#> [13,] 4.187637 4.280279
#> [14,] 4.279746 4.487635
#> [15,] 3.961398 3.783133
#> [16,] 4.077938 4.237793
#> CATTCGCCAGTACACT-300.1.3 CCACGGACAGGTCCAC-300.1.3
#> [1,] 4.444616 4.400191
#> [2,] 4.216905 3.998087
#> [3,] 4.300270 4.223046
#> [4,] 4.256658 4.202008
#> [5,] 4.311463 4.900789
#> [6,] 4.184485 4.089170
#> [7,] 4.239676 4.790342
#> [8,] 4.779622 4.434377
#> [9,] 4.498263 4.210375
#> [10,] 4.252412 4.021755
#> [11,] 4.199151 4.259861
#> [12,] 4.553454 4.242171
#> [13,] 4.334234 4.282572
#> [14,] 4.178310 4.285202
#> [15,] 4.192204 4.124074
#> [16,] 4.566963 4.225436
#> CCACTACGTAAATGTG-300.1.3 CCATGTCTCAACGGGA-300.1.3
#> [1,] 4.649516 4.689298
#> [2,] 3.834947 3.863744
#> [3,] 3.943963 4.274399
#> [4,] 4.152318 4.220179
#> [5,] 5.139073 4.790193
#> [6,] 4.158940 4.166431
#> [7,] 4.703515 4.535596
#> [8,] 4.305655 4.314474
#> [9,] 4.196128 4.345120
#> [10,] 3.926643 4.002829
#> [11,] 4.201732 4.264498
#> [12,] 3.998981 4.044319
#> [13,] 4.260316 4.130127
#> [14,] 4.207845 4.041018
#> [15,] 4.016302 3.778406
#> [16,] 4.433520 4.096181
#> CCATTCGCAGACACTT-300.1.3 CCATTCGCATGGTCAT-300.1.3
#> [1,] 4.2890 4.845217
#> [2,] 3.4855 3.621390
#> [3,] 3.7270 3.701264
#> [4,] 4.3590 4.311372
#> [5,] 5.1325 5.229693
#> [6,] 3.7555 3.890794
#> [7,] 4.8925 4.781137
#> [8,] 4.1855 4.206227
#> [9,] 4.3380 3.881769
#> [10,] 3.6200 3.634928
#> [11,] 3.8930 4.008123
#> [12,] 4.0365 3.851534
#> [13,] 4.3955 4.278430
#> [14,] 3.9720 4.010830
#> [15,] 3.7095 4.216606
#> [16,] 3.9440 4.421029
#> CCCAATCGTAATCACC-300.1.3 CCCAGTTCAGTATCTG-300.1.3
#> [1,] 4.801709 4.647283
#> [2,] 4.525641 3.589674
#> [3,] 4.116239 3.934239
#> [4,] 4.322222 4.629891
#> [5,] 4.884615 4.819022
#> [6,] 4.242735 3.820109
#> [7,] 3.979487 4.820109
#> [8,] 4.641026 4.333696
#> [9,] 4.755556 3.945652
#> [10,] 3.923077 3.764130
#> [11,] 4.138462 3.832065
#> [12,] 3.932479 3.661957
#> [13,] 4.595726 4.242935
#> [14,] 4.125641 4.026087
#> [15,] 3.825641 3.860870
#> [16,] 4.647863 3.907065
#> CCCATACCATACGCTA-300.1.3 CCGGTAGCATCATCCC-300.1.3
#> [1,] 4.420349 4.599037
#> [2,] 3.898800 4.005418
#> [3,] 4.273050 4.174594
#> [4,] 4.135843 4.276942
#> [5,] 5.135297 4.498495
#> [6,] 3.891708 3.912101
#> [7,] 4.809329 4.291993
#> [8,] 4.319149 4.532210
#> [9,] 4.158211 4.479831
#> [10,] 3.891162 4.143889
#> [11,] 4.141571 3.954846
#> [12,] 4.178669 4.379290
#> [13,] 4.256683 4.448525
#> [14,] 4.310420 4.255870
#> [15,] 4.179487 4.022878
#> [16,] 4.166667 3.954244
#> CCTAGCTGTAAATGTG-300.1.3 CCTTACGAGTACACCT-300.1.3
#> [1,] 4.503268 4.304893
#> [2,] 3.471777 4.176077
#> [3,] 3.978015 4.031786
#> [4,] 4.323232 4.371811
#> [5,] 4.900772 4.808030
#> [6,] 4.009507 3.826014
#> [7,] 5.042781 4.698034
#> [8,] 4.165775 4.400251
#> [9,] 4.114082 4.240903
#> [10,] 4.184195 3.974488
#> [11,] 4.163399 4.366374
#> [12,] 4.069519 4.073191
#> [13,] 4.416518 4.246340
#> [14,] 4.434938 4.398578
#> [15,] 3.821153 3.706399
#> [16,] 3.749257 4.052279
#> CCTTACGTCCCAACGG-300.1.3 CCTTACGTCTCCAACC-300.1.3
#> [1,] 4.329612 4.620269
#> [2,] 4.426901 3.834509
#> [3,] 4.203881 4.132136
#> [4,] 3.995747 4.278384
#> [5,] 4.713450 4.763310
#> [6,] 4.043062 3.931366
#> [7,] 4.022063 4.451572
#> [8,] 4.927166 4.386786
#> [9,] 4.236045 4.198845
#> [10,] 4.105795 3.917255
#> [11,] 4.324296 4.269403
#> [12,] 4.213184 4.113534
#> [13,] 4.196704 4.452854
#> [14,] 4.233652 4.036562
#> [15,] 4.156034 3.880693
#> [16,] 4.190324 4.155869
#> CCTTCGAGTGCAACGA-300.1.3 CGAATGTGTTATCGGT-300.1.3
#> [1,] 4.170199 4.298818
#> [2,] 4.584768 4.239730
#> [3,] 4.062914 4.321891
#> [4,] 4.200662 4.076533
#> [5,] 4.605298 4.367473
#> [6,] 4.262252 4.024198
#> [7,] 4.470199 4.205402
#> [8,] 4.994702 4.710186
#> [9,] 4.190728 4.460889
#> [10,] 4.421192 4.241981
#> [11,] 4.530464 4.238042
#> [12,] 4.130464 4.268430
#> [13,] 4.348344 4.510974
#> [14,] 4.615232 4.125492
#> [15,] 3.886755 4.004502
#> [16,] 4.656291 4.540236
#> CGACTTCCACGCCAGT-300.1.3 CGAGCACTCGGCTTGG-300.1.3
#> [1,] 4.570011 4.527151
#> [2,] 3.690181 3.975645
#> [3,] 3.993619 4.108064
#> [4,] 4.270826 4.237597
#> [5,] 4.835874 4.852787
#> [6,] 3.864942 4.105719
#> [7,] 4.557604 4.482049
#> [8,] 4.430344 4.419809
#> [9,] 4.200638 4.277467
#> [10,] 3.874158 3.969872
#> [11,] 3.854661 3.971315
#> [12,] 3.996455 4.265741
#> [13,] 4.461538 4.296410
#> [14,] 4.159518 4.020566
#> [15,] 3.993974 4.185098
#> [16,] 4.247430 4.154790
#> CGAGCCAGTCAAAGCG-300.1.3 CGATGGCAGTCATCCA-300.1.3
#> [1,] 4.684456 4.356827
#> [2,] 3.549741 3.895311
#> [3,] 3.842487 4.252138
#> [4,] 3.870466 4.194928
#> [5,] 5.514508 5.065467
#> [6,] 4.015026 4.005898
#> [7,] 5.138860 4.697139
#> [8,] 4.262694 4.378060
#> [9,] 3.826425 4.100855
#> [10,] 3.834715 3.891477
#> [11,] 4.049223 4.105279
#> [12,] 3.815026 4.247715
#> [13,] 4.173575 4.219404
#> [14,] 4.518653 4.206429
#> [15,] 4.010363 4.327042
#> [16,] 4.395337 4.441463
#> CGATGTAAGTAGGTGC-300.1.3 CGATGTAAGTGGAGAA-300.1.3
#> [1,] 4.498292 4.570815
#> [2,] 4.017082 4.039342
#> [3,] 4.297218 3.648784
#> [4,] 4.520742 3.979256
#> [5,] 4.856515 5.457797
#> [6,] 4.163494 3.718169
#> [7,] 4.358224 4.527897
#> [8,] 4.673499 4.416309
#> [9,] 4.402635 4.067239
#> [10,] 4.102489 3.615880
#> [11,] 3.962909 4.271817
#> [12,] 4.288921 3.654506
#> [13,] 4.466081 3.874821
#> [14,] 3.908736 4.571531
#> [15,] 4.085408 3.682403
#> [16,] 4.355783 4.199571
#> CGATGTAGTCACTGGC-300.1.3 CGATGTAGTGAGGCTA-300.1.3
#> [1,] 4.802475 4.441073
#> [2,] 3.880198 4.215949
#> [3,] 4.276238 4.377558
#> [4,] 4.307426 3.880734
#> [5,] 5.037624 4.929428
#> [6,] 4.028713 3.848977
#> [7,] 4.239109 4.435427
#> [8,] 4.365842 4.654199
#> [9,] 3.832673 4.133380
#> [10,] 4.045050 3.918137
#> [11,] 3.860396 4.220183
#> [12,] 3.961386 3.941426
#> [13,] 4.034653 4.193366
#> [14,] 3.988119 4.157375
#> [15,] 4.230693 4.118560
#> [16,] 4.445050 4.739591
#> CGATTGAGTTATGTGC-300.1.3 CGCCAAGCAAGCTGTT-300.1.3
#> [1,] 4.096979 4.661989
#> [2,] 4.059618 3.563148
#> [3,] 4.249603 3.886516
#> [4,] 4.229730 4.497865
#> [5,] 5.031797 4.769982
#> [6,] 4.267091 4.014643
#> [7,] 4.602544 4.443563
#> [8,] 4.207472 4.422209
#> [9,] 3.974563 4.364246
#> [10,] 4.206677 3.786455
#> [11,] 4.303657 3.976815
#> [12,] 3.994436 4.006101
#> [13,] 4.093005 4.089689
#> [14,] 4.305246 4.392312
#> [15,] 4.149444 4.018914
#> [16,] 4.158983 3.829774
#> CGCGGTATCAAGGTAA-300.1.3 CGCGTTTAGTGGAGTC-300.1.3
#> [1,] 4.664630 4.442760
#> [2,] 4.096518 3.722948
#> [3,] 4.176542 3.829587
#> [4,] 4.150886 4.591741
#> [5,] 5.014661 5.008887
#> [6,] 4.252291 4.143753
#> [7,] 4.357361 4.949294
#> [8,] 4.517410 4.198641
#> [9,] 3.851558 4.182436
#> [10,] 4.013439 3.952953
#> [11,] 4.197312 4.152640
#> [12,] 3.918143 4.085206
#> [13,] 4.159438 4.313121
#> [14,] 4.304826 4.053319
#> [15,] 4.346976 4.089911
#> [16,] 4.610874 3.785677
#> CGCGTTTCAGCTGTAT-300.1.3 CGGACACGTCACTGGC-300.1.3
#> [1,] 4.100324 4.252785
#> [2,] 4.249838 3.632391
#> [3,] 4.153398 3.589546
#> [4,] 4.252427 4.266495
#> [5,] 4.337217 5.395887
#> [6,] 4.177346 4.144816
#> [7,] 4.113269 5.086547
#> [8,] 4.717152 4.121680
#> [9,] 4.562460 4.206512
#> [10,] 4.265372 4.010283
#> [11,] 4.381230 3.967438
#> [12,] 4.372168 3.804627
#> [13,] 4.524919 4.224507
#> [14,] 4.240129 4.289632
#> [15,] 4.149515 3.661525
#> [16,] 4.790291 4.203942
#> CGGACACGTTTGCATG-300.1.3 CGGACGTTCTGATTCT-300.1.3
#> [1,] 4.684269 4.507812
#> [2,] 3.797110 4.105208
#> [3,] 4.063924 4.240625
#> [4,] 4.727626 4.134375
#> [5,] 4.685381 4.586458
#> [6,] 4.058366 4.204687
#> [7,] 4.623124 4.264062
#> [8,] 4.433574 4.610938
#> [9,] 4.277932 4.353125
#> [10,] 3.873819 4.272396
#> [11,] 4.215120 4.033333
#> [12,] 3.908282 4.636458
#> [13,] 4.310728 4.518229
#> [14,] 4.293496 3.975521
#> [15,] 4.043357 4.116146
#> [16,] 4.239022 4.371875
#> CGGAGCTTCTCAAACG-300.1.3 CGGAGTCCACACCGCA-300.1.3
#> [1,] 4.210342 4.622912
#> [2,] 4.467134 4.473349
#> [3,] 4.684487 4.264121
#> [4,] 4.224365 4.396977
#> [5,] 4.198072 4.253779
#> [6,] 4.510955 4.521082
#> [7,] 4.110429 4.360382
#> [8,] 4.916740 4.539379
#> [9,] 4.906223 4.493238
#> [10,] 4.410167 4.340493
#> [11,] 4.150745 4.226730
#> [12,] 4.347940 4.854415
#> [13,] 4.368975 4.606205
#> [14,] 4.275197 3.985680
#> [15,] 4.337423 4.225935
#> [16,] 4.936897 4.405728
#> CGGTTAAGTATAGGTA-300.1.3 CGTCAGGCAATGGAGC-300.1.3
#> [1,] 4.472222 4.224984
#> [2,] 3.708333 4.466539
#> [3,] 3.923387 4.528999
#> [4,] 4.094534 4.421287
#> [5,] 4.803315 4.714468
#> [6,] 3.783602 4.144678
#> [7,] 4.552867 4.500319
#> [8,] 4.560484 4.629063
#> [9,] 4.315860 4.497769
#> [10,] 3.917563 4.146590
#> [11,] 3.730287 4.441683
#> [12,] 4.372312 4.262588
#> [13,] 4.274642 4.246017
#> [14,] 4.291667 4.369662
#> [15,] 4.155914 4.314850
#> [16,] 4.318996 4.137030
#> CGTCAGGGTCAGAATA-300.1.3 CGTCCATCACAGGTTT-300.1.3
#> [1,] 4.810345 4.814973
#> [2,] 3.434372 3.745587
#> [3,] 3.802558 3.918442
#> [4,] 3.873192 4.240414
#> [5,] 5.249166 4.622033
#> [6,] 3.805339 4.264760
#> [7,] 5.014461 4.527085
#> [8,] 3.998888 4.419355
#> [9,] 4.131257 4.151552
#> [10,] 3.434372 3.907486
#> [11,] 4.272525 4.395618
#> [12,] 4.075640 4.270846
#> [13,] 4.155172 4.270237
#> [14,] 4.516129 4.286671
#> [15,] 3.654060 3.906878
#> [16,] 4.201891 4.216677
#> CGTCCATCAGTAACGG-300.1.3 CGTCTACGTGACCAAG-300.1.3
#> [1,] 4.429224 4.671429
#> [2,] 3.344178 3.946356
#> [3,] 3.835616 4.159767
#> [4,] 4.086758 4.321283
#> [5,] 5.184932 5.129155
#> [6,] 3.952055 3.995335
#> [7,] 4.995434 4.420991
#> [8,] 4.244292 4.226239
#> [9,] 4.207192 3.902915
#> [10,] 3.872717 4.003207
#> [11,] 4.212329 4.079883
#> [12,] 3.910959 4.137318
#> [13,] 4.250571 4.152478
#> [14,] 4.489155 4.213703
#> [15,] 3.686073 4.193586
#> [16,] 3.885274 4.441108
#> CGTCTACTCAGCATGT-300.1.3 CGTGAGCCACGCGAAA-300.1.3
#> [1,] 4.248207 4.404215
#> [2,] 3.604781 4.565134
#> [3,] 3.798406 4.750319
#> [4,] 4.041036 4.517241
#> [5,] 5.231474 4.328863
#> [6,] 3.902390 3.967433
#> [7,] 4.998805 4.487229
#> [8,] 4.037450 4.778416
#> [9,] 3.932669 4.377395
#> [10,] 3.725896 4.160920
#> [11,] 3.901195 4.226054
#> [12,] 3.982470 4.337803
#> [13,] 4.219124 4.057471
#> [14,] 4.129482 4.141762
#> [15,] 3.728685 4.270754
#> [16,] 3.983267 4.283525
#> CGTGAGCTCCTTAATC-300.1.3 CGTGTCTCAAAGCGGT-300.1.3
#> [1,] 4.342965 4.664317
#> [2,] 3.896801 3.762996
#> [3,] 4.244582 4.002643
#> [4,] 4.205366 4.133040
#> [5,] 4.903337 5.065198
#> [6,] 3.920193 4.000000
#> [7,] 4.677331 5.074890
#> [8,] 4.370485 4.193833
#> [9,] 3.983144 4.066960
#> [10,] 4.083935 3.854626
#> [11,] 4.031992 4.239648
#> [12,] 4.200550 3.838767
#> [13,] 4.160303 4.306608
#> [14,] 4.186447 4.534802
#> [15,] 4.308566 4.195595
#> [16,] 4.044720 4.400000
#> CGTTCTGAGTGCCATT-300.1.3 CGTTGGGAGCTGCCCA-300.1.3
#> [1,] 4.279341 4.477157
#> [2,] 3.904790 3.648731
#> [3,] 4.079940 3.730457
#> [4,] 4.225299 4.390863
#> [5,] 5.146108 4.995431
#> [6,] 3.957934 3.851777
#> [7,] 4.988024 5.214721
#> [8,] 4.210479 4.171066
#> [9,] 4.222605 3.930457
#> [10,] 3.956138 3.780711
#> [11,] 4.103743 4.156853
#> [12,] 4.101198 3.781218
#> [13,] 4.239521 4.239594
#> [14,] 4.418114 4.243655
#> [15,] 3.786078 3.817259
#> [16,] 4.015569 4.050761
#> CTAACTTAGCTTTGGT-300.1.3 CTAACTTAGGCGTACA-300.1.3
#> [1,] 4.306816 4.282365
#> [2,] 4.122905 4.090214
#> [3,] 4.183240 4.397554
#> [4,] 4.193296 4.201835
#> [5,] 5.022570 4.648318
#> [6,] 4.181006 4.641182
#> [7,] 4.912626 4.269113
#> [8,] 4.372514 4.721203
#> [9,] 4.221229 4.718654
#> [10,] 4.088939 4.441386
#> [11,] 4.247151 4.596330
#> [12,] 4.147709 4.198777
#> [13,] 4.347039 4.101937
#> [14,] 4.339441 4.548930
#> [15,] 3.962905 4.195719
#> [16,] 4.238659 4.399592
#> CTAAGACAGCTGAACG-300.1.3 CTAAGACCAAGGACAC-300.1.3
#> [1,] 4.837786 4.057026
#> [2,] 4.145038 4.113035
#> [3,] 4.078244 4.430754
#> [4,] 4.524809 4.241344
#> [5,] 4.840649 4.532587
#> [6,] 4.283397 4.562118
#> [7,] 4.275763 4.423625
#> [8,] 4.087786 4.623218
#> [9,] 4.302481 4.253564
#> [10,] 3.842557 4.409369
#> [11,] 3.991412 4.409369
#> [12,] 3.999046 4.263747
#> [13,] 4.238550 4.351324
#> [14,] 3.923664 4.073320
#> [15,] 4.090649 4.151731
#> [16,] 4.617366 4.741344
#> CTAGCCTCATGCCTAA-300.1.3 CTAGCCTGTGGTCTCG-300.1.3
#> [1,] 4.297786 4.292630
#> [2,] 3.801573 4.229769
#> [3,] 4.119755 4.373555
#> [4,] 4.079254 4.268786
#> [5,] 5.155012 4.463873
#> [6,] 4.076340 4.223266
#> [7,] 5.058275 4.445809
#> [8,] 4.137529 4.374277
#> [9,] 4.111014 4.483382
#> [10,] 4.004953 4.199422
#> [11,] 4.188811 4.075145
#> [12,] 4.047786 4.314306
#> [13,] 4.312937 4.056358
#> [14,] 4.434441 4.415462
#> [15,] 3.900350 4.193642
#> [16,] 4.034674 4.294798
#> CTAGCCTTCACCGGGT-300.1.3 CTAGCCTTCTATGTGG-300.1.3
#> [1,] 4.689739 4.239044
#> [2,] 4.336976 4.314741
#> [3,] 4.228294 4.319721
#> [4,] 4.054645 4.314741
#> [5,] 4.420765 4.328685
#> [6,] 3.931390 4.306773
#> [7,] 4.405586 4.193227
#> [8,] 4.489375 4.843625
#> [9,] 4.422587 4.337649
#> [10,] 4.256831 4.511952
#> [11,] 3.976928 4.395418
#> [12,] 4.595628 4.456175
#> [13,] 4.418944 4.544821
#> [14,] 4.023072 4.107570
#> [15,] 3.930176 3.929283
#> [16,] 4.360049 4.570717
#> CTCAGAATCGGATGTT-300.1.3 CTCATTAAGCAGCGTA-300.1.3
#> [1,] 4.512215 4.596864
#> [2,] 4.200326 3.712190
#> [3,] 4.603420 3.988872
#> [4,] 4.218241 4.412241
#> [5,] 4.618078 5.206373
#> [6,] 4.125407 4.053111
#> [7,] 4.418567 4.682853
#> [8,] 4.501629 4.257967
#> [9,] 4.164495 3.654527
#> [10,] 4.175081 3.768336
#> [11,] 4.375407 3.974709
#> [12,] 4.128664 3.893273
#> [13,] 4.230456 4.107233
#> [14,] 3.894137 4.181082
#> [15,] 4.171010 4.298938
#> [16,] 4.394951 4.203844
#> CTCGTACTCATGTCTT-300.1.3 CTCGTCATCTTGAGAC-300.1.3
#> [1,] 4.709869 4.753375
#> [2,] 3.730678 3.799065
#> [3,] 3.974435 4.386293
#> [4,] 4.070749 4.346314
#> [5,] 5.011296 5.111630
#> [6,] 3.846611 3.869159
#> [7,] 5.236029 4.870197
#> [8,] 4.306778 4.281931
#> [9,] 4.228894 4.109553
#> [10,] 3.929845 3.952233
#> [11,] 4.161118 4.120457
#> [12,] 4.132580 4.086708
#> [13,] 4.240785 4.259086
#> [14,] 4.196790 4.379543
#> [15,] 3.847206 3.750779
#> [16,] 4.390012 3.930945
#> CTCTGGTTCTACGAGT-300.1.3 CTGAAACGTCGCGGTT-300.1.3
#> [1,] 4.651019 4.738392
#> [2,] 3.843054 3.778596
#> [3,] 3.975818 4.123443
#> [4,] 4.450925 4.338618
#> [5,] 4.806543 4.585504
#> [6,] 4.169275 3.896376
#> [7,] 4.496444 4.784258
#> [8,] 4.480797 4.335221
#> [9,] 4.106686 3.927520
#> [10,] 3.996681 4.092865
#> [11,] 3.795638 3.821065
#> [12,] 4.234234 4.056059
#> [13,] 4.286392 4.437146
#> [14,] 3.998103 3.986410
#> [15,] 4.248459 3.822763
#> [16,] 4.004267 4.250849
#> CTGATAGGTGAGGGAG-300.1.3 CTGCCTAAGCTGCCCA-300.1.3
#> [1,] 4.409344 4.378995
#> [2,] 3.995829 3.777778
#> [3,] 4.280868 3.537291
#> [4,] 4.396552 4.265601
#> [5,] 5.258899 5.259513
#> [6,] 4.119021 3.538052
#> [7,] 4.879310 4.697869
#> [8,] 4.114572 4.475647
#> [9,] 4.131257 4.017504
#> [10,] 4.052836 3.643075
#> [11,] 3.959677 3.950533
#> [12,] 4.172692 3.761035
#> [13,] 4.487208 4.137747
#> [14,] 4.361235 4.616438
#> [15,] 3.743882 3.733638
#> [16,] 3.887653 3.733638
#> CTGCCTATCATTGCGA-300.1.3 CTGTGCTCACAGATTC-300.1.3
#> [1,] 4.295705 4.440873
#> [2,] 3.724898 3.884475
#> [3,] 4.280325 4.048514
#> [4,] 4.195589 4.476653
#> [5,] 4.736216 5.102486
#> [6,] 4.054556 4.068830
#> [7,] 4.676436 4.873560
#> [8,] 4.264074 4.346877
#> [9,] 4.383633 4.227411
#> [10,] 3.909460 4.101577
#> [11,] 3.946895 4.247726
#> [12,] 4.141033 3.980898
#> [13,] 4.329077 4.296240
#> [14,] 4.355485 4.221649
#> [15,] 4.072548 4.129169
#> [16,] 4.216773 4.178290
#> CTGTTTATCATGCAAC-300.1.3 CTGTTTATCTAACCGA-300.1.3
#> [1,] 4.362919 4.434638
#> [2,] 3.997041 4.136553
#> [3,] 4.380671 4.343880
#> [4,] 4.168639 3.981682
#> [5,] 4.533531 4.669442
#> [6,] 3.884615 3.976686
#> [7,] 4.343195 4.466278
#> [8,] 4.374753 4.422981
#> [9,] 4.060158 4.302248
#> [10,] 3.932939 4.082431
#> [11,] 4.098619 4.128226
#> [12,] 4.340237 4.327227
#> [13,] 3.844181 4.398002
#> [14,] 4.034517 4.287261
#> [15,] 4.321499 4.158201
#> [16,] 4.138067 4.118235
#> CTTAACTCATGGGAAC-300.1.3 CTTACCGGTCATCCCT-300.1.3
#> [1,] 4.7480 4.491633
#> [2,] 3.7830 4.162724
#> [3,] 4.0615 4.007501
#> [4,] 4.4360 4.287363
#> [5,] 5.0350 4.706867
#> [6,] 3.9525 3.961339
#> [7,] 4.9310 4.605886
#> [8,] 4.2885 4.572418
#> [9,] 4.1665 4.143104
#> [10,] 3.8690 3.956145
#> [11,] 4.0155 3.870167
#> [12,] 3.9250 3.929602
#> [13,] 4.1245 4.574726
#> [14,] 4.1170 4.081939
#> [15,] 3.8115 3.975188
#> [16,] 3.9855 4.342758
#> CTTCTCTGTCCAACTA-300.1.3 CTTGGCTAGCCCAATT-300.1.3
#> [1,] 4.510501 4.510267
#> [2,] 3.768444 4.416838
#> [3,] 4.199246 4.061602
#> [4,] 4.036618 4.157084
#> [5,] 5.095315 4.396304
#> [6,] 3.909532 4.239220
#> [7,] 4.944534 4.168378
#> [8,] 3.918686 4.474333
#> [9,] 4.150781 4.733060
#> [10,] 3.901454 4.343943
#> [11,] 4.270328 4.092402
#> [12,] 4.250404 4.314168
#> [13,] 4.278945 4.267967
#> [14,] 4.444803 3.941478
#> [15,] 3.770059 4.231006
#> [16,] 3.963920 4.456879
#> GAACATCTCAGAGCTT-300.1.3 GAACCTACAAGGGTCA-300.1.3
#> [1,] 4.437539 4.245614
#> [2,] 3.619640 4.414230
#> [3,] 3.861405 4.101365
#> [4,] 4.487881 4.085770
#> [5,] 4.670603 4.431774
#> [6,] 3.954009 3.982456
#> [7,] 4.975140 4.040936
#> [8,] 4.174021 4.960039
#> [9,] 3.936607 4.569201
#> [10,] 3.806091 4.242690
#> [11,] 4.126165 4.262183
#> [12,] 3.844002 4.350877
#> [13,] 4.379117 4.724172
#> [14,] 4.383468 4.235867
#> [15,] 3.706650 3.928850
#> [16,] 3.922933 4.755361
#> GAACGGATCACCTTAT-300.1.3 GACCAATCATTGGTAC-300.1.3
#> [1,] 4.329138 4.221549
#> [2,] 4.309777 3.878865
#> [3,] 4.302033 3.846669
#> [4,] 4.286544 4.074275
#> [5,] 4.405615 5.408671
#> [6,] 3.984511 4.023908
#> [7,] 4.114230 5.260121
#> [8,] 4.363988 4.269684
#> [9,] 4.337851 4.034747
#> [10,] 4.431752 3.885878
#> [11,] 4.470474 3.966847
#> [12,] 4.297193 3.844756
#> [13,] 4.550823 4.236850
#> [14,] 4.106486 4.228881
#> [15,] 4.055179 3.775263
#> [16,] 4.514037 3.985974
#> GACCTGGAGTATGACA-300.1.3 GACCTGGGTTATCGGT-300.1.3
#> [1,] 4.340996 4.312139
#> [2,] 3.685276 4.493256
#> [3,] 3.966338 4.414258
#> [4,] 3.882047 4.305074
#> [5,] 5.359606 4.470777
#> [6,] 3.821292 4.497752
#> [7,] 5.384510 4.149647
#> [8,] 3.904488 4.836866
#> [9,] 4.104817 5.074502
#> [10,] 3.710728 4.225434
#> [11,] 4.154351 4.207450
#> [12,] 4.195402 4.557482
#> [13,] 4.380952 4.188182
#> [14,] 4.443076 4.297367
#> [15,] 3.643952 4.161850
#> [16,] 3.742200 4.799615
#> GACGTTAAGATGAGAG-300.1.3 GACTAACAGCGCTCCA-300.1.3
#> [1,] 4.684033 4.183258
#> [2,] 3.794501 3.748303
#> [3,] 4.113362 3.947964
#> [4,] 4.319344 4.263575
#> [5,] 4.666184 5.346154
#> [6,] 4.114809 3.972285
#> [7,] 4.566811 5.328054
#> [8,] 4.435118 4.175339
#> [9,] 4.187168 4.043552
#> [10,] 3.925229 4.140271
#> [11,] 3.919440 4.204751
#> [12,] 4.261939 4.062783
#> [13,] 4.475157 4.206448
#> [14,] 4.534009 4.207579
#> [15,] 3.941148 3.716063
#> [16,] 4.065123 4.245475
#> GACTAACTCTACTCAT-300.1.3 GAGCAGACATCACAAC-300.1.3
#> [1,] 4.231252 4.487617
#> [2,] 3.846601 4.013759
#> [3,] 3.899917 4.194001
#> [4,] 4.160133 4.210787
#> [5,] 5.361683 5.017887
#> [6,] 3.898349 3.960374
#> [7,] 5.190573 4.791139
#> [8,] 4.261692 4.285636
#> [9,] 4.065400 3.938360
#> [10,] 3.894106 4.103742
#> [11,] 4.062448 4.231701
#> [12,] 3.969837 4.176114
#> [13,] 4.298220 4.262521
#> [14,] 4.471728 4.163731
#> [15,] 3.873628 4.220143
#> [16,] 3.996772 4.306824
#> GAGGTGAGTGTGAAAT-300.1.3 GATCAGTCACGACGAA-300.1.3
#> [1,] 4.496264 4.646817
#> [2,] 4.304172 3.626797
#> [3,] 4.129203 4.205339
#> [4,] 4.210772 4.417864
#> [5,] 4.750311 4.729979
#> [6,] 4.215442 3.886037
#> [7,] 4.291407 4.762834
#> [8,] 4.706413 4.352669
#> [9,] 4.286426 4.267967
#> [10,] 4.256227 3.850103
#> [11,] 4.153798 4.459446
#> [12,] 4.284558 4.302875
#> [13,] 4.331569 4.341889
#> [14,] 4.067248 4.281828
#> [15,] 4.072540 3.790041
#> [16,] 4.279577 3.951232
#> GATCGCGAGGGAACGG-300.1.3 GCATGATAGCGTAATA-300.1.3
#> [1,] 4.644885 4.465068
#> [2,] 3.635779 3.969863
#> [3,] 4.019282 4.016438
#> [4,] 4.688806 4.058904
#> [5,] 5.047670 5.409589
#> [6,] 3.947509 3.966438
#> [7,] 4.792180 4.927397
#> [8,] 4.235672 4.423288
#> [9,] 4.108731 4.319863
#> [10,] 3.794322 3.813699
#> [11,] 3.839314 4.214384
#> [12,] 3.904124 3.817808
#> [13,] 4.170327 4.269178
#> [14,] 4.267809 4.358219
#> [15,] 3.983931 4.000685
#> [16,] 3.801285 4.778082
#> GCATGCGGTCTCCCTA-300.1.3 GCATGCGTCTTGCATT-300.1.3
#> [1,] 4.854167 4.705951
#> [2,] 3.904762 3.663944
#> [3,] 3.876488 3.920070
#> [4,] 4.118304 4.015753
#> [5,] 5.014137 5.225204
#> [6,] 3.834821 4.121937
#> [7,] 4.295387 5.017503
#> [8,] 4.268601 4.477830
#> [9,] 4.165923 3.957410
#> [10,] 3.656994 3.904901
#> [11,] 4.104911 4.210035
#> [12,] 3.839286 3.738040
#> [13,] 4.393601 4.074096
#> [14,] 3.932292 4.312719
#> [15,] 3.967262 4.417736
#> [16,] 4.877232 4.512252
#> GCCTCTAAGGACAGCT-300.1.3 GCGACCACATCTCCCA-300.1.3
#> [1,] 4.460847 4.660103
#> [2,] 3.943517 3.727312
#> [3,] 3.800171 4.040240
#> [4,] 4.187420 4.205908
#> [5,] 4.889602 5.166524
#> [6,] 3.988447 3.953767
#> [7,] 4.644844 4.773545
#> [8,] 4.416346 4.200342
#> [9,] 4.424904 4.109589
#> [10,] 3.845956 4.186644
#> [11,] 4.088575 4.159675
#> [12,] 4.140351 4.179366
#> [13,] 4.319641 4.327055
#> [14,] 4.014976 4.207620
#> [15,] 4.077450 3.914384
#> [16,] 4.243047 3.907534
#> GCGACCATCGTGGGAA-300.1.3 GCGCGATGTGATGCCC-300.1.3
#> [1,] 4.632228 4.316399
#> [2,] 4.010794 3.984684
#> [3,] 3.969931 4.217034
#> [4,] 3.962221 4.193874
#> [5,] 5.000771 5.205080
#> [6,] 3.933693 3.971610
#> [7,] 4.158828 4.789690
#> [8,] 4.410948 4.313784
#> [9,] 4.187355 4.150915
#> [10,] 4.009252 3.782592
#> [11,] 3.850424 4.035487
#> [12,] 4.027756 4.264102
#> [13,] 4.422513 4.347777
#> [14,] 4.071704 4.236832
#> [15,] 4.085582 4.095256
#> [16,] 4.875867 4.248412
#> GCTGGGTCATCCGTGG-300.1.3 GCTTCCAAGCTCCCAG-300.1.3
#> [1,] 4.468577 4.551584
#> [2,] 3.811459 3.820929
#> [3,] 4.156784 3.889094
#> [4,] 4.236509 4.137804
#> [5,] 4.942705 4.905306
#> [6,] 3.952476 4.091378
#> [7,] 4.804575 4.744657
#> [8,] 4.398845 4.365512
#> [9,] 4.296469 4.194178
#> [10,] 4.027315 3.965733
#> [11,] 4.193649 3.921518
#> [12,] 4.328226 4.351879
#> [13,] 4.257828 4.327192
#> [14,] 4.236509 4.140383
#> [15,] 4.089052 4.179808
#> [16,] 4.248057 4.162491
#> GGAAAGCAGGCTCAGA-300.1.3 GGAAAGCTCTTCGGTC-300.1.3
#> [1,] 4.438307 4.202174
#> [2,] 3.553949 3.898551
#> [3,] 3.949406 4.254348
#> [4,] 4.300465 4.234058
#> [5,] 5.007228 5.131159
#> [6,] 3.679917 3.889130
#> [7,] 4.996386 4.781884
#> [8,] 4.018585 4.084058
#> [9,] 4.434177 3.959420
#> [10,] 3.936500 3.889855
#> [11,] 3.876613 4.300000
#> [12,] 4.335570 3.937681
#> [13,] 4.397006 4.359420
#> [14,] 4.212700 4.021014
#> [15,] 3.895199 3.864493
#> [16,] 3.979866 4.326812
#> GGAACTTTCGTCTGAA-300.1.3 GGAATAATCCAAATGC-300.1.3
#> [1,] 4.469495 4.646518
#> [2,] 3.778425 3.763469
#> [3,] 4.030782 4.280333
#> [4,] 4.311703 4.340780
#> [5,] 4.989739 5.149365
#> [6,] 4.042429 3.991678
#> [7,] 4.913200 4.910206
#> [8,] 4.169994 4.246167
#> [9,] 4.060177 4.158125
#> [10,] 3.877427 4.190539
#> [11,] 4.218802 4.245729
#> [12,] 4.123960 4.218134
#> [13,] 4.185247 4.091108
#> [14,] 4.287854 4.031537
#> [15,] 4.041043 3.883487
#> [16,] 3.943982 3.999562
#> GGAGCAAGTTTAGCTG-300.1.3 GGCAATTAGGCCCTCA-300.1.3
#> [1,] 4.634745 4.353247
#> [2,] 3.842848 4.129870
#> [3,] 3.985267 4.169697
#> [4,] 4.645181 4.234632
#> [5,] 5.062615 4.428571
#> [6,] 3.843462 4.244156
#> [7,] 4.834254 4.425108
#> [8,] 4.240638 4.859740
#> [9,] 4.150399 4.469264
#> [10,] 3.911602 4.274459
#> [11,] 4.184162 4.290909
#> [12,] 3.978514 4.623377
#> [13,] 4.178023 4.058009
#> [14,] 4.327195 4.128139
#> [15,] 3.896255 4.017316
#> [16,] 3.948435 4.206061
#> GGCAATTGTAATCGTC-300.1.3 GGCGACTTCTCGCATC-300.1.3
#> [1,] 4.779989 4.775437
#> [2,] 3.984522 3.536485
#> [3,] 4.311774 3.918808
#> [4,] 4.369265 4.227133
#> [5,] 4.767828 5.446043
#> [6,] 3.926479 3.815519
#> [7,] 4.788834 4.881295
#> [8,] 4.019900 4.359712
#> [9,] 4.284688 3.855087
#> [10,] 3.920951 3.759507
#> [11,] 3.790492 4.196300
#> [12,] 4.080708 3.764645
#> [13,] 4.337756 4.175231
#> [14,] 4.464345 4.169579
#> [15,] 4.023770 4.461459
#> [16,] 3.860144 4.533402
#> GGCTCGATCGCAAGCC-300.1.3 GGGAATGAGTGTACCT-300.1.3
#> [1,] 4.398247 4.291849
#> [2,] 4.293087 4.204207
#> [3,] 4.135346 4.325153
#> [4,] 3.889971 4.063103
#> [5,] 4.434275 5.147239
#> [6,] 4.200584 4.155127
#> [7,] 4.053554 4.787905
#> [8,] 4.653359 4.375986
#> [9,] 4.196689 4.152498
#> [10,] 4.355404 4.250657
#> [11,] 4.202532 4.303243
#> [12,] 4.215190 4.386503
#> [13,] 4.408958 4.019281
#> [14,] 4.101266 4.432077
#> [15,] 4.333009 4.311131
#> [16,] 4.484907 4.096407
#> GGGAGATAGGCCATAG-300.1.3 GGGAGATAGTGAAGAG-300.1.3
#> [1,] 4.788265 4.219901
#> [2,] 3.964286 3.917472
#> [3,] 4.174490 4.101071
#> [4,] 4.197449 4.150692
#> [5,] 4.922449 5.042048
#> [6,] 3.973980 4.004440
#> [7,] 4.302551 4.767302
#> [8,] 4.266327 4.458605
#> [9,] 4.030102 4.219378
#> [10,] 3.927551 4.063724
#> [11,] 4.245408 4.289632
#> [12,] 4.080612 4.053278
#> [13,] 4.220918 4.128232
#> [14,] 4.230612 4.268739
#> [15,] 4.337755 4.050666
#> [16,] 4.580102 4.436406
#> GGGCACTGTTGTCGCG-300.1.3 GGGTCTGAGCCGATTT-300.1.3
#> [1,] 4.270111 4.442921
#> [2,] 4.410072 4.063785
#> [3,] 4.039241 4.127273
#> [4,] 4.230216 4.221759
#> [5,] 4.524526 5.149627
#> [6,] 4.307390 4.124590
#> [7,] 4.387835 4.958867
#> [8,] 4.810988 4.269151
#> [9,] 4.467626 4.211923
#> [10,] 4.358404 3.883159
#> [11,] 4.226946 4.111475
#> [12,] 4.315893 3.784501
#> [13,] 4.672989 4.128763
#> [14,] 4.330281 4.496274
#> [15,] 4.159581 3.851565
#> [16,] 4.281884 4.116244
#> GGGTTGCTCAGGTAAA-300.1.3 GGGTTGCTCATGTAGC-300.1.3
#> [1,] 4.325995 4.428471
#> [2,] 3.943994 3.882889
#> [3,] 3.780610 4.196353
#> [4,] 4.216686 4.039271
#> [5,] 5.357667 5.239832
#> [6,] 3.974894 3.979663
#> [7,] 5.117034 4.748247
#> [8,] 4.390112 4.287518
#> [9,] 4.000000 4.066620
#> [10,] 3.964465 3.828892
#> [11,] 4.062572 4.338008
#> [12,] 3.727694 4.223703
#> [13,] 4.198532 4.072230
#> [14,] 4.407107 4.273492
#> [15,] 3.913866 3.868163
#> [16,] 3.883739 4.403927
#> GTAACTGCAATGGACG-300.1.3 GTACTTTCAAGTAGTA-300.1.3
#> [1,] 4.671634 4.752960
#> [2,] 3.879139 3.666308
#> [3,] 4.014349 4.102799
#> [4,] 4.370861 4.304090
#> [5,] 5.249448 5.149085
#> [6,] 3.880795 3.784177
#> [7,] 4.819536 5.107643
#> [8,] 4.371965 4.305705
#> [9,] 3.761038 4.010764
#> [10,] 3.798565 3.881593
#> [11,] 3.870861 3.988159
#> [12,] 3.837748 3.955328
#> [13,] 4.272627 4.082347
#> [14,] 4.084989 4.283100
#> [15,] 4.176049 3.645318
#> [16,] 4.142936 3.933800
#> GTCACGGCAATGAAAC-300.1.3 GTCATTTGTACAAGTA-300.1.3
#> [1,] 4.704160 4.651836
#> [2,] 3.711351 3.938661
#> [3,] 3.841808 4.150324
#> [4,] 4.128403 4.121382
#> [5,] 5.205958 4.972786
#> [6,] 3.868516 4.078186
#> [7,] 4.759630 4.395248
#> [8,] 4.326656 4.398704
#> [9,] 3.775039 4.080346
#> [10,] 3.684129 4.059179
#> [11,] 3.983564 4.074730
#> [12,] 3.926040 4.130886
#> [13,] 4.335388 4.213823
#> [14,] 4.297894 4.284233
#> [15,] 4.243965 4.178402
#> [16,] 4.137648 4.489849
#> GTGCAGCCAGGAACGT-300.1.3 GTGCAGCTCTATCCCG-300.1.3
#> [1,] 4.734940 4.276854
#> [2,] 4.324374 4.278133
#> [3,] 4.252085 4.422634
#> [4,] 4.219648 4.216113
#> [5,] 4.480074 4.872762
#> [6,] 4.075070 4.001279
#> [7,] 4.255792 4.394501
#> [8,] 4.588508 4.659847
#> [9,] 4.946247 4.081202
#> [10,] 4.323448 4.124680
#> [11,] 4.252085 4.271100
#> [12,] 4.650602 3.843990
#> [13,] 4.570899 4.270460
#> [14,] 4.594069 4.153453
#> [15,] 3.973123 4.292839
#> [16,] 4.601483 4.533248
#> GTGCGGTTCTTAGCCC-300.1.3 GTGGGTCTCATGCAAC-300.1.3
#> [1,] 4.238856 4.642591
#> [2,] 4.349967 3.871929
#> [3,] 4.592149 3.915860
#> [4,] 4.445775 4.291139
#> [5,] 4.321357 5.019360
#> [6,] 4.114438 3.769918
#> [7,] 4.218230 4.606850
#> [8,] 4.395210 4.436337
#> [9,] 4.379242 4.272524
#> [10,] 4.083167 3.912882
#> [11,] 4.542914 3.895011
#> [12,] 4.446440 4.052867
#> [13,] 4.133733 4.751303
#> [14,] 4.024617 3.931497
#> [15,] 4.262808 3.973939
#> [16,] 4.652029 4.096798
#> GTTAAGCAGGTGCACA-300.1.3 GTTACAGTCTGATTCT-300.1.3
#> [1,] 4.609868 4.846524
#> [2,] 3.617900 3.693048
#> [3,] 4.025818 3.851337
#> [4,] 4.186460 4.013369
#> [5,] 5.083190 5.097326
#> [6,] 4.071142 4.030481
#> [7,] 4.716581 4.525668
#> [8,] 4.318990 4.119786
#> [9,] 4.236948 4.051872
#> [10,] 3.850258 3.690909
#> [11,] 4.220310 3.915508
#> [12,] 3.953528 3.889840
#> [13,] 4.226047 4.103209
#> [14,] 4.099254 4.487166
#> [15,] 3.988526 4.093048
#> [16,] 3.873781 4.382888
#> GTTCGGGTCATGGTCA-300.1.3 GTTCTCGCAACAACCT-300.1.3
#> [1,] 4.441059 4.485714
#> [2,] 4.109864 4.000752
#> [3,] 4.027265 4.220301
#> [4,] 4.028067 4.307519
#> [5,] 4.617482 4.630827
#> [6,] 4.058540 4.066165
#> [7,] 4.370489 4.615038
#> [8,] 4.627907 4.357895
#> [9,] 4.269447 4.155639
#> [10,] 4.237370 3.993985
#> [11,] 3.960706 3.682707
#> [12,] 4.117883 3.919549
#> [13,] 4.448276 4.540602
#> [14,] 4.055333 4.033835
#> [15,] 4.254210 4.074436
#> [16,] 4.178829 4.375188
#> GTTCTCGCAATCCGAT-300.1.3 GTTTCTACAACAACCT-300.1.3
#> [1,] 4.268608 4.311749
#> [2,] 4.016828 3.906527
#> [3,] 4.131392 3.990078
#> [4,] 4.322977 3.993734
#> [5,] 5.254369 5.308094
#> [6,] 4.112621 3.822454
#> [7,] 4.985113 4.767624
#> [8,] 4.165696 4.313838
#> [9,] 4.168285 4.120627
#> [10,] 4.005178 3.951436
#> [11,] 4.132039 4.133159
#> [12,] 4.211003 3.929504
#> [13,] 4.473786 4.110183
#> [14,] 4.443366 4.528982
#> [15,] 3.996764 3.859008
#> [16,] 4.155340 4.420888
#> TAAGAGACATGTTCCC-300.1.3 TACAGTGCAATTCCTT-300.1.3
#> [1,] 4.723776 4.352083
#> [2,] 3.479720 4.289583
#> [3,] 4.107692 4.213542
#> [4,] 4.276923 4.081250
#> [5,] 4.781818 4.764583
#> [6,] 4.050350 4.010417
#> [7,] 4.786713 4.230208
#> [8,] 4.400699 4.782292
#> [9,] 4.168531 4.328125
#> [10,] 3.732168 4.454167
#> [11,] 4.369231 4.228125
#> [12,] 4.141259 4.360417
#> [13,] 4.465035 4.437500
#> [14,] 4.207692 4.323958
#> [15,] 3.813287 4.463542
#> [16,] 3.930769 4.581250
#> TACAGTGTCTGAAAGA-300.1.3 TACCTATTCCATGAGT-300.1.3
#> [1,] 4.996107 4.617647
#> [2,] 3.531146 4.011964
#> [3,] 4.022247 4.376869
#> [4,] 4.426585 4.208375
#> [5,] 4.750834 4.700897
#> [6,] 3.942158 4.247757
#> [7,] 4.573415 4.346461
#> [8,] 4.368187 4.591725
#> [9,] 4.117909 4.495015
#> [10,] 3.820912 4.220837
#> [11,] 4.293660 4.369392
#> [12,] 4.161846 4.361914
#> [13,] 4.187430 4.411266
#> [14,] 4.062291 3.982552
#> [15,] 3.973304 4.044367
#> [16,] 3.864850 4.342971
#> TACCTTAAGACTTGAA-300.1.3 TACCTTAAGGCTAGAC-300.1.3
#> [1,] 4.645867 4.234780
#> [2,] 3.722042 3.983089
#> [3,] 4.190032 4.027903
#> [4,] 4.392220 4.202931
#> [5,] 4.803485 5.193912
#> [6,] 3.978930 3.820462
#> [7,] 4.600486 4.876832
#> [8,] 4.284441 4.244081
#> [9,] 4.155592 4.163754
#> [10,] 3.817261 4.003946
#> [11,] 3.900729 4.141488
#> [12,] 4.164506 4.090192
#> [13,] 4.224473 4.322435
#> [14,] 4.214749 4.489290
#> [15,] 4.222447 4.076663
#> [16,] 4.461507 4.114431
#> TACCTTAGTCTGCGGT-300.1.3 TACCTTAGTTCGAATC-300.1.3
#> [1,] 4.488062 4.711249
#> [2,] 4.047753 3.888543
#> [3,] 4.385534 4.224469
#> [4,] 3.929775 4.862105
#> [5,] 4.709972 5.018144
#> [6,] 3.894663 3.875583
#> [7,] 4.193118 4.756350
#> [8,] 4.386938 4.367030
#> [9,] 4.297051 4.240021
#> [10,] 4.337079 3.728875
#> [11,] 3.922753 3.969414
#> [12,] 4.145365 4.083981
#> [13,] 4.583567 4.179886
#> [14,] 4.110253 4.096423
#> [15,] 4.111657 3.933126
#> [16,] 4.332865 4.024883
#> TACGGATAGCCAGTTT-300.1.3 TACGGATCATGGATGG-300.1.3
#> [1,] 4.856425 5.030780
#> [2,] 3.648603 3.589835
#> [3,] 3.912291 4.121689
#> [4,] 4.486034 4.382248
#> [5,] 5.214525 4.867573
#> [6,] 4.037989 3.671439
#> [7,] 4.990503 4.181102
#> [8,] 4.281564 4.672870
#> [9,] 3.959218 4.293486
#> [10,] 3.931844 3.523980
#> [11,] 3.897207 3.972083
#> [12,] 3.769274 3.793128
#> [13,] 4.159777 4.387974
#> [14,] 4.379330 4.058697
#> [15,] 3.874302 4.126700
#> [16,] 3.588827 4.464567
#> TACGGTAGTTCAACCA-300.1.3 TACTCGCCATCGGGTC-300.1.3
#> [1,] 4.670498 4.675505
#> [2,] 3.916188 4.165404
#> [3,] 4.125479 4.025253
#> [4,] 4.579023 3.987374
#> [5,] 4.980843 4.669823
#> [6,] 4.085249 4.305556
#> [7,] 4.411398 3.981061
#> [8,] 4.410441 4.452020
#> [9,] 4.255747 4.269571
#> [10,] 3.948755 3.995581
#> [11,] 3.886494 3.782197
#> [12,] 3.878352 4.070076
#> [13,] 4.534004 4.506944
#> [14,] 3.952586 3.960227
#> [15,] 4.046935 4.227273
#> [16,] 4.276341 4.344697
#> TACTCGCTCGCCAGCA-300.1.3 TACTTGTAGGGTCTCC-300.1.3
#> [1,] 4.621142 4.218459
#> [2,] 3.430444 3.671979
#> [3,] 3.995349 3.798805
#> [4,] 4.253277 4.119522
#> [5,] 5.293869 5.401726
#> [6,] 3.997463 3.948871
#> [7,] 5.264271 5.219124
#> [8,] 4.227484 4.169323
#> [9,] 4.108245 3.943559
#> [10,] 3.573362 3.541169
#> [11,] 4.187315 4.077025
#> [12,] 4.031712 3.929615
#> [13,] 4.216068 4.082337
#> [14,] 4.169979 4.407039
#> [15,] 4.024524 3.724436
#> [16,] 4.482030 3.939575
#> TACTTGTGTTGTACAC-300.1.3 TAGACCAGTCCCTACT-300.1.3
#> [1,] 4.360856 4.518055
#> [2,] 3.788991 3.863264
#> [3,] 3.945566 4.201252
#> [4,] 4.262997 4.061146
#> [5,] 4.858104 4.685123
#> [6,] 4.004281 4.036591
#> [7,] 4.990826 4.589793
#> [8,] 4.130887 4.402985
#> [9,] 4.038532 4.164179
#> [10,] 4.107645 4.030332
#> [11,] 4.100917 4.446317
#> [12,] 3.992661 4.337506
#> [13,] 4.353517 4.260953
#> [14,] 4.486850 4.303804
#> [15,] 4.083792 3.910929
#> [16,] 3.873394 4.039961
#> TAGCCGGGTGCTCTTC-300.1.3 TAGTGGTCATCGATTG-300.1.3
#> [1,] 4.527657 4.621523
#> [2,] 3.445770 4.314056
#> [3,] 3.807484 4.382870
#> [4,] 4.586226 4.213763
#> [5,] 4.799892 4.472914
#> [6,] 3.762473 4.192533
#> [7,] 5.111171 4.122987
#> [8,] 4.265184 4.336750
#> [9,] 4.028200 4.335286
#> [10,] 3.831345 3.933382
#> [11,] 3.902928 4.078331
#> [12,] 3.868764 4.245974
#> [13,] 4.278742 4.559297
#> [14,] 4.396963 4.091508
#> [15,] 3.592191 4.237921
#> [16,] 3.920282 4.476574
#> TAGTGGTCATCGGTTA-300.1.3 TAGTGGTTCCCAGGTG-300.1.3
#> [1,] 4.201754 4.820850
#> [2,] 3.623904 3.964575
#> [3,] 4.007675 4.258097
#> [4,] 3.961075 4.231781
#> [5,] 4.974232 4.396761
#> [6,] 3.990680 3.836032
#> [7,] 5.076206 4.183198
#> [8,] 3.975329 4.793522
#> [9,] 3.864583 4.103239
#> [10,] 3.742325 4.122470
#> [11,] 3.841009 4.102227
#> [12,] 3.814145 4.336032
#> [13,] 4.286732 4.431174
#> [14,] 4.205592 4.059717
#> [15,] 3.802083 3.985830
#> [16,] 4.142544 4.686235
#> TAGTTGGCATCAGTCA-300.1.3 TATCAGGTCCCACTTG-300.1.3
#> [1,] 4.437305 4.345583
#> [2,] 4.092951 4.414571
#> [3,] 4.198378 4.415216
#> [4,] 4.155958 4.437137
#> [5,] 4.457268 4.528691
#> [6,] 4.116032 4.577692
#> [7,] 4.457268 4.211476
#> [8,] 4.417342 4.808511
#> [9,] 4.187773 4.598968
#> [10,] 4.401747 4.333978
#> [11,] 4.168434 4.141199
#> [12,] 4.224579 4.555126
#> [13,] 4.301310 4.366860
#> [14,] 4.038054 4.245648
#> [15,] 4.194011 4.112186
#> [16,] 4.484092 4.597679
#> TATCTCACAGTCCTTC-300.1.3 TATTACCAGTGCTGCC-300.1.3
#> [1,] 4.740909 4.566702
#> [2,] 4.058586 3.954109
#> [3,] 3.995455 3.972252
#> [4,] 4.565657 4.104589
#> [5,] 4.636869 5.183031
#> [6,] 4.004545 4.238527
#> [7,] 4.106566 4.672892
#> [8,] 4.675758 4.411953
#> [9,] 4.352525 4.099253
#> [10,] 4.085354 3.962113
#> [11,] 3.990909 4.327641
#> [12,] 4.186364 3.955176
#> [13,] 4.173737 4.337247
#> [14,] 4.393434 4.094984
#> [15,] 4.128788 4.218783
#> [16,] 4.133838 4.374066
#> TATTACCCACGGTGTC-300.1.3 TCAACGAGTCGAACAG-300.1.3
#> [1,] 4.719885 4.256646
#> [2,] 3.444957 4.289366
#> [3,] 3.931988 4.289366
#> [4,] 3.937176 4.169734
#> [5,] 4.991931 4.516360
#> [6,] 4.224207 4.129857
#> [7,] 4.991354 4.067485
#> [8,] 4.202305 4.912065
#> [9,] 4.136023 4.153374
#> [10,] 3.791931 4.327198
#> [11,] 4.476657 4.226994
#> [12,] 4.102017 3.964213
#> [13,] 4.285303 4.621677
#> [14,] 4.186744 4.285276
#> [15,] 3.722190 3.943763
#> [16,] 3.951009 4.175869
#> TCAACGATCCTTTCTC-300.1.3 TCAATCTTCCTGTAGA-300.1.3
#> [1,] 4.543649 4.278173
#> [2,] 3.799538 3.837485
#> [3,] 3.963510 3.630486
#> [4,] 3.982448 3.792408
#> [5,] 5.290069 5.065836
#> [6,] 4.115012 3.909846
#> [7,] 5.203233 4.881376
#> [8,] 4.252194 4.578885
#> [9,] 4.245727 4.121590
#> [10,] 3.835104 3.623369
#> [11,] 3.910855 4.016014
#> [12,] 4.001848 3.652432
#> [13,] 4.341801 3.930605
#> [14,] 4.323788 4.620996
#> [15,] 3.599538 3.500593
#> [16,] 3.799538 3.763345
#> TCAGCAAAGTATCTCG-300.1.3 TCAGCTCAGCCCTAAT-300.1.3
#> [1,] 4.373455 4.241084
#> [2,] 3.783524 3.897290
#> [3,] 3.746453 3.990965
#> [4,] 4.380778 4.367095
#> [5,] 4.461785 4.680456
#> [6,] 3.745080 3.974798
#> [7,] 4.868192 5.116025
#> [8,] 4.297941 4.239658
#> [9,] 4.069565 4.051831
#> [10,] 3.959268 3.945792
#> [11,] 3.643478 4.304803
#> [12,] 3.738215 3.779838
#> [13,] 4.558352 4.223015
#> [14,] 4.100229 4.206372
#> [15,] 3.847597 3.671422
#> [16,] 4.397254 3.911555
#> TCAGCTCCACCGAAAG-300.1.3 TCGTACCAGAGGTAGA-300.1.3
#> [1,] 4.610128 4.119048
#> [2,] 3.498525 4.379121
#> [3,] 3.927729 4.531136
#> [4,] 4.123402 4.344322
#> [5,] 5.245329 4.691392
#> [6,] 3.979351 4.167582
#> [7,] 4.836283 4.755495
#> [8,] 3.926745 4.387363
#> [9,] 3.983776 4.590659
#> [10,] 3.924779 4.086996
#> [11,] 4.089971 4.420330
#> [12,] 3.838250 4.327839
#> [13,] 3.942970 4.057692
#> [14,] 4.383972 4.315934
#> [15,] 3.878564 4.159341
#> [16,] 4.090462 4.264652
#> TCGTAGAAGTGAAGTT-300.1.3 TCGTAGACACTGTTAG-300.1.3
#> [1,] 4.614431 4.399473
#> [2,] 3.493236 4.464074
#> [3,] 3.855130 4.615030
#> [4,] 4.317926 4.257746
#> [5,] 5.462232 4.462096
#> [6,] 3.911499 4.617666
#> [7,] 5.091883 4.222808
#> [8,] 4.002255 5.037574
#> [9,] 4.055242 5.109426
#> [10,] 3.760428 4.187212
#> [11,] 4.146561 4.379038
#> [12,] 3.988726 4.529334
#> [13,] 4.093010 4.279499
#> [14,] 4.477452 4.282136
#> [15,] 3.868095 4.382993
#> [16,] 4.050169 4.741595
#> TCTATTGTCGGAAACG-300.1.3 TCTCATATCTGTCAAG-300.1.3
#> [1,] 4.389405 4.744658
#> [2,] 4.100372 3.739178
#> [3,] 4.130112 4.021370
#> [4,] 3.986989 4.327671
#> [5,] 4.351301 4.827397
#> [6,] 4.080855 4.206575
#> [7,] 4.198885 4.407671
#> [8,] 4.973048 4.349041
#> [9,] 4.589219 4.243836
#> [10,] 4.468401 3.985753
#> [11,] 4.500929 4.137534
#> [12,] 4.291822 4.391781
#> [13,] 4.468401 4.401096
#> [14,] 3.960037 4.057534
#> [15,] 3.965613 3.954521
#> [16,] 4.468401 4.062466
#> TCTTTCCGTCGGATCC-300.1.3 TGAAAGACACGAAATA-300.1.3
#> [1,] 4.355343 4.689789
#> [2,] 3.719936 3.600444
#> [3,] 4.056459 3.781909
#> [4,] 4.297927 3.916759
#> [5,] 5.321212 4.872364
#> [6,] 3.916746 3.983907
#> [7,] 5.409888 4.721976
#> [8,] 4.262201 4.134295
#> [9,] 3.818501 4.137625
#> [10,] 3.872408 3.541065
#> [11,] 4.103668 4.132075
#> [12,] 3.988836 4.125416
#> [13,] 4.116108 4.078246
#> [14,] 4.314195 4.357381
#> [15,] 3.853907 3.753052
#> [16,] 3.835407 3.961154
#> TGACAACGTATAATGG-300.1.3 TGACAACTCATGTCTT-300.1.3
#> [1,] 4.134595 4.468380
#> [2,] 4.356467 3.961954
#> [3,] 4.348055 4.210797
#> [4,] 4.443743 4.356812
#> [5,] 4.371188 4.719794
#> [6,] 4.424816 4.258098
#> [7,] 4.303891 4.243702
#> [8,] 4.893796 4.424679
#> [9,] 4.390116 4.372751
#> [10,] 4.354364 4.289460
#> [11,] 4.145110 4.034961
#> [12,] 4.517350 4.044730
#> [13,] 4.652997 4.130591
#> [14,] 4.070452 4.247301
#> [15,] 4.027340 4.293059
#> [16,] 4.895899 4.170694
#> TGACGGCTCTACTTAC-300.1.3 TGACTAGGTCATATCG-300.1.3
#> [1,] 4.270683 4.534884
#> [2,] 4.133180 3.867682
#> [3,] 4.262035 4.288693
#> [4,] 4.206976 4.025662
#> [5,] 5.007207 4.583801
#> [6,] 4.184203 4.346431
#> [7,] 4.865091 4.532478
#> [8,] 4.518017 4.263031
#> [9,] 4.261747 4.186047
#> [10,] 4.270683 4.179631
#> [11,] 4.422600 4.585405
#> [12,] 4.111271 4.454691
#> [13,] 4.219948 4.326383
#> [14,] 4.452868 4.359262
#> [15,] 4.005765 3.690457
#> [16,] 4.042952 4.344828
#> TGAGAGGAGTTACCCA-300.1.3 TGAGGGAAGTGTTAGA-300.1.3
#> [1,] 4.453791 4.791892
#> [2,] 3.946873 3.974775
#> [3,] 4.000553 4.283784
#> [4,] 3.929164 3.931532
#> [5,] 5.078030 4.999099
#> [6,] 4.254566 3.379279
#> [7,] 4.702822 4.047748
#> [8,] 4.236303 4.968468
#> [9,] 4.031544 4.090991
#> [10,] 4.007194 3.554955
#> [11,] 4.042612 3.880180
#> [12,] 3.867183 3.887387
#> [13,] 4.213060 4.657658
#> [14,] 4.191478 4.234234
#> [15,] 4.080243 4.036036
#> [16,] 4.584394 4.478378
#> TGAGGGACACATGTGT-300.1.3 TGCACCTGTACAAGTA-300.1.3
#> [1,] 4.307355 4.343961
#> [2,] 3.881083 4.631884
#> [3,] 4.091840 4.226087
#> [4,] 4.205269 4.056039
#> [5,] 5.083059 4.839614
#> [6,] 4.075009 4.063768
#> [7,] 4.983535 4.860870
#> [8,] 4.346872 4.585507
#> [9,] 4.371021 4.169082
#> [10,] 4.272228 4.271498
#> [11,] 4.225393 4.266667
#> [12,] 4.251372 3.878261
#> [13,] 4.156239 4.107246
#> [14,] 4.294914 4.638647
#> [15,] 3.860959 4.079227
#> [16,] 4.213319 4.266667
#> TGCCCATTCTCGATGA-300.1.3 TGCGCAGGTCCGAAGA-300.1.3
#> [1,] 4.331525 4.484956
#> [2,] 4.013864 3.938559
#> [3,] 4.270344 3.996966
#> [4,] 4.218505 4.267762
#> [5,] 4.895419 5.159292
#> [6,] 4.046414 3.704678
#> [7,] 4.731766 4.984071
#> [8,] 4.317058 4.426802
#> [9,] 4.140145 4.050316
#> [10,] 4.020796 3.948167
#> [11,] 4.191682 4.105942
#> [12,] 4.363171 3.890518
#> [13,] 4.338156 4.262200
#> [14,] 4.247740 4.327939
#> [15,] 4.192586 4.055373
#> [16,] 4.218505 4.282174
#> TGCGTGGGTTGTGGAG-300.1.3 TGGCCAGCACTGTTAG-300.1.3
#> [1,] 4.692844 4.533390
#> [2,] 3.370353 3.777397
#> [3,] 4.006041 4.364726
#> [4,] 4.346654 4.541096
#> [5,] 5.081320 4.690068
#> [6,] 3.646375 4.220890
#> [7,] 4.765799 4.726884
#> [8,] 4.335037 4.389555
#> [9,] 3.922398 4.271404
#> [10,] 3.717472 3.837329
#> [11,] 3.694703 3.880993
#> [12,] 3.971190 3.946918
#> [13,] 4.095725 4.029110
#> [14,] 4.061338 3.967466
#> [15,] 4.362918 4.023116
#> [16,] 4.163569 4.144692
#> TGGCGCACATTTGCTT-300.1.3 TGGCGCAGTTTACTCT-300.1.3
#> [1,] 4.262849 4.423805
#> [2,] 4.158100 3.671315
#> [3,] 4.124096 3.790339
#> [4,] 4.063514 4.345120
#> [5,] 4.686144 5.432271
#> [6,] 4.004299 3.875498
#> [7,] 4.423295 5.008964
#> [8,] 4.402775 4.308765
#> [9,] 4.428767 4.137948
#> [10,] 4.131718 3.915339
#> [11,] 4.007231 4.120020
#> [12,] 4.458863 3.921813
#> [13,] 4.329490 4.128486
#> [14,] 4.238616 4.244024
#> [15,] 4.165331 3.750498
#> [16,] 4.362126 3.954681
#> TGGCTGGTCGTTGACA-300.1.3 TGGGCGTTCACAGTAC-300.1.3
#> [1,] 4.650741 4.640654
#> [2,] 3.592451 3.902454
#> [3,] 3.746297 3.738829
#> [4,] 4.202580 3.908118
#> [5,] 5.708075 5.017621
#> [6,] 3.711419 3.902454
#> [7,] 5.176780 4.587162
#> [8,] 4.188724 4.247325
#> [9,] 3.645485 4.156073
#> [10,] 3.630674 3.796728
#> [11,] 3.900143 4.181875
#> [12,] 3.857621 3.792952
#> [13,] 4.148591 4.292637
#> [14,] 4.042045 4.373820
#> [15,] 4.098423 4.006293
#> [16,] 4.521261 4.621145
#> TGGTTAGAGACCCACC-300.1.3 TGTCCCAAGAAAGTGG-300.1.3
#> [1,] 4.438009 4.911841
#> [2,] 3.662518 3.615385
#> [3,] 3.753949 3.878997
#> [4,] 4.196745 4.279602
#> [5,] 4.786979 5.176750
#> [6,] 3.894686 3.956785
#> [7,] 4.882240 4.968453
#> [8,] 4.247008 4.299481
#> [9,] 4.255146 3.990925
#> [10,] 3.803255 3.760156
#> [11,] 3.786979 4.150389
#> [12,] 3.697942 4.011668
#> [13,] 4.497367 4.239412
#> [14,] 4.132599 4.155143
#> [15,] 3.698899 3.914866
#> [16,] 4.075634 4.201383
#> TGTCCCACAAGCCATT-300.1.3 TGTGGTAAGGTTCCTA-300.1.3
#> [1,] 4.343495 4.239766
#> [2,] 4.259768 3.766082
#> [3,] 4.437956 4.046784
#> [4,] 4.182482 4.377193
#> [5,] 4.753542 4.876706
#> [6,] 4.021898 3.945419
#> [7,] 4.535852 4.981969
#> [8,] 4.333620 4.323587
#> [9,] 4.218549 3.945419
#> [10,] 4.142980 3.875731
#> [11,] 4.267067 3.915205
#> [12,] 4.386003 3.839669
#> [13,] 4.205238 4.375244
#> [14,] 4.381709 4.427388
#> [15,] 4.172606 3.712963
#> [16,] 4.300558 4.195419
#> TGTGGTACAATCACAC-300.1.3 TTAGGCAGTATTCTCT-300.1.3
#> [1,] 4.733266 4.188993
#> [2,] 3.489683 4.041999
#> [3,] 3.875692 4.123823
#> [4,] 4.345244 4.274439
#> [5,] 5.241570 4.758146
#> [6,] 3.798691 3.680666
#> [7,] 4.443885 4.702390
#> [8,] 4.112733 4.495293
#> [9,] 3.971314 4.211441
#> [10,] 3.578259 4.089066
#> [11,] 3.876195 4.233888
#> [12,] 4.000000 4.107169
#> [13,] 4.019124 4.347574
#> [14,] 4.324107 4.304127
#> [15,] 4.006039 4.169442
#> [16,] 4.349270 4.307024
#> TTAGTTCGTTGTCGCG-300.1.3 TTCCCAGGTTCAGCGC-300.1.3
#> [1,] 4.817686 4.757720
#> [2,] 3.871179 4.012352
#> [3,] 3.768013 4.060808
#> [4,] 4.105895 4.310689
#> [5,] 5.259825 4.961520
#> [6,] 3.906659 3.935392
#> [7,] 4.485262 4.417102
#> [8,] 4.227074 4.435154
#> [9,] 3.923035 3.952019
#> [10,] 3.803493 3.921615
#> [11,] 4.094432 4.021378
#> [12,] 3.846616 3.973872
#> [13,] 4.355895 4.233729
#> [14,] 4.284389 4.290261
#> [15,] 4.012009 4.121615
#> [16,] 4.510917 4.600950
#> TTCGGTCCAAGCGATG-300.1.3 TTCGGTCCACGGCTAC-300.1.3
#> [1,] 4.578608 4.426787
#> [2,] 3.775773 3.877863
#> [3,] 3.960052 4.063845
#> [4,] 4.094716 4.065232
#> [5,] 4.936856 5.083276
#> [6,] 3.994201 4.062457
#> [7,] 4.876933 5.170021
#> [8,] 4.166881 4.394171
#> [9,] 4.284149 4.040944
#> [10,] 3.965851 4.106176
#> [11,] 3.653351 4.164469
#> [12,] 3.847294 4.147814
#> [13,] 4.634665 4.259542
#> [14,] 4.098582 4.371270
#> [15,] 3.876933 3.770992
#> [16,] 4.102448 4.179736
#> TTCTCAACATGAAGTA-300.1.3 TTCTTAGTCAATCTCT-300.1.3
#> [1,] 4.546130 4.558630
#> [2,] 3.754799 3.964427
#> [3,] 4.091022 4.212780
#> [4,] 4.359752 4.055995
#> [5,] 5.105263 4.616601
#> [6,] 3.855108 3.980237
#> [7,] 4.769659 4.324111
#> [8,] 4.422291 4.514493
#> [9,] 4.027864 4.387352
#> [10,] 4.061920 3.897233
#> [11,] 3.718885 4.020422
#> [12,] 4.158514 4.208169
#> [13,] 4.426006 4.291831
#> [14,] 4.270588 3.928854
#> [15,] 4.287926 4.100791
#> [16,] 4.268111 4.403162
#> TTGAACGCATAAGACA-300.1.3 TTGTAGGTCTCCGGTT-300.1.3
#> [1,] 4.419804 4.410516
#> [2,] 4.080454 4.117713
#> [3,] 4.303765 4.252578
#> [4,] 4.148014 4.286677
#> [5,] 5.006189 4.949056
#> [6,] 4.036617 4.109239
#> [7,] 4.680763 4.829096
#> [8,] 4.178442 4.254416
#> [9,] 4.020629 4.297192
#> [10,] 3.962867 4.131700
#> [11,] 4.205776 4.247575
#> [12,] 4.028881 4.251046
#> [13,] 4.438370 4.321491
#> [14,] 4.131511 4.321286
#> [15,] 4.057246 3.981317
#> [16,] 4.406395 4.195202
#> TTTATGCTCTCTGTCG-300.1.3 TTTCCTCTCAGAGACG-300.1.3
#> [1,] 4.288357 4.889260
#> [2,] 4.041467 4.018012
#> [3,] 4.140670 3.895264
#> [4,] 4.110048 4.202135
#> [5,] 4.950239 5.106071
#> [6,] 4.125678 4.127418
#> [7,] 4.685486 4.305537
#> [8,] 4.371611 4.302869
#> [9,] 4.470494 4.136091
#> [10,] 4.113238 3.974650
#> [11,] 4.189155 4.120080
#> [12,] 4.148325 3.827885
#> [13,] 4.172249 4.128085
#> [14,] 4.428070 4.258172
#> [15,] 4.066348 3.991328
#> [16,] 4.201914 4.476318
#> TTTGGTTAGATCCCGC-300.1.3 AAACGGGGTGCCTGGT-400.2.1
#> [1,] 4.383838 4.199843
#> [2,] 3.913131 3.823276
#> [3,] 4.110101 4.193182
#> [4,] 4.289899 4.400470
#> [5,] 4.569697 5.098354
#> [6,] 4.037374 4.166536
#> [7,] 4.420202 5.074451
#> [8,] 4.507071 4.402038
#> [9,] 4.053535 4.127351
#> [10,] 3.882828 3.948668
#> [11,] 3.724242 4.065439
#> [12,] 3.772727 3.873041
#> [13,] 4.294949 4.171630
#> [14,] 4.229293 4.225313
#> [15,] 4.437374 3.822100
#> [16,] 4.170707 4.085815
#> AAAGATGGTGGCTCCA-400.2.1 AAAGCAATCGGTGTTA-400.2.1
#> [1,] 4.851917 4.109453
#> [2,] 3.673156 3.783227
#> [3,] 3.930383 4.054726
#> [4,] 4.259587 4.134328
#> [5,] 5.091445 5.132196
#> [6,] 3.923894 3.927505
#> [7,] 4.679056 4.935323
#> [8,] 4.339823 4.297086
#> [9,] 3.798820 3.803838
#> [10,] 3.738053 3.728500
#> [11,] 4.256637 4.023454
#> [12,] 3.663127 4.046908
#> [13,] 4.149263 4.153518
#> [14,] 4.008260 4.433547
#> [15,] 3.971681 4.000711
#> [16,] 4.312684 4.058991
#> AAAGTAGCAGACACTT-400.2.1 AAAGTAGGTTGGTAAA-400.2.1
#> [1,] 4.038730 4.382880
#> [2,] 4.190476 4.286003
#> [3,] 3.906667 4.023713
#> [4,] 4.241905 4.290052
#> [5,] 4.579683 4.905726
#> [6,] 4.322540 3.971082
#> [7,] 4.444444 4.521110
#> [8,] 4.594286 4.692019
#> [9,] 4.213968 4.175824
#> [10,] 4.158095 4.061018
#> [11,] 4.069206 4.173222
#> [12,] 4.200635 4.125217
#> [13,] 4.180952 4.088490
#> [14,] 4.101587 4.278195
#> [15,] 4.182857 4.158762
#> [16,] 4.506032 4.259109
#> AAATGCCCAGGACGTA-400.2.1 AAATGCCGTTATCGGT-400.2.1
#> [1,] 4.326405 4.346690
#> [2,] 3.869763 4.429443
#> [3,] 4.202014 4.209930
#> [4,] 4.120818 4.664634
#> [5,] 5.155570 4.267422
#> [6,] 3.904514 4.277875
#> [7,] 5.012342 4.467770
#> [8,] 4.464437 4.851916
#> [9,] 4.179929 4.639373
#> [10,] 3.795063 4.608014
#> [11,] 4.413121 4.275261
#> [12,] 4.265021 4.506969
#> [13,] 4.211432 4.590592
#> [14,] 4.250081 4.277875
#> [15,] 4.030205 4.130662
#> [16,] 4.253979 4.594948
#> AACACGTCATGCAACT-400.2.1 AACACGTTCGGAAACG-400.2.1
#> [1,] 4.453728 4.516367
#> [2,] 4.505141 5.112930
#> [3,] 3.931877 4.120295
#> [4,] 4.059126 4.096563
#> [5,] 4.186375 4.820786
#> [6,] 4.370180 4.186579
#> [7,] 3.943445 4.729951
#> [8,] 5.071979 4.552373
#> [9,] 4.579692 4.121931
#> [10,] 4.255784 4.120295
#> [11,] 3.885604 4.701309
#> [12,] 4.398458 4.459902
#> [13,] 4.780206 4.446809
#> [14,] 3.912596 4.837152
#> [15,] 4.186375 3.689034
#> [16,] 4.728792 4.193126
#> AACCATGAGGGTATCG-400.2.1 AACCGCGTCGTAGGAG-400.2.1
#> [1,] 4.368456 4.244038
#> [2,] 3.835570 4.149444
#> [3,] 3.908054 4.044515
#> [4,] 3.912081 4.149444
#> [5,] 4.895973 4.451510
#> [6,] 3.979195 4.156598
#> [7,] 4.740940 4.186010
#> [8,] 4.351678 4.773450
#> [9,] 4.267114 4.418124
#> [10,] 3.693289 4.070747
#> [11,] 4.431544 4.099364
#> [12,] 4.410067 3.992846
#> [13,] 4.237584 4.425278
#> [14,] 4.234228 4.042130
#> [15,] 3.771812 4.058029
#> [16,] 4.173826 4.704293
#> AACTCAGTCCCATTTA-400.2.1 AACTGGTTCCGCAAGC-400.2.1
#> [1,] 4.590123 4.540761
#> [2,] 4.161728 4.057971
#> [3,] 4.061728 4.226449
#> [4,] 4.023457 4.072464
#> [5,] 4.855556 5.017210
#> [6,] 4.416049 4.423913
#> [7,] 4.343210 4.302536
#> [8,] 4.939506 4.661232
#> [9,] 4.504938 4.338768
#> [10,] 4.198765 4.631341
#> [11,] 4.124691 4.238225
#> [12,] 4.902469 4.548007
#> [13,] 4.246914 4.413043
#> [14,] 3.976543 4.187500
#> [15,] 4.341975 4.546196
#> [16,] 4.755556 4.499094
#> AACTGGTTCTAACTGG-400.2.1 AAGACCTTCTTAGAGC-400.2.1
#> [1,] 4.322819 4.159115
#> [2,] 3.542282 3.966280
#> [3,] 4.169799 4.122761
#> [4,] 4.444966 3.936249
#> [5,] 4.775839 4.804004
#> [6,] 3.898658 3.863541
#> [7,] 5.053691 4.603793
#> [8,] 4.296644 4.341412
#> [9,] 4.139597 4.182824
#> [10,] 3.889933 3.966807
#> [11,] 4.204698 3.970495
#> [12,] 3.933557 4.165964
#> [13,] 4.146980 4.417808
#> [14,] 4.279195 4.095890
#> [15,] 3.692617 3.991043
#> [16,] 4.171812 4.253952
#> AAGCCGCTCGTAGATC-400.2.1 AAGGAGCCACATGACT-400.2.1
#> [1,] 4.494067 4.162257
#> [2,] 4.053937 4.008818
#> [3,] 3.802589 4.008818
#> [4,] 3.881338 4.282187
#> [5,] 4.631068 4.421517
#> [6,] 4.720604 4.227513
#> [7,] 3.916936 4.335097
#> [8,] 4.816613 4.505291
#> [9,] 4.901834 4.257496
#> [10,] 3.699029 4.473545
#> [11,] 4.230852 3.985009
#> [12,] 4.614887 4.192240
#> [13,] 4.922330 4.276014
#> [14,] 4.130529 4.284832
#> [15,] 3.586839 4.149030
#> [16,] 4.253506 4.689594
#> AAGGCAGCAGCCTTTC-400.2.1 AAGGCAGCAGTGAGTG-400.2.1
#> [1,] 4.513655 4.448928
#> [2,] 4.337185 4.056747
#> [3,] 4.093487 4.360656
#> [4,] 3.970588 4.350567
#> [5,] 4.298319 4.766709
#> [6,] 4.032563 3.856242
#> [7,] 3.836134 4.020177
#> [8,] 4.660714 4.891551
#> [9,] 4.356092 4.630517
#> [10,] 4.179622 4.194199
#> [11,] 4.162815 4.124842
#> [12,] 4.044118 4.283733
#> [13,] 4.566176 4.460277
#> [14,] 4.105042 4.219420
#> [15,] 3.837185 3.940731
#> [16,] 4.455882 4.486759
#> AAGTCTGTCTCGTATT-400.2.1 AATCCAGCACTGAAGG-400.2.1
#> [1,] 4.601865 4.233611
#> [2,] 3.995582 4.153754
#> [3,] 4.585174 4.216925
#> [4,] 4.222386 4.004768
#> [5,] 4.994109 4.796186
#> [6,] 4.110947 4.234803
#> [7,] 4.893471 4.219309
#> [8,] 4.124202 5.038141
#> [9,] 4.157094 4.803337
#> [10,] 3.952872 4.156138
#> [11,] 4.180658 4.156138
#> [12,] 4.150712 3.982122
#> [13,] 4.267550 4.653159
#> [14,] 3.994600 3.977354
#> [15,] 3.847815 4.081049
#> [16,] 4.050565 4.278903
#> AATCCAGGTTACGACT-400.2.1 AATCCAGTCTGCAGTA-400.2.1
#> [1,] 4.226655 4.531800
#> [2,] 4.465195 4.019847
#> [3,] 3.739389 4.396031
#> [4,] 4.045840 4.306721
#> [5,] 4.928693 5.026613
#> [6,] 3.800509 4.809653
#> [7,] 4.235993 4.154263
#> [8,] 4.959253 4.741092
#> [9,] 4.418506 4.697790
#> [10,] 3.887946 4.495264
#> [11,] 4.243633 4.694181
#> [12,] 3.810696 4.381146
#> [13,] 4.211375 3.899865
#> [14,] 4.525467 4.536761
#> [15,] 3.846350 4.110059
#> [16,] 4.375212 4.486243
#> ACACCCTAGTAGATGT-400.2.1 ACACCGGTCGTAGATC-400.2.1
#> [1,] 4.511864 4.574329
#> [2,] 3.637853 4.031182
#> [3,] 4.135593 4.086294
#> [4,] 4.001130 4.287165
#> [5,] 4.632203 4.799855
#> [6,] 4.049153 3.941987
#> [7,] 4.495480 4.414793
#> [8,] 4.602260 4.757070
#> [9,] 4.283616 4.074692
#> [10,] 3.871186 3.870921
#> [11,] 4.514689 3.787527
#> [12,] 4.367797 4.372734
#> [13,] 4.246328 4.110225
#> [14,] 3.999435 4.072516
#> [15,] 3.996045 4.208122
#> [16,] 4.038983 3.909355
#> ACACTGATCACGCGGT-400.2.1 ACACTGATCAGTTCGA-400.2.1
#> [1,] 4.540940 4.320030
#> [2,] 4.178523 4.230599
#> [3,] 4.143624 4.268293
#> [4,] 4.167785 4.341463
#> [5,] 4.476510 4.556541
#> [6,] 4.182550 4.467110
#> [7,] 4.148993 4.465632
#> [8,] 4.565101 4.552846
#> [9,] 4.076510 4.286031
#> [10,] 4.598658 4.188470
#> [11,] 4.210738 4.333333
#> [12,] 4.393289 4.308204
#> [13,] 4.366443 4.318551
#> [14,] 4.153020 4.190687
#> [15,] 4.370470 4.311899
#> [16,] 4.025503 4.441981
#> ACAGCCGAGCCTATGT-400.2.1 ACAGCCGGTGCTGTAT-400.2.1
#> [1,] 4.311938 4.573423
#> [2,] 4.332478 3.600782
#> [3,] 4.400513 3.868230
#> [4,] 4.089859 3.785036
#> [5,] 4.482670 5.071468
#> [6,] 4.187420 3.852596
#> [7,] 4.098845 4.998325
#> [8,] 4.680359 4.127862
#> [9,] 4.549422 4.236181
#> [10,] 4.319641 3.744277
#> [11,] 4.275995 4.016750
#> [12,] 4.421053 4.173088
#> [13,] 3.947368 4.131770
#> [14,] 4.326059 4.350084
#> [15,] 4.317073 3.793970
#> [16,] 4.373556 3.920715
#> ACATACGAGGGCTTCC-400.2.1 ACATACGGTGGGTATG-400.2.1
#> [1,] 4.489662 4.365367
#> [2,] 4.137218 3.769719
#> [3,] 4.231673 3.772439
#> [4,] 4.016447 3.863101
#> [5,] 4.885338 5.607434
#> [6,] 4.003289 4.000907
#> [7,] 4.326128 5.223935
#> [8,] 4.515038 4.274705
#> [9,] 4.134868 3.959202
#> [10,] 4.157895 4.021759
#> [11,] 4.310620 4.216682
#> [12,] 4.267857 3.959202
#> [13,] 4.169643 4.218495
#> [14,] 4.210996 4.322756
#> [15,] 4.275376 4.015413
#> [16,] 4.889098 4.339982
#> ACATACGTCTGTCCGT-400.2.1 ACATCAGAGATATGGT-400.2.1
#> [1,] 4.522907 4.356868
#> [2,] 3.832543 4.102696
#> [3,] 4.054239 4.228498
#> [4,] 4.481306 4.158537
#> [5,] 4.741969 4.948652
#> [6,] 3.880463 3.828626
#> [7,] 4.713533 4.707959
#> [8,] 4.314903 4.218228
#> [9,] 4.378094 3.973042
#> [10,] 3.807794 3.799743
#> [11,] 3.835176 4.179076
#> [12,] 4.352291 3.867137
#> [13,] 4.220642 4.347240
#> [14,] 3.982096 4.284981
#> [15,] 3.944181 4.137356
#> [16,] 4.023697 4.666239
#> ACATCAGGTTTGGCGC-400.2.1 ACATGGTCATTAGGCT-400.2.1
#> [1,] 4.260697 4.640279
#> [2,] 4.339303 3.785940
#> [3,] 4.350249 3.999367
#> [4,] 4.652736 4.267258
#> [5,] 4.483582 4.947435
#> [6,] 4.209950 3.948702
#> [7,] 3.994030 4.458518
#> [8,] 4.764179 4.615579
#> [9,] 4.193035 4.260925
#> [10,] 4.442786 3.706776
#> [11,] 4.150249 3.712476
#> [12,] 4.372139 4.322356
#> [13,] 4.631841 4.370488
#> [14,] 4.182090 4.154528
#> [15,] 4.281592 4.184927
#> [16,] 4.424876 4.172894
#> ACCCACTTCCTAGAAC-400.2.1 ACCTTTAGTACGACCC-400.2.1
#> [1,] 4.394433 4.263218
#> [2,] 4.191176 4.132184
#> [3,] 4.027311 4.463218
#> [4,] 4.112920 4.272414
#> [5,] 4.501050 4.203448
#> [6,] 4.358718 4.718391
#> [7,] 3.826155 4.082759
#> [8,] 5.245798 4.779310
#> [9,] 4.611345 4.785057
#> [10,] 4.033613 4.486207
#> [11,] 4.217962 4.495402
#> [12,] 4.226366 4.504598
#> [13,] 5.015231 4.528736
#> [14,] 4.270483 4.029885
#> [15,] 3.951681 4.165517
#> [16,] 4.158613 4.505747
#> ACGAGGACACGTCTCT-400.2.1 ACGCAGCAGCGGATCA-400.2.1
#> [1,] 4.254137 4.774663
#> [2,] 3.635343 3.621563
#> [3,] 3.963948 4.108356
#> [4,] 4.271868 4.353639
#> [5,] 4.676123 4.640970
#> [6,] 3.777187 4.256604
#> [7,] 5.252955 4.593531
#> [8,] 4.234043 4.516981
#> [9,] 4.312648 4.254987
#> [10,] 3.930851 3.968733
#> [11,] 4.101655 4.611321
#> [12,] 3.836288 4.415633
#> [13,] 4.393617 4.373585
#> [14,] 4.254728 4.298652
#> [15,] 3.689716 3.826415
#> [16,] 4.462175 4.029650
#> ACGCAGCCAAGTAATG-400.2.1 ACGCAGCTCTTTAGGG-400.2.1
#> [1,] 4.737593 4.781494
#> [2,] 3.790323 4.430323
#> [3,] 4.057692 3.906355
#> [4,] 4.354839 4.159420
#> [5,] 4.828164 4.584169
#> [6,] 4.288462 4.585284
#> [7,] 4.562655 4.404682
#> [8,] 4.614144 5.015608
#> [9,] 4.556452 4.603122
#> [10,] 4.037221 4.128205
#> [11,] 3.880273 4.273133
#> [12,] 4.132134 4.374582
#> [13,] 4.253102 4.612040
#> [14,] 4.395782 4.365663
#> [15,] 4.060174 3.908584
#> [16,] 4.276675 4.726867
#> ACGCCAGGTCCGTTAA-400.2.1 ACGCCGAAGAAGGGTA-400.2.1
#> [1,] 4.275701 4.398403
#> [2,] 4.657710 3.700290
#> [3,] 3.977804 3.619013
#> [4,] 3.929907 4.086357
#> [5,] 4.780374 5.037010
#> [6,] 4.233645 3.902032
#> [7,] 4.107477 4.772859
#> [8,] 4.693925 4.608128
#> [9,] 4.924065 4.203193
#> [10,] 4.408879 3.730044
#> [11,] 3.969626 3.638607
#> [12,] 4.643692 4.380987
#> [13,] 4.518692 4.433237
#> [14,] 4.316589 4.164006
#> [15,] 4.156542 3.787373
#> [16,] 4.793224 4.070392
#> ACGGAGACAAAGTCAA-400.2.1 ACGGAGAGTATAATGG-400.2.1
#> [1,] 4.609598 4.204715
#> [2,] 3.712062 4.285360
#> [3,] 4.037613 4.245658
#> [4,] 4.096628 4.187345
#> [5,] 5.226329 4.492556
#> [6,] 3.769780 4.434243
#> [7,] 4.942283 4.445409
#> [8,] 4.173152 4.758065
#> [9,] 3.902075 4.624069
#> [10,] 3.734112 4.346154
#> [11,] 3.835927 4.107940
#> [12,] 3.703632 4.549628
#> [13,] 4.192607 4.746898
#> [14,] 4.092088 3.858561
#> [15,] 4.062905 4.322581
#> [16,] 4.250973 4.526055
#> ACGGCCAGTTCCACAA-400.2.1 ACGGGTCGTGAAATCA-400.2.1
#> [1,] 4.462336 4.492602
#> [2,] 4.253275 4.465475
#> [3,] 4.094978 3.852035
#> [4,] 3.950328 4.101110
#> [5,] 4.846070 4.718866
#> [6,] 4.180131 4.450678
#> [7,] 4.260917 4.453144
#> [8,] 4.714520 4.736745
#> [9,] 4.112991 4.564118
#> [10,] 4.120087 4.381628
#> [11,] 4.056223 4.421085
#> [12,] 4.104258 4.686190
#> [13,] 4.147926 4.334155
#> [14,] 4.087336 4.217016
#> [15,] 4.231987 4.272503
#> [16,] 4.630459 4.622688
#> ACGGGTCGTGACGGTA-400.2.1 ACGGGTCTCATCGGAT-400.2.1
#> [1,] 4.596491 4.133612
#> [2,] 3.943320 3.802366
#> [3,] 4.305668 4.089770
#> [4,] 4.253036 4.086291
#> [5,] 4.918354 5.254697
#> [6,] 3.938596 3.740431
#> [7,] 4.633603 5.080028
#> [8,] 4.495277 4.425191
#> [9,] 4.333333 3.918580
#> [10,] 3.715924 3.776618
#> [11,] 4.180162 3.961030
#> [12,] 3.979082 4.139875
#> [13,] 4.072874 4.213640
#> [14,] 4.332659 4.171190
#> [15,] 3.838057 3.807933
#> [16,] 3.900135 4.213640
#> ACGTCAACAAGAGTCG-400.2.1 ACGTCAATCACTATTC-400.2.1
#> [1,] 4.464088 4.166859
#> [2,] 4.453039 4.305588
#> [3,] 4.278085 4.345279
#> [4,] 3.965009 4.007707
#> [5,] 5.165746 4.624277
#> [6,] 4.720074 3.933719
#> [7,] 4.350829 4.489403
#> [8,] 4.961326 4.643545
#> [9,] 4.402394 4.145665
#> [10,] 4.181400 4.310983
#> [11,] 4.649171 4.316378
#> [12,] 4.340700 4.356069
#> [13,] 4.346225 4.080154
#> [14,] 3.971455 4.331021
#> [15,] 3.752302 4.451638
#> [16,] 4.591160 4.354528
#> ACTATCTTCTCGCTTG-400.2.1 ACTGAACTCCGCAGTG-400.2.1
#> [1,] 4.454968 4.432165
#> [2,] 4.103064 4.205793
#> [3,] 4.250325 4.215701
#> [4,] 4.087465 4.069360
#> [5,] 4.749489 4.374238
#> [6,] 4.400371 4.618140
#> [7,] 4.265181 4.221799
#> [8,] 4.809471 4.768293
#> [9,] 4.532776 4.560213
#> [10,] 4.247539 4.258384
#> [11,] 4.219313 4.288110
#> [12,] 4.421541 4.321646
#> [13,] 4.458124 4.489329
#> [14,] 4.133148 4.491616
#> [15,] 4.283751 4.059451
#> [16,] 4.519591 4.935213
#> ACTGAGTTCTCATTCA-400.2.1 ACTGATGCAACTGGCC-400.2.1
#> [1,] 4.653666 4.496313
#> [2,] 3.819033 3.751475
#> [3,] 3.892356 3.978614
#> [4,] 4.365055 4.022124
#> [5,] 4.710608 4.952802
#> [6,] 4.035101 4.348083
#> [7,] 4.534321 4.702065
#> [8,] 4.378315 4.200590
#> [9,] 4.123245 4.186578
#> [10,] 4.053822 3.822271
#> [11,] 3.886895 4.373894
#> [12,] 3.850234 4.084808
#> [13,] 4.336193 4.173304
#> [14,] 4.047582 4.331121
#> [15,] 3.906396 3.820059
#> [16,] 4.589704 3.952065
#> ACTGCTCCAAGACGTG-400.2.1 ACTGCTCGTAATTGGA-400.2.1
#> [1,] 5.022195 4.604508
#> [2,] 4.256473 4.349385
#> [3,] 4.294698 4.007172
#> [4,] 4.342787 4.131148
#> [5,] 4.715166 4.919057
#> [6,] 4.237978 4.195697
#> [7,] 3.914920 4.171107
#> [8,] 4.906289 4.871926
#> [9,] 4.781751 4.872951
#> [10,] 4.208385 4.118852
#> [11,] 4.286067 4.079918
#> [12,] 4.266338 4.627049
#> [13,] 4.739827 4.793033
#> [14,] 4.287300 4.028689
#> [15,] 4.266338 3.922131
#> [16,] 4.366215 4.615779
#> ACTGTCCCAATGCCAT-400.2.1 ACTGTCCCAGCTTAAC-400.2.1
#> [1,] 4.837321 4.492865
#> [2,] 3.750239 3.798303
#> [3,] 4.026794 4.089472
#> [4,] 4.060287 3.967219
#> [5,] 4.917703 5.013884
#> [6,] 4.266029 3.954493
#> [7,] 4.565550 4.640956
#> [8,] 4.359809 4.497879
#> [9,] 4.288038 4.182414
#> [10,] 3.989474 3.709603
#> [11,] 4.355024 4.467798
#> [12,] 4.341627 4.125723
#> [13,] 4.496651 4.004628
#> [14,] 4.356938 4.394524
#> [15,] 4.049761 3.929425
#> [16,] 4.145455 4.181257
#> ACTGTCCCATCGGAAG-400.2.1 ACTTACTCAGCTGGCT-400.2.1
#> [1,] 4.220152 4.240060
#> [2,] 4.249788 4.077269
#> [3,] 4.418290 4.248312
#> [4,] 3.965284 4.096774
#> [5,] 4.386113 4.512378
#> [6,] 4.255715 4.180045
#> [7,] 4.246401 4.436609
#> [8,] 5.033023 4.402101
#> [9,] 4.388654 4.105026
#> [10,] 4.337003 4.117779
#> [11,] 4.320068 4.162041
#> [12,] 4.371719 4.220555
#> [13,] 4.725656 4.520630
#> [14,] 4.042337 4.078020
#> [15,] 4.198984 4.112528
#> [16,] 4.785775 4.225806
#> ACTTGTTCAAGGGTCA-400.2.1 ACTTTCACAGGCGATA-400.2.1
#> [1,] 4.586882 4.232861
#> [2,] 4.465077 4.334515
#> [3,] 3.804940 4.395981
#> [4,] 4.280239 4.048463
#> [5,] 4.344123 4.561466
#> [6,] 4.555366 4.150118
#> [7,] 4.183135 3.998818
#> [8,] 4.973595 4.658392
#> [9,] 4.833049 4.712766
#> [10,] 4.211244 3.952719
#> [11,] 4.183986 4.023641
#> [12,] 4.494889 4.430260
#> [13,] 4.514480 4.820331
#> [14,] 4.416525 3.973995
#> [15,] 3.932709 4.145390
#> [16,] 4.758092 4.445626
#> AGAGCTTTCCGTCATC-400.2.1 AGAGCTTTCTTGACGA-400.2.1
#> [1,] 4.398681 4.490584
#> [2,] 3.845940 4.031073
#> [3,] 4.018737 4.223164
#> [4,] 3.939625 4.169492
#> [5,] 4.973282 5.023540
#> [6,] 3.961485 4.129944
#> [7,] 4.378210 4.387947
#> [8,] 4.249133 4.535782
#> [9,] 4.044067 4.225047
#> [10,] 3.737335 3.979284
#> [11,] 4.064192 4.012241
#> [12,] 4.103053 4.164783
#> [13,] 4.247051 4.354049
#> [14,] 4.230049 4.030132
#> [15,] 3.808119 4.034840
#> [16,] 4.285566 4.551789
#> AGAGTGGCAGGCAGTA-400.2.1 AGATCTGGTATAGGTA-400.2.1
#> [1,] 4.551214 4.735632
#> [2,] 4.331573 3.610728
#> [3,] 4.117212 4.195402
#> [4,] 4.572334 4.236015
#> [5,] 4.329461 5.013027
#> [6,] 4.041183 3.974713
#> [7,] 4.732841 4.859004
#> [8,] 4.791975 4.289655
#> [9,] 4.601901 4.141762
#> [10,] 4.156283 3.691188
#> [11,] 4.255544 4.226820
#> [12,] 4.507920 4.105747
#> [13,] 4.892291 4.031418
#> [14,] 4.176346 4.012261
#> [15,] 3.976769 3.825287
#> [16,] 4.632524 3.802299
#> AGATTGCCAAGCGATG-400.2.1 AGCGGTCTCAAGATCC-400.2.1
#> [1,] 4.085256 4.514128
#> [2,] 4.098295 4.081323
#> [3,] 4.199599 3.942109
#> [4,] 4.089268 3.943487
#> [5,] 4.504514 5.157133
#> [6,] 4.158475 4.075121
#> [7,] 4.284855 4.427981
#> [8,] 4.385155 4.665748
#> [9,] 4.593781 4.025500
#> [10,] 3.935807 3.906272
#> [11,] 4.483450 3.929704
#> [12,] 4.507523 4.320469
#> [13,] 4.081244 4.353549
#> [14,] 3.756269 3.984838
#> [15,] 4.004012 4.112336
#> [16,] 4.472417 4.244659
#> AGCGTATTCGGATGGA-400.2.1 AGCGTATTCTCCCTGA-400.2.1
#> [1,] 4.339154 4.056911
#> [2,] 4.284007 4.383275
#> [3,] 4.234375 4.202091
#> [4,] 4.360294 4.314750
#> [5,] 4.578125 4.728223
#> [6,] 4.056985 4.196283
#> [7,] 4.091912 4.802555
#> [8,] 4.562500 4.571429
#> [9,] 4.375000 4.384437
#> [10,] 4.174632 4.289199
#> [11,] 4.279412 4.723577
#> [12,] 4.123162 4.840883
#> [13,] 4.374081 4.367015
#> [14,] 4.400735 4.074332
#> [15,] 4.071691 4.240418
#> [16,] 4.355699 4.405343
#> AGCTCCTGTAACGTTC-400.2.1 AGCTCTCAGATCCCAT-400.2.1
#> [1,] 4.454427 4.556038
#> [2,] 4.171875 3.567333
#> [3,] 4.139323 3.973067
#> [4,] 3.875000 4.144222
#> [5,] 4.596354 5.364031
#> [6,] 4.256510 3.780191
#> [7,] 4.061198 4.797567
#> [8,] 4.739583 4.225022
#> [9,] 4.897135 3.808862
#> [10,] 3.842448 3.837533
#> [11,] 3.975260 3.913119
#> [12,] 4.201823 3.896612
#> [13,] 4.869792 4.086881
#> [14,] 4.063802 4.125109
#> [15,] 3.998698 4.050391
#> [16,] 4.779948 3.992181
#> AGCTCTCGTATCACCA-400.2.1 AGCTTGACAGTCCTTC-400.2.1
#> [1,] 4.434866 4.173913
#> [2,] 4.531609 4.000000
#> [3,] 3.788314 4.200483
#> [4,] 4.133142 3.964976
#> [5,] 5.090996 4.719807
#> [6,] 4.160920 4.553140
#> [7,] 4.504789 4.483092
#> [8,] 4.716475 5.195652
#> [9,] 4.279693 4.721014
#> [10,] 4.406130 4.038647
#> [11,] 3.830460 4.339372
#> [12,] 4.333333 4.757246
#> [13,] 4.214559 4.320048
#> [14,] 3.788314 4.014493
#> [15,] 4.089080 4.146135
#> [16,] 4.681992 4.689614
#> AGCTTGACATCCTAGA-400.2.1 AGCTTGAGTACTCTCC-400.2.1
#> [1,] 4.235294 4.156463
#> [2,] 3.810160 4.479592
#> [3,] 3.863636 4.310091
#> [4,] 4.244207 3.981859
#> [5,] 4.894831 4.507937
#> [6,] 3.858289 3.925170
#> [7,] 5.051693 4.102608
#> [8,] 4.437611 4.845805
#> [9,] 4.474153 4.454082
#> [10,] 4.040107 4.086168
#> [11,] 4.211230 4.209751
#> [12,] 3.802139 4.240930
#> [13,] 4.283422 4.551587
#> [14,] 4.269162 4.243764
#> [15,] 3.596257 4.010771
#> [16,] 4.434938 4.445578
#> AGCTTGATCGCGGATC-400.2.1 AGGCCACCACACATGT-400.2.1
#> [1,] 4.282167 4.430818
#> [2,] 4.305869 4.228512
#> [3,] 3.972912 4.222222
#> [4,] 4.402935 4.341719
#> [5,] 4.630926 4.525157
#> [6,] 4.123025 4.358491
#> [7,] 4.455982 4.383648
#> [8,] 4.668172 4.753669
#> [9,] 4.420993 4.327044
#> [10,] 4.265237 4.436059
#> [11,] 4.207675 4.151992
#> [12,] 4.088036 4.597484
#> [13,] 4.554176 4.706499
#> [14,] 4.164786 3.969602
#> [15,] 4.054176 4.242138
#> [16,] 4.680587 4.447589
#> AGGCCGTGTAATTGGA-400.2.1 AGGCCGTGTTTGTGTG-400.2.1
#> [1,] 4.265440 4.521390
#> [2,] 4.697766 3.449198
#> [3,] 4.183968 3.848485
#> [4,] 4.273325 4.135472
#> [5,] 4.883049 5.026738
#> [6,] 4.306176 3.800357
#> [7,] 4.048620 4.506239
#> [8,] 4.931669 4.376114
#> [9,] 4.855453 4.656863
#> [10,] 4.428384 3.689840
#> [11,] 4.235217 3.832442
#> [12,] 4.248357 3.868984
#> [13,] 4.637319 4.357398
#> [14,] 4.197109 4.327094
#> [15,] 4.358739 3.697861
#> [16,] 4.756899 4.147950
#> AGGGAGTAGAATTGTG-400.2.1 AGGGTGATCGCCGTGA-400.2.1
#> [1,] 4.658683 4.012658
#> [2,] 4.098204 3.968776
#> [3,] 4.323353 3.794093
#> [4,] 3.938922 4.067511
#> [5,] 4.554491 5.383966
#> [6,] 4.101796 3.927426
#> [7,] 3.913772 4.818565
#> [8,] 4.792814 4.124895
#> [9,] 4.467066 4.319831
#> [10,] 4.063473 4.104641
#> [11,] 3.972455 3.843038
#> [12,] 4.102994 4.221941
#> [13,] 4.368862 4.268354
#> [14,] 4.100599 4.042194
#> [15,] 4.061078 3.997468
#> [16,] 4.475449 4.296203
#> AGGTCATAGACGCAAC-400.2.1 AGGTCCGCATCGGTTA-400.2.1
#> [1,] 4.824490 4.506202
#> [2,] 3.503061 3.934884
#> [3,] 3.683673 3.720155
#> [4,] 4.185714 3.864341
#> [5,] 4.874490 4.799225
#> [6,] 3.768367 3.986822
#> [7,] 4.705102 4.543411
#> [8,] 4.567347 4.486822
#> [9,] 4.179592 4.346512
#> [10,] 3.643878 3.369767
#> [11,] 3.750000 4.054264
#> [12,] 3.832653 3.783721
#> [13,] 4.611224 3.988372
#> [14,] 4.412245 4.457364
#> [15,] 3.559184 3.580620
#> [16,] 3.693878 4.423256
#> AGTAGTCAGAGTAAGG-400.2.1 AGTAGTCCACTTAAGC-400.2.1
#> [1,] 4.031679 4.179912
#> [2,] 4.587117 3.970199
#> [3,] 4.559662 4.026490
#> [4,] 4.000000 3.878587
#> [5,] 4.347413 4.442605
#> [6,] 4.051742 4.216336
#> [7,] 3.949314 4.094923
#> [8,] 5.011616 4.644592
#> [9,] 4.219641 4.697572
#> [10,] 4.126716 4.130243
#> [11,] 4.650475 3.993377
#> [12,] 4.325238 4.532009
#> [13,] 4.383316 4.270419
#> [14,] 4.311510 3.979029
#> [15,] 4.200634 4.312362
#> [16,] 4.422386 4.547461
#> AGTCTTTGTGAGTGAC-400.2.1 AGTGAGGAGGTGTGGT-400.2.1
#> [1,] 4.527561 4.491565
#> [2,] 3.652057 4.399651
#> [3,] 4.071793 4.021524
#> [4,] 4.040065 4.236184
#> [5,] 4.787308 4.540430
#> [6,] 3.923098 4.204188
#> [7,] 4.673837 4.317045
#> [8,] 4.311643 4.803374
#> [9,] 4.095994 4.477022
#> [10,] 3.865286 4.260617
#> [11,] 3.921753 4.506690
#> [12,] 4.212154 4.458406
#> [13,] 4.323474 4.384526
#> [14,] 4.009949 4.448517
#> [15,] 4.399570 3.958115
#> [16,] 4.301694 4.699244
#> AGTGGGACAGCTGTTA-400.2.1 AGTGGGAGTTGTTTGG-400.2.1
#> [1,] 4.408498 4.406125
#> [2,] 4.168518 4.557923
#> [3,] 4.254466 4.404794
#> [4,] 4.138580 3.997337
#> [5,] 4.597779 4.400799
#> [6,] 4.466924 4.233023
#> [7,] 4.301787 4.290280
#> [8,] 4.730082 4.838881
#> [9,] 4.374215 4.480692
#> [10,] 4.073877 4.424767
#> [11,] 4.173829 4.459387
#> [12,] 4.466924 4.643142
#> [13,] 4.267504 4.243675
#> [14,] 4.033800 4.089214
#> [15,] 4.186383 4.211718
#> [16,] 4.468373 4.310253
#> AGTGGGATCATCTGTT-400.2.1 AGTGTCAAGCGATTCT-400.2.1
#> [1,] 4.192448 5.019850
#> [2,] 4.177832 3.755901
#> [3,] 4.224117 3.981760
#> [4,] 4.347138 4.612661
#> [5,] 4.985384 4.973176
#> [6,] 4.587089 3.931330
#> [7,] 4.641900 4.325107
#> [8,] 4.539586 4.436159
#> [9,] 4.444580 3.853541
#> [10,] 4.096224 3.903970
#> [11,] 4.020706 4.042382
#> [12,] 4.095006 3.816524
#> [13,] 4.163216 4.052039
#> [14,] 4.352010 4.077790
#> [15,] 3.773447 4.037554
#> [16,] 4.389769 4.632511
#> AGTGTCAAGGCGATAC-400.2.1 AGTGTCAGTCTTGCGG-400.2.1
#> [1,] 4.206079 4.817909
#> [2,] 4.505167 3.635216
#> [3,] 4.202432 4.222356
#> [4,] 4.409726 4.242788
#> [5,] 4.381763 5.250000
#> [6,] 4.000608 3.817308
#> [7,] 4.203040 5.054688
#> [8,] 4.838298 4.272236
#> [9,] 4.879027 4.173077
#> [10,] 4.807295 3.986779
#> [11,] 4.056535 4.190505
#> [12,] 4.266261 3.948317
#> [13,] 4.224316 3.985577
#> [14,] 4.534954 4.484976
#> [15,] 4.586018 3.850962
#> [16,] 4.461398 3.795072
#> ATCATCTAGCCAACAG-400.2.1 ATCATCTGTCGTCTTC-400.2.1
#> [1,] 4.414017 4.296697
#> [2,] 4.277742 3.632918
#> [3,] 4.338092 3.695723
#> [4,] 4.408825 4.331890
#> [5,] 4.764439 4.885219
#> [6,] 4.198572 3.822415
#> [7,] 4.425698 5.258798
#> [8,] 4.855289 4.047645
#> [9,] 4.345879 4.083920
#> [10,] 4.142116 3.708717
#> [11,] 4.199870 4.017325
#> [12,] 4.136275 3.780726
#> [13,] 4.500324 4.334597
#> [14,] 4.179104 4.331348
#> [15,] 4.104478 3.667569
#> [16,] 4.370539 4.208446
#> ATCCACCAGTAGATGT-400.2.1 ATCCACCAGTGGTAGC-400.2.1
#> [1,] 4.786485 4.689753
#> [2,] 3.608196 4.240987
#> [3,] 3.703091 4.119545
#> [4,] 4.328541 4.220114
#> [5,] 4.984903 4.700190
#> [6,] 3.944644 4.021822
#> [7,] 4.692308 3.787476
#> [8,] 4.266715 4.600569
#> [9,] 4.488138 4.278937
#> [10,] 3.729691 3.909867
#> [11,] 3.762042 4.160342
#> [12,] 4.095615 4.240987
#> [13,] 4.442847 4.209677
#> [14,] 4.199856 4.235294
#> [15,] 3.861970 3.990512
#> [16,] 3.919482 4.605313
#> ATCGAGTTCTCCCTGA-400.2.1 ATCTACTTCGTCCAGG-400.2.1
#> [1,] 4.541089 4.740836
#> [2,] 4.002134 3.779421
#> [3,] 3.676628 4.174277
#> [4,] 3.975454 4.443730
#> [5,] 4.819637 5.251447
#> [6,] 3.913554 3.952412
#> [7,] 3.861259 4.612862
#> [8,] 4.813234 4.140193
#> [9,] 4.875133 4.072669
#> [10,] 4.002134 3.724116
#> [11,] 3.975454 4.161415
#> [12,] 4.330843 3.958199
#> [13,] 4.803629 4.091961
#> [14,] 3.877268 4.108682
#> [15,] 3.987193 3.853376
#> [16,] 4.505870 4.283601
#> ATGGGAGAGAGATGAG-400.2.1 ATGGGAGAGGCTATCT-400.2.1
#> [1,] 4.564719 4.055333
#> [2,] 4.515464 4.320667
#> [3,] 4.252005 4.186000
#> [4,] 4.003436 3.909333
#> [5,] 4.416953 4.508000
#> [6,] 4.129439 4.184000
#> [7,] 4.248568 4.192667
#> [8,] 4.403207 4.760667
#> [9,] 4.521191 4.755333
#> [10,] 4.151203 4.393333
#> [11,] 4.091638 4.366000
#> [12,] 4.734250 4.322667
#> [13,] 4.538373 4.498000
#> [14,] 4.103093 4.165333
#> [15,] 4.331042 3.874000
#> [16,] 4.542955 4.762667
#> ATGGGAGAGGGTCTCC-400.2.1 ATGTGTGGTAAACCTC-400.2.1
#> [1,] 4.445570 4.131851
#> [2,] 4.081857 4.368546
#> [3,] 4.307173 4.243050
#> [4,] 4.044726 4.131851
#> [5,] 5.202532 4.541700
#> [6,] 3.952743 4.197776
#> [7,] 4.741772 4.544877
#> [8,] 4.334177 4.652899
#> [9,] 4.115612 4.534551
#> [10,] 3.875105 4.407466
#> [11,] 4.064979 4.824464
#> [12,] 4.124051 4.693407
#> [13,] 4.363713 4.670373
#> [14,] 4.268354 4.093725
#> [15,] 4.075949 4.284353
#> [16,] 4.237975 4.763304
#> ATGTGTGTCTCAAACG-400.2.1 ATGTGTGTCTCTTATG-400.2.1
#> [1,] 4.853659 4.315888
#> [2,] 3.728659 4.149533
#> [3,] 3.873476 4.506542
#> [4,] 4.006098 4.107788
#> [5,] 5.167683 4.928349
#> [6,] 3.826982 4.798754
#> [7,] 4.211128 4.282866
#> [8,] 4.416921 4.976947
#> [9,] 4.067073 4.586293
#> [10,] 3.864329 4.411215
#> [11,] 4.000762 4.748910
#> [12,] 3.746189 4.275389
#> [13,] 4.326982 4.122118
#> [14,] 4.375762 4.673520
#> [15,] 3.970274 4.337072
#> [16,] 4.794207 4.658567
#> ATTCTACCAAGAAGAG-400.2.1 ATTCTACTCGTTGCCT-400.2.1
#> [1,] 4.175252 4.033383
#> [2,] 4.267637 4.277750
#> [3,] 4.090705 3.741490
#> [4,] 3.993281 3.886203
#> [5,] 4.403135 5.253906
#> [6,] 4.333147 3.851340
#> [7,] 4.300672 4.728663
#> [8,] 4.641657 4.547443
#> [9,] 4.397536 4.225785
#> [10,] 4.290594 3.937510
#> [11,] 4.152856 4.440224
#> [12,] 4.383539 4.167242
#> [13,] 4.464166 4.348462
#> [14,] 3.923852 4.386285
#> [15,] 3.941769 3.554021
#> [16,] 4.705487 4.333004
#> ATTGGACCAGGAACGT-400.2.1 ATTTCTGTCTCGATGA-400.2.1
#> [1,] 4.391328 4.241905
#> [2,] 4.171530 4.359048
#> [3,] 4.198255 4.220952
#> [4,] 4.119716 4.186667
#> [5,] 4.704800 4.319048
#> [6,] 4.139624 4.702857
#> [7,] 4.512817 4.356190
#> [8,] 4.415053 4.937143
#> [9,] 4.517317 4.961905
#> [10,] 4.080447 4.207619
#> [11,] 4.173030 4.686667
#> [12,] 4.279929 4.403810
#> [13,] 4.432506 4.437143
#> [14,] 4.175075 4.296190
#> [15,] 4.196618 4.105714
#> [16,] 4.391601 4.600000
#> CAACCAAAGGCATTGG-400.2.1 CAACCAATCGTGGGAA-400.2.1
#> [1,] 4.257703 4.344987
#> [2,] 4.262372 4.433024
#> [3,] 4.352007 4.514322
#> [4,] 4.332400 4.100674
#> [5,] 4.683473 4.316765
#> [6,] 4.220355 4.179023
#> [7,] 4.360411 4.259478
#> [8,] 4.420168 4.467565
#> [9,] 4.464052 4.160489
#> [10,] 4.330532 4.166386
#> [11,] 4.225957 4.468408
#> [12,] 4.453782 4.208509
#> [13,] 4.507937 4.175232
#> [14,] 3.859010 4.293597
#> [15,] 3.964519 4.192502
#> [16,] 4.768441 4.760741
#> CAACCTCGTGATAAAC-400.2.1 CAACTAGGTCGTGGCT-400.2.1
#> [1,] 4.308864 4.698457
#> [2,] 4.423823 3.809958
#> [3,] 3.818560 4.022440
#> [4,] 4.131579 4.137447
#> [5,] 5.206371 4.943899
#> [6,] 4.385042 3.839411
#> [7,] 4.011080 4.424965
#> [8,] 4.948753 4.348527
#> [9,] 4.901662 4.246844
#> [10,] 4.188366 3.950210
#> [11,] 4.155125 3.970547
#> [12,] 4.463989 3.989481
#> [13,] 4.680055 4.124825
#> [14,] 4.065097 4.161290
#> [15,] 3.826870 3.972651
#> [16,] 4.713296 4.384292
#> CAAGAAAAGTGTTAGA-400.2.1 CAAGAAAGTTACCAGT-400.2.1
#> [1,] 4.255802 4.504657
#> [2,] 4.010595 4.160881
#> [3,] 4.130676 4.287045
#> [4,] 4.032291 4.336156
#> [5,] 4.692230 4.215919
#> [6,] 4.271948 4.102456
#> [7,] 4.679617 4.469941
#> [8,] 4.288597 4.833192
#> [9,] 4.368315 4.533446
#> [10,] 4.082240 4.062659
#> [11,] 4.523209 4.240474
#> [12,] 4.219475 4.430991
#> [13,] 4.356206 4.763760
#> [14,] 3.950050 3.952583
#> [15,] 4.094854 4.301439
#> [16,] 4.188698 4.490262
#> CAAGAAAGTTAGGGTG-400.2.1 CAAGTTGCAGGCTGAA-400.2.1
#> [1,] 4.551872 4.819137
#> [2,] 3.717004 4.245041
#> [3,] 4.009822 4.164527
#> [4,] 4.069982 4.212369
#> [5,] 5.110497 4.690782
#> [6,] 3.766114 4.235706
#> [7,] 4.646409 3.773629
#> [8,] 4.400859 5.084014
#> [9,] 4.031921 4.669778
#> [10,] 3.826274 4.282380
#> [11,] 4.301412 4.138856
#> [12,] 4.135052 4.193699
#> [13,] 4.125230 4.864644
#> [14,] 4.197053 4.150525
#> [15,] 4.095150 4.030338
#> [16,] 4.314917 4.542590
#> CAAGTTGGTTGTTTGG-400.2.1 CACAAACAGTAGCCGA-400.2.1
#> [1,] 4.241123 4.285809
#> [2,] 4.004129 4.029980
#> [3,] 3.965318 3.992672
#> [4,] 3.878613 4.163225
#> [5,] 4.530140 4.865423
#> [6,] 3.975227 3.956029
#> [7,] 4.185797 5.028648
#> [8,] 4.656482 4.576949
#> [9,] 4.540875 4.266489
#> [10,] 3.742362 3.695536
#> [11,] 3.842279 4.364424
#> [12,] 4.022296 3.944704
#> [13,] 4.520231 4.162558
#> [14,] 4.122213 4.467022
#> [15,] 4.009083 3.583611
#> [16,] 4.473163 4.008661
#> CACAAACTCGATAGAA-400.2.1 CACACAAGTCCGAGTC-400.2.1
#> [1,] 4.325643 4.302103
#> [2,] 3.889382 4.356597
#> [3,] 3.931973 4.148184
#> [4,] 4.196096 4.031549
#> [5,] 5.459332 4.952199
#> [6,] 4.080745 4.231358
#> [7,] 4.921325 4.119503
#> [8,] 4.272996 5.127151
#> [9,] 4.132801 4.692161
#> [10,] 3.937001 4.466539
#> [11,] 4.074238 4.031549
#> [12,] 4.085478 4.802103
#> [13,] 4.196096 4.762906
#> [14,] 4.297249 4.168260
#> [15,] 3.878143 4.177820
#> [16,] 4.081337 4.208413
#> CACAGGCAGGCAGGTT-400.2.1 CACAGGCTCCCTCAGT-400.2.1
#> [1,] 4.657551 4.414166
#> [2,] 3.984542 3.876351
#> [3,] 4.262188 3.822329
#> [4,] 4.262782 4.336134
#> [5,] 4.457194 5.358944
#> [6,] 4.107610 3.821128
#> [7,] 4.539239 4.840336
#> [8,] 4.446492 4.272509
#> [9,] 4.071938 4.039616
#> [10,] 4.286564 3.855942
#> [11,] 4.233056 4.133253
#> [12,] 4.383472 4.109244
#> [13,] 3.911415 4.147659
#> [14,] 4.182521 4.384154
#> [15,] 4.085018 4.063625
#> [16,] 4.098692 3.743097
#> CACATAGTCACTTATC-400.2.1 CACATAGTCATTGCCC-400.2.1
#> [1,] 4.357771 4.452722
#> [2,] 4.103617 4.148042
#> [3,] 4.147605 4.246418
#> [4,] 4.501466 4.316141
#> [5,] 4.092864 5.104107
#> [6,] 4.054741 4.342884
#> [7,] 4.618768 4.222541
#> [8,] 4.572825 5.191977
#> [9,] 4.901271 4.981853
#> [10,] 4.436950 4.251194
#> [11,] 4.103617 4.315186
#> [12,] 4.599218 4.610315
#> [13,] 5.021505 4.811843
#> [14,] 4.131965 4.191022
#> [15,] 4.107527 4.130850
#> [16,] 4.373412 4.266476
#> CACATTTAGTTTAGGA-400.2.1 CACATTTCAGCCTATA-400.2.1
#> [1,] 4.788109 4.578518
#> [2,] 3.880455 3.792085
#> [3,] 3.943074 3.909548
#> [4,] 4.259962 4.224874
#> [5,] 4.891841 4.686558
#> [6,] 3.966477 4.263191
#> [7,] 4.207464 4.852387
#> [8,] 4.399747 4.591709
#> [9,] 4.225174 4.195352
#> [10,] 3.828590 3.990578
#> [11,] 4.032258 4.458543
#> [12,] 3.999367 4.047111
#> [13,] 4.313093 4.129397
#> [14,] 4.356104 4.444724
#> [15,] 4.201139 3.948492
#> [16,] 4.635041 4.146357
#> CACATTTGTCAGAGGT-400.2.1 CACCACTAGTACCGGA-400.2.1
#> [1,] 4.299745 4.347
#> [2,] 4.355867 4.664
#> [3,] 4.047194 4.310
#> [4,] 3.883929 4.678
#> [5,] 4.281888 4.864
#> [6,] 4.451531 4.462
#> [7,] 4.181122 4.363
#> [8,] 4.778061 5.340
#> [9,] 4.610969 4.586
#> [10,] 4.103316 4.462
#> [11,] 4.278061 4.563
#> [12,] 4.450255 4.685
#> [13,] 4.704082 4.070
#> [14,] 4.307398 4.298
#> [15,] 4.003827 4.432
#> [16,] 4.816327 4.032
#> CACCAGGCACGGTAGA-400.2.1 CACTCCACACCTCGGA-400.2.1
#> [1,] 4.293027 4.143105
#> [2,] 4.563989 4.741544
#> [3,] 4.500441 4.061578
#> [4,] 4.151809 4.295750
#> [5,] 4.512798 4.239376
#> [6,] 4.300088 4.123157
#> [7,] 4.089144 4.148309
#> [8,] 5.160635 5.036427
#> [9,] 4.511033 4.293148
#> [10,] 4.295675 4.340850
#> [11,] 4.346867 4.593235
#> [12,] 4.357458 4.249783
#> [13,] 4.332745 4.108413
#> [14,] 4.429832 4.856028
#> [15,] 4.112092 4.236774
#> [16,] 4.495146 4.607979
#> CAGAGAGAGCCAGAAC-400.2.1 CAGAGAGCACATGTGT-400.2.1
#> [1,] 4.241228 4.549965
#> [2,] 4.079622 4.139617
#> [3,] 3.985493 4.344437
#> [4,] 4.174089 4.289157
#> [5,] 5.040486 4.566265
#> [6,] 4.069163 4.172927
#> [7,] 4.932861 4.354359
#> [8,] 4.523954 4.652729
#> [9,] 4.100540 4.484054
#> [10,] 3.960189 4.356485
#> [11,] 4.311741 4.365698
#> [12,] 4.097166 4.644224
#> [13,] 4.239204 4.279943
#> [14,] 4.467949 3.836995
#> [15,] 3.986505 4.328845
#> [16,] 4.109312 4.424522
#> CAGAGAGTCCAAGCCG-400.2.1 CAGATCAAGAGCTTCT-400.2.1
#> [1,] 4.329268 4.306358
#> [2,] 4.350174 4.289017
#> [3,] 4.283101 4.505202
#> [4,] 4.103659 4.167630
#> [5,] 4.768293 4.764162
#> [6,] 4.217770 4.286705
#> [7,] 4.188153 4.401156
#> [8,] 4.967770 4.747977
#> [9,] 4.650697 4.900578
#> [10,] 4.484321 4.289017
#> [11,] 4.041812 4.319075
#> [12,] 4.662892 4.560694
#> [13,] 4.249129 4.902890
#> [14,] 4.207317 3.956069
#> [15,] 4.221254 4.245087
#> [16,] 4.779617 4.775723
#> CAGCAGCCATCACGAT-400.2.1 CAGCAGCGTGTCAATC-400.2.1
#> [1,] 4.379032 4.334075
#> [2,] 4.020968 3.943102
#> [3,] 4.087903 4.141449
#> [4,] 4.404839 4.051176
#> [5,] 4.687903 4.715194
#> [6,] 4.281452 4.267959
#> [7,] 4.407258 4.465989
#> [8,] 4.753226 4.528926
#> [9,] 4.204839 4.192308
#> [10,] 3.775000 4.008264
#> [11,] 4.208871 4.149078
#> [12,] 4.200806 4.129053
#> [13,] 4.242742 4.172600
#> [14,] 4.107258 4.246662
#> [15,] 4.039516 4.038462
#> [16,] 4.341935 4.236491
#> CAGCAGCGTTTGTTTC-400.2.1 CAGCATACACCAGGTC-400.2.1
#> [1,] 4.391331 4.251974
#> [2,] 4.333333 3.996711
#> [3,] 4.188645 4.003289
#> [4,] 4.073871 4.121711
#> [5,] 4.844933 5.371711
#> [6,] 4.808913 4.208553
#> [7,] 4.618437 5.238158
#> [8,] 4.743590 4.211842
#> [9,] 4.672772 4.151316
#> [10,] 4.242979 3.994079
#> [11,] 4.755189 3.993421
#> [12,] 4.464591 3.802632
#> [13,] 3.970696 4.387500
#> [14,] 4.058608 4.417763
#> [15,] 3.851648 3.837500
#> [16,] 4.463370 4.032895
#> CAGCATAGTGCCTGGT-400.2.1 CAGCCGAGTAGGGTAC-400.2.1
#> [1,] 4.136174 4.647674
#> [2,] 4.232420 3.461047
#> [3,] 4.098331 3.834884
#> [4,] 3.989869 3.941860
#> [5,] 5.189511 5.377326
#> [6,] 3.771752 3.752326
#> [7,] 4.881406 5.058721
#> [8,] 4.335518 4.287791
#> [9,] 4.092372 4.137209
#> [10,] 4.052741 3.616279
#> [11,] 4.399881 3.909884
#> [12,] 3.909714 3.908140
#> [13,] 4.282777 4.287209
#> [14,] 4.616508 4.470349
#> [15,] 3.798272 3.940116
#> [16,] 4.069726 4.166279
#> CAGCCGATCTCTAAGG-400.2.1 CAGCGACTCAGCACAT-400.2.1
#> [1,] 4.072848 4.172939
#> [2,] 4.327447 4.030466
#> [3,] 4.246505 4.333781
#> [4,] 4.125092 4.144265
#> [5,] 4.693893 4.521953
#> [6,] 4.251656 4.165323
#> [7,] 4.192789 4.409498
#> [8,] 4.983812 4.532706
#> [9,] 4.925681 4.301075
#> [10,] 4.370861 4.060484
#> [11,] 4.345843 4.134409
#> [12,] 4.413539 4.445789
#> [13,] 4.335541 4.163082
#> [14,] 4.288447 4.165323
#> [15,] 3.982340 4.410394
#> [16,] 4.872701 4.521953
#> CAGCGACTCAGTTCGA-400.2.1 CAGCTAAAGTGCGATG-400.2.1
#> [1,] 4.600400 4.367331
#> [2,] 4.384615 3.643405
#> [3,] 4.145854 3.914877
#> [4,] 4.204795 4.197086
#> [5,] 4.837163 5.154908
#> [6,] 4.402597 4.174847
#> [7,] 4.213786 5.246166
#> [8,] 5.123876 4.506135
#> [9,] 4.998002 4.061350
#> [10,] 3.981019 3.585123
#> [11,] 4.381618 4.375767
#> [12,] 4.491508 3.973160
#> [13,] 4.716284 4.154141
#> [14,] 4.176823 4.180215
#> [15,] 4.068931 3.614264
#> [16,] 4.657343 3.892638
#> CAGCTGGCACCATGTA-400.2.1 CAGCTGGGTTACGTCA-400.2.1
#> [1,] 4.619576 4.524164
#> [2,] 4.483350 3.707063
#> [3,] 4.180626 3.970260
#> [4,] 3.927346 4.098141
#> [5,] 4.739657 5.260223
#> [6,] 4.244198 3.952416
#> [7,] 4.086781 5.157621
#> [8,] 4.697275 3.995539
#> [9,] 4.908174 3.918216
#> [10,] 4.348133 3.846097
#> [11,] 4.212916 4.089219
#> [12,] 4.527750 3.949442
#> [13,] 4.392533 4.305576
#> [14,] 4.363269 4.250558
#> [15,] 3.913219 3.822305
#> [16,] 4.611504 4.411896
#> CAGCTGGTCCTCATTA-400.2.1 CAGGTGCCAAACGTGG-400.2.1
#> [1,] 4.181792 4.333333
#> [2,] 3.571053 4.194548
#> [3,] 4.127517 3.884758
#> [4,] 4.194631 4.153656
#> [5,] 5.060111 4.272615
#> [6,] 3.938722 4.431227
#> [7,] 5.325941 4.405204
#> [8,] 4.295886 4.747212
#> [9,] 4.572804 4.451053
#> [10,] 4.272250 3.830235
#> [11,] 4.377006 3.841388
#> [12,] 4.035308 4.044610
#> [13,] 4.092793 4.593556
#> [14,] 4.569886 4.484511
#> [15,] 3.583309 4.085502
#> [16,] 4.248906 4.548947
#> CAGGTGCTCGGTCTAA-400.2.1 CAGTAACGTCGAGATG-400.2.1
#> [1,] 4.641316 4.998198
#> [2,] 3.617970 3.675676
#> [3,] 4.069685 3.970571
#> [4,] 4.223205 4.971772
#> [5,] 4.911567 4.670270
#> [6,] 3.980898 3.832432
#> [7,] 4.620446 4.331532
#> [8,] 4.267421 4.527928
#> [9,] 4.302087 4.375976
#> [10,] 3.913336 3.890691
#> [11,] 4.114255 3.797598
#> [12,] 4.148567 4.087087
#> [13,] 4.167315 4.261862
#> [14,] 4.389459 3.936336
#> [15,] 3.948001 4.050450
#> [16,] 4.223912 3.977177
#> CAGTCCTTCAAACCGT-400.2.1 CATATGGCATCGGTTA-400.2.1
#> [1,] 4.219512 4.328680
#> [2,] 3.776423 4.256345
#> [3,] 3.754743 4.302030
#> [4,] 3.845528 4.101523
#> [5,] 5.638211 4.569797
#> [6,] 3.747290 4.390863
#> [7,] 5.708672 4.379442
#> [8,] 4.283198 4.835025
#> [9,] 3.826558 4.579949
#> [10,] 3.604336 4.284264
#> [11,] 4.090786 4.355330
#> [12,] 3.981707 4.600254
#> [13,] 4.002710 4.718274
#> [14,] 4.424119 4.173858
#> [15,] 3.674119 4.269036
#> [16,] 3.887534 4.458122
#> CATATTCCACCGATAT-400.2.1 CATATTCCACGGTAAG-400.2.1
#> [1,] 4.157390 4.743918
#> [2,] 4.410749 4.615877
#> [3,] 3.971209 4.215109
#> [4,] 3.992322 3.991037
#> [5,] 4.872361 4.568502
#> [6,] 4.396353 4.541613
#> [7,] 4.104607 4.426376
#> [8,] 4.730326 4.893726
#> [9,] 4.936660 4.674776
#> [10,] 4.246641 4.307298
#> [11,] 4.346449 4.211268
#> [12,] 4.677543 4.483995
#> [13,] 4.500000 4.554417
#> [14,] 4.250480 4.343150
#> [15,] 4.226488 4.208707
#> [16,] 4.718810 4.665813
#> CATCAGAAGGGTATCG-400.2.1 CATCAGACAATTCCTT-400.2.1
#> [1,] 4.666295 4.888889
#> [2,] 4.040179 4.212018
#> [3,] 3.791295 3.985261
#> [4,] 4.168527 4.072562
#> [5,] 4.738839 4.843537
#> [6,] 4.133929 4.385488
#> [7,] 4.455357 3.765306
#> [8,] 4.333705 5.045351
#> [9,] 3.827009 4.918367
#> [10,] 3.814732 4.377551
#> [11,] 4.248884 4.112245
#> [12,] 4.377232 4.400227
#> [13,] 3.963170 4.819728
#> [14,] 3.747768 4.083900
#> [15,] 4.051339 4.158730
#> [16,] 4.237723 4.349206
#> CATCCACAGGCCGAAT-400.2.1 CATCGAAAGTTATCGC-400.2.1
#> [1,] 4.413350 4.452642
#> [2,] 4.053273 4.512463
#> [3,] 4.162388 3.898305
#> [4,] 4.311297 3.809571
#> [5,] 4.916560 4.550349
#> [6,] 4.050064 4.349950
#> [7,] 4.243261 4.304088
#> [8,] 4.754814 5.063809
#> [9,] 4.099487 4.541376
#> [10,] 4.078306 4.392822
#> [11,] 4.133504 4.529412
#> [12,] 4.202182 4.363908
#> [13,] 4.601412 4.340977
#> [14,] 3.886393 3.887338
#> [15,] 4.229782 3.901296
#> [16,] 4.252888 4.270189
#> CATCGGGTCAGTTGAC-400.2.1 CATGACAGTGAAAGAG-400.2.1
#> [1,] 4.516018 4.341601
#> [2,] 4.213959 4.510710
#> [3,] 4.258581 4.091319
#> [4,] 4.263158 4.073281
#> [5,] 4.608696 4.524239
#> [6,] 4.138444 4.440812
#> [7,] 3.764302 4.129651
#> [8,] 4.767735 4.837655
#> [9,] 5.310069 4.209696
#> [10,] 3.990847 4.264938
#> [11,] 4.360412 4.188275
#> [12,] 4.551487 4.244645
#> [13,] 4.740275 4.481398
#> [14,] 4.281465 4.220970
#> [15,] 3.821510 4.308906
#> [16,] 4.749428 4.614431
#> CATGCCTAGCGATTCT-400.2.1 CATGCCTCAGCGTCCA-400.2.1
#> [1,] 4.421687 4.524788
#> [2,] 4.384337 4.118501
#> [3,] 4.362651 4.074970
#> [4,] 4.093976 4.269649
#> [5,] 4.554217 4.389359
#> [6,] 4.403614 4.567110
#> [7,] 4.275904 4.331318
#> [8,] 4.849398 4.742443
#> [9,] 4.620482 4.442563
#> [10,] 4.503614 4.201935
#> [11,] 4.345783 4.316808
#> [12,] 4.303614 4.437727
#> [13,] 4.613253 4.848851
#> [14,] 4.390361 4.337364
#> [15,] 4.133735 4.200726
#> [16,] 4.619277 4.328900
#> CATGCCTGTCGAGTTT-400.2.1 CATTATCCAAATTGCC-400.2.1
#> [1,] 4.268145 4.530169
#> [2,] 3.712702 4.309831
#> [3,] 3.884073 4.147119
#> [4,] 3.994960 4.168136
#> [5,] 4.164315 4.801356
#> [6,] 5.117944 4.202034
#> [7,] 3.940524 4.356610
#> [8,] 4.609879 5.155932
#> [9,] 4.699597 4.538983
#> [10,] 3.847782 4.040000
#> [11,] 3.966734 4.208136
#> [12,] 4.393145 4.552542
#> [13,] 4.158266 4.738983
#> [14,] 5.019153 4.309153
#> [15,] 3.759073 4.254915
#> [16,] 4.959677 4.489492
#> CATTATCCATAGACTC-400.2.1 CATTATCGTTTCCACC-400.2.1
#> [1,] 4.734549 4.647887
#> [2,] 4.300912 4.098592
#> [3,] 4.107396 4.264588
#> [4,] 4.218845 4.626761
#> [5,] 4.564336 4.542254
#> [6,] 4.531915 4.779678
#> [7,] 4.294833 4.232394
#> [8,] 5.022290 5.157948
#> [9,] 4.882472 4.987928
#> [10,] 4.284701 4.102616
#> [11,] 3.981763 4.209256
#> [12,] 4.372847 4.394366
#> [13,] 4.753799 4.355131
#> [14,] 4.252280 4.735412
#> [15,] 3.997974 4.060362
#> [16,] 4.485309 4.574447
#> CATTCGCAGGCATGTG-400.2.1 CATTCGCAGGTGCTAG-400.2.1
#> [1,] 4.383065 4.707061
#> [2,] 4.529234 4.384542
#> [3,] 4.310484 4.181298
#> [4,] 4.167339 4.112595
#> [5,] 4.621976 4.576336
#> [6,] 4.656250 4.503817
#> [7,] 4.401210 4.305344
#> [8,] 5.230847 4.873092
#> [9,] 4.909274 4.361641
#> [10,] 4.105847 4.236641
#> [11,] 4.430444 4.344466
#> [12,] 4.502016 4.397901
#> [13,] 4.415323 4.564885
#> [14,] 4.098790 3.916031
#> [15,] 3.881048 4.132634
#> [16,] 4.565524 4.500000
#> CATTCGCCAAAGTGCG-400.2.1 CATTCGCCAAGCCTAT-400.2.1
#> [1,] 4.363821 4.197011
#> [2,] 3.525407 3.900815
#> [3,] 4.057927 4.190217
#> [4,] 4.100610 4.048007
#> [5,] 4.887195 4.731431
#> [6,] 4.407520 3.960598
#> [7,] 4.553862 4.510417
#> [8,] 4.217480 4.359149
#> [9,] 4.403455 4.395380
#> [10,] 3.628049 4.161232
#> [11,] 4.518293 4.081522
#> [12,] 4.279472 4.241848
#> [13,] 4.024390 4.121377
#> [14,] 4.168699 4.241395
#> [15,] 3.966463 4.108243
#> [16,] 3.943089 4.183424
#> CATTCGCCAGAGTGTG-400.2.1 CCACCTACAATCCGAT-400.2.1
#> [1,] 4.493603 4.222093
#> [2,] 3.940741 4.227907
#> [3,] 4.125253 4.148837
#> [4,] 4.168350 3.997674
#> [5,] 4.797306 4.387209
#> [6,] 3.939394 4.527907
#> [7,] 4.104377 4.193023
#> [8,] 5.022222 4.501163
#> [9,] 4.030303 4.973256
#> [10,] 3.867340 4.154651
#> [11,] 4.242424 4.425581
#> [12,] 4.027609 4.941860
#> [13,] 4.232323 4.626744
#> [14,] 4.238384 4.322093
#> [15,] 4.293603 4.337209
#> [16,] 4.349495 4.769767
#> CCACGGAGTGTGCGTC-400.2.1 CCACTACCACAGCGTC-400.2.1
#> [1,] 4.183922 4.305055
#> [2,] 4.213155 3.670014
#> [3,] 4.209501 3.981648
#> [4,] 4.672351 4.323407
#> [5,] 4.409257 5.326870
#> [6,] 4.104750 3.968837
#> [7,] 4.604141 5.101454
#> [8,] 4.711328 4.283241
#> [9,] 4.682095 4.071676
#> [10,] 4.383678 3.949446
#> [11,] 4.376370 4.239266
#> [12,] 4.453106 3.931094
#> [13,] 4.915956 4.259695
#> [14,] 3.987820 4.264197
#> [15,] 4.181486 3.847645
#> [16,] 4.705238 4.016274
#> CCACTACTCACATACG-400.2.1 CCAGCGACATTGGCGC-400.2.1
#> [1,] 4.290297 4.551440
#> [2,] 3.782277 3.469136
#> [3,] 3.558140 4.189986
#> [4,] 3.932237 4.135117
#> [5,] 5.657578 4.954733
#> [6,] 4.062550 3.841564
#> [7,] 5.494787 4.766804
#> [8,] 4.154771 4.342936
#> [9,] 4.065357 4.431413
#> [10,] 3.878909 3.913580
#> [11,] 3.936247 4.106996
#> [12,] 3.865678 3.987654
#> [13,] 4.197273 4.126200
#> [14,] 4.277867 4.262003
#> [15,] 3.508019 3.890261
#> [16,] 4.016840 4.401920
#> CCAGCGATCGGAATCT-400.2.1 CCAGCGATCTCTTGAT-400.2.1
#> [1,] 4.157951 4.148867
#> [2,] 4.075623 4.629989
#> [3,] 4.049075 3.932039
#> [4,] 4.153124 4.037756
#> [5,] 5.226602 4.539374
#> [6,] 4.318316 4.229773
#> [7,] 4.968088 4.508091
#> [8,] 4.476535 4.478964
#> [9,] 4.217485 4.320388
#> [10,] 4.187182 4.647249
#> [11,] 4.267096 4.149946
#> [12,] 3.919013 4.363538
#> [13,] 4.210780 4.187702
#> [14,] 4.238938 4.130529
#> [15,] 3.751676 4.690399
#> [16,] 4.271118 4.870550
#> CCATGTCCAGGGAGAG-400.2.1 CCATGTCGTCAAACTC-400.2.1
#> [1,] 4.655708 4.202387
#> [2,] 3.690377 4.112859
#> [3,] 3.917513 3.737927
#> [4,] 4.246264 4.423766
#> [5,] 4.663479 4.805209
#> [6,] 4.100418 4.326099
#> [7,] 4.277944 4.670646
#> [8,] 4.184698 4.600109
#> [9,] 4.525403 4.357569
#> [10,] 3.989839 4.045035
#> [11,] 3.865511 4.085187
#> [12,] 4.272564 4.094411
#> [13,] 4.104603 4.411286
#> [14,] 4.338314 4.372762
#> [15,] 3.969516 4.224634
#> [16,] 3.861327 4.148128
#> CCATTCGAGCCGATTT-400.2.1 CCATTCGGTGCTGTAT-400.2.1
#> [1,] 4.437653 4.219313
#> [2,] 4.185819 4.038513
#> [3,] 4.270171 4.084614
#> [4,] 4.562347 4.238664
#> [5,] 4.579462 5.001897
#> [6,] 4.275061 4.138494
#> [7,] 3.828851 4.915766
#> [8,] 4.525672 4.591918
#> [9,] 4.336186 4.210397
#> [10,] 4.088020 4.025422
#> [11,] 4.147922 4.193512
#> [12,] 4.635697 4.099981
#> [13,] 4.630807 4.177765
#> [14,] 4.501222 4.258964
#> [15,] 4.224939 3.883893
#> [16,] 4.790954 4.102637
#> CCCAATCTCGTACGGC-400.2.1 CCCAGTTAGACTTGAA-400.2.1
#> [1,] 4.298446 4.443347
#> [2,] 4.494685 4.038867
#> [3,] 4.390842 4.013175
#> [4,] 4.387572 4.348485
#> [5,] 4.638594 4.706851
#> [6,] 4.376124 3.996047
#> [7,] 4.290270 4.183794
#> [8,] 4.898610 4.770751
#> [9,] 4.559280 4.399868
#> [10,] 4.176615 3.922925
#> [11,] 4.461161 4.221344
#> [12,] 4.188062 4.042819
#> [13,] 4.518397 4.385375
#> [14,] 3.881439 3.919631
#> [15,] 4.254293 4.077075
#> [16,] 4.708913 4.712121
#> CCGGGATTCACTTACT-400.2.1 CCGGTAGCACAGACTT-400.2.1
#> [1,] 4.115198 4.510338
#> [2,] 3.897386 4.578947
#> [3,] 3.953533 4.316729
#> [4,] 4.026137 4.641917
#> [5,] 5.219748 4.416353
#> [6,] 3.851888 4.595865
#> [7,] 4.989351 4.327068
#> [8,] 4.410455 5.106203
#> [9,] 4.114230 4.567669
#> [10,] 3.783156 4.732143
#> [11,] 4.227493 4.562030
#> [12,] 3.875121 4.313910
#> [13,] 3.887706 4.512218
#> [14,] 4.447241 4.421992
#> [15,] 3.577928 4.114662
#> [16,] 3.919652 4.307331
#> CCGGTAGGTGAGGCTA-400.2.1 CCGTACTAGAGAACAG-400.2.1
#> [1,] 4.458490 4.643070
#> [2,] 4.462255 3.798063
#> [3,] 4.460273 4.006706
#> [4,] 4.557163 3.878539
#> [5,] 4.711116 5.412072
#> [6,] 4.309095 3.965723
#> [7,] 4.821478 4.988823
#> [8,] 4.291064 4.193741
#> [9,] 4.299188 4.096870
#> [10,] 4.398256 3.902385
#> [11,] 4.269467 3.872578
#> [12,] 4.323757 3.979136
#> [13,] 4.329503 4.278689
#> [14,] 4.328512 4.209389
#> [15,] 4.278779 4.111773
#> [16,] 4.424609 4.291356
#> CCGTACTAGTTCGATC-400.2.1 CCGTACTTCTATCCCG-400.2.1
#> [1,] 4.070088 4.212567
#> [2,] 4.349186 4.034759
#> [3,] 4.349186 4.033422
#> [4,] 4.235294 4.196524
#> [5,] 4.489362 4.610963
#> [6,] 4.359199 4.215241
#> [7,] 4.262829 4.323529
#> [8,] 4.782228 4.585561
#> [9,] 4.967459 4.564171
#> [10,] 4.320401 4.125668
#> [11,] 4.349186 4.171123
#> [12,] 4.558198 4.659091
#> [13,] 4.178974 4.338235
#> [14,] 4.399249 4.185829
#> [15,] 4.135169 4.303476
#> [16,] 4.546934 4.717914
#> CCGTGGAGTATCTGCA-400.2.1 CCGTTCAGTTCCGTCT-400.2.1
#> [1,] 4.316667 4.346541
#> [2,] 4.298958 4.089296
#> [3,] 4.272917 4.219397
#> [4,] 4.379167 4.128326
#> [5,] 4.278125 4.968658
#> [6,] 4.640625 3.830869
#> [7,] 4.597917 4.630396
#> [8,] 5.167708 4.435245
#> [9,] 4.803125 4.292135
#> [10,] 4.109375 4.013601
#> [11,] 4.361458 4.005914
#> [12,] 4.761458 4.201656
#> [13,] 4.563542 4.333530
#> [14,] 4.111458 4.147250
#> [15,] 4.379167 4.208752
#> [16,] 4.269792 4.649320
#> CCTACACCATTGCGGC-400.2.1 CCTACACGTTCATGGT-400.2.1
#> [1,] 4.104256 4.558758
#> [2,] 4.070285 4.109756
#> [3,] 3.764936 4.243902
#> [4,] 4.171027 4.073171
#> [5,] 5.256931 4.593126
#> [6,] 3.789145 4.050998
#> [7,] 5.258102 4.191242
#> [8,] 4.456072 4.597007
#> [9,] 4.158532 4.236696
#> [10,] 3.712222 4.047118
#> [11,] 4.302226 4.016630
#> [12,] 3.787193 4.221729
#> [13,] 4.249512 4.466741
#> [14,] 4.668879 4.002772
#> [15,] 3.659508 4.231153
#> [16,] 3.994143 4.478936
#> CCTACACTCGCACTCT-400.2.1 CCTACACTCTTGTCAT-400.2.1
#> [1,] 4.585239 4.231768
#> [2,] 4.054054 4.110889
#> [3,] 4.167360 4.160839
#> [4,] 4.065489 4.409590
#> [5,] 4.673597 4.237762
#> [6,] 4.462578 4.042957
#> [7,] 3.782744 4.505495
#> [8,] 4.994802 4.617383
#> [9,] 4.804574 4.386613
#> [10,] 4.436590 4.140859
#> [11,] 4.246362 4.221778
#> [12,] 4.662162 4.492507
#> [13,] 4.650728 4.523477
#> [14,] 4.067568 4.069930
#> [15,] 4.039501 4.351648
#> [16,] 4.748441 4.295704
#> CCTACCAGTACGAAAT-400.2.1 CCTACCATCTAACTGG-400.2.1
#> [1,] 4.454251 4.300761
#> [2,] 3.870445 3.908629
#> [3,] 4.067206 4.060914
#> [4,] 4.400000 4.388325
#> [5,] 4.609717 4.200508
#> [6,] 4.166802 4.300761
#> [7,] 4.902024 4.675127
#> [8,] 4.143320 4.766497
#> [9,] 4.489879 3.893401
#> [10,] 3.974089 3.964467
#> [11,] 4.089069 4.167513
#> [12,] 3.845344 3.961929
#> [13,] 4.221862 4.096447
#> [14,] 4.477733 4.175127
#> [15,] 3.717409 3.723350
#> [16,] 4.167611 4.312183
#> CCTATTATCTCTTGAT-400.2.1 CCTCAGTAGCAGCCTC-400.2.1
#> [1,] 4.201710 4.302648
#> [2,] 3.788229 3.758313
#> [3,] 3.907445 3.802032
#> [4,] 4.147887 4.160099
#> [5,] 5.508048 5.522167
#> [6,] 3.940644 4.012931
#> [7,] 5.120724 5.271860
#> [8,] 4.172535 4.309113
#> [9,] 3.878270 3.989840
#> [10,] 3.923038 3.930111
#> [11,] 4.041247 4.022167
#> [12,] 4.191650 4.049569
#> [13,] 4.352616 4.088362
#> [14,] 4.307344 4.354680
#> [15,] 3.803320 3.921182
#> [16,] 4.283702 3.931958
#> CCTCAGTAGTGCGTGA-400.2.1 CCTCAGTTCAGGCAAG-400.2.1
#> [1,] 4.607962 4.099364
#> [2,] 4.139676 4.276630
#> [3,] 4.020918 4.120032
#> [4,] 3.977733 4.372814
#> [5,] 5.322537 4.825119
#> [6,] 3.956140 4.259141
#> [7,] 4.325911 4.739269
#> [8,] 4.495951 4.054849
#> [9,] 3.883941 4.258347
#> [10,] 3.754386 4.087440
#> [11,] 4.336707 4.325119
#> [12,] 4.182861 4.268680
#> [13,] 4.131579 4.337838
#> [14,] 4.265857 4.323529
#> [15,] 4.213225 3.826709
#> [16,] 4.639676 4.286169
#> CCTTCCCGTGGCCCTA-400.2.1 CCTTCGACATAGGATA-400.2.1
#> [1,] 4.495589 4.545655
#> [2,] 3.751403 3.629263
#> [3,] 4.307137 3.767877
#> [4,] 4.323176 4.325083
#> [5,] 4.951885 5.473597
#> [6,] 3.903769 4.096810
#> [7,] 4.510826 5.337184
#> [8,] 4.472334 4.090209
#> [9,] 4.506014 4.108361
#> [10,] 3.916600 3.800330
#> [11,] 3.863673 4.123212
#> [12,] 4.377706 3.918042
#> [13,] 4.315156 4.015952
#> [14,] 4.239775 4.293729
#> [15,] 4.044908 3.710671
#> [16,] 3.982358 3.974697
#> CCTTCGAGTATGCTTG-400.2.1 CGAACATGTAGCGTGA-400.2.1
#> [1,] 4.428344 4.730627
#> [2,] 4.355626 3.280443
#> [3,] 4.108280 3.812862
#> [4,] 4.469745 4.459673
#> [5,] 4.388535 5.071165
#> [6,] 4.375796 3.764365
#> [7,] 4.282909 4.820242
#> [8,] 4.760616 4.122826
#> [9,] 4.469214 4.377965
#> [10,] 4.293524 3.532947
#> [11,] 4.141189 3.760148
#> [12,] 4.530255 4.098050
#> [13,] 4.535032 4.409594
#> [14,] 4.096603 4.131787
#> [15,] 4.414013 3.864523
#> [16,] 4.561040 3.954665
#> CGAACATTCTCAAGTG-400.2.1 CGACTTCAGTAGATGT-400.2.1
#> [1,] 4.423168 4.362339
#> [2,] 4.375887 4.086676
#> [3,] 4.323089 4.270224
#> [4,] 4.241135 4.438137
#> [5,] 3.995272 4.932019
#> [6,] 4.548463 4.751869
#> [7,] 4.504334 4.179130
#> [8,] 4.980299 4.712441
#> [9,] 4.674547 4.775663
#> [10,] 4.225374 4.349762
#> [11,] 4.457841 4.373895
#> [12,] 4.649330 4.518015
#> [13,] 4.576832 4.229096
#> [14,] 4.030733 4.432699
#> [15,] 4.093775 4.174031
#> [16,] 4.666667 4.392250
#> CGACTTCAGTCGCCGT-400.2.1 CGAGAAGTCCGCAAGC-400.2.1
#> [1,] 4.629339 4.254572
#> [2,] 3.833147 3.943648
#> [3,] 3.568869 4.200198
#> [4,] 4.059351 4.270391
#> [5,] 5.097424 5.001977
#> [6,] 3.975364 3.800791
#> [7,] 4.568869 4.637173
#> [8,] 4.587906 4.315373
#> [9,] 4.173572 4.073159
#> [10,] 3.368421 3.971824
#> [11,] 4.241881 4.067721
#> [12,] 3.773796 4.438952
#> [13,] 3.800672 4.192289
#> [14,] 4.310190 4.185863
#> [15,] 3.525196 4.161147
#> [16,] 4.127660 4.216510
#> CGAGCACGTACAGTTC-400.2.1 CGAGCACTCCTAGAAC-400.2.1
#> [1,] 4.563750 4.395817
#> [2,] 3.456250 4.235720
#> [3,] 3.865000 4.433628
#> [4,] 4.048750 4.189059
#> [5,] 4.781875 4.901046
#> [6,] 4.163125 4.122285
#> [7,] 4.725625 4.460981
#> [8,] 4.121875 4.867257
#> [9,] 4.349375 4.284795
#> [10,] 3.773125 4.395012
#> [11,] 4.164375 4.131134
#> [12,] 4.131250 4.712792
#> [13,] 4.186250 4.355591
#> [14,] 4.167500 4.150442
#> [15,] 3.831250 4.353982
#> [16,] 4.114375 4.473854
#> CGAGCCAAGGTCATCT-400.2.1 CGATCGGGTGCTTCTC-400.2.1
#> [1,] 4.414726 4.341325
#> [2,] 3.606311 3.782334
#> [3,] 3.691210 3.878864
#> [4,] 4.417731 4.205678
#> [5,] 5.256198 4.690852
#> [6,] 3.945905 4.211987
#> [7,] 4.998497 4.651104
#> [8,] 4.435011 4.459937
#> [9,] 4.063862 4.171609
#> [10,] 3.790383 3.962776
#> [11,] 3.986476 3.936278
#> [12,] 4.001503 3.731861
#> [13,] 4.305034 4.459937
#> [14,] 4.194591 4.129968
#> [15,] 3.626597 3.750158
#> [16,] 3.872276 4.259306
#> CGATGGCAGATCCGAG-400.2.1 CGATGGCAGGTGATTA-400.2.1
#> [1,] 4.491062 4.282568
#> [2,] 3.701893 4.300818
#> [3,] 3.525237 4.101951
#> [4,] 3.543638 4.443046
#> [5,] 5.282334 4.542480
#> [6,] 4.098318 4.099434
#> [7,] 5.383807 4.148521
#> [8,] 4.166667 4.563247
#> [9,] 3.928496 4.645689
#> [10,] 4.003680 4.269981
#> [11,] 4.179285 4.176841
#> [12,] 3.941640 4.398993
#> [13,] 4.080967 4.521712
#> [14,] 4.217140 4.042165
#> [15,] 3.735542 4.379484
#> [16,] 3.924816 4.602895
#> CGATGTACAAGTTAAG-400.2.1 CGATGTAGTATGAAAC-400.2.1
#> [1,] 4.258065 4.327609
#> [2,] 4.281907 3.936163
#> [3,] 4.246143 4.100454
#> [4,] 3.990182 4.145820
#> [5,] 4.628331 5.107583
#> [6,] 4.279804 3.936487
#> [7,] 4.397616 4.769281
#> [8,] 4.700561 4.369086
#> [9,] 4.471248 4.141607
#> [10,] 4.316971 3.953338
#> [11,] 4.372370 4.256643
#> [12,] 4.511921 4.334413
#> [13,] 4.145161 4.252430
#> [14,] 4.114306 4.303305
#> [15,] 4.136045 4.256319
#> [16,] 4.256662 4.261180
#> CGATGTATCAAGGCTT-400.2.1 CGATGTATCTTTCCTC-400.2.1
#> [1,] 4.476031 4.711554
#> [2,] 3.948718 3.996675
#> [3,] 4.268673 4.063175
#> [4,] 3.933110 4.231920
#> [5,] 5.199554 4.722361
#> [6,] 3.614270 4.210308
#> [7,] 4.853958 4.397340
#> [8,] 4.414716 4.486284
#> [9,] 4.297659 4.367415
#> [10,] 3.738016 3.937656
#> [11,] 4.410256 4.350790
#> [12,] 4.180602 4.330008
#> [13,] 4.319955 4.277639
#> [14,] 4.355630 4.310889
#> [15,] 4.071349 4.011638
#> [16,] 4.847269 4.112219
#> CGCGTTTGTCACACGC-400.2.1 CGCGTTTTCACCTCGT-400.2.1
#> [1,] 4.356389 4.287160
#> [2,] 4.366940 4.098833
#> [3,] 4.249707 4.416342
#> [4,] 4.189918 4.221790
#> [5,] 4.384525 4.837354
#> [6,] 4.180539 3.992218
#> [7,] 4.422040 4.578988
#> [8,] 4.661196 4.256809
#> [9,] 4.887456 4.381323
#> [10,] 3.919109 3.822568
#> [11,] 4.406800 3.949416
#> [12,] 4.574443 4.533074
#> [13,] 4.480657 4.190661
#> [14,] 4.140680 4.125292
#> [15,] 4.162954 4.129961
#> [16,] 5.018757 4.431907
#> CGGACACCAATAGAGT-400.2.1 CGGACGTAGGTGATTA-400.2.1
#> [1,] 4.482456 4.498775
#> [2,] 4.139254 3.764706
#> [3,] 3.986842 3.944240
#> [4,] 3.984649 3.774510
#> [5,] 4.800439 4.965686
#> [6,] 4.452851 3.947304
#> [7,] 4.177632 4.847426
#> [8,] 5.350877 4.326593
#> [9,] 5.442982 3.987745
#> [10,] 3.911184 3.679534
#> [11,] 4.652412 4.447917
#> [12,] 4.696272 4.306985
#> [13,] 4.861842 4.105392
#> [14,] 3.736842 4.338848
#> [15,] 3.775219 3.828431
#> [16,] 4.365132 3.932598
#> CGGACTGAGACGCTTT-400.2.1 CGGACTGTCTGGTGTA-400.2.1
#> [1,] 4.521142 4.510345
#> [2,] 4.583510 4.531034
#> [3,] 4.117336 4.431034
#> [4,] 4.136364 4.093103
#> [5,] 4.540169 4.750575
#> [6,] 4.201903 4.447126
#> [7,] 4.410148 4.524138
#> [8,] 4.960888 5.155172
#> [9,] 4.534884 4.619540
#> [10,] 4.485201 4.006897
#> [11,] 4.329810 4.135632
#> [12,] 4.910148 4.293103
#> [13,] 4.345666 4.218391
#> [14,] 4.236786 4.250575
#> [15,] 4.231501 4.327586
#> [16,] 4.911205 4.233333
#> CGGAGTCAGTCAAGGC-400.2.1 CGGAGTCCACACATGT-400.2.1
#> [1,] 4.666436 4.589947
#> [2,] 4.221685 3.972222
#> [3,] 4.275552 4.025132
#> [4,] 4.175414 4.031746
#> [5,] 4.900552 5.194444
#> [6,] 4.064227 4.120370
#> [7,] 3.973757 4.908730
#> [8,] 5.091851 3.796296
#> [9,] 4.011050 4.174603
#> [10,] 3.868785 3.859788
#> [11,] 4.398481 4.473545
#> [12,] 3.950276 4.324074
#> [13,] 4.336326 4.537037
#> [14,] 4.052486 4.468254
#> [15,] 3.979972 3.804233
#> [16,] 4.314917 3.932540
#> CGGCTAGCAGCTGTTA-400.2.1 CGGGTCACATCGATTG-400.2.1
#> [1,] 4.499466 4.880130
#> [2,] 4.233725 4.403888
#> [3,] 4.139808 4.044276
#> [4,] 4.399146 4.018359
#> [5,] 4.503735 4.732181
#> [6,] 4.272145 4.778618
#> [7,] 4.624333 4.355292
#> [8,] 4.956243 4.828294
#> [9,] 4.824973 4.334773
#> [10,] 4.082177 4.656587
#> [11,] 4.341515 4.298056
#> [12,] 4.297759 4.347732
#> [13,] 4.483458 4.496760
#> [14,] 4.058698 4.077754
#> [15,] 4.475987 4.272138
#> [16,] 4.438634 4.183585
#> CGTAGCGTCATTATCC-400.2.1 CGTCACTAGTGACTCT-400.2.1
#> [1,] 4.218750 4.262372
#> [2,] 4.454688 4.349206
#> [3,] 4.450781 3.944911
#> [4,] 4.297656 4.437908
#> [5,] 4.707031 4.513539
#> [6,] 4.477344 4.392157
#> [7,] 4.137500 4.231559
#> [8,] 4.904688 5.323063
#> [9,] 4.362500 4.900093
#> [10,] 4.182031 4.347339
#> [11,] 4.329688 4.616246
#> [12,] 4.366406 4.715219
#> [13,] 4.302344 4.468721
#> [14,] 4.401563 4.169935
#> [15,] 4.101563 4.228758
#> [16,] 4.728125 4.479925
#> CGTCTACCACGAAGCA-400.2.1 CGTGTAACAAGCGTAG-400.2.1
#> [1,] 4.498845 4.519841
#> [2,] 4.200924 3.431746
#> [3,] 3.952656 4.139683
#> [4,] 4.245958 4.265873
#> [5,] 4.192841 5.029365
#> [6,] 4.448037 4.017460
#> [7,] 4.452656 4.637302
#> [8,] 4.845266 4.319841
#> [9,] 4.697460 4.098413
#> [10,] 4.078522 3.879365
#> [11,] 4.170901 3.796032
#> [12,] 4.423788 3.942063
#> [13,] 4.495381 4.215079
#> [14,] 4.299076 4.467460
#> [15,] 4.130485 3.888889
#> [16,] 4.595843 3.934127
#> CGTTCTGAGACTAAGT-400.2.1 CGTTCTGCACCAGATT-400.2.1
#> [1,] 4.528894 4.268895
#> [2,] 3.870666 3.915698
#> [3,] 4.082554 3.981105
#> [4,] 4.237755 4.217297
#> [5,] 4.899285 4.856105
#> [6,] 4.082554 4.030523
#> [7,] 4.454045 4.629360
#> [8,] 4.594937 4.388808
#> [9,] 4.269675 4.295058
#> [10,] 3.882223 4.167151
#> [11,] 3.844249 4.064680
#> [12,] 4.463952 4.228198
#> [13,] 4.410017 4.268895
#> [14,] 4.098514 4.310320
#> [15,] 4.396808 3.919331
#> [16,] 4.476059 4.235465
#> CTAACTTAGGATCGCA-400.2.1 CTAAGACGTAGGCTGA-400.2.1
#> [1,] 4.361298 4.224033
#> [2,] 4.350112 4.148676
#> [3,] 3.986577 3.978615
#> [4,] 4.069351 4.156823
#> [5,] 4.781879 4.461303
#> [6,] 4.063758 4.374745
#> [7,] 3.975391 4.374745
#> [8,] 4.747204 4.968432
#> [9,] 4.807606 4.647658
#> [10,] 4.402685 4.162933
#> [11,] 4.275168 4.558045
#> [12,] 4.724832 4.725051
#> [13,] 4.621924 4.553971
#> [14,] 4.087248 4.046843
#> [15,] 4.380313 4.137475
#> [16,] 4.645414 4.467413
#> CTAATGGCATTTGCTT-400.2.1 CTACACCAGCTGCGAA-400.2.1
#> [1,] 4.259077 4.539144
#> [2,] 3.762462 3.778593
#> [3,] 3.668308 4.061468
#> [4,] 3.808615 4.181040
#> [5,] 5.321231 4.641896
#> [6,] 3.932308 3.991131
#> [7,] 5.182769 4.346177
#> [8,] 4.216615 4.213456
#> [9,] 4.136000 4.159021
#> [10,] 3.681846 3.966361
#> [11,] 3.874462 4.011009
#> [12,] 3.853538 4.538226
#> [13,] 4.096000 4.355352
#> [14,] 4.630769 4.086850
#> [15,] 3.521231 4.153517
#> [16,] 3.830154 4.413150
#> CTACATTTCAGAGACG-400.2.1 CTACCCAAGCCACTAT-400.2.1
#> [1,] 4.631776 4.236817
#> [2,] 3.976947 4.088207
#> [3,] 4.226168 3.973154
#> [4,] 4.316511 4.592522
#> [5,] 4.568224 4.602109
#> [6,] 3.999377 4.233941
#> [7,] 4.140810 4.630872
#> [8,] 4.697819 4.603068
#> [9,] 4.284112 4.650048
#> [10,] 4.287850 4.435283
#> [11,] 4.103427 4.112176
#> [12,] 4.082866 4.265580
#> [13,] 4.066667 4.921381
#> [14,] 4.146417 3.979866
#> [15,] 4.423053 4.118888
#> [16,] 4.152025 4.668265
#> CTACCCAAGCCCAGCT-400.2.1 CTACCCACAGGTCGTC-400.2.1
#> [1,] 4.902878 4.772078
#> [2,] 3.449640 3.885246
#> [3,] 3.922062 3.782655
#> [4,] 3.970024 4.294553
#> [5,] 4.871703 4.597567
#> [6,] 3.828537 4.213644
#> [7,] 4.395683 4.313062
#> [8,] 4.297362 4.698043
#> [9,] 4.286571 4.406134
#> [10,] 3.245803 3.695928
#> [11,] 4.164269 4.114225
#> [12,] 4.056355 4.278160
#> [13,] 4.251799 4.598625
#> [14,] 4.414868 4.041777
#> [15,] 3.758993 4.038075
#> [16,] 4.372902 4.286092
#> CTACCCATCTTCTGGC-400.2.1 CTACGTCGTACGCACC-400.2.1
#> [1,] 4.090663 3.946860
#> [2,] 4.355886 4.101449
#> [3,] 4.392422 4.477053
#> [4,] 4.115020 3.989130
#> [5,] 4.500677 4.571256
#> [6,] 4.005413 4.264493
#> [7,] 3.993234 3.940821
#> [8,] 4.947226 4.509662
#> [9,] 4.453315 4.458937
#> [10,] 4.595399 4.219807
#> [11,] 3.879567 4.379227
#> [12,] 4.147497 4.173913
#> [13,] 4.027064 3.931159
#> [14,] 4.326116 3.948068
#> [15,] 4.104195 4.088164
#> [16,] 4.349120 4.624396
#> CTACGTCGTAGGACAC-400.2.1 CTACGTCGTATGAAAC-400.2.1
#> [1,] 4.236420 4.401693
#> [2,] 3.642007 3.594544
#> [3,] 3.924987 3.642521
#> [4,] 4.002069 4.087488
#> [5,] 4.870667 5.404516
#> [6,] 3.739783 3.730950
#> [7,] 4.894982 5.092192
#> [8,] 4.385929 4.073377
#> [9,] 4.003104 3.927563
#> [10,] 3.814278 3.911571
#> [11,] 3.825660 4.020696
#> [12,] 4.177962 3.994356
#> [13,] 4.590274 4.408278
#> [14,] 4.307294 4.313264
#> [15,] 4.279876 3.730950
#> [16,] 4.067770 3.950141
#> CTAGAGTAGAGGTAGA-400.2.1 CTAGCCTTCTGCAAGT-400.2.1
#> [1,] 4.000000 4.381829
#> [2,] 4.125786 3.719379
#> [3,] 4.072327 3.940771
#> [4,] 4.183438 4.133410
#> [5,] 4.230608 4.568143
#> [6,] 4.241090 4.029327
#> [7,] 4.271488 4.723979
#> [8,] 4.574423 4.165612
#> [9,] 4.635220 4.288097
#> [10,] 4.060797 3.795860
#> [11,] 4.110063 4.057504
#> [12,] 4.408805 4.046578
#> [13,] 4.702306 4.256469
#> [14,] 4.207547 4.506613
#> [15,] 3.982180 3.834963
#> [16,] 4.719078 3.914319
#> CTCAGAAAGACATAAC-400.2.1 CTCAGAAGTTACGGAG-400.2.1
#> [1,] 4.444204 4.416667
#> [2,] 4.496208 4.384615
#> [3,] 4.145179 4.465201
#> [4,] 4.242687 4.501832
#> [5,] 4.208017 4.801282
#> [6,] 4.111593 4.670330
#> [7,] 3.994583 4.224359
#> [8,] 4.906826 5.235348
#> [9,] 4.872156 4.720696
#> [10,] 4.406284 4.637363
#> [11,] 4.445287 4.473443
#> [12,] 4.360780 4.652015
#> [13,] 4.674973 4.260989
#> [14,] 3.911159 4.163919
#> [15,] 4.187432 4.315018
#> [16,] 4.632719 4.361722
#> CTCCTAGTCGGCTTGG-400.2.1 CTCCTAGTCTTGTTTG-400.2.1
#> [1,] 4.492857 4.446512
#> [2,] 4.141964 4.095349
#> [3,] 4.314286 4.333721
#> [4,] 4.226786 4.430233
#> [5,] 5.122321 4.968605
#> [6,] 4.098214 4.402326
#> [7,] 4.723214 4.001163
#> [8,] 4.424107 4.848837
#> [9,] 4.275000 4.837209
#> [10,] 3.952679 4.348837
#> [11,] 4.157143 4.340698
#> [12,] 4.198214 4.805814
#> [13,] 4.454464 4.656977
#> [14,] 4.216071 3.924419
#> [15,] 4.252679 3.847674
#> [16,] 4.326786 4.417442
#> CTCGAAACAAGGTGTG-400.2.1 CTCGAAACAGCCAGAA-400.2.1
#> [1,] 4.396198 4.525050
#> [2,] 3.742966 4.230461
#> [3,] 4.099620 4.315631
#> [4,] 4.276046 3.994990
#> [5,] 4.946008 4.632265
#> [6,] 4.090494 4.108216
#> [7,] 4.646388 3.914830
#> [8,] 4.307985 5.084168
#> [9,] 4.409886 4.415832
#> [10,] 3.898859 4.147295
#> [11,] 3.998479 4.171343
#> [12,] 3.990114 4.515030
#> [13,] 4.577947 4.939880
#> [14,] 4.201521 3.868737
#> [15,] 3.990875 4.015030
#> [16,] 4.243346 4.364729
#> CTCGAAAGTTCGCGAC-400.2.1 CTCGAGGCATTCGACA-400.2.1
#> [1,] 4.155751 4.496259
#> [2,] 4.158946 4.399002
#> [3,] 4.121406 4.471322
#> [4,] 4.148562 4.256858
#> [5,] 4.865016 4.605985
#> [6,] 4.310703 4.531172
#> [7,] 4.091853 4.467581
#> [8,] 4.991214 4.781796
#> [9,] 4.691693 4.584788
#> [10,] 4.219649 4.265586
#> [11,] 4.205272 4.032419
#> [12,] 4.486422 4.356608
#> [13,] 4.099042 4.410224
#> [14,] 4.218051 3.990025
#> [15,] 4.136581 4.051122
#> [16,] 4.863419 4.692020
#> CTCGGAGAGTTCGCAT-400.2.1 CTCGGAGGTCCGAATT-400.2.1
#> [1,] 4.397926 4.813876
#> [2,] 4.171889 3.537025
#> [3,] 3.951152 3.836558
#> [4,] 4.096774 4.067378
#> [5,] 4.960829 4.811875
#> [6,] 4.106682 3.869246
#> [7,] 4.654839 4.699800
#> [8,] 4.570046 4.299533
#> [9,] 4.024424 4.471648
#> [10,] 4.004608 3.673783
#> [11,] 4.282258 3.733823
#> [12,] 3.926728 4.299533
#> [13,] 4.019355 4.254837
#> [14,] 4.270276 4.366911
#> [15,] 4.017742 3.742495
#> [16,] 4.198157 3.837892
#> CTCGGAGTCAACCAAC-400.2.1 CTCGTACAGCGACGTA-400.2.1
#> [1,] 4.813053 4.707135
#> [2,] 4.293142 3.962726
#> [3,] 4.366150 3.809372
#> [4,] 4.125000 4.050053
#> [5,] 4.664823 4.990415
#> [6,] 4.536504 3.905218
#> [7,] 4.299779 4.037274
#> [8,] 4.641593 4.620873
#> [9,] 4.276549 4.405751
#> [10,] 4.195796 4.095847
#> [11,] 4.335177 3.773163
#> [12,] 4.009956 4.176784
#> [13,] 4.626106 4.543131
#> [14,] 4.638274 4.080937
#> [15,] 4.419248 4.027689
#> [16,] 4.672566 4.604899
#> CTCGTCAGTATAGGTA-400.2.1 CTCGTCATCATGTCCC-400.2.1
#> [1,] 4.438908 4.730324
#> [2,] 3.823891 4.252315
#> [3,] 4.038225 4.244213
#> [4,] 4.296928 3.965278
#> [5,] 4.780887 4.547454
#> [6,] 3.952901 4.423611
#> [7,] 4.718089 4.251157
#> [8,] 4.275085 4.699074
#> [9,] 4.294881 4.504630
#> [10,] 3.823891 4.434028
#> [11,] 4.458020 4.159722
#> [12,] 4.144027 4.318287
#> [13,] 4.121502 4.282407
#> [14,] 3.997270 4.327546
#> [15,] 3.940614 4.019676
#> [16,] 4.071672 4.395833
#> CTCTACGCATGTAAGA-400.2.1 CTCTGGTCACCGTTGG-400.2.1
#> [1,] 4.466094 4.420567
#> [2,] 3.581374 4.039716
#> [3,] 3.919078 4.007801
#> [4,] 4.167722 4.183688
#> [5,] 4.760850 5.155319
#> [6,] 3.861664 3.862411
#> [7,] 4.741863 4.945390
#> [8,] 4.212477 4.434043
#> [9,] 4.243671 4.087234
#> [10,] 3.644665 3.934752
#> [11,] 3.848553 4.173050
#> [12,] 4.256781 3.670922
#> [13,] 4.280741 4.290780
#> [14,] 4.372966 4.402128
#> [15,] 4.292948 3.652482
#> [16,] 4.156420 4.046809
#> CTCTGGTGTTCAGGCC-400.2.1 CTCTGGTGTTCGCTAA-400.2.1
#> [1,] 4.414712 3.863859
#> [2,] 3.664179 4.353575
#> [3,] 4.182836 4.555338
#> [4,] 4.078358 4.302644
#> [5,] 4.809168 4.466210
#> [6,] 3.800640 4.071499
#> [7,] 4.846482 4.164545
#> [8,] 4.372068 4.714985
#> [9,] 4.158316 4.555338
#> [10,] 3.836354 4.078355
#> [11,] 4.034115 4.422135
#> [12,] 4.326226 4.464251
#> [13,] 4.299041 4.266405
#> [14,] 4.281983 3.812929
#> [15,] 4.402452 3.805093
#> [16,] 4.306503 4.602351
#> CTGAAACTCACCCTCA-400.2.1 CTGATAGTCTGTGCAA-400.2.1
#> [1,] 4.393707 4.692715
#> [2,] 4.285495 4.641060
#> [3,] 4.380660 3.958940
#> [4,] 4.191097 4.092715
#> [5,] 4.316961 4.788079
#> [6,] 3.877206 4.405298
#> [7,] 4.228703 4.332450
#> [8,] 4.413661 4.919205
#> [9,] 4.188795 4.605298
#> [10,] 4.168074 4.298013
#> [11,] 4.174981 4.701987
#> [12,] 4.789716 4.414570
#> [13,] 4.621642 5.107285
#> [14,] 4.124328 4.313907
#> [15,] 4.313124 4.193377
#> [16,] 4.627015 5.030464
#> CTGATCCCAAGGTTTC-400.2.1 CTGCCTAGTAGAAAGG-400.2.1
#> [1,] 4.311321 4.380629
#> [2,] 4.050798 4.197409
#> [3,] 4.274311 4.167798
#> [4,] 4.086357 3.834053
#> [5,] 4.481858 4.779149
#> [6,] 4.137881 3.969772
#> [7,] 4.517417 4.394818
#> [8,] 4.656749 4.599013
#> [9,] 4.306967 4.230105
#> [10,] 4.261248 3.889574
#> [11,] 3.985486 4.311536
#> [12,] 4.195210 4.005552
#> [13,] 4.544993 4.574337
#> [14,] 4.177068 4.033930
#> [15,] 3.894775 4.007403
#> [16,] 4.300435 4.895743
#> CTGCCTAGTATCTGCA-400.2.1 CTGCGGATCGTGGTCG-400.2.1
#> [1,] 4.246661 4.273752
#> [2,] 4.275552 4.198873
#> [3,] 4.188335 4.071659
#> [4,] 4.239575 3.988728
#> [5,] 5.077678 4.689211
#> [6,] 4.004088 3.867955
#> [7,] 4.745707 4.699678
#> [8,] 4.417280 4.690016
#> [9,] 4.301990 4.411433
#> [10,] 4.073317 3.942834
#> [11,] 4.292450 4.346216
#> [12,] 4.060780 4.108696
#> [13,] 4.232216 3.935588
#> [14,] 4.590352 4.754428
#> [15,] 3.954484 3.815620
#> [16,] 4.336877 4.154589
#> CTGCTGTAGCTAGTGG-400.2.1 CTGCTGTCATGGTCAT-400.2.1
#> [1,] 4.342373 4.779661
#> [2,] 4.672316 3.873729
#> [3,] 4.166102 4.301695
#> [4,] 4.289266 4.393220
#> [5,] 4.639548 4.724576
#> [6,] 4.654237 4.404237
#> [7,] 3.889266 4.593220
#> [8,] 4.976271 4.263559
#> [9,] 4.861017 4.233051
#> [10,] 4.449718 4.028814
#> [11,] 4.099435 4.283051
#> [12,] 4.709605 4.142373
#> [13,] 4.497175 3.996610
#> [14,] 4.470056 4.288983
#> [15,] 3.831638 4.148305
#> [16,] 4.590960 4.345763
#> CTGCTGTGTCACAAGG-400.2.1 CTGGTCTAGCCACTAT-400.2.1
#> [1,] 4.240201 4.184066
#> [2,] 4.412060 3.824176
#> [3,] 3.886432 4.015568
#> [4,] 4.175879 4.130037
#> [5,] 4.392965 4.985348
#> [6,] 4.724623 4.020147
#> [7,] 4.841206 4.751832
#> [8,] 4.918593 4.486264
#> [9,] 4.470352 3.529304
#> [10,] 4.580905 3.986264
#> [11,] 4.316583 4.217949
#> [12,] 4.830151 4.023810
#> [13,] 4.379899 4.153846
#> [14,] 4.321608 4.278388
#> [15,] 4.261307 4.058608
#> [16,] 4.518593 4.204212
#> CTGGTCTAGCTAGCCC-400.2.1 CTGGTCTCATGCCCGA-400.2.1
#> [1,] 4.480057 4.478287
#> [2,] 4.325499 4.275229
#> [3,] 4.631054 4.312538
#> [4,] 4.146724 3.844648
#> [5,] 5.279915 4.818960
#> [6,] 4.702991 4.295413
#> [7,] 4.490741 4.293578
#> [8,] 5.138177 4.653211
#> [9,] 4.479345 4.083180
#> [10,] 4.146011 3.931498
#> [11,] 4.438034 4.212232
#> [12,] 4.500000 4.414067
#> [13,] 4.015670 4.379817
#> [14,] 4.072650 4.229358
#> [15,] 4.081197 4.428135
#> [16,] 4.957265 4.359633
#> CTGGTCTCATTGCGGC-400.2.1 CTGTGCTTCTCCAACC-400.2.1
#> [1,] 4.311499 4.298222
#> [2,] 4.449782 4.238030
#> [3,] 4.208879 3.856361
#> [4,] 4.216885 4.180575
#> [5,] 4.443959 4.322845
#> [6,] 4.119360 4.619699
#> [7,] 4.606987 4.616963
#> [8,] 4.724163 5.069767
#> [9,] 4.482533 4.652531
#> [10,] 4.409025 4.369357
#> [11,] 4.619360 4.165527
#> [12,] 4.762737 4.593707
#> [13,] 4.403930 4.584131
#> [14,] 4.309316 4.311902
#> [15,] 4.313683 4.380301
#> [16,] 4.526201 4.766074
#> CTGTTTAGTCCGTCAG-400.2.1 CTGTTTATCCCATTTA-400.2.1
#> [1,] 4.403071 4.292929
#> [2,] 4.288548 4.313763
#> [3,] 4.428023 4.173611
#> [4,] 4.136276 3.999369
#> [5,] 4.480486 4.712121
#> [6,] 4.387716 4.042929
#> [7,] 4.011516 4.390783
#> [8,] 4.456814 4.910985
#> [9,] 4.261036 4.414773
#> [10,] 4.326935 4.253788
#> [11,] 4.133717 4.154040
#> [12,] 4.319258 4.320707
#> [13,] 4.353167 4.445707
#> [14,] 4.370441 4.109848
#> [15,] 4.119002 4.005682
#> [16,] 4.739603 4.267045
#> CTTACCGAGCCAGGAT-400.2.1 CTTACCGCAGACGCTC-400.2.1
#> [1,] 4.762788 4.460157
#> [2,] 3.682968 3.938272
#> [3,] 4.145587 4.252525
#> [4,] 4.103429 4.123457
#> [5,] 5.179314 4.534231
#> [6,] 3.749297 3.989899
#> [7,] 4.954469 4.324355
#> [8,] 4.234963 4.575758
#> [9,] 4.115795 4.306397
#> [10,] 3.633502 4.112233
#> [11,] 4.039910 4.107744
#> [12,] 4.061832 4.270483
#> [13,] 4.187746 4.386083
#> [14,] 4.088814 4.081930
#> [15,] 3.618887 4.000000
#> [16,] 4.005059 4.332211
#> CTTCTCTCAGAGCCAA-400.2.1 CTTCTCTCATAACCTG-400.2.1
#> [1,] 4.712670 4.317116
#> [2,] 3.855769 4.327541
#> [3,] 4.309389 4.298871
#> [4,] 4.184672 4.192007
#> [5,] 4.516120 4.780191
#> [6,] 4.209842 4.410947
#> [7,] 4.373586 4.048653
#> [8,] 4.434672 5.114683
#> [9,] 4.360294 4.839270
#> [10,] 3.979921 4.126846
#> [11,] 4.374152 4.351868
#> [12,] 4.265271 4.355343
#> [13,] 4.321550 4.806255
#> [14,] 3.988971 4.341442
#> [15,] 3.907523 3.822763
#> [16,] 4.300057 4.578627
#> GAAACTCCAGGGCATA-400.2.1 GAAACTCGTGGCTCCA-400.2.1
#> [1,] 4.689873 4.388745
#> [2,] 4.180832 4.133333
#> [3,] 4.141953 4.600000
#> [4,] 4.468354 4.134199
#> [5,] 4.202532 4.610390
#> [6,] 4.518987 4.101299
#> [7,] 4.307414 4.179221
#> [8,] 5.349910 4.954978
#> [9,] 4.875226 5.055411
#> [10,] 4.266727 4.486580
#> [11,] 4.334539 3.834632
#> [12,] 4.524412 4.279654
#> [13,] 4.583183 4.393939
#> [14,] 4.476492 4.267532
#> [15,] 4.441230 4.235498
#> [16,] 4.390597 4.555844
#> GAAATGAAGACGCAAC-400.2.1 GAAATGACAATCTGCA-400.2.1
#> [1,] 4.039201 4.310748
#> [2,] 4.259800 3.584696
#> [3,] 4.149885 3.867991
#> [4,] 4.062260 3.954439
#> [5,] 4.657955 5.175234
#> [6,] 4.087625 3.869159
#> [7,] 4.103766 5.259346
#> [8,] 4.695619 4.153621
#> [9,] 4.633359 4.395444
#> [10,] 4.652575 3.598715
#> [11,] 4.224443 4.206776
#> [12,] 4.378939 4.056659
#> [13,] 4.468101 4.419393
#> [14,] 4.129131 4.500000
#> [15,] 4.326672 3.619743
#> [16,] 4.750961 3.884346
#> GAACATCAGGCCCTCA-400.2.1 GAACATCCAATCACAC-400.2.1
#> [1,] 4.584470 4.404055
#> [2,] 4.285414 4.287473
#> [3,] 4.527807 4.138306
#> [4,] 4.009444 4.117306
#> [5,] 4.727177 4.514120
#> [6,] 4.534103 4.380159
#> [7,] 4.149003 4.414193
#> [8,] 4.922350 4.454743
#> [9,] 4.676810 4.131064
#> [10,] 4.416579 4.274439
#> [11,] 4.364113 4.320782
#> [12,] 4.563484 4.467053
#> [13,] 4.770199 4.189718
#> [14,] 4.231899 4.325851
#> [15,] 4.049318 4.111513
#> [16,] 4.481637 4.553222
#> GAACATCGTCCGACGT-400.2.1 GAACGGACACATGACT-400.2.1
#> [1,] 4.014376 3.997335
#> [2,] 4.351303 4.324627
#> [3,] 4.477987 4.213753
#> [4,] 3.958670 3.850746
#> [5,] 5.091644 3.883262
#> [6,] 4.012579 3.917377
#> [7,] 4.314465 4.001599
#> [8,] 4.623540 5.074094
#> [9,] 4.301887 4.529851
#> [10,] 4.317161 3.858742
#> [11,] 4.112309 4.290512
#> [12,] 4.089847 4.673774
#> [13,] 4.045822 4.527186
#> [14,] 4.381851 3.816631
#> [15,] 4.542677 4.457889
#> [16,] 4.584007 4.545309
#> GAAGCAGAGTGAACAT-400.2.1 GAAGCAGGTGACCAAG-400.2.1
#> [1,] 4.221750 4.818700
#> [2,] 4.258202 3.570696
#> [3,] 4.155529 3.770239
#> [4,] 4.362090 4.230901
#> [5,] 4.603888 5.142531
#> [6,] 4.465978 3.906499
#> [7,] 4.252734 4.786203
#> [8,] 4.665249 4.404219
#> [9,] 4.585662 4.025086
#> [10,] 4.343864 3.578677
#> [11,] 4.339611 4.216078
#> [12,] 4.382746 3.997149
#> [13,] 4.368773 4.300456
#> [14,] 3.972053 4.062144
#> [15,] 3.913123 4.097491
#> [16,] 4.376671 4.278791
#> GAATAAGCAACACGCC-400.2.1 GAATGAAAGTGTCCCG-400.2.1
#> [1,] 4.580247 4.678030
#> [2,] 3.426487 4.308081
#> [3,] 3.689113 4.108586
#> [4,] 4.006734 4.162879
#> [5,] 5.164983 4.708333
#> [6,] 3.846240 4.303030
#> [7,] 4.984287 4.368687
#> [8,] 4.187430 5.075758
#> [9,] 4.182941 4.630051
#> [10,] 3.765432 4.157828
#> [11,] 4.396184 4.393939
#> [12,] 4.041526 4.723485
#> [13,] 4.161616 5.034091
#> [14,] 4.350168 4.335859
#> [15,] 3.665544 4.126263
#> [16,] 3.827160 4.806818
#> GAATGAATCTGCGGCA-400.2.1 GACAGAGCAGATTGCT-400.2.1
#> [1,] 4.231169 4.558961
#> [2,] 4.258874 3.517655
#> [3,] 4.060606 3.746835
#> [4,] 4.220779 4.016656
#> [5,] 4.412121 5.510993
#> [6,] 4.062338 3.930713
#> [7,] 4.242424 5.370420
#> [8,] 4.595671 4.045303
#> [9,] 4.310823 4.142572
#> [10,] 4.079654 3.833444
#> [11,] 4.093506 4.003331
#> [12,] 3.929870 4.084610
#> [13,] 4.603463 4.250500
#> [14,] 4.335065 4.267155
#> [15,] 3.936797 3.828781
#> [16,] 4.670996 4.267821
#> GACGCGTCACGCATCG-400.2.1 GACGTGCGTCCGCTGA-400.2.1
#> [1,] 4.412311 4.232576
#> [2,] 4.405343 4.119812
#> [3,] 4.214866 4.053250
#> [4,] 3.887340 3.861394
#> [5,] 4.901278 4.589663
#> [6,] 4.315912 4.048551
#> [7,] 4.365854 4.437745
#> [8,] 4.874564 4.547377
#> [9,] 4.686411 4.057165
#> [10,] 3.975610 4.308536
#> [11,] 4.233449 3.918559
#> [12,] 4.505226 4.176977
#> [13,] 4.427410 4.150352
#> [14,] 3.924506 4.223179
#> [15,] 4.092915 4.176194
#> [16,] 4.432056 4.272514
#> GACTAACCAATGTTGC-400.2.1 GACTAACGTATAGGGC-400.2.1
#> [1,] 4.108367 4.758357
#> [2,] 4.356005 3.903534
#> [3,] 4.231579 4.001910
#> [4,] 4.302429 4.498567
#> [5,] 4.919838 5.005731
#> [6,] 4.235628 3.959885
#> [7,] 4.811471 4.373448
#> [8,] 4.152767 4.552053
#> [9,] 4.113090 4.252149
#> [10,] 4.234278 4.016237
#> [11,] 4.246559 3.871060
#> [12,] 4.209717 4.113658
#> [13,] 4.363428 4.678128
#> [14,] 4.617544 4.060172
#> [15,] 3.971660 4.093601
#> [16,] 4.277193 4.317096
#> GACTACACAGATCCAT-400.2.1 GAGGTGACACAACTGT-400.2.1
#> [1,] 4.508015 4.339839
#> [2,] 4.266338 4.352468
#> [3,] 4.118372 3.958668
#> [4,] 4.124538 4.149254
#> [5,] 4.604192 4.936854
#> [6,] 4.320592 4.174512
#> [7,] 4.427867 4.667049
#> [8,] 4.728730 4.490241
#> [9,] 4.426634 4.247991
#> [10,] 4.601726 4.043628
#> [11,] 4.679408 4.431688
#> [12,] 4.409371 4.258324
#> [13,] 4.135635 4.504018
#> [14,] 3.928483 4.337543
#> [15,] 3.983970 3.831228
#> [16,] 4.325524 4.540758
#> GAGTCCGTCTGCTGTC-400.2.1 GATCAGTAGGCGATAC-400.2.1
#> [1,] 4.580899 4.752460
#> [2,] 3.974157 3.799394
#> [3,] 4.004494 4.211961
#> [4,] 4.207865 4.185466
#> [5,] 4.687640 4.940954
#> [6,] 5.049438 4.222559
#> [7,] 3.989888 4.940197
#> [8,] 5.122472 4.231643
#> [9,] 4.437079 4.068887
#> [10,] 4.217978 3.758516
#> [11,] 4.035955 4.366389
#> [12,] 4.514607 4.252082
#> [13,] 4.641573 4.185466
#> [14,] 4.556180 4.274792
#> [15,] 4.107865 3.866011
#> [16,] 5.385393 3.707040
#> GATCAGTTCCAGGGCT-400.2.1 GATCGCGAGTACGCGA-400.2.1
#> [1,] 4.540919 4.720974
#> [2,] 4.599776 4.384831
#> [3,] 4.122197 4.463483
#> [4,] 4.154148 4.455056
#> [5,] 4.605381 4.385768
#> [6,] 4.463565 4.375468
#> [7,] 4.227578 4.386704
#> [8,] 5.018498 4.779026
#> [9,] 4.716368 4.592697
#> [10,] 4.305493 4.323034
#> [11,] 4.239350 4.426966
#> [12,] 4.456839 4.428839
#> [13,] 4.544843 4.517790
#> [14,] 4.127242 4.316479
#> [15,] 4.166480 4.279963
#> [16,] 4.802130 4.616105
#> GATCGTACAAGCCGTC-400.2.1 GATCTAGGTTGTTTGG-400.2.1
#> [1,] 4.353488 4.351425
#> [2,] 4.059136 4.282225
#> [3,] 4.403322 4.245590
#> [4,] 4.123588 4.576662
#> [5,] 4.871096 4.736771
#> [6,] 4.690365 3.959294
#> [7,] 4.440532 3.989145
#> [8,] 4.788040 5.128901
#> [9,] 4.579402 4.773406
#> [10,] 4.338870 4.200814
#> [11,] 4.373422 4.352782
#> [12,] 4.358140 4.639077
#> [13,] 4.223920 4.685210
#> [14,] 4.116944 4.075984
#> [15,] 4.269103 3.943012
#> [16,] 4.228571 4.681140
#> GATGAAAAGGGATGGG-400.2.1 GATGAAAAGTGTTAGA-400.2.1
#> [1,] 4.657210 4.529175
#> [2,] 4.105201 4.783702
#> [3,] 4.196217 3.736419
#> [4,] 4.248227 4.171026
#> [5,] 4.358156 4.767606
#> [6,] 4.578014 4.655936
#> [7,] 4.003546 4.369215
#> [8,] 4.905437 5.336016
#> [9,] 4.484634 4.328974
#> [10,] 3.861702 4.614688
#> [11,] 4.559102 4.231388
#> [12,] 4.382979 4.576459
#> [13,] 4.606383 4.687123
#> [14,] 4.533097 4.306841
#> [15,] 4.042553 3.791751
#> [16,] 4.299054 4.016097
#> GATGAGGAGCTAGTTC-400.2.1 GATGAGGCACGGCTAC-400.2.1
#> [1,] 4.490467 4.816412
#> [2,] 3.575279 3.759388
#> [3,] 4.158448 3.961057
#> [4,] 4.067719 3.801808
#> [5,] 4.932939 5.426982
#> [6,] 4.006575 4.043811
#> [7,] 4.832347 4.484701
#> [8,] 4.493754 4.176634
#> [9,] 4.350427 4.235049
#> [10,] 3.817883 3.683588
#> [11,] 3.900066 4.064673
#> [12,] 4.198554 4.077886
#> [13,] 4.264957 4.158554
#> [14,] 4.420118 4.294159
#> [15,] 4.300460 3.951321
#> [16,] 4.339908 4.563282
#> GATGCTAGTTGTACAC-400.2.1 GCAAACTAGAAACCTA-400.2.1
#> [1,] 5.854188 4.578729
#> [2,] 3.543950 4.197974
#> [3,] 3.788004 4.363720
#> [4,] 4.847983 4.182781
#> [5,] 5.211996 4.937385
#> [6,] 3.464323 3.935543
#> [7,] 3.750776 4.473297
#> [8,] 4.785936 4.515654
#> [9,] 3.512927 3.896409
#> [10,] 3.559462 4.087937
#> [11,] 3.910031 4.412983
#> [12,] 3.751810 4.055709
#> [13,] 4.028956 4.105893
#> [14,] 3.665977 4.446593
#> [15,] 4.509824 4.081952
#> [16,] 4.963806 4.414825
#> GCAAACTAGATGCCAG-400.2.1 GCAATCAAGATCACGG-400.2.1
#> [1,] 4.257062 4.487608
#> [2,] 4.496234 3.858213
#> [3,] 4.166667 3.908934
#> [4,] 4.234463 4.425937
#> [5,] 4.737288 5.049568
#> [6,] 4.430320 3.889914
#> [7,] 4.165725 4.484726
#> [8,] 4.794727 4.459942
#> [9,] 5.022599 4.228818
#> [10,] 4.242938 3.843228
#> [11,] 4.369115 4.292219
#> [12,] 4.551789 4.067435
#> [13,] 4.465160 4.160231
#> [14,] 4.219397 4.234006
#> [15,] 4.137476 4.131988
#> [16,] 4.723164 4.370029
#> GCAATCAAGCTAGCCC-400.2.1 GCAATCATCATGCTCC-400.2.1
#> [1,] 4.343402 4.207645
#> [2,] 4.264706 4.460744
#> [3,] 4.251192 4.102273
#> [4,] 4.202703 4.036157
#> [5,] 4.504769 4.729339
#> [6,] 4.075517 4.826446
#> [7,] 4.034976 4.366736
#> [8,] 5.093800 5.103306
#> [9,] 4.317965 4.697314
#> [10,] 4.350556 4.154959
#> [11,] 3.968998 4.303719
#> [12,] 4.354531 4.260331
#> [13,] 4.403816 4.116736
#> [14,] 4.120827 4.194215
#> [15,] 4.216216 4.144628
#> [16,] 4.338633 4.690083
#> GCACATAAGGGTGTGT-400.2.1 GCACTCTGTCACCTAA-400.2.1
#> [1,] 4.465039 4.379795
#> [2,] 3.974348 4.487212
#> [3,] 4.103848 4.010230
#> [4,] 4.350021 4.223785
#> [5,] 4.884981 4.671355
#> [6,] 4.009930 4.470588
#> [7,] 4.860157 4.482097
#> [8,] 4.486554 4.878517
#> [9,] 4.300372 4.920716
#> [10,] 3.897807 4.148338
#> [11,] 4.242449 4.295396
#> [12,] 4.334299 4.335038
#> [13,] 4.184940 4.419437
#> [14,] 4.449731 4.212276
#> [15,] 4.101365 4.236573
#> [16,] 4.526272 4.420716
#> GCAGTTACAATCTGCA-400.2.1 GCATACATCACATACG-400.2.1
#> [1,] 4.345858 4.780612
#> [2,] 4.426132 4.744898
#> [3,] 4.456020 3.787755
#> [4,] 4.403074 4.555102
#> [5,] 4.729291 4.523469
#> [6,] 4.445773 4.796939
#> [7,] 4.033305 3.962245
#> [8,] 4.791631 4.646939
#> [9,] 4.615713 4.232653
#> [10,] 4.233988 4.956122
#> [11,] 4.228010 4.420408
#> [12,] 4.483348 4.820408
#> [13,] 4.555935 4.721429
#> [14,] 4.285226 4.224490
#> [15,] 4.353544 3.796939
#> [16,] 4.923143 4.363265
#> GCATGCGTCGCCAGCA-400.2.1 GCCAAATAGGCTAGAC-400.2.1
#> [1,] 4.583774 4.587099
#> [2,] 3.378013 3.819267
#> [3,] 3.958260 4.081557
#> [4,] 4.027631 4.220233
#> [5,] 5.316872 5.061097
#> [6,] 3.779541 3.840864
#> [7,] 4.793651 4.904234
#> [8,] 4.241623 4.099460
#> [9,] 4.235744 4.225632
#> [10,] 3.714286 3.737710
#> [11,] 3.825397 4.015345
#> [12,] 3.951205 4.171355
#> [13,] 4.286890 4.384484
#> [14,] 4.400941 4.108269
#> [15,] 4.011758 3.812731
#> [16,] 4.211640 4.031543
#> GCGACCATCAGAGGTG-400.2.1 GCGAGAAAGAATGTTG-400.2.1
#> [1,] 4.306468 4.424829
#> [2,] 3.989055 3.645216
#> [3,] 4.247761 3.821754
#> [4,] 4.513433 4.354214
#> [5,] 4.897512 5.259112
#> [6,] 3.784080 3.523918
#> [7,] 4.697512 4.890091
#> [8,] 4.749254 4.411731
#> [9,] 4.128358 4.129271
#> [10,] 3.955224 3.665718
#> [11,] 3.959204 4.084282
#> [12,] 4.004975 3.893508
#> [13,] 4.061692 3.915148
#> [14,] 4.065672 4.551822
#> [15,] 4.298507 3.545558
#> [16,] 4.112438 3.826879
#> GCGAGAACAGCTGTTA-400.2.1 GCGAGAATCCGTACAA-400.2.1
#> [1,] 4.194779 4.724165
#> [2,] 4.201807 4.229992
#> [3,] 3.897590 4.165501
#> [4,] 4.228916 4.292152
#> [5,] 4.476908 4.730381
#> [6,] 4.032129 4.122766
#> [7,] 4.297189 4.010878
#> [8,] 4.975904 4.611500
#> [9,] 4.486948 4.979021
#> [10,] 4.343373 3.997669
#> [11,] 4.672691 4.141414
#> [12,] 4.650602 4.201243
#> [13,] 4.276104 4.328671
#> [14,] 4.149598 4.372960
#> [15,] 4.135542 3.720280
#> [16,] 4.380522 4.646465
#> GCGCCAACATTAACCG-400.2.1 GCTCCTAAGGATGCGT-400.2.1
#> [1,] 4.932234 4.390285
#> [2,] 3.489011 4.254606
#> [3,] 3.924298 4.476549
#> [4,] 4.487790 4.505863
#> [5,] 4.656288 4.243719
#> [6,] 4.116606 4.453099
#> [7,] 4.585470 4.188442
#> [8,] 4.475580 5.040201
#> [9,] 4.204518 4.522613
#> [10,] 3.702686 4.520938
#> [11,] 4.261294 4.469849
#> [12,] 4.180098 4.427136
#> [13,] 4.331502 4.491625
#> [14,] 4.122711 4.239531
#> [15,] 3.813797 4.411223
#> [16,] 4.135531 4.070352
#> GCTCCTAAGGCTACGA-400.2.1 GCTCCTAGTAAGGGAA-400.2.1
#> [1,] 4.410119 4.177621
#> [2,] 3.752976 4.007825
#> [3,] 4.158929 4.074335
#> [4,] 4.253571 3.881847
#> [5,] 5.152976 5.088419
#> [6,] 3.769048 3.997653
#> [7,] 5.083929 4.988263
#> [8,] 4.320238 4.453834
#> [9,] 4.064881 3.964006
#> [10,] 3.829167 4.163537
#> [11,] 4.004167 3.889671
#> [12,] 4.024405 3.911581
#> [13,] 4.204167 4.383412
#> [14,] 4.342857 4.283255
#> [15,] 3.830357 4.183099
#> [16,] 4.082143 4.383412
#> GCTCCTAGTCGCATAT-400.2.1 GCTCCTATCAGCGACC-400.2.1
#> [1,] 4.089571 4.253199
#> [2,] 4.353374 4.561243
#> [3,] 4.000000 4.217550
#> [4,] 3.997546 3.907678
#> [5,] 4.631902 4.741316
#> [6,] 4.311656 4.683729
#> [7,] 3.862577 4.406764
#> [8,] 4.652761 5.148995
#> [9,] 4.373006 4.493601
#> [10,] 4.465031 3.873857
#> [11,] 4.206135 4.577697
#> [12,] 4.577914 4.355576
#> [13,] 4.359509 4.309872
#> [14,] 3.977914 3.846435
#> [15,] 4.215951 3.854662
#> [16,] 4.564417 4.639854
#> GCTCTGTTCAGCTCTC-400.2.1 GCTCTGTTCTGCGACG-400.2.1
#> [1,] 4.100649 4.528541
#> [2,] 4.034271 4.455603
#> [3,] 4.342713 4.412262
#> [4,] 4.162698 4.394292
#> [5,] 5.093074 4.841438
#> [6,] 3.960678 4.448203
#> [7,] 4.762266 4.024313
#> [8,] 4.215007 4.992600
#> [9,] 4.041126 4.915433
#> [10,] 4.040043 4.214588
#> [11,] 4.304113 4.393235
#> [12,] 4.308442 4.633192
#> [13,] 4.173160 4.607822
#> [14,] 4.230159 4.187104
#> [15,] 4.055556 3.913319
#> [16,] 4.294733 4.601480
#> GCTGCAGAGTACGACG-400.2.1 GCTGCGATCTTACCTA-400.2.1
#> [1,] 4.252674 4.372294
#> [2,] 4.410428 4.295455
#> [3,] 3.883690 4.107143
#> [4,] 4.288770 4.202381
#> [5,] 4.520053 4.487013
#> [6,] 3.883690 4.258658
#> [7,] 4.064171 4.136364
#> [8,] 4.898396 5.109307
#> [9,] 4.790107 4.555195
#> [10,] 4.601604 4.275974
#> [11,] 4.057487 4.518398
#> [12,] 4.422460 4.550866
#> [13,] 4.399733 4.616883
#> [14,] 4.300802 3.948052
#> [15,] 4.677807 4.166667
#> [16,] 4.649733 4.359307
#> GCTGGGTCATCGGGTC-400.2.1 GCTGGGTGTTAGGGTG-400.2.1
#> [1,] 4.486755 4.315922
#> [2,] 4.094923 3.960824
#> [3,] 4.377483 4.147162
#> [4,] 4.025386 4.308388
#> [5,] 4.727373 4.943245
#> [6,] 3.650110 3.992466
#> [7,] 3.922737 4.871421
#> [8,] 5.229581 4.235058
#> [9,] 4.114790 4.042190
#> [10,] 3.722958 3.839779
#> [11,] 4.240618 4.188850
#> [12,] 4.174393 3.757911
#> [13,] 4.644592 4.086891
#> [14,] 3.986755 4.419387
#> [15,] 4.056291 3.936213
#> [16,] 4.400662 4.257157
#> GCTGGGTTCTGATACG-400.2.1 GGAAAGCGTCACTTCC-400.2.1
#> [1,] 4.619580 4.340580
#> [2,] 4.009091 3.847101
#> [3,] 4.500699 4.084058
#> [4,] 4.017483 3.923188
#> [5,] 4.641958 4.946377
#> [6,] 4.927972 4.056522
#> [7,] 4.137762 4.189130
#> [8,] 4.686713 4.776087
#> [9,] 4.636364 4.123913
#> [10,] 4.400000 3.798551
#> [11,] 4.567832 3.920290
#> [12,] 4.673427 4.428261
#> [13,] 4.126573 4.715217
#> [14,] 4.584615 3.886232
#> [15,] 4.602797 4.234058
#> [16,] 4.308392 4.041304
#> GGAAAGCGTCGCATCG-400.2.1 GGAACTTAGTGCAAGC-400.2.1
#> [1,] 4.003093 4.261653
#> [2,] 3.776289 4.758235
#> [3,] 3.994330 4.300186
#> [4,] 4.089691 4.065258
#> [5,] 5.253608 4.441889
#> [6,] 4.054124 3.968303
#> [7,] 5.059794 4.063393
#> [8,] 4.159794 5.139217
#> [9,] 4.072165 4.374145
#> [10,] 4.131959 4.339341
#> [11,] 4.103093 4.497203
#> [12,] 4.043814 4.330019
#> [13,] 4.193299 4.586700
#> [14,] 4.360309 4.501554
#> [15,] 3.991753 3.904910
#> [16,] 4.088660 4.402735
#> GGAACTTGTTCAGGCC-400.2.1 GGAACTTTCGACCAGC-400.2.1
#> [1,] 4.789179 4.625922
#> [2,] 3.199627 3.481560
#> [3,] 3.688433 3.876712
#> [4,] 4.418843 4.355111
#> [5,] 5.152985 5.159115
#> [6,] 3.775187 3.709168
#> [7,] 4.644590 4.769231
#> [8,] 4.493470 4.293994
#> [9,] 4.408582 4.432034
#> [10,] 3.740672 3.861960
#> [11,] 3.833022 3.571128
#> [12,] 3.874067 4.074816
#> [13,] 4.270522 4.707060
#> [14,] 4.189366 4.295047
#> [15,] 4.028918 3.562698
#> [16,] 3.942164 4.189673
#> GGAATAACATTGCGGC-400.2.1 GGACAAGAGTAGTGCG-400.2.1
#> [1,] 4.474738 4.529745
#> [2,] 3.982841 4.259915
#> [3,] 3.925643 4.342776
#> [4,] 4.505243 4.080737
#> [5,] 4.967588 4.441218
#> [6,] 3.808389 4.469547
#> [7,] 4.644423 4.421388
#> [8,] 4.747378 4.944051
#> [9,] 4.241182 4.655099
#> [10,] 4.049571 4.599858
#> [11,] 3.811249 4.341360
#> [12,] 4.091516 4.739377
#> [13,] 4.530029 4.233003
#> [14,] 4.158246 4.112606
#> [15,] 4.107722 4.322238
#> [16,] 4.535748 4.677762
#> GGACAAGTCTTCATGT-400.2.1 GGACAGAAGAGGTAGA-400.2.1
#> [1,] 4.636189 4.265842
#> [2,] 3.726343 3.902970
#> [3,] 3.570972 4.042574
#> [4,] 3.991049 4.095050
#> [5,] 5.529412 4.904950
#> [6,] 3.803708 4.128218
#> [7,] 4.932225 4.855941
#> [8,] 3.959719 4.253465
#> [9,] 4.126598 4.174257
#> [10,] 3.585678 3.978713
#> [11,] 4.007033 4.305446
#> [12,] 3.741049 4.073762
#> [13,] 4.334399 4.437624
#> [14,] 4.385550 4.341089
#> [15,] 3.842072 3.851980
#> [16,] 4.373402 4.154950
#> GGACAGAAGTGGACGT-400.2.1 GGACATTTCTCGGACG-400.2.1
#> [1,] 4.020122 4.500958
#> [2,] 4.221347 3.585942
#> [3,] 4.062992 3.764856
#> [4,] 3.907262 4.604473
#> [5,] 5.006124 4.812141
#> [6,] 3.831146 3.658147
#> [7,] 4.693788 5.106709
#> [8,] 4.987752 4.096486
#> [9,] 4.314086 3.943131
#> [10,] 4.072616 3.715655
#> [11,] 4.468066 3.840895
#> [12,] 3.945757 3.845367
#> [13,] 3.782152 4.171885
#> [14,] 4.739283 4.279233
#> [15,] 3.772528 3.669649
#> [16,] 4.109361 3.969968
#> GGACGTCAGACATAAC-400.2.1 GGAGCAATCAGCTTAG-400.2.1
#> [1,] 4.911173 4.851360
#> [2,] 3.899441 4.465257
#> [3,] 3.922905 3.998187
#> [4,] 4.431285 4.394562
#> [5,] 4.970391 4.566767
#> [6,] 4.174302 4.325076
#> [7,] 4.394413 4.319033
#> [8,] 4.668156 4.803625
#> [9,] 4.149162 4.426586
#> [10,] 3.962570 4.693656
#> [11,] 3.908939 4.717221
#> [12,] 4.327374 4.203021
#> [13,] 4.359218 4.541390
#> [14,] 4.182123 4.093051
#> [15,] 4.023464 3.842900
#> [16,] 3.906145 4.081571
#> GGATTACAGTAGATGT-400.2.1 GGATTACGTATGAATG-400.2.1
#> [1,] 4.554455 4.528398
#> [2,] 4.134213 4.274848
#> [3,] 3.872387 4.033469
#> [4,] 3.833883 4.268763
#> [5,] 5.355336 4.498986
#> [6,] 3.924092 4.584178
#> [7,] 4.974697 4.360041
#> [8,] 4.401540 4.644016
#> [9,] 4.114411 4.720081
#> [10,] 3.888889 4.295132
#> [11,] 4.350935 4.309331
#> [12,] 4.029703 4.461460
#> [13,] 4.152915 4.601420
#> [14,] 4.479648 4.270791
#> [15,] 4.135314 4.215010
#> [16,] 4.334433 4.773834
#> GGCAATTGTACGCTGC-400.2.1 GGCCGATTCAGAGACG-400.2.1
#> [1,] 4.169982 4.283681
#> [2,] 4.357143 4.021822
#> [3,] 4.367993 4.169829
#> [4,] 4.284810 3.962998
#> [5,] 4.809222 4.702087
#> [6,] 3.800181 4.240987
#> [7,] 4.573237 4.533207
#> [8,] 4.848101 4.666034
#> [9,] 4.391501 4.381404
#> [10,] 4.363472 4.172676
#> [11,] 4.359855 4.157495
#> [12,] 4.085895 4.760911
#> [13,] 4.162749 4.661290
#> [14,] 4.367993 3.980076
#> [15,] 4.063291 4.203036
#> [16,] 4.300181 4.434535
#> GGCCGATTCGAATCCA-400.2.1 GGCGACTAGAACAACT-400.2.1
#> [1,] 4.287582 4.300474
#> [2,] 4.265173 4.424881
#> [3,] 4.190476 4.127043
#> [4,] 4.067227 4.110174
#> [5,] 4.449113 4.404850
#> [6,] 4.170868 4.390617
#> [7,] 4.244631 4.303110
#> [8,] 4.674136 4.700580
#> [9,] 4.530345 4.367949
#> [10,] 4.393091 4.476015
#> [11,] 4.434174 4.066948
#> [12,] 4.203548 4.472852
#> [13,] 4.433240 4.191355
#> [14,] 4.191410 4.081181
#> [15,] 4.162465 4.366895
#> [16,] 4.383754 4.400105
#> GGCGACTTCTGAAAGA-400.2.1 GGCTCGATCTCAACTT-400.2.1
#> [1,] 4.532030 4.167282
#> [2,] 4.484828 4.116851
#> [3,] 4.117330 4.012300
#> [4,] 3.989211 4.045510
#> [5,] 4.674309 4.441574
#> [6,] 4.148348 4.388684
#> [7,] 4.225219 4.252153
#> [8,] 5.047202 4.629766
#> [9,] 4.772084 4.996310
#> [10,] 4.255563 3.956950
#> [11,] 4.480108 4.544895
#> [12,] 4.357384 4.785978
#> [13,] 4.424815 4.243542
#> [14,] 4.285907 4.204182
#> [15,] 4.271072 4.094711
#> [16,] 4.362778 4.611316
#> GGCTGGTCATCGATGT-400.2.1 GGGAATGCAGACAAGC-400.2.1
#> [1,] 4.304462 4.539787
#> [2,] 4.208224 3.731747
#> [3,] 3.671916 3.852338
#> [4,] 4.073491 4.178835
#> [5,] 4.774278 5.150943
#> [6,] 3.888014 3.496308
#> [7,] 4.245844 4.438064
#> [8,] 4.880140 4.491386
#> [9,] 4.256343 4.158326
#> [10,] 3.815398 3.700574
#> [11,] 4.181977 3.603774
#> [12,] 4.280840 3.986054
#> [13,] 4.154856 4.442166
#> [14,] 4.723535 4.187859
#> [15,] 3.668416 3.951600
#> [16,] 4.553806 4.092699
#> GGGAGATGTCCAGTGC-400.2.1 GGGCATCAGGTGATAT-400.2.1
#> [1,] 4.207748 4.520422
#> [2,] 4.241687 4.044796
#> [3,] 4.446692 4.032279
#> [4,] 4.125471 4.312253
#> [5,] 4.762084 4.724638
#> [6,] 4.244429 4.138999
#> [7,] 4.601646 4.262187
#> [8,] 4.654782 4.571146
#> [9,] 4.220432 4.445323
#> [10,] 4.278711 4.048748
#> [11,] 4.450120 4.111989
#> [12,] 4.438464 4.379447
#> [13,] 4.151526 4.413702
#> [14,] 4.350017 3.891963
#> [15,] 4.077820 4.265481
#> [16,] 4.467261 4.301713
#> GGGTCTGCACATGACT-400.2.1 GGGTCTGTCTGGCGAC-400.2.1
#> [1,] 4.420375 4.295067
#> [2,] 4.221311 4.247534
#> [3,] 4.199063 4.038565
#> [4,] 3.940281 4.308520
#> [5,] 4.799766 4.483408
#> [6,] 4.507026 4.193722
#> [7,] 4.096019 4.317489
#> [8,] 4.709602 4.576682
#> [9,] 4.505855 4.174888
#> [10,] 4.120609 4.309417
#> [11,] 3.996487 4.361435
#> [12,] 4.271663 4.466368
#> [13,] 4.494145 4.557848
#> [14,] 3.975410 4.019731
#> [15,] 4.070258 4.266368
#> [16,] 4.574941 4.795516
#> GGGTTGCAGCGATTCT-400.2.1 GGTATTGAGATCCGAG-400.2.1
#> [1,] 4.460714 4.072340
#> [2,] 3.909821 4.455745
#> [3,] 4.113393 4.557447
#> [4,] 4.313393 4.119574
#> [5,] 4.958036 4.517872
#> [6,] 4.040179 4.125106
#> [7,] 5.057143 4.702553
#> [8,] 4.553571 4.734894
#> [9,] 4.039286 4.573617
#> [10,] 4.105357 4.071489
#> [11,] 4.357143 4.464255
#> [12,] 3.900893 4.240000
#> [13,] 4.133036 4.175745
#> [14,] 4.109821 4.413617
#> [15,] 3.561607 4.128936
#> [16,] 3.921429 4.156596
#> GGTATTGCAGTTTACG-400.2.1 GGTATTGGTCTTGATG-400.2.1
#> [1,] 4.364421 4.428218
#> [2,] 4.050086 4.188119
#> [3,] 3.970063 4.227723
#> [4,] 4.400691 3.903465
#> [5,] 5.075993 4.294554
#> [6,] 4.075993 4.415842
#> [7,] 5.013241 4.327970
#> [8,] 4.226252 4.823020
#> [9,] 3.867012 4.503713
#> [10,] 3.953944 3.805693
#> [11,] 4.131261 4.237624
#> [12,] 3.938975 4.599010
#> [13,] 4.183074 4.569307
#> [14,] 4.371906 4.163366
#> [15,] 3.831894 4.324257
#> [16,] 4.018998 4.694307
#> GGTGAAGCACGGACAA-400.2.1 GGTGCGTAGCTTCGCG-400.2.1
#> [1,] 4.338956 4.689655
#> [2,] 4.307631 3.889417
#> [3,] 4.151807 4.097503
#> [4,] 4.189558 4.241379
#> [5,] 4.569478 4.945303
#> [6,] 4.146185 4.102259
#> [7,] 4.187149 4.581451
#> [8,] 4.511647 4.388823
#> [9,] 4.454618 3.957194
#> [10,] 4.319679 3.900119
#> [11,] 4.307631 4.116528
#> [12,] 4.808835 3.771700
#> [13,] 4.640161 4.134364
#> [14,] 3.936546 4.068966
#> [15,] 4.468273 3.989298
#> [16,] 4.451406 4.580262
#> GTAACGTCATTCTCAT-400.2.1 GTAACTGCACAGACAG-400.2.1
#> [1,] 4.845520 4.332661
#> [2,] 3.785788 3.627688
#> [3,] 3.852729 3.774194
#> [4,] 4.319258 4.193548
#> [5,] 4.996910 5.252688
#> [6,] 4.849640 3.945565
#> [7,] 4.610711 5.095430
#> [8,] 4.997940 4.135753
#> [9,] 4.335736 4.037634
#> [10,] 4.716787 3.793011
#> [11,] 4.230690 4.106183
#> [12,] 4.670443 4.002016
#> [13,] 4.668383 3.938172
#> [14,] 4.839341 4.088038
#> [15,] 4.395469 3.934812
#> [16,] 5.258496 3.930780
#> GTAACTGGTTTGACTG-400.2.1 GTACTCCGTAGCGTCC-400.2.1
#> [1,] 4.134146 4.459309
#> [2,] 4.382114 3.732441
#> [3,] 4.264228 3.605351
#> [4,] 4.303523 4.258640
#> [5,] 4.304878 4.673356
#> [6,] 4.138211 3.957637
#> [7,] 4.439024 5.064660
#> [8,] 4.593496 4.453735
#> [9,] 4.276423 4.201784
#> [10,] 4.345528 4.023411
#> [11,] 4.406504 4.186176
#> [12,] 4.505420 3.735786
#> [13,] 4.430894 4.322185
#> [14,] 4.109756 4.397993
#> [15,] 4.234417 3.516165
#> [16,] 4.189702 4.263099
#> GTACTCCGTCAGGACA-400.2.1 GTAGGCCAGGGAACGG-400.2.1
#> [1,] 4.464286 4.525988
#> [2,] 4.083333 4.824324
#> [3,] 4.428571 4.060291
#> [4,] 4.469048 4.083160
#> [5,] 4.242857 4.378378
#> [6,] 4.163095 4.709979
#> [7,] 4.642857 4.320166
#> [8,] 4.834524 4.952183
#> [9,] 4.438095 4.256757
#> [10,] 4.357143 4.530146
#> [11,] 4.483333 4.562370
#> [12,] 4.680952 4.524948
#> [13,] 4.533333 4.483368
#> [14,] 4.058333 4.040541
#> [15,] 4.485714 4.133056
#> [16,] 4.278571 4.212058
#> GTATCTTAGGAGCGAG-400.2.1 GTATCTTGTGGTCCGT-400.2.1
#> [1,] 4.631918 4.529172
#> [2,] 3.922780 4.759837
#> [3,] 4.468468 4.210312
#> [4,] 4.039897 4.305292
#> [5,] 4.571429 4.284939
#> [6,] 4.374517 4.274084
#> [7,] 4.029601 4.271370
#> [8,] 4.844273 4.853460
#> [9,] 4.436293 4.385346
#> [10,] 4.054054 4.421981
#> [11,] 4.038610 4.656716
#> [12,] 4.386100 4.343284
#> [13,] 4.904762 4.529172
#> [14,] 4.069498 4.052917
#> [15,] 4.145431 4.124830
#> [16,] 4.453024 4.540027
#> GTCAAGTCAAAGCAAT-400.2.1 GTCCTCACACGCGAAA-400.2.1
#> [1,] 4.227603 4.686695
#> [2,] 3.976594 3.908798
#> [3,] 4.371267 3.782904
#> [4,] 4.522195 3.924177
#> [5,] 4.736077 5.016452
#> [6,] 4.194512 3.962089
#> [7,] 4.516546 4.902361
#> [8,] 4.729621 4.257153
#> [9,] 4.201776 4.322604
#> [10,] 3.938660 3.972818
#> [11,] 4.367232 4.272890
#> [12,] 4.078289 4.145565
#> [13,] 4.405165 4.230329
#> [14,] 4.125908 4.659871
#> [15,] 4.190476 3.684907
#> [16,] 4.029863 3.909871
#> GTCGGGTAGAATGTTG-400.2.1 GTCGGGTTCTTGCCGT-400.2.1
#> [1,] 3.963938 4.418345
#> [2,] 4.166667 3.640567
#> [3,] 4.565302 3.806861
#> [4,] 4.237817 4.170022
#> [5,] 5.021442 5.119314
#> [6,] 4.342105 3.856078
#> [7,] 4.571150 4.504101
#> [8,] 4.658869 4.396719
#> [9,] 4.307992 4.242356
#> [10,] 4.190058 3.712155
#> [11,] 4.270955 3.651752
#> [12,] 4.515595 4.086503
#> [13,] 4.284600 4.340045
#> [14,] 4.302144 4.225205
#> [15,] 4.129630 3.935123
#> [16,] 4.256335 4.112603
#> GTCTTCGTCTGACCTC-400.2.1 GTGAAGGAGTTAAGTG-400.2.1
#> [1,] 4.486789 4.412459
#> [2,] 3.365893 3.741857
#> [3,] 3.768615 4.076954
#> [4,] 3.965572 4.243893
#> [5,] 5.367494 5.145765
#> [6,] 3.835068 3.904316
#> [7,] 5.098479 5.019137
#> [8,] 4.196157 4.415717
#> [9,] 4.154524 4.158388
#> [10,] 3.497998 3.912866
#> [11,] 4.131305 4.291531
#> [12,] 3.864692 4.082248
#> [13,] 4.100080 4.363599
#> [14,] 4.284227 4.388844
#> [15,] 4.023219 3.653094
#> [16,] 4.483587 4.325733
#> GTGCAGCTCGGCATCG-400.2.1 GTGCAGCTCGTTTGCC-400.2.1
#> [1,] 4.223977 4.383914
#> [2,] 3.826992 3.637645
#> [3,] 4.049533 4.280265
#> [4,] 4.150036 4.045605
#> [5,] 4.717157 4.816750
#> [6,] 3.974156 3.976783
#> [7,] 4.699210 4.473466
#> [8,] 4.304379 4.150083
#> [9,] 4.166547 4.170813
#> [10,] 4.043073 3.892206
#> [11,] 4.086145 4.106965
#> [12,] 4.117014 4.255390
#> [13,] 4.538406 4.140962
#> [14,] 4.084709 4.328358
#> [15,] 3.861450 4.640962
#> [16,] 4.434314 4.257048
#> GTGCATAAGAACAACT-400.2.1 GTGCGGTAGTGGGTTG-400.2.1
#> [1,] 4.367292 4.438914
#> [2,] 3.685433 3.553733
#> [3,] 3.553172 3.775452
#> [4,] 4.139410 4.434389
#> [5,] 5.496872 4.879525
#> [6,] 3.982127 4.023756
#> [7,] 5.221626 5.223982
#> [8,] 3.966041 4.338801
#> [9,] 4.286863 4.222851
#> [10,] 3.774799 4.127828
#> [11,] 3.949062 4.265271
#> [12,] 3.976765 4.014140
#> [13,] 4.114388 4.286765
#> [14,] 4.436997 4.182127
#> [15,] 3.616622 3.537896
#> [16,] 3.662198 3.863688
#> GTGGGTCAGATCTGAA-400.2.1 GTGGGTCCACAGATTC-400.2.1
#> [1,] 4.956710 4.095731
#> [2,] 3.449351 4.157827
#> [3,] 3.849351 3.941785
#> [4,] 4.830303 4.000000
#> [5,] 5.293506 4.394567
#> [6,] 3.833766 4.292367
#> [7,] 4.561905 4.201811
#> [8,] 4.159307 4.551100
#> [9,] 4.099567 4.842173
#> [10,] 3.506494 4.091850
#> [11,] 3.600000 4.258732
#> [12,] 3.793939 4.495472
#> [13,] 4.365368 4.584735
#> [14,] 4.216450 4.058215
#> [15,] 4.016450 3.921087
#> [16,] 3.650216 4.530401
#> GTGGGTCCATAGGATA-400.2.1 GTGTGCGAGATCTGAA-400.2.1
#> [1,] 4.665773 4.654028
#> [2,] 3.785523 4.219194
#> [3,] 3.541555 4.110190
#> [4,] 4.415550 4.360190
#> [5,] 5.230563 4.731043
#> [6,] 3.923146 4.489336
#> [7,] 4.747989 4.308057
#> [8,] 4.700626 4.907583
#> [9,] 4.316354 4.550948
#> [10,] 3.593387 4.418246
#> [11,] 3.794459 4.197867
#> [12,] 3.993744 4.545024
#> [13,] 4.554960 4.559242
#> [14,] 4.018767 4.148104
#> [15,] 3.684540 4.136256
#> [16,] 4.138517 4.927725
#> GTGTTAGTCTTGTTTG-400.2.1 GTTACAGGTCGTTGTA-400.2.1
#> [1,] 4.667324 4.638049
#> [2,] 3.855358 4.288462
#> [3,] 4.194609 4.197115
#> [4,] 4.456936 3.981456
#> [5,] 4.885602 4.415522
#> [6,] 3.938856 4.322115
#> [7,] 4.408284 4.160714
#> [8,] 4.523340 4.824176
#> [9,] 4.279421 4.286401
#> [10,] 3.596976 4.034341
#> [11,] 4.193294 4.069368
#> [12,] 4.005260 4.103022
#> [13,] 4.071663 4.377060
#> [14,] 4.069691 3.989011
#> [15,] 4.111769 4.186813
#> [16,] 4.408284 4.708791
#> GTTCTCGAGGTACTCT-400.2.1 TAAACCGTCGTCTGCT-400.2.1
#> [1,] 4.594547 4.624878
#> [2,] 3.647318 4.008815
#> [3,] 3.919085 3.785504
#> [4,] 4.178540 4.306562
#> [5,] 4.802111 4.608227
#> [6,] 4.021108 4.685602
#> [7,] 4.258575 3.969638
#> [8,] 4.609499 4.680705
#> [9,] 4.388742 4.432909
#> [10,] 3.814424 4.219393
#> [11,] 4.194371 4.176298
#> [12,] 4.413369 4.532811
#> [13,] 4.447669 4.542605
#> [14,] 3.924362 4.540646
#> [15,] 3.934916 4.059745
#> [16,] 3.970097 4.835455
#> TAAGAGACACGAAAGC-400.2.1 TAAGCGTCAGCTCGCA-400.2.1
#> [1,] 4.449383 4.647059
#> [2,] 4.464198 4.592246
#> [3,] 3.964198 4.034759
#> [4,] 4.295062 4.471925
#> [5,] 4.345679 4.451872
#> [6,] 4.581481 4.576203
#> [7,] 4.354321 4.053476
#> [8,] 4.696296 4.954545
#> [9,] 4.462963 5.454545
#> [10,] 4.418519 4.223262
#> [11,] 4.232099 4.208556
#> [12,] 4.432099 4.564171
#> [13,] 4.481481 4.872995
#> [14,] 4.270370 4.086898
#> [15,] 4.285185 3.917112
#> [16,] 4.911111 4.906417
#> TAAGCGTGTGCACGAA-400.2.1 TAAGTGCAGATGTAAC-400.2.1
#> [1,] 4.356031 4.402620
#> [2,] 4.361868 3.794419
#> [3,] 4.365759 3.996014
#> [4,] 4.194553 4.451595
#> [5,] 4.516213 5.022210
#> [6,] 4.336576 3.902620
#> [7,] 4.271725 4.555239
#> [8,] 4.714008 4.351936
#> [9,] 4.396887 4.382688
#> [10,] 4.051881 3.764806
#> [11,] 4.134890 3.926538
#> [12,] 4.043450 4.210137
#> [13,] 4.458495 4.538155
#> [14,] 4.338521 4.195330
#> [15,] 4.082361 3.887244
#> [16,] 4.595331 3.990319
#> TACACGACAATGAATG-400.2.1 TACACGATCAAGATCC-400.2.1
#> [1,] 4.539799 4.693047
#> [2,] 4.447392 4.014053
#> [3,] 4.081427 4.045118
#> [4,] 4.067704 4.099852
#> [5,] 4.377859 4.737426
#> [6,] 4.272644 3.985207
#> [7,] 4.292772 4.186391
#> [8,] 5.026532 4.509615
#> [9,] 4.717292 4.073225
#> [10,] 4.449222 3.696746
#> [11,] 4.325709 3.979290
#> [12,] 4.359561 3.986686
#> [13,] 4.458371 4.446006
#> [14,] 4.100640 3.952663
#> [15,] 4.033852 4.111686
#> [16,] 4.447392 4.542899
#> TACAGTGAGCAAATCA-400.2.1 TACCTATCATTCACTT-400.2.1
#> [1,] 4.805508 4.125966
#> [2,] 4.370912 4.484544
#> [3,] 4.163511 4.148377
#> [4,] 4.203959 4.284389
#> [5,] 4.314114 4.350850
#> [6,] 4.467298 4.475270
#> [7,] 4.288296 4.197063
#> [8,] 4.820998 4.878671
#> [9,] 4.238382 4.780526
#> [10,] 4.322719 4.467543
#> [11,] 4.478485 4.115147
#> [12,] 4.317556 4.482226
#> [13,] 4.288296 4.093509
#> [14,] 3.903614 4.276662
#> [15,] 4.074010 4.403400
#> [16,] 4.320998 4.469088
#> TACCTATGTGTTTGGT-400.2.1 TACCTATGTTACTGAC-400.2.1
#> [1,] 4.193211 4.340025
#> [2,] 4.266319 4.023212
#> [3,] 4.455614 4.090339
#> [4,] 4.298303 4.018193
#> [5,] 4.840731 5.069009
#> [6,] 4.431462 3.971769
#> [7,] 4.025457 4.771016
#> [8,] 5.100522 4.180050
#> [9,] 4.885117 4.169385
#> [10,] 4.146867 4.047679
#> [11,] 4.548956 4.240276
#> [12,] 4.595953 4.063363
#> [13,] 4.299608 4.026976
#> [14,] 4.282637 4.420954
#> [15,] 4.231723 3.912798
#> [16,] 4.734334 4.271644
#> TACCTTATCTGTCTCG-400.2.1 TACGGTAGTTCAGACT-400.2.1
#> [1,] 4.448790 4.178893
#> [2,] 3.944134 4.312741
#> [3,] 3.873371 3.983269
#> [4,] 4.101179 3.885457
#> [5,] 5.270019 4.649936
#> [6,] 3.714463 4.338481
#> [7,] 4.920546 3.990991
#> [8,] 4.399131 4.965251
#> [9,] 4.196151 4.772201
#> [10,] 3.871508 4.207207
#> [11,] 3.826195 4.469755
#> [12,] 4.003724 4.809524
#> [13,] 4.277467 4.314028
#> [14,] 4.135940 3.857143
#> [15,] 3.956549 4.190476
#> [16,] 4.490379 4.630631
#> TACTCATAGGCCATAG-400.2.1 TACTCATGTGTGACCC-400.2.1
#> [1,] 4.812546 4.118501
#> [2,] 3.779336 3.982670
#> [3,] 4.171218 4.123653
#> [4,] 3.948339 4.011710
#> [5,] 4.580074 5.235129
#> [6,] 4.050185 4.038407
#> [7,] 4.582288 4.915222
#> [8,] 4.491513 4.334895
#> [9,] 4.236900 4.092740
#> [10,] 4.118081 3.742389
#> [11,] 4.178598 4.178923
#> [12,] 4.309225 4.190632
#> [13,] 4.046494 4.365340
#> [14,] 4.171956 4.187822
#> [15,] 3.975646 4.032319
#> [16,] 3.983764 4.395785
#> TACTCATTCGGAAACG-400.2.1 TACTTACAGTAGCCGA-400.2.1
#> [1,] 4.552573 4.978740
#> [2,] 4.441834 3.729803
#> [3,] 4.171141 3.967143
#> [4,] 4.134228 4.101276
#> [5,] 4.743848 5.195980
#> [6,] 4.578300 3.892153
#> [7,] 4.505593 4.662157
#> [8,] 4.704698 4.340162
#> [9,] 4.682327 3.977194
#> [10,] 4.272931 3.619637
#> [11,] 4.345638 4.107460
#> [12,] 4.442953 3.935446
#> [13,] 4.647651 4.133359
#> [14,] 4.335570 4.183997
#> [15,] 4.025727 4.199072
#> [16,] 4.765101 4.177812
#> TACTTGTAGACAAGCC-400.2.1 TACTTGTCACACATGT-400.2.1
#> [1,] 4.381679 4.449107
#> [2,] 3.942748 4.439286
#> [3,] 4.236641 4.333036
#> [4,] 4.032269 4.259821
#> [5,] 5.188411 4.246429
#> [6,] 3.981263 4.150893
#> [7,] 4.794934 4.192857
#> [8,] 4.504164 4.680357
#> [9,] 4.264747 5.045536
#> [10,] 3.965649 4.716964
#> [11,] 4.328591 4.157143
#> [12,] 4.386537 4.808929
#> [13,] 4.361901 4.682143
#> [14,] 4.259889 4.303571
#> [15,] 4.030187 4.674107
#> [16,] 4.411520 4.326786
#> TACTTGTCAGACAAAT-400.2.1 TAGCCGGTCGGCATCG-400.2.1
#> [1,] 4.382185 4.188051
#> [2,] 4.227861 4.048972
#> [3,] 4.153806 3.874633
#> [4,] 4.175039 4.217434
#> [5,] 4.547385 4.579824
#> [6,] 4.341274 4.460333
#> [7,] 4.180735 4.381978
#> [8,] 4.569653 4.814887
#> [9,] 4.754013 4.388834
#> [10,] 4.254272 4.262488
#> [11,] 4.035215 4.224290
#> [12,] 4.352667 4.777669
#> [13,] 4.398239 4.264447
#> [14,] 4.178146 3.973555
#> [15,] 4.179182 4.040157
#> [16,] 4.612118 4.414300
#> TAGGCATAGGCTCAGA-400.2.1 TAGGCATGTAGAGCTG-400.2.1
#> [1,] 4.251295 4.809140
#> [2,] 4.242228 4.421147
#> [3,] 4.272021 4.312724
#> [4,] 4.498705 4.279570
#> [5,] 4.509067 4.621864
#> [6,] 4.185233 4.582437
#> [7,] 3.936528 4.400538
#> [8,] 4.321244 4.932796
#> [9,] 4.207254 4.431004
#> [10,] 4.562176 4.219534
#> [11,] 4.084197 4.186380
#> [12,] 4.174870 4.675627
#> [13,] 4.165803 4.417563
#> [14,] 4.597150 4.313620
#> [15,] 4.335492 4.214158
#> [16,] 4.481865 4.622760
#> TATCAGGTCAACCATG-400.2.1 TATCTCAGTGATGCCC-400.2.1
#> [1,] 4.594623 4.387054
#> [2,] 4.218766 4.287979
#> [3,] 4.157090 4.093791
#> [4,] 4.167106 4.256275
#> [5,] 4.597786 4.698811
#> [6,] 3.948867 4.318362
#> [7,] 4.176067 4.166446
#> [8,] 4.558250 4.785997
#> [9,] 4.167106 4.544254
#> [10,] 3.923036 4.339498
#> [11,] 4.218239 4.210040
#> [12,] 4.282024 4.476882
#> [13,] 4.403268 4.299868
#> [14,] 3.852399 4.022457
#> [15,] 3.989457 4.310436
#> [16,] 4.680548 4.221929
#> TCAACGAAGGCACATG-400.2.1 TCACAAGGTCACTGGC-400.2.1
#> [1,] 4.447337 4.246493
#> [2,] 4.504142 4.125251
#> [3,] 4.275740 4.275551
#> [4,] 4.443787 4.055110
#> [5,] 4.280473 4.849699
#> [6,] 4.608284 4.127255
#> [7,] 4.293491 4.383768
#> [8,] 4.523077 4.455912
#> [9,] 4.850888 4.192385
#> [10,] 4.375148 4.104208
#> [11,] 4.267456 4.046092
#> [12,] 4.515976 4.419840
#> [13,] 4.570414 4.153307
#> [14,] 4.266272 4.215431
#> [15,] 4.243787 4.073146
#> [16,] 4.682840 4.448898
#> TCACGAAAGATCTGCT-400.2.1 TCAGATGAGAATTCCC-400.2.1
#> [1,] 3.870152 4.273177
#> [2,] 4.827150 4.401731
#> [3,] 4.226813 4.490729
#> [4,] 4.155143 4.131026
#> [5,] 4.747892 4.148331
#> [6,] 3.828836 3.975278
#> [7,] 3.845700 4.194067
#> [8,] 5.504216 4.800989
#> [9,] 3.975548 4.800989
#> [10,] 3.876897 4.194067
#> [11,] 4.516863 4.396786
#> [12,] 3.654300 4.525340
#> [13,] 4.230185 4.402967
#> [14,] 5.057336 4.222497
#> [15,] 3.728499 4.067985
#> [16,] 4.441821 4.809642
#> TCAGCTCTCCACGTTC-400.2.1 TCAGGATTCGCTGATA-400.2.1
#> [1,] 4.251928 4.349131
#> [2,] 4.334190 4.101106
#> [3,] 4.212511 4.226698
#> [4,] 4.334190 4.617694
#> [5,] 4.444730 4.679305
#> [6,] 4.362468 4.069510
#> [7,] 4.029135 4.323065
#> [8,] 5.069409 4.734597
#> [9,] 4.475578 4.515008
#> [10,] 4.058269 4.074250
#> [11,] 3.949443 4.057662
#> [12,] 4.178235 4.096367
#> [13,] 4.530420 4.374408
#> [14,] 4.071123 4.104265
#> [15,] 4.286204 4.008689
#> [16,] 4.218509 4.512638
#> TCATTACAGTACGCGA-400.2.1 TCATTACCACCATCCT-400.2.1
#> [1,] 4.350457 4.296974
#> [2,] 4.131279 4.419924
#> [3,] 4.190639 4.137453
#> [4,] 4.408676 3.962169
#> [5,] 4.541096 5.133670
#> [6,] 4.204338 4.442623
#> [7,] 4.210046 4.075662
#> [8,] 4.759132 4.810214
#> [9,] 4.565068 4.574401
#> [10,] 4.218037 4.366330
#> [11,] 4.162100 4.099622
#> [12,] 4.559361 4.532156
#> [13,] 4.642694 4.462169
#> [14,] 3.962329 4.111602
#> [15,] 3.795662 4.409206
#> [16,] 4.415525 4.544767
#> TCATTTGAGATCGGGT-400.2.1 TCATTTGCAGGCAGTA-400.2.1
#> [1,] 4.297521 4.807553
#> [2,] 4.279959 3.606391
#> [3,] 4.258781 3.897603
#> [4,] 4.060950 4.034858
#> [5,] 4.959711 4.809005
#> [6,] 4.073864 4.246914
#> [7,] 4.335227 4.508351
#> [8,] 5.211777 4.444444
#> [9,] 4.324380 4.326797
#> [10,] 3.952479 3.782861
#> [11,] 4.282541 4.209877
#> [12,] 3.927686 4.330428
#> [13,] 4.204029 4.288308
#> [14,] 4.369835 4.090051
#> [15,] 4.244835 3.799564
#> [16,] 4.632231 4.227306
#> TCATTTGGTAGTGAAT-400.2.1 TCATTTGTCCGCGTTT-400.2.1
#> [1,] 4.584291 4.139303
#> [2,] 3.850575 4.080431
#> [3,] 4.107280 4.024046
#> [4,] 4.225415 4.008292
#> [5,] 5.234994 4.494196
#> [6,] 3.967433 4.270315
#> [7,] 4.738186 4.471808
#> [8,] 4.045977 4.684080
#> [9,] 4.178161 4.499171
#> [10,] 3.837803 4.263682
#> [11,] 3.978289 4.145937
#> [12,] 3.929757 4.564677
#> [13,] 4.073436 4.347430
#> [14,] 4.261814 4.111111
#> [15,] 3.808429 4.099502
#> [16,] 4.394636 4.753731
#> TCCACACCAAAGTGCG-400.2.1 TCCACACGTGAAATCA-400.2.1
#> [1,] 4.560147 4.543557
#> [2,] 3.683196 4.381125
#> [3,] 3.910927 4.468240
#> [4,] 4.055096 4.395644
#> [5,] 4.994490 4.507260
#> [6,] 3.919192 4.301270
#> [7,] 4.591368 4.251361
#> [8,] 4.599633 4.872051
#> [9,] 4.101928 4.462795
#> [10,] 4.031221 4.514519
#> [11,] 3.964187 4.382940
#> [12,] 3.815427 4.529946
#> [13,] 4.271809 4.507260
#> [14,] 4.318641 4.139746
#> [15,] 4.137741 4.681488
#> [16,] 4.605142 4.321234
#> TCGAGGCGTGCCTGTG-400.2.1 TCGAGGCTCAGCTCGG-400.2.1
#> [1,] 4.515513 4.474390
#> [2,] 4.407319 4.456098
#> [3,] 4.052506 4.164634
#> [4,] 4.081941 3.735366
#> [5,] 5.147176 4.297561
#> [6,] 4.640414 4.453659
#> [7,] 4.357200 4.310976
#> [8,] 4.944312 4.785366
#> [9,] 4.680986 4.921951
#> [10,] 4.351631 4.209756
#> [11,] 4.087510 4.524390
#> [12,] 4.420843 4.498780
#> [13,] 4.349244 4.630488
#> [14,] 4.101034 4.470732
#> [15,] 4.046142 4.180488
#> [16,] 4.687351 4.781707
#> TCGCGTTAGTTACCCA-400.2.1 TCGCGTTGTCCCGACA-400.2.1
#> [1,] 4.614325 4.520175
#> [2,] 3.537879 3.982456
#> [3,] 3.752755 3.978070
#> [4,] 3.922176 4.041228
#> [5,] 5.571625 5.033333
#> [6,] 3.542700 3.929825
#> [7,] 5.497934 4.521930
#> [8,] 4.242424 4.642105
#> [9,] 3.935950 4.287719
#> [10,] 3.702479 3.860526
#> [11,] 4.077135 4.578070
#> [12,] 4.136364 3.810526
#> [13,] 4.256887 4.108772
#> [14,] 4.226584 4.325439
#> [15,] 3.887741 3.616667
#> [16,] 4.313361 4.314035
#> TCGGGACAGTCGTACT-400.2.1 TCGGGACCAATCCGAT-400.2.1
#> [1,] 4.457702 4.454321
#> [2,] 3.873903 4.251235
#> [3,] 4.173184 3.889506
#> [4,] 4.266959 4.369136
#> [5,] 4.915004 4.495679
#> [6,] 4.132482 4.150617
#> [7,] 4.723065 4.350617
#> [8,] 4.478851 4.599383
#> [9,] 4.047885 5.033951
#> [10,] 4.035116 4.253704
#> [11,] 4.217478 4.202469
#> [12,] 4.089385 4.534568
#> [13,] 4.207502 4.814198
#> [14,] 4.134078 4.191358
#> [15,] 4.124900 3.831481
#> [16,] 4.258180 4.585802
#> TCGGGACCATTCTTAC-400.2.1 TCGGGACGTTTGGCGC-400.2.1
#> [1,] 4.439163 4.545455
#> [2,] 3.803232 4.048008
#> [3,] 3.767110 4.108274
#> [4,] 4.088403 4.297242
#> [5,] 5.158745 5.226762
#> [6,] 4.048479 3.879469
#> [7,] 4.714829 5.017365
#> [8,] 4.081749 4.222676
#> [9,] 3.948669 3.880490
#> [10,] 3.738593 3.788560
#> [11,] 3.862167 4.342186
#> [12,] 4.014259 4.042901
#> [13,] 4.297529 4.118488
#> [14,] 4.114068 4.150153
#> [15,] 4.022814 3.895812
#> [16,] 4.292776 4.468846
#> TCGTAGACAAAGGCGT-400.2.1 TCTATTGGTCTAGCCG-400.2.1
#> [1,] 4.493347 4.263077
#> [2,] 4.395087 4.305385
#> [3,] 3.763562 4.221538
#> [4,] 4.195496 4.350769
#> [5,] 4.404299 4.574615
#> [6,] 4.289662 4.308462
#> [7,] 4.149437 4.345385
#> [8,] 4.987718 4.781538
#> [9,] 4.437052 4.406154
#> [10,] 4.703173 4.302308
#> [11,] 4.291709 4.336923
#> [12,] 4.673490 4.238462
#> [13,] 4.640737 4.477692
#> [14,] 4.186285 4.193077
#> [15,] 4.069601 4.026923
#> [16,] 4.204708 4.642308
#> TCTCTAAAGGGTCGAT-400.2.1 TCTCTAAGTCGACTGC-400.2.1
#> [1,] 4.392290 4.496310
#> [2,] 3.823583 4.603321
#> [3,] 3.745125 4.030135
#> [4,] 4.048980 4.065806
#> [5,] 4.895692 4.474785
#> [6,] 4.127891 4.404674
#> [7,] 4.507483 4.427429
#> [8,] 4.523810 5.006150
#> [9,] 4.122902 4.658057
#> [10,] 4.062132 4.318573
#> [11,] 3.963719 4.361624
#> [12,] 4.302948 4.714637
#> [13,] 4.169615 4.430504
#> [14,] 4.211338 4.402214
#> [15,] 4.280726 4.679582
#> [16,] 4.310658 4.774293
#> TCTGAGAAGGGAACGG-400.2.1 TCTGGAAAGAGTCGGT-400.2.1
#> [1,] 4.283619 4.223294
#> [2,] 4.067645 4.271537
#> [3,] 4.363488 4.058580
#> [4,] 4.241239 4.290834
#> [5,] 4.428688 4.470021
#> [6,] 3.842706 4.180565
#> [7,] 4.374898 4.223294
#> [8,] 4.590057 4.515507
#> [9,] 4.210269 4.752584
#> [10,] 4.066015 4.310131
#> [11,] 4.131214 4.160579
#> [12,] 4.414018 4.588560
#> [13,] 4.048900 4.688491
#> [14,] 3.788101 4.211578
#> [15,] 4.528932 4.209511
#> [16,] 4.449063 4.432805
#> TCTGGAAGTGTTTGTG-400.2.1 TCTTCGGAGAGGACGG-400.2.1
#> [1,] 3.997396 4.194514
#> [2,] 4.125000 4.487531
#> [3,] 4.033854 4.173317
#> [4,] 4.153646 4.223192
#> [5,] 4.828125 4.920200
#> [6,] 3.951823 4.285536
#> [7,] 4.998698 4.235661
#> [8,] 4.518229 4.936409
#> [9,] 4.186198 4.765586
#> [10,] 3.983073 4.496259
#> [11,] 4.000000 4.302993
#> [12,] 3.829427 4.197007
#> [13,] 4.178385 4.618454
#> [14,] 4.316406 4.219451
#> [15,] 3.996094 4.143392
#> [16,] 4.239583 4.492519
#> TCTTTCCAGATATGCA-400.2.1 TCTTTCCAGGTGTGGT-400.2.1
#> [1,] 4.290432 4.043103
#> [2,] 4.027096 4.668719
#> [3,] 4.444539 3.916256
#> [4,] 4.072820 3.786946
#> [5,] 4.931414 4.593596
#> [6,] 4.004234 3.753695
#> [7,] 4.400508 4.033251
#> [8,] 4.817104 5.199507
#> [9,] 4.240474 4.663793
#> [10,] 3.697714 4.434729
#> [11,] 4.255715 4.818966
#> [12,] 3.983065 4.187192
#> [13,] 4.281964 4.130542
#> [14,] 4.450466 4.586207
#> [15,] 4.093141 3.816502
#> [16,] 4.696020 4.475369
#> TCTTTCCCAAATACAG-400.2.1 TGACTAGGTTCACCTC-400.2.1
#> [1,] 4.844961 4.189141
#> [2,] 4.195736 3.678998
#> [3,] 4.116279 4.191527
#> [4,] 4.120155 3.670048
#> [5,] 4.713178 4.711217
#> [6,] 4.642442 4.199284
#> [7,] 4.576550 4.862768
#> [8,] 5.132752 4.307279
#> [9,] 4.809109 4.084129
#> [10,] 4.384690 3.857995
#> [11,] 4.500000 4.218377
#> [12,] 4.591085 4.295346
#> [13,] 4.142442 4.177208
#> [14,] 4.135659 4.323986
#> [15,] 4.164729 4.196897
#> [16,] 4.593992 4.020286
#> TGACTTTTCTATCCCG-400.2.1 TGAGCATTCGCAAACT-400.2.1
#> [1,] 4.233216 4.153759
#> [2,] 4.411072 4.159453
#> [3,] 4.254417 4.112756
#> [4,] 4.181390 3.810934
#> [5,] 4.541814 4.765376
#> [6,] 4.138987 4.023918
#> [7,] 4.061249 4.375854
#> [8,] 5.040047 4.456720
#> [9,] 4.286219 4.405467
#> [10,] 4.028269 4.559226
#> [11,] 3.884570 4.031891
#> [12,] 4.259128 4.528474
#> [13,] 4.303887 4.552392
#> [14,] 4.111896 4.328018
#> [15,] 3.942285 4.289294
#> [16,] 4.535925 4.820046
#> TGAGGGAAGAAGGCCT-400.2.1 TGAGGGATCAAGATCC-400.2.1
#> [1,] 4.505960 4.948692
#> [2,] 4.168212 4.508048
#> [3,] 3.990287 4.272636
#> [4,] 4.284327 4.310865
#> [5,] 5.203091 4.214286
#> [6,] 4.172185 4.613682
#> [7,] 4.658720 4.162978
#> [8,] 4.422075 4.725352
#> [9,] 4.064901 4.520121
#> [10,] 4.111700 5.218310
#> [11,] 4.363797 4.296781
#> [12,] 3.941722 4.450704
#> [13,] 4.166887 4.345070
#> [14,] 4.654305 4.246479
#> [15,] 3.743046 3.866197
#> [16,] 4.322737 4.347082
#> TGCCCTAAGGATTCGG-400.2.1 TGCCCTACACATCCAA-400.2.1
#> [1,] 4.300339 4.379704
#> [2,] 4.270508 4.136830
#> [3,] 3.719322 4.150513
#> [4,] 3.764746 4.274800
#> [5,] 4.751864 4.899658
#> [6,] 4.190508 4.051311
#> [7,] 4.227797 4.188141
#> [8,] 4.570847 4.993158
#> [9,] 4.509831 4.475485
#> [10,] 4.091525 4.263398
#> [11,] 3.961356 4.086659
#> [12,] 4.488814 4.442417
#> [13,] 4.795932 4.540479
#> [14,] 4.129492 3.973774
#> [15,] 4.023729 4.031927
#> [16,] 4.593220 4.556442
#> TGGCCAGGTAGGGTAC-400.2.1 TGGCCAGTCGAGGTAG-400.2.1
#> [1,] 4.228715 4.749068
#> [2,] 4.265442 4.118012
#> [3,] 4.372287 4.263354
#> [4,] 4.084307 4.165217
#> [5,] 4.680301 4.849689
#> [6,] 4.204508 4.077019
#> [7,] 4.599332 4.322981
#> [8,] 4.499165 4.304348
#> [9,] 4.393990 4.195031
#> [10,] 4.242070 4.120497
#> [11,] 4.533389 4.008696
#> [12,] 4.449082 4.607453
#> [13,] 4.418197 4.573913
#> [14,] 3.991653 3.845963
#> [15,] 4.401503 4.274534
#> [16,] 4.835559 4.547826
#> TGGCGCAAGACATAAC-400.2.1 TGGCGCAGTGAAATCA-400.2.1
#> [1,] 4.090340 4.426892
#> [2,] 4.586762 4.244673
#> [3,] 3.869410 4.164585
#> [4,] 4.019678 3.919177
#> [5,] 4.820215 5.031594
#> [6,] 4.044723 4.111683
#> [7,] 4.502683 4.034533
#> [8,] 4.547406 4.526819
#> [9,] 4.539356 4.420279
#> [10,] 4.396243 4.096988
#> [11,] 4.243292 4.108009
#> [12,] 4.819320 4.058780
#> [13,] 4.198569 4.598824
#> [14,] 4.200358 4.111683
#> [15,] 4.357782 3.934607
#> [16,] 4.781753 4.632623
#> TGGCTGGCACGTAAGG-400.2.1 TGGCTGGTCGAGAGCA-400.2.1
#> [1,] 4.270396 4.234848
#> [2,] 4.043124 4.088384
#> [3,] 4.130536 3.816378
#> [4,] 4.151515 4.033189
#> [5,] 4.724942 5.112915
#> [6,] 4.079254 4.513348
#> [7,] 4.388112 4.690837
#> [8,] 4.550117 4.023810
#> [9,] 4.899767 3.998196
#> [10,] 4.109557 4.172799
#> [11,] 4.170163 4.070346
#> [12,] 4.268065 4.056277
#> [13,] 4.715618 4.503608
#> [14,] 4.293706 4.192280
#> [15,] 3.868298 3.687951
#> [16,] 4.468531 4.117605
#> TGGGAAGAGACACGAC-400.2.1 TGGGCGTTCAGGCCCA-400.2.1
#> [1,] 4.088599 4.381395
#> [2,] 4.345277 4.349767
#> [3,] 3.973290 4.401860
#> [4,] 4.392182 4.255814
#> [5,] 4.705537 5.106047
#> [6,] 4.362215 4.520930
#> [7,] 4.035179 4.226047
#> [8,] 4.940065 5.045581
#> [9,] 5.351792 4.565581
#> [10,] 4.090554 4.293953
#> [11,] 4.575896 4.695814
#> [12,] 4.246254 4.328372
#> [13,] 3.949837 4.735814
#> [14,] 4.248208 4.327442
#> [15,] 4.178502 4.163721
#> [16,] 4.408469 4.605581
#> TGGTTAGAGATACACA-400.2.1 TGGTTAGGTAGCCTCG-400.2.1
#> [1,] 4.335251 4.567818
#> [2,] 4.212818 3.621455
#> [3,] 4.146261 4.040691
#> [4,] 4.245686 4.607275
#> [5,] 4.829088 4.780518
#> [6,] 4.096138 3.827374
#> [7,] 4.368118 4.829223
#> [8,] 4.981101 4.133785
#> [9,] 4.531635 4.138718
#> [10,] 4.188989 3.793465
#> [11,] 4.128184 4.129470
#> [12,] 4.377157 3.929716
#> [13,] 4.475760 4.162762
#> [14,] 4.087099 4.096178
#> [15,] 3.976171 3.801480
#> [16,] 4.317173 4.255240
#> TGGTTCCCAGAAGCAC-400.2.1 TGGTTCCGTCGACTAT-400.2.1
#> [1,] 4.470955 4.445185
#> [2,] 4.263082 3.695556
#> [3,] 4.066731 4.215556
#> [4,] 4.587614 4.052593
#> [5,] 4.241959 5.071111
#> [6,] 4.191551 3.952593
#> [7,] 4.388382 4.450370
#> [8,] 4.682189 4.591852
#> [9,] 4.693711 4.142222
#> [10,] 4.228997 3.830370
#> [11,] 4.144983 4.582963
#> [12,] 4.447912 4.395556
#> [13,] 4.994719 4.205926
#> [14,] 3.984157 4.172593
#> [15,] 4.372540 3.840741
#> [16,] 4.579453 4.058519
#> TGTATTCCAGAGTGTG-400.2.1 TGTATTCGTAAACACA-400.2.1
#> [1,] 4.340584 4.552403
#> [2,] 4.163926 4.075650
#> [3,] 4.458886 3.892829
#> [4,] 4.227586 4.327029
#> [5,] 4.572944 4.654846
#> [6,] 3.901326 4.401103
#> [7,] 4.221751 4.324665
#> [8,] 4.954907 4.394011
#> [9,] 4.160743 4.491726
#> [10,] 3.870557 3.867612
#> [11,] 4.469496 3.874704
#> [12,] 4.171353 4.118991
#> [13,] 4.109284 4.470449
#> [14,] 4.384615 3.977935
#> [15,] 4.088064 4.194641
#> [16,] 4.580371 4.178093
#> TGTGGTAGTGAGTATA-400.2.1 TGTGTTTAGAGGTTAT-400.2.1
#> [1,] 4.525080 4.518797
#> [2,] 4.030950 4.340226
#> [3,] 4.438634 4.412594
#> [4,] 4.268943 4.247180
#> [5,] 4.550694 4.485902
#> [6,] 4.549626 4.001880
#> [7,] 4.017076 4.423872
#> [8,] 5.169691 4.748120
#> [9,] 4.914621 4.233083
#> [10,] 4.307364 4.181391
#> [11,] 4.292423 4.334586
#> [12,] 4.205977 4.487782
#> [13,] 4.364995 4.087406
#> [14,] 3.998933 4.153195
#> [15,] 4.021345 3.960526
#> [16,] 4.289221 4.120301
#> TGTGTTTGTGTTTGGT-400.2.1 TGTTCCGAGACTAAGT-400.2.1
#> [1,] 4.576827 4.002608
#> [2,] 4.051716 4.224250
#> [3,] 3.937842 3.894394
#> [4,] 4.081054 4.153846
#> [5,] 4.900050 4.383312
#> [6,] 3.993038 4.129074
#> [7,] 4.684237 4.415906
#> [8,] 4.570860 4.783572
#> [9,] 4.242665 4.130378
#> [10,] 3.995525 4.514993
#> [11,] 4.097961 4.327249
#> [12,] 4.187966 4.328553
#> [13,] 4.118349 4.696219
#> [14,] 4.403282 4.031291
#> [15,] 3.833416 4.122555
#> [16,] 4.238190 4.457627
#> TTAACTCCAGAGTGTG-400.2.1 TTAGGCATCACGACTA-400.2.1
#> [1,] 4.160312 4.286406
#> [2,] 3.991334 3.925707
#> [3,] 4.141248 4.064872
#> [4,] 4.749567 4.072678
#> [5,] 4.516464 5.362046
#> [6,] 4.268631 4.095289
#> [7,] 4.076256 4.971736
#> [8,] 4.983536 4.283984
#> [9,] 5.107452 4.186272
#> [10,] 4.584055 3.967429
#> [11,] 4.220104 4.010498
#> [12,] 4.425477 3.919785
#> [13,] 4.042461 4.286406
#> [14,] 4.616118 4.434455
#> [15,] 4.118718 3.711171
#> [16,] 4.030329 4.130283
#> TTAGTTCAGTAGCGGT-400.2.1 TTATGCTGTCGGATCC-400.2.1
#> [1,] 4.275862 4.256341
#> [2,] 4.509031 4.269293
#> [3,] 4.365353 4.549379
#> [4,] 4.215107 4.259579
#> [5,] 4.392447 5.174312
#> [6,] 4.313629 4.767404
#> [7,] 4.215107 4.230977
#> [8,] 4.888342 4.451700
#> [9,] 5.127258 4.432272
#> [10,] 4.692939 4.620615
#> [11,] 4.233169 4.770642
#> [12,] 4.349754 4.366433
#> [13,] 4.109195 3.983270
#> [14,] 4.387521 4.499730
#> [15,] 4.444171 4.376147
#> [16,] 4.329228 4.539665
#> TTCGGTCTCCCTAATT-400.2.1 TTCTCCTGTGACGCCT-400.2.1
#> [1,] 4.120577 4.084142
#> [2,] 4.456094 4.307443
#> [3,] 4.591088 4.090615
#> [4,] 4.292267 4.454153
#> [5,] 4.660550 4.749730
#> [6,] 4.106160 4.083064
#> [7,] 4.351245 4.632147
#> [8,] 4.294889 4.625674
#> [9,] 4.133683 4.367853
#> [10,] 4.332896 4.540453
#> [11,] 4.285714 5.002157
#> [12,] 4.456094 4.578209
#> [13,] 4.166448 4.508091
#> [14,] 4.656619 4.002157
#> [15,] 4.242464 4.333333
#> [16,] 4.200524 4.358145
#> TTCTCCTGTTCACGGC-400.2.1 TTCTCCTTCCTAGAAC-400.2.1
#> [1,] 4.261287 4.454744
#> [2,] 4.259594 4.282443
#> [3,] 4.097065 4.224646
#> [4,] 3.998307 4.495093
#> [5,] 4.720090 4.841876
#> [6,] 4.308126 4.343511
#> [7,] 4.169865 4.139586
#> [8,] 4.875282 4.517993
#> [9,] 4.449774 4.499455
#> [10,] 4.233070 4.332606
#> [11,] 4.199774 4.183206
#> [12,] 4.232506 4.499455
#> [13,] 4.448081 4.317339
#> [14,] 4.255079 4.098146
#> [15,] 4.034989 4.276990
#> [16,] 4.288939 4.715376
#> TTCTTAGAGGCCATAG-400.2.1 TTGCCGTAGACAATAC-400.2.1
#> [1,] 4.609489 4.354493
#> [2,] 4.413321 3.600989
#> [3,] 4.421533 3.596867
#> [4,] 4.214416 4.408904
#> [5,] 4.385949 5.243199
#> [6,] 4.587591 3.995878
#> [7,] 4.474453 5.060181
#> [8,] 5.040146 4.250618
#> [9,] 4.339416 4.387469
#> [10,] 4.490876 3.565540
#> [11,] 4.315693 3.754328
#> [12,] 4.489964 3.954658
#> [13,] 4.589416 4.338005
#> [14,] 4.179745 4.403957
#> [15,] 4.145985 3.774938
#> [16,] 4.542883 3.997527
#> TTGGAACAGGCAATTA-400.2.1 TTGGAACGTTCACCTC-400.2.1
#> [1,] 4.447627 4.784375
#> [2,] 4.151347 3.627344
#> [3,] 4.290723 4.323438
#> [4,] 4.455323 3.925781
#> [5,] 5.052587 5.153125
#> [6,] 3.979478 3.975000
#> [7,] 4.738777 4.695313
#> [8,] 4.192817 4.610156
#> [9,] 4.183412 4.189063
#> [10,] 3.856349 3.886719
#> [11,] 4.132108 4.385938
#> [12,] 4.091492 4.081250
#> [13,] 4.264643 4.142969
#> [14,] 4.215049 4.327344
#> [15,] 3.944848 4.069531
#> [16,] 4.046174 4.547656
#> TTGGCAAAGATCTGAA-400.2.1 TTGGCAAAGCAAATCA-400.2.1
#> [1,] 4.141596 4.654807
#> [2,] 3.802246 3.850114
#> [3,] 4.119936 4.208176
#> [4,] 3.911753 4.100681
#> [5,] 5.535098 4.863740
#> [6,] 3.775371 4.103709
#> [7,] 5.225431 4.373959
#> [8,] 4.202166 4.392884
#> [9,] 3.870036 4.130204
#> [10,] 3.821500 3.582135
#> [11,] 4.182912 3.901590
#> [12,] 4.162455 4.316427
#> [13,] 4.311272 4.253596
#> [14,] 4.391095 3.750946
#> [15,] 3.895307 4.348221
#> [16,] 4.240273 4.377744
#> TTGGCAACAGACTCGC-400.2.1 TTTACTGGTAGCTCCG-400.2.1
#> [1,] 4.321364 4.877950
#> [2,] 3.874925 3.748576
#> [3,] 3.831837 4.148088
#> [4,] 4.024536 4.358828
#> [5,] 4.733692 4.700570
#> [6,] 3.800718 4.035801
#> [7,] 4.530221 4.406835
#> [8,] 4.359066 4.630594
#> [9,] 4.385398 4.388934
#> [10,] 3.830042 3.692433
#> [11,] 3.911430 4.279902
#> [12,] 4.192101 4.218063
#> [13,] 4.529623 4.335232
#> [14,] 4.252543 4.135069
#> [15,] 3.801317 3.887714
#> [16,] 4.129862 4.276648
#> TTTATGCGTCAGCTAT-400.2.1 TTTGGTTCATTCGACA-400.2.1
#> [1,] 4.289403 4.559125
#> [2,] 4.225289 3.894737
#> [3,] 4.492431 4.065619
#> [4,] 4.463045 4.004101
#> [5,] 4.469279 4.864662
#> [6,] 4.251113 3.885851
#> [7,] 4.321460 4.579631
#> [8,] 4.674978 4.870130
#> [9,] 4.658059 4.224880
#> [10,] 4.376670 3.943951
#> [11,] 4.416741 3.888585
#> [12,] 4.551202 4.393712
#> [13,] 4.535174 4.323992
#> [14,] 4.413179 4.306220
#> [15,] 4.153161 4.040328
#> [16,] 4.539626 4.107314
#> TTTGTCATCTGCGGCA-400.2.1 AAACCTGCAGATGAGC-400.2.2
#> [1,] 4.070381 4.734477
#> [2,] 4.321408 3.270846
#> [3,] 4.136070 3.878179
#> [4,] 4.132551 4.067416
#> [5,] 5.059824 4.692490
#> [6,] 3.748974 4.054997
#> [7,] 4.608798 4.692490
#> [8,] 4.443988 4.361325
#> [9,] 4.065103 4.007096
#> [10,] 3.751320 3.629805
#> [11,] 4.180645 4.151981
#> [12,] 4.353666 4.251331
#> [13,] 4.242229 4.326434
#> [14,] 4.246334 4.076878
#> [15,] 3.882111 4.016558
#> [16,] 4.318475 4.106446
#> AAACGGGAGCCCTAAT-400.2.2 AAACGGGCACACGCTG-400.2.2
#> [1,] 4.364217 4.235391
#> [2,] 4.090096 4.247937
#> [3,] 4.185304 4.217233
#> [4,] 3.994249 4.262793
#> [5,] 4.775080 4.982172
#> [6,] 4.140575 4.053813
#> [7,] 4.083706 5.041928
#> [8,] 4.591054 4.234731
#> [9,] 4.669649 4.272697
#> [10,] 4.000000 4.231760
#> [11,] 4.325240 4.413008
#> [12,] 4.607668 4.257511
#> [13,] 4.380192 4.365467
#> [14,] 3.913099 4.470452
#> [15,] 4.001278 3.851106
#> [16,] 4.748882 4.177286
#> AAACGGGTCCGAACGC-400.2.2 AAAGATGAGCCCAATT-400.2.2
#> [1,] 4.506508 4.435807
#> [2,] 4.296095 4.296820
#> [3,] 4.028200 3.876325
#> [4,] 4.195228 4.150766
#> [5,] 4.555315 4.566549
#> [6,] 4.343818 4.658422
#> [7,] 4.123644 4.181390
#> [8,] 4.609544 4.780919
#> [9,] 4.335141 4.181390
#> [10,] 4.079176 4.567727
#> [11,] 4.233189 4.550059
#> [12,] 4.061822 4.515901
#> [13,] 4.548807 4.237927
#> [14,] 3.951193 3.961131
#> [15,] 4.069414 3.883392
#> [16,] 4.533623 4.148410
#> AAAGATGTCATCGCTC-400.2.2 AAAGATGTCCACGCAG-400.2.2
#> [1,] 4.556117 4.371287
#> [2,] 3.522245 4.078218
#> [3,] 3.771992 4.068317
#> [4,] 4.115268 4.156436
#> [5,] 5.340748 4.750495
#> [6,] 3.991405 4.392079
#> [7,] 4.829120 4.172277
#> [8,] 4.211325 4.905941
#> [9,] 3.819009 4.892079
#> [10,] 3.799292 4.363366
#> [11,] 4.176441 4.059406
#> [12,] 3.771486 4.356436
#> [13,] 3.811931 4.579208
#> [14,] 4.320020 4.443564
#> [15,] 3.876643 4.332673
#> [16,] 4.117796 4.389109
#> AAAGCAATCCTCATTA-400.2.2 AAAGTAGCATGGTTGT-400.2.2
#> [1,] 4.439690 4.404237
#> [2,] 3.860719 3.746690
#> [3,] 4.238962 4.283319
#> [4,] 4.050979 3.702560
#> [5,] 5.105143 5.682259
#> [6,] 4.116067 3.848191
#> [7,] 4.573964 4.918800
#> [8,] 4.279927 4.464254
#> [9,] 4.271734 4.140335
#> [10,] 3.957214 3.556046
#> [11,] 4.286755 4.432480
#> [12,] 4.189349 4.157988
#> [13,] 4.084661 4.102383
#> [14,] 4.425580 4.051192
#> [15,] 3.866636 3.711386
#> [16,] 4.048248 4.777582
#> AAAGTAGTCGTCTGCT-400.2.2 AAATGCCGTAGAGTGC-400.2.2
#> [1,] 4.638234 4.228604
#> [2,] 3.804598 3.902758
#> [3,] 3.805203 4.310208
#> [4,] 4.162129 4.084731
#> [5,] 5.614035 4.845323
#> [6,] 4.180883 3.950526
#> [7,] 5.104658 4.872334
#> [8,] 4.082880 4.679841
#> [9,] 3.990321 4.272960
#> [10,] 3.923170 4.001137
#> [11,] 3.983061 4.328689
#> [12,] 3.757411 4.339778
#> [13,] 4.287356 4.205857
#> [14,] 4.330309 4.162923
#> [15,] 4.042952 3.993176
#> [16,] 4.346642 4.270117
#> AAATGCCGTAGGGACT-400.2.2 AAATGCCTCTTACCGC-400.2.2
#> [1,] 4.693046 4.443073
#> [2,] 4.083933 3.578239
#> [3,] 4.153477 3.895681
#> [4,] 3.940847 4.204711
#> [5,] 5.020783 5.280426
#> [6,] 4.883293 3.904094
#> [7,] 4.611511 4.918116
#> [8,] 4.876099 4.222098
#> [9,] 4.432454 3.864835
#> [10,] 4.214229 3.815480
#> [11,] 4.336531 4.266966
#> [12,] 4.228617 4.063376
#> [13,] 3.888889 3.926528
#> [14,] 3.989608 4.521593
#> [15,] 4.262190 3.916433
#> [16,] 4.499600 4.291643
#> AACCATGAGGACGAAA-400.2.2 AACCGCGGTCGCGTGT-400.2.2
#> [1,] 4.387857 4.350554
#> [2,] 4.199286 3.861624
#> [3,] 4.200000 3.996310
#> [4,] 3.869286 4.513530
#> [5,] 4.479286 5.333333
#> [6,] 4.105000 3.942804
#> [7,] 4.031429 5.253998
#> [8,] 4.819286 4.311193
#> [9,] 4.408571 3.934194
#> [10,] 4.061429 3.738007
#> [11,] 3.910000 4.039975
#> [12,] 4.236429 4.030135
#> [13,] 4.549286 4.089176
#> [14,] 4.120000 4.246617
#> [15,] 4.055000 3.727552
#> [16,] 4.477857 3.851784
#> AACCGCGGTCTTTCAT-400.2.2 AACCGCGGTGTGACGA-400.2.2
#> [1,] 4.572656 4.196673
#> [2,] 3.483178 4.133072
#> [3,] 4.300644 4.361057
#> [4,] 4.254832 4.093933
#> [5,] 4.385111 4.670254
#> [6,] 3.779528 4.238748
#> [7,] 4.513243 4.936399
#> [8,] 4.357194 4.703523
#> [9,] 4.428776 4.304305
#> [10,] 3.960630 4.210372
#> [11,] 3.934145 4.850294
#> [12,] 4.259127 4.761252
#> [13,] 4.291339 4.464775
#> [14,] 4.205440 4.077299
#> [15,] 4.470293 4.443249
#> [16,] 4.118110 4.664384
#> AACTCCCCACCGCTAG-400.2.2 AACTCTTAGACACGAC-400.2.2
#> [1,] 4.588806 4.636574
#> [2,] 3.842376 3.803241
#> [3,] 3.985722 3.483796
#> [4,] 3.856653 3.688272
#> [5,] 5.339806 5.285494
#> [6,] 3.886922 3.509259
#> [7,] 4.933181 5.070988
#> [8,] 4.535123 4.366512
#> [9,] 4.000571 4.172068
#> [10,] 3.898915 3.580247
#> [11,] 4.376927 4.062500
#> [12,] 3.751571 3.703704
#> [13,] 4.150771 4.017747
#> [14,] 4.493432 4.972222
#> [15,] 3.972016 3.513117
#> [16,] 4.527698 4.382716
#> AACTCTTCAAGGTTTC-400.2.2 AACTCTTGTGTGAATA-400.2.2
#> [1,] 4.292419 4.459459
#> [2,] 4.318592 4.310811
#> [3,] 4.255415 4.137592
#> [4,] 4.674188 4.534398
#> [5,] 4.277076 4.904177
#> [6,] 4.394404 4.595823
#> [7,] 4.688628 4.160934
#> [8,] 5.058664 4.987715
#> [9,] 4.342960 4.760442
#> [10,] 4.524368 4.232187
#> [11,] 4.907942 4.428747
#> [12,] 4.521661 4.495086
#> [13,] 4.456679 4.732187
#> [14,] 4.360108 4.070025
#> [15,] 4.206679 3.974201
#> [16,] 4.485560 4.468059
#> AACTGGTCAAACCCAT-400.2.2 AACTGGTTCCCTGACT-400.2.2
#> [1,] 3.931652 4.655039
#> [2,] 4.296275 3.749723
#> [3,] 4.230273 4.031561
#> [4,] 4.012614 4.244740
#> [5,] 5.097683 4.672757
#> [6,] 4.133177 4.181063
#> [7,] 4.982106 4.672757
#> [8,] 4.326195 4.347730
#> [9,] 4.212966 4.190476
#> [10,] 4.107070 3.759136
#> [11,] 4.212086 4.364341
#> [12,] 4.100029 4.148948
#> [13,] 4.225286 4.199889
#> [14,] 4.647991 4.343300
#> [15,] 3.882957 3.704319
#> [16,] 4.296568 4.240864
#> AAGGAGCCACATGACT-400.2.2 AAGGCAGAGACTGTAA-400.2.2
#> [1,] 5.023720 4.646621
#> [2,] 4.263421 3.651203
#> [3,] 4.240949 4.073310
#> [4,] 4.238452 4.421535
#> [5,] 4.767790 4.730241
#> [6,] 4.258427 3.811569
#> [7,] 4.112360 4.565292
#> [8,] 4.754057 4.442726
#> [9,] 5.129838 4.328751
#> [10,] 4.072409 3.865979
#> [11,] 4.133583 4.061856
#> [12,] 4.525593 3.979381
#> [13,] 4.938826 4.236541
#> [14,] 4.468165 4.380871
#> [15,] 3.750312 3.890607
#> [16,] 4.629213 3.922108
#> AAGGCAGGTCTCTCGT-400.2.2 AAGGCAGGTTAAGAAC-400.2.2
#> [1,] 4.409091 4.728896
#> [2,] 3.549296 3.519481
#> [3,] 3.953905 3.898539
#> [4,] 4.289373 4.449675
#> [5,] 4.923816 5.179383
#> [6,] 3.791293 3.949675
#> [7,] 4.809859 4.592532
#> [8,] 4.158771 4.321429
#> [9,] 4.108835 4.067370
#> [10,] 3.771447 3.748377
#> [11,] 3.927657 3.642045
#> [12,] 4.273367 3.909903
#> [13,] 4.133163 4.506494
#> [14,] 4.340589 4.250812
#> [15,] 4.185659 3.854708
#> [16,] 3.728553 3.905844
#> AAGGCAGTCGCAAGCC-400.2.2 AAGGTTCAGTCTTGCA-400.2.2
#> [1,] 4.580938 4.630658
#> [2,] 3.891578 4.258230
#> [3,] 4.075643 4.210905
#> [4,] 4.120524 4.247942
#> [5,] 4.725164 4.481481
#> [6,] 4.171962 4.217078
#> [7,] 4.257690 4.198560
#> [8,] 4.381241 4.699588
#> [9,] 4.348966 4.536008
#> [10,] 3.853757 4.465021
#> [11,] 4.245587 4.028807
#> [12,] 4.442259 4.407407
#> [13,] 4.581442 4.347737
#> [14,] 4.023701 3.965021
#> [15,] 3.860313 4.234568
#> [16,] 4.082199 4.663580
#> AAGGTTCCAGTGGGAT-400.2.2 AAGGTTCTCGTTTGCC-400.2.2
#> [1,] 4.315726 4.294355
#> [2,] 4.332533 4.309476
#> [3,] 4.321729 3.915323
#> [4,] 4.162065 4.363911
#> [5,] 4.506603 4.692540
#> [6,] 4.385354 4.378024
#> [7,] 4.715486 4.028226
#> [8,] 4.943577 4.464718
#> [9,] 4.803121 4.135081
#> [10,] 4.219688 4.509073
#> [11,] 4.074430 4.210685
#> [12,] 4.915966 4.213710
#> [13,] 4.327731 4.194556
#> [14,] 4.088836 4.278226
#> [15,] 4.039616 4.241935
#> [16,] 4.509004 4.143145
#> AAGTCTGCAATCGAAA-400.2.2 AAGTCTGCAGCCAATT-400.2.2
#> [1,] 4.452348 4.642675
#> [2,] 4.008978 4.039490
#> [3,] 4.162983 4.003185
#> [4,] 3.937845 4.340127
#> [5,] 4.560773 4.529299
#> [6,] 4.258978 4.361783
#> [7,] 4.455110 4.100637
#> [8,] 4.459254 4.506369
#> [9,] 4.303177 4.510191
#> [10,] 3.965470 4.062420
#> [11,] 4.620856 4.112739
#> [12,] 4.422652 4.089172
#> [13,] 4.287983 4.175796
#> [14,] 4.223757 4.328025
#> [15,] 3.958564 4.117197
#> [16,] 3.924724 4.100000
#> AAGTCTGGTTCCTCCA-400.2.2 AATCCAGCATTGAGCT-400.2.2
#> [1,] 4.411976 4.634669
#> [2,] 4.467066 3.803355
#> [3,] 4.215569 4.485555
#> [4,] 4.038323 4.034483
#> [5,] 4.689820 4.379310
#> [6,] 4.663473 4.406337
#> [7,] 4.398802 4.419385
#> [8,] 4.894611 4.323392
#> [9,] 4.500599 4.103448
#> [10,] 4.015569 4.193849
#> [11,] 4.298204 4.969245
#> [12,] 4.607186 4.671016
#> [13,] 4.076647 4.110904
#> [14,] 3.974850 3.970177
#> [15,] 4.217964 4.222740
#> [16,] 4.779641 4.431500
#> AATCGGTAGACTGTAA-400.2.2 AATCGGTCAAGGTTCT-400.2.2
#> [1,] 4.238994 4.554039
#> [2,] 4.119497 3.746725
#> [3,] 4.219078 3.901201
#> [4,] 4.192872 4.760371
#> [5,] 4.747379 4.878275
#> [6,] 4.327044 3.927948
#> [7,] 4.291405 4.627729
#> [8,] 4.631027 4.302948
#> [9,] 4.606918 3.989083
#> [10,] 4.121593 3.766921
#> [11,] 4.405660 4.123908
#> [12,] 4.376310 3.768013
#> [13,] 4.500000 4.131550
#> [14,] 4.132075 4.157205
#> [15,] 4.137317 3.829694
#> [16,] 4.698113 3.941048
#> ACACCAATCATACGGT-400.2.2 ACACCCTAGGAATTAC-400.2.2
#> [1,] 4.661389 4.224842
#> [2,] 3.512789 4.111158
#> [3,] 3.888348 4.084632
#> [4,] 4.597645 4.254316
#> [5,] 5.197320 5.117895
#> [6,] 3.963865 3.744842
#> [7,] 4.924076 4.933895
#> [8,] 4.155501 4.608000
#> [9,] 3.926106 4.144842
#> [10,] 3.851807 3.917053
#> [11,] 4.195290 4.289684
#> [12,] 4.033293 3.953263
#> [13,] 4.221275 4.133474
#> [14,] 4.189606 4.650947
#> [15,] 3.949249 3.877474
#> [16,] 4.070240 4.176000
#> ACACCCTCATATGAGA-400.2.2 ACACCCTCATCTCCCA-400.2.2
#> [1,] 4.129323 4.586489
#> [2,] 3.901504 4.183214
#> [3,] 3.784211 4.028659
#> [4,] 4.104511 4.533265
#> [5,] 5.444361 4.468782
#> [6,] 3.963158 4.619243
#> [7,] 5.215038 4.416581
#> [8,] 4.139850 5.195496
#> [9,] 3.971429 4.564995
#> [10,] 3.803759 4.670420
#> [11,] 4.263158 4.594678
#> [12,] 4.303759 4.378710
#> [13,] 4.278195 4.064483
#> [14,] 4.242857 3.866940
#> [15,] 3.803008 3.751279
#> [16,] 4.094737 4.277380
#> ACACCGGCACTCGACG-400.2.2 ACACTGAAGAGTCGGT-400.2.2
#> [1,] 4.508425 4.263241
#> [2,] 4.243956 3.911462
#> [3,] 4.212454 3.773123
#> [4,] 4.140659 4.219763
#> [5,] 4.391209 5.018182
#> [6,] 4.076190 4.184980
#> [7,] 4.358242 4.840316
#> [8,] 4.305495 4.589723
#> [9,] 4.251282 4.164427
#> [10,] 3.950916 3.903557
#> [11,] 4.302564 4.185771
#> [12,] 3.978022 3.880632
#> [13,] 4.328205 4.050593
#> [14,] 4.313553 4.182609
#> [15,] 3.863004 3.641107
#> [16,] 4.370696 3.891700
#> ACAGCTACACGGCTAC-400.2.2 ACCCACTTCAATACCG-400.2.2
#> [1,] 4.002092 4.431115
#> [2,] 3.955370 4.486410
#> [3,] 4.204324 4.132146
#> [4,] 4.097629 4.320525
#> [5,] 4.809623 4.652296
#> [6,] 4.069038 4.444236
#> [7,] 4.585077 4.577320
#> [8,] 4.311715 4.948454
#> [9,] 4.458856 4.729147
#> [10,] 4.070432 4.614808
#> [11,] 4.494421 4.608247
#> [12,] 4.421897 4.429241
#> [13,] 4.151325 4.121837
#> [14,] 4.415621 4.537957
#> [15,] 3.913529 4.104967
#> [16,] 4.458159 4.722587
#> ACCCACTTCGCGGATC-400.2.2 ACCGTAACAAACCCAT-400.2.2
#> [1,] 4.318244 4.490476
#> [2,] 4.212620 3.427619
#> [3,] 4.556927 3.931429
#> [4,] 4.163237 4.314286
#> [5,] 4.422497 5.264762
#> [6,] 4.021948 3.960952
#> [7,] 4.146776 4.805714
#> [8,] 4.617284 4.123810
#> [9,] 4.327846 4.710476
#> [10,] 4.458162 3.739048
#> [11,] 4.031550 3.793333
#> [12,] 4.400549 4.360000
#> [13,] 4.518519 4.273333
#> [14,] 4.049383 4.319048
#> [15,] 4.268861 3.780952
#> [16,] 4.722908 3.957143
#> ACCGTAACACGGTTTA-400.2.2 ACCGTAAGTAATCGTC-400.2.2
#> [1,] 4.584514 4.440871
#> [2,] 3.878187 3.618257
#> [3,] 3.973088 4.171680
#> [4,] 4.362606 4.028527
#> [5,] 4.659585 4.656120
#> [6,] 3.647309 3.942946
#> [7,] 4.934372 4.675311
#> [8,] 4.412181 4.359959
#> [9,] 4.217186 4.422199
#> [10,] 3.972144 3.603734
#> [11,] 3.929178 3.992739
#> [12,] 3.813975 4.270747
#> [13,] 3.969311 4.054461
#> [14,] 4.326251 4.150415
#> [15,] 3.801228 4.260373
#> [16,] 4.005194 4.107884
#> ACCGTAAGTATAATGG-400.2.2 ACCGTAATCATTGCCC-400.2.2
#> [1,] 4.315959 4.567951
#> [2,] 4.004505 4.237323
#> [3,] 4.584299 4.338742
#> [4,] 4.362291 4.265720
#> [5,] 4.759974 4.830291
#> [6,] 4.923423 4.639621
#> [7,] 4.249035 4.269101
#> [8,] 4.749678 5.067613
#> [9,] 4.665380 4.811359
#> [10,] 4.355212 4.466531
#> [11,] 4.745817 4.562542
#> [12,] 4.279923 4.404327
#> [13,] 4.082368 4.166329
#> [14,] 4.329472 4.315754
#> [15,] 4.258044 4.018932
#> [16,] 4.696911 4.663286
#> ACGAGCCTCCGTAGGC-400.2.2 ACGAGGAAGGGTCGAT-400.2.2
#> [1,] 4.148548 4.609756
#> [2,] 4.008103 3.926249
#> [3,] 4.253883 3.784553
#> [4,] 3.792032 4.067944
#> [5,] 4.390952 5.060395
#> [6,] 3.910196 4.066783
#> [7,] 4.101958 5.205575
#> [8,] 5.064146 4.307201
#> [9,] 4.752870 4.224739
#> [10,] 4.062795 3.986643
#> [11,] 4.326806 4.174797
#> [12,] 4.522620 4.044135
#> [13,] 4.721134 4.255517
#> [14,] 4.396354 4.329849
#> [15,] 3.910196 3.796748
#> [16,] 4.717083 4.199768
#> ACGATACGTGAGGGTT-400.2.2 ACGATGTAGATCCCAT-400.2.2
#> [1,] 4.443128 4.293869
#> [2,] 4.209716 4.501057
#> [3,] 4.325829 4.331924
#> [4,] 4.063981 4.319239
#> [5,] 4.292654 4.391121
#> [6,] 4.290284 4.790698
#> [7,] 4.477488 4.023256
#> [8,] 4.580569 5.189218
#> [9,] 4.764218 4.630021
#> [10,] 4.303318 4.548626
#> [11,] 4.392180 4.274841
#> [12,] 4.484597 4.464059
#> [13,] 4.542654 4.068710
#> [14,] 4.375592 4.508457
#> [15,] 4.180095 4.436575
#> [16,] 4.965640 4.453488
#> ACGATGTCATAAGACA-400.2.2 ACGCAGCAGGAGTAGA-400.2.2
#> [1,] 4.217631 4.438316
#> [2,] 3.530762 4.012337
#> [3,] 3.807163 3.910015
#> [4,] 4.224059 4.007257
#> [5,] 5.229568 4.710450
#> [6,] 4.056933 3.835269
#> [7,] 5.123967 4.379536
#> [8,] 4.175390 4.357039
#> [9,] 3.707071 4.415094
#> [10,] 3.984389 4.076197
#> [11,] 3.944904 4.012337
#> [12,] 3.794307 4.078374
#> [13,] 4.172635 4.588534
#> [14,] 4.231405 4.084180
#> [15,] 3.685950 3.925254
#> [16,] 3.752066 4.303338
#> ACGCCGATCCGTACAA-400.2.2 ACGGAGACATGGTCTA-400.2.2
#> [1,] 4.143665 4.190295
#> [2,] 4.125566 4.416746
#> [3,] 3.987557 4.125595
#> [4,] 4.314480 4.293054
#> [5,] 4.199095 4.674596
#> [6,] 4.212670 4.353949
#> [7,] 4.175339 4.374881
#> [8,] 4.483032 4.589914
#> [9,] 4.427602 4.719315
#> [10,] 4.489819 4.650809
#> [11,] 4.243213 4.420552
#> [12,] 4.321267 4.581351
#> [13,] 4.235294 4.525214
#> [14,] 4.116516 4.089439
#> [15,] 4.363122 4.037108
#> [16,] 4.420814 4.597526
#> ACGGAGATCTCCAACC-400.2.2 ACGGAGATCTTAACCT-400.2.2
#> [1,] 4.433277 4.740016
#> [2,] 4.313752 3.917776
#> [3,] 4.127334 4.081441
#> [4,] 4.419694 4.360219
#> [5,] 4.728014 4.803446
#> [6,] 4.325637 4.322631
#> [7,] 4.177250 4.404855
#> [8,] 4.728014 4.752545
#> [9,] 4.565365 4.139389
#> [10,] 4.292699 3.833986
#> [11,] 4.224788 4.310102
#> [12,] 4.420034 4.148786
#> [13,] 4.426146 4.394675
#> [14,] 4.183362 4.043853
#> [15,] 4.274024 4.130775
#> [16,] 4.487606 4.406421
#> ACGGCCATCACCCTCA-400.2.2 ACTATCTTCACAGTAC-400.2.2
#> [1,] 4.272530 4.887543
#> [2,] 4.199783 3.460208
#> [3,] 4.238328 3.741061
#> [4,] 4.042345 4.122261
#> [5,] 4.526602 5.709919
#> [6,] 4.293160 3.858708
#> [7,] 4.281216 5.058247
#> [8,] 4.631922 4.066897
#> [9,] 4.464169 4.058247
#> [10,] 4.139522 3.638985
#> [11,] 4.117807 4.038062
#> [12,] 4.635179 3.728950
#> [13,] 4.232899 4.181084
#> [14,] 3.957655 4.637255
#> [15,] 4.235071 4.143599
#> [16,] 4.579805 4.352941
#> ACTGAACGTCATACTG-400.2.2 ACTGAACGTCTGCCAG-400.2.2
#> [1,] 4.424939 4.654099
#> [2,] 4.170702 3.624177
#> [3,] 4.197337 4.150209
#> [4,] 4.329298 3.983244
#> [5,] 4.573850 5.473968
#> [6,] 3.694915 4.020946
#> [7,] 4.334140 5.216637
#> [8,] 4.794189 4.278875
#> [9,] 4.146489 4.098743
#> [10,] 3.789346 3.679234
#> [11,] 4.291768 4.247756
#> [12,] 4.164649 4.197487
#> [13,] 4.410412 4.034710
#> [14,] 4.341404 4.274087
#> [15,] 3.859564 3.890485
#> [16,] 4.455206 4.436266
#> ACTGAACGTTGGTAAA-400.2.2 ACTGAGTCATTCCTCG-400.2.2
#> [1,] 4.524496 4.749487
#> [2,] 4.100288 3.738193
#> [3,] 4.207493 4.276181
#> [4,] 4.354467 4.772074
#> [5,] 4.892795 4.604723
#> [6,] 4.957925 4.213552
#> [7,] 4.511816 4.151951
#> [8,] 4.558501 4.690965
#> [9,] 4.763689 4.529774
#> [10,] 4.427666 4.195072
#> [11,] 4.644957 4.194045
#> [12,] 4.402305 4.401437
#> [13,] 3.993084 4.144764
#> [14,] 4.474928 4.201232
#> [15,] 4.140058 3.953799
#> [16,] 4.331988 4.329569
#> ACTGTCCAGAGTACCG-400.2.2 ACTGTCCCATAGACTC-400.2.2
#> [1,] 4.172512 4.426760
#> [2,] 3.572196 3.754280
#> [3,] 3.833175 3.716867
#> [4,] 3.856872 4.010146
#> [5,] 5.426540 5.126823
#> [6,] 3.897946 4.015853
#> [7,] 5.248973 4.756183
#> [8,] 3.994313 4.422004
#> [9,] 4.046761 4.227647
#> [10,] 3.762717 3.870323
#> [11,] 4.078357 4.013633
#> [12,] 4.013270 4.046925
#> [13,] 4.328910 4.298668
#> [14,] 4.357030 4.131262
#> [15,] 3.782938 4.014902
#> [16,] 4.057504 4.007609
#> ACTGTCCTCGAACGGA-400.2.2 ACTTACTGTAAGCACG-400.2.2
#> [1,] 4.103730 4.340342
#> [2,] 3.761369 4.197109
#> [3,] 3.866633 4.161629
#> [4,] 4.079714 4.185283
#> [5,] 5.296372 4.544021
#> [6,] 4.015841 4.245729
#> [7,] 5.037302 4.540079
#> [8,] 4.264691 4.747700
#> [9,] 3.964742 4.328515
#> [10,] 4.003577 4.676741
#> [11,] 4.070005 4.441524
#> [12,] 3.876852 4.201051
#> [13,] 4.476239 4.703022
#> [14,] 4.209504 4.237845
#> [15,] 3.867144 4.094612
#> [16,] 4.370465 4.250986
#> ACTTGTTCAACTGCTA-400.2.2 ACTTGTTTCTGTTGAG-400.2.2
#> [1,] 4.179543 4.321637
#> [2,] 4.280740 4.457310
#> [3,] 4.146899 4.079532
#> [4,] 3.949946 4.073684
#> [5,] 4.862894 4.381287
#> [6,] 4.392818 4.550877
#> [7,] 4.282916 4.104094
#> [8,] 4.930359 4.888889
#> [9,] 4.375408 4.424561
#> [10,] 4.078346 4.552047
#> [11,] 4.241567 4.681871
#> [12,] 4.221980 4.646784
#> [13,] 4.546246 4.061988
#> [14,] 4.180631 4.015205
#> [15,] 4.204570 3.976608
#> [16,] 4.560392 4.244444
#> ACTTTCAGTGGGTATG-400.2.2 AGAGTGGGTTTCCACC-400.2.2
#> [1,] 4.177379 4.277965
#> [2,] 4.223717 4.132087
#> [3,] 4.161435 4.182348
#> [4,] 4.162431 4.074778
#> [5,] 4.579970 5.087956
#> [6,] 4.582461 4.114925
#> [7,] 4.185351 4.749617
#> [8,] 4.602392 4.224027
#> [9,] 4.614350 4.089795
#> [10,] 4.439960 3.969047
#> [11,] 4.344793 4.358566
#> [12,] 4.452417 4.363776
#> [13,] 4.331340 4.319032
#> [14,] 4.367215 4.377873
#> [15,] 4.180369 4.152620
#> [16,] 4.584454 4.441312
#> AGAGTGGTCATTATCC-400.2.2 AGCAGCCTCAACCAAC-400.2.2
#> [1,] 4.093444 4.366893
#> [2,] 3.718161 4.273959
#> [3,] 3.900528 4.109390
#> [4,] 3.845516 4.517909
#> [5,] 5.647325 4.238141
#> [6,] 3.913338 4.535334
#> [7,] 5.204220 4.586641
#> [8,] 3.943482 4.739593
#> [9,] 4.010550 4.212004
#> [10,] 3.779201 4.380445
#> [11,] 4.215524 4.373669
#> [12,] 3.846270 4.391094
#> [13,] 3.929917 4.490803
#> [14,] 4.262999 4.063892
#> [15,] 4.101733 4.338819
#> [16,] 4.384326 4.413359
#> AGCATACAGAGACTTA-400.2.2 AGCATACAGATGTGGC-400.2.2
#> [1,] 4.767254 4.168623
#> [2,] 4.507342 3.897545
#> [3,] 3.934655 3.938100
#> [4,] 4.211454 4.237994
#> [5,] 4.398678 5.675560
#> [6,] 4.605727 4.088581
#> [7,] 4.204112 5.193170
#> [8,] 4.736417 4.145144
#> [9,] 4.352423 3.878335
#> [10,] 4.786344 3.879402
#> [11,] 4.119677 3.998933
#> [12,] 4.264317 4.052295
#> [13,] 4.462555 4.208111
#> [14,] 4.263583 4.128068
#> [15,] 4.182085 4.026681
#> [16,] 4.436123 4.115261
#> AGCGGTCCACATGGGA-400.2.2 AGCGTATGTTCCGTCT-400.2.2
#> [1,] 4.373225 4.932394
#> [2,] 4.542934 3.538732
#> [3,] 4.335362 3.802817
#> [4,] 4.253550 3.907042
#> [5,] 4.602434 4.850704
#> [6,] 4.461799 3.945070
#> [7,] 4.237323 4.714085
#> [8,] 4.956728 4.345070
#> [9,] 4.935767 4.183803
#> [10,] 4.207573 3.459859
#> [11,] 4.389452 4.411268
#> [12,] 4.419202 4.353521
#> [13,] 4.225828 4.341549
#> [14,] 3.915483 3.801408
#> [15,] 4.011494 3.687324
#> [16,] 4.728871 4.166901
#> AGCTCCTGTCCGCTGA-400.2.2 AGCTCCTGTGATGTGG-400.2.2
#> [1,] 4.473112 4.233691
#> [2,] 3.611081 4.070190
#> [3,] 3.789245 4.478943
#> [4,] 4.391635 4.327002
#> [5,] 4.969039 4.720892
#> [6,] 3.913091 3.951280
#> [7,] 4.941336 4.667217
#> [8,] 4.152091 4.390586
#> [9,] 4.243346 3.887696
#> [10,] 3.762629 4.008258
#> [11,] 3.624661 4.158547
#> [12,] 4.032048 4.256813
#> [13,] 4.205323 4.208092
#> [14,] 4.474199 4.260941
#> [15,] 3.812059 3.944674
#> [16,] 4.102662 4.222956
#> AGCTCTCAGCATCATC-400.2.2 AGCTCTCTCTTAGAGC-400.2.2
#> [1,] 4.668317 4.722406
#> [2,] 4.226485 4.186385
#> [3,] 4.007426 4.330469
#> [4,] 4.349010 4.434898
#> [5,] 4.451733 5.171844
#> [6,] 5.080446 4.021811
#> [7,] 4.155941 4.843358
#> [8,] 5.011139 4.219432
#> [9,] 4.550743 4.159947
#> [10,] 4.075495 3.864508
#> [11,] 4.084158 4.206213
#> [12,] 4.376238 3.832783
#> [13,] 4.535891 4.279577
#> [14,] 4.658416 4.106411
#> [15,] 4.108911 3.883675
#> [16,] 4.304455 4.124917
#> AGCTTGAAGCTGTTCA-400.2.2 AGCTTGAGTAGGAGTC-400.2.2
#> [1,] 4.289786 4.603727
#> [2,] 4.384798 3.540373
#> [3,] 3.904988 4.007453
#> [4,] 4.142518 4.211180
#> [5,] 4.776722 5.018012
#> [6,] 4.547506 3.903727
#> [7,] 4.350356 5.298137
#> [8,] 4.878860 4.293168
#> [9,] 4.308789 4.055280
#> [10,] 4.267221 3.797516
#> [11,] 4.377672 4.373292
#> [12,] 4.519002 3.699379
#> [13,] 4.267221 4.390683
#> [14,] 3.819477 4.498137
#> [15,] 3.995249 3.675155
#> [16,] 4.395487 3.826087
#> AGGCCACAGTTTCCTT-400.2.2 AGGGAGTAGGGCTTCC-400.2.2
#> [1,] 4.511679 4.503110
#> [2,] 3.945985 4.295490
#> [3,] 4.031387 4.354588
#> [4,] 3.966423 4.204510
#> [5,] 5.328467 4.437014
#> [6,] 4.052555 4.734837
#> [7,] 4.796350 4.240280
#> [8,] 4.261314 4.679627
#> [9,] 3.921168 4.799378
#> [10,] 3.743066 4.508554
#> [11,] 4.391971 4.493779
#> [12,] 4.067153 4.431571
#> [13,] 4.432117 4.231726
#> [14,] 4.067883 4.195956
#> [15,] 4.051825 4.087092
#> [16,] 4.453285 4.131415
#> AGGGAGTAGTACCGGA-400.2.2 AGGGATGTCAGTACGT-400.2.2
#> [1,] 4.106809 4.366995
#> [2,] 4.698264 4.064039
#> [3,] 4.226969 3.936782
#> [4,] 4.025367 4.149425
#> [5,] 4.259012 4.962233
#> [6,] 4.004005 4.114122
#> [7,] 4.036048 4.383415
#> [8,] 4.722296 4.802956
#> [9,] 4.626168 4.256158
#> [10,] 4.540721 4.023810
#> [11,] 4.348465 3.954844
#> [12,] 4.284379 4.114943
#> [13,] 4.781041 4.615764
#> [14,] 4.213618 4.033662
#> [15,] 3.969292 4.105911
#> [16,] 4.724967 4.137110
#> AGGGTGAGTCAAACTC-400.2.2 AGGTCATGTCTAGGTT-400.2.2
#> [1,] 4.435208 4.302770
#> [2,] 4.429095 3.667622
#> [3,] 3.965770 3.855778
#> [4,] 4.270171 3.942693
#> [5,] 4.218826 5.011461
#> [6,] 3.891198 3.864374
#> [7,] 4.256724 4.972302
#> [8,] 4.798289 4.043935
#> [9,] 4.387531 4.146132
#> [10,] 4.233496 3.948424
#> [11,] 4.090465 4.335244
#> [12,] 4.391198 4.183381
#> [13,] 4.887531 4.375358
#> [14,] 4.088020 4.610315
#> [15,] 3.831296 3.600764
#> [16,] 4.375306 3.861509
#> AGGTCATTCGCCCTTA-400.2.2 AGGTCCGGTCCATCCT-400.2.2
#> [1,] 4.303933 4.019152
#> [2,] 4.528010 4.372093
#> [3,] 4.028605 4.212038
#> [4,] 4.147795 4.288646
#> [5,] 4.320620 4.658003
#> [6,] 4.027414 4.478796
#> [7,] 4.041716 4.162791
#> [8,] 5.156138 4.570451
#> [9,] 4.330155 4.480164
#> [10,] 4.106079 4.425445
#> [11,] 3.978546 4.259918
#> [12,] 3.995232 4.421341
#> [13,] 4.556615 4.511628
#> [14,] 4.077473 3.960328
#> [15,] 4.025030 3.874145
#> [16,] 4.194279 4.734610
#> AGTAGTCTCTACCTGC-400.2.2 AGTCTTTCAGTAAGAT-400.2.2
#> [1,] 4.361345 4.433426
#> [2,] 3.891379 4.312535
#> [3,] 4.094304 4.402228
#> [4,] 3.997510 4.416156
#> [5,] 5.280423 4.706407
#> [6,] 4.148148 4.245125
#> [7,] 5.050420 3.958774
#> [8,] 4.296608 4.935376
#> [9,] 4.222533 4.722563
#> [10,] 3.926860 4.212813
#> [11,] 4.220977 4.273538
#> [12,] 3.898537 4.588858
#> [13,] 4.221600 4.521448
#> [14,] 4.536259 4.269638
#> [15,] 3.804855 4.164903
#> [16,] 4.075319 4.363231
#> AGTCTTTTCCCTTGCA-400.2.2 AGTGGGAAGGGAACGG-400.2.2
#> [1,] 4.662610 4.484848
#> [2,] 3.625423 4.356749
#> [3,] 3.948614 3.899449
#> [4,] 4.205544 3.909091
#> [5,] 4.793103 4.232782
#> [6,] 3.847194 4.293388
#> [7,] 4.891819 4.377410
#> [8,] 4.218391 4.636364
#> [9,] 4.211629 4.396694
#> [10,] 4.010142 4.268595
#> [11,] 4.098715 4.104683
#> [12,] 4.217039 4.440771
#> [13,] 4.246112 4.618457
#> [14,] 4.508452 4.245179
#> [15,] 3.749155 3.976584
#> [16,] 3.883029 4.691460
#> AGTGGGATCGGCTACG-400.2.2 AGTTGGTAGGGAGTAA-400.2.2
#> [1,] 4.670543 4.203193
#> [2,] 3.565245 4.288099
#> [3,] 3.841085 4.448476
#> [4,] 4.269380 4.235123
#> [5,] 5.031654 4.694485
#> [6,] 3.945090 4.265602
#> [7,] 4.808140 4.278665
#> [8,] 4.217700 4.725689
#> [9,] 4.026486 4.672714
#> [10,] 3.666667 4.611756
#> [11,] 4.011628 4.412192
#> [12,] 3.897933 4.522496
#> [13,] 4.478036 4.195936
#> [14,] 4.162791 3.924528
#> [15,] 3.923773 4.478955
#> [16,] 4.293282 4.703193
#> AGTTGGTGTTTGTGTG-400.2.2 ATAACGCAGCAGGCTA-400.2.2
#> [1,] 4.207713 4.635234
#> [2,] 4.053462 3.854532
#> [3,] 4.466258 4.021199
#> [4,] 4.069238 4.447368
#> [5,] 4.471516 4.695906
#> [6,] 3.969325 3.793129
#> [7,] 4.434706 4.290205
#> [8,] 4.281332 4.779971
#> [9,] 4.156880 4.282164
#> [10,] 4.120947 3.941520
#> [11,] 4.362840 4.187135
#> [12,] 4.375986 4.098684
#> [13,] 3.923751 4.182018
#> [14,] 4.343558 4.107456
#> [15,] 4.103418 4.167398
#> [16,] 4.173532 4.189327
#> ATAACGCAGCGTGTCC-400.2.2 ATAACGCTCGTTGACA-400.2.2
#> [1,] 4.186640 4.669426
#> [2,] 4.122790 4.095475
#> [3,] 3.995088 4.160044
#> [4,] 4.113949 4.073400
#> [5,] 4.851670 5.043598
#> [6,] 4.451866 3.812362
#> [7,] 4.355599 4.647351
#> [8,] 4.540275 4.630795
#> [9,] 4.233792 4.275938
#> [10,] 4.214145 3.880795
#> [11,] 3.833988 4.337196
#> [12,] 4.225933 4.052980
#> [13,] 4.418468 4.092163
#> [14,] 3.986248 4.389073
#> [15,] 3.960707 4.076159
#> [16,] 4.712181 4.566225
#> ATAGACCAGCATCATC-400.2.2 ATCACGAAGAATGTGT-400.2.2
#> [1,] 4.637324 4.234894
#> [2,] 4.503521 4.336858
#> [3,] 4.019953 4.259063
#> [4,] 4.275822 4.255287
#> [5,] 4.408451 4.569486
#> [6,] 4.250000 4.338369
#> [7,] 4.228873 4.621601
#> [8,] 4.894366 4.776435
#> [9,] 4.286385 4.580816
#> [10,] 4.045775 4.267372
#> [11,] 4.330986 4.648792
#> [12,] 4.184272 4.624622
#> [13,] 4.164319 4.286254
#> [14,] 4.253521 4.619335
#> [15,] 4.059859 4.037764
#> [16,] 4.389671 4.490181
#> ATCATCTAGTACTTGC-400.2.2 ATCATCTCAAGTCTAC-400.2.2
#> [1,] 4.538905 3.801297
#> [2,] 3.800000 4.448959
#> [3,] 3.846686 3.806077
#> [4,] 4.274928 4.135541
#> [5,] 5.265706 4.779447
#> [6,] 4.018444 3.772277
#> [7,] 4.919885 4.973028
#> [8,] 4.361960 4.792762
#> [9,] 4.094524 4.099351
#> [10,] 3.927954 4.072721
#> [11,] 4.227666 4.712530
#> [12,] 4.021326 3.994879
#> [13,] 4.198847 4.188460
#> [14,] 4.194236 4.384090
#> [15,] 3.666859 3.530898
#> [16,] 3.882997 4.422328
#> ATCATCTTCTAACGGT-400.2.2 ATCATGGTCCGAATGT-400.2.2
#> [1,] 4.627335 4.826115
#> [2,] 4.057030 3.751969
#> [3,] 4.282203 3.950787
#> [4,] 4.073255 3.967848
#> [5,] 5.303835 4.539370
#> [6,] 3.941986 4.333990
#> [7,] 4.792527 4.484252
#> [8,] 4.281711 4.330052
#> [9,] 4.011799 4.267717
#> [10,] 3.876598 3.775591
#> [11,] 4.030482 4.548556
#> [12,] 4.257129 4.353675
#> [13,] 4.340708 4.159449
#> [14,] 4.527040 4.210630
#> [15,] 3.985251 3.971785
#> [16,] 4.351524 4.024934
#> ATCCACCTCTGAAAGA-400.2.2 ATCCGAATCATCTGCC-400.2.2
#> [1,] 4.425819 4.582560
#> [2,] 4.473988 4.133581
#> [3,] 4.137765 4.322202
#> [4,] 4.337187 4.448361
#> [5,] 4.418112 4.667904
#> [6,] 4.438343 3.985776
#> [7,] 4.406551 4.241806
#> [8,] 4.801541 4.782931
#> [9,] 4.719653 4.069264
#> [10,] 4.664740 4.132962
#> [11,] 4.100193 4.476190
#> [12,] 4.380539 4.032158
#> [13,] 4.372832 4.084725
#> [14,] 4.582852 4.158318
#> [15,] 4.389210 4.326531
#> [16,] 4.721580 4.346320
#> ATCGAGTAGATCGGGT-400.2.2 ATCGAGTGTACATGTC-400.2.2
#> [1,] 4.665214 4.221540
#> [2,] 3.526507 3.790179
#> [3,] 4.090051 3.866629
#> [4,] 4.103123 4.218192
#> [5,] 5.424110 4.798549
#> [6,] 3.729847 3.938616
#> [7,] 5.010893 5.003906
#> [8,] 4.306463 4.235491
#> [9,] 4.262890 4.034598
#> [10,] 3.753086 3.844308
#> [11,] 4.245461 3.968192
#> [12,] 3.907771 3.907366
#> [13,] 4.135076 4.086496
#> [14,] 4.029049 4.503906
#> [15,] 4.137981 3.896763
#> [16,] 4.394336 4.097098
#> ATCTACTAGAGGTTAT-400.2.2 ATCTACTCAATGCCAT-400.2.2
#> [1,] 4.726285 4.521251
#> [2,] 3.326575 4.959102
#> [3,] 3.728458 3.528468
#> [4,] 3.835626 4.400160
#> [5,] 5.559739 4.609463
#> [6,] 3.645185 4.801123
#> [7,] 5.130340 4.000802
#> [8,] 4.309196 4.905373
#> [9,] 4.180304 4.197273
#> [10,] 3.514120 5.065758
#> [11,] 3.928313 4.498797
#> [12,] 3.832006 4.491580
#> [13,] 4.119479 4.295108
#> [14,] 4.359160 4.102646
#> [15,] 4.013034 3.647153
#> [16,] 4.319334 4.259022
#> ATCTACTGTCCCTACT-400.2.2 ATCTGCCCATCACAAC-400.2.2
#> [1,] 4.693585 4.391762
#> [2,] 3.872279 4.382663
#> [3,] 3.928408 4.152778
#> [4,] 3.991409 4.288314
#> [5,] 5.277205 4.631705
#> [6,] 4.124284 4.481801
#> [7,] 4.971363 4.245690
#> [8,] 4.328179 5.022989
#> [9,] 4.063001 4.512452
#> [10,] 3.706758 4.328544
#> [11,] 3.986827 4.332375
#> [12,] 3.983963 4.528736
#> [13,] 4.372279 4.441092
#> [14,] 4.377434 4.087644
#> [15,] 4.084765 4.115900
#> [16,] 4.296105 4.458812
#> ATCTGCCTCAGCAACT-400.2.2 ATGAGGGGTTTGGCGC-400.2.2
#> [1,] 4.771032 4.615130
#> [2,] 3.959434 3.849798
#> [3,] 4.020419 4.161586
#> [4,] 4.357746 4.180316
#> [5,] 4.638443 4.878810
#> [6,] 3.853798 4.074550
#> [7,] 4.690716 4.212266
#> [8,] 4.325347 4.496144
#> [9,] 3.910700 4.062431
#> [10,] 3.832290 3.957767
#> [11,] 4.238225 4.313992
#> [12,] 4.009801 4.058391
#> [13,] 4.109175 4.003672
#> [14,] 4.304111 4.143224
#> [15,] 3.823850 4.393683
#> [16,] 4.132317 4.418656
#> ATGCGATAGTGTACGG-400.2.2 ATGCGATTCGCACTCT-400.2.2
#> [1,] 4.426174 4.417407
#> [2,] 3.714094 4.295737
#> [3,] 3.899329 4.261101
#> [4,] 3.867785 4.363233
#> [5,] 5.658389 4.388988
#> [6,] 3.901342 4.358792
#> [7,] 4.704027 4.217584
#> [8,] 4.210738 4.734458
#> [9,] 3.947651 4.744227
#> [10,] 3.936242 4.037300
#> [11,] 4.195973 4.225577
#> [12,] 4.183221 4.597691
#> [13,] 4.187248 4.670515
#> [14,] 4.107383 4.097691
#> [15,] 3.758389 4.383659
#> [16,] 4.743624 4.584369
#> ATGTGTGCACGCGAAA-400.2.2 ATTACTCAGTGACTCT-400.2.2
#> [1,] 4.497706 4.573689
#> [2,] 4.371560 4.378833
#> [3,] 4.232798 4.253215
#> [4,] 4.081422 4.292779
#> [5,] 4.646789 4.450049
#> [6,] 4.641055 4.594461
#> [7,] 4.267202 4.442136
#> [8,] 4.896789 5.046489
#> [9,] 4.909404 4.905045
#> [10,] 4.458716 4.466864
#> [11,] 4.496560 4.340257
#> [12,] 4.592890 4.451039
#> [13,] 4.680046 4.380811
#> [14,] 4.375000 4.541048
#> [15,] 3.740826 4.117705
#> [16,] 4.594037 4.868447
#> ATTATCCCAATGGACG-400.2.2 ATTATCCCAATTGCTG-400.2.2
#> [1,] 4.176380 4.475923
#> [2,] 4.383436 4.065811
#> [3,] 4.447853 4.104334
#> [4,] 4.685583 4.089888
#> [5,] 4.572086 4.795345
#> [6,] 4.236963 4.170947
#> [7,] 4.217025 4.355538
#> [8,] 4.848926 4.652488
#> [9,] 4.343558 4.238363
#> [10,] 4.420245 4.111557
#> [11,] 4.330521 4.456661
#> [12,] 4.176380 4.460674
#> [13,] 4.485429 3.986356
#> [14,] 4.055982 4.042536
#> [15,] 4.065184 4.144462
#> [16,] 4.467025 4.142055
#> ATTATCCCACTACAGT-400.2.2 ATTATCCGTCTAGTGT-400.2.2
#> [1,] 4.361046 4.242321
#> [2,] 3.516114 4.689420
#> [3,] 4.064456 3.886519
#> [4,] 4.537132 3.854949
#> [5,] 4.864549 5.057167
#> [6,] 3.997198 4.006826
#> [7,] 4.566091 3.888225
#> [8,] 4.409155 4.962457
#> [9,] 3.947688 4.361775
#> [10,] 3.817842 3.987201
#> [11,] 3.967772 4.343857
#> [12,] 4.055114 4.309727
#> [13,] 4.139187 4.575085
#> [14,] 4.037833 4.490614
#> [15,] 4.305932 3.726109
#> [16,] 4.351705 4.693686
#> ATTATCCGTTCTGTTT-400.2.2 ATTATCCTCGCGTAGC-400.2.2
#> [1,] 4.163399 4.457117
#> [2,] 4.450980 4.637774
#> [3,] 4.315593 4.258212
#> [4,] 4.267974 4.274635
#> [5,] 4.888889 4.792883
#> [6,] 4.168067 4.599453
#> [7,] 4.034547 4.453467
#> [8,] 4.630252 4.951642
#> [9,] 4.433240 4.745438
#> [10,] 4.134454 4.243613
#> [11,] 4.166200 4.352190
#> [12,] 4.290383 4.559307
#> [13,] 4.633053 4.604927
#> [14,] 4.126050 4.375912
#> [15,] 4.175537 4.136861
#> [16,] 4.431373 4.606752
#> ATTCTACTCTCAAACG-400.2.2 ATTGGACAGACACTAA-400.2.2
#> [1,] 4.305638 4.586667
#> [2,] 4.204748 4.174667
#> [3,] 4.118694 3.925333
#> [4,] 4.084075 3.989333
#> [5,] 4.463897 4.973333
#> [6,] 4.223541 4.040000
#> [7,] 4.174085 4.381333
#> [8,] 4.935707 4.881333
#> [9,] 4.496538 4.036000
#> [10,] 4.229476 4.100000
#> [11,] 4.356083 4.468000
#> [12,] 4.009891 4.024000
#> [13,] 4.784372 4.744000
#> [14,] 4.240356 4.288000
#> [15,] 4.193867 3.925333
#> [16,] 4.345203 3.969333
#> ATTGGACAGAGACTAT-400.2.2 ATTGGACCACGGATAG-400.2.2
#> [1,] 4.630816 4.760742
#> [2,] 3.699698 4.199219
#> [3,] 3.852568 4.369141
#> [4,] 4.183082 3.685547
#> [5,] 4.915408 4.676758
#> [6,] 3.959517 4.185547
#> [7,] 4.474320 4.414062
#> [8,] 4.447130 4.610352
#> [9,] 4.366163 4.285156
#> [10,] 3.819335 4.102539
#> [11,] 4.105136 4.322266
#> [12,] 4.395166 4.315430
#> [13,] 4.334139 4.391602
#> [14,] 4.282779 4.306641
#> [15,] 4.085196 4.609375
#> [16,] 3.908761 4.599609
#> ATTGGACGTACCAGTT-400.2.2 ATTGGACGTTATGTGC-400.2.2
#> [1,] 3.975578 4.185924
#> [2,] 4.178218 4.182773
#> [3,] 4.122112 4.061975
#> [4,] 4.093069 4.278361
#> [5,] 4.421122 4.399160
#> [6,] 4.172937 4.082983
#> [7,] 4.358416 4.584034
#> [8,] 4.640924 4.797269
#> [9,] 4.260726 4.672269
#> [10,] 4.012541 4.336134
#> [11,] 4.415182 4.451681
#> [12,] 4.428383 4.548319
#> [13,] 4.349835 4.961134
#> [14,] 4.295050 4.029412
#> [15,] 4.422442 4.387605
#> [16,] 4.720792 4.491597
#> ATTTCTGAGACAGGCT-400.2.2 ATTTCTGCAAAGGAAG-400.2.2
#> [1,] 4.188267 4.269615
#> [2,] 3.944065 4.303138
#> [3,] 3.946794 4.450785
#> [4,] 4.320600 4.073466
#> [5,] 5.031378 4.630528
#> [6,] 4.492497 3.956491
#> [7,] 4.436562 4.292439
#> [8,] 4.658936 4.960770
#> [9,] 4.451569 4.286020
#> [10,] 3.900409 4.177603
#> [11,] 3.701228 4.302425
#> [12,] 4.096862 3.972183
#> [13,] 4.221010 4.406562
#> [14,] 4.394270 4.315977
#> [15,] 3.776262 3.997860
#> [16,] 4.428377 4.635521
#> ATTTCTGGTCTAGTGT-400.2.2 CAACCAAAGGGAACGG-400.2.2
#> [1,] 4.491699 4.168151
#> [2,] 3.878033 3.977728
#> [3,] 4.233716 4.017817
#> [4,] 4.287356 4.464365
#> [5,] 4.948914 4.408686
#> [6,] 4.154534 4.134744
#> [7,] 4.946999 4.659243
#> [8,] 4.189655 4.275056
#> [9,] 4.026181 4.642539
#> [10,] 4.081737 4.318486
#> [11,] 4.141124 3.778396
#> [12,] 4.151341 4.505568
#> [13,] 4.402937 4.845212
#> [14,] 4.211367 4.253898
#> [15,] 3.805875 4.159243
#> [16,] 4.266284 4.378619
#> CAACCAAGTAAGGATT-400.2.2 CAACCAATCCGCATAA-400.2.2
#> [1,] 4.131679 4.499270
#> [2,] 4.066794 4.582482
#> [3,] 4.108142 4.345255
#> [4,] 4.194656 4.649635
#> [5,] 4.988550 4.545985
#> [6,] 4.017176 4.591971
#> [7,] 4.564885 4.665693
#> [8,] 4.262087 4.804380
#> [9,] 3.900763 4.590511
#> [10,] 3.954198 4.357664
#> [11,] 4.089059 4.379562
#> [12,] 3.798346 4.710949
#> [13,] 4.200382 4.396350
#> [14,] 4.146310 4.427007
#> [15,] 4.154580 4.663504
#> [16,] 4.495547 4.389051
#> CAACTAGAGATCCGAG-400.2.2 CAAGATCTCAGAGGTG-400.2.2
#> [1,] 5.291457 4.258641
#> [2,] 3.642658 4.058756
#> [3,] 4.094919 4.043779
#> [4,] 5.519821 4.014977
#> [5,] 4.675600 4.709677
#> [6,] 4.156337 4.342742
#> [7,] 3.714685 4.245968
#> [8,] 4.428811 4.814516
#> [9,] 3.853713 4.678571
#> [10,] 4.377443 4.275922
#> [11,] 4.326633 4.301267
#> [12,] 3.500838 4.269585
#> [13,] 3.804578 4.667627
#> [14,] 3.978783 4.300115
#> [15,] 4.647125 3.961406
#> [16,] 4.325516 4.432028
#> CAAGATCTCCACGACG-400.2.2 CAAGGCCTCCTGTACC-400.2.2
#> [1,] 4.155260 4.467836
#> [2,] 3.608636 4.309942
#> [3,] 3.815342 4.135478
#> [4,] 3.898484 4.384016
#> [5,] 5.548921 4.701754
#> [6,] 3.839688 4.192982
#> [7,] 5.439596 4.335283
#> [8,] 3.941663 4.937622
#> [9,] 3.964171 4.577973
#> [10,] 3.807993 4.066277
#> [11,] 4.072577 3.856725
#> [12,] 3.836472 4.108187
#> [13,] 4.194304 4.517544
#> [14,] 4.346808 3.900585
#> [15,] 3.583831 3.900585
#> [16,] 3.875517 4.221248
#> CAAGTTGGTACCGTTA-400.2.2 CAAGTTGGTCACTGGC-400.2.2
#> [1,] 4.799469 4.128719
#> [2,] 4.424967 4.354463
#> [3,] 4.084993 4.256792
#> [4,] 4.108898 4.104787
#> [5,] 5.039841 4.521345
#> [6,] 4.256308 4.309185
#> [7,] 4.268260 4.566624
#> [8,] 4.913679 4.730272
#> [9,] 5.095618 4.476714
#> [10,] 4.424967 4.317594
#> [11,] 4.134130 4.247736
#> [12,] 4.184595 4.364812
#> [13,] 4.354582 4.415265
#> [14,] 4.172643 4.226391
#> [15,] 3.832669 4.200517
#> [16,] 4.545817 4.524580
#> CAAGTTGGTGCAACTT-400.2.2 CAAGTTGTCCTGCTTG-400.2.2
#> [1,] 4.929401 4.323957
#> [2,] 3.811439 4.281280
#> [3,] 3.731903 3.981571
#> [4,] 4.419124 4.673133
#> [5,] 4.408400 4.190107
#> [6,] 3.713137 4.393792
#> [7,] 4.453083 4.506305
#> [8,] 4.504915 5.092144
#> [9,] 4.242181 4.746848
#> [10,] 3.744415 4.348206
#> [11,] 3.794459 4.552861
#> [12,] 4.078642 4.695441
#> [13,] 4.236819 4.330747
#> [14,] 4.344057 4.284190
#> [15,] 3.977659 4.404462
#> [16,] 4.018767 4.266731
#> CACACTCCAGGGTACA-400.2.2 CACACTCGTGTGACGA-400.2.2
#> [1,] 4.045367 4.423689
#> [2,] 4.504505 3.882257
#> [3,] 4.417954 4.261470
#> [4,] 4.276705 4.379213
#> [5,] 4.478121 5.009129
#> [6,] 4.552767 4.114466
#> [7,] 4.433398 4.490637
#> [8,] 4.689833 4.574438
#> [9,] 4.340412 4.091994
#> [10,] 4.241956 3.804073
#> [11,] 4.287967 4.164326
#> [12,] 4.177928 4.246021
#> [13,] 4.228121 4.152622
#> [14,] 4.128057 4.085440
#> [15,] 4.147362 4.223081
#> [16,] 4.412484 4.535112
#> CACAGGCAGTTGAGTA-400.2.2 CACAGGCCATAGTAAG-400.2.2
#> [1,] 4.202516 4.209540
#> [2,] 4.509434 4.657581
#> [3,] 4.101887 4.069847
#> [4,] 3.806289 3.923339
#> [5,] 4.638994 4.650767
#> [6,] 4.247799 4.430153
#> [7,] 4.319497 4.969336
#> [8,] 4.538365 4.726576
#> [9,] 4.388679 4.627768
#> [10,] 4.495597 4.637138
#> [11,] 4.267925 4.425043
#> [12,] 4.688050 4.844123
#> [13,] 4.381132 4.013629
#> [14,] 4.220126 4.102215
#> [15,] 4.272956 4.448041
#> [16,] 4.539623 4.233390
#> CACAGGCTCCGCGTTT-400.2.2 CACAGTAGTCCCTACT-400.2.2
#> [1,] 4.441637 4.745791
#> [2,] 4.145608 3.404040
#> [3,] 4.259928 3.915264
#> [4,] 4.090253 4.295735
#> [5,] 4.490975 5.245230
#> [6,] 4.268351 3.825477
#> [7,] 4.229844 5.194164
#> [8,] 5.078219 4.106061
#> [9,] 4.624549 4.196409
#> [10,] 4.305656 3.673962
#> [11,] 4.504212 4.104377
#> [12,] 4.771360 4.085859
#> [13,] 4.606498 4.378227
#> [14,] 4.203369 4.303591
#> [15,] 4.096270 3.940516
#> [16,] 4.716005 4.048260
#> CACAGTATCTCGTTTA-400.2.2 CACATAGAGGCTAGAC-400.2.2
#> [1,] 4.465517 4.277329
#> [2,] 3.720508 4.402788
#> [3,] 4.027223 4.452678
#> [4,] 4.143376 4.094644
#> [5,] 4.799456 4.423331
#> [6,] 4.283122 4.426999
#> [7,] 4.727768 3.920763
#> [8,] 4.405626 5.316948
#> [9,] 4.252269 4.845194
#> [10,] 3.887477 4.158474
#> [11,] 4.092559 4.346295
#> [12,] 4.072595 4.446809
#> [13,] 4.275862 4.429934
#> [14,] 4.190563 4.300073
#> [15,] 3.837568 4.454879
#> [16,] 4.373866 4.728540
#> CACATAGGTTTAAGCC-400.2.2 CACATTTAGCTCAACT-400.2.2
#> [1,] 4.563444 4.517949
#> [2,] 3.585347 4.194231
#> [3,] 4.012085 4.162179
#> [4,] 3.901813 4.232051
#> [5,] 4.961480 4.986538
#> [6,] 3.888218 4.164744
#> [7,] 4.954683 4.268590
#> [8,] 4.168429 4.726923
#> [9,] 4.125378 4.309615
#> [10,] 3.681269 3.976923
#> [11,] 4.215257 4.074359
#> [12,] 4.136707 4.337179
#> [13,] 4.255287 4.288462
#> [14,] 4.328550 4.024359
#> [15,] 3.509819 4.080769
#> [16,] 3.942598 4.446795
#> CACATTTGTGGTACAG-400.2.2 CACATTTTCTCAAGTG-400.2.2
#> [1,] 4.175433 4.450352
#> [2,] 3.987624 4.180610
#> [3,] 3.885829 4.333073
#> [4,] 4.067450 4.347928
#> [5,] 5.258045 4.860829
#> [6,] 3.855817 4.023456
#> [7,] 5.255260 4.466771
#> [8,] 4.650990 4.591869
#> [9,] 3.991955 4.444097
#> [10,] 3.902228 3.939015
#> [11,] 4.021658 4.150117
#> [12,] 4.099938 3.978890
#> [13,] 4.068069 4.467553
#> [14,] 4.186262 4.167318
#> [15,] 3.753094 3.957780
#> [16,] 4.014233 4.222830
#> CACCACTAGCCCTAAT-400.2.2 CACCACTAGCGATGAC-400.2.2
#> [1,] 4.530566 4.374880
#> [2,] 3.726304 4.224353
#> [3,] 4.172743 4.205177
#> [4,] 3.918116 4.215724
#> [5,] 4.766125 4.546500
#> [6,] 4.081324 4.096836
#> [7,] 4.800337 4.417066
#> [8,] 4.353898 4.817833
#> [9,] 4.344924 4.587728
#> [10,] 3.697140 4.246405
#> [11,] 4.303421 4.436242
#> [12,] 4.126753 4.713327
#> [13,] 4.358946 4.384468
#> [14,] 4.163769 4.136146
#> [15,] 3.821649 4.632790
#> [16,] 4.284913 4.614573
#> CACCACTTCGTAGGTT-400.2.2 CACCAGGCAACGATCT-400.2.2
#> [1,] 4.412058 4.036910
#> [2,] 4.240254 4.088859
#> [3,] 4.094742 4.694463
#> [4,] 3.948776 4.179768
#> [5,] 4.843608 4.708817
#> [6,] 3.858568 4.529733
#> [7,] 4.468722 4.198223
#> [8,] 4.742520 4.666439
#> [9,] 4.235721 4.268626
#> [10,] 3.963735 4.252221
#> [11,] 4.187670 4.429255
#> [12,] 4.174524 4.348599
#> [13,] 4.175431 4.098428
#> [14,] 4.756573 4.194805
#> [15,] 3.873527 4.347232
#> [16,] 4.031732 4.215311
#> CACCAGGTCTGCTTGC-400.2.2 CACCTTGCATTGCGGC-400.2.2
#> [1,] 4.390637 4.043262
#> [2,] 4.608596 3.800000
#> [3,] 4.586339 4.191489
#> [4,] 4.316193 3.904965
#> [5,] 5.131236 4.649645
#> [6,] 4.402149 4.210638
#> [7,] 4.257866 4.831206
#> [8,] 4.965464 4.355319
#> [9,] 4.632387 4.241135
#> [10,] 4.122026 3.998582
#> [11,] 4.254029 3.850355
#> [12,] 4.241750 4.058865
#> [13,] 4.277053 4.353901
#> [14,] 4.102840 4.199291
#> [15,] 4.202609 3.967376
#> [16,] 4.937068 4.539716
#> CACTCCACACGCTTTC-400.2.2 CAGATCAAGGAGCGTT-400.2.2
#> [1,] 4.228829 4.243272
#> [2,] 4.288293 4.238967
#> [3,] 4.326254 4.445640
#> [4,] 4.084417 3.996771
#> [5,] 4.774356 4.687836
#> [6,] 3.868596 3.759957
#> [7,] 4.698699 4.222820
#> [8,] 4.712769 4.684607
#> [9,] 4.306610 4.379978
#> [10,] 3.949562 4.350915
#> [11,] 4.519777 4.220667
#> [12,] 4.211309 4.722282
#> [13,] 4.060260 4.156082
#> [14,] 4.391027 3.698601
#> [15,] 4.015928 4.645856
#> [16,] 4.421556 4.433800
#> CAGATCATCGGTGTCG-400.2.2 CAGCAGCTCTTTAGTC-400.2.2
#> [1,] 4.221724 4.548753
#> [2,] 4.219928 3.900227
#> [3,] 4.383303 3.914399
#> [4,] 4.633752 4.375850
#> [5,] 4.464093 5.076531
#> [6,] 4.481149 3.996032
#> [7,] 4.506284 4.594671
#> [8,] 4.631957 4.602608
#> [9,] 4.525135 4.047619
#> [10,] 4.491921 3.945578
#> [11,] 4.620287 4.022109
#> [12,] 4.678636 4.001134
#> [13,] 4.606822 4.371882
#> [14,] 4.474865 4.195578
#> [15,] 4.386894 4.187075
#> [16,] 4.189408 4.095805
#> CAGCATAGTCCAACTA-400.2.2 CAGCATATCAAACCGT-400.2.2
#> [1,] 4.169963 4.645725
#> [2,] 4.019778 4.046632
#> [3,] 4.419036 4.168394
#> [4,] 4.215698 4.250000
#> [5,] 4.840544 5.094560
#> [6,] 5.059333 4.059585
#> [7,] 4.614957 4.516839
#> [8,] 4.614339 4.457254
#> [9,] 4.922744 4.113342
#> [10,] 4.393696 4.321891
#> [11,] 4.705192 4.066710
#> [12,] 4.273177 3.983808
#> [13,] 4.006799 4.218264
#> [14,] 4.499382 4.374352
#> [15,] 4.012979 4.091969
#> [16,] 4.446230 4.367228
#> CAGCATATCGTTTGCC-400.2.2 CAGCCGACACCATGTA-400.2.2
#> [1,] 4.402918 4.582036
#> [2,] 4.056117 4.206587
#> [3,] 4.207632 4.128144
#> [4,] 4.219978 4.520958
#> [5,] 4.638608 4.657485
#> [6,] 4.108866 3.994611
#> [7,] 4.442200 4.392814
#> [8,] 3.973064 4.508982
#> [9,] 4.049383 4.195210
#> [10,] 4.040404 4.084431
#> [11,] 4.346801 3.984431
#> [12,] 4.001122 4.135928
#> [13,] 4.437710 4.169461
#> [14,] 4.268238 4.085629
#> [15,] 3.983165 4.167665
#> [16,] 4.463524 4.309581
#> CAGCCGACAGACAGGT-400.2.2 CAGCCGACAGCTGTTA-400.2.2
#> [1,] 4.591310 4.431250
#> [2,] 3.906171 3.951562
#> [3,] 4.383501 4.039063
#> [4,] 4.467884 4.134375
#> [5,] 5.057305 4.646094
#> [6,] 4.098237 3.967969
#> [7,] 4.772670 4.712500
#> [8,] 4.405542 4.371094
#> [9,] 4.195844 4.288281
#> [10,] 3.960327 3.925781
#> [11,] 3.938287 4.253906
#> [12,] 4.231108 4.177344
#> [13,] 4.280856 4.317188
#> [14,] 4.374685 4.612500
#> [15,] 3.738035 3.989844
#> [16,] 3.995592 4.081250
#> CAGCCGACATGAGCGA-400.2.2 CAGCCGAGTAGGAGTC-400.2.2
#> [1,] 4.462905 4.181263
#> [2,] 4.234065 4.498473
#> [3,] 4.378265 4.336049
#> [4,] 4.373041 4.298880
#> [5,] 4.628004 4.421589
#> [6,] 4.598746 4.545316
#> [7,] 4.464995 4.560591
#> [8,] 4.758621 4.626782
#> [9,] 4.569488 4.338595
#> [10,] 4.240334 4.353360
#> [11,] 4.493208 4.157332
#> [12,] 4.451411 4.468432
#> [13,] 4.391850 4.655804
#> [14,] 4.127482 4.015275
#> [15,] 4.182863 4.225051
#> [16,] 4.375131 4.391039
#> CAGCGACAGAAACCTA-400.2.2 CAGCGACAGACAATAC-400.2.2
#> [1,] 4.323446 4.581818
#> [2,] 3.844837 3.847552
#> [3,] 4.038220 4.057343
#> [4,] 4.167712 4.330769
#> [5,] 4.836281 4.951049
#> [6,] 4.126640 3.889510
#> [7,] 4.744438 4.372727
#> [8,] 4.155163 4.510490
#> [9,] 4.254991 3.935664
#> [10,] 3.862521 3.997203
#> [11,] 4.280091 3.976224
#> [12,] 4.055334 4.349650
#> [13,] 3.976041 4.092308
#> [14,] 4.028523 3.974126
#> [15,] 3.601825 4.095105
#> [16,] 4.199087 3.932168
#> CAGCTGGGTGAGGCTA-400.2.2 CAGGTGCAGCCACGCT-400.2.2
#> [1,] 4.400609 4.168011
#> [2,] 4.358012 4.243280
#> [3,] 4.034483 4.481183
#> [4,] 4.283976 4.306452
#> [5,] 4.300203 4.310484
#> [6,] 4.287018 4.392473
#> [7,] 4.425963 4.288978
#> [8,] 4.891481 4.680108
#> [9,] 4.512170 4.466398
#> [10,] 4.322515 4.125000
#> [11,] 4.472617 4.227151
#> [12,] 4.337728 4.500000
#> [13,] 4.016227 4.465054
#> [14,] 4.515213 4.239247
#> [15,] 4.122718 4.108871
#> [16,] 4.698783 4.581989
#> CAGTAACGTTGGTAAA-400.2.2 CAGTAACTCGCAAACT-400.2.2
#> [1,] 4.312938 4.238095
#> [2,] 4.042868 4.373134
#> [3,] 4.231489 4.260128
#> [4,] 4.213562 4.084577
#> [5,] 5.048324 4.336176
#> [6,] 3.924396 4.228145
#> [7,] 4.666407 4.326226
#> [8,] 4.590413 4.869936
#> [9,] 4.237334 4.410803
#> [10,] 3.894388 4.230988
#> [11,] 4.328137 4.200426
#> [12,] 4.252143 4.251599
#> [13,] 4.197973 4.434257
#> [14,] 4.434139 4.002843
#> [15,] 4.281372 4.031983
#> [16,] 4.273188 4.344705
#> CAGTCCTCACGGCGTT-400.2.2 CAGTCCTCATACTACG-400.2.2
#> [1,] 4.308365 4.374220
#> [2,] 4.197253 4.316008
#> [3,] 4.129838 4.588358
#> [4,] 3.845194 4.566528
#> [5,] 4.525593 4.179834
#> [6,] 4.262172 4.362786
#> [7,] 4.197253 4.034304
#> [8,] 4.764045 4.555094
#> [9,] 4.569288 4.449064
#> [10,] 4.329588 4.468815
#> [11,] 4.084894 4.458420
#> [12,] 4.255930 4.666320
#> [13,] 4.546816 4.234927
#> [14,] 4.182272 4.152807
#> [15,] 4.044944 4.348233
#> [16,] 4.951311 4.546778
#> CATATGGTCCTTTCTC-400.2.2 CATCAAGAGTTAGCGG-400.2.2
#> [1,] 4.519020 4.643303
#> [2,] 3.556415 3.946565
#> [3,] 4.002579 4.049965
#> [4,] 4.282398 3.937543
#> [5,] 4.541586 5.031922
#> [6,] 4.112186 3.961832
#> [7,] 4.929723 4.601666
#> [8,] 4.162476 4.312283
#> [9,] 4.373308 4.201249
#> [10,] 3.617666 4.058293
#> [11,] 3.964539 3.794587
#> [12,] 4.233398 4.339348
#> [13,] 3.958736 4.388619
#> [14,] 4.363636 4.094379
#> [15,] 4.348807 4.596114
#> [16,] 4.191489 4.219292
#> CATCAAGGTGCCTGCA-400.2.2 CATCAAGGTTATCCGA-400.2.2
#> [1,] 4.065375 4.684994
#> [2,] 4.140436 4.530355
#> [3,] 4.066586 4.375716
#> [4,] 4.248184 4.084765
#> [5,] 4.521792 4.695304
#> [6,] 4.271186 4.443299
#> [7,] 4.221550 4.313860
#> [8,] 4.750605 4.776632
#> [9,] 4.733656 4.384880
#> [10,] 4.336562 4.572738
#> [11,] 4.223971 3.998855
#> [12,] 4.700969 4.558992
#> [13,] 4.503632 4.112257
#> [14,] 3.865617 4.293242
#> [15,] 3.985472 4.421535
#> [16,] 4.636804 4.159221
#> CATCAAGTCTACTATC-400.2.2 CATCAAGTCTGTGCAA-400.2.2
#> [1,] 4.421389 4.370123
#> [2,] 4.393456 4.147157
#> [3,] 4.272945 4.305463
#> [4,] 4.495611 4.290970
#> [5,] 4.690343 4.722408
#> [6,] 4.765363 4.268673
#> [7,] 4.411014 4.193980
#> [8,] 4.762171 4.785953
#> [9,] 4.501197 4.882943
#> [10,] 4.250599 4.180602
#> [11,] 4.508380 4.507246
#> [12,] 4.632083 4.176143
#> [13,] 4.241022 4.544036
#> [14,] 4.452514 4.098105
#> [15,] 4.249800 3.915273
#> [16,] 4.256185 4.539576
#> CATCAGAAGCAGCCTC-400.2.2 CATCAGAAGGATGCGT-400.2.2
#> [1,] 4.346120 4.671659
#> [2,] 4.202267 3.868088
#> [3,] 4.020052 3.940668
#> [4,] 4.340889 4.324309
#> [5,] 4.496949 4.684332
#> [6,] 4.175240 3.906106
#> [7,] 4.294682 4.396313
#> [8,] 4.879686 4.556452
#> [9,] 4.204882 4.349654
#> [10,] 4.376635 3.862327
#> [11,] 3.838710 3.843318
#> [12,] 4.430689 4.148041
#> [13,] 4.446382 4.187788
#> [14,] 4.037489 4.348502
#> [15,] 4.039233 3.979839
#> [16,] 4.762860 4.009793
#> CATCCACCAGTAAGCG-400.2.2 CATCGAAAGGACTGGT-400.2.2
#> [1,] 4.121854 4.475398
#> [2,] 4.458278 4.123010
#> [3,] 4.219868 4.335745
#> [4,] 4.304636 4.161360
#> [5,] 4.582781 5.185962
#> [6,] 4.015894 4.557887
#> [7,] 3.950993 4.009407
#> [8,] 4.605298 4.861795
#> [9,] 4.152318 4.563676
#> [10,] 4.325828 4.211288
#> [11,] 3.919205 4.255427
#> [12,] 4.925828 4.243849
#> [13,] 4.445033 4.204052
#> [14,] 4.207947 4.136035
#> [15,] 4.292715 4.320550
#> [16,] 4.807947 4.649783
#> CATCGGGGTCCGAACC-400.2.2 CATCGGGTCAACCAAC-400.2.2
#> [1,] 4.332491 4.280220
#> [2,] 4.352718 3.912088
#> [3,] 4.307206 3.976923
#> [4,] 4.314791 4.057143
#> [5,] 4.474083 5.016484
#> [6,] 4.166877 4.548352
#> [7,] 4.001264 4.679121
#> [8,] 4.489254 4.075824
#> [9,] 4.533502 4.013187
#> [10,] 4.232617 4.308791
#> [11,] 3.984829 4.357143
#> [12,] 4.681416 4.092308
#> [13,] 4.625790 4.140659
#> [14,] 4.077118 4.048352
#> [15,] 4.228824 3.976923
#> [16,] 4.807838 4.227473
#> CATGCCTAGTAAGTAC-400.2.2 CATGCCTCACTTCTGC-400.2.2
#> [1,] 4.499333 5.046653
#> [2,] 3.864000 3.540230
#> [3,] 3.902000 3.627451
#> [4,] 4.348000 4.346856
#> [5,] 4.864667 5.158215
#> [6,] 4.103333 3.844490
#> [7,] 4.218667 4.673428
#> [8,] 4.654000 4.261663
#> [9,] 4.205333 3.868154
#> [10,] 3.760667 3.592292
#> [11,] 4.091333 3.756592
#> [12,] 4.180667 3.801893
#> [13,] 4.417333 3.851251
#> [14,] 4.022000 4.342799
#> [15,] 3.898000 3.893847
#> [16,] 4.306667 4.082488
#> CATGGCGAGCGTTCCG-400.2.2 CATTATCCAATAGCAA-400.2.2
#> [1,] 4.458003 4.248017
#> [2,] 3.775595 4.087784
#> [3,] 3.993732 4.162348
#> [4,] 4.328040 4.454257
#> [5,] 5.020059 4.650978
#> [6,] 4.096949 4.062930
#> [7,] 5.085667 4.816499
#> [8,] 4.288341 4.492861
#> [9,] 4.107397 4.093601
#> [10,] 4.146260 3.988366
#> [11,] 4.221897 4.050767
#> [12,] 3.817802 3.754627
#> [13,] 4.243209 4.038604
#> [14,] 4.415796 4.002115
#> [15,] 3.973673 3.861978
#> [16,] 3.833264 4.415124
#> CCACCTAGTATATGGA-400.2.2 CCACGGATCTGTCAAG-400.2.2
#> [1,] 4.324405 4.718804
#> [2,] 4.300595 3.817136
#> [3,] 4.225198 4.032777
#> [4,] 4.255952 4.303048
#> [5,] 4.597222 5.165037
#> [6,] 4.234127 3.961472
#> [7,] 4.292659 4.853939
#> [8,] 4.490079 3.996550
#> [9,] 4.737103 4.063255
#> [10,] 4.572421 3.429557
#> [11,] 4.360119 4.007476
#> [12,] 4.388889 4.275446
#> [13,] 5.100198 4.205865
#> [14,] 4.051587 4.141461
#> [15,] 4.320437 3.855664
#> [16,] 4.516865 3.955722
#> CCAGCGACACGACTCG-400.2.2 CCAGCGACAGCATGAG-400.2.2
#> [1,] 4.852570 4.116183
#> [2,] 4.710960 4.162863
#> [3,] 4.297769 3.967842
#> [4,] 4.611057 4.227178
#> [5,] 4.703201 4.502075
#> [6,] 4.714840 4.256224
#> [7,] 4.341416 4.281120
#> [8,] 4.788555 4.570539
#> [9,] 4.383123 4.511411
#> [10,] 4.262852 4.013485
#> [11,] 4.435500 3.963693
#> [12,] 4.467507 4.028008
#> [13,] 4.527643 4.538382
#> [14,] 4.334627 4.223029
#> [15,] 4.351115 4.062241
#> [16,] 4.298739 4.311203
#> CCAGCGACAGCTTAAC-400.2.2 CCAGCGACATACCATG-400.2.2
#> [1,] 4.040865 4.104017
#> [2,] 3.961538 4.791543
#> [3,] 4.117788 3.997886
#> [4,] 4.058894 4.030021
#> [5,] 4.628606 4.571247
#> [6,] 4.278846 3.739535
#> [7,] 4.350962 4.356025
#> [8,] 4.646635 5.162368
#> [9,] 4.600962 4.180550
#> [10,] 4.308894 4.076110
#> [11,] 3.739183 4.523890
#> [12,] 4.353365 4.236364
#> [13,] 4.457933 4.090486
#> [14,] 4.209135 5.006765
#> [15,] 3.909856 3.764905
#> [16,] 4.085337 4.200423
#> CCATGTCGTTGCTCCT-400.2.2 CCATGTCTCCGCAAGC-400.2.2
#> [1,] 4.447531 4.282715
#> [2,] 4.381687 4.339437
#> [3,] 4.347737 4.401072
#> [4,] 4.340535 4.179544
#> [5,] 4.350823 4.502903
#> [6,] 4.226337 4.398839
#> [7,] 4.265432 4.250112
#> [8,] 5.126543 5.006699
#> [9,] 4.873457 4.870478
#> [10,] 4.281893 4.490397
#> [11,] 4.253086 4.292541
#> [12,] 4.385802 4.510942
#> [13,] 4.566872 4.523448
#> [14,] 3.986626 4.199643
#> [15,] 4.361111 4.033050
#> [16,] 4.453704 4.602054
#> CCATTCGAGCACCGTC-400.2.2 CCATTCGGTTTGGCGC-400.2.2
#> [1,] 4.390009 4.8600
#> [2,] 4.539001 3.9128
#> [3,] 4.518843 4.3216
#> [4,] 4.699387 4.1200
#> [5,] 4.362840 4.8136
#> [6,] 4.466258 3.9360
#> [7,] 4.422436 4.4192
#> [8,] 4.632778 4.5184
#> [9,] 4.457493 4.1512
#> [10,] 4.411919 3.9144
#> [11,] 4.359334 4.4272
#> [12,] 4.376862 4.0912
#> [13,] 4.435583 4.1416
#> [14,] 4.369851 4.2952
#> [15,] 4.376862 4.0408
#> [16,] 4.538124 4.9816
#> CCCAATCAGACACTAA-400.2.2 CCCAATCAGGCATTGG-400.2.2
#> [1,] 4.667011 4.433243
#> [2,] 3.536194 4.401907
#> [3,] 4.084281 4.153951
#> [4,] 4.402792 4.423706
#> [5,] 4.854188 4.723433
#> [6,] 3.906412 4.145777
#> [7,] 4.671148 4.207084
#> [8,] 4.353154 4.775204
#> [9,] 3.976732 4.405995
#> [10,] 3.803516 4.216621
#> [11,] 3.804550 4.399183
#> [12,] 4.140124 4.440054
#> [13,] 4.210962 4.192098
#> [14,] 4.035677 4.239782
#> [15,] 4.306101 4.333787
#> [16,] 4.272492 4.275204
#> CCCAGTTCAGATAATG-400.2.2 CCCTCCTAGAGACTTA-400.2.2
#> [1,] 4.296422 4.394504
#> [2,] 4.324532 4.422964
#> [3,] 4.285349 4.469087
#> [4,] 4.313458 4.310108
#> [5,] 4.544293 5.013739
#> [6,] 4.479557 4.374877
#> [7,] 4.305792 4.358194
#> [8,] 4.804940 4.892051
#> [9,] 4.545145 4.900883
#> [10,] 4.559625 4.251227
#> [11,] 4.432709 4.384691
#> [12,] 4.429302 4.902846
#> [13,] 4.396082 4.370952
#> [14,] 4.382453 4.429833
#> [15,] 4.286201 3.930324
#> [16,] 4.451448 4.473994
#> CCCTCCTAGTGACATA-400.2.2 CCCTCCTGTGCAACTT-400.2.2
#> [1,] 4.325994 4.355355
#> [2,] 3.765625 4.031031
#> [3,] 3.956676 3.882883
#> [4,] 3.982244 4.072072
#> [5,] 5.222301 5.514515
#> [6,] 4.037642 3.716717
#> [7,] 5.193182 5.029029
#> [8,] 4.189631 4.699700
#> [9,] 4.348722 3.923924
#> [10,] 3.935369 3.615616
#> [11,] 4.067472 4.252252
#> [12,] 4.105824 3.879880
#> [13,] 4.201705 4.004004
#> [14,] 4.376420 4.670671
#> [15,] 3.928977 3.639640
#> [16,] 4.146307 4.309309
#> CCCTCCTTCAGGTAAA-400.2.2 CCGGGATTCCAGATCA-400.2.2
#> [1,] 4.421412 4.337992
#> [2,] 4.101367 4.285896
#> [3,] 4.225513 4.462516
#> [4,] 4.274487 4.467598
#> [5,] 4.779043 4.298602
#> [6,] 4.455581 4.505718
#> [7,] 4.189066 4.462516
#> [8,] 5.164009 4.952986
#> [9,] 4.719818 4.980940
#> [10,] 4.321185 4.499365
#> [11,] 4.439636 4.266836
#> [12,] 4.781321 4.177891
#> [13,] 4.856492 4.562897
#> [14,] 3.947608 4.663278
#> [15,] 4.175399 3.895807
#> [16,] 4.472665 4.551461
#> CCGGTAGAGCGATGAC-400.2.2 CCGGTAGAGCTAGTGG-400.2.2
#> [1,] 4.696721 4.444573
#> [2,] 4.362022 4.556582
#> [3,] 4.105191 3.825635
#> [4,] 4.127049 4.048499
#> [5,] 4.569672 4.476905
#> [6,] 4.453552 4.503464
#> [7,] 4.456284 4.272517
#> [8,] 4.853825 4.625866
#> [9,] 4.747268 4.376443
#> [10,] 4.342896 5.031178
#> [11,] 4.301913 4.602771
#> [12,] 4.323770 4.419169
#> [13,] 4.621585 4.272517
#> [14,] 4.513661 4.151270
#> [15,] 4.277322 3.927252
#> [16,] 4.695355 4.295612
#> CCGGTAGCAAAGTGCG-400.2.2 CCGGTAGTCTGCTTGC-400.2.2
#> [1,] 4.251168 4.182921
#> [2,] 4.445093 3.813542
#> [3,] 4.286215 3.870642
#> [4,] 4.114486 4.411824
#> [5,] 4.457944 5.000505
#> [6,] 4.282710 3.846387
#> [7,] 4.396028 5.102577
#> [8,] 4.626168 4.334512
#> [9,] 4.363318 4.185953
#> [10,] 4.224299 3.897423
#> [11,] 4.695093 4.117736
#> [12,] 4.712617 3.760990
#> [13,] 4.422897 4.193532
#> [14,] 4.023364 4.356241
#> [15,] 4.260514 3.701870
#> [16,] 4.463785 4.068216
#> CCGTACTTCCAAGCCG-400.2.2 CCGTGGAAGGTGTGGT-400.2.2
#> [1,] 4.623782 4.375819
#> [2,] 4.271605 3.890022
#> [3,] 4.361923 4.211945
#> [4,] 3.952567 4.284778
#> [5,] 5.348278 5.179170
#> [6,] 5.048083 3.785870
#> [7,] 4.543210 4.586307
#> [8,] 4.616634 4.221413
#> [9,] 4.423002 3.875455
#> [10,] 4.537362 3.814275
#> [11,] 4.579597 3.808449
#> [12,] 4.505523 3.928623
#> [13,] 3.947368 4.220685
#> [14,] 4.169591 3.962127
#> [15,] 4.437947 3.882010
#> [16,] 4.444444 4.250546
#> CCGTGGACACATTAGC-400.2.2 CCGTGGAGTAGCTGCC-400.2.2
#> [1,] 4.130263 4.248737
#> [2,] 4.860526 4.310606
#> [3,] 4.180263 4.190657
#> [4,] 4.246053 4.042929
#> [5,] 4.465789 4.866162
#> [6,] 4.040789 3.864899
#> [7,] 4.059211 4.083333
#> [8,] 5.342105 5.262626
#> [9,] 4.352632 4.056818
#> [10,] 4.101316 4.372475
#> [11,] 4.488158 4.487374
#> [12,] 4.265789 3.693182
#> [13,] 4.514474 4.279040
#> [14,] 4.272368 4.575758
#> [15,] 4.288158 3.460859
#> [16,] 4.460526 4.145202
#> CCGTGGAGTCCAGTTA-400.2.2 CCGTTCACAGACAAGC-400.2.2
#> [1,] 4.729390 4.087060
#> [2,] 3.724355 4.550388
#> [3,] 4.202643 4.163387
#> [4,] 4.273757 4.115981
#> [5,] 4.467590 4.733154
#> [6,] 4.093770 4.114192
#> [7,] 4.456891 4.656530
#> [8,] 4.405286 4.826774
#> [9,] 4.105098 4.275194
#> [10,] 3.808055 4.062016
#> [11,] 4.429830 4.503876
#> [12,] 4.380743 4.134168
#> [13,] 4.225928 4.112105
#> [14,] 3.988672 4.474061
#> [15,] 4.054122 3.903399
#> [16,] 4.072373 4.186643
#> CCGTTCAGTGCAGGTA-400.2.2 CCGTTCATCGCTAGCG-400.2.2
#> [1,] 4.152298 4.713339
#> [2,] 3.870559 3.633803
#> [3,] 3.968944 3.937862
#> [4,] 4.174161 4.225352
#> [5,] 5.411429 4.796189
#> [6,] 3.925466 4.049710
#> [7,] 5.148820 4.477216
#> [8,] 4.267578 4.420878
#> [9,] 3.961491 4.347142
#> [10,] 3.928944 3.874068
#> [11,] 4.235776 3.927920
#> [12,] 3.869814 4.105220
#> [13,] 4.052671 4.369511
#> [14,] 4.530186 4.533554
#> [15,] 3.592795 3.909693
#> [16,] 3.926460 4.077879
#> CCTAAAGGTCGAGTTT-400.2.2 CCTAAAGTCAACCATG-400.2.2
#> [1,] 4.701393 4.605392
#> [2,] 3.369608 3.333946
#> [3,] 4.055740 3.692402
#> [4,] 3.871267 3.753676
#> [5,] 4.707366 5.786765
#> [6,] 3.607167 4.009804
#> [7,] 4.791639 5.469363
#> [8,] 3.964831 3.757353
#> [9,] 4.428003 3.679534
#> [10,] 3.881221 3.642157
#> [11,] 3.871931 4.280025
#> [12,] 4.356337 3.987132
#> [13,] 4.315196 4.431985
#> [14,] 4.587923 4.148897
#> [15,] 4.192435 3.348652
#> [16,] 4.193099 3.950368
#> CCTAAAGTCGACCAGC-400.2.2 CCTACACAGAAGGTGA-400.2.2
#> [1,] 4.452310 4.486392
#> [2,] 3.867741 4.493354
#> [3,] 4.094108 4.407911
#> [4,] 4.095379 4.179430
#> [5,] 5.289106 4.507595
#> [6,] 4.050869 4.456646
#> [7,] 5.090716 4.145886
#> [8,] 4.204748 4.725949
#> [9,] 3.874947 4.678165
#> [10,] 3.774057 4.341456
#> [11,] 4.099618 4.226899
#> [12,] 4.030097 4.410759
#> [13,] 4.133531 4.504747
#> [14,] 4.217041 4.223418
#> [15,] 3.643069 4.288608
#> [16,] 3.924544 4.560443
#> CCTACACAGACATAAC-400.2.2 CCTACACAGCGTTTAC-400.2.2
#> [1,] 4.392034 3.925214
#> [2,] 4.593291 4.820513
#> [3,] 4.114256 4.032051
#> [4,] 4.536688 3.883547
#> [5,] 4.733753 4.545940
#> [6,] 4.367925 3.932692
#> [7,] 4.328092 3.710470
#> [8,] 4.984277 5.354701
#> [9,] 4.727463 4.462607
#> [10,] 4.575472 4.200855
#> [11,] 4.462264 4.653846
#> [12,] 4.490566 3.927350
#> [13,] 4.551363 4.133547
#> [14,] 4.384696 4.651709
#> [15,] 4.143606 3.981838
#> [16,] 4.723270 4.400641
#> CCTACACCAAGTCTAC-400.2.2 CCTACACCACACAGAG-400.2.2
#> [1,] 4.232716 4.373068
#> [2,] 4.126515 3.676233
#> [3,] 4.404847 4.363503
#> [4,] 4.316821 4.144224
#> [5,] 4.945474 5.125828
#> [6,] 4.045617 4.018396
#> [7,] 4.700285 4.907285
#> [8,] 4.469351 4.133186
#> [9,] 4.225944 4.036792
#> [10,] 3.914825 4.018396
#> [11,] 4.171062 4.155261
#> [12,] 4.381682 3.947756
#> [13,] 4.323236 4.151582
#> [14,] 4.147897 4.303164
#> [15,] 4.250891 3.922001
#> [16,] 4.327156 4.273731
#> CCTACCATCACTGGGC-400.2.2 CCTATTAGTCCGAAGA-400.2.2
#> [1,] 4.611260 4.450266
#> [2,] 4.325737 4.373956
#> [3,] 3.753351 4.217920
#> [4,] 3.942359 4.290433
#> [5,] 4.836461 4.785118
#> [6,] 4.304290 4.322323
#> [7,] 4.596515 4.471526
#> [8,] 4.486595 4.498102
#> [9,] 4.343164 4.110099
#> [10,] 4.144772 4.413060
#> [11,] 4.474531 4.507973
#> [12,] 4.229223 4.278664
#> [13,] 4.741287 4.220957
#> [14,] 4.337802 4.217920
#> [15,] 4.170241 4.187927
#> [16,] 4.613941 4.521260
#> CCTCAGTCATCATCCC-400.2.2 CCTCAGTGTAGCGATG-400.2.2
#> [1,] 4.404398 4.479152
#> [2,] 4.014661 4.041695
#> [3,] 4.117899 4.270677
#> [4,] 4.070250 4.285714
#> [5,] 4.733659 4.981545
#> [6,] 4.287721 4.430622
#> [7,] 4.445938 4.253589
#> [8,] 4.779475 4.592618
#> [9,] 4.437385 4.316473
#> [10,] 4.058033 4.150376
#> [11,] 4.006109 4.045796
#> [12,] 4.227245 4.170198
#> [13,] 4.313378 4.645249
#> [14,] 4.033598 3.895420
#> [15,] 4.258400 3.867396
#> [16,] 4.417838 4.573479
#> CCTCTGAAGTGGCACA-400.2.2 CCTCTGACATTAGGCT-400.2.2
#> [1,] 4.776596 4.269231
#> [2,] 3.872340 4.383107
#> [3,] 4.370213 4.331071
#> [4,] 4.371631 4.097285
#> [5,] 4.756738 4.745098
#> [6,] 3.921277 4.856712
#> [7,] 4.327660 4.368024
#> [8,] 4.401418 4.975867
#> [9,] 4.358156 4.665913
#> [10,] 3.881560 4.346154
#> [11,] 3.900000 4.483409
#> [12,] 4.014184 4.386124
#> [13,] 4.131206 4.037707
#> [14,] 4.134752 4.383861
#> [15,] 4.131206 4.293363
#> [16,] 4.846099 4.522624
#> CCTCTGACATTATCTC-400.2.2 CCTCTGAGTCATCCCT-400.2.2
#> [1,] 4.287478 4.438727
#> [2,] 3.935332 4.610697
#> [3,] 4.286890 4.307380
#> [4,] 4.152263 4.492891
#> [5,] 5.118754 4.558565
#> [6,] 4.040564 4.513879
#> [7,] 4.899471 4.607312
#> [8,] 4.285714 4.672986
#> [9,] 4.170488 4.792146
#> [10,] 3.881834 4.486798
#> [11,] 4.292769 4.218687
#> [12,] 4.206349 4.328368
#> [13,] 4.043504 4.348003
#> [14,] 4.152263 4.377116
#> [15,] 3.699588 4.215978
#> [16,] 3.884186 4.447529
#> CCTCTGAGTTTAAGCC-400.2.2 CCTTACGCACAGACAG-400.2.2
#> [1,] 4.135930 4.299262
#> [2,] 4.165342 4.150685
#> [3,] 4.220191 4.069547
#> [4,] 4.186804 3.895680
#> [5,] 5.182035 4.308746
#> [6,] 4.059618 4.339305
#> [7,] 4.612083 4.441517
#> [8,] 3.930048 4.972603
#> [9,] 3.826709 4.557429
#> [10,] 4.131955 4.242360
#> [11,] 4.208267 4.351949
#> [12,] 3.983307 4.648051
#> [13,] 4.280604 4.415174
#> [14,] 4.243243 3.889357
#> [15,] 3.797297 3.991570
#> [16,] 4.480127 4.482613
#> CCTTCCCCATACAGCT-400.2.2 CCTTCCCGTAGATTAG-400.2.2
#> [1,] 4.674646 4.003782
#> [2,] 4.451578 3.505295
#> [3,] 4.120783 3.858548
#> [4,] 4.184984 4.680787
#> [5,] 4.659412 3.779879
#> [6,] 4.714908 4.546899
#> [7,] 4.491839 4.114221
#> [8,] 4.874864 4.936460
#> [9,] 4.583243 4.155825
#> [10,] 4.214363 5.798033
#> [11,] 4.139282 5.474281
#> [12,] 4.413493 3.723903
#> [13,] 4.381937 3.490923
#> [14,] 4.242655 4.419818
#> [15,] 4.085963 5.417549
#> [16,] 4.865071 4.956884
#> CCTTCCCTCCTAAGTG-400.2.2 CCTTCGATCGCTAGCG-400.2.2
#> [1,] 4.124236 4.068354
#> [2,] 4.466395 4.374684
#> [3,] 4.441955 3.953165
#> [4,] 4.049898 4.188608
#> [5,] 4.425662 4.460759
#> [6,] 3.835031 4.489873
#> [7,] 4.288187 4.018987
#> [8,] 4.881874 4.786076
#> [9,] 4.662933 4.483544
#> [10,] 4.346232 4.464557
#> [11,] 4.577393 4.198734
#> [12,] 4.377800 4.530380
#> [13,] 4.386965 4.391139
#> [14,] 4.212831 3.755696
#> [15,] 4.204684 4.302532
#> [16,] 4.357434 4.727848
#> CGAACATGTACCATCA-400.2.2 CGACTTCCAGACAAGC-400.2.2
#> [1,] 4.196850 4.370679
#> [2,] 4.458943 3.941741
#> [3,] 4.160855 4.162612
#> [4,] 3.808774 4.153009
#> [5,] 4.624297 5.077465
#> [6,] 4.408324 3.978233
#> [7,] 4.310461 4.666453
#> [8,] 4.650169 4.286812
#> [9,] 4.523060 4.184379
#> [10,] 4.246344 3.795775
#> [11,] 4.483690 4.059539
#> [12,] 4.479190 4.140845
#> [13,] 4.291339 4.269526
#> [14,] 4.073116 4.017926
#> [15,] 4.178853 4.030090
#> [16,] 4.608549 4.301536
#> CGACTTCGTGCACGAA-400.2.2 CGAGAAGAGAATTGTG-400.2.2
#> [1,] 4.215475 4.703833
#> [2,] 4.549461 4.155633
#> [3,] 4.337904 4.245645
#> [4,] 4.123408 4.253775
#> [5,] 5.262488 4.656214
#> [6,] 4.583741 4.214866
#> [7,] 4.403526 4.063298
#> [8,] 4.690500 4.714286
#> [9,] 4.649363 4.070848
#> [10,] 4.218413 3.968060
#> [11,] 4.189030 4.269454
#> [12,] 4.322233 4.221254
#> [13,] 4.614104 3.915796
#> [14,] 4.267385 4.206736
#> [15,] 4.057786 4.070848
#> [16,] 4.539667 4.778165
#> CGAGCACAGGCATTGG-400.2.2 CGAGCACTCTTGCATT-400.2.2
#> [1,] 4.438735 4.331636
#> [2,] 4.426877 4.194909
#> [3,] 4.484848 4.423273
#> [4,] 4.288538 4.217455
#> [5,] 4.416337 4.944000
#> [6,] 4.877470 4.475636
#> [7,] 4.603426 4.453091
#> [8,] 4.537549 4.768000
#> [9,] 4.696970 4.590545
#> [10,] 4.270092 4.304727
#> [11,] 4.283267 4.247273
#> [12,] 4.773386 4.243636
#> [13,] 4.421607 4.570182
#> [14,] 4.183136 4.131636
#> [15,] 4.320158 4.202909
#> [16,] 4.534914 4.458909
#> CGAGCCAAGTACGTTC-400.2.2 CGAGCCAGTTAGGGTG-400.2.2
#> [1,] 4.280385 3.921977
#> [2,] 4.385078 4.317295
#> [3,] 4.269555 4.410923
#> [4,] 3.962696 4.152146
#> [5,] 4.523466 4.525358
#> [6,] 4.610108 4.330299
#> [7,] 4.403129 4.016905
#> [8,] 4.460890 4.634590
#> [9,] 4.596871 4.400520
#> [10,] 4.265945 4.280884
#> [11,] 4.336943 4.410923
#> [12,] 4.534296 4.304291
#> [13,] 4.632972 4.397919
#> [14,] 4.312876 4.362809
#> [15,] 4.375451 4.023407
#> [16,] 4.725632 4.328999
#> CGATCGGAGGTAGCTG-400.2.2 CGATCGGGTCTCGTTC-400.2.2
#> [1,] 4.093057 4.788815
#> [2,] 4.044381 3.737307
#> [3,] 4.123121 4.180280
#> [4,] 3.999284 3.977189
#> [5,] 4.617037 4.707138
#> [6,] 4.164639 4.161148
#> [7,] 4.327130 4.523179
#> [8,] 4.735147 4.157469
#> [9,] 4.630637 4.153054
#> [10,] 4.248389 3.701987
#> [11,] 4.291339 4.541575
#> [12,] 4.413744 4.434143
#> [13,] 4.443808 4.356880
#> [14,] 3.843236 4.261221
#> [15,] 4.076593 4.001472
#> [16,] 4.435934 3.905813
#> CGATTGAAGATCGGGT-400.2.2 CGATTGAGTTGATTGC-400.2.2
#> [1,] 4.310112 4.486364
#> [2,] 4.142697 4.142045
#> [3,] 3.955618 4.140909
#> [4,] 4.161798 4.407955
#> [5,] 4.422472 4.445455
#> [6,] 4.038202 4.501136
#> [7,] 4.516854 4.378409
#> [8,] 4.733146 4.864773
#> [9,] 4.286517 4.542045
#> [10,] 4.338202 4.398864
#> [11,] 4.097753 4.312500
#> [12,] 4.251685 4.723864
#> [13,] 4.391573 4.247727
#> [14,] 4.141573 4.139773
#> [15,] 4.021348 4.052273
#> [16,] 4.223596 4.775000
#> CGCCAAGCAGCTGCTG-400.2.2 CGCGGTATCTACCAGA-400.2.2
#> [1,] 4.344512 4.611765
#> [2,] 4.320122 4.071895
#> [3,] 4.243902 4.546405
#> [4,] 4.621951 3.945098
#> [5,] 4.531504 4.552941
#> [6,] 4.543699 4.865359
#> [7,] 4.385163 4.292810
#> [8,] 5.125000 4.903268
#> [9,] 4.769309 4.850980
#> [10,] 3.975610 4.359477
#> [11,] 4.351626 4.376471
#> [12,] 4.498984 4.270588
#> [13,] 4.533537 4.406536
#> [14,] 4.104675 4.369935
#> [15,] 3.883130 4.430065
#> [16,] 4.527439 4.478431
#> CGCGTTTTCGTGGTCG-400.2.2 CGCTATCAGTCCGGTC-400.2.2
#> [1,] 3.939748 4.578907
#> [2,] 4.761691 3.695920
#> [3,] 3.937950 3.558122
#> [4,] 3.567446 3.989222
#> [5,] 5.142086 5.377983
#> [6,] 3.932554 3.703618
#> [7,] 4.572842 4.605851
#> [8,] 4.976619 4.169361
#> [9,] 3.993705 4.208622
#> [10,] 3.964928 3.498075
#> [11,] 4.866007 4.250962
#> [12,] 3.960432 3.657429
#> [13,] 4.037770 3.970747
#> [14,] 4.899281 4.616628
#> [15,] 3.596223 3.569669
#> [16,] 4.205935 4.207852
#> CGCTATCTCGCCAGCA-400.2.2 CGCTTCAGTACAGTTC-400.2.2
#> [1,] 4.629844 4.063218
#> [2,] 3.603239 4.458621
#> [3,] 3.779641 4.224138
#> [4,] 4.242915 3.982759
#> [5,] 5.390977 4.179310
#> [6,] 3.993638 3.955172
#> [7,] 4.706767 4.457471
#> [8,] 4.289184 4.731034
#> [9,] 4.152689 4.387356
#> [10,] 3.775593 4.321839
#> [11,] 4.082707 4.280460
#> [12,] 3.843262 4.234483
#> [13,] 3.960093 4.226437
#> [14,] 4.244072 4.143678
#> [15,] 3.866975 4.328736
#> [16,] 4.410642 4.733333
#> CGGACACAGCCGGTAA-400.2.2 CGGACACCAGTATAAG-400.2.2
#> [1,] 4.651646 4.482881
#> [2,] 3.632005 4.508855
#> [3,] 3.911034 4.195986
#> [4,] 4.365107 4.085006
#> [5,] 5.206239 4.463991
#> [6,] 4.088966 4.340024
#> [7,] 4.940497 4.451004
#> [8,] 4.039284 4.779221
#> [9,] 4.065280 4.497048
#> [10,] 3.848642 4.726092
#> [11,] 3.956672 4.340024
#> [12,] 4.110341 4.218418
#> [13,] 4.235124 4.527745
#> [14,] 4.145003 4.210153
#> [15,] 3.731947 4.239669
#> [16,] 3.935875 4.853601
#> CGGACACTCACCGTAA-400.2.2 CGGACGTGTGTGAATA-400.2.2
#> [1,] 4.683521 4.474556
#> [2,] 3.996255 4.527811
#> [3,] 3.917603 4.014201
#> [4,] 4.606117 3.902959
#> [5,] 4.800250 4.728994
#> [6,] 4.006866 4.586982
#> [7,] 4.576155 4.172781
#> [8,] 4.591760 4.885207
#> [9,] 4.007491 4.311243
#> [10,] 3.715356 4.497041
#> [11,] 3.622971 4.027219
#> [12,] 3.836454 4.368047
#> [13,] 4.119226 4.262722
#> [14,] 3.989388 4.355030
#> [15,] 4.243446 4.332544
#> [16,] 4.383271 4.200000
#> CGGAGCTAGATATGCA-400.2.2 CGGAGCTCAGGAATCG-400.2.2
#> [1,] 4.312639 4.288256
#> [2,] 4.165188 3.970641
#> [3,] 4.274945 3.669484
#> [4,] 4.181818 3.879893
#> [5,] 5.028825 5.380338
#> [6,] 4.715078 4.071174
#> [7,] 4.508869 5.297153
#> [8,] 4.855876 4.314057
#> [9,] 4.543237 4.069395
#> [10,] 4.442350 3.897242
#> [11,] 4.242794 4.022687
#> [12,] 4.782705 3.918149
#> [13,] 4.802661 4.152135
#> [14,] 4.195122 4.380783
#> [15,] 4.271619 3.697954
#> [16,] 4.334812 3.906584
#> CGGCTAGAGCGCCTCA-400.2.2 CGGCTAGTCCCAACGG-400.2.2
#> [1,] 4.115147 4.541222
#> [2,] 4.166151 4.150339
#> [3,] 4.193199 4.014549
#> [4,] 3.953632 4.181377
#> [5,] 4.687017 4.821532
#> [6,] 4.560278 4.405432
#> [7,] 4.299073 4.112512
#> [8,] 4.289799 4.645975
#> [9,] 4.442813 4.483996
#> [10,] 4.241113 4.193986
#> [11,] 4.444359 4.113482
#> [12,] 4.605873 4.586809
#> [13,] 4.282071 4.636275
#> [14,] 4.088099 4.144520
#> [15,] 3.905719 4.370514
#> [16,] 4.455178 4.574200
#> CGGTTAAGTACGCACC-400.2.2 CGGTTAAGTCCAGTAT-400.2.2
#> [1,] 4.468954 4.372647
#> [2,] 4.114561 3.584065
#> [3,] 4.242316 4.199498
#> [4,] 4.377678 4.103513
#> [5,] 4.779882 4.702008
#> [6,] 4.067370 4.368883
#> [7,] 4.361999 4.658720
#> [8,] 4.536014 4.398369
#> [9,] 4.412605 4.253450
#> [10,] 4.056815 4.111041
#> [11,] 4.242006 4.360100
#> [12,] 4.237038 4.294856
#> [13,] 4.424092 4.388959
#> [14,] 4.056349 4.197616
#> [15,] 4.150264 4.018193
#> [16,] 4.277088 4.217064
#> CGTAGCGCAGATTGCT-400.2.2 CGTCACTAGTCAATAG-400.2.2
#> [1,] 4.523196 4.437359
#> [2,] 3.756873 4.224306
#> [3,] 4.369416 4.574644
#> [4,] 4.363402 4.231058
#> [5,] 5.014605 4.689422
#> [6,] 3.876289 4.729932
#> [7,] 5.409794 4.535634
#> [8,] 4.231959 4.846962
#> [9,] 3.944158 4.735934
#> [10,] 3.926117 4.411103
#> [11,] 4.112543 4.588897
#> [12,] 4.171821 4.344336
#> [13,] 4.167526 4.192048
#> [14,] 4.245704 4.266317
#> [15,] 3.676117 4.171793
#> [16,] 3.904639 4.462866
#> CGTCACTCAAGGCTCC-400.2.2 CGTCACTTCACTCCTG-400.2.2
#> [1,] 4.788316 4.248359
#> [2,] 4.119120 4.248359
#> [3,] 4.354325 4.172867
#> [4,] 4.331942 4.310722
#> [5,] 4.791730 4.719912
#> [6,] 4.128604 4.163020
#> [7,] 4.428680 4.384026
#> [8,] 4.481791 4.451860
#> [9,] 4.511381 4.422319
#> [10,] 3.921093 4.167396
#> [11,] 4.260622 4.504376
#> [12,] 4.422231 4.433260
#> [13,] 4.232170 4.303063
#> [14,] 4.411988 4.170678
#> [15,] 3.877086 4.040481
#> [16,] 4.084977 4.492341
#> CGTCAGGCATTGTGCA-400.2.2 CGTCAGGTCAAGGTAA-400.2.2
#> [1,] 4.535270 4.041878
#> [2,] 4.024896 4.299492
#> [3,] 4.067220 4.416244
#> [4,] 4.248963 4.341371
#> [5,] 4.929461 4.402284
#> [6,] 4.218257 4.192893
#> [7,] 4.447303 4.203046
#> [8,] 4.451452 4.526650
#> [9,] 4.392531 4.571066
#> [10,] 4.107884 4.298223
#> [11,] 4.177593 4.491117
#> [12,] 4.083817 4.681472
#> [13,] 4.373444 3.937817
#> [14,] 4.042324 4.109137
#> [15,] 4.217427 4.350254
#> [16,] 4.400830 4.667513
#> CGTCAGGTCCTAGGGC-400.2.2 CGTCCATCATTCCTCG-400.2.2
#> [1,] 4.331055 4.360478
#> [2,] 4.096967 4.310532
#> [3,] 4.099957 4.427796
#> [4,] 3.973516 4.352877
#> [5,] 4.747971 4.707926
#> [6,] 3.886373 3.994571
#> [7,] 4.470739 4.648208
#> [8,] 4.626655 4.875136
#> [9,] 4.211875 4.671010
#> [10,] 3.771038 4.169381
#> [11,] 4.404528 4.680782
#> [12,] 4.217001 4.168295
#> [13,] 4.233234 4.018458
#> [14,] 4.200769 4.501629
#> [15,] 3.850064 3.939197
#> [16,] 4.298590 4.460369
#> CGTCTACAGTCCCACG-400.2.2 CGTCTACCACAGCCCA-400.2.2
#> [1,] 4.595318 4.246621
#> [2,] 3.796656 4.007209
#> [3,] 4.339799 3.646741
#> [4,] 4.504348 4.007510
#> [5,] 4.648829 5.754881
#> [6,] 5.101003 3.924602
#> [7,] 4.361873 5.415740
#> [8,] 4.803344 4.396515
#> [9,] 4.826756 4.033644
#> [10,] 4.624749 3.914989
#> [11,] 4.457525 4.051968
#> [12,] 4.292977 3.906879
#> [13,] 3.783278 4.175128
#> [14,] 4.562542 4.540102
#> [15,] 4.206689 3.603785
#> [16,] 4.250167 3.979273
#> CGTCTACCATGGTAGG-400.2.2 CGTCTACGTTAAGATG-400.2.2
#> [1,] 4.452395 4.510082
#> [2,] 4.437841 4.125093
#> [3,] 4.375379 4.318148
#> [4,] 4.100667 4.185213
#> [5,] 4.607035 4.538835
#> [6,] 3.916313 4.088125
#> [7,] 4.251061 4.439507
#> [8,] 5.127956 4.498880
#> [9,] 4.246210 4.498506
#> [10,] 4.071559 4.187827
#> [11,] 4.651910 4.542942
#> [12,] 3.986659 4.470500
#> [13,] 4.265009 4.374160
#> [14,] 4.455428 4.225541
#> [15,] 4.038205 4.470500
#> [16,] 4.454821 4.299477
#> CGTGAGCAGAATTCCC-400.2.2 CGTGAGCCATCATCCC-400.2.2
#> [1,] 4.496312 4.536396
#> [2,] 4.338251 3.829682
#> [3,] 4.184405 4.137809
#> [4,] 4.232877 4.290459
#> [5,] 4.126449 4.607067
#> [6,] 4.430980 3.864311
#> [7,] 4.472076 4.522261
#> [8,] 4.709168 4.418375
#> [9,] 4.502634 4.569611
#> [10,] 4.229715 3.809187
#> [11,] 4.241307 3.920848
#> [12,] 4.636459 4.168198
#> [13,] 4.859852 4.185866
#> [14,] 4.021075 3.993640
#> [15,] 4.535300 3.969611
#> [16,] 4.369863 4.212014
#> CGTGAGCGTCTCTTTA-400.2.2 CGTGTAATCTGATACG-400.2.2
#> [1,] 4.218762 4.132684
#> [2,] 4.154245 3.808096
#> [3,] 4.196885 3.883058
#> [4,] 4.039303 4.140930
#> [5,] 4.928810 5.011994
#> [6,] 3.924731 4.197901
#> [7,] 4.827215 5.010495
#> [8,] 4.413793 4.059970
#> [9,] 4.207267 4.100450
#> [10,] 3.852429 3.935532
#> [11,] 4.308862 4.133433
#> [12,] 4.291435 4.089955
#> [13,] 4.219503 4.516492
#> [14,] 4.421209 4.131934
#> [15,] 4.055988 3.673913
#> [16,] 4.259548 4.153673
#> CGTGTCTCACCCAGTG-400.2.2 CGTTAGACATACTCTT-400.2.2
#> [1,] 4.168301 4.262911
#> [2,] 3.859477 4.782864
#> [3,] 4.171024 4.309859
#> [4,] 4.343682 4.299296
#> [5,] 4.872004 4.541080
#> [6,] 3.867647 4.442488
#> [7,] 4.624728 4.169014
#> [8,] 4.311547 4.711268
#> [9,] 4.477124 4.402582
#> [10,] 3.873094 4.312207
#> [11,] 4.142157 4.730047
#> [12,] 4.339869 4.268779
#> [13,] 4.202070 4.383803
#> [14,] 4.382898 4.397887
#> [15,] 3.833333 3.971831
#> [16,] 4.119281 4.482394
#> CGTTCTGGTCCAGTAT-400.2.2 CGTTGGGCATCTGGTA-400.2.2
#> [1,] 4.409176 5.046720
#> [2,] 4.335206 4.127237
#> [3,] 4.305243 4.398608
#> [4,] 4.615169 4.634195
#> [5,] 4.282772 4.364811
#> [6,] 4.481273 4.104374
#> [7,] 4.577715 4.055666
#> [8,] 5.029026 4.536779
#> [9,] 4.759363 4.078529
#> [10,] 4.425094 4.455268
#> [11,] 4.372659 3.999006
#> [12,] 4.503745 4.133201
#> [13,] 4.409176 4.141153
#> [14,] 4.435393 4.274354
#> [15,] 4.278090 4.477137
#> [16,] 4.299625 4.147117
#> CGTTGGGTCAACACGT-400.2.2 CGTTGGGTCACAATGC-400.2.2
#> [1,] 4.298687 4.198520
#> [2,] 4.352298 4.494451
#> [3,] 4.204595 4.302096
#> [4,] 4.187090 4.290999
#> [5,] 4.545952 4.382244
#> [6,] 4.382932 4.415536
#> [7,] 4.273523 4.357583
#> [8,] 4.836980 4.943280
#> [9,] 4.907002 4.307028
#> [10,] 4.452954 4.257707
#> [11,] 4.050328 4.606658
#> [12,] 4.204595 4.239211
#> [13,] 4.386214 4.345253
#> [14,] 4.100656 3.970407
#> [15,] 4.266958 4.113440
#> [16,] 4.728665 4.593095
#> CTAACTTGTGTAACGG-400.2.2 CTAAGACGTCATGCCG-400.2.2
#> [1,] 4.349350 4.533333
#> [2,] 4.449406 4.384314
#> [3,] 4.369135 4.061765
#> [4,] 3.903335 4.145098
#> [5,] 4.509893 4.729412
#> [6,] 3.952516 4.420588
#> [7,] 3.962691 4.093137
#> [8,] 4.631430 4.957843
#> [9,] 4.217072 4.427451
#> [10,] 4.156020 4.474510
#> [11,] 4.281515 4.273529
#> [12,] 4.095534 4.638235
#> [13,] 4.384963 4.296078
#> [14,] 4.711702 4.401961
#> [15,] 4.064443 4.406863
#> [16,] 4.334652 4.707843
#> CTAATGGAGGACACCA-400.2.2 CTAATGGAGGCCCTCA-400.2.2
#> [1,] 4.556317 4.187553
#> [2,] 4.369246 3.757886
#> [3,] 3.900098 4.196078
#> [4,] 4.195886 4.296675
#> [5,] 4.749265 5.078431
#> [6,] 4.299706 3.802217
#> [7,] 4.303624 5.036658
#> [8,] 4.584721 4.396419
#> [9,] 4.564153 4.723785
#> [10,] 4.366308 3.953964
#> [11,] 4.236043 4.254049
#> [12,] 4.523996 4.012788
#> [13,] 4.309500 4.317988
#> [14,] 4.117532 4.609548
#> [15,] 4.197845 3.745098
#> [16,] 4.681685 4.290708
#> CTACACCAGTTCCACA-400.2.2 CTACACCCATCTACGA-400.2.2
#> [1,] 4.419198 4.388430
#> [2,] 4.160996 4.086187
#> [3,] 3.995747 3.992916
#> [4,] 3.953827 4.206612
#> [5,] 4.775820 5.048406
#> [6,] 4.032807 4.664699
#> [7,] 4.478736 4.438017
#> [8,] 4.512758 4.865407
#> [9,] 4.142163 4.907910
#> [10,] 3.986634 4.351830
#> [11,] 4.052248 4.456907
#> [12,] 4.434386 4.515939
#> [13,] 4.288578 4.257379
#> [14,] 3.960510 4.485242
#> [15,] 4.329283 4.356553
#> [16,] 4.425881 4.834711
#> CTACACCCATTGGCGC-400.2.2 CTACATTCAAGTAGTA-400.2.2
#> [1,] 4.260309 4.533100
#> [2,] 4.527491 3.809190
#> [3,] 4.140034 4.004478
#> [4,] 4.008591 4.132788
#> [5,] 4.687285 4.924650
#> [6,] 4.263746 4.192562
#> [7,] 4.254296 4.749026
#> [8,] 4.497423 4.190615
#> [9,] 4.348797 4.184385
#> [10,] 4.341924 4.076713
#> [11,] 4.260309 4.291472
#> [12,] 4.136598 4.169003
#> [13,] 4.409794 4.343069
#> [14,] 4.050687 4.263045
#> [15,] 4.108247 3.911215
#> [16,] 4.520619 4.166083
#> CTACATTGTGCAGACA-400.2.2 CTACATTTCCGCTGTT-400.2.2
#> [1,] 4.812898 4.309343
#> [2,] 4.487261 4.354325
#> [3,] 4.383758 4.112803
#> [4,] 4.207803 4.107958
#> [5,] 4.616242 4.422837
#> [6,] 4.615446 4.286505
#> [7,] 4.048567 4.467128
#> [8,] 4.723726 4.646367
#> [9,] 4.622611 4.429066
#> [10,] 4.209395 4.302422
#> [11,] 4.238057 4.303114
#> [12,] 4.464172 4.386851
#> [13,] 4.277070 4.505190
#> [14,] 4.183121 4.231142
#> [15,] 4.461783 4.231834
#> [16,] 4.769904 4.467820
#> CTACCCACATCAGTAC-400.2.2 CTACGTCCATAAGACA-400.2.2
#> [1,] 4.589041 4.215551
#> [2,] 4.409817 4.279528
#> [3,] 4.126712 4.357283
#> [4,] 4.115297 4.104331
#> [5,] 4.519406 4.373031
#> [6,] 4.723744 4.375984
#> [7,] 4.124429 4.462598
#> [8,] 5.066210 4.513780
#> [9,] 4.955479 4.609252
#> [10,] 4.480594 4.495079
#> [11,] 4.256849 4.105315
#> [12,] 4.413242 4.284449
#> [13,] 4.635845 4.461614
#> [14,] 4.431507 4.024606
#> [15,] 4.009132 4.094488
#> [16,] 4.976027 4.736220
#> CTAGAGTGTGTAATGA-400.2.2 CTAGAGTTCCTCTAGC-400.2.2
#> [1,] 4.648701 4.141907
#> [2,] 4.007792 4.082040
#> [3,] 4.524026 3.853659
#> [4,] 4.455844 4.172949
#> [5,] 4.752597 4.449002
#> [6,] 4.166234 4.523282
#> [7,] 4.372078 4.241685
#> [8,] 4.418831 5.073171
#> [9,] 4.324675 4.370288
#> [10,] 4.205195 4.366962
#> [11,] 4.114286 4.588692
#> [12,] 3.874026 4.436807
#> [13,] 4.029870 4.270510
#> [14,] 4.444156 4.171840
#> [15,] 4.120779 4.315965
#> [16,] 4.211688 4.284922
#> CTAGCCTCAATGGTCT-400.2.2 CTAGTGAGTTAAAGTG-400.2.2
#> [1,] 4.161408 4.728009
#> [2,] 4.169903 4.259259
#> [3,] 4.489078 4.164352
#> [4,] 4.213592 4.508102
#> [5,] 4.586165 4.343750
#> [6,] 4.290049 4.641204
#> [7,] 4.054612 4.285880
#> [8,] 4.759709 4.893519
#> [9,] 4.385922 4.486111
#> [10,] 4.247573 4.452546
#> [11,] 4.320388 4.343750
#> [12,] 4.430825 4.377315
#> [13,] 4.324029 4.400463
#> [14,] 4.347087 4.368056
#> [15,] 4.184466 4.129630
#> [16,] 4.451456 4.399306
#> CTAGTGATCACAACGT-400.2.2 CTCAGAACAGTCAGAG-400.2.2
#> [1,] 4.503673 4.336095
#> [2,] 4.301154 4.181657
#> [3,] 4.036726 4.430769
#> [4,] 4.513641 4.376331
#> [5,] 4.936516 4.659172
#> [6,] 3.939664 4.125444
#> [7,] 4.066107 4.349704
#> [8,] 4.782791 4.705917
#> [9,] 4.594439 4.160355
#> [10,] 3.944386 4.504734
#> [11,] 4.139559 4.324260
#> [12,] 4.241868 4.240828
#> [13,] 4.141133 4.098225
#> [14,] 4.519937 4.247929
#> [15,] 4.081322 4.149112
#> [16,] 4.445435 4.043787
#> CTCAGAAGTAGGAGTC-400.2.2 CTCATTAAGTACGTAA-400.2.2
#> [1,] 4.435109 4.492503
#> [2,] 3.937158 4.160323
#> [3,] 3.984973 4.035755
#> [4,] 4.087432 4.161476
#> [5,] 4.851093 4.817762
#> [6,] 4.066940 4.460208
#> [7,] 4.737022 4.422145
#> [8,] 4.707650 4.986159
#> [9,] 4.275956 4.596309
#> [10,] 3.984290 4.288351
#> [11,] 4.233607 4.656286
#> [12,] 4.259563 4.393310
#> [13,] 4.144126 4.002307
#> [14,] 4.418033 4.404844
#> [15,] 3.967896 4.283737
#> [16,] 4.290984 4.524798
#> CTCATTACAATCAGAA-400.2.2 CTCATTATCCTTTCGG-400.2.2
#> [1,] 4.233065 4.562616
#> [2,] 4.192882 3.311536
#> [3,] 4.384615 3.930290
#> [4,] 4.001148 4.311536
#> [5,] 4.373134 4.475015
#> [6,] 4.346728 3.895126
#> [7,] 4.128588 4.429981
#> [8,] 4.845006 4.368291
#> [9,] 4.918485 4.134485
#> [10,] 4.243398 3.889574
#> [11,] 4.407577 3.793337
#> [12,] 4.653272 4.025910
#> [13,] 4.421355 4.140654
#> [14,] 4.376579 4.404688
#> [15,] 4.290471 4.227020
#> [16,] 4.571757 4.134485
#> CTCGGGAGTGAACCTT-400.2.2 CTCGGGAGTTAGAACA-400.2.2
#> [1,] 4.687673 4.423896
#> [2,] 3.775567 4.198630
#> [3,] 4.009397 4.142314
#> [4,] 4.129906 4.222222
#> [5,] 4.656164 4.729072
#> [6,] 4.185738 4.116438
#> [7,] 4.288004 4.359970
#> [8,] 4.739635 4.617199
#> [9,] 4.546711 4.177321
#> [10,] 3.824765 3.843227
#> [11,] 4.609729 3.919330
#> [12,] 4.212272 4.410198
#> [13,] 4.384190 4.200152
#> [14,] 4.006081 4.146119
#> [15,] 3.902156 4.331811
#> [16,] 4.075732 4.386606
#> CTCGTACAGTGCGTGA-400.2.2 CTCGTACGTACCGTAT-400.2.2
#> [1,] 4.699729 4.346570
#> [2,] 3.683843 4.637786
#> [3,] 4.068578 3.827918
#> [4,] 4.455637 4.267148
#> [5,] 5.103061 4.348977
#> [6,] 3.977141 4.655836
#> [7,] 4.895389 4.209386
#> [8,] 4.255715 4.919374
#> [9,] 4.199148 4.320096
#> [10,] 4.041069 4.977136
#> [11,] 3.972491 4.364621
#> [12,] 3.936071 4.483755
#> [13,] 4.289035 4.238267
#> [14,] 4.442077 4.214200
#> [15,] 3.789616 3.903730
#> [16,] 3.920961 4.362214
#> CTCGTACGTGAGCGAT-400.2.2 CTCGTCAAGTATCTCG-400.2.2
#> [1,] 4.285209 4.619690
#> [2,] 4.236377 3.614295
#> [3,] 4.282378 3.564396
#> [4,] 4.171975 4.335806
#> [5,] 4.510262 5.165206
#> [6,] 4.508139 3.974376
#> [7,] 4.528662 4.915037
#> [8,] 4.811040 4.198247
#> [9,] 4.796886 3.888739
#> [10,] 4.455768 3.720836
#> [11,] 4.548478 3.548213
#> [12,] 4.616419 4.130816
#> [13,] 4.518754 4.431558
#> [14,] 4.128804 4.261632
#> [15,] 4.169851 3.631153
#> [16,] 4.245577 3.979096
#> CTCGTCACATGCGCAC-400.2.2 CTCTAATGTATGAAAC-400.2.2
#> [1,] 4.500478 4.675569
#> [2,] 4.036364 4.083786
#> [3,] 4.084211 4.045194
#> [4,] 4.038278 4.192957
#> [5,] 5.335885 4.796038
#> [6,] 3.702392 4.032575
#> [7,] 4.662201 4.593103
#> [8,] 4.514833 4.466911
#> [9,] 3.810526 4.172120
#> [10,] 3.846890 3.905503
#> [11,] 4.121531 4.287307
#> [12,] 3.844976 4.076596
#> [13,] 4.193301 4.188995
#> [14,] 4.261244 4.319149
#> [15,] 4.117703 3.946588
#> [16,] 4.682297 4.286720
#> CTCTAATGTCAGAATA-400.2.2 CTCTAATGTTTGACAC-400.2.2
#> [1,] 4.402795 4.437965
#> [2,] 4.432020 4.207196
#> [3,] 4.054638 3.933002
#> [4,] 4.108005 4.616625
#> [5,] 4.670902 4.580645
#> [6,] 4.048285 4.468983
#> [7,] 4.236341 4.110422
#> [8,] 4.592122 4.910670
#> [9,] 5.027954 4.425558
#> [10,] 4.325286 4.472705
#> [11,] 4.213469 4.220844
#> [12,] 5.049555 4.131514
#> [13,] 4.607370 4.651365
#> [14,] 4.167726 3.970223
#> [15,] 4.473952 4.029777
#> [16,] 4.750953 4.544665
#> CTCTAATTCATAAAGG-400.2.2 CTCTAATTCTCGTTTA-400.2.2
#> [1,] 4.254545 4.309414
#> [2,] 4.461538 3.889876
#> [3,] 4.212587 3.960213
#> [4,] 3.965035 4.344227
#> [5,] 4.805594 5.215275
#> [6,] 4.574825 3.960924
#> [7,] 4.162238 5.310480
#> [8,] 4.558042 4.347069
#> [9,] 4.758042 4.221314
#> [10,] 4.208392 4.074245
#> [11,] 4.226573 4.372647
#> [12,] 4.478322 4.120782
#> [13,] 4.384615 4.198579
#> [14,] 4.247552 4.404618
#> [15,] 4.288112 3.746359
#> [16,] 4.444755 4.137123
#> CTCTGGTCAGGTCCAC-400.2.2 CTCTGGTTCGTGACAT-400.2.2
#> [1,] 4.003693 4.548256
#> [2,] 4.078287 4.135465
#> [3,] 4.281388 3.998256
#> [4,] 4.039143 3.961628
#> [5,] 4.437962 4.514535
#> [6,] 4.018464 4.229651
#> [7,] 4.949778 4.537209
#> [8,] 4.490399 4.336047
#> [9,] 4.100443 4.242442
#> [10,] 4.016248 4.008140
#> [11,] 4.146972 4.163372
#> [12,] 3.960857 4.402326
#> [13,] 4.405465 4.395930
#> [14,] 4.035451 4.537791
#> [15,] 3.858198 3.972093
#> [16,] 4.542836 4.193605
#> CTGAAACTCTCGCTTG-400.2.2 CTGATCCAGGTGCTTT-400.2.2
#> [1,] 4.163373 4.462250
#> [2,] 4.171278 4.538778
#> [3,] 3.964427 4.198254
#> [4,] 4.085639 4.159219
#> [5,] 4.520422 4.417052
#> [6,] 4.367589 4.589111
#> [7,] 4.259552 4.485876
#> [8,] 4.513834 4.879815
#> [9,] 4.343874 4.621469
#> [10,] 3.981555 4.367232
#> [11,] 4.324111 4.504879
#> [12,] 4.105402 4.586543
#> [13,] 4.525692 4.362096
#> [14,] 4.056653 4.042116
#> [15,] 3.722003 4.092964
#> [16,] 4.864295 4.664612
#> CTGATCCTCTGCTGTC-400.2.2 CTGCCTAGTTGGTAAA-400.2.2
#> [1,] 4.440097 4.535861
#> [2,] 3.811594 4.171107
#> [3,] 3.867633 4.219262
#> [4,] 4.224638 4.324795
#> [5,] 5.059903 4.761270
#> [6,] 4.384541 4.626025
#> [7,] 5.115459 4.111680
#> [8,] 4.308696 5.169057
#> [9,] 4.192271 4.911885
#> [10,] 4.067150 4.189549
#> [11,] 4.158937 4.321721
#> [12,] 4.071014 4.599385
#> [13,] 4.207729 4.515369
#> [14,] 4.474396 4.328893
#> [15,] 3.800966 4.060451
#> [16,] 4.389372 4.293033
#> CTGCCTATCGTTACAG-400.2.2 CTGGTCTCACGACGAA-400.2.2
#> [1,] 4.303536 4.157343
#> [2,] 4.322882 4.334499
#> [3,] 4.571047 4.099068
#> [4,] 4.064710 4.090909
#> [5,] 4.590394 4.374126
#> [6,] 4.268846 4.144522
#> [7,] 4.055370 4.257576
#> [8,] 4.829219 4.674825
#> [9,] 4.392262 4.423077
#> [10,] 3.888592 4.516317
#> [11,] 4.324883 4.259907
#> [12,] 4.286858 4.244755
#> [13,] 4.258839 4.813520
#> [14,] 4.036691 4.320513
#> [15,] 4.029353 4.201632
#> [16,] 4.605737 4.653846
#> CTGGTCTCAGACGTAG-400.2.2 CTGGTCTCATAGGATA-400.2.2
#> [1,] 4.450194 4.231867
#> [2,] 4.324709 4.200951
#> [3,] 4.346701 4.605232
#> [4,] 4.076326 4.046373
#> [5,] 4.278137 4.618312
#> [6,] 4.311772 4.278240
#> [7,] 4.131953 4.202140
#> [8,] 4.776197 4.681332
#> [9,] 4.593790 4.395957
#> [10,] 3.877102 4.198573
#> [11,] 4.194049 4.518430
#> [12,] 4.388098 4.639715
#> [13,] 4.366106 4.274673
#> [14,] 4.289780 3.900119
#> [15,] 3.780078 3.989298
#> [16,] 4.873221 4.689655
#> CTGGTCTGTTGCGTTA-400.2.2 CTTAACTGTTGCCTCT-400.2.2
#> [1,] 4.462154 4.405669
#> [2,] 4.012373 4.087245
#> [3,] 4.085153 4.258193
#> [4,] 4.490539 4.326395
#> [5,] 4.501456 4.503100
#> [6,] 4.314410 4.088131
#> [7,] 4.200873 4.462356
#> [8,] 4.882824 4.804694
#> [9,] 4.503639 4.281222
#> [10,] 4.167394 4.142604
#> [11,] 4.026201 4.543844
#> [12,] 4.162300 4.268822
#> [13,] 4.402475 4.271036
#> [14,] 4.201601 4.264393
#> [15,] 4.005095 4.066873
#> [16,] 4.499272 4.379097
#> CTTAGGAAGCAGATCG-400.2.2 CTTCTCTGTTTCCACC-400.2.2
#> [1,] 4.312977 4.283544
#> [2,] 4.284351 3.925316
#> [3,] 4.609733 4.112658
#> [4,] 4.316794 4.275949
#> [5,] 4.333969 4.855696
#> [6,] 4.553435 4.143038
#> [7,] 3.967557 4.364557
#> [8,] 4.989504 4.377215
#> [9,] 4.672710 4.346835
#> [10,] 4.524809 4.303797
#> [11,] 4.443702 4.130380
#> [12,] 4.424618 4.139241
#> [13,] 4.323473 4.398734
#> [14,] 4.276718 4.146835
#> [15,] 4.072519 3.859494
#> [16,] 4.449427 4.226582
#> CTTTGCGAGCCAGTAG-400.2.2 GAAATGAAGGGCTCTC-400.2.2
#> [1,] 4.625101 4.455670
#> [2,] 3.534413 4.201031
#> [3,] 3.842105 4.187629
#> [4,] 4.363563 4.137113
#> [5,] 5.388664 4.548454
#> [6,] 3.820243 4.360825
#> [7,] 4.847773 4.429897
#> [8,] 4.222672 5.048454
#> [9,] 4.076113 4.586598
#> [10,] 3.543320 4.672165
#> [11,] 3.808907 4.382474
#> [12,] 3.745749 4.815464
#> [13,] 4.140891 4.422680
#> [14,] 4.254251 4.181443
#> [15,] 3.752227 4.262887
#> [16,] 3.799190 4.745361
#> GAACCTAAGGTGACCA-400.2.2 GAACGGACAAGGACTG-400.2.2
#> [1,] 4.557561 4.432648
#> [2,] 3.557561 4.085616
#> [3,] 3.766829 3.713470
#> [4,] 4.054146 4.026256
#> [5,] 5.460488 4.920091
#> [6,] 3.798049 3.803653
#> [7,] 4.601463 4.507991
#> [8,] 4.052683 4.578767
#> [9,] 3.822927 4.159817
#> [10,] 3.826829 3.880137
#> [11,] 4.233171 3.883562
#> [12,] 3.843902 4.500000
#> [13,] 4.033171 4.167808
#> [14,] 4.210732 4.226027
#> [15,] 3.989268 4.324201
#> [16,] 4.600000 4.327626
#> GAACGGATCTTTACGT-400.2.2 GAATAAGAGATGCCTT-400.2.2
#> [1,] 4.541802 4.341725
#> [2,] 4.312704 4.283916
#> [3,] 4.150923 3.997669
#> [4,] 4.155266 4.209324
#> [5,] 4.650380 4.807925
#> [6,] 4.217155 4.193473
#> [7,] 3.958740 4.235431
#> [8,] 4.799131 4.860140
#> [9,] 4.634093 4.479720
#> [10,] 4.462541 4.022378
#> [11,] 4.244300 4.131002
#> [12,] 4.615635 4.253147
#> [13,] 4.608035 4.497436
#> [14,] 4.092291 4.082517
#> [15,] 4.141151 3.963170
#> [16,] 4.485342 4.254545
#> GAATGAATCATGCTCC-400.2.2 GACACGCCAGTCAGAG-400.2.2
#> [1,] 4.341368 4.333967
#> [2,] 4.710762 3.854246
#> [3,] 4.313341 4.084284
#> [4,] 4.563901 4.371990
#> [5,] 4.655269 4.624842
#> [6,] 4.409753 4.092522
#> [7,] 4.580717 4.948669
#> [8,] 4.953475 4.634347
#> [9,] 4.636771 4.457541
#> [10,] 4.323430 4.097592
#> [11,] 4.365471 4.444867
#> [12,] 4.451794 4.145754
#> [13,] 4.151906 4.000634
#> [14,] 4.359305 4.264259
#> [15,] 4.146861 3.964512
#> [16,] 4.289238 4.234474
#> GACACGCGTCCGTGAC-400.2.2 GACAGAGCAAGTCTAC-400.2.2
#> [1,] 4.282417 4.159907
#> [2,] 4.591989 4.125145
#> [3,] 4.113374 4.184241
#> [4,] 4.008826 3.789108
#> [5,] 4.676171 4.904983
#> [6,] 4.419552 4.050985
#> [7,] 4.575017 4.604867
#> [8,] 4.612356 4.889919
#> [9,] 4.590631 4.516802
#> [10,] 4.334012 4.465817
#> [11,] 4.429056 4.049826
#> [12,] 4.648337 4.608343
#> [13,] 4.362525 4.491309
#> [14,] 4.404616 4.241020
#> [15,] 4.513238 4.174971
#> [16,] 4.604209 4.771727
#> GACAGAGCATCACGAT-400.2.2 GACAGAGTCGGAGGTA-400.2.2
#> [1,] 4.197740 4.412245
#> [2,] 4.311864 3.495238
#> [3,] 4.203390 3.651701
#> [4,] 3.707345 4.257143
#> [5,] 4.778531 5.121769
#> [6,] 3.992090 3.953061
#> [7,] 3.990960 5.303401
#> [8,] 4.853107 4.000000
#> [9,] 4.533333 4.073469
#> [10,] 4.540113 3.765986
#> [11,] 4.105085 3.910204
#> [12,] 4.282486 3.870068
#> [13,] 4.636158 4.365306
#> [14,] 4.023729 4.542177
#> [15,] 4.344633 3.553741
#> [16,] 4.590960 4.115646
#> GACGCGTAGGATCGCA-400.2.2 GACGGCTTCCCATTTA-400.2.2
#> [1,] 4.263603 4.534942
#> [2,] 3.969367 3.569101
#> [3,] 4.060459 4.144469
#> [4,] 4.248287 4.420558
#> [5,] 5.078597 5.247885
#> [6,] 3.806530 3.827640
#> [7,] 5.147924 4.961454
#> [8,] 4.592906 4.194296
#> [9,] 4.022168 3.935443
#> [10,] 3.838775 3.761830
#> [11,] 4.219669 4.231902
#> [12,] 3.831116 4.109683
#> [13,] 4.270859 4.055782
#> [14,] 4.440145 4.328110
#> [15,] 3.600967 4.094641
#> [16,] 3.960097 4.176120
#> GACTACACAGCGTTCG-400.2.2 GACTACACAGTATAAG-400.2.2
#> [1,] 4.406040 4.227799
#> [2,] 4.217002 4.315315
#> [3,] 4.276286 4.379665
#> [4,] 4.419463 4.339768
#> [5,] 5.134228 4.688546
#> [6,] 4.633110 4.048906
#> [7,] 4.229306 4.036036
#> [8,] 4.721477 4.673102
#> [9,] 4.966443 4.405405
#> [10,] 4.350112 4.144144
#> [11,] 4.416107 4.087516
#> [12,] 4.352349 4.540541
#> [13,] 4.715884 4.540541
#> [14,] 4.091723 3.879022
#> [15,] 4.116331 4.133848
#> [16,] 4.384787 4.342342
#> GAGCAGATCAGAGGTG-400.2.2 GAGCAGATCTTCATGT-400.2.2
#> [1,] 4.149837 4.303468
#> [2,] 4.440825 4.114644
#> [3,] 4.156352 4.352601
#> [4,] 4.323561 3.931599
#> [5,] 4.631922 4.569364
#> [6,] 4.249729 4.541426
#> [7,] 4.038002 4.621387
#> [8,] 4.906623 4.689788
#> [9,] 4.656895 4.493256
#> [10,] 4.424539 4.438343
#> [11,] 4.115092 4.660886
#> [12,] 4.259501 4.637765
#> [13,] 4.311618 3.833333
#> [14,] 4.138979 4.259152
#> [15,] 4.292074 4.561657
#> [16,] 4.560261 4.424855
#> GAGGTGAAGGATGGAA-400.2.2 GAGGTGACATTCTCAT-400.2.2
#> [1,] 4.255046 4.267221
#> [2,] 3.828440 4.420428
#> [3,] 4.209480 4.437055
#> [4,] 4.114067 4.557007
#> [5,] 5.112844 4.510689
#> [6,] 3.761162 4.441805
#> [7,] 4.720489 4.288599
#> [8,] 4.455963 4.680523
#> [9,] 4.118654 4.735154
#> [10,] 3.968807 4.332542
#> [11,] 4.041896 4.625891
#> [12,] 4.367890 4.385986
#> [13,] 4.285933 4.445368
#> [14,] 3.989602 3.915677
#> [15,] 4.369113 4.083135
#> [16,] 4.414067 4.833729
#> GAGGTGAGTCTAGCCG-400.2.2 GAGGTGATCCCTAATT-400.2.2
#> [1,] 4.059165 4.217129
#> [2,] 3.953596 4.554885
#> [3,] 3.997680 4.284680
#> [4,] 4.030162 3.913148
#> [5,] 4.580046 4.287093
#> [6,] 3.863109 4.665862
#> [7,] 4.676334 4.347407
#> [8,] 4.561485 4.788902
#> [9,] 4.428074 4.722557
#> [10,] 4.013921 4.609168
#> [11,] 3.973318 4.455971
#> [12,] 4.337587 4.564536
#> [13,] 4.568445 4.503016
#> [14,] 4.004640 4.372738
#> [15,] 4.323666 4.340169
#> [16,] 4.444316 4.639324
#> GATCAGTAGGATTCGG-400.2.2 GATCAGTAGTGCAAGC-400.2.2
#> [1,] 4.232737 4.857341
#> [2,] 4.456522 3.765928
#> [3,] 4.301790 4.022853
#> [4,] 4.282609 4.466759
#> [5,] 4.281330 5.009695
#> [6,] 4.327366 4.077562
#> [7,] 4.258312 4.283241
#> [8,] 4.915601 4.398199
#> [9,] 4.723785 4.087950
#> [10,] 4.450128 3.756233
#> [11,] 4.406650 4.267313
#> [12,] 4.383632 3.780471
#> [13,] 4.450128 4.155817
#> [14,] 4.246803 4.184211
#> [15,] 4.244246 4.403740
#> [16,] 4.864450 4.323407
#> GATCAGTTCCAACCAA-400.2.2 GATCGATGTGTAATGA-400.2.2
#> [1,] 4.442777 4.633188
#> [2,] 4.294559 3.733624
#> [3,] 4.337711 3.951341
#> [4,] 4.175422 4.489083
#> [5,] 4.651032 4.898316
#> [6,] 4.244841 3.784779
#> [7,] 4.133208 4.661884
#> [8,] 4.942777 4.345602
#> [9,] 4.856473 4.429819
#> [10,] 4.114447 3.626949
#> [11,] 4.276735 3.935745
#> [12,] 4.426829 4.068621
#> [13,] 4.255159 4.321273
#> [14,] 4.184803 4.135371
#> [15,] 4.192308 3.900811
#> [16,] 4.688555 4.183406
#> GATCGCGAGCTGAAAT-400.2.2 GATCGCGAGTGTACCT-400.2.2
#> [1,] 4.719788 4.230406
#> [2,] 3.901726 3.906043
#> [3,] 3.941567 4.128895
#> [4,] 4.737716 4.432483
#> [5,] 5.094954 4.882436
#> [6,] 4.002656 3.964117
#> [7,] 4.907703 4.615203
#> [8,] 4.318725 4.389518
#> [9,] 4.457503 4.014164
#> [10,] 3.945551 4.107177
#> [11,] 4.142098 4.156752
#> [12,] 3.996680 4.170916
#> [13,] 4.158035 4.108593
#> [14,] 4.278884 4.231822
#> [15,] 3.887782 3.950897
#> [16,] 3.865206 4.107649
#> GATCGCGGTTTGACTG-400.2.2 GATCGTACACCAGCAC-400.2.2
#> [1,] 4.236047 4.215259
#> [2,] 4.655814 4.112398
#> [3,] 4.460465 4.094687
#> [4,] 4.218605 4.176431
#> [5,] 4.466279 4.568801
#> [6,] 4.048837 4.157357
#> [7,] 4.279070 4.321526
#> [8,] 4.741860 4.648501
#> [9,] 4.683721 4.315395
#> [10,] 4.536047 4.136921
#> [11,] 4.237209 4.160763
#> [12,] 4.494186 4.282698
#> [13,] 4.388372 4.519074
#> [14,] 4.386047 3.980245
#> [15,] 4.074419 3.868529
#> [16,] 4.430233 4.215940
#> GATCTAGTCTGTCTCG-400.2.2 GATGCTACAGGGAGAG-400.2.2
#> [1,] 4.311230 4.254054
#> [2,] 4.218182 4.416216
#> [3,] 4.232086 4.372973
#> [4,] 4.060963 4.185946
#> [5,] 4.785027 4.449730
#> [6,] 4.310160 4.419459
#> [7,] 4.340107 4.314595
#> [8,] 4.718717 4.931892
#> [9,] 4.751872 4.860541
#> [10,] 4.279144 4.229189
#> [11,] 4.332620 4.452973
#> [12,] 4.406417 4.604324
#> [13,] 4.398930 4.384865
#> [14,] 4.000000 4.196757
#> [15,] 4.190374 3.794595
#> [16,] 4.426738 4.770811
#> GATTCAGGTTGAACTC-400.2.2 GCAAACTAGTGGGCTA-400.2.2
#> [1,] 4.570342 4.577175
#> [2,] 3.508238 3.736202
#> [3,] 3.913815 3.855005
#> [4,] 4.001901 4.104771
#> [5,] 5.454373 4.797942
#> [6,] 3.965779 3.826006
#> [7,] 5.326362 4.663237
#> [8,] 4.126743 4.311506
#> [9,] 3.956274 4.241347
#> [10,] 3.705323 3.920486
#> [11,] 3.899873 3.816651
#> [12,] 3.828897 4.060804
#> [13,] 4.439163 4.868101
#> [14,] 4.507605 3.985033
#> [15,] 3.916984 3.700655
#> [16,] 4.309252 4.246024
#> GCAAACTTCCGATATG-400.2.2 GCACTCTAGATTACCC-400.2.2
#> [1,] 4.268446 4.571588
#> [2,] 3.717425 3.998881
#> [3,] 3.863422 3.963087
#> [4,] 4.184197 4.294183
#> [5,] 5.606489 4.715324
#> [6,] 4.028781 4.024049
#> [7,] 5.211931 4.475391
#> [8,] 3.935636 4.375839
#> [9,] 3.911565 4.373043
#> [10,] 4.067504 4.075503
#> [11,] 4.174778 3.967002
#> [12,] 4.226583 4.110179
#> [13,] 4.492412 4.252237
#> [14,] 4.240712 4.240492
#> [15,] 3.579801 4.002237
#> [16,] 4.074307 4.349553
#> GCACTCTCAGGGTACA-400.2.2 GCACTCTTCACCCTCA-400.2.2
#> [1,] 4.647296 4.479054
#> [2,] 3.468303 4.070270
#> [3,] 3.562150 4.240541
#> [4,] 4.029832 4.377027
#> [5,] 5.484773 4.861486
#> [6,] 4.087011 4.116216
#> [7,] 5.177129 4.631757
#> [8,] 3.897763 4.394595
#> [9,] 3.750777 4.087162
#> [10,] 3.542884 3.887162
#> [11,] 4.143257 4.089865
#> [12,] 3.967060 4.027703
#> [13,] 4.446861 4.083108
#> [14,] 3.958048 3.945270
#> [15,] 3.590118 4.231757
#> [16,] 3.855500 4.304054
#> GCAGCCAAGTGCGTGA-400.2.2 GCAGTTAAGCGTAGTG-400.2.2
#> [1,] 4.621908 4.434489
#> [2,] 4.317206 3.944210
#> [3,] 4.273987 3.831784
#> [4,] 4.270182 3.894336
#> [5,] 4.513998 5.245139
#> [6,] 4.471596 4.085376
#> [7,] 4.245991 4.398986
#> [8,] 5.059799 4.528318
#> [9,] 4.709160 3.823331
#> [10,] 4.330253 3.947591
#> [11,] 4.335961 3.718512
#> [12,] 4.360968 4.482671
#> [13,] 4.437891 4.299239
#> [14,] 4.406632 4.047337
#> [15,] 4.075020 4.262046
#> [16,] 4.413428 4.123415
#> GCAGTTATCGGAAATA-400.2.2 GCATACACATCTATGG-400.2.2
#> [1,] 4.086672 4.467807
#> [2,] 4.160059 3.757042
#> [3,] 4.152678 4.250503
#> [4,] 4.096584 3.946177
#> [5,] 4.836356 4.588531
#> [6,] 4.085407 4.295775
#> [7,] 4.827921 4.543763
#> [8,] 4.382539 4.433602
#> [9,] 4.383172 4.343561
#> [10,] 4.100169 4.122736
#> [11,] 4.250527 4.404930
#> [12,] 4.169338 4.296781
#> [13,] 4.272248 4.160966
#> [14,] 4.324125 4.155936
#> [15,] 3.920287 3.889336
#> [16,] 4.259595 4.206740
#> GCATGATAGCGACGTA-400.2.2 GCATGATAGTACTTGC-400.2.2
#> [1,] 4.428571 4.287458
#> [2,] 4.488550 4.289678
#> [3,] 4.067612 4.163152
#> [4,] 4.467830 4.392897
#> [5,] 4.472192 4.311876
#> [6,] 4.284624 4.157603
#> [7,] 4.165758 4.201998
#> [8,] 4.990185 4.708102
#> [9,] 4.447110 4.703663
#> [10,] 4.308615 4.506104
#> [11,] 4.398037 4.211987
#> [12,] 4.329335 4.503885
#> [13,] 4.279171 4.685905
#> [14,] 4.151581 4.140954
#> [15,] 3.896401 4.144284
#> [16,] 4.194111 4.302997
#> GCATGATCAATTGCTG-400.2.2 GCATGATGTGTGGTTT-400.2.2
#> [1,] 4.620799 4.384362
#> [2,] 3.356373 4.012080
#> [3,] 3.498415 4.033165
#> [4,] 4.247939 4.278717
#> [5,] 5.308814 4.660883
#> [6,] 3.965124 4.303756
#> [7,] 4.828789 4.440369
#> [8,] 4.149651 4.501208
#> [9,] 3.894737 4.301559
#> [10,] 3.826252 3.955634
#> [11,] 3.658212 4.171975
#> [12,] 3.978440 4.086317
#> [13,] 4.355105 4.285965
#> [14,] 4.348129 4.284867
#> [15,] 3.868738 3.846694
#> [16,] 3.821179 4.182297
#> GCATGCGCAACACGCC-400.2.2 GCATGTAAGTAGTGCG-400.2.2
#> [1,] 4.141499 4.081379
#> [2,] 4.343189 4.184828
#> [3,] 4.213305 4.397241
#> [4,] 4.194298 3.960000
#> [5,] 4.557550 4.548966
#> [6,] 4.401267 4.568276
#> [7,] 4.117212 4.307586
#> [8,] 4.934530 4.602759
#> [9,] 4.817318 4.411034
#> [10,] 4.405491 4.380690
#> [11,] 4.486800 4.423448
#> [12,] 4.500528 4.866207
#> [13,] 4.467793 4.398621
#> [14,] 4.093981 4.121379
#> [15,] 4.015839 4.282759
#> [16,] 4.515312 4.211034
#> GCATGTATCCGCAGTG-400.2.2 GCCAAATGTCACCCAG-400.2.2
#> [1,] 4.311385 4.983178
#> [2,] 4.434842 3.664798
#> [3,] 4.065844 3.841121
#> [4,] 4.170096 4.499688
#> [5,] 4.581619 4.670405
#> [6,] 4.414266 3.930218
#> [7,] 4.224966 4.350779
#> [8,] 4.641975 4.507788
#> [9,] 4.659808 4.204984
#> [10,] 4.459534 3.826791
#> [11,] 4.098765 3.796262
#> [12,] 4.296296 4.078505
#> [13,] 5.021948 4.204984
#> [14,] 4.392318 4.223676
#> [15,] 4.189300 3.958255
#> [16,] 5.026063 3.963240
#> GCGAGAACACCAGGCT-400.2.2 GCGAGAAGTTACAGAA-400.2.2
#> [1,] 4.206177 4.789983
#> [2,] 4.195326 3.788845
#> [3,] 4.219533 3.987479
#> [4,] 4.462437 4.209448
#> [5,] 4.469950 5.012521
#> [6,] 4.269616 3.838930
#> [7,] 4.191152 4.661924
#> [8,] 4.761269 4.718270
#> [9,] 4.737896 3.861127
#> [10,] 4.384808 3.754696
#> [11,] 4.201169 4.151964
#> [12,] 4.633556 4.107570
#> [13,] 4.645242 4.332954
#> [14,] 4.091820 4.228230
#> [15,] 4.174457 4.232783
#> [16,] 4.436561 4.353443
#> GCGCAACAGGATCGCA-400.2.2 GCGCAACGTCCTCTTG-400.2.2
#> [1,] 4.295570 4.421387
#> [2,] 3.926582 3.983237
#> [3,] 4.271519 4.434104
#> [4,] 4.070253 4.240462
#> [5,] 5.110127 4.537572
#> [6,] 4.003165 4.854335
#> [7,] 5.020886 4.354913
#> [8,] 4.429114 4.889595
#> [9,] 4.225949 4.828324
#> [10,] 4.027215 4.406358
#> [11,] 4.502532 4.767630
#> [12,] 4.109494 4.464740
#> [13,] 4.196203 3.902312
#> [14,] 4.324684 4.531214
#> [15,] 3.712658 4.138728
#> [16,] 4.185443 4.305202
#> GCGCAGTTCAACGGCC-400.2.2 GCGCCAATCTCATTCA-400.2.2
#> [1,] 4.210121 4.572322
#> [2,] 4.249725 4.118881
#> [3,] 4.336634 4.254325
#> [4,] 4.099010 4.238866
#> [5,] 4.298130 4.871550
#> [6,] 4.489549 4.155686
#> [7,] 4.308031 4.419212
#> [8,] 4.837184 4.584100
#> [9,] 4.511551 4.358484
#> [10,] 4.073707 4.216415
#> [11,] 4.272827 4.510858
#> [12,] 4.599560 4.315789
#> [13,] 4.828383 4.165256
#> [14,] 3.862486 4.169672
#> [15,] 4.070407 4.068090
#> [16,] 4.453245 4.461170
#> GCGCGATCAAGTTAAG-400.2.2 GCTCCTAAGTGTCCCG-400.2.2
#> [1,] 4.548344 4.633174
#> [2,] 4.517881 3.969697
#> [3,] 4.388079 4.055024
#> [4,] 4.307285 3.959330
#> [5,] 4.380132 4.988038
#> [6,] 4.589404 3.932217
#> [7,] 4.165563 4.525518
#> [8,] 4.535099 4.241627
#> [9,] 4.699338 4.134769
#> [10,] 4.242384 3.838915
#> [11,] 4.588079 4.261563
#> [12,] 4.299338 3.997608
#> [13,] 4.780132 4.222488
#> [14,] 4.321854 4.195375
#> [15,] 3.994702 4.022329
#> [16,] 4.521854 4.772727
#> GCTCCTATCAGGTAAA-400.2.2 GCTGCGATCCTCAACC-400.2.2
#> [1,] 4.682734 4.371837
#> [2,] 4.346188 4.512651
#> [3,] 4.262927 3.754675
#> [4,] 4.075372 4.161716
#> [5,] 4.476775 4.431243
#> [6,] 4.269939 4.682068
#> [7,] 4.545136 4.611661
#> [8,] 4.638913 5.015402
#> [9,] 4.286591 4.035204
#> [10,] 3.826468 4.814081
#> [11,] 4.184049 4.658966
#> [12,] 4.065732 4.161716
#> [13,] 4.264680 4.213421
#> [14,] 3.972831 4.276128
#> [15,] 4.218230 3.881188
#> [16,] 4.693252 4.625963
#> GCTGCTTTCAGTACGT-400.2.2 GCTTCCATCAGGCCCA-400.2.2
#> [1,] 4.374696 4.443939
#> [2,] 4.097324 3.818182
#> [3,] 4.163828 3.908333
#> [4,] 4.250608 4.357576
#> [5,] 4.790754 4.937879
#> [6,] 3.851582 4.062121
#> [7,] 4.617194 4.401515
#> [8,] 4.330900 4.356061
#> [9,] 4.103001 4.124242
#> [10,] 4.497161 4.157576
#> [11,] 4.083536 3.828030
#> [12,] 4.326845 3.957576
#> [13,] 4.288727 4.375000
#> [14,] 4.019465 4.288636
#> [15,] 4.154096 3.800000
#> [16,] 4.238443 4.278030
#> GCTTGAACATGTAGTC-400.2.2 GCTTGAATCCGAAGAG-400.2.2
#> [1,] 4.401679 4.433218
#> [2,] 4.022782 4.023529
#> [3,] 4.178657 4.453287
#> [4,] 4.162670 4.325952
#> [5,] 4.590727 4.751557
#> [6,] 4.284572 4.077509
#> [7,] 4.664668 4.521107
#> [8,] 4.592326 4.206920
#> [9,] 4.212630 4.424913
#> [10,] 4.063549 3.910727
#> [11,] 4.176259 4.382007
#> [12,] 4.116307 4.597924
#> [13,] 4.535572 4.269204
#> [14,] 4.167066 4.298270
#> [15,] 4.135492 4.391003
#> [16,] 4.286571 4.559170
#> GGAAAGCTCGCTGATA-400.2.2 GGAATAAAGATGCCTT-400.2.2
#> [1,] 4.939003 4.580890
#> [2,] 3.756012 4.284473
#> [3,] 4.007038 4.330076
#> [4,] 4.192962 4.223670
#> [5,] 5.063930 4.440825
#> [6,] 3.941935 4.598263
#> [7,] 4.150147 4.413681
#> [8,] 4.596481 4.923996
#> [9,] 3.963636 4.601520
#> [10,] 3.882698 4.142237
#> [11,] 4.040469 3.985885
#> [12,] 3.941935 4.679696
#> [13,] 4.097361 4.519001
#> [14,] 3.975953 3.731813
#> [15,] 4.371848 4.322476
#> [16,] 4.323167 4.838219
#> GGAATAAGTGCGAAAC-400.2.2 GGAATAATCAAACGGG-400.2.2
#> [1,] 4.266667 4.372171
#> [2,] 3.770370 3.529338
#> [3,] 4.148822 3.899832
#> [4,] 4.377104 4.226739
#> [5,] 5.061953 5.576278
#> [6,] 3.870707 3.966890
#> [7,] 4.801347 5.444258
#> [8,] 4.675421 3.969405
#> [9,] 4.107071 4.037720
#> [10,] 3.774411 3.800922
#> [11,] 4.144781 3.936714
#> [12,] 4.125253 3.945516
#> [13,] 4.098990 4.142917
#> [14,] 4.234343 4.308885
#> [15,] 3.806734 3.610645
#> [16,] 4.063300 3.844510
#> GGAATAATCTCTTATG-400.2.2 GGACAAGAGAGAACAG-400.2.2
#> [1,] 4.305750 4.531375
#> [2,] 3.549088 4.337784
#> [3,] 3.997195 4.036048
#> [4,] 3.892707 3.822430
#> [5,] 5.514727 4.600801
#> [6,] 3.629032 4.221629
#> [7,] 5.392006 4.013351
#> [8,] 4.079944 4.552737
#> [9,] 3.995792 4.437917
#> [10,] 3.729313 4.197597
#> [11,] 4.144460 3.931909
#> [12,] 4.086957 4.591455
#> [13,] 3.995792 4.475300
#> [14,] 4.508415 4.156208
#> [15,] 3.674614 4.130841
#> [16,] 4.124123 4.452603
#> GGACAAGAGCCACTAT-400.2.2 GGACAAGTCGAGAGCA-400.2.2
#> [1,] 4.215980 4.532211
#> [2,] 4.157303 3.782577
#> [3,] 4.405743 3.950952
#> [4,] 4.151061 3.913616
#> [5,] 4.664170 5.166179
#> [6,] 4.357054 3.929722
#> [7,] 4.440699 4.846999
#> [8,] 4.459426 4.172767
#> [9,] 4.478152 4.106881
#> [10,] 4.549313 3.857980
#> [11,] 4.528090 3.977306
#> [12,] 4.465668 3.785505
#> [13,] 4.228464 4.173499
#> [14,] 4.021223 4.336750
#> [15,] 4.420724 4.231332
#> [16,] 4.795256 4.489751
#> GGACAGAAGGTAGCCA-400.2.2 GGACAGATCACCCGAG-400.2.2
#> [1,] 4.372093 4.768577
#> [2,] 4.194614 4.443737
#> [3,] 4.166463 4.312102
#> [4,] 4.421053 4.227176
#> [5,] 4.323133 4.301486
#> [6,] 4.341493 4.648620
#> [7,] 4.299878 4.218684
#> [8,] 4.805386 4.884289
#> [9,] 4.340269 4.432059
#> [10,] 4.193390 4.118896
#> [11,] 4.315789 4.277070
#> [12,] 4.561812 4.237792
#> [13,] 4.668299 4.283439
#> [14,] 4.004896 4.106157
#> [15,] 4.111383 3.975584
#> [16,] 4.638923 4.453291
#> GGACATTAGAGCCTAG-400.2.2 GGACATTGTATCAGTC-400.2.2
#> [1,] 4.616337 3.951282
#> [2,] 4.620050 4.651282
#> [3,] 4.319307 4.441026
#> [4,] 3.981436 4.158974
#> [5,] 4.815594 4.567949
#> [6,] 4.518564 4.167949
#> [7,] 4.316832 4.185897
#> [8,] 4.714109 4.457692
#> [9,] 4.860149 4.278205
#> [10,] 4.238861 4.146154
#> [11,] 4.519802 4.178205
#> [12,] 4.580446 4.388462
#> [13,] 4.814356 4.230769
#> [14,] 4.397277 4.376923
#> [15,] 4.237624 4.046154
#> [16,] 4.595297 4.532051
#> GGACATTGTGGTCTCG-400.2.2 GGATGTTTCCGCGTTT-400.2.2
#> [1,] 4.481259 4.365591
#> [2,] 4.136432 4.678091
#> [3,] 4.033733 4.329301
#> [4,] 4.200900 4.115591
#> [5,] 4.883808 4.689516
#> [6,] 4.096702 4.540995
#> [7,] 4.619940 4.799059
#> [8,] 4.596702 4.725806
#> [9,] 4.287106 4.267473
#> [10,] 4.198651 4.501344
#> [11,] 4.137931 4.303763
#> [12,] 4.283358 4.698253
#> [13,] 4.359820 4.069220
#> [14,] 3.994003 4.065188
#> [15,] 3.939280 4.594086
#> [16,] 4.427286 4.520833
#> GGATTACAGAGCAATT-400.2.2 GGCAATTCAGCTCGAC-400.2.2
#> [1,] 4.470893 4.103550
#> [2,] 4.257439 4.231509
#> [3,] 4.041397 4.117604
#> [4,] 4.032342 4.121302
#> [5,] 4.957309 5.267012
#> [6,] 4.754204 4.335059
#> [7,] 4.659767 4.728550
#> [8,] 4.652005 4.425296
#> [9,] 4.565330 4.076923
#> [10,] 4.184994 4.022929
#> [11,] 4.508409 4.085059
#> [12,] 4.494179 4.125740
#> [13,] 4.192755 4.425296
#> [14,] 4.335058 4.541420
#> [15,] 4.328590 3.846154
#> [16,] 4.926261 4.190828
#> GGCAATTTCTGTCCGT-400.2.2 GGCCGATAGGCTAGAC-400.2.2
#> [1,] 4.154828 4.206478
#> [2,] 4.338513 4.218623
#> [3,] 4.338513 4.248313
#> [4,] 4.258047 4.080972
#> [5,] 4.676471 4.441296
#> [6,] 4.411210 4.410256
#> [7,] 4.104329 4.304993
#> [8,] 4.885683 4.846154
#> [9,] 4.815760 4.333333
#> [10,] 4.203108 4.309042
#> [11,] 4.197003 4.318489
#> [12,] 4.310211 4.450742
#> [13,] 4.521643 4.207827
#> [14,] 4.250277 4.287449
#> [15,] 4.007769 4.412955
#> [16,] 4.451720 4.781377
#> GGCCGATCACATGGGA-400.2.2 GGCCGATGTAAGAGGA-400.2.2
#> [1,] 4.004032 4.648970
#> [2,] 4.734879 4.164818
#> [3,] 4.133065 4.587956
#> [4,] 4.254032 3.940571
#> [5,] 4.795363 5.122821
#> [6,] 4.400202 5.093502
#> [7,] 4.403226 4.224247
#> [8,] 4.983871 4.472266
#> [9,] 4.561492 4.645800
#> [10,] 4.145161 4.483360
#> [11,] 4.532258 4.474643
#> [12,] 4.651210 4.451664
#> [13,] 4.157258 3.923138
#> [14,] 4.258065 4.279715
#> [15,] 4.545363 4.316957
#> [16,] 4.821573 4.675911
#> GGCTCGACAATCGAAA-400.2.2 GGCTCGACATGTTGAC-400.2.2
#> [1,] 4.744706 4.312977
#> [2,] 3.735882 4.193021
#> [3,] 4.340000 3.955289
#> [4,] 4.203529 4.232279
#> [5,] 4.681765 4.384951
#> [6,] 4.107647 4.206107
#> [7,] 4.481176 4.477644
#> [8,] 4.458235 4.728462
#> [9,] 3.950000 4.351145
#> [10,] 3.812353 4.229008
#> [11,] 4.561765 4.426390
#> [12,] 4.381765 4.417666
#> [13,] 4.184706 4.774264
#> [14,] 3.921765 4.064340
#> [15,] 3.934118 4.049073
#> [16,] 4.054118 4.454744
#> GGCTGGTGTGCCTGCA-400.2.2 GGCTGGTTCTTTAGGG-400.2.2
#> [1,] 3.924561 4.171141
#> [2,] 3.803686 4.354027
#> [3,] 3.801972 4.364094
#> [4,] 4.038577 4.104027
#> [5,] 5.624089 4.121644
#> [6,] 4.003429 4.143456
#> [7,] 5.164595 4.406879
#> [8,] 4.549078 4.666946
#> [9,] 3.982855 4.682047
#> [10,] 3.766824 4.423658
#> [11,] 4.044578 4.501678
#> [12,] 3.857694 4.625000
#> [13,] 4.021432 4.286074
#> [14,] 4.364766 4.500000
#> [15,] 3.745821 4.674497
#> [16,] 3.944278 4.541946
#> GGGAATGAGACAAGCC-400.2.2 GGGAGATGTACAGCAG-400.2.2
#> [1,] 4.313976 3.982206
#> [2,] 4.281496 4.599051
#> [3,] 4.389764 4.287070
#> [4,] 4.597441 4.003559
#> [5,] 4.780512 4.488731
#> [6,] 4.547244 4.167260
#> [7,] 4.525591 4.194543
#> [8,] 5.096457 4.907473
#> [9,] 4.933071 4.501779
#> [10,] 4.759843 4.115065
#> [11,] 4.240157 4.398577
#> [12,] 4.828740 4.374852
#> [13,] 4.111220 4.276394
#> [14,] 4.486220 4.680902
#> [15,] 4.174213 3.939502
#> [16,] 4.439961 4.437722
#> GGGCACTGTCAAAGAT-400.2.2 GGGTCTGAGTTTAGGA-400.2.2
#> [1,] 4.330849 4.197949
#> [2,] 4.010894 4.527179
#> [3,] 4.025803 3.855385
#> [4,] 4.438073 4.040000
#> [5,] 4.612385 4.431795
#> [6,] 3.938073 4.595897
#> [7,] 4.821674 4.504615
#> [8,] 4.427752 4.913846
#> [9,] 4.173165 4.563077
#> [10,] 3.916284 4.487179
#> [11,] 3.970757 4.801026
#> [12,] 3.987959 4.551795
#> [13,] 4.226491 4.227692
#> [14,] 3.931766 4.077949
#> [15,] 3.909977 3.895385
#> [16,] 4.122706 4.629744
#> GGGTCTGGTATATCCG-400.2.2 GGGTCTGGTCATATGC-400.2.2
#> [1,] 4.584906 4.423927
#> [2,] 4.441509 4.338101
#> [3,] 4.465094 4.299090
#> [4,] 4.326415 3.946684
#> [5,] 5.011321 4.537061
#> [6,] 4.364151 4.669701
#> [7,] 4.521698 4.085826
#> [8,] 4.539623 4.776333
#> [9,] 4.503774 4.618986
#> [10,] 4.481132 4.288687
#> [11,] 4.583019 4.205462
#> [12,] 4.383962 4.455137
#> [13,] 4.249057 4.538362
#> [14,] 4.426415 4.137841
#> [15,] 4.382075 4.139142
#> [16,] 4.334906 4.681404
#> GGGTTGCAGAGCCCAA-400.2.2 GGGTTGCCAAGCTGAG-400.2.2
#> [1,] 4.560881 4.231621
#> [2,] 3.923575 4.256798
#> [3,] 3.994819 4.307150
#> [4,] 4.016839 4.461229
#> [5,] 4.488342 4.332326
#> [6,] 4.563472 4.163142
#> [7,] 4.220207 4.106747
#> [8,] 4.918394 4.663646
#> [9,] 4.663212 4.608258
#> [10,] 4.165803 4.452165
#> [11,] 4.335492 4.128902
#> [12,] 4.567358 4.624371
#> [13,] 4.647668 4.564955
#> [14,] 4.079016 4.171198
#> [15,] 4.329016 4.065458
#> [16,] 4.959845 4.750252
#> GGTATTGAGGCGACAT-400.2.2 GGTATTGGTATAAACG-400.2.2
#> [1,] 4.218638 4.506244
#> [2,] 4.341398 4.253602
#> [3,] 4.229391 4.359270
#> [4,] 4.097670 4.113353
#> [5,] 4.678315 5.151777
#> [6,] 3.875448 4.721422
#> [7,] 4.474014 4.484150
#> [8,] 4.740143 5.223823
#> [9,] 4.455197 4.699328
#> [10,] 4.137097 4.163305
#> [11,] 4.640681 4.615754
#> [12,] 4.867384 4.435159
#> [13,] 4.501792 4.381364
#> [14,] 4.091398 4.136407
#> [15,] 4.289427 4.180596
#> [16,] 4.421147 4.612872
#> GGTATTGGTCGTCTTC-400.2.2 GGTGAAGGTGCTTCTC-400.2.2
#> [1,] 4.245353 4.160729
#> [2,] 4.237918 4.253521
#> [3,] 4.151177 3.848384
#> [4,] 4.111524 3.984258
#> [5,] 4.251549 5.123447
#> [6,] 4.159851 4.091964
#> [7,] 4.194548 5.005800
#> [8,] 4.717472 4.712510
#> [9,] 4.111524 4.109362
#> [10,] 4.261462 3.875725
#> [11,] 4.366791 4.207125
#> [12,] 4.334572 4.051367
#> [13,] 4.275093 4.013256
#> [14,] 4.168525 4.463132
#> [15,] 4.209418 3.841756
#> [16,] 4.568773 3.879039
#> GGTGTTACAGCCTTGG-400.2.2 GGTGTTATCTGCTTGC-400.2.2
#> [1,] 4.450179 4.550476
#> [2,] 4.248746 3.813333
#> [3,] 4.278136 4.144762
#> [4,] 3.944803 4.263810
#> [5,] 4.886022 4.890476
#> [6,] 4.714695 4.045714
#> [7,] 4.539785 4.693333
#> [8,] 4.789964 4.417143
#> [9,] 4.681004 4.175238
#> [10,] 4.296057 3.851429
#> [11,] 4.704659 4.315238
#> [12,] 4.527599 4.188571
#> [13,] 3.843011 4.057143
#> [14,] 4.127599 4.320952
#> [15,] 3.977778 3.822857
#> [16,] 4.536201 4.366667
#> GTACTCCTCACCGGGT-400.2.2 GTACTTTCATCGTCGG-400.2.2
#> [1,] 4.054374 4.590342
#> [2,] 4.399527 3.862662
#> [3,] 4.268322 4.094464
#> [4,] 4.028369 4.087161
#> [5,] 4.322695 4.811307
#> [6,] 4.028369 4.171731
#> [7,] 4.063830 4.649470
#> [8,] 5.079196 4.364664
#> [9,] 4.377069 4.323439
#> [10,] 4.147754 3.777385
#> [11,] 4.424350 4.512132
#> [12,] 4.203310 4.102473
#> [13,] 4.444444 4.404240
#> [14,] 4.270686 4.056773
#> [15,] 3.858156 4.093522
#> [16,] 4.569740 4.068787
#> GTACTTTGTAGCGTCC-400.2.2 GTATCTTAGCCGGTAA-400.2.2
#> [1,] 4.626474 4.338248
#> [2,] 4.041940 4.350390
#> [3,] 4.335518 4.254987
#> [4,] 4.435125 4.352125
#> [5,] 4.765400 4.800520
#> [6,] 4.062910 4.524718
#> [7,] 4.494102 4.241977
#> [8,] 4.321101 4.812663
#> [9,] 4.445609 4.389419
#> [10,] 4.069463 4.724198
#> [11,] 4.162516 4.430182
#> [12,] 4.107471 4.446661
#> [13,] 3.909567 4.281873
#> [14,] 4.452163 4.275802
#> [15,] 4.011796 4.207285
#> [16,] 4.344692 4.341717
#> GTATCTTGTACTCTCC-400.2.2 GTATCTTGTTTAAGCC-400.2.2
#> [1,] 4.721583 4.771593
#> [2,] 4.057554 3.664747
#> [3,] 4.212230 4.218170
#> [4,] 4.153237 4.218170
#> [5,] 4.639568 4.665387
#> [6,] 4.176259 4.067818
#> [7,] 4.102158 4.628279
#> [8,] 4.858273 4.371721
#> [9,] 3.806475 4.112604
#> [10,] 3.944604 3.937300
#> [11,] 4.323741 4.384517
#> [12,] 4.115827 4.178503
#> [13,] 4.233813 4.284069
#> [14,] 3.874101 4.157390
#> [15,] 4.096403 4.035829
#> [16,] 4.276978 4.129239
#> GTATTCTGTCAGTGGA-400.2.2 GTCAAGTCACCAGCAC-400.2.2
#> [1,] 4.458333 4.196341
#> [2,] 4.068750 4.218293
#> [3,] 4.175000 4.147561
#> [4,] 3.723611 4.257317
#> [5,] 4.843056 4.562195
#> [6,] 4.157639 4.479268
#> [7,] 5.127778 4.496341
#> [8,] 4.339583 4.464634
#> [9,] 3.966667 4.873171
#> [10,] 3.872222 4.431707
#> [11,] 4.168056 4.502439
#> [12,] 3.934722 4.276829
#> [13,] 4.254167 4.121951
#> [14,] 4.261806 4.118293
#> [15,] 4.229861 3.748780
#> [16,] 4.114583 4.601220
#> GTCACAAAGTGTTAGA-400.2.2 GTCACAATCAGAGCTT-400.2.2
#> [1,] 4.234727 4.044527
#> [2,] 4.228296 4.007421
#> [3,] 4.166131 4.476809
#> [4,] 4.615220 4.052876
#> [5,] 4.613076 4.564935
#> [6,] 4.071811 4.455473
#> [7,] 4.588424 3.885900
#> [8,] 4.587353 4.794991
#> [9,] 4.266881 4.656772
#> [10,] 4.443730 4.356215
#> [11,] 4.591640 4.256957
#> [12,] 4.355841 4.599258
#> [13,] 4.549839 4.179035
#> [14,] 3.982851 4.056586
#> [15,] 4.032154 4.354360
#> [16,] 4.512326 4.741187
#> GTCACAATCATCTGTT-400.2.2 GTCATTTAGAGGGATA-400.2.2
#> [1,] 4.482054 4.246240
#> [2,] 3.738861 4.331878
#> [3,] 4.027228 4.100194
#> [4,] 4.298267 4.221494
#> [5,] 5.022896 4.827754
#> [6,] 4.294554 4.211305
#> [7,] 4.535891 4.929403
#> [8,] 4.543936 4.473557
#> [9,] 4.255569 4.232169
#> [10,] 3.943688 4.243814
#> [11,] 3.886757 4.312955
#> [12,] 4.243812 4.040272
#> [13,] 4.187500 4.169335
#> [14,] 4.123144 4.644833
#> [15,] 3.761757 3.981320
#> [16,] 4.225866 4.084425
#> GTCATTTGTATTACCG-400.2.2 GTCATTTTCTTAGAGC-400.2.2
#> [1,] 4.316526 4.114801
#> [2,] 3.937866 3.629603
#> [3,] 3.869226 3.840794
#> [4,] 4.233247 4.312635
#> [5,] 5.357515 5.660289
#> [6,] 4.188029 4.050181
#> [7,] 5.084255 5.075812
#> [8,] 4.169486 4.009386
#> [9,] 4.126220 3.894224
#> [10,] 4.214704 3.933935
#> [11,] 4.124268 4.049097
#> [12,] 4.173064 4.009025
#> [13,] 4.362069 4.356318
#> [14,] 4.367274 4.267148
#> [15,] 3.872154 3.742960
#> [16,] 3.987964 3.981949
#> GTCGGGTTCACCGTAA-400.2.2 GTCGGGTTCGGATGGA-400.2.2
#> [1,] 4.435075 4.264411
#> [2,] 3.672388 4.438596
#> [3,] 3.934328 4.364662
#> [4,] 3.934328 4.076441
#> [5,] 5.337313 4.474937
#> [6,] 3.864179 4.350877
#> [7,] 4.995522 4.206767
#> [8,] 4.120896 4.773183
#> [9,] 3.938806 5.007519
#> [10,] 3.798507 4.308271
#> [11,] 4.064925 4.522556
#> [12,] 4.017164 4.802005
#> [13,] 4.357463 4.363409
#> [14,] 4.318657 4.023810
#> [15,] 4.240299 3.843358
#> [16,] 4.517164 4.884712
#> GTGCAGCCACTTGGAT-400.2.2 GTGCAGCTCAAACAAG-400.2.2
#> [1,] 4.290365 4.418200
#> [2,] 4.050130 4.199387
#> [3,] 4.055339 3.997955
#> [4,] 4.164062 4.224949
#> [5,] 5.216797 4.483640
#> [6,] 4.116536 4.411043
#> [7,] 4.742188 4.209611
#> [8,] 4.198568 4.696319
#> [9,] 4.059896 4.639059
#> [10,] 3.942057 4.302658
#> [11,] 3.990234 4.147239
#> [12,] 3.912760 4.438650
#> [13,] 4.207682 4.183027
#> [14,] 4.244792 4.111452
#> [15,] 4.133464 3.949898
#> [16,] 4.046224 4.793456
#> GTGCAGCTCGCGTAGC-400.2.2 GTGCATACACGGTGTC-400.2.2
#> [1,] 4.356293 4.295553
#> [2,] 4.265498 4.308540
#> [3,] 4.233563 4.347501
#> [4,] 4.206637 4.364817
#> [5,] 4.503444 4.809721
#> [6,] 4.275517 4.304408
#> [7,] 4.465874 4.952774
#> [8,] 4.541014 4.229634
#> [9,] 4.385723 4.135773
#> [10,] 4.239198 4.301456
#> [11,] 4.356919 4.407910
#> [12,] 4.185348 4.174734
#> [13,] 4.150282 4.370720
#> [14,] 4.502192 4.371507
#> [15,] 4.088291 4.132822
#> [16,] 4.285535 4.251476
#> GTGCGGTCAAATCCGT-400.2.2 GTGCGGTTCTGGAGCC-400.2.2
#> [1,] 4.548428 4.215087
#> [2,] 4.236478 4.205912
#> [3,] 4.123270 4.428135
#> [4,] 4.249057 4.486239
#> [5,] 4.281761 4.825688
#> [6,] 4.406289 4.307849
#> [7,] 4.230189 4.214067
#> [8,] 4.304403 4.681957
#> [9,] 4.410063 4.264016
#> [10,] 4.220126 4.083588
#> [11,] 4.324528 4.436290
#> [12,] 4.461635 4.146789
#> [13,] 4.549686 4.331295
#> [14,] 4.534591 4.025484
#> [15,] 4.149686 4.447503
#> [16,] 4.955975 4.408767
#> GTGCTTCGTGATGATA-400.2.2 GTGCTTCGTTGTGGCC-400.2.2
#> [1,] 4.058423 4.857567
#> [2,] 4.435248 3.715134
#> [3,] 4.279455 3.791543
#> [4,] 4.046738 4.291543
#> [5,] 4.232717 5.259644
#> [6,] 3.967868 3.821958
#> [7,] 4.378773 4.397626
#> [8,] 5.178189 4.437685
#> [9,] 4.415774 4.063056
#> [10,] 4.538462 3.864243
#> [11,] 4.703992 3.894659
#> [12,] 4.305745 4.109792
#> [13,] 4.260954 4.011869
#> [14,] 4.307692 3.976261
#> [15,] 4.043817 4.214392
#> [16,] 4.632911 4.549703
#> GTGTGCGAGCCAACAG-400.2.2 GTGTGCGAGCTGGAAC-400.2.2
#> [1,] 4.387043 4.761364
#> [2,] 4.021595 3.947240
#> [3,] 4.117110 4.090909
#> [4,] 3.896179 4.269481
#> [5,] 4.806478 5.001623
#> [6,] 4.003322 4.014610
#> [7,] 4.528239 4.932630
#> [8,] 4.475083 4.206981
#> [9,] 4.358804 4.333604
#> [10,] 4.240033 3.808442
#> [11,] 4.033223 4.162338
#> [12,] 4.037375 3.957792
#> [13,] 4.671096 4.322240
#> [14,] 4.252492 4.292208
#> [15,] 4.111296 3.771104
#> [16,] 4.450997 4.068994
#> GTGTGCGTCCGCAAGC-400.2.2 GTGTGCGTCGAATCCA-400.2.2
#> [1,] 4.482270 4.409524
#> [2,] 4.119681 4.479762
#> [3,] 4.587766 4.533333
#> [4,] 4.315603 4.250000
#> [5,] 4.337766 4.697619
#> [6,] 4.312943 4.342857
#> [7,] 4.288121 4.148810
#> [8,] 4.946809 4.960714
#> [9,] 4.476950 4.596429
#> [10,] 4.351950 4.052381
#> [11,] 4.274823 4.351190
#> [12,] 4.714539 4.364286
#> [13,] 4.232270 4.580952
#> [14,] 4.146277 4.279762
#> [15,] 4.500887 4.311905
#> [16,] 4.396277 4.802381
#> GTGTGCGTCTTGACGA-400.2.2 GTGTTAGAGACGCTTT-400.2.2
#> [1,] 4.533915 4.059757
#> [2,] 3.802326 4.098488
#> [3,] 3.928295 4.295832
#> [4,] 3.943798 4.041129
#> [5,] 4.975775 4.693102
#> [6,] 3.863372 3.952969
#> [7,] 4.618217 4.623202
#> [8,] 4.365310 4.397639
#> [9,] 4.105620 4.362228
#> [10,] 3.843992 4.039838
#> [11,] 4.152132 4.151973
#> [12,] 3.854651 4.340649
#> [13,] 4.098837 4.381409
#> [14,] 4.371124 4.314644
#> [15,] 3.919574 4.127444
#> [16,] 4.550388 4.271302
#> GTGTTAGCACCTCGTT-400.2.2 GTGTTAGCATGGGACA-400.2.2
#> [1,] 4.195504 4.590664
#> [2,] 4.263624 4.091562
#> [3,] 4.500000 3.967684
#> [4,] 4.072207 4.278276
#> [5,] 4.638965 5.088869
#> [6,] 4.059264 4.133752
#> [7,] 4.619210 4.555655
#> [8,] 4.557902 4.525135
#> [9,] 4.170300 4.360862
#> [10,] 3.959809 3.967684
#> [11,] 4.301771 3.952424
#> [12,] 4.532698 4.523339
#> [13,] 4.138965 4.271095
#> [14,] 4.213896 4.248654
#> [15,] 4.236376 4.109515
#> [16,] 4.409401 4.283662
#> GTTAAGCAGGAACTGC-400.2.2 GTTAAGCCATTGTGCA-400.2.2
#> [1,] 4.290413 4.246452
#> [2,] 4.544437 4.414194
#> [3,] 4.111267 4.095484
#> [4,] 3.877537 3.957419
#> [5,] 4.936319 4.623226
#> [6,] 4.172848 4.419355
#> [7,] 4.093072 4.179355
#> [8,] 4.791463 5.036129
#> [9,] 4.500350 4.754839
#> [10,] 4.095171 4.276129
#> [11,] 4.167250 4.205161
#> [12,] 4.430371 4.601290
#> [13,] 4.491253 4.545806
#> [14,] 4.155353 4.410323
#> [15,] 3.710287 4.504516
#> [16,] 4.520644 4.387097
#> GTTAAGCGTAGCTAAA-400.2.2 GTTAAGCTCATGTCCC-400.2.2
#> [1,] 4.556841 4.409333
#> [2,] 3.747447 4.393333
#> [3,] 4.118448 4.300000
#> [4,] 4.399592 4.289333
#> [5,] 5.154527 4.824000
#> [6,] 3.773315 4.314667
#> [7,] 4.835262 4.497333
#> [8,] 4.543227 4.908000
#> [9,] 4.078965 4.284000
#> [10,] 3.701157 4.493333
#> [11,] 4.224643 4.210667
#> [12,] 4.030633 4.648000
#> [13,] 4.176310 4.198667
#> [14,] 4.281824 4.485333
#> [15,] 3.900613 4.317333
#> [16,] 4.452689 4.696000
#> GTTACAGGTAGTAGTA-400.2.2 GTTCATTAGATAGGAG-400.2.2
#> [1,] 4.591017 4.347090
#> [2,] 3.806041 4.317460
#> [3,] 4.326312 4.492063
#> [4,] 4.216216 4.346032
#> [5,] 5.023847 4.268783
#> [6,] 3.838235 4.277249
#> [7,] 4.611288 4.386243
#> [8,] 4.275437 4.524868
#> [9,] 4.081081 4.911111
#> [10,] 3.964229 4.110053
#> [11,] 4.121224 4.491005
#> [12,] 4.334658 4.643386
#> [13,] 4.238076 4.410582
#> [14,] 4.131161 4.264550
#> [15,] 4.135930 4.134392
#> [16,] 4.154610 4.550265
#> GTTCATTTCAGCTCGG-400.2.2 GTTCGGGAGAGGTTAT-400.2.2
#> [1,] 4.538824 4.562727
#> [2,] 4.554118 3.545455
#> [3,] 4.455294 3.965152
#> [4,] 4.270588 4.164545
#> [5,] 4.504706 5.098182
#> [6,] 4.312941 3.780606
#> [7,] 4.000000 4.952121
#> [8,] 4.849412 4.306970
#> [9,] 4.467059 4.239697
#> [10,] 4.378824 3.791515
#> [11,] 4.094118 4.161212
#> [12,] 4.310588 4.044242
#> [13,] 4.354118 4.040909
#> [14,] 4.047059 4.231212
#> [15,] 4.322353 3.831515
#> [16,] 4.465882 3.793030
#> GTTCTCGAGAGCTGCA-400.2.2 GTTCTCGAGGCAGTCA-400.2.2
#> [1,] 4.256257 4.800595
#> [2,] 4.176400 3.623512
#> [3,] 4.282479 3.837798
#> [4,] 4.271752 4.526290
#> [5,] 4.947557 5.038690
#> [6,] 4.449344 3.977183
#> [7,] 3.955900 4.819940
#> [8,] 4.884386 4.424603
#> [9,] 4.606675 4.206349
#> [10,] 4.507747 3.844246
#> [11,] 4.436234 3.879960
#> [12,] 4.504172 4.013393
#> [13,] 4.569726 4.293155
#> [14,] 4.034565 4.062500
#> [15,] 3.882002 3.866071
#> [16,] 4.466031 4.066964
#> GTTCTCGTCCCTGACT-400.2.2 TAAACCGAGCGCCTCA-400.2.2
#> [1,] 4.506718 4.246883
#> [2,] 3.985925 4.142145
#> [3,] 3.939859 4.104738
#> [4,] 3.912988 4.322943
#> [5,] 4.962892 4.466334
#> [6,] 3.955854 4.319202
#> [7,] 4.095969 4.451372
#> [8,] 4.368522 4.825436
#> [9,] 4.058221 4.486284
#> [10,] 4.024952 4.236908
#> [11,] 4.341651 4.456359
#> [12,] 4.146513 4.457606
#> [13,] 4.355086 4.281796
#> [14,] 4.316059 4.289277
#> [15,] 4.143314 4.167082
#> [16,] 4.611644 4.162095
#> TAAGCGTCAATGGATA-400.2.2 TAAGTGCAGACGCACA-400.2.2
#> [1,] 4.349333 4.340336
#> [2,] 4.262667 3.654622
#> [3,] 4.060000 3.976471
#> [4,] 4.330667 4.418487
#> [5,] 4.436000 5.403361
#> [6,] 4.044000 4.105042
#> [7,] 4.113333 5.136975
#> [8,] 4.624000 4.170588
#> [9,] 4.005333 3.997479
#> [10,] 4.361333 3.615126
#> [11,] 4.149333 4.173109
#> [12,] 4.570667 4.048739
#> [13,] 4.653333 4.102521
#> [14,] 4.466667 4.210084
#> [15,] 4.430667 3.847059
#> [16,] 5.005333 3.764706
#> TAAGTGCAGATCCCGC-400.2.2 TAAGTGCAGGCTAGAC-400.2.2
#> [1,] 4.450626 4.432797
#> [2,] 4.136648 3.801286
#> [3,] 4.327886 4.053055
#> [4,] 4.279903 4.144051
#> [5,] 4.906815 5.240836
#> [6,] 4.027121 3.963666
#> [7,] 4.476356 4.868489
#> [8,] 4.501391 4.286817
#> [9,] 4.115438 4.257878
#> [10,] 3.912031 3.890032
#> [11,] 4.183936 4.176206
#> [12,] 4.355007 4.239550
#> [13,] 4.255563 4.025402
#> [14,] 4.245132 4.249839
#> [15,] 4.207232 3.963344
#> [16,] 4.433936 4.216077
#> TAAGTGCGTACTCGCG-400.2.2 TAAGTGCGTCGGCACT-400.2.2
#> [1,] 4.643649 4.869764
#> [2,] 4.594203 3.426504
#> [3,] 4.158568 3.845392
#> [4,] 4.199488 4.275704
#> [5,] 4.849105 5.191165
#> [6,] 4.409207 3.765423
#> [7,] 4.445865 4.944402
#> [8,] 4.693095 4.054075
#> [9,] 4.757033 4.358720
#> [10,] 4.221654 3.712110
#> [11,] 4.093777 3.772277
#> [12,] 4.627451 3.812643
#> [13,] 4.297528 4.456207
#> [14,] 4.219096 4.597106
#> [15,] 4.167093 3.850724
#> [16,] 4.780904 3.942879
#> TAAGTGCGTGGTCTCG-400.2.2 TAAGTGCTCCATTCTA-400.2.2
#> [1,] 4.374713 4.547063
#> [2,] 4.229885 4.031847
#> [3,] 4.354023 4.043878
#> [4,] 4.013793 4.025478
#> [5,] 4.624138 4.707006
#> [6,] 4.249425 4.135881
#> [7,] 4.113793 4.538570
#> [8,] 4.910345 4.546355
#> [9,] 4.402299 4.421798
#> [10,] 4.435632 4.245577
#> [11,] 4.147126 4.177636
#> [12,] 4.397701 4.197452
#> [13,] 4.625287 4.234961
#> [14,] 4.136782 4.402689
#> [15,] 4.108046 4.117481
#> [16,] 4.480460 4.237792
#> TACACGAGTGGTCTCG-400.2.2 TACAGTGGTAGAAAGG-400.2.2
#> [1,] 4.273042 4.101980
#> [2,] 4.497574 4.579208
#> [3,] 4.183645 4.290099
#> [4,] 4.233541 4.114851
#> [5,] 4.575884 4.893069
#> [6,] 4.092169 4.129703
#> [7,] 4.415800 4.527723
#> [8,] 4.776854 4.856436
#> [9,] 4.319473 4.507921
#> [10,] 4.460152 4.641584
#> [11,] 4.321552 4.211881
#> [12,] 4.760915 4.707921
#> [13,] 4.725572 4.136634
#> [14,] 4.161469 4.173267
#> [15,] 4.593209 4.427723
#> [16,] 4.417186 4.255446
#> TACCTATAGTACGCCC-400.2.2 TACCTATGTGCGCTTG-400.2.2
#> [1,] 4.389667 4.656434
#> [2,] 4.066112 4.395514
#> [3,] 4.255692 4.015348
#> [4,] 4.193082 4.138135
#> [5,] 4.764448 4.593861
#> [6,] 4.243433 4.583235
#> [7,] 4.611646 4.158205
#> [8,] 4.488179 4.876033
#> [9,] 4.305166 4.531287
#> [10,] 4.144046 4.441558
#> [11,] 3.965849 4.324675
#> [12,] 4.498249 4.513577
#> [13,] 4.620403 4.493506
#> [14,] 4.212785 4.337662
#> [15,] 4.480736 4.096812
#> [16,] 4.340193 4.911452
#> TACCTATTCGCCAAAT-400.2.2 TACCTTACAACACGCC-400.2.2
#> [1,] 4.283197 4.374665
#> [2,] 4.237256 3.851026
#> [3,] 4.275645 4.206958
#> [4,] 4.120201 4.377342
#> [5,] 4.809314 4.836753
#> [6,] 3.884204 4.018733
#> [7,] 4.597860 4.613738
#> [8,] 4.360604 4.432649
#> [9,] 4.409062 4.157895
#> [10,] 4.216488 4.399643
#> [11,] 4.352423 4.139161
#> [12,] 4.151668 4.234612
#> [13,] 4.302077 4.092774
#> [14,] 4.098804 4.462979
#> [15,] 3.934550 4.115076
#> [16,] 4.657017 4.380018
#> TACGGATCAAAGCAAT-400.2.2 TACGGGCCATCAGTCA-400.2.2
#> [1,] 4.147980 4.323224
#> [2,] 4.462626 4.377816
#> [3,] 4.336364 4.248700
#> [4,] 4.418687 4.028596
#> [5,] 4.397475 4.818024
#> [6,] 4.366162 4.024263
#> [7,] 4.186869 4.194107
#> [8,] 5.008081 4.734835
#> [9,] 4.675758 4.454073
#> [10,] 4.284343 4.190641
#> [11,] 4.330303 4.167244
#> [12,] 4.582828 4.225303
#> [13,] 4.414646 4.294627
#> [14,] 4.417677 4.233102
#> [15,] 4.128788 4.185442
#> [16,] 4.326768 4.596187
#> TACGGTAAGACATAAC-400.2.2 TACGGTACAAACAACA-400.2.2
#> [1,] 4.350069 4.249499
#> [2,] 4.215956 4.649299
#> [3,] 4.184319 4.029058
#> [4,] 4.460110 3.973948
#> [5,] 4.392710 5.130261
#> [6,] 4.198074 4.584168
#> [7,] 4.649243 4.243487
#> [8,] 4.737964 4.979960
#> [9,] 4.542641 4.281563
#> [10,] 4.436039 4.724449
#> [11,] 4.251719 3.997996
#> [12,] 4.621733 4.747495
#> [13,] 4.484869 4.236473
#> [14,] 4.053645 4.010020
#> [15,] 4.237964 4.040080
#> [16,] 4.309491 4.392786
#> TACGGTACAAGCTGGA-400.2.2 TACGGTAGTCATATGC-400.2.2
#> [1,] 4.509191 4.382173
#> [2,] 3.889706 4.338217
#> [3,] 4.010110 4.098901
#> [4,] 4.054228 3.855922
#> [5,] 4.541360 4.423687
#> [6,] 3.920956 4.153846
#> [7,] 4.187500 4.393162
#> [8,] 4.530331 4.980464
#> [9,] 4.602022 4.669109
#> [10,] 3.738051 4.336996
#> [11,] 4.256434 4.032967
#> [12,] 4.259191 4.307692
#> [13,] 4.358456 4.579976
#> [14,] 4.239890 4.333333
#> [15,] 3.893382 4.223443
#> [16,] 4.182904 4.686203
#> TACGGTATCGGCTTGG-400.2.2 TACTCATCAGCTGCAC-400.2.2
#> [1,] 4.349377 4.340295
#> [2,] 4.130238 4.640049
#> [3,] 4.330125 3.786241
#> [4,] 4.037373 4.299754
#> [5,] 4.758211 4.674447
#> [6,] 3.862967 4.531941
#> [7,] 4.583239 4.219902
#> [8,] 4.462627 4.964373
#> [9,] 4.278029 4.508600
#> [10,] 4.097961 5.028256
#> [11,] 4.271801 4.389435
#> [12,] 4.370328 4.567568
#> [13,] 4.248018 4.496314
#> [14,] 4.396942 4.202703
#> [15,] 4.157984 3.726044
#> [16,] 4.507361 4.168305
#> TACTCGCCACGAAAGC-400.2.2 TACTCGCTCACTATTC-400.2.2
#> [1,] 4.461820 4.301449
#> [2,] 3.847282 4.265700
#> [3,] 4.135614 4.106280
#> [4,] 4.081857 3.815459
#> [5,] 5.144166 4.920773
#> [6,] 3.774588 4.377778
#> [7,] 4.897373 4.323671
#> [8,] 3.868662 4.300483
#> [9,] 4.405009 4.601932
#> [10,] 4.014050 4.342029
#> [11,] 4.293219 4.429952
#> [12,] 3.757483 4.489855
#> [13,] 4.265730 4.299517
#> [14,] 4.458155 4.320773
#> [15,] 3.798412 4.057005
#> [16,] 4.495418 4.678261
#> TACTTGTGTCCGAACC-400.2.2 TAGACCAGTCCAGTTA-400.2.2
#> [1,] 4.659031 4.779927
#> [2,] 3.961387 4.256348
#> [3,] 4.337696 4.324063
#> [4,] 4.134817 4.266022
#> [5,] 4.460733 5.152358
#> [6,] 4.126309 3.889964
#> [7,] 4.609948 4.175333
#> [8,] 4.474476 4.463120
#> [9,] 4.326571 3.868198
#> [10,] 3.888089 4.147521
#> [11,] 4.569372 4.284160
#> [12,] 4.374346 4.094317
#> [13,] 4.178010 3.951632
#> [14,] 4.186518 3.928658
#> [15,] 3.871728 4.553809
#> [16,] 4.126309 5.049577
#> TAGACCATCTATGTGG-400.2.2 TAGAGCTAGCTGCAAG-400.2.2
#> [1,] 4.130648 4.456615
#> [2,] 3.882613 3.785231
#> [3,] 4.056974 4.020308
#> [4,] 4.204813 4.419077
#> [5,] 4.753929 4.606154
#> [6,] 3.946464 3.892923
#> [7,] 4.901768 4.784000
#> [8,] 4.384086 4.551385
#> [9,] 4.090373 4.329231
#> [10,] 3.896857 3.793846
#> [11,] 3.968075 4.179077
#> [12,] 3.811886 3.947077
#> [13,] 4.353143 4.373538
#> [14,] 4.279470 4.367385
#> [15,] 3.830550 3.625231
#> [16,] 4.202849 3.850462
#> TAGAGCTGTACAGTTC-400.2.2 TAGGCATCACCGAAAG-400.2.2
#> [1,] 4.176809 4.168285
#> [2,] 4.208059 3.875944
#> [3,] 4.093750 3.981661
#> [4,] 4.255345 4.163970
#> [5,] 5.137747 4.888350
#> [6,] 4.064556 4.201726
#> [7,] 4.766447 4.792880
#> [8,] 4.418586 4.266451
#> [9,] 4.315378 4.323085
#> [10,] 4.121711 4.135383
#> [11,] 4.321957 4.196332
#> [12,] 4.321546 4.191478
#> [13,] 4.400082 4.415858
#> [14,] 4.219572 4.391046
#> [15,] 3.945724 3.921791
#> [16,] 4.232730 4.245955
#> TAGTTGGCATGCAATC-400.2.2 TAGTTGGGTCATACTG-400.2.2
#> [1,] 4.330966 4.653846
#> [2,] 4.129261 3.846154
#> [3,] 4.465909 4.021277
#> [4,] 4.249290 4.011457
#> [5,] 4.994318 4.927987
#> [6,] 3.990057 3.880524
#> [7,] 4.716619 4.456628
#> [8,] 4.541903 4.427169
#> [9,] 4.320312 4.211948
#> [10,] 3.854403 3.872340
#> [11,] 4.099432 3.938625
#> [12,] 4.205966 3.923895
#> [13,] 4.426136 4.430442
#> [14,] 4.150568 4.400982
#> [15,] 4.007812 3.956628
#> [16,] 4.298295 4.260229
#> TAGTTGGTCAACACAC-400.2.2 TATCTCAAGTGACATA-400.2.2
#> [1,] 4.207303 4.311111
#> [2,] 4.346629 3.909259
#> [3,] 4.205618 3.983951
#> [4,] 4.379775 4.185802
#> [5,] 4.503371 4.602469
#> [6,] 4.298315 3.882716
#> [7,] 4.271348 4.464198
#> [8,] 4.910112 4.638272
#> [9,] 4.602247 4.262346
#> [10,] 4.295506 4.350617
#> [11,] 4.474719 3.941358
#> [12,] 4.578652 4.322222
#> [13,] 4.446067 4.432716
#> [14,] 4.003371 4.234568
#> [15,] 4.239326 3.945679
#> [16,] 4.391011 4.408025
#> TATGCCCCAATGGACG-400.2.2 TATGCCCCACAGGTTT-400.2.2
#> [1,] 4.464206 4.642750
#> [2,] 4.215884 3.587444
#> [3,] 4.242170 3.672646
#> [4,] 3.999441 4.160688
#> [5,] 4.519016 5.855007
#> [6,] 4.203579 3.597160
#> [7,] 4.280201 5.159940
#> [8,] 4.521812 3.899103
#> [9,] 4.419463 3.760090
#> [10,] 4.284116 3.547085
#> [11,] 4.270694 3.912556
#> [12,] 4.638702 3.882661
#> [13,] 4.458054 4.194320
#> [14,] 4.203579 4.303438
#> [15,] 4.438479 3.867713
#> [16,] 4.647092 4.107623
#> TATTACCGTTGGTGGA-400.2.2 TCAACGATCACGAAGG-400.2.2
#> [1,] 4.455682 4.303188
#> [2,] 4.293182 3.897391
#> [3,] 4.196591 4.333913
#> [4,] 4.248864 4.150145
#> [5,] 4.582955 4.424928
#> [6,] 4.369318 4.099710
#> [7,] 4.210227 4.579710
#> [8,] 4.756818 4.357101
#> [9,] 4.801136 4.498551
#> [10,] 4.115909 3.936232
#> [11,] 4.111364 4.060290
#> [12,] 4.279545 4.274783
#> [13,] 4.540909 4.126377
#> [14,] 3.945455 4.474783
#> [15,] 4.075000 4.407536
#> [16,] 4.487500 4.025507
#> TCAATCTCACCGAAAG-400.2.2 TCAATCTCACTTAACG-400.2.2
#> [1,] 4.463145 4.600257
#> [2,] 3.880835 3.794987
#> [3,] 3.660934 4.147172
#> [4,] 3.874693 4.288560
#> [5,] 5.385749 4.893959
#> [6,] 3.724816 3.977506
#> [7,] 4.979115 4.934447
#> [8,] 4.138821 4.386247
#> [9,] 3.641278 3.969152
#> [10,] 3.721130 4.038560
#> [11,] 3.875921 4.104756
#> [12,] 3.710074 4.136889
#> [13,] 3.970516 4.219152
#> [14,] 4.055283 4.163239
#> [15,] 4.260442 3.759640
#> [16,] 4.514742 4.197943
#> TCACAAGTCATCGATG-400.2.2 TCAGCAAAGATGCCTT-400.2.2
#> [1,] 4.063455 4.336421
#> [2,] 4.448884 3.679158
#> [3,] 4.280846 3.942737
#> [4,] 4.063455 4.018105
#> [5,] 4.105758 4.995368
#> [6,] 4.319624 4.349474
#> [7,] 4.246769 4.902316
#> [8,] 4.794360 3.999579
#> [9,] 4.956522 4.210947
#> [10,] 4.848414 4.033684
#> [11,] 4.144536 3.954526
#> [12,] 4.687427 3.845474
#> [13,] 4.719154 4.080000
#> [14,] 4.305523 4.286737
#> [15,] 4.534665 3.879579
#> [16,] 4.200940 4.236632
#> TCAGCAAGTATGGTTC-400.2.2 TCAGCTCTCAACACAC-400.2.2
#> [1,] 4.349682 4.115353
#> [2,] 4.154405 3.973444
#> [3,] 4.256131 3.968465
#> [4,] 4.267030 4.039834
#> [5,] 4.635786 4.512863
#> [6,] 4.138056 4.016598
#> [7,] 4.512262 4.522822
#> [8,] 4.783833 4.410788
#> [9,] 4.663942 4.159336
#> [10,] 4.376930 4.186722
#> [11,] 4.366939 3.796680
#> [12,] 4.441417 3.936929
#> [13,] 4.304269 4.365145
#> [14,] 4.178020 4.115353
#> [15,] 4.063579 4.026556
#> [16,] 4.231608 4.374274
#> TCAGGTATCGAACTGT-400.2.2 TCATTTGGTCTCTTAT-400.2.2
#> [1,] 4.225699 4.309942
#> [2,] 4.448069 4.153996
#> [3,] 4.364181 4.198830
#> [4,] 4.140479 4.155945
#> [5,] 4.802929 4.426901
#> [6,] 4.197736 4.088694
#> [7,] 4.347537 4.676413
#> [8,] 4.796272 4.633528
#> [9,] 4.366844 4.608187
#> [10,] 4.115846 4.078947
#> [11,] 4.036618 4.131579
#> [12,] 4.441411 4.257310
#> [13,] 4.423435 4.862573
#> [14,] 4.063249 4.116959
#> [15,] 4.105859 4.377193
#> [16,] 4.442077 4.466862
#> TCGAGGCGTAGCGATG-400.2.2 TCGAGGCGTTTGCATG-400.2.2
#> [1,] 4.534323 4.538105
#> [2,] 3.812616 3.963552
#> [3,] 3.863946 3.781975
#> [4,] 4.320346 3.977469
#> [5,] 5.042053 5.370444
#> [6,] 3.952381 3.549370
#> [7,] 5.006184 4.491716
#> [8,] 4.147186 4.610338
#> [9,] 3.922696 4.155732
#> [10,] 3.829932 3.718357
#> [11,] 3.760049 4.182903
#> [12,] 3.862090 3.730285
#> [13,] 4.060606 3.874751
#> [14,] 4.262832 4.750166
#> [15,] 3.738404 3.731610
#> [16,] 4.082870 4.133863
#> TCGCGAGGTTATCCGA-400.2.2 TCGCGAGTCTTGTACT-400.2.2
#> [1,] 4.534308 4.465075
#> [2,] 3.961755 4.083996
#> [3,] 4.275028 4.175950
#> [4,] 4.292463 3.998232
#> [5,] 4.541057 4.711760
#> [6,] 4.192913 4.427056
#> [7,] 4.073678 4.262599
#> [8,] 4.779528 4.475685
#> [9,] 4.569741 4.386384
#> [10,] 4.276153 4.513705
#> [11,] 4.084364 4.274094
#> [12,] 4.437008 4.435897
#> [13,] 4.347019 4.385500
#> [14,] 4.298650 4.454465
#> [15,] 4.073678 4.136163
#> [16,] 4.239595 4.021220
#> TCGCGTTAGGCTCTTA-400.2.2 TCGGGACCAGATAATG-400.2.2
#> [1,] 4.515823 4.377863
#> [2,] 4.300633 4.404580
#> [3,] 4.186709 4.356870
#> [4,] 4.608650 4.250000
#> [5,] 4.847046 4.816794
#> [6,] 4.650844 4.500000
#> [7,] 4.112869 4.421756
#> [8,] 5.149789 4.848282
#> [9,] 4.879747 4.609733
#> [10,] 4.401899 4.535305
#> [11,] 4.450422 4.336832
#> [12,] 4.500000 4.662214
#> [13,] 4.321730 3.784351
#> [14,] 4.303797 4.217557
#> [15,] 4.187764 4.415076
#> [16,] 4.287975 4.390267
#> TCGGGACCAGTATAAG-400.2.2 TCGGGACTCCTTTACA-400.2.2
#> [1,] 4.408350 4.526072
#> [2,] 4.008147 3.980301
#> [3,] 3.938900 4.164542
#> [4,] 4.059063 4.375821
#> [5,] 5.072301 4.842796
#> [6,] 3.955193 4.052530
#> [7,] 4.824847 4.248745
#> [8,] 4.369654 4.462341
#> [9,] 4.006110 4.338355
#> [10,] 4.196538 3.911549
#> [11,] 3.994908 3.925454
#> [12,] 3.692464 4.302047
#> [13,] 4.453157 4.561993
#> [14,] 4.084521 4.173426
#> [15,] 4.131365 4.207416
#> [16,] 4.496945 4.420626
#> TCGGTAAGTAGGACAC-400.2.2 TCGTAGAAGGCTATCT-400.2.2
#> [1,] 4.417129 4.313242
#> [2,] 4.030191 4.014612
#> [3,] 4.052372 4.104110
#> [4,] 4.116451 4.474886
#> [5,] 5.041282 4.821005
#> [6,] 4.254467 3.962557
#> [7,] 4.815773 4.524201
#> [8,] 4.272951 4.594521
#> [9,] 4.256315 4.262100
#> [10,] 4.046211 4.118721
#> [11,] 4.195625 4.026484
#> [12,] 3.970117 4.325114
#> [13,] 4.308071 4.223744
#> [14,] 4.354898 4.317808
#> [15,] 3.732286 4.019178
#> [16,] 4.289587 4.249315
#> TCTATTGGTATGGTTC-400.2.2 TCTCTAAAGCGTTTAC-400.2.2
#> [1,] 4.376096 4.308075
#> [2,] 4.124303 4.337888
#> [3,] 3.980080 3.895652
#> [4,] 4.104382 4.231056
#> [5,] 4.575299 4.535404
#> [6,] 4.422311 4.518012
#> [7,] 4.023108 4.479503
#> [8,] 4.828685 4.842236
#> [9,] 4.400797 4.293168
#> [10,] 4.210359 4.167702
#> [11,] 3.972112 4.228571
#> [12,] 4.108367 4.754037
#> [13,] 4.486056 4.557764
#> [14,] 3.822311 3.997516
#> [15,] 3.866135 4.298137
#> [16,] 4.564940 4.722981
#> TCTCTAAAGTCACGCC-400.2.2 TCTGAGAAGTGAACAT-400.2.2
#> [1,] 4.148231 4.317208
#> [2,] 3.955081 3.700551
#> [3,] 4.271757 3.700245
#> [4,] 4.135317 4.025107
#> [5,] 4.805727 5.705450
#> [6,] 4.112296 4.135640
#> [7,] 4.891072 5.268218
#> [8,] 4.282987 3.966626
#> [9,] 4.315553 4.051745
#> [10,] 3.971926 4.046540
#> [11,] 3.975295 4.095224
#> [12,] 4.115104 4.115432
#> [13,] 4.238630 4.448561
#> [14,] 4.274565 4.507348
#> [15,] 4.123526 3.608696
#> [16,] 4.293094 4.038579
#> TCTGAGAGTAAGAGGA-400.2.2 TCTGGAAGTGTAATGA-400.2.2
#> [1,] 4.440000 4.502114
#> [2,] 4.053846 4.232558
#> [3,] 3.968205 4.069767
#> [4,] 4.108718 4.088795
#> [5,] 4.850769 4.300211
#> [6,] 4.127692 4.428118
#> [7,] 4.741538 4.210359
#> [8,] 4.371795 4.729387
#> [9,] 4.227692 4.660677
#> [10,] 3.919487 4.193446
#> [11,] 4.282564 4.328753
#> [12,] 4.096410 4.631078
#> [13,] 4.156923 4.423890
#> [14,] 4.385128 4.453488
#> [15,] 3.924615 4.053911
#> [16,] 4.459487 4.124736
#> TCTTTCCCATGTCCTC-400.2.2 TGAAAGAAGCAGGTCA-400.2.2
#> [1,] 4.436193 4.641057
#> [2,] 4.350036 3.596804
#> [3,] 4.022711 4.010449
#> [4,] 4.017664 4.365089
#> [5,] 4.688897 4.990781
#> [6,] 3.922495 3.987093
#> [7,] 4.080750 4.411801
#> [8,] 4.770007 4.328826
#> [9,] 4.257751 4.180701
#> [10,] 3.891132 3.992624
#> [11,] 4.538212 4.063921
#> [12,] 4.017304 3.954518
#> [13,] 4.306777 4.081746
#> [14,] 4.609589 4.230486
#> [15,] 3.726388 3.981561
#> [16,] 4.281543 4.178242
#> TGAAAGAAGCCTCGTG-400.2.2 TGACGGCCACAACGTT-400.2.2
#> [1,] 4.689366 4.491620
#> [2,] 4.566231 3.991620
#> [3,] 4.283582 4.277467
#> [4,] 4.208955 4.370577
#> [5,] 4.899254 4.723464
#> [6,] 4.575560 4.472067
#> [7,] 4.484142 4.418994
#> [8,] 4.765858 4.314711
#> [9,] 4.334888 3.990689
#> [10,] 4.277052 4.218808
#> [11,] 4.548507 4.147114
#> [12,] 4.395522 4.352886
#> [13,] 4.114739 4.158287
#> [14,] 3.891791 4.017691
#> [15,] 3.965485 4.230912
#> [16,] 4.313433 4.035382
#> TGACGGCCACTCAGGC-400.2.2 TGACGGCGTCCGAGTC-400.2.2
#> [1,] 4.724392 4.044295
#> [2,] 4.276345 4.183893
#> [3,] 4.076640 3.802685
#> [4,] 3.954311 4.499329
#> [5,] 4.957259 4.908725
#> [6,] 3.741341 4.543624
#> [7,] 4.489315 4.480537
#> [8,] 4.963154 5.387919
#> [9,] 4.165807 5.026846
#> [10,] 3.708180 4.179866
#> [11,] 4.436993 4.598658
#> [12,] 3.857775 4.555705
#> [13,] 3.859985 4.281879
#> [14,] 4.333088 3.930201
#> [15,] 3.837878 3.910067
#> [16,] 4.387620 4.520805
#> TGACTAGGTTTGTGTG-400.2.2 TGACTTTAGTACGCCC-400.2.2
#> [1,] 4.494798 4.362486
#> [2,] 4.542913 3.517837
#> [3,] 4.382315 3.963176
#> [4,] 3.998700 4.413119
#> [5,] 4.723017 5.410817
#> [6,] 4.022107 3.676640
#> [7,] 4.544863 5.276180
#> [8,] 4.915475 4.205984
#> [9,] 4.114434 3.658228
#> [10,] 4.107282 3.795167
#> [11,] 4.374512 4.258918
#> [12,] 4.132640 3.851554
#> [13,] 4.011053 3.857307
#> [14,] 4.578674 4.043728
#> [15,] 4.085176 3.762946
#> [16,] 4.598179 4.036824
#> TGACTTTCAGACAAAT-400.2.2 TGACTTTGTTGCGTTA-400.2.2
#> [1,] 4.478697 4.677449
#> [2,] 4.277360 4.229205
#> [3,] 3.998329 4.116451
#> [4,] 4.246449 3.981516
#> [5,] 4.377611 4.739372
#> [6,] 4.329992 4.714418
#> [7,] 4.328321 4.564695
#> [8,] 4.649958 5.060074
#> [9,] 4.314954 4.524030
#> [10,] 4.309106 4.160813
#> [11,] 4.170426 4.585028
#> [12,] 4.319131 4.621072
#> [13,] 4.415205 4.101664
#> [14,] 4.086884 4.400185
#> [15,] 4.209691 4.050832
#> [16,] 4.244779 4.567468
#> TGAGAGGAGATGCGAC-400.2.2 TGAGAGGAGGGAAACA-400.2.2
#> [1,] 4.837545 4.601300
#> [2,] 4.387485 4.665222
#> [3,] 3.842359 4.328277
#> [4,] 3.932611 4.139762
#> [5,] 4.678700 5.133261
#> [6,] 4.521059 4.850488
#> [7,] 4.385078 4.618635
#> [8,] 5.046931 4.797400
#> [9,] 4.559567 4.463705
#> [10,] 4.375451 4.087757
#> [11,] 4.494585 4.235103
#> [12,] 4.513839 4.355363
#> [13,] 4.398315 4.514626
#> [14,] 4.466907 4.068256
#> [15,] 4.025271 3.992416
#> [16,] 4.548736 4.569881
#> TGAGAGGTCAGATAAG-400.2.2 TGAGCATGTTCCGGCA-400.2.2
#> [1,] 4.716418 4.199615
#> [2,] 5.075775 4.356868
#> [3,] 3.621125 4.406932
#> [4,] 4.436280 4.168806
#> [5,] 4.540758 4.847882
#> [6,] 4.628014 4.704750
#> [7,] 4.447761 4.026958
#> [8,] 4.788749 5.081515
#> [9,] 4.220436 4.801027
#> [10,] 4.805970 4.313222
#> [11,] 4.810563 4.324134
#> [12,] 4.421355 4.327985
#> [13,] 4.485649 4.523107
#> [14,] 4.221584 4.284981
#> [15,] 3.722158 4.116175
#> [16,] 4.320321 4.786906
#> TGAGGGAAGCGTCAAG-400.2.2 TGAGGGAGTCTTGATG-400.2.2
#> [1,] 4.371429 4.625786
#> [2,] 3.938206 3.527044
#> [3,] 4.205316 4.184277
#> [4,] 4.159468 4.069182
#> [5,] 5.079070 4.747799
#> [6,] 4.011960 4.016352
#> [7,] 4.461130 4.770440
#> [8,] 4.364120 4.289937
#> [9,] 3.986047 4.127044
#> [10,] 4.197342 3.817610
#> [11,] 4.388704 4.564780
#> [12,] 4.038538 4.396855
#> [13,] 4.160797 4.182390
#> [14,] 4.297010 4.243396
#> [15,] 4.054485 3.901887
#> [16,] 4.493023 4.079874
#> TGAGGGAGTGGTACAG-400.2.2 TGAGGGATCCCTGACT-400.2.2
#> [1,] 4.605874 4.176703
#> [2,] 3.528005 4.692333
#> [3,] 3.630464 3.923659
#> [4,] 4.262978 4.105956
#> [5,] 5.029372 4.742020
#> [6,] 4.036885 3.710760
#> [7,] 4.698770 4.472195
#> [8,] 4.356557 4.892728
#> [9,] 4.249317 4.393880
#> [10,] 4.100410 4.321158
#> [11,] 3.896175 4.529780
#> [12,] 4.151639 4.281013
#> [13,] 4.353142 4.017111
#> [14,] 4.057377 4.729516
#> [15,] 4.048497 4.100033
#> [16,] 4.127732 4.364265
#> TGATTTCCACATGTGT-400.2.2 TGATTTCGTATCTGCA-400.2.2
#> [1,] 4.228601 4.798648
#> [2,] 4.279749 3.732532
#> [3,] 4.243215 3.840721
#> [4,] 3.747390 3.932382
#> [5,] 4.411273 4.813674
#> [6,] 4.390397 3.983471
#> [7,] 4.028184 5.014275
#> [8,] 4.822547 4.086401
#> [9,] 4.530271 4.397446
#> [10,] 4.433194 4.005259
#> [11,] 4.393528 4.150263
#> [12,] 4.477035 4.114200
#> [13,] 4.407098 4.480090
#> [14,] 4.363257 4.310293
#> [15,] 4.014614 4.118708
#> [16,] 4.510438 4.341848
#> TGCACCTGTAGTAGTA-400.2.2 TGCACCTGTCAACTGT-400.2.2
#> [1,] 4.261796 4.333333
#> [2,] 3.924658 4.466667
#> [3,] 3.902588 4.005031
#> [4,] 4.316591 3.793711
#> [5,] 5.248858 4.357233
#> [6,] 3.969559 4.406289
#> [7,] 4.678843 4.140881
#> [8,] 4.643836 4.789937
#> [9,] 4.194825 4.393711
#> [10,] 4.041096 4.259119
#> [11,] 4.136225 4.138365
#> [12,] 4.066971 4.732075
#> [13,] 4.257991 4.388679
#> [14,] 4.321157 4.114465
#> [15,] 3.850837 4.514465
#> [16,] 4.105023 4.666667
#> TGCACCTGTCCAGTAT-400.2.2 TGCCAAAAGGTTCCTA-400.2.2
#> [1,] 4.3365 4.508299
#> [2,] 3.9150 4.484440
#> [3,] 4.0015 4.154564
#> [4,] 4.4115 4.258299
#> [5,] 4.5200 4.437759
#> [6,] 4.0855 4.254149
#> [7,] 4.7600 4.348548
#> [8,] 4.3700 4.701245
#> [9,] 4.3420 4.576763
#> [10,] 3.8360 4.080913
#> [11,] 4.1385 4.295643
#> [12,] 4.0305 4.268672
#> [13,] 4.3280 4.614108
#> [14,] 4.1195 4.316390
#> [15,] 3.8740 4.332988
#> [16,] 4.2310 4.618257
#> TGCCCATAGGAGTCTG-400.2.2 TGCCCTAAGCTAGTGG-400.2.2
#> [1,] 4.598214 4.387209
#> [2,] 4.405032 4.475581
#> [3,] 4.259740 4.425581
#> [4,] 4.053571 4.304651
#> [5,] 4.384740 4.494186
#> [6,] 4.264610 4.358140
#> [7,] 4.245130 4.261628
#> [8,] 4.399351 4.573256
#> [9,] 4.989448 4.563953
#> [10,] 4.331169 4.427907
#> [11,] 4.135552 4.513953
#> [12,] 4.659903 4.609302
#> [13,] 4.700487 4.359302
#> [14,] 4.248377 4.344186
#> [15,] 4.129870 4.287209
#> [16,] 4.574675 4.675581
#> TGCGCAGTCAATAAGG-400.2.2 TGCGGGTAGTCAAGCG-400.2.2
#> [1,] 4.928691 4.308834
#> [2,] 3.914430 4.158872
#> [3,] 3.903523 4.201188
#> [4,] 3.958893 4.033408
#> [5,] 5.051174 4.909428
#> [6,] 4.026846 3.870082
#> [7,] 4.626678 4.112101
#> [8,] 4.264262 4.797327
#> [9,] 4.056208 4.327394
#> [10,] 3.520134 4.061618
#> [11,] 4.572987 4.452116
#> [12,] 4.331376 4.088344
#> [13,] 4.426174 4.096511
#> [14,] 4.088087 4.284336
#> [15,] 3.739933 4.111359
#> [16,] 4.508389 4.645880
#> TGCGTGGGTGGCCCTA-400.2.2 TGCGTGGTCCACGTTC-400.2.2
#> [1,] 4.373860 4.434343
#> [2,] 4.161854 3.770202
#> [3,] 4.494681 4.183502
#> [4,] 4.242401 4.101010
#> [5,] 4.391337 5.179293
#> [6,] 4.316869 3.770202
#> [7,] 4.280395 4.942761
#> [8,] 4.836626 4.288721
#> [9,] 4.676292 3.874579
#> [10,] 4.231003 3.829125
#> [11,] 4.373100 3.742424
#> [12,] 4.277356 3.907407
#> [13,] 4.430091 4.270202
#> [14,] 4.208967 4.133838
#> [15,] 4.329027 3.989057
#> [16,] 4.350304 4.356902
#> TGCTACCAGGAGCGTT-400.2.2 TGCTACCTCCTCAACC-400.2.2
#> [1,] 4.477817 4.550588
#> [2,] 4.422360 4.087059
#> [3,] 4.461846 4.125882
#> [4,] 4.076752 3.862941
#> [5,] 4.687666 4.731176
#> [6,] 4.178793 4.044118
#> [7,] 4.797693 4.211176
#> [8,] 4.212067 4.549412
#> [9,] 4.446318 4.048235
#> [10,] 4.290151 3.950588
#> [11,] 4.304791 4.097059
#> [12,] 4.269743 4.061765
#> [13,] 4.447649 4.248235
#> [14,] 4.450311 4.145882
#> [15,] 4.403727 4.172941
#> [16,] 4.328749 4.685882
#> TGGACGCGTCTTGATG-400.2.2 TGGACGCTCTCTAAGG-400.2.2
#> [1,] 4.150188 4.049913
#> [2,] 5.028786 4.133488
#> [3,] 3.613267 3.984330
#> [4,] 4.357947 4.058038
#> [5,] 4.520651 5.197911
#> [6,] 4.396746 3.951828
#> [7,] 3.675845 5.149739
#> [8,] 4.799750 4.420197
#> [9,] 4.107635 3.930354
#> [10,] 5.255319 4.195009
#> [11,] 3.896120 4.269298
#> [12,] 4.518148 4.051654
#> [13,] 4.847309 4.028439
#> [14,] 4.023780 4.523506
#> [15,] 4.707134 3.990133
#> [16,] 4.146433 4.213001
#> TGGACGCTCTTTACGT-400.2.2 TGGCCAGGTATAAACG-400.2.2
#> [1,] 4.250867 4.468395
#> [2,] 4.284393 3.741086
#> [3,] 4.209249 3.839951
#> [4,] 4.025434 4.087115
#> [5,] 4.995376 5.163695
#> [6,] 4.287861 3.826985
#> [7,] 3.937572 4.994327
#> [8,] 4.573410 4.104133
#> [9,] 4.573410 3.993112
#> [10,] 4.457803 3.671394
#> [11,] 4.442775 4.188006
#> [12,] 4.508671 4.152350
#> [13,] 4.376879 4.346029
#> [14,] 4.401156 4.332658
#> [15,] 4.206936 3.581037
#> [16,] 4.648555 3.898298
#> TGGCTGGCACGTCTCT-400.2.2 TGGCTGGTCACTTATC-400.2.2
#> [1,] 4.850558 4.565141
#> [2,] 3.513755 4.227113
#> [3,] 3.860967 4.343310
#> [4,] 4.353160 4.335387
#> [5,] 5.217844 5.115317
#> [6,] 3.897398 3.775528
#> [7,] 4.873606 4.058979
#> [8,] 4.373978 4.887324
#> [9,] 4.175465 4.073063
#> [10,] 3.637175 3.668134
#> [11,] 4.214870 4.426937
#> [12,] 3.896654 4.104754
#> [13,] 4.106320 4.122359
#> [14,] 4.455019 4.197183
#> [15,] 3.768773 4.106514
#> [16,] 4.272862 4.569542
#> TGGGCGTGTCTGATCA-400.2.2 TGGTTAGGTGTTCGAT-400.2.2
#> [1,] 4.444523 4.230327
#> [2,] 3.643110 4.058587
#> [3,] 3.973852 4.126364
#> [4,] 4.228269 4.361861
#> [5,] 4.907420 4.863871
#> [6,] 3.668551 4.129810
#> [7,] 4.527208 4.458932
#> [8,] 4.421908 4.790350
#> [9,] 3.922968 4.157381
#> [10,] 3.835336 4.088455
#> [11,] 3.598587 4.002298
#> [12,] 4.235336 4.179782
#> [13,] 4.229682 4.273980
#> [14,] 4.106007 3.897186
#> [15,] 4.312367 4.148765
#> [16,] 3.898233 4.279724
#> TGGTTCCTCATCGATG-400.2.2 TGGTTCCTCTCCGGTT-400.2.2
#> [1,] 4.607143 4.547059
#> [2,] 4.424107 4.175490
#> [3,] 4.087054 4.187255
#> [4,] 4.187500 4.539216
#> [5,] 4.620536 4.198039
#> [6,] 4.381696 4.502941
#> [7,] 4.580357 4.221569
#> [8,] 4.646205 4.804902
#> [9,] 4.521205 4.725490
#> [10,] 4.222098 4.742157
#> [11,] 4.419643 4.403922
#> [12,] 4.603795 4.607843
#> [13,] 4.099330 4.617647
#> [14,] 4.145089 4.407843
#> [15,] 4.330357 4.426471
#> [16,] 4.890625 4.453922
#> TGTATTCAGTTACCCA-400.2.2 TGTATTCGTACACCGC-400.2.2
#> [1,] 4.596491 4.399612
#> [2,] 4.144737 4.014549
#> [3,] 4.271930 4.104753
#> [4,] 4.182018 4.074685
#> [5,] 4.507675 4.419011
#> [6,] 4.000000 4.674103
#> [7,] 4.310307 4.270611
#> [8,] 4.436404 5.090204
#> [9,] 4.686404 4.836081
#> [10,] 3.808114 4.212415
#> [11,] 4.172149 4.452958
#> [12,] 4.605263 4.665373
#> [13,] 4.809211 4.263822
#> [14,] 4.331140 4.314258
#> [15,] 3.844298 4.040737
#> [16,] 4.307018 4.603298
#> TGTGGTAAGCTAACAA-400.2.2 TGTGGTAGTCTAGCCG-400.2.2
#> [1,] 4.540692 4.633898
#> [2,] 4.299345 4.104237
#> [3,] 4.414406 4.372034
#> [4,] 4.483630 4.416102
#> [5,] 4.246960 4.530508
#> [6,] 4.593078 4.308475
#> [7,] 4.181478 4.031356
#> [8,] 4.826941 4.780508
#> [9,] 4.602432 4.568644
#> [10,] 4.388213 4.172881
#> [11,] 4.423761 4.163559
#> [12,] 4.596819 4.400847
#> [13,] 4.404116 4.363559
#> [14,] 4.308700 4.120339
#> [15,] 4.435921 3.993220
#> [16,] 4.148737 4.622034
#> TGTGTTTCACCATCCT-400.2.2 TGTGTTTCATTGGTAC-400.2.2
#> [1,] 4.095140 4.222646
#> [2,] 4.467425 3.913486
#> [3,] 4.172699 4.087150
#> [4,] 4.338159 4.282443
#> [5,] 4.300931 4.930662
#> [6,] 4.294726 3.894402
#> [7,] 4.409514 4.770356
#> [8,] 4.914168 4.413486
#> [9,] 4.736298 4.353053
#> [10,] 4.568769 4.033079
#> [11,] 4.388831 4.112595
#> [12,] 4.099276 4.019084
#> [13,] 4.216132 4.164122
#> [14,] 4.080662 4.424936
#> [15,] 4.559462 3.833333
#> [16,] 4.661841 4.002545
#> TGTGTTTGTGTTGAGG-400.2.2 TGTTCCGTCACCGTAA-400.2.2
#> [1,] 4.115776 4.177022
#> [2,] 4.226463 4.280188
#> [3,] 3.952926 4.230950
#> [4,] 4.034351 4.334115
#> [5,] 4.026718 4.940211
#> [6,] 4.120865 4.297773
#> [7,] 4.370229 4.044549
#> [8,] 4.711196 4.580305
#> [9,] 4.491094 4.589683
#> [10,] 4.269720 4.287222
#> [11,] 4.175573 4.164127
#> [12,] 4.480916 4.396249
#> [13,] 4.591603 4.079719
#> [14,] 4.055980 3.964830
#> [15,] 4.118321 4.194607
#> [16,] 4.745547 4.379836
#> TGTTCCGTCATTGCGA-400.2.2 TTAACTCAGATCGATA-400.2.2
#> [1,] 4.172963 4.477273
#> [2,] 4.193625 4.344545
#> [3,] 4.143447 4.352727
#> [4,] 3.847698 4.500000
#> [5,] 4.801063 4.320000
#> [6,] 4.282172 4.571818
#> [7,] 4.761511 4.715455
#> [8,] 4.468713 4.903636
#> [9,] 4.262102 4.325455
#> [10,] 3.994097 4.741818
#> [11,] 4.296930 4.313636
#> [12,] 4.510626 4.436364
#> [13,] 4.144628 4.364545
#> [14,] 4.335301 4.129091
#> [15,] 4.213695 4.252727
#> [16,] 4.475797 4.215455
#> TTAACTCGTCGCATAT-400.2.2 TTAACTCTCTCTTATG-400.2.2
#> [1,] 4.304311 4.647987
#> [2,] 3.789518 3.624309
#> [3,] 4.090448 3.773481
#> [4,] 4.033812 4.001579
#> [5,] 5.327980 5.443567
#> [6,] 3.832629 3.984215
#> [7,] 4.911243 4.959747
#> [8,] 4.227388 4.164957
#> [9,] 4.322063 3.839779
#> [10,] 4.086221 3.973165
#> [11,] 3.934066 4.280979
#> [12,] 4.054945 4.086030
#> [13,] 4.307692 4.336227
#> [14,] 4.313609 4.250987
#> [15,] 3.886729 4.047356
#> [16,] 4.219780 4.531176
#> TTAGGCAAGGATATAC-400.2.2 TTATGCTAGAGACTTA-400.2.2
#> [1,] 4.495575 4.301364
#> [2,] 3.415929 3.749197
#> [3,] 3.575221 3.859551
#> [4,] 4.639381 4.192215
#> [5,] 4.918142 5.375201
#> [6,] 3.644912 4.221910
#> [7,] 5.257743 5.085474
#> [8,] 4.170354 4.327448
#> [9,] 3.866150 3.936196
#> [10,] 3.745575 3.968700
#> [11,] 3.932522 4.344302
#> [12,] 3.620575 4.223515
#> [13,] 4.085177 4.071429
#> [14,] 4.433628 4.197833
#> [15,] 3.651549 3.691814
#> [16,] 3.923673 4.208668
#> TTCGAAGAGCTGCCCA-400.2.2 TTCGAAGCAAAGCAAT-400.2.2
#> [1,] 4.635026 4.333943
#> [2,] 3.765269 4.405306
#> [3,] 3.814570 4.316560
#> [4,] 4.312730 4.228728
#> [5,] 5.237675 4.430009
#> [6,] 4.033848 4.193047
#> [7,] 5.169978 4.085087
#> [8,] 4.277410 5.000915
#> [9,] 4.275938 4.577310
#> [10,] 3.930096 4.155535
#> [11,] 4.210449 4.267155
#> [12,] 4.101545 4.302836
#> [13,] 4.225901 4.401647
#> [14,] 4.506255 4.242452
#> [15,] 3.698308 4.110704
#> [16,] 3.816777 4.561757
#> TTCGAAGTCGAATCCA-400.2.2 TTCGGTCAGGTAGCCA-400.2.2
#> [1,] 4.203895 4.490869
#> [2,] 4.022520 4.572681
#> [3,] 3.914790 4.168736
#> [4,] 4.202069 4.144631
#> [5,] 5.119903 4.568298
#> [6,] 4.032867 4.466764
#> [7,] 4.940353 4.199416
#> [8,] 4.388923 4.944485
#> [9,] 4.308582 4.969321
#> [10,] 4.220329 4.215486
#> [11,] 4.008521 4.134405
#> [12,] 4.499087 4.688093
#> [13,] 4.541083 4.468225
#> [14,] 4.097991 4.360847
#> [15,] 4.129032 4.019722
#> [16,] 4.172246 4.950329
#> TTCGGTCGTTGCGCAC-400.2.2 TTCTACAAGCCTATGT-400.2.2
#> [1,] 4.388761 4.187266
#> [2,] 4.307339 4.325218
#> [3,] 4.292431 4.368290
#> [4,] 4.188073 4.136704
#> [5,] 4.596330 4.524969
#> [6,] 4.684633 4.180400
#> [7,] 4.049312 4.439451
#> [8,] 4.973624 4.553683
#> [9,] 4.386468 4.444444
#> [10,] 4.153670 3.971286
#> [11,] 4.420872 4.199750
#> [12,] 4.102064 4.605493
#> [13,] 4.669725 4.494382
#> [14,] 4.370413 4.419476
#> [15,] 4.405963 4.390762
#> [16,] 4.940367 4.290886
#> TTCTACAGTGCAACTT-400.2.2 TTCTCAACACGAAGCA-400.2.2
#> [1,] 4.429630 4.368655
#> [2,] 3.801646 4.052242
#> [3,] 3.897942 4.137999
#> [4,] 4.182716 3.970922
#> [5,] 5.111111 4.495811
#> [6,] 4.085597 4.100049
#> [7,] 4.952263 4.105471
#> [8,] 4.178601 4.884672
#> [9,] 4.066667 4.440118
#> [10,] 4.086420 4.395269
#> [11,] 4.394239 4.105964
#> [12,] 4.193416 4.465254
#> [13,] 4.157202 4.671267
#> [14,] 4.452675 3.941350
#> [15,] 3.792593 4.153770
#> [16,] 4.234568 4.603746
#> TTCTCCTCAAGAGGCT-400.2.2 TTCTCCTTCGCAGGCT-400.2.2
#> [1,] 4.633621 4.934848
#> [2,] 3.992816 3.545129
#> [3,] 3.875718 3.716677
#> [4,] 3.949713 4.115362
#> [5,] 4.684626 5.448296
#> [6,] 3.918822 3.857741
#> [7,] 4.658046 4.582188
#> [8,] 4.346983 4.319187
#> [9,] 4.199713 4.086671
#> [10,] 3.709770 3.450090
#> [11,] 4.068247 3.806934
#> [12,] 3.878592 3.769874
#> [13,] 4.222701 3.975493
#> [14,] 4.130747 4.307233
#> [15,] 3.939655 4.019127
#> [16,] 4.441810 4.608488
#> TTGCGTCGTACGACCC-400.2.2 TTGGAACAGTACGACG-400.2.2
#> [1,] 4.322539 4.287783
#> [2,] 4.005181 4.535747
#> [3,] 3.870466 4.782805
#> [4,] 4.046632 4.362896
#> [5,] 4.067358 4.425339
#> [6,] 4.740933 4.184615
#> [7,] 4.540155 4.443439
#> [8,] 4.531088 4.609050
#> [9,] 4.765544 4.457014
#> [10,] 3.922280 4.304977
#> [11,] 4.404145 4.330317
#> [12,] 4.531088 4.409955
#> [13,] 4.500000 4.115837
#> [14,] 4.205959 4.198190
#> [15,] 4.261658 4.289593
#> [16,] 4.791451 4.155656
#> TTGGAACGTACATGTC-400.2.2 TTGTAGGAGCCACTAT-400.2.2
#> [1,] 4.354109 4.328039
#> [2,] 4.034197 4.041539
#> [3,] 4.291230 4.382407
#> [4,] 4.453944 4.157605
#> [5,] 4.617761 5.003665
#> [6,] 3.923883 5.020770
#> [7,] 4.636514 4.560782
#> [8,] 4.339768 4.897373
#> [9,] 4.138996 4.749542
#> [10,] 4.097077 4.365913
#> [11,] 4.085494 4.819792
#> [12,] 4.237728 4.267563
#> [13,] 4.047987 3.890043
#> [14,] 4.308880 4.372022
#> [15,] 3.914506 4.193647
#> [16,] 4.204633 4.491142
#> TTGTAGGCACATTTCT-400.2.2 TTGTAGGGTTGCTCCT-400.2.2
#> [1,] 4.318267 4.301333
#> [2,] 4.209040 4.250667
#> [3,] 4.129944 4.137333
#> [4,] 4.154426 4.149333
#> [5,] 4.718142 4.377333
#> [6,] 4.077841 4.650667
#> [7,] 4.173258 4.270667
#> [8,] 4.668550 4.796000
#> [9,] 4.270559 4.557333
#> [10,] 4.194601 4.108000
#> [11,] 4.175769 4.469333
#> [12,] 4.556183 4.385333
#> [13,] 4.181419 4.261333
#> [14,] 4.111739 4.322667
#> [15,] 4.509730 3.856000
#> [16,] 4.377276 4.604000
#> TTGTAGGTCCACGAAT-400.2.2 TTTACTGAGTAGGTGC-400.2.2
#> [1,] 4.180887 4.478435
#> [2,] 3.850512 4.087262
#> [3,] 4.035495 4.335005
#> [4,] 4.167235 3.852558
#> [5,] 4.535836 4.810431
#> [6,] 4.049829 3.950853
#> [7,] 4.717406 4.291876
#> [8,] 4.301024 4.401204
#> [9,] 4.198635 4.299900
#> [10,] 4.054608 3.889669
#> [11,] 3.972014 4.056169
#> [12,] 3.908532 4.745236
#> [13,] 4.445734 4.555667
#> [14,] 3.917406 4.063190
#> [15,] 3.978840 4.336008
#> [16,] 4.085324 4.840522
#> TTTATGCAGAAGGGTA-400.2.2 TTTATGCGTAAACGCG-400.2.2
#> [1,] 4.268571 4.210294
#> [2,] 4.083636 4.302941
#> [3,] 4.252987 4.396324
#> [4,] 4.174545 4.085294
#> [5,] 4.690390 4.729412
#> [6,] 4.716364 4.264706
#> [7,] 4.357403 4.005147
#> [8,] 4.810909 4.918382
#> [9,] 4.681039 4.456618
#> [10,] 4.126753 4.364706
#> [11,] 4.565714 4.253676
#> [12,] 4.515325 4.163971
#> [13,] 4.184416 4.389706
#> [14,] 4.001558 4.368382
#> [15,] 4.170909 3.997059
#> [16,] 4.397403 4.191912
#> TTTATGCTCGCGCCAA-400.2.2 TTTCCTCCAATAGAGT-400.2.2
#> [1,] 4.240126 4.051680
#> [2,] 4.695103 4.276486
#> [3,] 4.253555 3.832041
#> [4,] 3.761453 4.333333
#> [5,] 4.598736 4.360465
#> [6,] 4.259874 4.149871
#> [7,] 4.147709 4.369509
#> [8,] 4.830964 4.909561
#> [9,] 4.879147 4.366925
#> [10,] 4.205371 4.590439
#> [11,] 4.295419 4.507752
#> [12,] 4.377567 4.355297
#> [13,] 4.192733 4.638243
#> [14,] 4.461295 4.259690
#> [15,] 4.357820 4.379845
#> [16,] 4.515798 4.621447
#> TTTGCGCAGAGCCCAA-400.2.2 TTTGCGCCAGTAGAGC-400.2.2
#> [1,] 4.290039 4.808219
#> [2,] 4.348633 4.969863
#> [3,] 4.132812 3.657534
#> [4,] 3.916016 4.162557
#> [5,] 4.517578 4.664840
#> [6,] 4.338867 4.649315
#> [7,] 4.348633 4.216438
#> [8,] 4.585938 4.698630
#> [9,] 4.462891 4.024658
#> [10,] 4.667969 5.282192
#> [11,] 4.491211 4.388128
#> [12,] 4.489258 4.243836
#> [13,] 4.184570 4.547032
#> [14,] 3.995117 4.294977
#> [15,] 3.792969 3.989954
#> [16,] 4.087891 4.464840
#> TTTGGTTAGTCCCACG-400.2.2 TTTGGTTCACGACGAA-400.2.2
#> [1,] 4.190692 4.327648
#> [2,] 4.331442 4.297127
#> [3,] 4.254257 4.156194
#> [4,] 4.118048 3.906643
#> [5,] 4.442679 4.555655
#> [6,] 4.396141 4.169659
#> [7,] 4.366629 4.397666
#> [8,] 4.486947 4.499102
#> [9,] 4.233825 4.258528
#> [10,] 4.317821 4.236984
#> [11,] 4.331442 3.851885
#> [12,] 4.334847 4.487433
#> [13,] 4.032917 3.910233
#> [14,] 3.972758 4.288151
#> [15,] 4.054484 4.128366
#> [16,] 4.185017 4.368043
#> TTTGTCATCCAGTAGT-400.2.2 AAACCTGAGACAATAC-400.2.3
#> [1,] 4.387397 4.607296
#> [2,] 4.335744 3.918455
#> [3,] 4.263430 3.949571
#> [4,] 4.393595 4.314378
#> [5,] 4.460744 5.127682
#> [6,] 4.265496 3.949571
#> [7,] 4.127066 4.608369
#> [8,] 5.117769 4.335837
#> [9,] 5.016529 4.076180
#> [10,] 4.290289 4.100858
#> [11,] 4.413223 3.675966
#> [12,] 4.413223 4.194206
#> [13,] 4.383264 4.622318
#> [14,] 4.474174 4.055794
#> [15,] 3.985537 3.814378
#> [16,] 4.724174 4.006438
#> AAACCTGCAGATAATG-400.2.3 AAACCTGTCCCGACTT-400.2.3
#> [1,] 4.004990 4.217463
#> [2,] 3.888224 3.907194
#> [3,] 3.882236 4.209226
#> [4,] 3.992016 4.137836
#> [5,] 5.205589 4.593630
#> [6,] 3.846307 4.065898
#> [7,] 5.061876 4.668863
#> [8,] 4.333333 4.151565
#> [9,] 4.476048 4.256452
#> [10,] 3.759481 3.887424
#> [11,] 4.129741 3.969248
#> [12,] 4.168663 4.388797
#> [13,] 4.436128 4.123009
#> [14,] 4.494012 4.354750
#> [15,] 3.720559 4.418451
#> [16,] 4.448104 4.531027
#> AAACGGGAGCTGAAAT-400.2.3 AAACGGGCATGGGACA-400.2.3
#> [1,] 4.709710 4.349673
#> [2,] 3.982983 4.163399
#> [3,] 3.661662 4.140523
#> [4,] 3.916917 4.086057
#> [5,] 5.144144 5.180283
#> [6,] 3.951952 4.130719
#> [7,] 4.614615 4.856209
#> [8,] 4.651652 4.488017
#> [9,] 4.061061 4.116558
#> [10,] 3.685686 4.102941
#> [11,] 4.495495 4.309913
#> [12,] 3.938939 3.902505
#> [13,] 4.151151 4.183007
#> [14,] 4.468468 4.368192
#> [15,] 3.905906 3.671569
#> [16,] 4.423423 4.255991
#> AAAGATGAGCGATCCC-400.2.3 AAAGATGGTAATCACC-400.2.3
#> [1,] 4.367435 4.433962
#> [2,] 4.213977 3.817610
#> [3,] 4.180836 3.997410
#> [4,] 4.046110 4.019238
#> [5,] 4.856628 5.272290
#> [6,] 4.003602 4.116167
#> [7,] 4.350144 4.857936
#> [8,] 4.534582 4.236404
#> [9,] 4.384726 4.214576
#> [10,] 4.047550 3.927858
#> [11,] 4.103026 4.107288
#> [12,] 4.371758 4.118387
#> [13,] 4.635447 4.084721
#> [14,] 4.064841 4.492786
#> [15,] 4.068444 3.759156
#> [16,] 4.550432 4.249353
#> AAAGCAAAGAGACTAT-400.2.3 AAAGCAAGTAGCAAAT-400.2.3
#> [1,] 4.577614 4.194559
#> [2,] 4.342133 4.374279
#> [3,] 4.030623 4.248969
#> [4,] 4.011616 4.131904
#> [5,] 4.807814 4.647980
#> [6,] 4.633580 4.150866
#> [7,] 4.394931 4.395713
#> [8,] 4.874340 4.465787
#> [9,] 4.586061 4.539984
#> [10,] 3.954593 4.149217
#> [11,] 4.361140 4.241550
#> [12,] 4.406547 4.703215
#> [13,] 4.353749 4.429514
#> [14,] 4.255544 3.971146
#> [15,] 3.875396 4.039571
#> [16,] 4.524815 4.634790
#> AAAGCAATCCGCAAGC-400.2.3 AAAGTAGCAGTAAGAT-400.2.3
#> [1,] 4.406852 4.100103
#> [2,] 4.190578 4.345717
#> [3,] 4.141328 3.897833
#> [4,] 4.104925 4.203302
#> [5,] 4.611884 4.246646
#> [6,] 4.409529 4.719298
#> [7,] 4.345289 4.591331
#> [8,] 4.577623 4.712074
#> [9,] 4.512313 4.950464
#> [10,] 4.271413 4.449948
#> [11,] 4.482869 4.370485
#> [12,] 4.412741 4.404541
#> [13,] 4.335118 4.665635
#> [14,] 4.066381 4.170279
#> [15,] 4.201820 3.911249
#> [16,] 4.411135 4.735810
#> AAAGTAGGTGTCGCTG-400.2.3 AACACGTAGAGGTACC-400.2.3
#> [1,] 4.295517 4.407035
#> [2,] 4.106130 4.110553
#> [3,] 4.139982 4.402010
#> [4,] 4.076853 4.128141
#> [5,] 4.388838 4.991206
#> [6,] 4.048490 4.726131
#> [7,] 4.248856 4.368090
#> [8,] 4.620311 4.733668
#> [9,] 4.682525 4.425879
#> [10,] 3.710887 4.262563
#> [11,] 4.347667 4.169598
#> [12,] 4.529735 4.575377
#> [13,] 4.675206 4.395729
#> [14,] 4.258920 3.816583
#> [15,] 4.416285 4.145729
#> [16,] 4.414456 4.687186
#> AACACGTGTTCTCATT-400.2.3 AACCGCGTCGGCTACG-400.2.3
#> [1,] 4.212746 4.492454
#> [2,] 4.505155 4.239873
#> [3,] 4.328022 4.250199
#> [4,] 4.382381 4.303415
#> [5,] 4.313027 4.579825
#> [6,] 4.506092 4.316124
#> [7,] 4.012184 4.370135
#> [8,] 4.985005 4.841938
#> [9,] 4.875351 4.518666
#> [10,] 4.667291 4.552025
#> [11,] 4.360825 4.416998
#> [12,] 4.118088 4.334392
#> [13,] 4.270853 4.274821
#> [14,] 4.516401 4.190627
#> [15,] 4.564199 4.154091
#> [16,] 4.211809 4.469420
#> AACCGCGTCTATCCCG-400.2.3 AACGTTGCATCCCATC-400.2.3
#> [1,] 4.595852 4.281883
#> [2,] 3.542040 4.054187
#> [3,] 3.970852 3.902025
#> [4,] 4.302130 4.090859
#> [5,] 5.251682 4.979201
#> [6,] 3.673206 4.061303
#> [7,] 4.979821 4.441708
#> [8,] 4.163677 4.540777
#> [9,] 4.204036 4.127531
#> [10,] 3.600897 3.945265
#> [11,] 4.070628 3.985769
#> [12,] 4.099215 4.324028
#> [13,] 4.019058 4.293924
#> [14,] 4.141816 4.261631
#> [15,] 4.228139 4.044335
#> [16,] 4.233744 4.133005
#> AACTCAGAGTCTCAAC-400.2.3 AACTCAGCACATCCGG-400.2.3
#> [1,] 4.490081 4.580147
#> [2,] 3.778839 3.736029
#> [3,] 4.186627 4.188235
#> [4,] 4.027921 4.130147
#> [5,] 5.008817 4.624265
#> [6,] 3.817046 3.676471
#> [7,] 4.616458 4.479412
#> [8,] 4.541514 4.425000
#> [9,] 4.178545 4.581618
#> [10,] 4.019838 3.805147
#> [11,] 4.321822 3.875735
#> [12,] 3.883909 4.283088
#> [13,] 3.982366 4.462500
#> [14,] 4.135929 4.442647
#> [15,] 4.204996 3.941176
#> [16,] 4.759735 4.189706
#> AACTCAGGTGTTGGGA-400.2.3 AACTCAGTCGTCTGCT-400.2.3
#> [1,] 4.711875 4.414376
#> [2,] 4.612500 3.970825
#> [3,] 4.458750 4.129387
#> [4,] 4.321875 3.976321
#> [5,] 4.470000 4.513319
#> [6,] 4.459375 4.277801
#> [7,] 4.316875 4.721776
#> [8,] 4.448125 4.361099
#> [9,] 4.155625 4.515433
#> [10,] 4.567500 3.808457
#> [11,] 4.360000 4.722199
#> [12,] 4.411250 4.193658
#> [13,] 4.332500 4.176744
#> [14,] 4.115625 3.930655
#> [15,] 4.028750 4.210994
#> [16,] 4.388750 4.079915
#> AACTCCCCATATACCG-400.2.3 AACTCTTCAGAGTGTG-400.2.3
#> [1,] 4.455752 4.150571
#> [2,] 3.661504 4.618899
#> [3,] 4.262537 4.183801
#> [4,] 3.892330 3.872274
#> [5,] 4.885693 4.247144
#> [6,] 4.009587 4.193146
#> [7,] 5.054572 4.085151
#> [8,] 4.409292 5.055036
#> [9,] 4.278761 4.233645
#> [10,] 4.294985 4.247144
#> [11,] 4.324484 4.714434
#> [12,] 4.132006 4.234683
#> [13,] 4.221239 4.188993
#> [14,] 4.183628 4.526480
#> [15,] 3.789086 3.719626
#> [16,] 4.175516 4.555556
#> AACTCTTGTAAATACG-400.2.3 AACTTTCCAGATAATG-400.2.3
#> [1,] 4.468489 4.419162
#> [2,] 3.847183 3.845167
#> [3,] 3.774122 4.239521
#> [4,] 4.362521 4.408896
#> [5,] 4.628555 4.798118
#> [6,] 4.264361 4.056459
#> [7,] 4.790853 4.721985
#> [8,] 4.344116 4.475620
#> [9,] 4.068600 3.786142
#> [10,] 4.023424 3.999145
#> [11,] 4.009481 3.729683
#> [12,] 4.069158 3.839179
#> [13,] 4.204685 4.236955
#> [14,] 4.174568 4.020530
#> [15,] 3.713887 4.079555
#> [16,] 4.087563 4.318221
#> AACTTTCTCTGTCTCG-400.2.3 AAGACCTCATGTAAGA-400.2.3
#> [1,] 4.401309 4.403785
#> [2,] 4.491821 4.385910
#> [3,] 4.047983 4.180862
#> [4,] 4.343511 4.373291
#> [5,] 4.584515 4.661409
#> [6,] 4.714286 3.908517
#> [7,] 4.448201 4.222923
#> [8,] 5.011996 4.770768
#> [9,] 4.303162 4.078864
#> [10,] 4.310796 4.229232
#> [11,] 4.824427 4.336488
#> [12,] 4.575791 4.334385
#> [13,] 4.153762 4.644585
#> [14,] 4.118866 3.732913
#> [15,] 3.941112 4.187171
#> [16,] 4.538713 4.426919
#> AAGCCGCAGCGCCTCA-400.2.3 AAGCCGCGTCTCTTAT-400.2.3
#> [1,] 4.308280 4.494118
#> [2,] 4.284076 3.956471
#> [3,] 4.500637 4.223529
#> [4,] 4.175796 4.071765
#> [5,] 4.366879 4.561176
#> [6,] 4.113376 4.616471
#> [7,] 4.240764 4.498824
#> [8,] 4.838217 4.996471
#> [9,] 4.814013 4.638824
#> [10,] 4.351592 4.260000
#> [11,] 4.596178 4.410588
#> [12,] 4.601274 4.628235
#> [13,] 4.591083 4.660000
#> [14,] 4.351592 4.177647
#> [15,] 4.332484 4.147059
#> [16,] 4.582166 4.607059
#> AAGCCGCGTTCAGCGC-400.2.3 AAGGAGCAGCCCGAAA-400.2.3
#> [1,] 4.486040 4.240949
#> [2,] 3.777778 4.455680
#> [3,] 3.894017 4.263421
#> [4,] 4.403419 4.329588
#> [5,] 4.941880 4.905119
#> [6,] 3.820513 4.397004
#> [7,] 4.569231 4.630462
#> [8,] 4.506553 4.907615
#> [9,] 4.182906 4.569288
#> [10,] 3.882621 4.031211
#> [11,] 3.974929 4.304619
#> [12,] 4.075214 4.343321
#> [13,] 4.337322 4.234707
#> [14,] 4.217664 4.249688
#> [15,] 3.814245 3.920100
#> [16,] 4.015385 4.836454
#> AAGGAGCCATCACCCT-400.2.3 AAGGAGCGTTCTGGTA-400.2.3
#> [1,] 4.347886 4.211349
#> [2,] 3.909910 3.833882
#> [3,] 4.111573 4.214638
#> [4,] 4.226611 4.177632
#> [5,] 4.772696 4.652138
#> [6,] 3.995149 3.866776
#> [7,] 4.877339 4.870066
#> [8,] 4.506584 4.398849
#> [9,] 4.060291 4.203947
#> [10,] 3.965350 3.786184
#> [11,] 3.976438 4.111842
#> [12,] 4.013860 4.237664
#> [13,] 4.300762 3.847862
#> [14,] 4.049203 4.243421
#> [15,] 3.776854 4.221217
#> [16,] 4.290367 4.501645
#> AAGGAGCGTTGCGTTA-400.2.3 AAGGAGCGTTTGACAC-400.2.3
#> [1,] 4.511422 4.138561
#> [2,] 4.236551 3.978733
#> [3,] 4.016949 4.173577
#> [4,] 3.967576 4.152954
#> [5,] 4.781872 5.306767
#> [6,] 4.384672 4.295596
#> [7,] 4.271186 5.017186
#> [8,] 4.694178 4.346294
#> [9,] 4.358143 4.288722
#> [10,] 4.061901 4.164769
#> [11,] 4.306559 4.232009
#> [12,] 3.997052 4.043179
#> [13,] 4.451732 4.189689
#> [14,] 4.109064 4.511708
#> [15,] 4.130435 3.915789
#> [16,] 4.688283 4.321160
#> AAGGCAGGTCCGCTGA-400.2.3 AAGGCAGTCAGCATGT-400.2.3
#> [1,] 4.380650 4.527346
#> [2,] 4.017446 4.182309
#> [3,] 4.353688 4.177583
#> [4,] 4.053132 4.043214
#> [5,] 4.946868 4.526671
#> [6,] 4.072165 4.267387
#> [7,] 4.086439 4.141121
#> [8,] 5.052339 4.835922
#> [9,] 4.419508 4.746793
#> [10,] 3.842189 4.293720
#> [11,] 4.241079 4.099932
#> [12,] 3.745440 4.333558
#> [13,] 4.465504 4.540851
#> [14,] 4.309278 4.120189
#> [15,] 3.942109 4.272789
#> [16,] 4.451229 4.511141
#> AAGGTTCCAGTTTACG-400.2.3 AAGGTTCTCAGTTCGA-400.2.3
#> [1,] 4.171301 4.267320
#> [2,] 4.498331 3.837393
#> [3,] 4.194661 3.851629
#> [4,] 4.439377 4.068333
#> [5,] 4.754171 5.262575
#> [6,] 4.364850 3.879785
#> [7,] 4.324805 5.138247
#> [8,] 4.845384 4.565327
#> [9,] 4.796440 4.204366
#> [10,] 4.276974 3.917748
#> [11,] 4.400445 4.115786
#> [12,] 4.698554 3.824106
#> [13,] 4.561735 4.073394
#> [14,] 4.201335 4.369187
#> [15,] 4.017798 3.733945
#> [16,] 4.710790 3.977855
#> AAGTCTGAGAAGATTC-400.2.3 AAGTCTGAGCAATATG-400.2.3
#> [1,] 4.592129 4.151685
#> [2,] 3.713775 4.434831
#> [3,] 3.873584 4.165169
#> [4,] 3.952892 4.320225
#> [5,] 5.211688 4.851685
#> [6,] 4.054860 4.426966
#> [7,] 5.181872 4.200000
#> [8,] 4.485987 4.855056
#> [9,] 4.069767 4.885393
#> [10,] 3.831246 4.024719
#> [11,] 4.330948 4.298876
#> [12,] 4.125224 4.691011
#> [13,] 4.209899 4.705618
#> [14,] 4.230769 3.877528
#> [15,] 4.060227 3.815730
#> [16,] 4.082886 4.701124
#> AAGTCTGCAGACGCCT-400.2.3 AAGTCTGGTGAGTGAC-400.2.3
#> [1,] 4.280788 4.567791
#> [2,] 4.167488 3.856143
#> [3,] 4.004926 4.056652
#> [4,] 4.075862 4.360917
#> [5,] 4.698522 5.253978
#> [6,] 4.267980 3.990452
#> [7,] 4.500493 5.009548
#> [8,] 4.880788 4.371738
#> [9,] 4.848276 3.973265
#> [10,] 4.291626 4.037556
#> [11,] 4.341872 4.307447
#> [12,] 4.535961 4.057288
#> [13,] 4.000000 4.177594
#> [14,] 4.042365 4.003183
#> [15,] 4.196059 3.903883
#> [16,] 4.530049 4.134309
#> AATCGGTAGTTCGATC-400.2.3 AATCGGTCACCAGATT-400.2.3
#> [1,] 4.719902 4.373109
#> [2,] 4.018428 4.296919
#> [3,] 4.120393 4.489076
#> [4,] 4.184275 4.416246
#> [5,] 5.049754 4.416246
#> [6,] 3.891278 4.617927
#> [7,] 4.316339 4.505322
#> [8,] 4.387592 4.927731
#> [9,] 3.985258 4.776471
#> [10,] 3.742015 4.374230
#> [11,] 4.116093 4.565826
#> [12,] 3.947789 4.656583
#> [13,] 4.150491 4.017927
#> [14,] 4.200246 4.256583
#> [15,] 4.092138 4.421289
#> [16,] 4.477887 4.340616
#> ACACCAATCAAACGGG-400.2.3 ACACCCTAGTTGCAGG-400.2.3
#> [1,] 4.632558 4.351277
#> [2,] 3.809967 4.236314
#> [3,] 3.772093 4.583029
#> [4,] 4.547508 4.285584
#> [5,] 4.730233 4.512774
#> [6,] 3.782724 3.962591
#> [7,] 4.541528 4.196168
#> [8,] 4.437209 4.779197
#> [9,] 4.321595 4.799270
#> [10,] 3.716279 4.394161
#> [11,] 3.732226 4.551095
#> [12,] 4.138206 4.743613
#> [13,] 4.352824 4.500000
#> [14,] 4.005980 3.981752
#> [15,] 3.914286 4.120438
#> [16,] 4.119601 4.418796
#> ACACCGGAGCGATCCC-400.2.3 ACACTGACACGGTAAG-400.2.3
#> [1,] 4.473357 4.405765
#> [2,] 4.333037 4.029933
#> [3,] 4.376554 4.609756
#> [4,] 4.311723 4.312639
#> [5,] 4.355240 4.691796
#> [6,] 4.221137 4.555432
#> [7,] 4.011545 4.300443
#> [8,] 5.012433 5.048780
#> [9,] 4.659858 4.811530
#> [10,] 4.317052 4.218404
#> [11,] 3.993783 4.334812
#> [12,] 4.512433 4.433481
#> [13,] 4.419183 4.603104
#> [14,] 4.111012 4.283814
#> [15,] 4.263766 3.921286
#> [16,] 4.645648 4.376940
#> ACACTGATCTGATTCT-400.2.3 ACAGCCGCATATGGTC-400.2.3
#> [1,] 4.253012 4.660118
#> [2,] 4.316960 4.205632
#> [3,] 4.359592 4.245580
#> [4,] 4.507878 4.115259
#> [5,] 4.298424 5.015717
#> [6,] 4.438369 3.886051
#> [7,] 4.391103 4.783235
#> [8,] 4.803522 4.704650
#> [9,] 4.423540 4.233137
#> [10,] 4.253012 3.801572
#> [11,] 4.489342 4.264571
#> [12,] 4.499537 4.148003
#> [13,] 4.628360 4.075311
#> [14,] 4.041705 4.206942
#> [15,] 4.310473 4.074656
#> [16,] 4.371640 4.784545
#> ACAGCCGCATGAAGTA-400.2.3 ACAGCTAAGTACGACG-400.2.3
#> [1,] 4.450262 4.401914
#> [2,] 4.547120 4.174641
#> [3,] 4.390052 4.088517
#> [4,] 4.117801 4.032297
#> [5,] 4.616492 4.648325
#> [6,] 4.357330 4.389952
#> [7,] 4.400524 4.364833
#> [8,] 5.188482 4.571770
#> [9,] 4.835079 4.723684
#> [10,] 4.246073 4.125598
#> [11,] 4.321990 4.175837
#> [12,] 4.387435 4.862440
#> [13,] 4.369110 4.724880
#> [14,] 4.257853 4.077751
#> [15,] 4.058901 4.113636
#> [16,] 4.548429 4.449761
#> ACATACGAGTAACCCT-400.2.3 ACATACGTCTTTAGTC-400.2.3
#> [1,] 4.694937 4.157701
#> [2,] 4.184810 4.705969
#> [3,] 4.143038 4.251290
#> [4,] 4.273418 4.170228
#> [5,] 4.694937 4.434783
#> [6,] 4.108861 4.268239
#> [7,] 4.173418 4.330877
#> [8,] 4.902532 4.865144
#> [9,] 5.313924 4.924097
#> [10,] 4.008861 4.533530
#> [11,] 4.375949 4.355195
#> [12,] 4.708861 4.330140
#> [13,] 4.811392 4.406780
#> [14,] 4.229114 4.270450
#> [15,] 4.116456 4.526898
#> [16,] 5.024051 4.109801
#> ACATCAGAGTGCTGCC-400.2.3 ACATCAGGTAGCGCAA-400.2.3
#> [1,] 4.128586 4.656351
#> [2,] 4.489242 3.765957
#> [3,] 4.498463 4.032237
#> [4,] 4.347848 4.121857
#> [5,] 4.624488 4.967763
#> [6,] 4.095287 4.101225
#> [7,] 4.009734 4.809155
#> [8,] 4.927766 4.388137
#> [9,] 4.456967 4.228885
#> [10,] 4.136270 3.960671
#> [11,] 4.235656 4.435203
#> [12,] 4.285861 4.199871
#> [13,] 4.496414 4.148936
#> [14,] 4.543033 4.350097
#> [15,] 3.984631 3.849130
#> [16,] 4.458504 4.157318
#> ACATCAGTCTCGCTTG-400.2.3 ACATCAGTCTTAACCT-400.2.3
#> [1,] 4.446371 4.150490
#> [2,] 4.224269 4.321460
#> [3,] 4.418202 4.424755
#> [4,] 4.530878 4.195013
#> [5,] 4.494041 4.506679
#> [6,] 4.665222 4.349065
#> [7,] 4.380282 4.313446
#> [8,] 4.581798 4.918077
#> [9,] 4.174431 4.818344
#> [10,] 4.582882 4.265361
#> [11,] 4.252438 4.290294
#> [12,] 4.346696 4.650935
#> [13,] 4.448537 4.396260
#> [14,] 4.147346 4.118433
#> [15,] 4.282774 4.201247
#> [16,] 4.512459 4.614426
#> ACATGGTCATCACGAT-400.2.3 ACATGGTTCAACCATG-400.2.3
#> [1,] 4.453601 3.995994
#> [2,] 4.171745 4.297276
#> [3,] 4.234765 4.170673
#> [4,] 3.921053 3.963942
#> [5,] 4.934211 4.649840
#> [6,] 4.088643 4.462340
#> [7,] 4.530471 4.604167
#> [8,] 4.432825 4.453526
#> [9,] 4.056787 4.437500
#> [10,] 4.090028 4.082532
#> [11,] 4.065789 4.284455
#> [12,] 4.448061 4.270833
#> [13,] 4.348338 4.186699
#> [14,] 4.112188 4.012821
#> [15,] 4.559557 3.979167
#> [16,] 4.479224 4.506410
#> ACCAGTAAGCTGAAAT-400.2.3 ACCAGTAAGTGGAGAA-400.2.3
#> [1,] 4.358166 4.155932
#> [2,] 3.803725 4.440678
#> [3,] 4.068768 4.101695
#> [4,] 4.345272 4.105763
#> [5,] 5.078797 4.492203
#> [6,] 4.128223 4.197288
#> [7,] 4.306590 4.311186
#> [8,] 4.704871 4.770169
#> [9,] 4.379656 4.555254
#> [10,] 4.162607 4.058983
#> [11,] 4.173352 4.394576
#> [12,] 4.196991 4.624407
#> [13,] 4.451289 4.317288
#> [14,] 4.017192 4.315932
#> [15,] 3.972063 4.092881
#> [16,] 4.029370 4.310508
#> ACCAGTACAATGGACG-400.2.3 ACCAGTAGTCAGTGGA-400.2.3
#> [1,] 4.314858 4.889606
#> [2,] 4.346698 3.701075
#> [3,] 3.957547 3.983513
#> [4,] 3.949292 4.137634
#> [5,] 4.602594 5.063799
#> [6,] 4.086085 3.663799
#> [7,] 4.088443 4.812903
#> [8,] 4.798349 4.358423
#> [9,] 4.449292 4.022222
#> [10,] 4.353774 3.834409
#> [11,] 4.340802 4.347670
#> [12,] 4.122642 3.930466
#> [13,] 4.675708 4.151971
#> [14,] 4.400943 4.203584
#> [15,] 3.536557 4.032975
#> [16,] 4.463443 4.559140
#> ACCCACTAGCGTCTAT-400.2.3 ACCGTAAGTCACTTCC-400.2.3
#> [1,] 4.417500 4.591043
#> [2,] 3.896667 3.321744
#> [3,] 3.935833 3.644078
#> [4,] 4.085000 4.176193
#> [5,] 4.823333 5.375958
#> [6,] 3.807500 3.905716
#> [7,] 4.461667 5.143783
#> [8,] 4.479167 4.010607
#> [9,] 4.189167 4.437242
#> [10,] 3.832500 3.578668
#> [11,] 3.817500 4.103712
#> [12,] 4.009167 3.779022
#> [13,] 4.410833 4.095463
#> [14,] 4.115000 4.318798
#> [15,] 3.911667 3.677077
#> [16,] 4.227500 3.733648
#> ACCTTTACAAATCCGT-400.2.3 ACGAGGAGTATGAATG-400.2.3
#> [1,] 4.356177 4.471363
#> [2,] 4.258792 3.457538
#> [3,] 4.223625 3.884134
#> [4,] 4.211903 4.282423
#> [5,] 4.505861 5.465438
#> [6,] 4.318305 3.864384
#> [7,] 4.225428 5.142857
#> [8,] 4.511271 4.094141
#> [9,] 4.276826 3.922317
#> [10,] 4.033363 3.751152
#> [11,] 4.038774 3.906517
#> [12,] 4.264202 3.701777
#> [13,] 4.429216 4.326531
#> [14,] 4.218215 4.312047
#> [15,] 4.241659 4.086899
#> [16,] 4.407574 4.356155
#> ACGATACAGACAGAGA-400.2.3 ACGATGTCATCACCCT-400.2.3
#> [1,] 4.628521 4.632752
#> [2,] 4.178404 4.565891
#> [3,] 4.184272 4.131783
#> [4,] 4.046948 4.272287
#> [5,] 4.573357 4.811047
#> [6,] 4.045775 4.281977
#> [7,] 4.231808 4.362403
#> [8,] 4.655516 5.095930
#> [9,] 4.561620 4.761628
#> [10,] 4.310446 4.482558
#> [11,] 4.275235 4.563953
#> [12,] 4.562207 4.095930
#> [13,] 4.775822 4.424419
#> [14,] 3.937793 4.208333
#> [15,] 4.547535 4.042636
#> [16,] 4.389671 4.530039
#> ACGCAGCCACTAAGTC-400.2.3 ACGCAGCCAGTTAACC-400.2.3
#> [1,] 4.124072 4.460177
#> [2,] 4.277837 4.431662
#> [3,] 4.628844 4.345133
#> [4,] 4.180276 4.361849
#> [5,] 4.398727 4.190757
#> [6,] 4.143160 4.575221
#> [7,] 4.231177 4.304818
#> [8,] 4.511135 4.889872
#> [9,] 4.346766 4.606686
#> [10,] 4.461294 4.296952
#> [11,] 4.498409 4.252704
#> [12,] 4.724284 4.658800
#> [13,] 4.180276 4.304818
#> [14,] 4.180276 4.248771
#> [15,] 4.062566 4.304818
#> [16,] 4.711559 4.831858
#> ACGCAGCTCGGCTACG-400.2.3 ACGCCAGAGGGTTCCC-400.2.3
#> [1,] 4.468461 4.532447
#> [2,] 3.476030 3.913830
#> [3,] 3.945332 3.905319
#> [4,] 4.238015 4.061170
#> [5,] 5.414634 5.347340
#> [6,] 3.874685 4.063830
#> [7,] 5.174096 4.614362
#> [8,] 4.036165 4.345745
#> [9,] 3.777965 3.715426
#> [10,] 3.835997 3.814894
#> [11,] 3.921783 4.002128
#> [12,] 3.899075 4.003723
#> [13,] 4.019344 4.138298
#> [14,] 3.841884 4.197872
#> [15,] 3.763667 4.264894
#> [16,] 4.156434 4.826064
#> ACGCCAGTCACCACCT-400.2.3 ACGCCGAAGCCACTAT-400.2.3
#> [1,] 4.237887 4.843468
#> [2,] 4.127494 3.768814
#> [3,] 4.332320 4.364238
#> [4,] 4.219077 4.173390
#> [5,] 4.753943 5.187237
#> [6,] 4.049591 3.939795
#> [7,] 4.593768 5.023480
#> [8,] 4.440243 4.212523
#> [9,] 4.139464 4.129440
#> [10,] 3.934448 3.907285
#> [11,] 4.224017 4.094521
#> [12,] 4.304769 4.022878
#> [13,] 4.271328 4.313064
#> [14,] 4.163405 4.075858
#> [15,] 3.917918 3.774232
#> [16,] 4.288999 3.828417
#> ACGGAGAAGTTATCGC-400.2.3 ACGGCCAAGATAGCAT-400.2.3
#> [1,] 4.408084 4.592114
#> [2,] 3.729236 4.560163
#> [3,] 3.998893 4.220938
#> [4,] 3.964009 4.087695
#> [5,] 4.788483 4.578518
#> [6,] 4.073090 4.356900
#> [7,] 4.651163 4.805574
#> [8,] 4.320044 4.609109
#> [9,] 4.327243 4.256968
#> [10,] 3.911960 4.254249
#> [11,] 3.872093 4.448674
#> [12,] 3.911960 4.564242
#> [13,] 4.227575 4.235894
#> [14,] 4.098007 4.284160
#> [15,] 3.904762 4.276003
#> [16,] 4.200997 4.710401
#> ACGGGCTCATCGATTG-400.2.3 ACGGGCTGTAGCGATG-400.2.3
#> [1,] 4.282086 4.232667
#> [2,] 4.389706 4.595170
#> [3,] 4.303476 4.413269
#> [4,] 4.002005 4.295378
#> [5,] 4.673797 4.585173
#> [6,] 4.285428 4.223968
#> [7,] 4.188503 4.819657
#> [8,] 4.645053 4.364061
#> [9,] 4.324866 4.202545
#> [10,] 4.233957 4.382758
#> [11,] 4.167781 4.300052
#> [12,] 4.213904 3.990003
#> [13,] 4.590241 4.061672
#> [14,] 4.079545 4.475331
#> [15,] 4.266043 4.199688
#> [16,] 4.590241 4.288107
#> ACGGGCTTCAACCAAC-400.2.3 ACGTCAAAGGTAGCTG-400.2.3
#> [1,] 4.370463 4.653082
#> [2,] 4.205257 4.337972
#> [3,] 4.735920 4.596421
#> [4,] 4.185232 4.484095
#> [5,] 4.476846 4.653082
#> [6,] 4.493116 4.296223
#> [7,] 4.181477 4.093439
#> [8,] 4.896120 4.955268
#> [9,] 4.600751 4.760437
#> [10,] 4.574468 4.255467
#> [11,] 4.450563 4.188867
#> [12,] 4.757196 4.520875
#> [13,] 4.265332 4.729622
#> [14,] 4.096370 4.337972
#> [15,] 4.093867 4.047714
#> [16,] 4.638298 4.552684
#> ACGTCAAAGTAATCCC-400.2.3 ACGTCAACAACTGGCC-400.2.3
#> [1,] 4.414498 4.355415
#> [2,] 4.301115 4.062741
#> [3,] 4.291822 4.055731
#> [4,] 4.503717 4.022783
#> [5,] 4.288104 4.974413
#> [6,] 4.334572 4.053277
#> [7,] 4.567844 4.587802
#> [8,] 4.931227 4.568174
#> [9,] 4.661710 4.428672
#> [10,] 4.122677 3.970557
#> [11,] 4.375465 4.114616
#> [12,] 4.386617 4.153873
#> [13,] 4.677509 4.433929
#> [14,] 4.302974 4.113214
#> [15,] 4.254647 3.855591
#> [16,] 4.759294 4.106905
#> ACTGAACAGCACAGGT-400.2.3 ACTGAACAGTGGAGAA-400.2.3
#> [1,] 4.186727 4.400000
#> [2,] 4.519685 3.728527
#> [3,] 3.854893 4.155486
#> [4,] 4.202475 4.143574
#> [5,] 5.016873 5.024451
#> [6,] 4.357705 3.937931
#> [7,] 4.335208 4.952978
#> [8,] 4.974128 4.497179
#> [9,] 4.844769 4.115987
#> [10,] 4.470191 4.141693
#> [11,] 4.546682 4.334169
#> [12,] 4.554556 3.825705
#> [13,] 4.365579 4.186207
#> [14,] 4.163105 4.015047
#> [15,] 4.183352 3.947335
#> [16,] 4.785152 4.469592
#> ACTGAGTTCGCAGGCT-400.2.3 ACTGCTCAGACTGGGT-400.2.3
#> [1,] 4.655215 4.407678
#> [2,] 4.390184 4.340037
#> [3,] 4.223313 4.244059
#> [4,] 4.516564 4.297989
#> [5,] 4.474847 4.419561
#> [6,] 4.505521 4.109689
#> [7,] 4.506748 4.371115
#> [8,] 4.852761 4.716636
#> [9,] 4.838037 4.573126
#> [10,] 4.325153 4.089580
#> [11,] 4.085890 4.323583
#> [12,] 4.712883 4.699269
#> [13,] 4.431902 4.664534
#> [14,] 4.321472 4.274223
#> [15,] 4.103067 4.106033
#> [16,] 4.520245 4.484461
#> ACTGTCCTCGCCTGAG-400.2.3 ACTGTCCTCTTGAGGT-400.2.3
#> [1,] 4.800986 4.182013
#> [2,] 3.635243 4.455032
#> [3,] 3.927295 4.137045
#> [4,] 4.696242 4.145610
#> [5,] 5.067776 4.850107
#> [6,] 4.096734 4.338330
#> [7,] 4.370918 4.390792
#> [8,] 4.596426 5.156317
#> [9,] 4.413432 5.026767
#> [10,] 4.086260 3.979657
#> [11,] 3.911892 4.563169
#> [12,] 4.023413 4.443255
#> [13,] 4.433148 4.555675
#> [14,] 3.860136 3.938972
#> [15,] 3.861368 3.886510
#> [16,] 4.261861 4.583512
#> ACTTTCAGTCCATGAT-400.2.3 ACTTTCATCTCGCTTG-400.2.3
#> [1,] 4.188465 4.809729
#> [2,] 3.783916 3.724754
#> [3,] 4.027214 4.024015
#> [4,] 4.098700 4.410099
#> [5,] 5.236393 5.103448
#> [6,] 4.176686 3.813424
#> [7,] 4.978473 4.870690
#> [8,] 4.352559 4.430419
#> [9,] 4.176686 4.162562
#> [10,] 4.027214 3.684729
#> [11,] 4.274574 3.877463
#> [12,] 4.193745 3.949507
#> [13,] 4.296101 4.074507
#> [14,] 4.187246 4.299877
#> [15,] 3.752640 4.194581
#> [16,] 4.093014 4.272783
#> AGAATAGAGTTCCACA-400.2.3 AGAATAGGTTTGTGTG-400.2.3
#> [1,] 4.414493 4.491718
#> [2,] 4.463768 3.849172
#> [3,] 4.193237 4.236850
#> [4,] 4.544928 4.207207
#> [5,] 4.292754 4.790177
#> [6,] 4.567150 3.938971
#> [7,] 4.914010 4.489393
#> [8,] 4.840580 4.422842
#> [9,] 4.607729 4.100552
#> [10,] 4.623188 4.013659
#> [11,] 4.457971 3.918338
#> [12,] 4.540097 4.138913
#> [13,] 4.507246 4.536763
#> [14,] 4.058937 3.995931
#> [15,] 4.306280 4.208370
#> [16,] 4.586473 4.244696
#> AGACGTTGTAGCGTCC-400.2.3 AGAGCGAAGGAGTACC-400.2.3
#> [1,] 4.491803 4.226966
#> [2,] 3.893746 3.896148
#> [3,] 3.962963 3.965449
#> [4,] 4.022465 4.299245
#> [5,] 5.624165 5.247617
#> [6,] 3.807529 4.117156
#> [7,] 5.092896 5.164416
#> [8,] 4.276867 4.407268
#> [9,] 3.956284 4.416799
#> [10,] 3.693989 4.076648
#> [11,] 3.946570 4.212073
#> [12,] 3.766242 4.028396
#> [13,] 4.099575 4.282566
#> [14,] 4.273831 4.333995
#> [15,] 4.112325 3.776410
#> [16,] 4.476017 4.282963
#> AGAGCGAGTCTCTCTG-400.2.3 AGAGCTTCATGGTAGG-400.2.3
#> [1,] 4.115021 4.326772
#> [2,] 4.477253 4.230315
#> [3,] 4.027468 4.294291
#> [4,] 3.964807 4.142717
#> [5,] 4.260944 4.433071
#> [6,] 4.204292 4.146654
#> [7,] 3.933906 4.596457
#> [8,] 5.012876 4.674213
#> [9,] 4.491845 4.498031
#> [10,] 4.433476 4.482283
#> [11,] 4.527039 4.520669
#> [12,] 4.061803 4.564961
#> [13,] 4.416309 4.217520
#> [14,] 4.136481 4.175197
#> [15,] 4.003433 4.291339
#> [16,] 4.315880 4.565945
#> AGATCTGCATTATCTC-400.2.3 AGATTGCAGAAGATTC-400.2.3
#> [1,] 4.452420 4.311665
#> [2,] 4.170201 3.805589
#> [3,] 4.151713 3.794350
#> [4,] 4.169657 4.069866
#> [5,] 4.431213 5.510328
#> [6,] 4.167482 3.908262
#> [7,] 4.015769 5.367254
#> [8,] 4.902121 4.349028
#> [9,] 4.357259 4.141252
#> [10,] 4.017945 3.895200
#> [11,] 4.015226 4.092953
#> [12,] 4.011963 3.979951
#> [13,] 4.401849 4.065006
#> [14,] 3.782490 4.376367
#> [15,] 4.139206 3.639733
#> [16,] 4.576944 4.019137
#> AGATTGCAGATCACGG-400.2.3 AGCATACAGTAGGTGC-400.2.3
#> [1,] 4.362791 4.819118
#> [2,] 4.282558 3.827941
#> [3,] 4.102326 4.294363
#> [4,] 4.195349 4.371814
#> [5,] 4.317442 4.928676
#> [6,] 4.502326 3.768873
#> [7,] 4.512791 4.276225
#> [8,] 4.856977 4.217647
#> [9,] 4.712791 3.980637
#> [10,] 4.013953 4.142647
#> [11,] 4.240698 4.516422
#> [12,] 4.305814 4.838235
#> [13,] 4.694186 4.458088
#> [14,] 4.403488 3.924020
#> [15,] 4.117442 3.967402
#> [16,] 4.598837 4.681863
#> AGCATACAGTCACGCC-400.2.3 AGCATACCAGATCCAT-400.2.3
#> [1,] 4.336461 4.230332
#> [2,] 4.193029 4.068619
#> [3,] 4.115282 4.041084
#> [4,] 4.242627 4.267483
#> [5,] 4.408847 5.103147
#> [6,] 4.396783 4.017483
#> [7,] 4.557641 4.967220
#> [8,] 4.627346 4.436626
#> [9,] 4.769437 4.146416
#> [10,] 4.234584 3.878497
#> [11,] 4.481233 4.215035
#> [12,] 4.348525 4.006119
#> [13,] 4.491957 4.363199
#> [14,] 4.243968 4.430507
#> [15,] 3.953083 3.953234
#> [16,] 4.875335 4.081294
#> AGCCTAAAGAAGGTTT-400.2.3 AGCCTAATCACTTATC-400.2.3
#> [1,] 4.698219 4.531903
#> [2,] 4.268978 4.042904
#> [3,] 4.313027 4.150165
#> [4,] 3.939082 4.141364
#> [5,] 5.029991 4.846535
#> [6,] 4.470478 4.685919
#> [7,] 4.403936 4.699670
#> [8,] 4.571696 4.486799
#> [9,] 4.298969 4.336084
#> [10,] 4.143393 4.273377
#> [11,] 3.943768 4.464796
#> [12,] 3.978444 4.395490
#> [13,] 4.090909 4.199120
#> [14,] 4.043112 4.259076
#> [15,] 3.931584 4.272277
#> [16,] 4.283037 4.385039
#> AGCCTAATCGTCCGTT-400.2.3 AGCGGTCGTGTCTGAT-400.2.3
#> [1,] 4.306695 4.134636
#> [2,] 3.670986 3.771987
#> [3,] 3.978402 4.301846
#> [4,] 4.075594 3.774159
#> [5,] 5.290137 4.629750
#> [6,] 3.946724 4.078176
#> [7,] 5.081353 4.796960
#> [8,] 4.426926 4.251900
#> [9,] 3.928006 4.359392
#> [10,] 3.843053 3.941368
#> [11,] 3.976962 4.108578
#> [12,] 4.087113 4.423453
#> [13,] 4.103672 4.195440
#> [14,] 4.275018 4.475570
#> [15,] 3.947444 4.183496
#> [16,] 4.349172 3.944625
#> AGCGTATAGTTAGGTA-400.2.3 AGCGTATCAAAGCAAT-400.2.3
#> [1,] 4.195855 4.441624
#> [2,] 3.947582 4.432741
#> [3,] 4.144657 4.016497
#> [4,] 4.170662 3.945431
#> [5,] 5.172694 4.272843
#> [6,] 3.822430 4.496193
#> [7,] 4.858594 4.335025
#> [8,] 4.283218 4.808376
#> [9,] 4.031694 4.733503
#> [10,] 3.853718 4.145939
#> [11,] 4.048354 4.046954
#> [12,] 4.377489 4.897208
#> [13,] 4.348232 4.399746
#> [14,] 4.236896 4.119289
#> [15,] 4.012597 3.911168
#> [16,] 4.115400 4.672589
#> AGCGTATGTCGCGGTT-400.2.3 AGCGTATTCTGTCTAT-400.2.3
#> [1,] 4.930755 4.606019
#> [2,] 3.523400 4.213406
#> [3,] 3.725406 3.571819
#> [4,] 4.184336 4.221614
#> [5,] 5.085482 4.374829
#> [6,] 3.904011 3.978112
#> [7,] 4.881566 4.214774
#> [8,] 4.247851 5.046512
#> [9,] 4.028653 4.615595
#> [10,] 3.841452 4.700410
#> [11,] 3.829035 4.429549
#> [12,] 3.576409 4.162791
#> [13,] 4.195320 4.268126
#> [14,] 4.368672 4.068399
#> [15,] 3.810888 3.939808
#> [16,] 4.026743 4.083447
#> AGCGTCGAGATGCCAG-400.2.3 AGCTCCTCATACCATG-400.2.3
#> [1,] 4.159250 4.508585
#> [2,] 3.815009 4.473426
#> [3,] 3.808464 4.499591
#> [4,] 4.375654 4.322159
#> [5,] 5.465969 4.851186
#> [6,] 3.806283 4.563369
#> [7,] 5.151832 4.665576
#> [8,] 4.083333 4.584628
#> [9,] 4.055846 4.439084
#> [10,] 4.085079 4.220769
#> [11,] 4.106457 4.546198
#> [12,] 3.821990 4.642682
#> [13,] 4.173211 4.282093
#> [14,] 4.400524 4.348324
#> [15,] 3.755672 4.215863
#> [16,] 3.967277 4.677024
#> AGCTCCTTCCGAGCCA-400.2.3 AGCTCCTTCCGTCAAA-400.2.3
#> [1,] 4.703362 4.032432
#> [2,] 3.782465 4.400000
#> [3,] 4.222149 4.114865
#> [4,] 4.208965 4.589189
#> [5,] 5.126566 4.541892
#> [6,] 3.851022 4.313514
#> [7,] 4.740277 4.047297
#> [8,] 4.280817 4.728378
#> [9,] 3.904417 4.535135
#> [10,] 3.894529 4.368919
#> [11,] 4.343441 3.955405
#> [12,] 4.006592 4.272973
#> [13,] 4.082399 4.556757
#> [14,] 4.188530 4.225676
#> [15,] 3.940013 4.216216
#> [16,] 4.475939 4.518919
#> AGCTCCTTCTTGTACT-400.2.3 AGCTCTCCAAGTTGTC-400.2.3
#> [1,] 4.669361 4.360104
#> [2,] 3.783982 3.652202
#> [3,] 3.722263 3.722150
#> [4,] 4.297575 3.966969
#> [5,] 5.072006 5.180699
#> [6,] 4.094783 3.918394
#> [7,] 4.509919 5.380829
#> [8,] 4.559148 4.450130
#> [9,] 3.975018 4.354275
#> [10,] 3.870683 3.882124
#> [11,] 3.891256 3.990285
#> [12,] 3.972814 3.905440
#> [13,] 4.238795 4.237047
#> [14,] 4.118295 4.305699
#> [15,] 3.934607 3.883420
#> [16,] 4.042616 4.047927
#> AGCTTGACACGACTCG-400.2.3 AGGCCGTAGGAGTCTG-400.2.3
#> [1,] 4.177225 4.335793
#> [2,] 4.313553 4.170972
#> [3,] 4.591820 4.266913
#> [4,] 4.233360 4.337023
#> [5,] 4.459503 4.164822
#> [6,] 4.208500 3.838868
#> [7,] 3.972735 4.115621
#> [8,] 4.797113 4.862239
#> [9,] 4.909383 4.569496
#> [10,] 4.251002 4.313653
#> [11,] 4.384924 4.290283
#> [12,] 4.334403 4.725707
#> [13,] 4.405774 4.624846
#> [14,] 4.318364 4.185732
#> [15,] 4.144346 4.040590
#> [16,] 4.568565 4.378844
#> AGGCCGTGTGAAGGCT-400.2.3 AGGGAGTTCAAGCCTA-400.2.3
#> [1,] 4.280650 4.581325
#> [2,] 4.541359 4.355422
#> [3,] 4.349335 3.964859
#> [4,] 4.431315 4.241968
#> [5,] 4.579025 4.758032
#> [6,] 4.336041 4.614458
#> [7,] 4.454210 4.093373
#> [8,] 4.796898 5.067269
#> [9,] 4.252585 4.616466
#> [10,] 4.485968 4.487952
#> [11,] 4.513294 4.114458
#> [12,] 4.547267 4.579317
#> [13,] 4.285820 4.553213
#> [14,] 4.242245 4.343373
#> [15,] 4.516987 4.052209
#> [16,] 4.856721 4.399598
#> AGGGATGGTAGTGAAT-400.2.3 AGGGTGACACCAGGCT-400.2.3
#> [1,] 4.644172 4.526278
#> [2,] 3.896933 4.147017
#> [3,] 4.463804 4.287642
#> [4,] 4.182822 4.394886
#> [5,] 5.105521 4.540483
#> [6,] 4.209816 4.257812
#> [7,] 4.582822 4.227983
#> [8,] 4.826994 4.830256
#> [9,] 4.402454 4.384233
#> [10,] 4.077301 4.563920
#> [11,] 4.322699 4.350852
#> [12,] 4.647853 4.670455
#> [13,] 4.925153 4.326705
#> [14,] 4.304294 4.139915
#> [15,] 4.420859 4.233665
#> [16,] 4.525153 4.454545
#> AGGGTGACAGATCTGT-400.2.3 AGGGTGACATGAGCGA-400.2.3
#> [1,] 4.945101 4.656702
#> [2,] 4.084086 4.035680
#> [3,] 4.286310 4.057377
#> [4,] 4.742182 4.345227
#> [5,] 4.611536 4.943587
#> [6,] 4.302293 4.346673
#> [7,] 4.457262 4.462874
#> [8,] 4.482279 4.379460
#> [9,] 4.245309 4.476856
#> [10,] 4.247394 4.017840
#> [11,] 4.327311 4.220829
#> [12,] 4.171647 4.271938
#> [13,] 4.351633 4.162006
#> [14,] 4.227241 4.254098
#> [15,] 4.154969 3.933944
#> [16,] 4.217512 4.332208
#> AGGTCATGTCACCTAA-400.2.3 AGGTCCGAGACAAAGG-400.2.3
#> [1,] 4.398545 4.613888
#> [2,] 3.895976 3.625334
#> [3,] 3.992295 3.902709
#> [4,] 4.195634 4.225486
#> [5,] 4.777397 5.475773
#> [6,] 4.163955 3.874475
#> [7,] 4.678510 5.111026
#> [8,] 4.350599 4.157955
#> [9,] 4.127568 3.932087
#> [10,] 4.139983 3.682182
#> [11,] 4.226884 3.897367
#> [12,] 3.870719 3.822587
#> [13,] 4.075771 3.999618
#> [14,] 4.322774 4.147272
#> [15,] 3.704195 3.681419
#> [16,] 4.229024 3.843953
#> AGGTCCGAGAGCTTCT-400.2.3 AGTAGTCGTGGACGAT-400.2.3
#> [1,] 4.113900 4.395692
#> [2,] 4.314672 4.547619
#> [3,] 4.337838 4.456916
#> [4,] 3.887066 4.312925
#> [5,] 4.533784 5.130385
#> [6,] 4.593629 4.209751
#> [7,] 4.284749 4.361678
#> [8,] 4.462355 4.591837
#> [9,] 4.515444 4.718821
#> [10,] 4.355212 4.374150
#> [11,] 4.246139 4.311791
#> [12,] 4.155405 4.054422
#> [13,] 4.252896 4.547619
#> [14,] 4.068533 4.130385
#> [15,] 4.239382 3.961451
#> [16,] 4.509653 4.461451
#> AGTAGTCTCAACACCA-400.2.3 AGTAGTCTCTTCTGGC-400.2.3
#> [1,] 4.106847 4.283323
#> [2,] 4.410083 3.735995
#> [3,] 4.283672 3.915003
#> [4,] 4.188111 3.879588
#> [5,] 4.470278 5.253059
#> [6,] 4.064710 4.009015
#> [7,] 4.757713 5.054089
#> [8,] 4.825433 4.299420
#> [9,] 4.485327 3.855763
#> [10,] 4.274643 4.072118
#> [11,] 4.806622 3.980039
#> [12,] 4.564334 4.092080
#> [13,] 4.424379 4.325821
#> [14,] 4.054929 4.169994
#> [15,] 4.501881 3.937540
#> [16,] 4.631302 4.130071
#> AGTCTTTAGATGAGAG-400.2.3 AGTCTTTTCGTAGGAG-400.2.3
#> [1,] 4.391017 4.412052
#> [2,] 4.280053 4.140065
#> [3,] 4.002642 4.060261
#> [4,] 4.437252 3.947883
#> [5,] 4.295905 4.825733
#> [6,] 4.175694 4.219055
#> [7,] 4.491413 4.245114
#> [8,] 4.760898 4.692997
#> [9,] 4.466314 4.044788
#> [10,] 4.480845 4.527687
#> [11,] 4.336856 4.006515
#> [12,] 4.159841 4.311889
#> [13,] 4.730515 4.430782
#> [14,] 3.957728 3.960912
#> [15,] 3.966975 4.188111
#> [16,] 4.505945 4.603420
#> AGTCTTTTCTGTCTCG-400.2.3 AGTGAGGCACTGAAGG-400.2.3
#> [1,] 4.256566 4.048140
#> [2,] 3.811191 4.409190
#> [3,] 4.024362 4.326039
#> [4,] 4.223068 4.051422
#> [5,] 5.314808 4.085339
#> [6,] 3.913970 3.873085
#> [7,] 5.165588 4.246171
#> [8,] 4.446517 4.921225
#> [9,] 4.063951 4.402626
#> [10,] 3.807385 4.078775
#> [11,] 4.206319 4.082057
#> [12,] 4.137800 4.017505
#> [13,] 4.231443 4.655361
#> [14,] 4.303007 3.818381
#> [15,] 3.708793 4.054705
#> [16,] 4.032737 4.675055
#> AGTGGGAAGCGATCCC-400.2.3 AGTGGGAGTTGCTCCT-400.2.3
#> [1,] 4.447667 4.445761
#> [2,] 4.151324 4.401094
#> [3,] 4.331652 4.256153
#> [4,] 4.298865 4.226071
#> [5,] 4.548550 4.342753
#> [6,] 4.517024 4.354603
#> [7,] 4.510719 4.443026
#> [8,] 5.071879 4.863263
#> [9,] 4.670870 4.393801
#> [10,] 4.230769 4.361896
#> [11,] 4.438840 4.412033
#> [12,] 4.346784 4.551504
#> [13,] 4.547289 4.422972
#> [14,] 4.442623 4.222425
#> [15,] 4.049180 4.603464
#> [16,] 4.645649 4.501367
#> AGTGTCAAGTTGAGTA-400.2.3 AGTGTCATCCTGTACC-400.2.3
#> [1,] 4.569257 4.263699
#> [2,] 3.854167 4.558219
#> [3,] 4.023649 4.211187
#> [4,] 4.336149 4.384703
#> [5,] 5.045045 4.453196
#> [6,] 3.885135 4.583333
#> [7,] 4.809122 4.202055
#> [8,] 4.429617 4.849315
#> [9,] 4.079955 4.327626
#> [10,] 3.862050 4.288813
#> [11,] 3.907658 4.311644
#> [12,] 3.868243 4.361872
#> [13,] 4.236486 4.557078
#> [14,] 3.806306 4.095890
#> [15,] 4.002815 3.963470
#> [16,] 4.173986 5.090183
#> AGTTGGTCAAGGACAC-400.2.3 ATAACGCAGAAGAAGC-400.2.3
#> [1,] 4.105493 4.322929
#> [2,] 4.611160 3.804922
#> [3,] 4.410636 3.968788
#> [4,] 4.544900 4.345138
#> [5,] 4.398431 4.988595
#> [6,] 4.198779 4.064826
#> [7,] 4.721011 5.155462
#> [8,] 4.823017 4.372149
#> [9,] 4.549259 4.269508
#> [10,] 4.505667 3.968788
#> [11,] 4.315606 4.198079
#> [12,] 4.767219 3.940576
#> [13,] 4.462075 4.200480
#> [14,] 4.387969 4.423169
#> [15,] 4.562337 3.632053
#> [16,] 4.527463 3.971188
#> ATAACGCAGATCCGAG-400.2.3 ATAGACCAGCTGAACG-400.2.3
#> [1,] 4.355674 4.235496
#> [2,] 4.564356 3.859924
#> [3,] 4.060929 4.164122
#> [4,] 4.305407 4.046947
#> [5,] 4.555979 5.251145
#> [6,] 4.161462 4.005725
#> [7,] 4.677075 4.833206
#> [8,] 4.876618 4.170992
#> [9,] 4.313024 3.967176
#> [10,] 4.158416 3.952672
#> [11,] 4.539985 4.164122
#> [12,] 4.767708 4.079008
#> [13,] 4.539985 4.213740
#> [14,] 4.183549 4.450382
#> [15,] 4.533892 3.944275
#> [16,] 4.328256 4.190076
#> ATCACGACAAGTAGTA-400.2.3 ATCACGAGTTCGCTAA-400.2.3
#> [1,] 4.069444 4.309493
#> [2,] 4.002894 3.915475
#> [3,] 4.060185 3.929779
#> [4,] 4.271991 4.143043
#> [5,] 4.565394 4.812744
#> [6,] 4.215278 4.074122
#> [7,] 5.095486 4.543563
#> [8,] 4.403356 4.749025
#> [9,] 4.165509 3.918075
#> [10,] 3.976852 4.213264
#> [11,] 3.789931 4.293888
#> [12,] 3.971644 3.905072
#> [13,] 4.436921 4.026008
#> [14,] 4.064236 4.035111
#> [15,] 4.003472 4.019506
#> [16,] 4.267361 4.266580
#> ATCACGATCCGGGTGT-400.2.3 ATCATGGAGACTAGAT-400.2.3
#> [1,] 4.629630 4.446589
#> [2,] 4.132791 4.104247
#> [3,] 4.363144 4.317889
#> [4,] 4.469738 4.290862
#> [5,] 4.304426 4.900901
#> [6,] 4.165312 4.047619
#> [7,] 4.230352 4.234234
#> [8,] 4.824752 5.126126
#> [9,] 4.583559 4.324324
#> [10,] 4.473351 4.168597
#> [11,] 4.419151 4.335907
#> [12,] 4.329720 4.137709
#> [13,] 4.588076 4.781210
#> [14,] 3.987353 4.148005
#> [15,] 4.168022 3.776062
#> [16,] 4.363144 4.666667
#> ATCATGGAGATGTAAC-400.2.3 ATCCACCTCTCTGCTG-400.2.3
#> [1,] 4.428971 4.269777
#> [2,] 3.894332 3.994929
#> [3,] 4.080476 3.779919
#> [4,] 4.241428 3.774848
#> [5,] 4.774668 5.035497
#> [6,] 3.858642 3.721095
#> [7,] 4.842547 4.088235
#> [8,] 4.347796 5.010142
#> [9,] 4.046886 4.177485
#> [10,] 3.888034 3.699797
#> [11,] 3.921624 4.253550
#> [12,] 3.841148 3.725152
#> [13,] 4.265220 4.548682
#> [14,] 4.272918 4.196755
#> [15,] 4.198740 3.788032
#> [16,] 4.241428 4.288032
#> ATCCGAACAAGGTGTG-400.2.3 ATCCGAACAATGACCT-400.2.3
#> [1,] 4.320917 4.505085
#> [2,] 4.227798 3.949718
#> [3,] 4.437317 4.109605
#> [4,] 4.145542 4.168362
#> [5,] 4.572857 4.775141
#> [6,] 4.287118 3.999435
#> [7,] 4.434040 4.221469
#> [8,] 4.540438 4.577401
#> [9,] 4.561993 4.277966
#> [10,] 4.309191 3.963842
#> [11,] 4.396448 4.072881
#> [12,] 4.339024 3.963842
#> [13,] 4.337127 4.364972
#> [14,] 4.379548 4.042373
#> [15,] 4.017072 4.040113
#> [16,] 4.363339 4.550847
#> ATCCGAACATCCGGGT-400.2.3 ATCGAGTTCAGTCAGT-400.2.3
#> [1,] 4.184925 4.743763
#> [2,] 3.909548 3.687121
#> [3,] 3.914070 3.991908
#> [4,] 4.032663 4.293999
#> [5,] 4.830653 4.492245
#> [6,] 4.022613 3.799056
#> [7,] 4.750754 4.300742
#> [8,] 4.706533 4.569791
#> [9,] 4.283417 3.976399
#> [10,] 4.158291 3.908968
#> [11,] 3.986432 3.633176
#> [12,] 3.868844 4.407957
#> [13,] 4.360804 4.291976
#> [14,] 4.129648 4.098449
#> [15,] 3.907035 4.246797
#> [16,] 4.285427 4.069454
#> ATCGAGTTCATCATTC-400.2.3 ATCTACTTCTTGTACT-400.2.3
#> [1,] 4.753189 4.472772
#> [2,] 3.935663 4.728960
#> [3,] 3.675541 3.879950
#> [4,] 4.242928 4.375000
#> [5,] 4.812535 4.504950
#> [6,] 3.716029 4.750000
#> [7,] 4.396561 4.303218
#> [8,] 4.761509 4.949257
#> [9,] 4.224626 4.240099
#> [10,] 3.448142 4.665842
#> [11,] 4.118691 4.327970
#> [12,] 3.897948 4.425743
#> [13,] 3.749861 4.493812
#> [14,] 4.491403 4.164604
#> [15,] 3.717693 4.143564
#> [16,] 4.017748 4.402228
#> ATCTGCCCATAAGACA-400.2.3 ATCTGCCCATCAGTAC-400.2.3
#> [1,] 4.600476 4.204824
#> [2,] 3.722354 4.059707
#> [3,] 3.807967 4.412416
#> [4,] 4.518430 3.993278
#> [5,] 5.021998 4.620799
#> [6,] 4.155172 4.062080
#> [7,] 4.519025 4.665876
#> [8,] 4.542212 4.498616
#> [9,] 4.049941 4.349545
#> [10,] 3.938763 4.147094
#> [11,] 3.696195 4.147885
#> [12,] 4.098098 4.359826
#> [13,] 4.485137 4.365757
#> [14,] 4.118906 4.045868
#> [15,] 3.966112 4.192566
#> [16,] 4.134364 4.364966
#> ATCTGCCGTTCGGCAC-400.2.3 ATGAGGGAGAGGTAGA-400.2.3
#> [1,] 4.183634 4.377358
#> [2,] 4.012242 4.279245
#> [3,] 4.048969 4.388679
#> [4,] 4.006765 4.117925
#> [5,] 5.073776 4.821698
#> [6,] 3.997423 4.142453
#> [7,] 4.998067 4.121698
#> [8,] 4.263853 4.798113
#> [9,] 4.186534 4.432075
#> [10,] 4.043814 4.138679
#> [11,] 4.282861 4.202830
#> [12,] 4.014497 4.204717
#> [13,] 4.241946 4.392453
#> [14,] 4.435889 4.135849
#> [15,] 3.926869 4.186792
#> [16,] 4.038338 4.185849
#> ATGAGGGAGTCACGCC-400.2.3 ATGAGGGGTGCCTGCA-400.2.3
#> [1,] 4.433618 4.506884
#> [2,] 4.534714 3.624531
#> [3,] 4.380024 3.772215
#> [4,] 4.495737 3.993742
#> [5,] 4.406821 5.193367
#> [6,] 4.500609 3.800375
#> [7,] 4.436054 4.698999
#> [8,] 4.587089 4.297247
#> [9,] 4.507917 4.292240
#> [10,] 4.378806 3.600125
#> [11,] 4.269184 3.786608
#> [12,] 4.325213 4.187735
#> [13,] 4.567600 4.290989
#> [14,] 4.907430 4.444931
#> [15,] 3.808770 3.738423
#> [16,] 4.330085 3.921777
#> ATGAGGGTCTGGGCCA-400.2.3 ATGCGATCACAGGTTT-400.2.3
#> [1,] 4.320293 4.882957
#> [2,] 4.004075 3.228953
#> [3,] 4.355338 3.752053
#> [4,] 4.220864 4.157084
#> [5,] 4.273024 4.763860
#> [6,] 4.044825 3.649897
#> [7,] 4.416463 4.820842
#> [8,] 4.594132 4.014887
#> [9,] 4.539527 4.227413
#> [10,] 3.880196 3.554415
#> [11,] 4.191524 3.874230
#> [12,] 4.024450 4.276181
#> [13,] 4.359413 4.222793
#> [14,] 4.082315 4.452772
#> [15,] 4.015485 4.381417
#> [16,] 4.623472 4.149897
#> ATGGGAGCATTGCGGC-400.2.3 ATGTGTGCAATCTGCA-400.2.3
#> [1,] 4.449584 4.371542
#> [2,] 4.344126 4.540514
#> [3,] 4.296947 4.781621
#> [4,] 3.964847 4.143281
#> [5,] 4.595745 4.535573
#> [6,] 4.610546 4.125494
#> [7,] 4.345051 4.262846
#> [8,] 4.214616 4.895257
#> [9,] 4.421832 4.390316
#> [10,] 4.362627 4.375494
#> [11,] 4.298797 4.152174
#> [12,] 4.530065 4.341897
#> [13,] 4.728030 4.309289
#> [14,] 4.482886 4.084980
#> [15,] 4.005550 4.191700
#> [16,] 4.257169 4.929842
#> ATGTGTGGTTATGCGT-400.2.3 ATTACTCCAAAGCGGT-400.2.3
#> [1,] 4.424373 4.428368
#> [2,] 3.716129 4.309337
#> [3,] 3.769892 4.126158
#> [4,] 4.142652 4.301497
#> [5,] 5.019355 4.554526
#> [6,] 4.154839 4.049893
#> [7,] 4.577778 3.957947
#> [8,] 4.394982 4.948681
#> [9,] 4.564158 4.908054
#> [10,] 3.861649 4.135424
#> [11,] 3.921864 4.103350
#> [12,] 4.076703 4.391304
#> [13,] 4.644444 4.436921
#> [14,] 4.481004 4.275837
#> [15,] 3.845161 4.160371
#> [16,] 4.116846 4.439772
#> ATTATCCTCCGAATGT-400.2.3 ATTGGACCAGGTCCAC-400.2.3
#> [1,] 4.393950 4.488120
#> [2,] 3.681323 4.613636
#> [3,] 3.629265 4.189050
#> [4,] 4.276820 4.257231
#> [5,] 5.948646 4.804236
#> [6,] 3.707000 4.301653
#> [7,] 6.053816 4.557335
#> [8,] 3.787548 4.818698
#> [9,] 3.677805 4.457645
#> [10,] 3.812170 4.232438
#> [11,] 3.900809 4.591942
#> [12,] 3.774182 4.212810
#> [13,] 4.062962 3.994318
#> [14,] 4.196975 4.234504
#> [15,] 3.393247 4.097624
#> [16,] 3.821316 4.631715
#> ATTGGACGTCCCGACA-400.2.3 ATTGGACGTTGGTTTG-400.2.3
#> [1,] 4.457447 4.548350
#> [2,] 4.041223 3.328894
#> [3,] 4.376330 3.633468
#> [4,] 4.633865 4.629994
#> [5,] 4.864805 5.190504
#> [6,] 4.164450 3.685582
#> [7,] 4.417996 4.841922
#> [8,] 4.554078 4.431384
#> [9,] 4.341755 4.113492
#> [10,] 4.076241 3.643891
#> [11,] 4.296543 3.795020
#> [12,] 4.265514 3.892878
#> [13,] 4.094415 4.314418
#> [14,] 4.402039 3.949624
#> [15,] 4.074025 3.739433
#> [16,] 4.239362 3.858715
#> ATTGGACTCCCTTGTG-400.2.3 ATTTCTGAGGACTGGT-400.2.3
#> [1,] 4.226939 4.116544
#> [2,] 4.308571 4.286001
#> [3,] 4.149388 4.090422
#> [4,] 4.445714 4.042867
#> [5,] 4.795102 4.756196
#> [6,] 4.444082 3.782987
#> [7,] 4.351837 4.633624
#> [8,] 4.831020 4.703282
#> [9,] 4.763265 4.540522
#> [10,] 4.208163 4.194910
#> [11,] 4.466939 4.186872
#> [12,] 4.356735 4.300737
#> [13,] 4.480000 4.318821
#> [14,] 4.135510 4.410583
#> [15,] 4.213878 3.738781
#> [16,] 4.422857 4.443403
#> ATTTCTGTCCACGTTC-400.2.3 ATTTCTGTCCTAGGGC-400.2.3
#> [1,] 4.469716 4.219979
#> [2,] 3.959209 4.126461
#> [3,] 4.118665 4.484591
#> [4,] 3.901112 4.222104
#> [5,] 4.490729 4.427205
#> [6,] 3.772559 4.365569
#> [7,] 4.046972 4.465462
#> [8,] 4.624227 4.727949
#> [9,] 4.605686 4.995749
#> [10,] 3.793572 4.183847
#> [11,] 4.046972 4.417641
#> [12,] 4.557478 4.446334
#> [13,] 4.845488 4.524973
#> [14,] 3.830655 4.466525
#> [15,] 4.216316 3.962806
#> [16,] 4.504326 4.819341
#> CAACCTCCACACATGT-400.2.3 CAACCTCTCCTCAACC-400.2.3
#> [1,] 4.516576 4.373793
#> [2,] 3.612417 4.401379
#> [3,] 3.760096 4.302069
#> [4,] 4.567209 4.387586
#> [5,] 5.082580 4.568276
#> [6,] 4.074744 4.401379
#> [7,] 4.787221 3.902069
#> [8,] 4.437010 4.986207
#> [9,] 4.518385 4.605517
#> [10,] 3.960820 4.721379
#> [11,] 3.731766 4.286897
#> [12,] 4.156721 4.471724
#> [13,] 4.611212 4.219310
#> [14,] 4.421941 4.144828
#> [15,] 3.957203 4.475862
#> [16,] 4.317661 4.666207
#> CAACTAGAGCAGCGTA-400.2.3 CAAGAAAAGAGTACAT-400.2.3
#> [1,] 4.310393 4.595838
#> [2,] 4.319522 4.414020
#> [3,] 4.241573 4.235487
#> [4,] 3.601826 4.048193
#> [5,] 4.620787 4.688938
#> [6,] 4.053371 4.534502
#> [7,] 3.834270 4.355969
#> [8,] 5.155197 4.808324
#> [9,] 4.335674 4.676889
#> [10,] 4.419944 4.394304
#> [11,] 4.565309 4.329682
#> [12,] 4.145365 4.503834
#> [13,] 4.464888 4.501643
#> [14,] 4.159410 4.220153
#> [15,] 4.002809 3.923330
#> [16,] 4.393258 4.514786
#> CAAGAAAGTACCATCA-400.2.3 CAAGATCAGACCACGA-400.2.3
#> [1,] 4.490028 4.600473
#> [2,] 3.883191 3.719858
#> [3,] 3.823362 4.135934
#> [4,] 4.022080 4.258865
#> [5,] 5.362536 4.764775
#> [6,] 3.961538 3.901891
#> [7,] 5.082621 4.052009
#> [8,] 4.097578 4.392435
#> [9,] 4.122507 4.245863
#> [10,] 4.077635 4.141844
#> [11,] 3.891026 3.958629
#> [12,] 3.874644 4.241135
#> [13,] 4.249288 4.508274
#> [14,] 4.273504 4.236407
#> [15,] 3.759972 4.274232
#> [16,] 3.935185 4.228132
#> CAAGATCAGTTCCACA-400.2.3 CAAGGCCAGAAGAAGC-400.2.3
#> [1,] 4.330793 4.629226
#> [2,] 3.882622 4.407852
#> [3,] 4.016006 3.812432
#> [4,] 3.875762 4.184297
#> [5,] 4.553354 4.704471
#> [6,] 4.387195 4.414395
#> [7,] 4.641768 4.140676
#> [8,] 4.324695 4.828790
#> [9,] 4.401677 4.076336
#> [10,] 3.998476 3.921483
#> [11,] 4.432927 3.922574
#> [12,] 4.455030 4.416576
#> [13,] 4.121951 4.340240
#> [14,] 4.064024 3.960742
#> [15,] 3.875000 3.820065
#> [16,] 4.029726 4.284624
#> CAAGTTGGTCTGCGGT-400.2.3 CACACCTAGCTACCGC-400.2.3
#> [1,] 4.514964 4.450465
#> [2,] 4.301342 4.046524
#> [3,] 3.814241 4.019704
#> [4,] 4.185759 4.066776
#> [5,] 4.936017 4.916256
#> [6,] 4.271414 3.886700
#> [7,] 4.117647 4.685276
#> [8,] 4.971104 4.657909
#> [9,] 4.876161 4.171866
#> [10,] 4.330237 3.904215
#> [11,] 4.375645 4.403941
#> [12,] 4.310630 4.075534
#> [13,] 4.372549 4.187192
#> [14,] 4.584107 4.437876
#> [15,] 4.130031 4.078270
#> [16,] 4.509804 4.283525
#> CACACCTCATGTAAGA-400.2.3 CACACCTCATTAACCG-400.2.3
#> [1,] 4.156098 4.824747
#> [2,] 4.144390 3.619192
#> [3,] 3.775610 3.900505
#> [4,] 3.782439 4.516667
#> [5,] 5.206829 4.884848
#> [6,] 3.566829 3.833333
#> [7,] 4.651707 4.490909
#> [8,] 4.644878 4.272727
#> [9,] 4.208780 3.939899
#> [10,] 3.973659 3.852020
#> [11,] 4.289756 3.783333
#> [12,] 3.866341 3.990909
#> [13,] 4.040976 4.286364
#> [14,] 4.797073 3.939899
#> [15,] 3.632195 4.349495
#> [16,] 3.966829 4.094949
#> CACACTCCAAGCCGCT-400.2.3 CACAGGCAGATCCCAT-400.2.3
#> [1,] 4.370370 4.755467
#> [2,] 4.493177 3.821074
#> [3,] 4.071150 4.237243
#> [4,] 4.357700 4.111332
#> [5,] 4.447368 5.049702
#> [6,] 4.447368 3.731610
#> [7,] 4.267057 4.490391
#> [8,] 4.678363 4.495030
#> [9,] 4.692008 4.157058
#> [10,] 4.381092 4.125911
#> [11,] 4.228070 4.102717
#> [12,] 4.466862 3.777999
#> [13,] 4.313840 4.049039
#> [14,] 4.242690 4.094102
#> [15,] 4.212476 4.222001
#> [16,] 4.706628 4.560636
#> CACAGTAGTCATATCG-400.2.3 CACAGTAGTCGGCATC-400.2.3
#> [1,] 4.305186 4.469585
#> [2,] 3.990027 4.116469
#> [3,] 4.293218 4.275223
#> [4,] 4.055186 4.122404
#> [5,] 5.061835 4.620178
#> [6,] 4.202128 4.635015
#> [7,] 5.046543 4.522997
#> [8,] 4.293218 4.753709
#> [9,] 4.208112 4.717359
#> [10,] 4.190824 4.196588
#> [11,] 4.172872 4.568249
#> [12,] 4.071809 4.434718
#> [13,] 4.287899 4.034866
#> [14,] 4.434176 4.200297
#> [15,] 3.870346 4.112760
#> [16,] 4.144282 4.321217
#> CACATAGCACACTGCG-400.2.3 CACATAGCACATTTCT-400.2.3
#> [1,] 4.589941 4.852064
#> [2,] 3.736095 4.256881
#> [3,] 3.968639 4.252294
#> [4,] 4.088757 4.049312
#> [5,] 4.716568 4.427752
#> [6,] 4.094083 4.063073
#> [7,] 4.644379 3.918578
#> [8,] 4.496450 5.154817
#> [9,] 4.314793 4.474771
#> [10,] 3.781065 4.285550
#> [11,] 4.359172 4.317661
#> [12,] 4.231953 4.250000
#> [13,] 4.236095 4.752294
#> [14,] 3.947929 4.391055
#> [15,] 3.865680 3.881881
#> [16,] 4.076923 3.920872
#> CACATTTGTAGGCATG-400.2.3 CACCACTAGTACGCCC-400.2.3
#> [1,] 4.386080 4.794809
#> [2,] 3.571089 3.678832
#> [3,] 3.955979 4.193836
#> [4,] 4.248662 4.315491
#> [5,] 5.255205 4.819140
#> [6,] 3.882808 4.146796
#> [7,] 5.135039 4.795620
#> [8,] 4.463415 3.836172
#> [9,] 4.275431 4.347932
#> [10,] 3.726353 3.922952
#> [11,] 4.069601 3.845093
#> [12,] 3.992861 4.197080
#> [13,] 4.299227 4.345499
#> [14,] 4.322427 4.580697
#> [15,] 4.058894 3.843471
#> [16,] 4.404521 3.900243
#> CACCACTTCATCGCTC-400.2.3 CACCAGGTCCTCCTAG-400.2.3
#> [1,] 4.344435 4.610495
#> [2,] 3.860276 3.700665
#> [3,] 4.166531 4.047302
#> [4,] 4.319253 4.744272
#> [5,] 4.533712 4.935698
#> [6,] 4.171405 3.885440
#> [7,] 4.922827 4.433851
#> [8,] 4.412673 4.508500
#> [9,] 4.130788 4.200296
#> [10,] 3.808286 3.868441
#> [11,] 4.042242 3.954176
#> [12,] 3.954509 3.988914
#> [13,] 4.320877 4.599409
#> [14,] 4.186840 4.182557
#> [15,] 3.861089 4.084257
#> [16,] 4.158408 4.290466
#> CACCTTGCACAGATTC-400.2.3 CACCTTGGTAGAGTGC-400.2.3
#> [1,] 4.295902 4.176733
#> [2,] 4.520492 4.409901
#> [3,] 4.154918 4.335644
#> [4,] 4.071311 4.038119
#> [5,] 4.514754 4.277228
#> [6,] 4.236885 4.151485
#> [7,] 4.485246 3.985149
#> [8,] 5.212295 4.818317
#> [9,] 4.463115 4.350495
#> [10,] 4.646721 4.137624
#> [11,] 4.526230 4.301485
#> [12,] 4.663934 4.432178
#> [13,] 4.209836 4.309901
#> [14,] 4.052459 4.136634
#> [15,] 3.868852 4.209901
#> [16,] 4.225410 4.429703
#> CACTCCAGTCAAAGCG-400.2.3 CAGAATCCACAAGCCC-400.2.3
#> [1,] 4.314815 4.473623
#> [2,] 3.871823 4.090270
#> [3,] 4.070806 4.148886
#> [4,] 4.433914 4.436108
#> [5,] 4.998548 4.328253
#> [6,] 4.098402 4.099648
#> [7,] 4.870007 4.218054
#> [8,] 4.198257 4.946073
#> [9,] 4.123457 4.480657
#> [10,] 3.997821 4.339977
#> [11,] 4.249818 4.099648
#> [12,] 3.889615 4.406800
#> [13,] 4.236020 4.519343
#> [14,] 4.312999 4.309496
#> [15,] 3.901598 4.007034
#> [16,] 4.055192 4.848769
#> CAGAATCCAGCTGCAC-400.2.3 CAGAATCGTGGGTATG-400.2.3
#> [1,] 4.780588 4.560304
#> [2,] 3.956687 3.861827
#> [3,] 4.033829 3.920960
#> [4,] 4.319317 4.313817
#> [5,] 5.248814 5.012295
#> [6,] 4.089472 3.731265
#> [7,] 4.689219 4.708431
#> [8,] 4.204553 4.634075
#> [9,] 4.144483 4.073770
#> [10,] 3.697123 3.705504
#> [11,] 4.099905 3.882319
#> [12,] 3.901676 4.002342
#> [13,] 4.141954 4.481850
#> [14,] 4.153968 4.200234
#> [15,] 4.103067 3.978337
#> [16,] 4.408789 3.926815
#> CAGAGAGGTACGCACC-400.2.3 CAGAGAGGTTCTGTTT-400.2.3
#> [1,] 4.358223 4.604853
#> [2,] 4.566163 4.055459
#> [3,] 4.319471 4.062392
#> [4,] 4.261815 4.380849
#> [5,] 4.804348 4.622617
#> [6,] 4.663516 4.089688
#> [7,] 4.304348 4.581889
#> [8,] 4.990548 4.423744
#> [9,] 5.094518 4.503466
#> [10,] 4.293951 4.162045
#> [11,] 4.558601 4.369584
#> [12,] 4.584121 4.142981
#> [13,] 4.932892 4.455806
#> [14,] 4.068053 4.260399
#> [15,] 4.208885 3.975303
#> [16,] 4.421550 4.188042
#> CAGATCAGTAGCTAAA-400.2.3 CAGCAGCGTTAGGGTG-400.2.3
#> [1,] 4.506627 4.366097
#> [2,] 3.515464 4.189459
#> [3,] 4.067010 4.539886
#> [4,] 4.005891 4.187322
#> [5,] 4.882180 4.858974
#> [6,] 4.019146 4.880342
#> [7,] 4.804124 4.418091
#> [8,] 4.183358 4.804843
#> [9,] 4.332106 4.461538
#> [10,] 3.727541 4.451567
#> [11,] 4.251105 4.846154
#> [12,] 4.331370 4.418091
#> [13,] 4.184094 3.933048
#> [14,] 4.224595 4.409544
#> [15,] 3.611929 4.353276
#> [16,] 3.977172 4.455840
#> CAGCATAAGATATGCA-400.2.3 CAGCATAGTATTAGCC-400.2.3
#> [1,] 4.376952 4.561963
#> [2,] 3.967286 4.585276
#> [3,] 4.089963 4.087117
#> [4,] 3.992565 3.904294
#> [5,] 4.614870 4.711656
#> [6,] 3.992565 4.600000
#> [7,] 4.204461 4.516564
#> [8,] 4.628253 4.871166
#> [9,] 4.082528 4.501840
#> [10,] 4.222305 4.604908
#> [11,] 4.160595 4.322699
#> [12,] 4.102602 4.310429
#> [13,] 4.098141 4.294479
#> [14,] 4.159851 3.910429
#> [15,] 4.258736 3.760736
#> [16,] 4.683271 4.198773
#> CAGCATATCCCTAACC-400.2.3 CAGCCGACAAGTTGTC-400.2.3
#> [1,] 4.311580 4.180465
#> [2,] 4.118682 4.053488
#> [3,] 4.255918 3.998605
#> [4,] 4.295905 4.151163
#> [5,] 5.099168 4.946512
#> [6,] 4.076775 4.254884
#> [7,] 4.785988 4.767907
#> [8,] 4.411068 4.325581
#> [9,] 4.165707 4.170233
#> [10,] 4.105566 3.997209
#> [11,] 4.272873 4.175814
#> [12,] 4.366923 4.127907
#> [13,] 4.247281 4.338140
#> [14,] 4.188740 3.988372
#> [15,] 4.133397 3.827907
#> [16,] 4.491683 4.120465
#> CAGCCGACAGGCTCAC-400.2.3 CAGCGACCAAGCCGCT-400.2.3
#> [1,] 4.388753 4.400568
#> [2,] 4.042380 4.121212
#> [3,] 4.346373 4.071023
#> [4,] 4.052975 3.832386
#> [5,] 4.665852 4.759470
#> [6,] 4.112469 4.205492
#> [7,] 4.346373 4.356061
#> [8,] 4.743276 4.408144
#> [9,] 4.291769 4.472538
#> [10,] 4.209454 4.079545
#> [11,] 4.116544 4.196023
#> [12,] 4.184189 4.032197
#> [13,] 4.383863 4.541667
#> [14,] 4.189079 4.321023
#> [15,] 3.932355 3.970644
#> [16,] 4.245314 4.568182
#> CAGCGACTCTGATTCT-400.2.3 CAGCTAACAGCTGTTA-400.2.3
#> [1,] 4.381895 4.713277
#> [2,] 3.969354 3.469633
#> [3,] 4.161245 4.225282
#> [4,] 4.368223 4.156073
#> [5,] 5.185761 5.012712
#> [6,] 4.102310 3.811441
#> [7,] 4.883074 4.870056
#> [8,] 4.250354 4.071328
#> [9,] 3.929750 4.109463
#> [10,] 4.114569 3.990819
#> [11,] 4.114097 4.220339
#> [12,] 4.069778 4.269068
#> [13,] 4.267798 4.163136
#> [14,] 4.368694 4.279661
#> [15,] 3.931165 3.598164
#> [16,] 4.148043 4.133475
#> CAGCTGGAGCGTGTCC-400.2.3 CAGGTGCAGCGATGAC-400.2.3
#> [1,] 4.740028 4.579088
#> [2,] 3.579772 3.498660
#> [3,] 3.942308 4.063003
#> [4,] 4.383191 4.380027
#> [5,] 4.745014 5.003351
#> [6,] 4.160256 3.770107
#> [7,] 4.378917 4.655496
#> [8,] 4.574074 4.508713
#> [9,] 4.430199 4.096515
#> [10,] 3.850427 3.720509
#> [11,] 4.071937 4.018097
#> [12,] 4.054843 4.217158
#> [13,] 3.970085 4.101877
#> [14,] 4.430912 4.121984
#> [15,] 3.965100 3.733914
#> [16,] 3.754274 4.089812
#> CAGGTGCCACTGTGTA-400.2.3 CAGGTGCGTCAATGTC-400.2.3
#> [1,] 4.481097 4.564012
#> [2,] 3.870794 4.115927
#> [3,] 4.319900 4.515121
#> [4,] 4.167844 4.421371
#> [5,] 5.090569 4.568044
#> [6,] 4.007478 4.394657
#> [7,] 4.718737 4.365423
#> [8,] 4.236394 4.943548
#> [9,] 4.079767 4.539819
#> [10,] 4.005401 4.392137
#> [11,] 4.135854 4.561996
#> [12,] 4.377233 4.519153
#> [13,] 4.240964 4.117944
#> [14,] 4.113004 4.067540
#> [15,] 4.218945 4.063508
#> [16,] 4.265891 4.316532
#> CAGGTGCTCACTGGGC-400.2.3 CAGTAACTCCTTCAAT-400.2.3
#> [1,] 4.395750 4.216123
#> [2,] 3.803453 4.335334
#> [3,] 4.179947 4.281304
#> [4,] 4.096946 4.393654
#> [5,] 5.054449 4.741852
#> [6,] 4.047809 4.855918
#> [7,] 4.790837 4.513722
#> [8,] 4.357902 4.950257
#> [9,] 3.940903 4.729846
#> [10,] 4.034529 4.301887
#> [11,] 3.810757 4.563465
#> [12,] 3.629482 4.343053
#> [13,] 4.122178 4.143225
#> [14,] 4.147410 4.087479
#> [15,] 4.069721 4.268439
#> [16,] 4.641434 4.671527
#> CATATGGGTCGACTGC-400.2.3 CATATGGTCACGATGT-400.2.3
#> [1,] 4.492998 4.305484
#> [2,] 3.902801 4.040492
#> [3,] 4.047776 3.980523
#> [4,] 4.191928 4.159918
#> [5,] 4.811367 5.010251
#> [6,] 3.893328 4.010251
#> [7,] 4.481054 4.736033
#> [8,] 4.335667 4.294721
#> [9,] 4.370264 4.048180
#> [10,] 3.919687 4.003588
#> [11,] 4.228995 4.061507
#> [12,] 4.121087 4.082522
#> [13,] 4.278830 4.375192
#> [14,] 4.322488 4.267555
#> [15,] 3.987644 4.077396
#> [16,] 4.046540 4.226550
#> CATCAAGTCGAATGCT-400.2.3 CATCGAACAGCCAGAA-400.2.3
#> [1,] 4.583986 4.388133
#> [2,] 4.127046 3.717474
#> [3,] 4.258719 3.879695
#> [4,] 4.080071 4.373435
#> [5,] 4.433808 4.840501
#> [6,] 4.158719 4.083288
#> [7,] 4.155160 4.892760
#> [8,] 4.760854 4.451824
#> [9,] 4.357295 4.240610
#> [10,] 4.141281 3.849755
#> [11,] 4.228114 4.089820
#> [12,] 4.000356 3.769189
#> [13,] 4.343060 4.259662
#> [14,] 4.285409 4.329886
#> [15,] 4.039146 3.825259
#> [16,] 4.197865 4.045727
#> CATCGGGCAGCTTAAC-400.2.3 CATCGGGTCAAGGCTT-400.2.3
#> [1,] 4.372134 4.194518
#> [2,] 4.084656 4.117595
#> [3,] 4.365961 4.425287
#> [4,] 4.277778 4.279399
#> [5,] 4.727513 4.620690
#> [6,] 4.331570 4.619805
#> [7,] 4.229277 4.663130
#> [8,] 4.820988 4.933687
#> [9,] 4.342152 3.962865
#> [10,] 4.506173 4.389920
#> [11,] 4.469136 4.535809
#> [12,] 4.433862 4.502210
#> [13,] 4.171076 4.027409
#> [14,] 4.087302 4.375774
#> [15,] 4.093474 3.930150
#> [16,] 4.336861 4.287356
#> CATGACAAGTGCGTGA-400.2.3 CATGACACATGCTGGC-400.2.3
#> [1,] 4.355851 4.191657
#> [2,] 3.670745 4.129988
#> [3,] 4.531383 4.354897
#> [4,] 3.961170 4.160822
#> [5,] 4.621277 4.795042
#> [6,] 3.997872 4.548368
#> [7,] 4.485638 4.715236
#> [8,] 4.159043 4.957678
#> [9,] 4.221277 4.584643
#> [10,] 3.860106 4.420798
#> [11,] 4.174468 4.400242
#> [12,] 4.219681 4.413543
#> [13,] 4.151064 4.079202
#> [14,] 4.242021 4.110641
#> [15,] 4.186170 4.086457
#> [16,] 4.468617 4.440750
#> CATGACAGTGCAACTT-400.2.3 CATGGCGCAAATTGCC-400.2.3
#> [1,] 4.274357 4.513052
#> [2,] 4.090533 3.664699
#> [3,] 4.197151 3.958670
#> [4,] 4.157629 4.343692
#> [5,] 4.934283 5.198260
#> [6,] 4.083180 3.875078
#> [7,] 4.855239 5.149472
#> [8,] 4.636949 4.301429
#> [9,] 4.087776 3.981044
#> [10,] 4.035386 3.788689
#> [11,] 4.237132 4.164077
#> [12,] 4.131434 3.816035
#> [13,] 4.268382 4.165942
#> [14,] 4.246324 4.360162
#> [15,] 3.945313 3.660348
#> [16,] 4.089154 3.897141
#> CATGGCGTCTAACGGT-400.2.3 CATTCGCAGCGAAGGG-400.2.3
#> [1,] 4.887781 4.381649
#> [2,] 3.577485 4.457447
#> [3,] 3.924118 4.335106
#> [4,] 4.283221 4.301862
#> [5,] 4.992519 4.864362
#> [6,] 4.012825 4.611702
#> [7,] 4.906662 4.179521
#> [8,] 4.478090 4.748670
#> [9,] 4.558960 4.765957
#> [10,] 3.788742 4.061170
#> [11,] 4.240470 4.408245
#> [12,] 4.606698 4.414894
#> [13,] 4.302458 4.755319
#> [14,] 3.978269 4.113032
#> [15,] 3.818668 3.969415
#> [16,] 4.387602 4.589096
#> CCAATCCGTAGTGAAT-400.2.3 CCAATCCTCTACTTAC-400.2.3
#> [1,] 4.465558 4.244281
#> [2,] 3.812352 4.001634
#> [3,] 3.990499 3.936275
#> [4,] 4.239905 4.221405
#> [5,] 5.015044 5.158497
#> [6,] 4.014252 4.168301
#> [7,] 4.954078 4.565359
#> [8,] 4.332542 4.634804
#> [9,] 4.247823 4.449346
#> [10,] 3.760095 3.959150
#> [11,] 4.153603 3.834967
#> [12,] 4.083927 4.102124
#> [13,] 3.973872 4.175654
#> [14,] 4.186857 4.392157
#> [15,] 3.665875 3.825163
#> [16,] 4.027712 4.194444
#> CCACCTATCTACCAGA-400.2.3 CCACGGATCACCCTCA-400.2.3
#> [1,] 4.393387 4.398601
#> [2,] 3.669327 3.721445
#> [3,] 4.067275 4.173660
#> [4,] 3.920753 4.242424
#> [5,] 4.396807 4.858974
#> [6,] 3.982326 4.073427
#> [7,] 4.555872 4.650350
#> [8,] 4.314139 4.575758
#> [9,] 4.444128 4.277389
#> [10,] 3.716078 3.705128
#> [11,] 3.993729 3.833333
#> [12,] 4.297605 3.966200
#> [13,] 4.242303 4.202797
#> [14,] 4.601482 3.986014
#> [15,] 4.309578 3.837995
#> [16,] 4.181300 4.312354
#> CCACGGATCCTAAGTG-400.2.3 CCACTACCACTCGACG-400.2.3
#> [1,] 4.192238 4.236994
#> [2,] 4.119134 4.217726
#> [3,] 4.223827 4.102762
#> [4,] 4.199458 4.289017
#> [5,] 4.840253 4.977521
#> [6,] 4.305054 4.322415
#> [7,] 4.527978 4.640976
#> [8,] 4.284296 4.285806
#> [9,] 4.219314 4.256262
#> [10,] 4.425993 4.228003
#> [11,] 4.321300 3.941554
#> [12,] 4.282491 4.385999
#> [13,] 4.079422 4.368015
#> [14,] 4.592058 4.028902
#> [15,] 4.049639 3.752730
#> [16,] 4.448556 4.028902
#> CCACTACTCACTGGGC-400.2.3 CCAGCGAAGCGTTCCG-400.2.3
#> [1,] 4.834550 4.787037
#> [2,] 3.482563 3.711538
#> [3,] 3.740470 3.852564
#> [4,] 4.135442 4.148860
#> [5,] 5.304136 4.908832
#> [6,] 3.723439 3.698718
#> [7,] 4.667478 4.589031
#> [8,] 4.018654 4.305556
#> [9,] 4.125710 4.448006
#> [10,] 3.586375 3.856125
#> [11,] 4.146796 3.836182
#> [12,] 3.747770 4.353276
#> [13,] 4.082725 4.236467
#> [14,] 4.461476 4.422365
#> [15,] 3.874290 3.983618
#> [16,] 4.617194 4.051994
#> CCATGTCCACCATCCT-400.2.3 CCCAATCCACCGAAAG-400.2.3
#> [1,] 4.388509 4.587654
#> [2,] 4.056088 4.218107
#> [3,] 4.067031 4.295473
#> [4,] 4.155267 3.970370
#> [5,] 4.549248 4.720165
#> [6,] 4.043092 3.922634
#> [7,] 4.261970 4.282305
#> [8,] 4.499316 4.558025
#> [9,] 4.183311 4.292181
#> [10,] 4.103967 4.038683
#> [11,] 4.228454 4.169547
#> [12,] 4.392613 4.210700
#> [13,] 4.138167 4.561317
#> [14,] 4.473324 4.033745
#> [15,] 4.204514 4.180247
#> [16,] 4.221614 4.869136
#> CCCATACTCCCATTAT-400.2.3 CCCTCCTCAGTATGCT-400.2.3
#> [1,] 4.290201 4.415160
#> [2,] 4.242462 3.809458
#> [3,] 4.272613 4.051113
#> [4,] 4.316583 3.987830
#> [5,] 4.743719 4.950974
#> [6,] 4.497487 3.857789
#> [7,] 4.131910 4.604312
#> [8,] 5.100503 4.585188
#> [9,] 4.635678 4.122045
#> [10,] 4.207286 3.765647
#> [11,] 4.863065 4.278164
#> [12,] 4.644472 4.125174
#> [13,] 4.466080 4.135257
#> [14,] 4.199749 4.608136
#> [15,] 3.974874 3.712796
#> [16,] 4.781407 4.061892
#> CCGGTAGCAGCTGTGC-400.2.3 CCGGTAGGTTGTACAC-400.2.3
#> [1,] 4.079848 4.454361
#> [2,] 4.506790 3.999493
#> [3,] 4.330798 4.093306
#> [4,] 4.165128 4.022312
#> [5,] 4.530147 5.122211
#> [6,] 4.507876 3.971095
#> [7,] 4.255296 4.389959
#> [8,] 4.863661 4.595842
#> [9,] 4.469853 4.012170
#> [10,] 4.505160 3.979209
#> [11,] 4.322108 4.037525
#> [12,] 4.601847 3.998479
#> [13,] 4.369908 4.187627
#> [14,] 4.387833 4.104970
#> [15,] 4.266160 4.253043
#> [16,] 4.439978 4.485294
#> CCGTACTAGATGTGTA-400.2.3 CCGTTCAGTCGGCTCA-400.2.3
#> [1,] 4.35500 4.541802
#> [2,] 4.31750 3.712631
#> [3,] 4.21625 4.098082
#> [4,] 4.08875 3.969236
#> [5,] 4.27875 4.746290
#> [6,] 3.97125 3.828809
#> [7,] 4.05625 4.613464
#> [8,] 4.72625 4.398842
#> [9,] 4.32500 4.609121
#> [10,] 4.09250 3.809989
#> [11,] 4.24875 3.931596
#> [12,] 4.49875 4.471227
#> [13,] 4.83625 4.200507
#> [14,] 4.02000 4.456750
#> [15,] 4.36625 4.180601
#> [16,] 4.66750 4.079262
#> CCTAAAGAGTACGCGA-400.2.3 CCTAAAGCAATCAGAA-400.2.3
#> [1,] 4.199420 4.419817
#> [2,] 4.246555 4.289439
#> [3,] 4.106599 4.181226
#> [4,] 3.939086 4.374185
#> [5,] 4.424220 4.494133
#> [6,] 4.231327 4.367666
#> [7,] 4.353154 4.378096
#> [8,] 4.831762 4.863103
#> [9,] 4.361856 4.985658
#> [10,] 4.319797 4.421121
#> [11,] 4.065265 4.332464
#> [12,] 4.274837 4.464146
#> [13,] 4.562001 4.212516
#> [14,] 4.146483 4.800522
#> [15,] 4.253082 4.157757
#> [16,] 4.436548 4.460235
#> CCTAAAGGTAAGTGTA-400.2.3 CCTAAAGGTTCCGTCT-400.2.3
#> [1,] 4.866457 4.263678
#> [2,] 3.772192 4.400791
#> [3,] 3.899450 4.285432
#> [4,] 4.190102 4.547132
#> [5,] 4.841320 4.750165
#> [6,] 4.114690 4.441661
#> [7,] 4.559309 4.789057
#> [8,] 4.513747 4.970995
#> [9,] 3.968578 4.549110
#> [10,] 3.846819 4.258405
#> [11,] 4.113904 4.371127
#> [12,] 3.939513 4.388926
#> [13,] 3.950511 4.098220
#> [14,] 3.967793 4.188530
#> [15,] 4.042419 4.176664
#> [16,] 4.445405 4.315755
#> CCTACACCACATTAGC-400.2.3 CCTACACGTTAAAGAC-400.2.3
#> [1,] 4.499736 4.577889
#> [2,] 3.710735 4.214070
#> [3,] 4.051296 4.258291
#> [4,] 4.038604 4.056281
#> [5,] 4.931782 4.594975
#> [6,] 4.043892 4.330653
#> [7,] 4.766790 4.417085
#> [8,] 4.353252 4.884422
#> [9,] 4.134320 4.456281
#> [10,] 3.697515 4.251256
#> [11,] 4.391856 4.601005
#> [12,] 4.152300 4.408040
#> [13,] 4.125859 4.318593
#> [14,] 4.174511 4.040201
#> [15,] 3.881015 4.299497
#> [16,] 4.243258 4.391960
#> CCTACACGTTCGCTAA-400.2.3 CCTACCAAGTCGTTTG-400.2.3
#> [1,] 4.592689 4.468332
#> [2,] 3.582245 4.089206
#> [3,] 4.154047 4.320250
#> [4,] 4.236728 4.127565
#> [5,] 4.990426 4.719893
#> [6,] 3.910357 4.260482
#> [7,] 4.704091 3.868867
#> [8,] 4.523934 4.840321
#> [9,] 4.462141 4.460303
#> [10,] 3.942559 4.198930
#> [11,] 3.666667 4.042819
#> [12,] 4.130548 4.448707
#> [13,] 4.542211 4.603925
#> [14,] 4.345518 3.975022
#> [15,] 3.873803 4.076717
#> [16,] 4.238468 4.705620
#> CCTACCATCACCCGAG-400.2.3 CCTAGCTCACAGGCCT-400.2.3
#> [1,] 4.565415 4.311679
#> [2,] 3.827076 4.377332
#> [3,] 4.182025 4.019350
#> [4,] 4.061433 3.960608
#> [5,] 4.506257 4.605390
#> [6,] 4.257110 4.276434
#> [7,] 4.480091 4.275052
#> [8,] 4.259386 4.676572
#> [9,] 4.351536 4.779544
#> [10,] 4.153584 4.458880
#> [11,] 4.433447 4.651002
#> [12,] 4.276451 4.276434
#> [13,] 4.103527 4.444368
#> [14,] 4.323094 4.467173
#> [15,] 4.007964 4.213545
#> [16,] 4.046644 4.343469
#> CCTAGCTCATCATCCC-400.2.3 CCTATTATCACTTCAT-400.2.3
#> [1,] 4.286425 4.678161
#> [2,] 4.057569 4.324138
#> [3,] 4.511016 4.057471
#> [4,] 4.220327 4.341379
#> [5,] 4.403696 4.525287
#> [6,] 4.085288 4.218391
#> [7,] 4.502488 4.490805
#> [8,] 4.675195 4.858621
#> [9,] 4.069652 4.712644
#> [10,] 4.172708 4.350575
#> [11,] 4.364606 4.185057
#> [12,] 4.269367 4.420690
#> [13,] 4.051883 4.702299
#> [14,] 4.138593 4.425287
#> [15,] 4.215352 4.385057
#> [16,] 4.380242 4.625287
#> CCTATTATCAGTTCGA-400.2.3 CCTTACGAGGGAACGG-400.2.3
#> [1,] 4.190086 4.185265
#> [2,] 4.165075 4.347639
#> [3,] 4.349704 4.243205
#> [4,] 4.337881 4.111588
#> [5,] 4.753524 4.937768
#> [6,] 3.961346 4.317597
#> [7,] 4.464302 4.405579
#> [8,] 4.591633 4.788984
#> [9,] 4.222829 4.356223
#> [10,] 4.258754 4.089413
#> [11,] 4.156889 4.356223
#> [12,] 4.304229 4.422747
#> [13,] 4.322874 3.947067
#> [14,] 4.273306 4.035050
#> [15,] 4.123693 4.198140
#> [16,] 4.459754 4.573677
#> CCTTACGGTCTAGAGG-400.2.3 CCTTACGTCTTGGGTA-400.2.3
#> [1,] 4.952005 4.398940
#> [2,] 3.988989 4.217260
#> [3,] 4.460757 4.617714
#> [4,] 4.634952 4.124905
#> [5,] 4.463015 4.442846
#> [6,] 4.111801 4.776684
#> [7,] 4.145398 4.467827
#> [8,] 4.558442 4.738077
#> [9,] 4.165443 4.671461
#> [10,] 4.144551 4.482210
#> [11,] 4.081592 4.521575
#> [12,] 4.339356 4.346707
#> [13,] 4.272445 4.022710
#> [14,] 4.209486 4.402725
#> [15,] 4.215133 4.103709
#> [16,] 4.315641 4.216503
#> CCTTCCCAGCGCCTTG-400.2.3 CCTTCGAAGCGTGAAC-400.2.3
#> [1,] 4.212752 4.059394
#> [2,] 3.843852 4.181818
#> [3,] 4.035133 4.214545
#> [4,] 4.145738 4.350303
#> [5,] 4.462589 4.494545
#> [6,] 3.906962 4.273939
#> [7,] 4.945348 4.446061
#> [8,] 4.541965 4.601212
#> [9,] 3.987638 3.985455
#> [10,] 3.789200 4.386667
#> [11,] 4.043591 4.236364
#> [12,] 3.989590 4.080000
#> [13,] 4.240078 4.418182
#> [14,] 4.167209 4.084848
#> [15,] 3.938842 4.002424
#> [16,] 4.391672 4.701818
#> CGAATGTAGCCGATTT-400.2.3 CGAATGTCACTGAAGG-400.2.3
#> [1,] 4.664 4.298577
#> [2,] 4.104 4.221900
#> [3,] 3.967 3.988092
#> [4,] 3.851 4.234970
#> [5,] 4.714 5.060703
#> [6,] 4.301 4.040372
#> [7,] 4.162 4.549521
#> [8,] 4.971 4.454255
#> [9,] 4.587 4.054023
#> [10,] 4.164 3.952077
#> [11,] 4.311 4.284635
#> [12,] 4.386 3.882370
#> [13,] 4.617 4.097299
#> [14,] 4.027 4.462678
#> [15,] 4.092 4.024688
#> [16,] 4.538 4.221900
#> CGACCTTCAGTAGAGC-400.2.3 CGACCTTGTAGCTGCC-400.2.3
#> [1,] 4.549339 4.202787
#> [2,] 4.056968 4.731707
#> [3,] 4.016277 3.898955
#> [4,] 3.808749 4.028571
#> [5,] 4.565615 4.651568
#> [6,] 3.981689 3.792334
#> [7,] 4.522889 4.142857
#> [8,] 4.573754 5.109408
#> [9,] 4.077314 4.301045
#> [10,] 4.103764 3.938676
#> [11,] 3.771109 4.558188
#> [12,] 4.049847 4.183972
#> [13,] 4.412004 4.290592
#> [14,] 3.989827 4.643206
#> [15,] 4.151577 4.039721
#> [16,] 4.158698 4.413937
#> CGACTTCCACGGATAG-400.2.3 CGAGAAGAGGTTACCT-400.2.3
#> [1,] 4.453532 4.488536
#> [2,] 3.939777 3.465608
#> [3,] 4.001487 3.887713
#> [4,] 4.140520 4.088771
#> [5,] 4.692937 5.417989
#> [6,] 4.098885 3.839506
#> [7,] 4.562825 5.124045
#> [8,] 4.315985 4.245738
#> [9,] 4.406691 4.172840
#> [10,] 4.189591 3.601999
#> [11,] 4.247584 3.958848
#> [12,] 4.285502 3.776014
#> [13,] 3.985130 3.957084
#> [14,] 4.576208 4.682540
#> [15,] 4.126394 3.635509
#> [16,] 4.275093 3.895944
#> CGAGAAGGTACGCTGC-400.2.3 CGAGCCATCCAACCAA-400.2.3
#> [1,] 4.330552 4.261745
#> [2,] 4.142490 4.281879
#> [3,] 4.265725 4.065197
#> [4,] 4.233633 4.216683
#> [5,] 4.521181 4.559923
#> [6,] 4.504493 4.411314
#> [7,] 4.222721 4.470757
#> [8,] 5.054557 4.895494
#> [9,] 4.556483 4.126558
#> [10,] 4.302953 4.431448
#> [11,] 4.342105 4.394056
#> [12,] 4.360077 4.355705
#> [13,] 4.358151 4.443912
#> [14,] 4.392811 4.050815
#> [15,] 4.260591 4.092042
#> [16,] 4.685494 4.482263
#> CGATCGGCATCCCACT-400.2.3 CGATCGGTCAATCTCT-400.2.3
#> [1,] 4.144561 4.360321
#> [2,] 3.749910 4.398640
#> [3,] 4.176364 4.270087
#> [4,] 4.070473 4.317058
#> [5,] 5.323816 4.610012
#> [6,] 4.096133 4.542645
#> [7,] 5.152150 4.459209
#> [8,] 4.365378 4.991965
#> [9,] 4.118901 4.701483
#> [10,] 3.875678 4.438195
#> [11,] 4.034333 4.375155
#> [12,] 3.993495 4.721879
#> [13,] 4.207445 3.855377
#> [14,] 4.310083 4.477132
#> [15,] 3.993856 4.289246
#> [16,] 4.032526 4.392460
#> CGATCGGTCACCGTAA-400.2.3 CGATCGGTCATGCTCC-400.2.3
#> [1,] 4.209517 4.191231
#> [2,] 4.213354 4.356343
#> [3,] 4.297774 4.015858
#> [4,] 4.090560 4.149254
#> [5,] 4.542594 4.754664
#> [6,] 4.492709 3.805037
#> [7,] 4.550269 4.110075
#> [8,] 5.058327 4.434701
#> [9,] 4.599386 4.251866
#> [10,] 4.293937 4.463619
#> [11,] 4.371450 4.342351
#> [12,] 4.663853 4.585821
#> [13,] 4.120491 4.429104
#> [14,] 4.197237 4.130597
#> [15,] 3.937068 4.390858
#> [16,] 4.301612 4.396455
#> CGATGGCGTCCAGTAT-400.2.3 CGATGTACACATGACT-400.2.3
#> [1,] 4.337963 4.655827
#> [2,] 4.152778 4.338753
#> [3,] 4.181713 4.085366
#> [4,] 4.434028 4.227642
#> [5,] 4.476852 4.701897
#> [6,] 4.050926 4.612466
#> [7,] 4.487269 4.407859
#> [8,] 4.537037 5.017615
#> [9,] 4.196759 4.830623
#> [10,] 4.069444 4.028455
#> [11,] 4.140046 4.375339
#> [12,] 4.307870 4.551491
#> [13,] 4.190972 4.369919
#> [14,] 3.943287 4.688347
#> [15,] 4.057870 4.401084
#> [16,] 4.621528 4.574526
#> CGATTGAAGAGTACAT-400.2.3 CGCCAAGAGGCCCGTT-400.2.3
#> [1,] 4.540752 4.390633
#> [2,] 4.173197 3.886045
#> [3,] 4.456113 4.221149
#> [4,] 4.277429 4.168035
#> [5,] 4.568966 5.036697
#> [6,] 4.278213 3.891840
#> [7,] 4.145768 5.057460
#> [8,] 5.111285 4.366007
#> [9,] 4.747649 4.033800
#> [10,] 4.339342 4.009174
#> [11,] 4.250000 4.183969
#> [12,] 4.590125 4.132303
#> [13,] 4.645768 4.163689
#> [14,] 4.213166 4.248189
#> [15,] 4.100313 3.871560
#> [16,] 4.343260 4.068566
#> CGCGGTAAGAGAACAG-400.2.3 CGCGGTATCTGACCTC-400.2.3
#> [1,] 4.792835 4.393628
#> [2,] 3.440031 4.063720
#> [3,] 3.706386 4.192189
#> [4,] 3.901869 4.262076
#> [5,] 5.150312 4.738952
#> [6,] 3.777259 3.971223
#> [7,] 5.051402 4.570401
#> [8,] 4.211059 4.334018
#> [9,] 4.309969 4.066804
#> [10,] 3.542056 3.943474
#> [11,] 4.035047 3.982528
#> [12,] 4.099688 4.155190
#> [13,] 4.254673 4.035971
#> [14,] 4.388629 4.226105
#> [15,] 3.979751 3.977390
#> [16,] 4.311526 4.086331
#> CGCGGTATCTTCCTTC-400.2.3 CGCGTTTAGGATGCGT-400.2.3
#> [1,] 5.034713 4.801083
#> [2,] 3.680908 4.294993
#> [3,] 4.166889 4.280108
#> [4,] 4.510681 4.424899
#> [5,] 4.763685 4.358593
#> [6,] 4.094126 4.784844
#> [7,] 4.841121 4.059540
#> [8,] 4.240988 5.108254
#> [9,] 3.866489 4.845737
#> [10,] 4.006676 4.201624
#> [11,] 4.345127 4.017591
#> [12,] 4.009346 4.667118
#> [13,] 4.079439 4.387009
#> [14,] 3.982644 4.418133
#> [15,] 3.885180 3.982409
#> [16,] 3.870494 4.470907
#> CGCGTTTGTCAATGTC-400.2.3 CGCTGGATCCTACAGA-400.2.3
#> [1,] 4.392985 4.168116
#> [2,] 3.963949 4.309179
#> [3,] 4.172459 4.091787
#> [4,] 4.248457 4.066667
#> [5,] 4.949009 4.585507
#> [6,] 4.201039 4.313043
#> [7,] 4.688210 4.016425
#> [8,] 4.633323 4.447343
#> [9,] 4.202014 4.404831
#> [10,] 3.949334 4.618357
#> [11,] 4.239039 4.040580
#> [12,] 4.165963 4.329469
#> [13,] 4.251380 4.443478
#> [14,] 4.185450 4.132367
#> [15,] 4.197791 4.295652
#> [16,] 4.433907 4.652174
#> CGCTTCAAGTTAGGTA-400.2.3 CGCTTCATCTAGAGTC-400.2.3
#> [1,] 4.154217 4.640362
#> [2,] 4.428916 4.671410
#> [3,] 4.119277 3.877102
#> [4,] 4.212048 3.932730
#> [5,] 4.503614 4.404916
#> [6,] 4.167470 4.573092
#> [7,] 4.330120 4.503234
#> [8,] 4.971084 4.671410
#> [9,] 4.226506 4.384217
#> [10,] 4.268675 5.064683
#> [11,] 4.095181 4.181113
#> [12,] 4.414458 4.311772
#> [13,] 4.267470 4.236740
#> [14,] 4.019277 4.134541
#> [15,] 4.226506 4.036223
#> [16,] 4.561446 4.131953
#> CGGACACAGGAATCGC-400.2.3 CGGACACAGGGAAACA-400.2.3
#> [1,] 4.328895 4.501183
#> [2,] 4.282290 4.353526
#> [3,] 4.095206 4.329863
#> [4,] 3.820905 4.340274
#> [5,] 4.825566 4.664931
#> [6,] 4.033955 4.679129
#> [7,] 4.380826 4.743019
#> [8,] 4.458722 4.669664
#> [9,] 4.272969 4.600568
#> [10,] 3.768309 4.464742
#> [11,] 4.023968 4.437293
#> [12,] 4.079893 4.313299
#> [13,] 4.555260 4.318031
#> [14,] 4.304927 4.092759
#> [15,] 3.998668 4.088027
#> [16,] 4.832224 4.689068
#> CGGACACTCTGCAAGT-400.2.3 CGGACGTGTCTCCCTA-400.2.3
#> [1,] 4.369285 4.394924
#> [2,] 4.044549 3.852792
#> [3,] 4.589683 4.157360
#> [4,] 4.001172 4.243655
#> [5,] 4.652989 4.461929
#> [6,] 4.078546 4.028426
#> [7,] 4.069168 4.411168
#> [8,] 5.128957 4.497462
#> [9,] 4.399766 4.660914
#> [10,] 4.491208 4.340102
#> [11,] 4.498242 3.897462
#> [12,] 4.664713 4.416244
#> [13,] 4.385698 4.220305
#> [14,] 3.902696 4.301523
#> [15,] 4.130129 3.983756
#> [16,] 4.685815 4.204061
#> CGGAGCTGTAATAGCA-400.2.3 CGGAGTCCACAAGTAA-400.2.3
#> [1,] 4.674847 4.400419
#> [2,] 4.315951 4.207547
#> [3,] 4.329243 4.054507
#> [4,] 4.452965 4.390985
#> [5,] 4.553170 4.382600
#> [6,] 4.304703 4.627883
#> [7,] 4.234151 4.171908
#> [8,] 5.124744 5.284067
#> [9,] 5.067485 5.092243
#> [10,] 4.213701 4.140461
#> [11,] 4.219836 4.439203
#> [12,] 4.646217 4.460168
#> [13,] 4.525562 4.290356
#> [14,] 4.547035 4.312369
#> [15,] 4.028630 4.063941
#> [16,] 4.303681 4.476939
#> CGGAGTCTCATGCATG-400.2.3 CGGGTCAAGATAGCAT-400.2.3
#> [1,] 4.469763 4.533898
#> [2,] 4.317266 4.182426
#> [3,] 4.375110 4.208296
#> [4,] 4.618755 4.012043
#> [5,] 4.200701 4.963872
#> [6,] 4.399649 4.067797
#> [7,] 4.276950 4.526762
#> [8,] 4.848379 4.531668
#> [9,] 5.285714 4.290812
#> [10,] 4.680105 4.144068
#> [11,] 4.410167 4.293042
#> [12,] 4.305872 4.174398
#> [13,] 4.070114 4.230598
#> [14,] 4.558282 4.426851
#> [15,] 4.281332 4.065120
#> [16,] 4.358457 4.419715
#> CGGGTCAAGGTGCTAG-400.2.3 CGGGTCAGTCATCCCT-400.2.3
#> [1,] 4.487594 4.460693
#> [2,] 3.713214 4.194421
#> [3,] 3.838430 4.417582
#> [4,] 3.915176 4.047337
#> [5,] 4.978650 4.483516
#> [6,] 4.037507 4.355875
#> [7,] 4.815349 4.400676
#> [8,] 4.275245 4.811496
#> [9,] 4.146567 4.563821
#> [10,] 3.873053 4.344886
#> [11,] 4.357184 4.306847
#> [12,] 4.092325 4.635672
#> [13,] 4.042701 4.561285
#> [14,] 4.336411 4.311919
#> [15,] 3.715522 3.908707
#> [16,] 4.160415 4.810651
#> CGGGTCAGTCGCTTTC-400.2.3 CGGTTAAAGGGCTTGA-400.2.3
#> [1,] 4.478558 4.198600
#> [2,] 3.868421 4.359580
#> [3,] 3.975634 4.223097
#> [4,] 3.957115 4.097988
#> [5,] 4.758285 4.783027
#> [6,] 4.065302 4.027997
#> [7,] 4.565302 4.268591
#> [8,] 4.705653 4.676290
#> [9,] 4.276803 4.307962
#> [10,] 3.815789 4.039370
#> [11,] 4.295322 4.236220
#> [12,] 3.846979 4.002625
#> [13,] 4.256335 4.543307
#> [14,] 4.047758 3.936133
#> [15,] 3.568226 4.308836
#> [16,] 4.385965 4.448819
#> CGGTTAACACGGCCAT-400.2.3 CGGTTAAGTGTTTGGT-400.2.3
#> [1,] 4.276810 4.535321
#> [2,] 4.248660 3.977317
#> [3,] 4.198391 3.863901
#> [4,] 4.228552 4.399870
#> [5,] 4.502011 5.022035
#> [6,] 4.148794 4.122489
#> [7,] 4.338472 4.327285
#> [8,] 4.310992 4.541154
#> [9,] 4.545576 4.136099
#> [10,] 3.948391 4.016850
#> [11,] 4.147453 3.939728
#> [12,] 4.205094 4.242385
#> [13,] 4.440349 4.305250
#> [14,] 4.368633 4.045366
#> [15,] 4.162198 4.078419
#> [16,] 4.143432 4.280622
#> CGTAGCGAGATGGCGT-400.2.3 CGTAGCGAGCTTTGGT-400.2.3
#> [1,] 4.378702 4.417819
#> [2,] 3.873007 4.185100
#> [3,] 4.070046 3.968510
#> [4,] 4.135535 4.150538
#> [5,] 5.082005 4.430108
#> [6,] 4.023918 4.136713
#> [7,] 4.982346 4.342550
#> [8,] 4.506264 4.599078
#> [9,] 3.906036 4.157450
#> [10,] 3.794989 3.954685
#> [11,] 4.044989 3.837174
#> [12,] 3.999431 4.287250
#> [13,] 4.193052 4.254224
#> [14,] 4.245444 4.254224
#> [15,] 4.158314 4.179724
#> [16,] 4.299544 4.324885
#> CGTAGCGGTAGATTAG-400.2.3 CGTCACTAGTTTAGGA-400.2.3
#> [1,] 4.506180 4.253968
#> [2,] 3.929213 4.491402
#> [3,] 3.912360 4.356481
#> [4,] 4.218539 4.219577
#> [5,] 5.344382 4.742725
#> [6,] 3.925843 4.351190
#> [7,] 5.082584 4.349868
#> [8,] 4.269663 4.976852
#> [9,] 4.128652 4.506614
#> [10,] 3.936517 4.443122
#> [11,] 4.097753 4.249339
#> [12,] 4.144382 4.386243
#> [13,] 4.159551 4.399471
#> [14,] 4.318539 4.230159
#> [15,] 3.769101 4.220238
#> [16,] 3.884270 4.552249
#> CGTCTACCATTTCAGG-400.2.3 CGTGAGCAGGAGCGTT-400.2.3
#> [1,] 4.397559 4.488466
#> [2,] 4.124673 3.659170
#> [3,] 4.176112 3.839100
#> [4,] 4.251090 4.258362
#> [5,] 4.798605 4.894464
#> [6,] 4.107236 3.952134
#> [7,] 4.517001 4.892157
#> [8,] 4.803836 4.366205
#> [9,] 4.411508 4.258939
#> [10,] 4.335658 3.967705
#> [11,] 3.972973 3.712803
#> [12,] 4.229294 4.153403
#> [13,] 3.994769 4.367359
#> [14,] 3.840453 4.368512
#> [15,] 3.897995 4.014418
#> [16,] 4.401918 4.170127
#> CGTGAGCGTGTTGGGA-400.2.3 CGTGAGCTCACTTCAT-400.2.3
#> [1,] 4.269058 4.518097
#> [2,] 4.209865 4.558428
#> [3,] 4.371300 3.865564
#> [4,] 4.436771 4.373320
#> [5,] 4.153363 4.411582
#> [6,] 4.470852 4.186143
#> [7,] 4.500448 4.148914
#> [8,] 4.860987 4.523268
#> [9,] 4.570404 4.564633
#> [10,] 4.334529 4.097208
#> [11,] 4.284305 4.234747
#> [12,] 4.301345 4.476732
#> [13,] 4.556054 4.597725
#> [14,] 4.437668 4.095140
#> [15,] 4.356951 4.170631
#> [16,] 4.426906 5.057911
#> CGTGAGCTCTTAACCT-400.2.3 CGTGTAAAGGACATTA-400.2.3
#> [1,] 4.486518 4.674870
#> [2,] 3.941383 4.450777
#> [3,] 4.162954 4.512953
#> [4,] 4.220399 4.151554
#> [5,] 4.868699 4.690415
#> [6,] 3.697538 4.506477
#> [7,] 4.500586 4.275907
#> [8,] 4.753810 5.049223
#> [9,] 4.402110 4.674870
#> [10,] 4.188746 4.098446
#> [11,] 4.031653 4.349741
#> [12,] 4.141852 4.408031
#> [13,] 4.633060 4.553109
#> [14,] 4.266120 4.322539
#> [15,] 4.208675 3.927461
#> [16,] 4.133646 4.483161
#> CGTGTCTAGGTACTCT-400.2.3 CGTTAGAAGGCTAGCA-400.2.3
#> [1,] 4.347410 4.657431
#> [2,] 4.211155 4.429471
#> [3,] 4.333068 4.303526
#> [4,] 4.419124 3.807305
#> [5,] 4.843825 4.906801
#> [6,] 3.966534 4.176322
#> [7,] 4.215936 4.037783
#> [8,] 4.733068 4.835013
#> [9,] 4.338645 4.625945
#> [10,] 4.036653 4.044081
#> [11,] 4.635060 4.001259
#> [12,] 4.230279 4.372796
#> [13,] 4.407171 4.443325
#> [14,] 4.192032 3.886650
#> [15,] 3.998406 4.273300
#> [16,] 4.223108 4.513854
#> CGTTAGACAGCTTCGG-400.2.3 CGTTAGAGTCGCATAT-400.2.3
#> [1,] 4.973226 4.410165
#> [2,] 3.650602 3.909091
#> [3,] 3.611780 4.065855
#> [4,] 4.433066 3.982820
#> [5,] 5.172691 5.050107
#> [6,] 4.012048 4.027917
#> [7,] 4.546854 4.994273
#> [8,] 4.386212 4.256263
#> [9,] 4.188086 3.923407
#> [10,] 3.755020 3.847530
#> [11,] 3.723561 3.851110
#> [12,] 3.837349 4.165354
#> [13,] 4.397590 4.227631
#> [14,] 4.287149 4.204009
#> [15,] 3.663320 4.160344
#> [16,] 3.870147 4.404438
#> CGTTCTGGTAGCTCCG-400.2.3 CGTTCTGGTTAAGACA-400.2.3
#> [1,] 4.406388 4.538509
#> [2,] 4.655286 3.734161
#> [3,] 4.064978 4.093168
#> [4,] 4.089207 4.237267
#> [5,] 4.541850 4.821739
#> [6,] 4.581498 4.222360
#> [7,] 4.544053 4.630435
#> [8,] 4.933921 4.363354
#> [9,] 4.297357 4.416770
#> [10,] 4.762115 3.982609
#> [11,] 4.504405 4.319876
#> [12,] 4.232379 4.229814
#> [13,] 4.533040 4.307453
#> [14,] 4.094714 4.128571
#> [15,] 4.039648 3.718012
#> [16,] 4.263216 4.091304
#> CGTTGGGAGATAGGAG-400.2.3 CTAACTTCATCGGTTA-400.2.3
#> [1,] 4.312500 4.366820
#> [2,] 4.096301 4.073781
#> [3,] 4.073980 4.268862
#> [4,] 4.387755 4.150479
#> [5,] 4.645408 4.994581
#> [6,] 3.962372 4.004168
#> [7,] 4.540816 4.540225
#> [8,] 4.378189 4.354314
#> [9,] 4.149872 4.127970
#> [10,] 3.945791 3.836182
#> [11,] 3.926020 4.068779
#> [12,] 4.309949 4.350146
#> [13,] 4.191964 4.254689
#> [14,] 4.274872 4.271363
#> [15,] 4.205995 4.278866
#> [16,] 4.248087 4.274698
#> CTAACTTTCTGCTGTC-400.2.3 CTACACCAGCCCAATT-400.2.3
#> [1,] 4.466731 4.225131
#> [2,] 4.635336 4.208377
#> [3,] 4.893411 4.126702
#> [4,] 4.404070 3.810471
#> [5,] 4.363695 4.742408
#> [6,] 4.347222 4.148691
#> [7,] 4.584302 4.263874
#> [8,] 4.371124 4.530890
#> [9,] 4.392119 4.281675
#> [10,] 4.576227 4.247120
#> [11,] 4.464147 4.429319
#> [12,] 4.330426 4.392670
#> [13,] 4.173773 4.321466
#> [14,] 4.413760 4.076440
#> [15,] 4.254199 4.091099
#> [16,] 4.474160 4.624084
#> CTACACCCAGTCACTA-400.2.3 CTACACCTCAAGGTAA-400.2.3
#> [1,] 4.528588 4.510181
#> [2,] 4.077013 4.084842
#> [3,] 3.732789 4.038462
#> [4,] 4.183197 4.453620
#> [5,] 4.397900 4.197964
#> [6,] 4.835473 3.841629
#> [7,] 4.644107 4.290724
#> [8,] 5.075846 4.520362
#> [9,] 4.652275 4.204751
#> [10,] 4.070012 3.996606
#> [11,] 4.147025 4.115385
#> [12,] 4.499417 4.290724
#> [13,] 4.575263 4.781674
#> [14,] 4.383897 4.056561
#> [15,] 4.046674 3.970588
#> [16,] 4.532089 4.324661
#> CTACATTTCAGTGCAT-400.2.3 CTACCCACACCGGAAA-400.2.3
#> [1,] 4.492711 4.125844
#> [2,] 3.847425 4.278085
#> [3,] 4.213800 4.375077
#> [4,] 4.366375 4.106814
#> [5,] 4.456754 4.509515
#> [6,] 3.807580 4.207489
#> [7,] 4.434402 4.435236
#> [8,] 4.736638 4.836096
#> [9,] 4.286686 4.240638
#> [10,] 4.120505 4.165132
#> [11,] 4.018465 4.271946
#> [12,] 4.305151 4.073051
#> [13,] 4.379009 4.305095
#> [14,] 4.099125 3.904850
#> [15,] 3.987366 4.098220
#> [16,] 4.681244 4.128300
#> CTACCCATCAGTACGT-400.2.3 CTACCCATCCGGGTGT-400.2.3
#> [1,] 5.125697 4.561629
#> [2,] 3.416624 4.014469
#> [3,] 3.806386 3.969989
#> [4,] 4.727826 4.327974
#> [5,] 4.865180 5.222401
#> [6,] 3.974658 4.021436
#> [7,] 4.351749 4.520364
#> [8,] 4.403447 4.363344
#> [9,] 4.354790 4.018221
#> [10,] 3.562595 3.926581
#> [11,] 3.673594 4.100750
#> [12,] 4.000507 3.862272
#> [13,] 4.350735 4.228832
#> [14,] 4.165231 4.126474
#> [15,] 3.725798 4.270096
#> [16,] 3.891029 4.798499
#> CTACGTCAGGGTTCCC-400.2.3 CTACGTCTCGATCCCT-400.2.3
#> [1,] 4.387566 4.232119
#> [2,] 3.560847 4.109312
#> [3,] 3.854497 4.213900
#> [4,] 4.293651 4.284076
#> [5,] 5.150794 4.732119
#> [6,] 3.883598 3.791498
#> [7,] 4.638889 4.518893
#> [8,] 4.218254 4.452767
#> [9,] 3.927249 4.389339
#> [10,] 3.974868 4.131579
#> [11,] 4.007937 4.309042
#> [12,] 3.853175 4.269231
#> [13,] 4.157407 4.397436
#> [14,] 4.166667 4.578273
#> [15,] 3.798942 3.823887
#> [16,] 4.166667 4.103914
#> CTCAGAAGTCTTCAAG-400.2.3 CTCCTAGGTCCGAGTC-400.2.3
#> [1,] 4.557029 4.437225
#> [2,] 4.708223 4.968062
#> [3,] 4.551724 4.099119
#> [4,] 4.282493 3.796256
#> [5,] 5.156499 4.925110
#> [6,] 3.809019 4.154185
#> [7,] 4.299735 4.047357
#> [8,] 4.640584 5.006608
#> [9,] 4.140584 4.415198
#> [10,] 4.080902 4.259912
#> [11,] 4.127321 4.339207
#> [12,] 4.173740 4.081498
#> [13,] 4.303714 4.427313
#> [14,] 4.850133 4.323789
#> [15,] 3.718833 3.810573
#> [16,] 4.095491 4.463656
#> CTCGAAACATACGCCG-400.2.3 CTCGAGGTCGTCCGTT-400.2.3
#> [1,] 4.544839 4.583265
#> [2,] 4.450085 4.277276
#> [3,] 4.181049 4.189500
#> [4,] 4.286802 4.139459
#> [5,] 4.613367 4.410993
#> [6,] 4.492386 4.036095
#> [7,] 4.315567 4.147662
#> [8,] 4.978003 4.664479
#> [9,] 4.804569 4.467596
#> [10,] 4.198816 4.455291
#> [11,] 4.126058 3.979491
#> [12,] 4.432318 4.330599
#> [13,] 4.393401 4.595570
#> [14,] 4.239425 4.164889
#> [15,] 4.119289 4.205906
#> [16,] 4.274958 4.361772
#> CTCGAGGTCTGAGGGA-400.2.3 CTCGGAGAGTGGTAGC-400.2.3
#> [1,] 4.641469 4.399707
#> [2,] 4.411447 4.347731
#> [3,] 4.154428 4.316252
#> [4,] 4.184665 4.265739
#> [5,] 4.615551 4.861640
#> [6,] 4.348812 4.729868
#> [7,] 4.133909 4.361640
#> [8,] 4.793737 5.137628
#> [9,] 4.361771 4.808931
#> [10,] 4.154428 4.065154
#> [11,] 4.251620 4.458272
#> [12,] 4.181425 4.376281
#> [13,] 4.507559 4.176428
#> [14,] 4.128510 4.105417
#> [15,] 4.077754 4.057833
#> [16,] 4.363931 4.676428
#> CTCGGAGGTCCCGACA-400.2.3 CTCGGAGGTCGTTGTA-400.2.3
#> [1,] 4.785714 4.457342
#> [2,] 3.902423 3.790676
#> [3,] 4.369898 4.291786
#> [4,] 4.392219 4.200761
#> [5,] 5.168367 4.921345
#> [6,] 4.271684 4.072946
#> [7,] 5.080995 4.717729
#> [8,] 4.109694 4.276879
#> [9,] 4.316327 4.045354
#> [10,] 3.757015 3.917539
#> [11,] 4.435587 4.193784
#> [12,] 4.353316 4.140501
#> [13,] 4.322704 4.133524
#> [14,] 4.262755 4.157945
#> [15,] 3.758291 4.234380
#> [16,] 3.811862 4.232477
#> CTCGGAGGTGTCGCTG-400.2.3 CTCGTACGTGATGTCT-400.2.3
#> [1,] 3.893564 4.446941
#> [2,] 4.735149 4.198502
#> [3,] 4.065594 4.395755
#> [4,] 4.352723 4.353308
#> [5,] 4.543317 4.265918
#> [6,] 4.053218 4.257179
#> [7,] 4.519802 4.197253
#> [8,] 4.992574 4.735331
#> [9,] 4.424505 4.357054
#> [10,] 4.366337 4.161049
#> [11,] 4.592822 3.916355
#> [12,] 4.092822 4.355805
#> [13,] 4.282178 4.350811
#> [14,] 4.591584 4.063670
#> [15,] 3.837871 4.248439
#> [16,] 4.455446 4.887640
#> CTCGTACTCCACGCAG-400.2.3 CTCGTCACAGCCTTTC-400.2.3
#> [1,] 4.705255 4.397260
#> [2,] 3.897373 4.488584
#> [3,] 4.224959 4.420091
#> [4,] 4.293924 4.262557
#> [5,] 4.463054 4.503044
#> [6,] 4.056650 4.188737
#> [7,] 4.077176 4.432268
#> [8,] 4.694581 4.942922
#> [9,] 4.341544 4.460426
#> [10,] 3.956486 4.143836
#> [11,] 4.084565 4.096651
#> [12,] 4.057471 4.566971
#> [13,] 4.564860 4.479452
#> [14,] 4.064039 4.108828
#> [15,] 4.027915 4.058600
#> [16,] 4.689655 4.345510
#> CTCGTCAGTTCCACTC-400.2.3 CTCGTCATCAGATAAG-400.2.3
#> [1,] 4.552525 4.583686
#> [2,] 4.250505 4.138771
#> [3,] 4.298990 4.287076
#> [4,] 4.378788 4.313559
#> [5,] 4.322222 4.340042
#> [6,] 4.873737 4.147246
#> [7,] 4.288889 4.315678
#> [8,] 4.742424 5.043432
#> [9,] 4.605051 4.573093
#> [10,] 4.515152 4.370763
#> [11,] 4.429293 4.348517
#> [12,] 4.706061 4.743644
#> [13,] 4.252525 4.276483
#> [14,] 4.192929 4.158898
#> [15,] 4.408081 4.239407
#> [16,] 4.344444 4.340042
#> CTCGTCATCCTCTAGC-400.2.3 CTCTAATAGCTTATCG-400.2.3
#> [1,] 4.669417 4.238059
#> [2,] 3.457096 4.404094
#> [3,] 3.951595 4.366187
#> [4,] 4.089109 4.253222
#> [5,] 4.786579 4.563306
#> [6,] 3.970847 4.059136
#> [7,] 4.831133 4.133434
#> [8,] 4.295930 4.677786
#> [9,] 4.145765 4.388931
#> [10,] 3.756326 4.377559
#> [11,] 4.198020 4.191054
#> [12,] 4.045655 4.292646
#> [13,] 4.356986 4.434420
#> [14,] 4.151815 4.078848
#> [15,] 3.647965 4.178165
#> [16,] 3.698570 4.462472
#> CTCTAATCATCGTCGG-400.2.3 CTCTAATGTTCTCATT-400.2.3
#> [1,] 4.559105 4.412506
#> [2,] 4.125666 4.413011
#> [3,] 4.317359 4.162885
#> [4,] 4.355698 3.718608
#> [5,] 4.336528 4.351992
#> [6,] 4.511182 4.218356
#> [7,] 4.499468 3.935451
#> [8,] 4.973376 4.708018
#> [9,] 4.495208 4.640948
#> [10,] 4.435570 4.080182
#> [11,] 4.412141 4.157337
#> [12,] 4.502662 4.315179
#> [13,] 4.307774 4.656077
#> [14,] 4.443024 4.236006
#> [15,] 4.256656 4.120524
#> [16,] 4.443024 4.618255
#> CTCTAATTCTCGAGTA-400.2.3 CTCTACGAGAGTAAGG-400.2.3
#> [1,] 4.520599 4.635910
#> [2,] 4.077403 3.793017
#> [3,] 4.313358 3.609310
#> [4,] 4.241573 3.695761
#> [5,] 4.834582 5.217789
#> [6,] 5.047441 3.906068
#> [7,] 4.357054 4.640898
#> [8,] 4.689139 4.137988
#> [9,] 4.541199 4.112219
#> [10,] 4.437578 3.648379
#> [11,] 4.918227 4.214464
#> [12,] 4.431336 4.028263
#> [13,] 3.995006 4.477972
#> [14,] 4.291511 4.428096
#> [15,] 4.239700 3.950956
#> [16,] 4.529338 4.640898
#> CTCTACGAGCGTTTAC-400.2.3 CTCTGGTAGCTAACAA-400.2.3
#> [1,] 4.786179 4.605485
#> [2,] 4.055285 3.774262
#> [3,] 4.017886 4.161041
#> [4,] 4.271545 4.161744
#> [5,] 4.814634 5.517581
#> [6,] 4.070732 4.018284
#> [7,] 4.169106 5.106892
#> [8,] 4.559350 4.092827
#> [9,] 4.040650 3.973980
#> [10,] 4.193496 3.827707
#> [11,] 4.124390 3.643460
#> [12,] 4.204878 4.061885
#> [13,] 4.108130 4.086498
#> [14,] 4.378862 4.481716
#> [15,] 4.194309 3.594937
#> [16,] 4.515447 3.827707
#> CTCTGGTCATTAACCG-400.2.3 CTGATAGAGCGAGAAA-400.2.3
#> [1,] 4.275012 4.503432
#> [2,] 3.977240 4.053776
#> [3,] 4.183025 3.853547
#> [4,] 4.085349 4.494279
#> [5,] 4.806069 4.618993
#> [6,] 4.105263 4.411899
#> [7,] 4.886202 4.231121
#> [8,] 4.467520 4.835240
#> [9,] 4.360360 4.494279
#> [10,] 4.113798 4.405034
#> [11,] 4.524419 4.223112
#> [12,] 4.200569 4.251716
#> [13,] 3.965861 5.000000
#> [14,] 4.270270 4.279176
#> [15,] 3.567093 3.967963
#> [16,] 4.196302 4.360412
#> CTGATAGAGGCCGAAT-400.2.3 CTGATAGGTCAAAGCG-400.2.3
#> [1,] 4.336308 4.442024
#> [2,] 4.113996 3.745257
#> [3,] 4.074645 4.012298
#> [4,] 4.225558 4.370696
#> [5,] 4.971197 5.102952
#> [6,] 4.088438 3.927618
#> [7,] 5.020284 4.997892
#> [8,] 4.447465 4.397048
#> [9,] 4.029615 4.020379
#> [10,] 4.108722 4.033380
#> [11,] 4.009736 3.982783
#> [12,] 4.211359 3.974350
#> [13,] 4.154564 4.055517
#> [14,] 4.086004 4.236121
#> [15,] 4.255172 3.809206
#> [16,] 4.591075 4.122628
#> CTGATCCAGACCACGA-400.2.3 CTGATCCTCATCTGCC-400.2.3
#> [1,] 4.311370 4.405890
#> [2,] 4.233204 4.399488
#> [3,] 4.388889 4.076825
#> [4,] 4.119509 4.192061
#> [5,] 4.675065 4.235595
#> [6,] 4.120801 3.737516
#> [7,] 4.698320 4.271447
#> [8,] 4.841085 4.943662
#> [9,] 4.524548 4.489117
#> [10,] 4.398579 4.166453
#> [11,] 4.705426 4.143406
#> [12,] 4.760982 4.297055
#> [13,] 4.336563 4.699104
#> [14,] 4.013566 4.220230
#> [15,] 4.522610 4.353393
#> [16,] 4.709302 4.868118
#> CTGCCTAGTTTGTGTG-400.2.3 CTGCCTATCAGCTTAG-400.2.3
#> [1,] 4.329221 4.519597
#> [2,] 4.296104 4.406495
#> [3,] 4.326623 4.051512
#> [4,] 4.100000 3.992161
#> [5,] 4.617532 4.519597
#> [6,] 3.951948 4.547592
#> [7,] 4.214935 4.255319
#> [8,] 4.890909 4.581187
#> [9,] 4.256494 4.641657
#> [10,] 3.805195 4.078387
#> [11,] 4.404545 4.423292
#> [12,] 4.161039 4.302352
#> [13,] 4.174026 4.446809
#> [14,] 4.457792 4.083987
#> [15,] 4.045455 4.003359
#> [16,] 4.442857 4.790594
#> CTGCCTATCTTACCTA-400.2.3 CTGCTGTAGCACAGGT-400.2.3
#> [1,] 4.618274 4.459516
#> [2,] 4.113229 4.405889
#> [3,] 3.815022 4.527865
#> [4,] 4.010650 4.115668
#> [5,] 5.404709 4.553102
#> [6,] 3.859865 4.257624
#> [7,] 4.963565 4.280757
#> [8,] 4.455717 4.672976
#> [9,] 4.142937 4.521556
#> [10,] 3.469170 4.299685
#> [11,] 4.139013 3.874869
#> [12,] 3.761771 4.461619
#> [13,] 4.048206 4.493165
#> [14,] 4.755605 4.309148
#> [15,] 3.701794 4.187171
#> [16,] 4.466368 4.789695
#> CTGCTGTGTATATGAG-400.2.3 CTGTGCTAGTTCGCGC-400.2.3
#> [1,] 4.723041 4.178215
#> [2,] 3.698291 4.347066
#> [3,] 4.011196 3.901685
#> [4,] 4.183854 4.068040
#> [5,] 4.947555 4.879526
#> [6,] 3.991750 3.735643
#> [7,] 4.706541 4.567416
#> [8,] 4.593989 4.917291
#> [9,] 4.271656 3.974719
#> [10,] 3.967001 4.027154
#> [11,] 4.137890 4.413858
#> [12,] 3.901002 4.026529
#> [13,] 4.259281 3.995006
#> [14,] 4.165586 4.522472
#> [15,] 4.100766 3.859551
#> [16,] 4.373600 4.026841
#> CTGTGCTCATCGGACC-400.2.3 CTGTGCTTCCAAACTG-400.2.3
#> [1,] 4.209001 4.551862
#> [2,] 3.983982 3.650931
#> [3,] 4.080854 3.833777
#> [4,] 4.402746 3.960106
#> [5,] 4.649123 5.333777
#> [6,] 4.136537 3.846410
#> [7,] 4.453089 5.058511
#> [8,] 4.247902 4.180851
#> [9,] 4.314264 4.216755
#> [10,] 3.899314 3.672207
#> [11,] 4.198322 4.220080
#> [12,] 4.304348 3.871011
#> [13,] 4.189931 4.197473
#> [14,] 4.295957 4.363697
#> [15,] 4.025934 3.585106
#> [16,] 4.210526 4.087766
#> CTGTTTAAGATCTGCT-400.2.3 CTTAACTCAGCCTTGG-400.2.3
#> [1,] 4.417778 4.111732
#> [2,] 3.758889 3.812291
#> [3,] 4.228333 4.112849
#> [4,] 4.261111 4.413966
#> [5,] 4.606111 4.749162
#> [6,] 3.833333 3.883799
#> [7,] 4.453333 4.677654
#> [8,] 4.721111 4.468715
#> [9,] 4.099444 4.421788
#> [10,] 3.836667 4.058101
#> [11,] 3.899444 4.202793
#> [12,] 4.157222 3.976536
#> [13,] 4.318333 4.204469
#> [14,] 4.127222 4.294972
#> [15,] 4.540000 3.700559
#> [16,] 4.412778 4.341899
#> CTTAACTGTTGTTTGG-400.2.3 CTTACCGCAGACAAGC-400.2.3
#> [1,] 4.408611 4.324935
#> [2,] 3.970755 4.040052
#> [3,] 4.362307 4.238372
#> [4,] 3.945573 4.411499
#> [5,] 4.431357 4.454134
#> [6,] 3.898457 3.925711
#> [7,] 4.260764 4.527778
#> [8,] 4.501219 4.529070
#> [9,] 4.506905 4.211886
#> [10,] 4.202275 4.099483
#> [11,] 4.005686 4.422481
#> [12,] 4.456539 4.356589
#> [13,] 4.463851 4.214470
#> [14,] 3.834281 4.200258
#> [15,] 4.571893 4.111111
#> [16,] 4.616572 4.197028
#> CTTACCGTCGAGAACG-400.2.3 CTTAGGAGTTATGCGT-400.2.3
#> [1,] 4.369023 4.217620
#> [2,] 3.967775 4.256024
#> [3,] 4.496881 4.292169
#> [4,] 4.360707 4.144578
#> [5,] 4.525988 4.454819
#> [6,] 4.399168 4.651355
#> [7,] 4.254678 4.670181
#> [8,] 4.670478 4.920934
#> [9,] 4.345114 4.494729
#> [10,] 4.353430 4.283886
#> [11,] 4.088358 4.377259
#> [12,] 4.520790 4.526355
#> [13,] 3.923077 4.249247
#> [14,] 4.495842 4.030120
#> [15,] 4.293139 4.278614
#> [16,] 4.204782 4.434488
#> CTTAGGATCAGAAATG-400.2.3 CTTCTCTCAATCAGAA-400.2.3
#> [1,] 4.357700 4.525123
#> [2,] 4.248538 4.487685
#> [3,] 4.269006 4.095567
#> [4,] 4.544834 4.402956
#> [5,] 4.132554 4.851232
#> [6,] 4.452242 4.829557
#> [7,] 4.519493 4.428571
#> [8,] 4.816764 4.918227
#> [9,] 4.858674 4.650246
#> [10,] 4.670565 4.353695
#> [11,] 4.165692 4.178325
#> [12,] 4.444444 4.479803
#> [13,] 4.675439 4.507389
#> [14,] 3.831384 4.487685
#> [15,] 4.269981 4.077833
#> [16,] 4.474659 4.567488
#> CTTCTCTGTCATCGGC-400.2.3 CTTTGCGAGAGTACCG-400.2.3
#> [1,] 4.056332 4.320051
#> [2,] 3.927997 3.897172
#> [3,] 4.078780 4.017995
#> [4,] 4.222787 4.520566
#> [5,] 5.283778 4.907455
#> [6,] 3.810250 4.683805
#> [7,] 5.110546 4.348329
#> [8,] 4.507412 5.277635
#> [9,] 4.082169 5.065553
#> [10,] 3.857687 4.048843
#> [11,] 4.095722 4.547558
#> [12,] 4.091487 4.718509
#> [13,] 4.155443 4.677378
#> [14,] 4.455739 3.740360
#> [15,] 3.714528 3.976864
#> [16,] 3.961881 4.203085
#> CTTTGCGTCTGTCAAG-400.2.3 GAAACTCAGTGTACTC-400.2.3
#> [1,] 4.386852 4.408813
#> [2,] 4.208597 3.929621
#> [3,] 4.178255 4.167687
#> [4,] 3.987358 4.266524
#> [5,] 4.587863 5.063035
#> [6,] 4.103666 4.025092
#> [7,] 4.403287 4.483476
#> [8,] 4.916561 4.585985
#> [9,] 4.879899 4.027846
#> [10,] 4.163085 3.925337
#> [11,] 3.996207 4.014076
#> [12,] 4.295828 4.134945
#> [13,] 4.591656 4.298348
#> [14,] 3.949431 4.182069
#> [15,] 3.960809 4.022032
#> [16,] 4.758534 4.319461
#> GAAACTCTCGAGCCCA-400.2.3 GAACATCAGATAGGAG-400.2.3
#> [1,] 4.363636 3.994856
#> [2,] 3.959684 4.656379
#> [3,] 3.916206 4.465021
#> [4,] 4.122530 4.085391
#> [5,] 5.014229 4.203704
#> [6,] 4.125692 4.119342
#> [7,] 4.742292 4.195473
#> [8,] 4.252174 5.386831
#> [9,] 4.149407 4.326132
#> [10,] 4.003162 4.135802
#> [11,] 4.218972 4.359053
#> [12,] 3.861660 3.936214
#> [13,] 4.342292 3.748971
#> [14,] 4.537549 4.448560
#> [15,] 3.909091 4.081276
#> [16,] 4.019763 4.618313
#> GAACATCGTTACGGAG-400.2.3 GAACCTATCGTCCAGG-400.2.3
#> [1,] 4.454315 4.625000
#> [2,] 4.126178 4.376359
#> [3,] 4.098985 3.788043
#> [4,] 4.078318 4.331522
#> [5,] 4.996737 4.769022
#> [6,] 4.044960 4.313859
#> [7,] 4.814358 3.993207
#> [8,] 4.443437 5.095109
#> [9,] 4.276287 4.932065
#> [10,] 4.027556 4.486413
#> [11,] 4.378535 4.091033
#> [12,] 4.283539 4.302989
#> [13,] 4.219724 4.866848
#> [14,] 4.484772 4.138587
#> [15,] 3.982234 4.165761
#> [16,] 4.363669 4.743207
#> GAACGGACACGAAGCA-400.2.3 GAACGGAGTTGAGTTC-400.2.3
#> [1,] 4.996785 4.431491
#> [2,] 3.689711 4.287661
#> [3,] 3.963023 4.277063
#> [4,] 3.997588 4.259652
#> [5,] 5.569132 4.623770
#> [6,] 3.820740 3.947010
#> [7,] 4.372990 4.091597
#> [8,] 4.060289 4.852385
#> [9,] 3.941318 4.167298
#> [10,] 3.788585 4.170326
#> [11,] 4.356913 4.154428
#> [12,] 3.928457 3.935655
#> [13,] 4.056270 4.241484
#> [14,] 4.614148 4.236942
#> [15,] 4.207395 3.934898
#> [16,] 4.959807 4.221045
#> GAATAAGAGGATGGAA-400.2.3 GAATGAATCACTTCAT-400.2.3
#> [1,] 4.476752 4.252407
#> [2,] 4.335878 3.934701
#> [3,] 4.228314 4.348681
#> [4,] 4.288688 4.405190
#> [5,] 4.836225 4.672248
#> [6,] 4.345593 3.901214
#> [7,] 4.551700 4.482210
#> [8,] 4.664816 4.517371
#> [9,] 4.489244 4.176224
#> [10,] 4.316447 4.101716
#> [11,] 4.129077 4.144830
#> [12,] 4.537821 4.259523
#> [13,] 4.312283 4.209293
#> [14,] 4.153366 4.310172
#> [15,] 4.129077 4.028045
#> [16,] 4.500347 4.114692
#> GACACGCAGAACTGTA-400.2.3 GACACGCCACGAAATA-400.2.3
#> [1,] 4.447102 4.830329
#> [2,] 4.476541 3.599751
#> [3,] 3.914443 4.050342
#> [4,] 4.192272 4.231821
#> [5,] 4.476541 5.250466
#> [6,] 4.599816 3.981355
#> [7,] 4.250230 4.635799
#> [8,] 4.838086 4.515848
#> [9,] 4.592456 4.014916
#> [10,] 4.343146 3.817899
#> [11,] 4.511500 4.287135
#> [12,] 4.406624 4.038533
#> [13,] 4.543698 4.178993
#> [14,] 3.850046 4.212554
#> [15,] 4.135235 4.004972
#> [16,] 4.334867 3.942200
#> GACACGCGTAGCGCAA-400.2.3 GACCAATAGGCTCAGA-400.2.3
#> [1,] 4.498616 4.324374
#> [2,] 3.919203 3.621258
#> [3,] 4.049806 4.304215
#> [4,] 4.182623 4.086744
#> [5,] 4.843940 5.083079
#> [6,] 4.274488 3.626145
#> [7,] 4.668511 5.140501
#> [8,] 4.451024 4.385461
#> [9,] 4.131157 4.141112
#> [10,] 4.056447 3.738546
#> [11,] 3.965136 4.411729
#> [12,] 4.021029 4.321319
#> [13,] 4.353625 4.104459
#> [14,] 4.412839 4.079414
#> [15,] 4.035418 4.079414
#> [16,] 4.070836 4.571167
#> GACCAATGTTCATGGT-400.2.3 GACCAATTCCCTCTTT-400.2.3
#> [1,] 4.297691 4.317682
#> [2,] 4.195626 3.878210
#> [3,] 4.227217 3.994864
#> [4,] 4.461725 4.247982
#> [5,] 4.631835 5.249450
#> [6,] 4.504253 3.645635
#> [7,] 4.144593 4.617021
#> [8,] 4.736330 4.409391
#> [9,] 4.370595 4.291269
#> [10,] 4.076549 3.733676
#> [11,] 4.174970 3.944974
#> [12,] 4.524909 3.894351
#> [13,] 4.705954 4.520176
#> [14,] 4.601458 4.237711
#> [15,] 4.340219 3.892150
#> [16,] 4.736330 4.114453
#> GACCTGGCACCGTTGG-400.2.3 GACGCGTAGCATGGCA-400.2.3
#> [1,] 4.554817 4.753201
#> [2,] 4.740864 4.147846
#> [3,] 4.283223 3.925495
#> [4,] 4.399502 3.952270
#> [5,] 4.348007 4.833527
#> [6,] 4.488372 4.435390
#> [7,] 4.724252 4.093132
#> [8,] 4.826412 4.823050
#> [9,] 4.593854 4.570431
#> [10,] 4.320598 4.360885
#> [11,] 4.619601 4.280559
#> [12,] 4.693522 4.329453
#> [13,] 4.331395 4.538999
#> [14,] 4.330565 3.912689
#> [15,] 4.316445 3.625146
#> [16,] 4.774086 4.568102
#> GACGCGTCACCTGGTG-400.2.3 GACGCGTCAGATCGGA-400.2.3
#> [1,] 3.972441 4.263822
#> [2,] 4.647638 3.800194
#> [3,] 4.608268 3.767216
#> [4,] 4.474409 4.259942
#> [5,] 4.603346 4.813773
#> [6,] 4.663386 4.059166
#> [7,] 4.027559 4.849661
#> [8,] 4.890748 4.260912
#> [9,] 5.228346 4.162949
#> [10,] 4.160433 3.847721
#> [11,] 4.069882 3.819593
#> [12,] 4.380906 3.801164
#> [13,] 4.175197 4.546072
#> [14,] 4.522638 4.438409
#> [15,] 3.807087 3.830262
#> [16,] 4.766732 3.999030
#> GACGCGTCAGGCGATA-400.2.3 GACGCGTGTCAAAGCG-400.2.3
#> [1,] 4.098330 4.757848
#> [2,] 4.293135 4.117489
#> [3,] 4.780148 3.833184
#> [4,] 4.376623 4.191928
#> [5,] 4.348794 4.835874
#> [6,] 4.035250 3.964126
#> [7,] 4.623377 4.520179
#> [8,] 4.567718 4.557848
#> [9,] 4.453618 4.352466
#> [10,] 4.038961 4.043946
#> [11,] 4.720779 4.140807
#> [12,] 4.510204 3.900448
#> [13,] 4.111317 4.441256
#> [14,] 4.155844 3.905830
#> [15,] 3.979592 4.230493
#> [16,] 4.595547 4.416143
#> GACGGCTGTATCTGCA-400.2.3 GACGGCTTCAAGGCTT-400.2.3
#> [1,] 4.345056 4.683940
#> [2,] 3.547445 3.761028
#> [3,] 3.788985 3.763597
#> [4,] 4.099536 4.078373
#> [5,] 5.160584 5.307066
#> [6,] 3.622429 4.007281
#> [7,] 4.866622 5.044968
#> [8,] 4.169210 4.301071
#> [9,] 4.171865 4.282655
#> [10,] 3.812210 3.818415
#> [11,] 4.122760 4.012848
#> [12,] 4.035169 3.787580
#> [13,] 3.936961 4.242827
#> [14,] 4.364300 4.551178
#> [15,] 3.918381 3.749465
#> [16,] 4.019907 4.014133
#> GACGTGCAGTGTACCT-400.2.3 GACGTGCGTTATTCTC-400.2.3
#> [1,] 4.326194 4.577883
#> [2,] 4.553542 3.592747
#> [3,] 4.280066 3.800238
#> [4,] 4.184514 4.314507
#> [5,] 4.684514 4.829370
#> [6,] 4.390445 3.922117
#> [7,] 4.159802 4.677170
#> [8,] 4.944811 4.447681
#> [9,] 4.626030 4.290131
#> [10,] 4.356672 3.965517
#> [11,] 4.285832 3.878716
#> [12,] 4.658979 4.118906
#> [13,] 4.464580 4.236029
#> [14,] 4.410214 4.396552
#> [15,] 4.193575 3.755054
#> [16,] 4.574959 3.929251
#> GACGTGCGTTGTCGCG-400.2.3 GACTAACGTTTGGCGC-400.2.3
#> [1,] 4.461441 3.958051
#> [2,] 4.206068 4.181326
#> [3,] 4.437421 4.284168
#> [4,] 4.249052 4.512855
#> [5,] 4.619469 4.600812
#> [6,] 4.518331 4.416779
#> [7,] 4.243995 4.102842
#> [8,] 4.702908 4.424899
#> [9,] 4.546144 4.958051
#> [10,] 4.284450 4.397835
#> [11,] 4.380531 4.077131
#> [12,] 4.324905 4.638701
#> [13,] 4.281922 4.254398
#> [14,] 3.930468 4.002706
#> [15,] 4.120101 4.322057
#> [16,] 4.546144 4.604871
#> GACTACATCAGAAATG-400.2.3 GACTACATCGTCGTTC-400.2.3
#> [1,] 4.308609 4.318443
#> [2,] 4.441060 4.006320
#> [3,] 4.340397 4.259121
#> [4,] 4.452980 4.198650
#> [5,] 4.464901 5.035622
#> [6,] 4.015894 4.103419
#> [7,] 4.509934 4.953749
#> [8,] 4.810596 4.341569
#> [9,] 5.051656 4.219334
#> [10,] 4.162914 4.027866
#> [11,] 4.652980 4.250503
#> [12,] 4.708609 4.136455
#> [13,] 4.345695 4.248061
#> [14,] 4.380132 4.349181
#> [15,] 4.209272 4.039357
#> [16,] 5.450331 4.219477
#> GACTGCGCACTTCGAA-400.2.3 GACTGCGGTCCCTTGT-400.2.3
#> [1,] 4.022145 4.187589
#> [2,] 4.370629 3.666191
#> [3,] 4.110723 3.757489
#> [4,] 4.237762 4.129815
#> [5,] 4.350816 4.677603
#> [6,] 4.221445 3.990728
#> [7,] 4.356643 5.040656
#> [8,] 4.850816 4.299572
#> [9,] 4.496503 4.109843
#> [10,] 4.447552 3.888017
#> [11,] 4.393939 3.968616
#> [12,] 4.466200 3.896576
#> [13,] 4.503497 4.338802
#> [14,] 4.304196 4.475036
#> [15,] 4.180653 3.701854
#> [16,] 4.906760 4.211840
#> GACTGCGGTCTAACGT-400.2.3 GAGCAGAGTGGGTCAA-400.2.3
#> [1,] 4.290769 4.508042
#> [2,] 4.445385 3.749290
#> [3,] 3.860000 4.099338
#> [4,] 4.053846 4.395459
#> [5,] 5.231538 5.207190
#> [6,] 3.693846 3.892148
#> [7,] 4.582308 4.761589
#> [8,] 4.973077 4.172185
#> [9,] 3.950000 4.340587
#> [10,] 3.768462 3.673605
#> [11,] 4.318462 3.964995
#> [12,] 3.815385 4.067171
#> [13,] 3.790769 4.224219
#> [14,] 4.475385 4.350047
#> [15,] 3.729231 3.873226
#> [16,] 4.415385 3.804163
#> GAGCAGATCTGCCCTA-400.2.3 GAGTCCGAGTGGACGT-400.2.3
#> [1,] 4.157303 4.346966
#> [2,] 4.357508 3.553258
#> [3,] 4.075587 3.790562
#> [4,] 4.473953 4.156404
#> [5,] 4.553626 5.308764
#> [6,] 4.216547 3.892584
#> [7,] 4.279877 5.214831
#> [8,] 4.792646 4.199101
#> [9,] 4.840654 3.847191
#> [10,] 4.050051 3.836404
#> [11,] 4.315628 4.132135
#> [12,] 4.606742 3.967640
#> [13,] 4.660878 4.264719
#> [14,] 4.170582 4.382921
#> [15,] 3.991828 3.888090
#> [16,] 4.815117 3.842247
#> GAGTCCGTCCGTAGGC-400.2.3 GATCAGTAGCTACCGC-400.2.3
#> [1,] 4.273732 4.429858
#> [2,] 4.090377 4.009294
#> [3,] 4.510403 4.362765
#> [4,] 3.847854 4.340982
#> [5,] 4.215215 5.015103
#> [6,] 4.300390 3.931746
#> [7,] 4.496099 4.749056
#> [8,] 4.610533 4.444380
#> [9,] 4.337451 4.171653
#> [10,] 3.828349 3.844612
#> [11,] 4.668401 4.168748
#> [12,] 4.492198 4.283474
#> [13,] 4.228869 4.080163
#> [14,] 4.094928 4.067383
#> [15,] 4.022757 4.214638
#> [16,] 4.055267 4.333430
#> GATCAGTTCCAGAAGG-400.2.3 GATCGATCATATACCG-400.2.3
#> [1,] 4.244413 4.436075
#> [2,] 3.883732 4.340014
#> [3,] 3.952024 4.224603
#> [4,] 4.283169 4.230822
#> [5,] 5.046414 4.723566
#> [6,] 4.111424 4.219765
#> [7,] 4.922175 4.512094
#> [8,] 4.392249 4.767795
#> [9,] 4.365995 4.419489
#> [10,] 4.124707 4.185902
#> [11,] 4.255821 4.371804
#> [12,] 3.965620 4.425017
#> [13,] 4.276918 4.365584
#> [14,] 4.324582 4.180373
#> [15,] 3.855290 4.456116
#> [16,] 4.262385 4.388390
#> GATCGATGTAGATTAG-400.2.3 GATCGCGAGCTGAACG-400.2.3
#> [1,] 4.041451 4.478070
#> [2,] 3.954663 4.421053
#> [3,] 4.411917 4.247368
#> [4,] 4.068653 4.262281
#> [5,] 4.395078 4.624561
#> [6,] 4.088083 4.281579
#> [7,] 4.682642 4.364912
#> [8,] 4.527202 4.319298
#> [9,] 4.643782 4.251754
#> [10,] 4.023316 4.337719
#> [11,] 4.183938 4.037719
#> [12,] 4.488342 4.395614
#> [13,] 4.839378 4.133333
#> [14,] 4.449482 4.121053
#> [15,] 4.033679 3.845614
#> [16,] 5.120466 4.413158
#> GATCGCGGTGCAGACA-400.2.3 GATCGTACAAAGGTGC-400.2.3
#> [1,] 4.399304 4.389541
#> [2,] 4.196169 4.210245
#> [3,] 4.169472 4.056564
#> [4,] 4.276843 4.496265
#> [5,] 4.827626 4.237994
#> [6,] 4.593151 3.918890
#> [7,] 4.387115 4.423693
#> [8,] 4.812536 4.588047
#> [9,] 4.687174 4.589114
#> [10,] 4.527568 4.456777
#> [11,] 4.486361 4.003202
#> [12,] 4.381892 4.453575
#> [13,] 3.944283 4.868730
#> [14,] 4.712710 4.103522
#> [15,] 4.164248 4.014941
#> [16,] 4.248404 4.113127
#> GATGAAACAGTCCTTC-400.2.3 GATGAGGTCAGTTGAC-400.2.3
#> [1,] 4.571034 5.001241
#> [2,] 3.754561 4.347395
#> [3,] 3.945274 4.064516
#> [4,] 4.271973 4.000000
#> [5,] 4.946932 4.615385
#> [6,] 3.658928 4.275434
#> [7,] 4.719735 3.931762
#> [8,] 4.173577 4.848635
#> [9,] 4.469320 4.904467
#> [10,] 3.844113 4.271712
#> [11,] 3.976783 4.110422
#> [12,] 4.010503 4.666253
#> [13,] 4.401327 4.863524
#> [14,] 4.391929 4.403226
#> [15,] 3.990603 4.326303
#> [16,] 4.195688 4.658809
#> GATGAGGTCTCTTGAT-400.2.3 GCAATCATCTTCATGT-400.2.3
#> [1,] 4.527127 4.180842
#> [2,] 4.111591 3.873769
#> [3,] 3.823674 4.147717
#> [4,] 4.128237 4.219338
#> [5,] 5.187423 4.905103
#> [6,] 4.175709 3.838854
#> [7,] 4.960543 5.134288
#> [8,] 4.394575 4.317816
#> [9,] 4.133785 4.130707
#> [10,] 3.826757 4.207699
#> [11,] 4.057953 4.135184
#> [12,] 3.858200 4.214861
#> [13,] 4.207768 4.169203
#> [14,] 4.548089 4.349150
#> [15,] 3.562885 3.807520
#> [16,] 4.143650 4.196956
#> GCACATACAGTCAGAG-400.2.3 GCACATAGTATAGGTA-400.2.3
#> [1,] 4.327660 4.448649
#> [2,] 4.259574 3.998198
#> [3,] 4.227964 3.841892
#> [4,] 4.089362 3.804955
#> [5,] 4.950152 5.097748
#> [6,] 4.852280 3.907658
#> [7,] 4.522796 4.227477
#> [8,] 4.864438 4.680631
#> [9,] 4.643161 4.226577
#> [10,] 4.273556 3.682432
#> [11,] 4.636474 4.260811
#> [12,] 4.499696 4.153153
#> [13,] 3.995745 4.127027
#> [14,] 4.110030 4.247297
#> [15,] 4.145289 3.882432
#> [16,] 4.533131 4.677027
#> GCAGCCACAGATGGCA-400.2.3 GCAGCCAGTACCGTAT-400.2.3
#> [1,] 4.795520 4.920807
#> [2,] 3.533601 3.597826
#> [3,] 3.796669 3.758540
#> [4,] 4.225732 4.204193
#> [5,] 5.305572 5.527950
#> [6,] 3.850661 3.807453
#> [7,] 4.647904 5.013975
#> [8,] 4.409535 4.147516
#> [9,] 4.000000 3.979037
#> [10,] 3.727743 3.841615
#> [11,] 4.209650 4.118789
#> [12,] 3.948880 3.982919
#> [13,] 4.030442 4.028727
#> [14,] 4.304423 4.191770
#> [15,] 3.927053 4.117236
#> [16,] 4.378518 4.298913
#> GCAGCCATCTTGTTTG-400.2.3 GCATACAAGTGAATTG-400.2.3
#> [1,] 4.373171 4.512801
#> [2,] 3.748780 3.774244
#> [3,] 4.166667 4.087665
#> [4,] 4.265041 4.161365
#> [5,] 4.952033 4.843289
#> [6,] 3.732520 3.926299
#> [7,] 5.039837 4.501164
#> [8,] 4.032520 4.387122
#> [9,] 4.489431 4.262219
#> [10,] 4.081301 4.107060
#> [11,] 3.808130 4.009310
#> [12,] 3.960976 4.464701
#> [13,] 4.222764 4.568658
#> [14,] 4.173171 4.197828
#> [15,] 3.880488 4.488751
#> [16,] 4.230894 4.169899
#> GCATACACAGGACCCT-400.2.3 GCATACAGTACCTACA-400.2.3
#> [1,] 4.526510 4.227181
#> [2,] 4.166461 3.896045
#> [3,] 4.408138 4.023327
#> [4,] 4.279901 4.120183
#> [5,] 4.346486 4.660243
#> [6,] 4.182491 3.855477
#> [7,] 3.848335 4.728195
#> [8,] 5.288533 4.596349
#> [9,] 4.431566 4.413793
#> [10,] 4.165228 3.877789
#> [11,] 4.311961 4.102941
#> [12,] 4.091245 4.173428
#> [13,] 4.288533 4.426471
#> [14,] 4.310727 4.259128
#> [15,] 4.235512 3.869675
#> [16,] 4.662145 4.401623
#> GCATGATGTTGTCTTT-400.2.3 GCATGCGCACGAAATA-400.2.3
#> [1,] 4.229095 4.372146
#> [2,] 4.151203 4.138128
#> [3,] 4.215349 3.959475
#> [4,] 4.372279 4.441210
#> [5,] 4.758305 4.824772
#> [6,] 4.752577 3.775685
#> [7,] 4.500573 4.053653
#> [8,] 4.747995 4.985160
#> [9,] 4.596793 4.263128
#> [10,] 4.644903 3.809361
#> [11,] 4.038946 4.181507
#> [12,] 4.429553 3.926941
#> [13,] 4.595647 4.187215
#> [14,] 4.237113 4.377854
#> [15,] 3.997709 3.857877
#> [16,] 4.483391 4.026826
#> GCATGCGGTCCAGTAT-400.2.3 GCATGCGGTGACTACT-400.2.3
#> [1,] 4.489362 4.571984
#> [2,] 3.630062 3.880156
#> [3,] 4.047358 4.284825
#> [4,] 4.460535 4.218677
#> [5,] 4.784489 4.866148
#> [6,] 3.846259 4.193774
#> [7,] 4.839396 4.507393
#> [8,] 4.251201 4.657588
#> [9,] 4.383665 4.403891
#> [10,] 3.822237 3.953307
#> [11,] 3.862045 3.958755
#> [12,] 3.824296 4.132296
#> [13,] 4.347289 4.531518
#> [14,] 4.275909 4.237354
#> [15,] 3.791352 4.097276
#> [16,] 4.008922 4.350195
#> GCATGTAAGACTACAA-400.2.3 GCATGTAGTCACAAGG-400.2.3
#> [1,] 4.347136 4.551791
#> [2,] 3.863868 4.145208
#> [3,] 4.230856 4.464666
#> [4,] 4.272263 4.330106
#> [5,] 4.657969 4.562439
#> [6,] 4.250142 4.227493
#> [7,] 4.507657 4.364956
#> [8,] 4.505956 4.582769
#> [9,] 4.470221 4.434656
#> [10,] 4.131594 4.092933
#> [11,] 4.180374 4.606002
#> [12,] 4.039138 4.269119
#> [13,] 4.296653 4.438529
#> [14,] 4.465683 4.010649
#> [15,] 4.059558 3.981607
#> [16,] 4.344299 4.551791
#> GCATGTAGTCACACGC-400.2.3 GCCTCTAAGAATTCCC-400.2.3
#> [1,] 4.922710 4.334199
#> [2,] 4.255725 4.305646
#> [3,] 3.982824 4.227125
#> [4,] 4.321565 4.090201
#> [5,] 4.736641 4.805321
#> [6,] 4.424618 4.457495
#> [7,] 4.397901 4.655419
#> [8,] 4.767176 4.401038
#> [9,] 4.624046 4.362103
#> [10,] 4.060115 4.049319
#> [11,] 4.212786 4.413368
#> [12,] 4.249046 4.088254
#> [13,] 4.494275 4.255678
#> [14,] 4.182252 4.230370
#> [15,] 3.951336 3.850746
#> [16,] 4.275763 4.459442
#> GCGAGAATCGGCGCAT-400.2.3 GCGCAACCAGCTGTAT-400.2.3
#> [1,] 4.359916 4.588435
#> [2,] 4.479538 4.376417
#> [3,] 4.250787 4.179138
#> [4,] 4.118573 4.143991
#> [5,] 4.683106 5.096372
#> [6,] 4.072403 4.461451
#> [7,] 4.222455 4.502268
#> [8,] 4.876180 4.850340
#> [9,] 4.683106 4.901361
#> [10,] 4.440714 4.055556
#> [11,] 4.249738 4.286848
#> [12,] 4.459601 4.623583
#> [13,] 4.601259 4.323129
#> [14,] 3.925498 4.105442
#> [15,] 3.810073 4.224490
#> [16,] 4.547744 4.458050
#> GCGCAGTTCGGTCCGA-400.2.3 GCGCCAACAGCCTATA-400.2.3
#> [1,] 4.409158 4.265419
#> [2,] 4.079764 4.451542
#> [3,] 4.091581 4.088106
#> [4,] 3.763663 4.264317
#> [5,] 4.838996 4.387665
#> [6,] 3.686115 4.373348
#> [7,] 4.313885 4.055066
#> [8,] 4.399557 4.977974
#> [9,] 4.184638 5.047357
#> [10,] 3.818316 4.018722
#> [11,] 3.954948 4.556167
#> [12,] 3.923191 4.441630
#> [13,] 4.401034 4.687225
#> [14,] 4.260709 4.454846
#> [15,] 3.853028 4.030837
#> [16,] 4.300591 4.694934
#> GCGGGTTTCGGAAACG-400.2.3 GCTCCTACAATCCGAT-400.2.3
#> [1,] 4.662955 4.320526
#> [2,] 3.798583 3.871587
#> [3,] 4.063765 3.783620
#> [4,] 4.798583 4.379171
#> [5,] 5.012146 4.770475
#> [6,] 3.825911 4.438827
#> [7,] 4.892713 4.960566
#> [8,] 4.365385 4.392315
#> [9,] 4.400810 4.198180
#> [10,] 3.703441 4.068756
#> [11,] 4.081984 4.247725
#> [12,] 3.971660 3.828109
#> [13,] 4.044534 4.173913
#> [14,] 4.448381 4.247725
#> [15,] 3.688259 3.992922
#> [16,] 3.966599 3.926188
#> GCTCCTATCAAACAAG-400.2.3 GCTCTGTAGGCTCTTA-400.2.3
#> [1,] 4.441176 4.670221
#> [2,] 3.607143 3.696062
#> [3,] 4.158613 3.967596
#> [4,] 4.316176 4.078343
#> [5,] 4.644433 5.148482
#> [6,] 3.912290 3.920016
#> [7,] 4.702206 4.727646
#> [8,] 4.206408 4.340033
#> [9,] 4.209034 3.952010
#> [10,] 3.784664 3.942576
#> [11,] 3.911239 3.977441
#> [12,] 4.299895 3.938884
#> [13,] 4.248424 4.210418
#> [14,] 4.246849 4.331419
#> [15,] 4.394433 4.095980
#> [16,] 4.219013 4.322395
#> GCTCTGTTCACAAACC-400.2.3 GCTCTGTTCATAAAGG-400.2.3
#> [1,] 3.984516 4.144918
#> [2,] 4.268387 4.095738
#> [3,] 4.238710 4.284590
#> [4,] 4.321290 3.594754
#> [5,] 4.926452 4.807213
#> [6,] 4.432258 3.975738
#> [7,] 4.353548 4.400656
#> [8,] 4.565161 4.814426
#> [9,] 4.402581 4.108197
#> [10,] 4.310968 4.041311
#> [11,] 4.490323 4.294426
#> [12,] 4.331613 3.944918
#> [13,] 4.285161 4.230164
#> [14,] 4.180645 4.377705
#> [15,] 4.225806 4.047869
#> [16,] 4.541935 4.371803
#> GCTGCAGCACTCTGTC-400.2.3 GCTGCTTAGATGCCAG-400.2.3
#> [1,] 4.300273 4.307276
#> [2,] 4.234759 4.009020
#> [3,] 4.345769 4.200241
#> [4,] 4.277525 4.154540
#> [5,] 4.909918 4.953698
#> [6,] 4.759782 3.889958
#> [7,] 4.336670 4.977751
#> [8,] 4.758872 4.482261
#> [9,] 4.823476 4.331930
#> [10,] 4.385805 4.003007
#> [11,] 4.491356 4.781720
#> [12,] 4.507734 4.256765
#> [13,] 4.181074 4.037883
#> [14,] 4.433121 4.433554
#> [15,] 4.380346 3.923632
#> [16,] 4.534122 4.440168
#> GCTGCTTTCGCTTAGA-400.2.3 GGAATAAGTCGTTGTA-400.2.3
#> [1,] 4.523923 4.550795
#> [2,] 3.705144 3.865930
#> [3,] 4.123206 4.066344
#> [4,] 4.178828 4.021424
#> [5,] 4.923445 4.782308
#> [6,] 4.258373 4.148583
#> [7,] 4.686603 4.396683
#> [8,] 4.261962 4.608155
#> [9,] 4.037679 4.333794
#> [10,] 3.956340 4.093296
#> [11,] 4.569378 4.079475
#> [12,] 4.142943 4.185211
#> [13,] 4.296053 4.400138
#> [14,] 4.325359 4.195577
#> [15,] 3.757775 4.111265
#> [16,] 3.928230 4.422944
#> GGAATAAGTTCAGCGC-400.2.3 GGACGTCTCGGTGTTA-400.2.3
#> [1,] 4.660735 4.424047
#> [2,] 4.043891 3.170653
#> [3,] 3.830368 3.949580
#> [4,] 3.959668 3.952165
#> [5,] 4.734282 4.791855
#> [6,] 3.619217 3.849386
#> [7,] 4.358244 4.767938
#> [8,] 4.712930 4.259858
#> [9,] 3.924081 4.226891
#> [10,] 3.778173 3.548804
#> [11,] 3.813760 3.865546
#> [12,] 4.309609 4.220427
#> [13,] 4.265718 4.102780
#> [14,] 4.347568 4.340013
#> [15,] 4.252669 4.241112
#> [16,] 4.086595 3.958630
#> GGACGTCTCGTAGATC-400.2.3 GGAGCAATCCAGTAGT-400.2.3
#> [1,] 4.612939 4.405823
#> [2,] 4.684211 4.141947
#> [3,] 4.337719 3.888990
#> [4,] 4.599781 4.547771
#> [5,] 4.547149 4.448590
#> [6,] 4.085526 4.366697
#> [7,] 4.723684 4.228389
#> [8,] 5.141447 4.677889
#> [9,] 4.361842 4.550500
#> [10,] 4.260965 4.084622
#> [11,] 4.360746 4.132848
#> [12,] 4.444079 4.438581
#> [13,] 4.462719 4.804368
#> [14,] 4.480263 4.112830
#> [15,] 4.122807 4.051865
#> [16,] 4.275219 4.250227
#> GGATGTTAGACTTGAA-400.2.3 GGATTACGTGTTCGAT-400.2.3
#> [1,] 4.407051 4.637701
#> [2,] 4.154915 4.114973
#> [3,] 4.227564 4.136364
#> [4,] 4.285256 4.191176
#> [5,] 4.388889 4.693850
#> [6,] 4.627137 4.438503
#> [7,] 4.433761 4.259358
#> [8,] 4.876068 4.663102
#> [9,] 4.480769 5.108289
#> [10,] 4.395299 4.073529
#> [11,] 4.367521 4.256684
#> [12,] 4.316239 4.542781
#> [13,] 4.154915 4.621658
#> [14,] 4.276709 4.239305
#> [15,] 4.164530 4.070856
#> [16,] 4.618590 4.724599
#> GGCCGATAGGGCATGT-400.2.3 GGCGACTCAATGGAGC-400.2.3
#> [1,] 4.517007 4.292004
#> [2,] 3.921391 4.502246
#> [3,] 4.048375 4.122192
#> [4,] 3.732426 4.447439
#> [5,] 5.226002 4.637916
#> [6,] 4.263039 4.109614
#> [7,] 5.097506 4.808625
#> [8,] 4.342404 4.734052
#> [9,] 3.993197 4.387242
#> [10,] 4.095238 4.375562
#> [11,] 4.359788 4.426774
#> [12,] 4.086924 4.513926
#> [13,] 4.179894 4.486074
#> [14,] 4.387755 4.065588
#> [15,] 3.907029 4.268643
#> [16,] 4.267574 4.751123
#> GGCGACTTCCACGACG-400.2.3 GGCGACTTCGATGAGG-400.2.3
#> [1,] 4.402056 4.593897
#> [2,] 4.133084 4.442488
#> [3,] 4.153123 4.211268
#> [4,] 4.128352 4.032864
#> [5,] 5.019396 4.392019
#> [6,] 4.222819 4.555164
#> [7,] 4.779401 3.793427
#> [8,] 4.375007 4.785211
#> [9,] 4.289770 4.665493
#> [10,] 4.169773 4.444836
#> [11,] 4.210259 4.315728
#> [12,] 4.095169 4.546948
#> [13,] 4.291874 4.345070
#> [14,] 4.315184 4.123239
#> [15,] 4.088684 4.200704
#> [16,] 4.264883 4.296948
#> GGCTCGATCTCAACTT-400.2.3 GGCTGGTAGGGAACGG-400.2.3
#> [1,] 4.428312 4.492979
#> [2,] 4.075318 4.385657
#> [3,] 4.184211 4.122869
#> [4,] 4.001815 4.104313
#> [5,] 4.690563 4.804413
#> [6,] 4.015426 4.520562
#> [7,] 4.220508 4.144433
#> [8,] 4.412886 5.009529
#> [9,] 4.233212 4.451856
#> [10,] 4.192377 4.184052
#> [11,] 3.985481 4.827984
#> [12,] 4.343920 4.319458
#> [13,] 4.587114 4.235707
#> [14,] 4.156987 4.599298
#> [15,] 4.052632 3.936309
#> [16,] 4.543557 4.291374
#> GGCTGGTCAATGAATG-400.2.3 GGCTGGTGTACCGAGA-400.2.3
#> [1,] 4.609442 4.081355
#> [2,] 3.870529 3.998832
#> [3,] 4.236767 3.951732
#> [4,] 4.442775 4.112495
#> [5,] 5.251788 5.314130
#> [6,] 3.702432 4.093811
#> [7,] 4.682403 5.009731
#> [8,] 4.532189 4.479953
#> [9,] 4.188841 4.268587
#> [10,] 3.613019 4.185675
#> [11,] 4.308298 4.174387
#> [12,] 3.957797 3.935383
#> [13,] 4.020029 4.034255
#> [14,] 4.323319 4.387699
#> [15,] 4.182403 3.996497
#> [16,] 4.670959 4.162709
#> GGCTGGTTCATACGGT-400.2.3 GGGACCTCACCGTTGG-400.2.3
#> [1,] 4.122177 4.408553
#> [2,] 4.064682 3.630263
#> [3,] 4.066735 4.100000
#> [4,] 3.850103 4.233553
#> [5,] 4.670431 4.864474
#> [6,] 3.946612 3.817763
#> [7,] 4.428131 4.714474
#> [8,] 4.659138 4.289474
#> [9,] 4.349076 3.690132
#> [10,] 4.068789 4.105263
#> [11,] 4.143737 3.651974
#> [12,] 4.236140 3.951974
#> [13,] 4.248460 4.110526
#> [14,] 3.970226 4.114474
#> [15,] 4.382957 4.156579
#> [16,] 4.365503 4.357237
#> GGGACCTGTGCTAGCC-400.2.3 GGGACCTTCGACCAGC-400.2.3
#> [1,] 4.584866 4.678507
#> [2,] 3.736209 3.489464
#> [3,] 4.059406 3.661650
#> [4,] 4.342999 4.083685
#> [5,] 4.693777 5.385912
#> [6,] 4.191655 3.574353
#> [7,] 4.652758 5.127032
#> [8,] 4.287129 4.195063
#> [9,] 3.974540 3.835039
#> [10,] 3.847949 3.565924
#> [11,] 4.340877 3.986755
#> [12,] 4.342999 3.814570
#> [13,] 4.241867 4.144491
#> [14,] 3.876238 4.123420
#> [15,] 3.785714 4.009633
#> [16,] 4.096181 4.498495
#> GGGAGATAGAAACGCC-400.2.3 GGGAGATCAGTCGATT-400.2.3
#> [1,] 4.320096 4.463141
#> [2,] 4.332130 3.442308
#> [3,] 4.334537 3.784455
#> [4,] 4.322503 3.923077
#> [5,] 4.362214 5.243590
#> [6,] 4.377858 4.053686
#> [7,] 4.606498 4.854968
#> [8,] 4.885680 4.193109
#> [9,] 4.413959 4.207532
#> [10,] 4.531889 3.654647
#> [11,] 4.148014 3.975160
#> [12,] 4.803851 4.116186
#> [13,] 4.580024 4.416667
#> [14,] 4.083032 4.518429
#> [15,] 4.227437 3.513622
#> [16,] 4.921781 3.758013
#> GGGATGAGTCGGATCC-400.2.3 GGGCACTAGCGCCTTG-400.2.3
#> [1,] 4.504132 4.430303
#> [2,] 4.432851 3.757576
#> [3,] 4.053719 4.043182
#> [4,] 4.277893 4.009848
#> [5,] 4.759298 4.855303
#> [6,] 4.509298 3.910606
#> [7,] 4.371901 4.734091
#> [8,] 4.959711 4.387121
#> [9,] 4.962810 4.372727
#> [10,] 4.297521 3.900758
#> [11,] 4.431818 4.323485
#> [12,] 4.331612 4.250000
#> [13,] 4.424587 4.141667
#> [14,] 4.401860 4.472727
#> [15,] 4.103306 3.924242
#> [16,] 4.862603 4.031061
#> GGGCATCAGACTACAA-400.2.3 GGGCATCGTCAGAATA-400.2.3
#> [1,] 4.212650 4.505758
#> [2,] 4.047983 4.147793
#> [3,] 4.078517 4.480806
#> [4,] 4.109051 4.102687
#> [5,] 4.812432 5.076775
#> [6,] 4.275900 4.553743
#> [7,] 4.836423 4.063340
#> [8,] 4.514722 5.119002
#> [9,] 4.196292 4.412668
#> [10,] 4.076336 4.320537
#> [11,] 4.252999 4.303263
#> [12,] 4.027263 4.409789
#> [13,] 4.464558 4.424184
#> [14,] 4.261723 3.983685
#> [15,] 4.065431 4.038388
#> [16,] 4.254089 4.049904
#> GGGCATCGTTGAGTTC-400.2.3 GGGTTGCGTGCACTTA-400.2.3
#> [1,] 4.744444 4.697333
#> [2,] 3.801307 4.040000
#> [3,] 4.239216 4.178667
#> [4,] 4.158824 4.109333
#> [5,] 4.704575 4.458000
#> [6,] 4.256863 3.917333
#> [7,] 4.569281 4.345333
#> [8,] 4.450980 4.222000
#> [9,] 4.020261 4.291333
#> [10,] 3.800000 3.960000
#> [11,] 4.421569 3.948000
#> [12,] 4.499346 4.066000
#> [13,] 4.272549 4.699333
#> [14,] 4.079085 4.231333
#> [15,] 4.058170 4.130000
#> [16,] 4.113725 4.502000
#> GGTATTGGTGACGCCT-400.2.3 GGTGAAGCAAAGTGCG-400.2.3
#> [1,] 4.514763 4.633192
#> [2,] 4.503209 4.401691
#> [3,] 4.451861 4.162791
#> [4,] 4.252888 4.158562
#> [5,] 4.667522 5.294926
#> [6,] 4.573813 4.908034
#> [7,] 4.272144 4.713531
#> [8,] 5.177150 5.066596
#> [9,] 4.931964 4.472516
#> [10,] 4.186136 4.237844
#> [11,] 4.293967 4.581395
#> [12,] 4.350449 4.354123
#> [13,] 4.514763 4.021142
#> [14,] 4.424904 4.167019
#> [15,] 4.055199 3.965116
#> [16,] 4.700899 4.748414
#> GGTGCGTTCACCGTAA-400.2.3 GGTGTTAAGAGCCCAA-400.2.3
#> [1,] 4.335337 4.275510
#> [2,] 3.836939 3.484694
#> [3,] 4.100561 3.684949
#> [4,] 4.265625 4.247449
#> [5,] 5.300080 4.816327
#> [6,] 3.963141 3.728316
#> [7,] 5.109776 4.922194
#> [8,] 4.264022 4.209184
#> [9,] 4.002003 4.707908
#> [10,] 3.756010 3.831633
#> [11,] 4.067708 4.085459
#> [12,] 3.970753 4.007653
#> [13,] 4.180288 4.239796
#> [14,] 4.287660 4.492347
#> [15,] 3.821715 3.903061
#> [16,] 3.951522 3.970663
#> GGTGTTACACACCGCA-400.2.3 GTAACGTGTACCGAGA-400.2.3
#> [1,] 4.298379 4.238145
#> [2,] 4.304099 4.310854
#> [3,] 3.781697 4.395153
#> [4,] 4.471878 4.269758
#> [5,] 4.530029 4.536354
#> [6,] 4.498570 4.487882
#> [7,] 4.461392 4.726027
#> [8,] 4.829361 4.586934
#> [9,] 4.569113 4.742887
#> [10,] 4.297426 4.302424
#> [11,] 4.125834 4.188620
#> [12,] 4.344137 4.761855
#> [13,] 4.672069 4.582719
#> [14,] 4.051478 3.837724
#> [15,] 3.953289 4.080084
#> [16,] 4.607245 4.537408
#> GTAACGTGTAGCTGCC-400.2.3 GTAACGTTCCCTTGTG-400.2.3
#> [1,] 4.198785 3.907527
#> [2,] 4.821181 4.209677
#> [3,] 4.494792 4.420430
#> [4,] 4.042535 3.952688
#> [5,] 4.804687 4.780645
#> [6,] 4.255208 4.215054
#> [7,] 4.448785 4.536559
#> [8,] 4.715278 4.356452
#> [9,] 4.943576 4.477419
#> [10,] 4.308160 4.144624
#> [11,] 4.426215 4.315591
#> [12,] 4.413194 4.651613
#> [13,] 4.659722 4.501613
#> [14,] 4.203993 4.113978
#> [15,] 3.887153 4.063978
#> [16,] 4.577257 4.467204
#> GTAACGTTCTAACTGG-400.2.3 GTAACTGCATAGACTC-400.2.3
#> [1,] 4.553156 4.626649
#> [2,] 4.443522 4.148417
#> [3,] 4.385382 4.130607
#> [4,] 3.953488 4.343008
#> [5,] 4.730066 4.565303
#> [6,] 4.027409 4.456464
#> [7,] 4.243355 4.224934
#> [8,] 4.715947 4.505937
#> [9,] 4.441860 4.445251
#> [10,] 4.258306 3.957784
#> [11,] 4.272425 4.251979
#> [12,] 4.210963 4.349604
#> [13,] 4.517442 4.414908
#> [14,] 4.385382 4.087071
#> [15,] 3.989203 4.042876
#> [16,] 4.651163 4.508575
#> GTACGTACACAGTCGC-400.2.3 GTACGTATCGCGCCAA-400.2.3
#> [1,] 4.227545 4.775641
#> [2,] 3.874251 3.849003
#> [3,] 3.722918 4.245726
#> [4,] 4.105607 4.342593
#> [5,] 4.953185 5.000712
#> [6,] 4.008165 4.116097
#> [7,] 4.952096 4.415954
#> [8,] 4.246598 4.267094
#> [9,] 4.157322 3.887464
#> [10,] 3.782254 4.056268
#> [11,] 3.961894 4.203704
#> [12,] 3.965161 3.977920
#> [13,] 4.440392 4.026353
#> [14,] 4.260207 4.233618
#> [15,] 3.837779 4.000000
#> [16,] 4.055525 4.550570
#> GTACGTATCTTTACAC-400.2.3 GTACTCCAGTTGTCGT-400.2.3
#> [1,] 4.732546 4.381090
#> [2,] 4.476907 3.616980
#> [3,] 3.981740 4.161602
#> [4,] 4.410311 4.149542
#> [5,] 4.703545 4.849493
#> [6,] 4.458647 3.774240
#> [7,] 4.552095 4.894838
#> [8,] 4.950591 4.279305
#> [9,] 4.504834 4.011577
#> [10,] 4.143931 3.741438
#> [11,] 4.214823 3.966233
#> [12,] 4.382385 4.166908
#> [13,] 4.524168 4.249879
#> [14,] 4.370569 4.227689
#> [15,] 4.236305 4.182827
#> [16,] 4.551020 4.318379
#> GTACTCCTCGCTTAGA-400.2.3 GTACTTTTCATCTGTT-400.2.3
#> [1,] 4.530201 4.477519
#> [2,] 3.765101 3.922481
#> [3,] 4.042953 3.979845
#> [4,] 4.340268 3.868217
#> [5,] 5.205369 5.514729
#> [6,] 3.814094 4.010078
#> [7,] 4.761745 4.926357
#> [8,] 4.322819 4.441085
#> [9,] 4.132886 4.070543
#> [10,] 3.773154 4.051938
#> [11,] 4.390604 4.151938
#> [12,] 4.189262 4.205426
#> [13,] 4.216107 4.189922
#> [14,] 4.161074 4.245736
#> [15,] 4.005369 3.900775
#> [16,] 4.525503 3.993798
#> GTAGTCAGTAGCGTGA-400.2.3 GTATCTTAGATAGTCA-400.2.3
#> [1,] 4.372218 4.351621
#> [2,] 3.726784 4.214464
#> [3,] 3.908672 4.455112
#> [4,] 4.236378 4.374065
#> [5,] 5.564850 4.188279
#> [6,] 3.924789 4.179551
#> [7,] 5.621642 4.284289
#> [8,] 4.207982 4.851621
#> [9,] 3.861090 4.609726
#> [10,] 3.771297 4.326683
#> [11,] 4.048350 4.105985
#> [12,] 4.278588 4.446384
#> [13,] 4.039908 4.532419
#> [14,] 4.244052 3.790524
#> [15,] 3.741366 4.339152
#> [16,] 4.000767 4.714464
#> GTATCTTAGATGGCGT-400.2.3 GTATTCTAGGGTGTGT-400.2.3
#> [1,] 4.540126 4.082624
#> [2,] 3.757439 4.258092
#> [3,] 4.078449 4.351789
#> [4,] 4.272317 3.873083
#> [5,] 5.122633 4.490630
#> [6,] 3.991885 4.091993
#> [7,] 4.226330 4.321976
#> [8,] 4.834986 4.601363
#> [9,] 4.238052 4.515332
#> [10,] 4.036069 4.280239
#> [11,] 3.881876 4.226576
#> [12,] 4.233544 4.187394
#> [13,] 4.288548 4.649915
#> [14,] 3.967538 4.253833
#> [15,] 4.252480 4.173765
#> [16,] 4.408476 4.904600
#> GTCAAGTCACCACCAG-400.2.3 GTCAAGTCAGCTCCGA-400.2.3
#> [1,] 4.274205 4.360636
#> [2,] 4.047302 4.474328
#> [3,] 4.303030 4.123472
#> [4,] 4.249076 4.077017
#> [5,] 4.682927 4.376528
#> [6,] 4.124169 4.568460
#> [7,] 4.693274 4.341076
#> [8,] 4.257206 4.903423
#> [9,] 4.274205 4.745721
#> [10,] 4.269032 4.006112
#> [11,] 4.283075 4.083130
#> [12,] 4.485588 4.625917
#> [13,] 4.354767 4.597800
#> [14,] 4.288248 4.288509
#> [15,] 4.312639 4.089242
#> [16,] 4.464154 5.007335
#> GTCACAACACGAAAGC-400.2.3 GTCACAATCCCTTGCA-400.2.3
#> [1,] 4.674445 4.357103
#> [2,] 3.728515 3.812256
#> [3,] 4.015367 3.810028
#> [4,] 4.022197 4.061281
#> [5,] 4.947069 5.108078
#> [6,] 3.895276 4.029526
#> [7,] 4.899829 5.060724
#> [8,] 4.403529 4.188858
#> [9,] 3.989755 3.821727
#> [10,] 3.683552 3.672981
#> [11,] 3.677860 3.933705
#> [12,] 4.269778 3.895822
#> [13,] 4.303358 4.263510
#> [14,] 4.139442 4.124234
#> [15,] 4.083665 3.830641
#> [16,] 4.110985 4.336490
#> GTCACGGCACACGCTG-400.2.3 GTCACGGTCATCGGAT-400.2.3
#> [1,] 4.366775 4.470383
#> [2,] 3.839561 4.257840
#> [3,] 4.038587 4.025552
#> [4,] 4.349310 4.422764
#> [5,] 4.848497 4.677120
#> [6,] 4.103574 4.356562
#> [7,] 4.510154 4.313589
#> [8,] 4.633225 4.706156
#> [9,] 4.307067 4.375145
#> [10,] 4.024777 4.283391
#> [11,] 4.115760 4.157956
#> [12,] 4.192526 4.602787
#> [13,] 4.374492 4.519164
#> [14,] 4.177904 4.285714
#> [15,] 3.805443 4.295006
#> [16,] 4.144598 4.988386
#> GTCATTTGTGAAGGCT-400.2.3 GTCCTCATCGCTTAGA-400.2.3
#> [1,] 3.971980 4.223007
#> [2,] 4.505604 4.065359
#> [3,] 3.745330 4.178301
#> [4,] 3.778331 4.113464
#> [5,] 5.054172 5.043399
#> [6,] 3.924658 4.167059
#> [7,] 4.872354 4.916078
#> [8,] 5.051059 4.303791
#> [9,] 4.137609 4.220654
#> [10,] 3.615193 4.017778
#> [11,] 4.460772 4.181176
#> [12,] 3.632628 4.251242
#> [13,] 3.823786 4.285752
#> [14,] 4.814446 4.425098
#> [15,] 3.514321 3.913203
#> [16,] 3.871108 4.236863
#> GTCGGGTTCTGGTATG-400.2.3 GTCTCGTAGTTAAGTG-400.2.3
#> [1,] 4.258874 4.614770
#> [2,] 3.994805 3.599468
#> [3,] 4.035498 4.060546
#> [4,] 4.171429 4.014637
#> [5,] 5.296104 5.394544
#> [6,] 4.388745 4.013972
#> [7,] 4.798268 4.934132
#> [8,] 4.435498 4.339987
#> [9,] 4.079654 4.234864
#> [10,] 4.141126 3.763806
#> [11,] 4.159307 4.339987
#> [12,] 4.334199 3.687292
#> [13,] 4.378355 4.194278
#> [14,] 4.077056 4.314039
#> [15,] 3.745455 4.110446
#> [16,] 4.329870 4.390552
#> GTCTCGTTCCATGCTC-400.2.3 GTGAAGGCATTGGTAC-400.2.3
#> [1,] 4.564941 4.372005
#> [2,] 3.741211 4.354351
#> [3,] 4.124023 3.872636
#> [4,] 4.212402 4.050441
#> [5,] 4.788574 4.725095
#> [6,] 3.981934 4.307692
#> [7,] 4.666016 4.165195
#> [8,] 4.497070 4.774275
#> [9,] 4.219238 4.462799
#> [10,] 3.883301 4.151324
#> [11,] 3.838379 4.712484
#> [12,] 4.240723 4.165195
#> [13,] 4.336914 4.291299
#> [14,] 4.160156 4.134931
#> [15,] 4.239258 3.955864
#> [16,] 4.443848 4.252207
#> GTGAAGGTCTGCGACG-400.2.3 GTGCAGCCAAGTCTAC-400.2.3
#> [1,] 4.398338 4.210345
#> [2,] 3.898977 4.296552
#> [3,] 3.961637 4.229885
#> [4,] 4.432864 4.335632
#> [5,] 5.137468 4.458621
#> [6,] 4.005754 4.543678
#> [7,] 5.182864 4.366667
#> [8,] 4.113171 4.874713
#> [9,] 3.906650 4.772414
#> [10,] 3.595908 4.387356
#> [11,] 3.924552 4.168966
#> [12,] 3.793478 4.396552
#> [13,] 4.069054 4.429885
#> [14,] 4.173913 4.326437
#> [15,] 3.604220 4.068966
#> [16,] 3.861893 4.720690
#> GTGCAGCTCCTGTAGA-400.2.3 GTGCGGTCAGCTGCAC-400.2.3
#> [1,] 4.862049 4.690842
#> [2,] 3.639382 4.102564
#> [3,] 3.957069 4.210256
#> [4,] 4.245564 4.446886
#> [5,] 5.166571 4.546520
#> [6,] 3.750429 4.147985
#> [7,] 4.606754 4.334799
#> [8,] 4.289639 4.801465
#> [9,] 4.085289 4.372161
#> [10,] 3.544934 4.076190
#> [11,] 4.144820 4.139194
#> [12,] 3.724098 4.367766
#> [13,] 3.976531 4.312821
#> [14,] 4.274184 3.833700
#> [15,] 3.914711 4.245421
#> [16,] 4.321694 4.447619
#> GTGCGGTCATCCCACT-400.2.3 GTGCGGTTCATAAAGG-400.2.3
#> [1,] 4.351908 4.387582
#> [2,] 3.474046 4.639699
#> [3,] 4.232061 4.276576
#> [4,] 4.064885 4.470367
#> [5,] 4.861069 4.522107
#> [6,] 4.125191 4.657573
#> [7,] 4.604580 4.708373
#> [8,] 4.065649 5.080903
#> [9,] 4.083969 4.958608
#> [10,] 3.636641 4.368768
#> [11,] 3.993130 4.554092
#> [12,] 4.261832 4.456256
#> [13,] 4.145802 4.067733
#> [14,] 4.487023 4.321731
#> [15,] 4.161832 4.445908
#> [16,] 3.951145 4.370649
#> GTGCTTCAGCGTCAAG-400.2.3 GTGCTTCTCACCGTAA-400.2.3
#> [1,] 4.539257 4.725316
#> [2,] 3.967133 3.713291
#> [3,] 4.183201 3.646835
#> [4,] 3.922094 4.092405
#> [5,] 4.855143 5.091139
#> [6,] 3.826537 3.924051
#> [7,] 4.431528 5.013924
#> [8,] 4.565429 4.468354
#> [9,] 4.062082 4.033544
#> [10,] 3.934267 3.754430
#> [11,] 4.496652 3.904430
#> [12,] 4.234936 3.958861
#> [13,] 4.410225 4.223418
#> [14,] 4.119294 4.408861
#> [15,] 4.116859 3.743671
#> [16,] 4.348144 4.118354
#> GTGTGCGCATCACGTA-400.2.3 GTGTGCGGTACAAGTA-400.2.3
#> [1,] 4.228306 4.698539
#> [2,] 4.137397 3.912351
#> [3,] 4.367769 4.289509
#> [4,] 4.247934 3.840637
#> [5,] 4.443182 4.571049
#> [6,] 3.964876 4.212483
#> [7,] 4.685950 4.314741
#> [8,] 4.819215 4.604250
#> [9,] 4.317149 4.302789
#> [10,] 4.297521 3.912351
#> [11,] 4.230372 4.478088
#> [12,] 4.818182 4.559097
#> [13,] 4.210744 4.586985
#> [14,] 3.930785 3.839309
#> [15,] 4.435950 4.023904
#> [16,] 4.551653 3.972112
#> GTGTGCGTCCTCATTA-400.2.3 GTGTTAGTCAGCTGGC-400.2.3
#> [1,] 4.542014 4.659306
#> [2,] 4.329296 4.064669
#> [3,] 4.296745 4.197950
#> [4,] 4.280091 4.249211
#> [5,] 4.977290 4.770505
#> [6,] 4.358819 4.010252
#> [7,] 4.642695 4.512618
#> [8,] 4.623770 4.614353
#> [9,] 4.374716 4.339905
#> [10,] 4.280848 4.084385
#> [11,] 4.082513 4.044953
#> [12,] 4.439818 3.951893
#> [13,] 4.162755 4.274448
#> [14,] 4.000000 4.245268
#> [15,] 3.963664 4.040221
#> [16,] 4.439061 4.347003
#> GTGTTAGTCGCCAAAT-400.2.3 GTTAAGCAGATGTCGG-400.2.3
#> [1,] 4.287911 4.342609
#> [2,] 4.439024 4.193623
#> [3,] 4.108696 4.467826
#> [4,] 4.402439 4.031884
#> [5,] 4.488865 4.486957
#> [6,] 4.198834 4.495652
#> [7,] 4.315483 4.155942
#> [8,] 4.519618 4.878841
#> [9,] 4.662778 4.597101
#> [10,] 4.161718 4.186667
#> [11,] 4.486744 4.284638
#> [12,] 4.466066 4.280580
#> [13,] 4.656416 4.677101
#> [14,] 4.186108 4.460870
#> [15,] 3.923118 4.230725
#> [16,] 4.563627 4.850435
#> GTTACAGTCTCTGTCG-400.2.3 GTTCGGGCAATGGAGC-400.2.3
#> [1,] 4.520231 4.373618
#> [2,] 4.315442 4.066323
#> [3,] 4.382329 3.902727
#> [4,] 4.377374 4.546057
#> [5,] 4.782824 4.476787
#> [6,] 4.345995 4.047900
#> [7,] 4.257638 4.755343
#> [8,] 4.806771 4.551953
#> [9,] 4.727498 4.210759
#> [10,] 4.526012 4.222550
#> [11,] 4.272502 4.476787
#> [12,] 4.539224 4.011791
#> [13,] 4.654831 4.349300
#> [14,] 4.203138 4.164333
#> [15,] 4.068538 3.851879
#> [16,] 5.028902 4.089167
#> GTTCTCGTCGTCCGTT-400.2.3 GTTCTCGTCTGTCTCG-400.2.3
#> [1,] 4.431365 4.596618
#> [2,] 3.986961 4.340580
#> [3,] 3.996740 4.009662
#> [4,] 4.161536 4.167874
#> [5,] 4.736327 4.905797
#> [6,] 4.069178 4.021739
#> [7,] 4.563202 3.830918
#> [8,] 4.584209 5.065217
#> [9,] 4.111554 4.601449
#> [10,] 3.879754 4.378019
#> [11,] 4.296269 4.035024
#> [12,] 3.988048 4.106280
#> [13,] 4.001811 4.942029
#> [14,] 4.480623 4.153382
#> [15,] 3.960159 3.786232
#> [16,] 4.104310 4.402174
#> TAAACCGGTCGGCACT-400.2.3 TAAACCGTCAAAGACA-400.2.3
#> [1,] 4.308068 4.957259
#> [2,] 4.187653 3.620760
#> [3,] 4.256112 3.702849
#> [4,] 4.268337 3.905020
#> [5,] 4.666259 5.251696
#> [6,] 4.095966 3.852782
#> [7,] 4.545232 4.436228
#> [8,] 4.461491 4.379240
#> [9,] 4.190709 4.245590
#> [10,] 4.070293 3.647897
#> [11,] 4.221883 4.090909
#> [12,] 4.184597 3.899593
#> [13,] 4.243276 4.032564
#> [14,] 4.086186 4.354138
#> [15,] 4.141809 3.943691
#> [16,] 4.330073 4.649932
#> TAAGCGTAGCAACGGT-400.2.3 TAAGCGTAGGCGCTCT-400.2.3
#> [1,] 4.215315 4.674598
#> [2,] 3.553450 4.123863
#> [3,] 4.067475 4.375787
#> [4,] 4.140258 3.929321
#> [5,] 4.630781 4.807558
#> [6,] 3.936315 4.078376
#> [7,] 4.964367 4.314906
#> [8,] 4.290371 4.411477
#> [9,] 4.003791 4.226732
#> [10,] 3.807430 3.979006
#> [11,] 3.969674 4.269419
#> [12,] 3.739196 4.228132
#> [13,] 4.404852 4.361092
#> [14,] 4.156937 3.895031
#> [15,] 3.934799 4.371589
#> [16,] 4.208491 4.683695
#> TAAGCGTGTCATATGC-400.2.3 TACACGAAGACCGGAT-400.2.3
#> [1,] 4.506214 4.423546
#> [2,] 4.507871 4.134243
#> [3,] 4.268434 4.344580
#> [4,] 4.205468 4.419239
#> [5,] 5.000000 4.516152
#> [6,] 4.429992 4.488873
#> [7,] 4.410936 4.529074
#> [8,] 4.857498 4.906676
#> [9,] 4.584921 4.616655
#> [10,] 4.311516 4.305097
#> [11,] 4.057995 4.569275
#> [12,] 4.497100 4.464465
#> [13,] 4.548467 3.989232
#> [14,] 4.411765 4.071070
#> [15,] 3.995857 4.143575
#> [16,] 4.594863 4.424982
#> TACAGTGAGACGCAAC-400.2.3 TACAGTGTCTGTGCAA-400.2.3
#> [1,] 4.346064 4.613293
#> [2,] 4.718628 3.995468
#> [3,] 4.201871 4.262840
#> [4,] 4.438815 4.164653
#> [5,] 4.532346 4.748489
#> [6,] 4.180047 4.091390
#> [7,] 4.553390 4.506042
#> [8,] 4.666407 4.289275
#> [9,] 4.492595 4.267372
#> [10,] 4.288387 3.979607
#> [11,] 4.588465 4.345921
#> [12,] 4.402962 3.957704
#> [13,] 4.325019 4.250755
#> [14,] 4.474669 4.337613
#> [15,] 4.242401 3.960725
#> [16,] 4.416212 4.360272
#> TACCTATAGTAGGTGC-400.2.3 TACCTATCACAGACTT-400.2.3
#> [1,] 4.412170 4.318129
#> [2,] 4.242250 4.536842
#> [3,] 4.119403 3.756725
#> [4,] 4.005741 4.416374
#> [5,] 4.707233 4.671345
#> [6,] 4.308840 4.592982
#> [7,] 4.081515 4.550877
#> [8,] 4.421355 4.966082
#> [9,] 4.359357 4.507602
#> [10,] 4.324914 4.720468
#> [11,] 4.219288 4.343860
#> [12,] 4.509759 4.083041
#> [13,] 4.557979 4.349708
#> [14,] 3.980482 4.127485
#> [15,] 4.169920 4.182456
#> [16,] 4.905855 5.183626
#> TACCTATGTGACGGTA-400.2.3 TACGGATGTCTCCCTA-400.2.3
#> [1,] 4.961092 4.078782
#> [2,] 3.567918 3.267507
#> [3,] 4.167918 3.615196
#> [4,] 4.084642 4.010504
#> [5,] 5.234812 5.502801
#> [6,] 3.896246 3.849440
#> [7,] 4.696928 5.315126
#> [8,] 4.491468 3.848389
#> [9,] 4.101024 4.032913
#> [10,] 3.899659 3.679272
#> [11,] 4.221843 3.833333
#> [12,] 3.917406 3.876401
#> [13,] 4.178840 3.991597
#> [14,] 4.308532 4.526611
#> [15,] 3.856655 3.524510
#> [16,] 4.437543 3.908613
#> TACGGGCAGTTAGCGG-400.2.3 TACGGGCTCACGGTTA-400.2.3
#> [1,] 4.587146 4.365729
#> [2,] 4.460784 4.031543
#> [3,] 3.947712 4.116795
#> [4,] 4.555556 4.385337
#> [5,] 4.881264 4.883205
#> [6,] 4.649237 3.878090
#> [7,] 4.359477 4.267690
#> [8,] 4.988017 4.798806
#> [9,] 4.601307 4.524297
#> [10,] 4.427015 4.128730
#> [11,] 4.408497 4.010230
#> [12,] 4.290850 4.103154
#> [13,] 4.461874 4.283887
#> [14,] 4.199346 3.707587
#> [15,] 3.814815 4.032396
#> [16,] 4.685185 4.420290
#> TACGGTAAGTGATCGG-400.2.3 TACTCATCACAGAGGT-400.2.3
#> [1,] 4.145007 4.541565
#> [2,] 4.347469 4.471271
#> [3,] 4.283858 4.290342
#> [4,] 4.103283 4.249389
#> [5,] 4.628591 4.588631
#> [6,] 4.162107 3.925428
#> [7,] 4.494528 4.055012
#> [8,] 4.539672 4.624083
#> [9,] 4.375513 4.297677
#> [10,] 4.104651 3.875917
#> [11,] 4.103967 4.189487
#> [12,] 4.181259 4.095966
#> [13,] 4.406293 4.344743
#> [14,] 4.047196 4.170538
#> [15,] 4.102599 4.083130
#> [16,] 4.969220 4.500000
#> TACTCGCGTAAGTTCC-400.2.3 TACTCGCTCATTTGGG-400.2.3
#> [1,] 4.246998 4.197482
#> [2,] 3.993825 3.803304
#> [3,] 4.362607 3.964595
#> [4,] 4.188679 4.123525
#> [5,] 5.139280 4.951220
#> [6,] 4.116638 3.928403
#> [7,] 4.824700 5.110936
#> [8,] 4.285763 4.618411
#> [9,] 4.081647 4.180960
#> [10,] 3.926244 4.216365
#> [11,] 4.059348 4.269079
#> [12,] 4.047684 3.938631
#> [13,] 4.262779 4.321007
#> [14,] 4.266552 4.541306
#> [15,] 4.133791 3.654603
#> [16,] 4.342367 4.019670
#> TACTTACAGTGTACTC-400.2.3 TACTTACGTGCGGTAA-400.2.3
#> [1,] 4.663700 3.804772
#> [2,] 3.808010 4.206074
#> [3,] 4.017800 4.067245
#> [4,] 4.311507 4.687636
#> [5,] 4.688493 4.549892
#> [6,] 4.268913 4.097614
#> [7,] 4.327400 4.396963
#> [8,] 4.398601 4.940347
#> [9,] 4.550540 4.675705
#> [10,] 4.060394 4.209328
#> [11,] 4.287349 4.584599
#> [12,] 4.164654 4.422993
#> [13,] 4.502861 4.284165
#> [14,] 4.148125 3.848156
#> [15,] 4.013986 3.824295
#> [16,] 4.192626 4.685466
#> TACTTGTAGGTTACCT-400.2.3 TACTTGTGTCGACTAT-400.2.3
#> [1,] 4.417219 4.693410
#> [2,] 4.644592 4.262655
#> [3,] 4.415011 4.510984
#> [4,] 4.422369 4.367717
#> [5,] 4.604121 4.384909
#> [6,] 4.462104 4.296084
#> [7,] 4.389993 4.401146
#> [8,] 4.778514 4.801337
#> [9,] 4.724062 4.532951
#> [10,] 4.521707 4.670487
#> [11,] 4.205298 4.178606
#> [12,] 4.511405 4.425024
#> [13,] 4.139809 4.247373
#> [14,] 4.391464 4.243553
#> [15,] 4.330390 4.214900
#> [16,] 4.519500 4.746896
#> TACTTGTGTTCATGGT-400.2.3 TACTTGTTCATTCACT-400.2.3
#> [1,] 4.483688 4.312907
#> [2,] 3.890780 4.032595
#> [3,] 3.858156 4.378422
#> [4,] 4.273759 4.056063
#> [5,] 4.980142 4.910691
#> [6,] 4.143262 4.112125
#> [7,] 5.195035 4.804107
#> [8,] 3.986525 4.586375
#> [9,] 4.239007 4.049218
#> [10,] 4.009929 4.057692
#> [11,] 4.275887 4.296610
#> [12,] 3.854610 4.281291
#> [13,] 4.264539 4.294980
#> [14,] 4.420567 4.139179
#> [15,] 3.897872 4.251304
#> [16,] 4.087943 4.441656
#> TAGACCAAGAGGTACC-400.2.3 TAGACCACAATCGAAA-400.2.3
#> [1,] 4.186753 4.001386
#> [2,] 4.333027 4.538568
#> [3,] 4.193192 4.065589
#> [4,] 4.195032 4.300231
#> [5,] 4.419503 5.083141
#> [6,] 4.208832 4.096998
#> [7,] 4.419503 4.683141
#> [8,] 4.853726 4.505774
#> [9,] 4.567617 4.246651
#> [10,] 4.232751 4.073903
#> [11,] 4.193192 4.473441
#> [12,] 4.574057 4.029099
#> [13,] 4.451702 4.300231
#> [14,] 4.065317 4.334411
#> [15,] 4.155474 3.644804
#> [16,] 4.857406 4.238337
#> TAGCCGGCACTCAGGC-400.2.3 TAGCCGGTCCATGAAC-400.2.3
#> [1,] 4.547972 4.796377
#> [2,] 4.279459 3.721739
#> [3,] 4.154540 4.002899
#> [4,] 4.260142 4.197101
#> [5,] 4.629749 5.060145
#> [6,] 4.415969 3.878986
#> [7,] 4.390212 4.661594
#> [8,] 4.846748 4.616667
#> [9,] 4.245332 4.031884
#> [10,] 4.524147 3.973188
#> [11,] 4.199614 4.284783
#> [12,] 4.678686 4.165942
#> [13,] 4.169994 4.300725
#> [14,] 3.831938 4.068841
#> [15,] 4.347070 4.342029
#> [16,] 4.509337 4.599275
#> TAGTGGTGTATGAAAC-400.2.3 TAGTTGGGTCTAGTCA-400.2.3
#> [1,] 4.662382 4.603220
#> [2,] 4.105548 3.815411
#> [3,] 4.276049 3.737780
#> [4,] 4.219215 4.032777
#> [5,] 5.085927 5.040253
#> [6,] 4.986468 4.258194
#> [7,] 4.570365 4.385854
#> [8,] 4.786198 4.730880
#> [9,] 4.466171 4.029327
#> [10,] 4.502706 4.001150
#> [11,] 4.642760 3.847039
#> [12,] 4.493911 4.456009
#> [13,] 3.942490 4.432432
#> [14,] 4.259134 4.096607
#> [15,] 4.221245 4.060380
#> [16,] 4.434371 3.928120
#> TAGTTGGTCAGCGACC-400.2.3 TATCAGGTCCTGCCAT-400.2.3
#> [1,] 4.338220 4.235133
#> [2,] 4.382199 4.426521
#> [3,] 4.587435 4.315789
#> [4,] 4.038743 4.436774
#> [5,] 4.808377 4.542037
#> [6,] 4.370681 4.325359
#> [7,] 4.419895 4.126452
#> [8,] 4.754974 4.724539
#> [9,] 4.531937 4.628845
#> [10,] 4.137173 4.571429
#> [11,] 4.542408 4.328776
#> [12,] 4.356021 4.330144
#> [13,] 3.788482 4.404648
#> [14,] 3.903665 4.057416
#> [15,] 4.295288 4.051265
#> [16,] 4.538220 4.683527
#> TATCAGGTCTTCCTTC-400.2.3 TATGCCCAGGTTACCT-400.2.3
#> [1,] 4.342628 4.378558
#> [2,] 4.263705 3.764706
#> [3,] 4.482042 3.999051
#> [4,] 4.262760 3.992410
#> [5,] 5.021739 5.135674
#> [6,] 4.808129 4.010436
#> [7,] 4.235822 4.963947
#> [8,] 4.980151 4.176471
#> [9,] 4.742911 4.170778
#> [10,] 4.587902 4.037951
#> [11,] 4.782609 3.939279
#> [12,] 4.457467 3.802657
#> [13,] 4.077505 4.184061
#> [14,] 4.264178 4.462998
#> [15,] 4.405009 3.559772
#> [16,] 4.545369 4.055977
#> TATGCCCGTTCCGTCT-400.2.3 TATGCCCTCACCCGAG-400.2.3
#> [1,] 4.259128 4.351894
#> [2,] 4.348645 3.992335
#> [3,] 4.352179 4.137511
#> [4,] 4.283863 4.245942
#> [5,] 4.431095 5.012849
#> [6,] 4.329800 4.052750
#> [7,] 4.376914 4.841524
#> [8,] 4.716137 4.600316
#> [9,] 4.583039 4.165915
#> [10,] 4.567727 3.954463
#> [11,] 4.100118 4.124887
#> [12,] 4.247350 4.055455
#> [13,] 4.458186 4.278629
#> [14,] 4.217903 4.168846
#> [15,] 4.275618 4.065374
#> [16,] 4.751472 4.300045
#> TATGCCCTCCGGGTGT-400.2.3 TCAACGACACAACTGT-400.2.3
#> [1,] 4.291168 4.107856
#> [2,] 4.357036 4.154461
#> [3,] 4.116766 4.423435
#> [4,] 4.255240 4.230360
#> [5,] 4.458832 5.007989
#> [6,] 4.205090 4.190413
#> [7,] 4.306886 4.312916
#> [8,] 4.841317 4.430093
#> [9,] 4.601048 4.826897
#> [10,] 4.409431 4.215712
#> [11,] 4.348802 4.491345
#> [12,] 4.326347 4.692410
#> [13,] 4.535928 4.426099
#> [14,] 3.960329 4.138482
#> [15,] 4.148204 4.057257
#> [16,] 4.500749 4.929427
#> TCAACGACACTGTTAG-400.2.3 TCAATCTAGCGTCTAT-400.2.3
#> [1,] 4.127534 4.543868
#> [2,] 4.158273 3.668495
#> [3,] 4.096795 4.081755
#> [4,] 3.968607 4.295115
#> [5,] 4.806409 4.755234
#> [6,] 4.050360 3.833500
#> [7,] 4.588620 4.792622
#> [8,] 4.385219 4.283649
#> [9,] 4.258339 3.940179
#> [10,] 4.098103 3.668993
#> [11,] 4.468934 3.784646
#> [12,] 4.045782 4.237787
#> [13,] 4.271419 4.217348
#> [14,] 4.197515 4.132602
#> [15,] 3.899281 4.166002
#> [16,] 4.556573 4.258225
#> TCAATCTCACGTAAGG-400.2.3 TCAATCTGTCCGTCAG-400.2.3
#> [1,] 4.362340 4.104807
#> [2,] 4.079646 4.068558
#> [3,] 4.253196 4.018125
#> [4,] 4.271878 4.479905
#> [5,] 4.797443 4.783294
#> [6,] 4.093412 4.177305
#> [7,] 4.285152 4.756501
#> [8,] 4.619469 4.469661
#> [9,] 4.308260 4.106383
#> [10,] 3.808751 3.903073
#> [11,] 4.143559 4.182033
#> [12,] 4.022124 3.765169
#> [13,] 4.241396 4.037825
#> [14,] 4.100295 4.152088
#> [15,] 3.936578 3.700552
#> [16,] 4.214356 4.153664
#> TCACGAAGTCCGCTGA-400.2.3 TCACGAATCGTAGGAG-400.2.3
#> [1,] 4.414414 4.371520
#> [2,] 4.129880 4.153105
#> [3,] 4.298048 4.138116
#> [4,] 4.307057 4.115632
#> [5,] 4.674174 4.594218
#> [6,] 4.551802 4.506424
#> [7,] 4.400901 4.268737
#> [8,] 4.794294 5.004283
#> [9,] 4.644144 4.513919
#> [10,] 4.414414 4.614561
#> [11,] 4.569069 4.552463
#> [12,] 4.442943 4.387580
#> [13,] 3.969970 4.490364
#> [14,] 4.300300 3.973233
#> [15,] 4.373874 3.993576
#> [16,] 4.394144 4.414347
#> TCAGATGAGAATTGTG-400.2.3 TCAGCAAAGCAACGGT-400.2.3
#> [1,] 4.192417 4.843284
#> [2,] 4.395261 3.575093
#> [3,] 4.291943 3.997668
#> [4,] 4.387678 4.111474
#> [5,] 4.530806 5.083489
#> [6,] 4.512796 4.237873
#> [7,] 4.291943 4.645989
#> [8,] 4.854028 4.395056
#> [9,] 4.462559 4.139925
#> [10,] 4.692891 3.737407
#> [11,] 4.413270 4.211287
#> [12,] 4.302370 3.977612
#> [13,] 4.575355 4.279384
#> [14,] 4.243602 4.235541
#> [15,] 4.181043 3.919310
#> [16,] 4.583886 3.791511
#> TCAGCAACACGGTAAG-400.2.3 TCAGCAAGTACAGTTC-400.2.3
#> [1,] 4.426382 4.184264
#> [2,] 3.538308 4.459314
#> [3,] 3.918721 4.140551
#> [4,] 4.398401 4.156019
#> [5,] 5.238508 4.692670
#> [6,] 3.912725 4.357767
#> [7,] 4.977348 4.349697
#> [8,] 4.390406 4.720915
#> [9,] 4.045969 4.512441
#> [10,] 3.912059 4.510424
#> [11,] 3.942705 4.291863
#> [12,] 3.946702 4.714190
#> [13,] 4.346436 4.193679
#> [14,] 4.136576 4.238736
#> [15,] 3.827448 4.408877
#> [16,] 3.867422 4.442502
#> TCAGCTCCAGATCCAT-400.2.3 TCAGCTCTCAGCGATT-400.2.3
#> [1,] 4.500000 4.503259
#> [2,] 4.548469 3.967129
#> [3,] 4.254252 4.408614
#> [4,] 4.399660 4.065174
#> [5,] 4.884354 4.577784
#> [6,] 4.554422 4.272032
#> [7,] 4.865646 4.266081
#> [8,] 4.488095 4.429583
#> [9,] 4.414966 4.306036
#> [10,] 4.456633 4.062057
#> [11,] 4.164966 4.281383
#> [12,] 4.428571 4.260414
#> [13,] 4.130102 4.205724
#> [14,] 4.281463 4.377161
#> [15,] 4.396259 4.229810
#> [16,] 4.204932 4.360159
#> TCAGGATCACACTGCG-400.2.3 TCAGGATGTGATGATA-400.2.3
#> [1,] 4.133014 4.304762
#> [2,] 3.963636 3.438730
#> [3,] 4.006699 3.822222
#> [4,] 4.102392 4.144127
#> [5,] 4.774163 5.058413
#> [6,] 3.863158 4.092698
#> [7,] 4.508134 4.721905
#> [8,] 4.569378 4.149206
#> [9,] 4.280383 4.335873
#> [10,] 4.240191 3.508571
#> [11,] 4.088995 4.347937
#> [12,] 3.894737 3.836825
#> [13,] 4.351196 4.216508
#> [14,] 4.151196 4.322540
#> [15,] 4.012440 3.768254
#> [16,] 4.091866 3.963810
#> TCAGGTAGTTCAACCA-400.2.3 TCATTTGAGCCGGTAA-400.2.3
#> [1,] 4.253408 4.636964
#> [2,] 4.485164 3.554455
#> [3,] 4.383320 3.826403
#> [4,] 4.060144 4.077228
#> [5,] 4.831596 4.612541
#> [6,] 4.172414 4.200000
#> [7,] 4.287891 4.324752
#> [8,] 4.517241 4.540594
#> [9,] 4.479551 4.331353
#> [10,] 4.246191 3.825083
#> [11,] 4.513232 4.271947
#> [12,] 4.324779 4.381518
#> [13,] 4.239775 4.316832
#> [14,] 4.083400 4.088449
#> [15,] 3.901363 4.086469
#> [16,] 4.710505 4.094389
#> TCATTTGTCGGGAGTA-400.2.3 TCCACACAGCTGCCCA-400.2.3
#> [1,] 4.277155 4.440395
#> [2,] 4.840742 4.177270
#> [3,] 4.091612 4.575046
#> [4,] 3.977580 4.441013
#> [5,] 4.659838 5.068561
#> [6,] 3.992656 4.363805
#> [7,] 4.073831 4.888203
#> [8,] 5.033630 4.189006
#> [9,] 4.178972 4.078443
#> [10,] 4.136451 3.953057
#> [11,] 4.649401 4.234713
#> [12,] 4.226517 4.401482
#> [13,] 4.230769 4.304509
#> [14,] 4.702744 3.919086
#> [15,] 3.888288 4.209389
#> [16,] 4.467723 3.864114
#> TCCACACAGTACTTGC-400.2.3 TCCACACCACATCCGG-400.2.3
#> [1,] 4.680934 4.579137
#> [2,] 3.625162 3.895683
#> [3,] 4.084955 4.502698
#> [4,] 4.162776 4.428058
#> [5,] 5.204929 4.832734
#> [6,] 4.107004 4.250000
#> [7,] 4.954821 4.313849
#> [8,] 4.292910 4.469424
#> [9,] 3.960009 4.317446
#> [10,] 3.859058 4.111511
#> [11,] 4.238219 4.393885
#> [12,] 3.981193 4.296763
#> [13,] 4.154777 4.364209
#> [14,] 4.212927 4.226619
#> [15,] 3.811500 4.232014
#> [16,] 4.116948 4.042266
#> TCCACACTCCCACTTG-400.2.3 TCCACACTCGAGAGCA-400.2.3
#> [1,] 4.315445 4.443716
#> [2,] 4.480366 4.039891
#> [3,] 4.382199 4.168852
#> [4,] 4.221204 4.285519
#> [5,] 4.490838 4.542623
#> [6,] 4.373037 4.318033
#> [7,] 4.208115 4.296721
#> [8,] 4.620419 4.784426
#> [9,] 4.650524 4.528689
#> [10,] 4.094241 4.228962
#> [11,] 4.250000 4.304918
#> [12,] 4.561518 4.358470
#> [13,] 4.342932 4.330601
#> [14,] 4.078534 4.157923
#> [15,] 4.236911 4.201093
#> [16,] 4.535340 4.285519
#> TCCCGATCAGAAGCAC-400.2.3 TCGAGGCGTAAGTGGC-400.2.3
#> [1,] 4.148841 4.230947
#> [2,] 4.327986 3.944958
#> [3,] 4.256684 4.203233
#> [4,] 4.286096 4.120092
#> [5,] 4.803030 5.089684
#> [6,] 4.479501 4.037336
#> [7,] 4.447415 4.961894
#> [8,] 5.103387 4.273287
#> [9,] 4.921569 4.171286
#> [10,] 4.295900 3.924557
#> [11,] 4.063280 4.147806
#> [12,] 4.852941 4.255966
#> [13,] 4.508021 4.241339
#> [14,] 4.374332 4.243264
#> [15,] 4.218360 4.031948
#> [16,] 4.319964 4.098922
#> TCGCGTTTCCCTAATT-400.2.3 TCGGGACAGCAGATCG-400.2.3
#> [1,] 4.476829 4.620204
#> [2,] 4.451220 3.651527
#> [3,] 4.530488 3.787784
#> [4,] 4.400000 4.305403
#> [5,] 5.141463 5.238058
#> [6,] 4.537805 4.031323
#> [7,] 4.476829 4.841817
#> [8,] 5.101220 4.464370
#> [9,] 4.613415 4.047768
#> [10,] 4.454878 4.069695
#> [11,] 4.476829 3.906030
#> [12,] 4.771951 3.969460
#> [13,] 4.073171 4.537980
#> [14,] 4.109756 4.185591
#> [15,] 4.179268 3.826155
#> [16,] 4.626829 4.150352
#> TCGGGACAGCCCAGCT-400.2.3 TCGGGACGTACCGTAT-400.2.3
#> [1,] 4.541836 4.378278
#> [2,] 3.987815 4.208666
#> [3,] 4.456539 4.474344
#> [4,] 4.406986 4.178164
#> [5,] 4.755483 4.690137
#> [6,] 4.082047 4.256271
#> [7,] 4.064988 4.206956
#> [8,] 4.637693 4.750570
#> [9,] 4.415922 4.590365
#> [10,] 3.957758 4.080958
#> [11,] 4.119415 4.150798
#> [12,] 4.595451 4.270525
#> [13,] 4.338749 4.476625
#> [14,] 4.031682 4.196693
#> [15,] 4.230707 4.148803
#> [16,] 4.411860 4.475770
#> TCGGTAACACATGGGA-400.2.3 TCGGTAAGTAACGACG-400.2.3
#> [1,] 4.174680 4.612457
#> [2,] 3.644023 3.824221
#> [3,] 3.967358 4.110035
#> [4,] 4.205558 4.481661
#> [5,] 5.570798 4.601384
#> [6,] 4.183502 3.892734
#> [7,] 5.085576 4.476817
#> [8,] 3.930745 4.494118
#> [9,] 4.022056 4.286505
#> [10,] 3.841641 4.017993
#> [11,] 4.019409 3.734256
#> [12,] 3.980591 4.168858
#> [13,] 4.460521 4.267128
#> [14,] 4.253198 4.289965
#> [15,] 3.656374 4.035294
#> [16,] 4.008381 4.186851
#> TCGTACCCACCTTGTC-400.2.3 TCTATTGGTTGGAGGT-400.2.3
#> [1,] 4.776066 4.573798
#> [2,] 4.415284 4.296849
#> [3,] 4.620261 3.981758
#> [4,] 4.234005 4.173300
#> [5,] 4.875592 4.622720
#> [6,] 4.076422 4.392206
#> [7,] 4.386848 4.203980
#> [8,] 4.545024 4.501658
#> [9,] 4.279621 4.211443
#> [10,] 4.141588 4.354892
#> [11,] 4.293246 4.173300
#> [12,] 4.113744 4.452736
#> [13,] 4.330569 4.223051
#> [14,] 4.120261 4.083748
#> [15,] 4.424763 4.228856
#> [16,] 4.661137 4.470149
#> TCTATTGTCCGTAGTA-400.2.3 TCTCATAAGTATGACA-400.2.3
#> [1,] 4.344287 4.241408
#> [2,] 4.370426 4.496228
#> [3,] 4.302465 4.165968
#> [4,] 4.224048 4.267393
#> [5,] 4.866318 4.467728
#> [6,] 4.070202 4.156748
#> [7,] 4.318895 4.740151
#> [8,] 4.517550 4.847443
#> [9,] 4.693055 4.477787
#> [10,] 4.335325 4.365465
#> [11,] 4.222554 4.738474
#> [12,] 4.580284 4.684828
#> [13,] 4.744586 4.421626
#> [14,] 4.170276 3.971500
#> [15,] 4.014190 4.327745
#> [16,] 4.563107 4.740989
#> TCTGAGACAATCGGTT-400.2.3 TCTGGAATCACGCGGT-400.2.3
#> [1,] 4.383832 4.995327
#> [2,] 3.861871 4.332944
#> [3,] 3.931891 4.377336
#> [4,] 4.175684 4.272196
#> [5,] 5.520687 4.550234
#> [6,] 3.923616 4.445093
#> [7,] 5.080204 4.370327
#> [8,] 4.397199 5.254673
#> [9,] 3.943348 4.804907
#> [10,] 3.747931 4.443925
#> [11,] 4.205602 4.467290
#> [12,] 4.026098 4.470794
#> [13,] 4.164863 4.259346
#> [14,] 4.220878 4.778037
#> [15,] 3.731381 4.234813
#> [16,] 3.955442 4.586449
#> TCTTCGGCAATTCCTT-400.2.3 TCTTCGGCACATCCAA-400.2.3
#> [1,] 4.423756 4.561343
#> [2,] 4.212841 3.857639
#> [3,] 4.107544 3.838542
#> [4,] 4.326485 4.020833
#> [5,] 4.984270 5.087963
#> [6,] 4.264848 4.157986
#> [7,] 4.597753 4.861690
#> [8,] 4.693419 4.105903
#> [9,] 4.354093 4.172454
#> [10,] 4.067095 4.061921
#> [11,] 4.052006 3.888889
#> [12,] 4.175281 3.958333
#> [13,] 4.173355 4.309606
#> [14,] 4.116533 4.482060
#> [15,] 3.931300 3.718171
#> [16,] 4.526485 4.280671
#> TCTTTCCCATAAAGGT-400.2.3 TCTTTCCGTCGGCATC-400.2.3
#> [1,] 4.731383 4.452020
#> [2,] 4.374113 4.123737
#> [3,] 4.483156 4.020833
#> [4,] 4.260638 4.351641
#> [5,] 4.707447 4.952652
#> [6,] 4.396277 4.084596
#> [7,] 4.408688 4.386364
#> [8,] 4.687057 4.667298
#> [9,] 4.636525 4.465278
#> [10,] 4.218085 3.987374
#> [11,] 4.164894 3.895202
#> [12,] 4.474291 4.260732
#> [13,] 4.184397 4.429924
#> [14,] 4.023050 4.117424
#> [15,] 4.020390 4.000000
#> [16,] 4.373227 4.318813
#> TGAAAGAAGTTTGCGT-400.2.3 TGACAACTCCTACAGA-400.2.3
#> [1,] 4.453579 4.313701
#> [2,] 4.306875 3.791692
#> [3,] 4.128278 3.893986
#> [4,] 4.370305 4.283943
#> [5,] 4.463501 5.137632
#> [6,] 4.380936 3.911965
#> [7,] 4.220411 4.900806
#> [8,] 4.793055 4.384997
#> [9,] 4.525514 3.924985
#> [10,] 4.281361 3.745195
#> [11,] 4.069100 4.046497
#> [12,] 4.561304 3.787973
#> [13,] 4.375266 4.174210
#> [14,] 4.092133 4.311841
#> [15,] 4.187456 3.720397
#> [16,] 4.653792 4.246125
#> TGACGGCCAGAAGCAC-400.2.3 TGACGGCGTCCAAGTT-400.2.3
#> [1,] 4.673123 4.301144
#> [2,] 4.601695 4.656925
#> [3,] 4.154964 4.330368
#> [4,] 4.381356 4.510801
#> [5,] 4.995157 4.595934
#> [6,] 4.531477 4.176620
#> [7,] 4.184019 4.160102
#> [8,] 4.727603 5.203304
#> [9,] 4.799031 4.603558
#> [10,] 4.157385 4.588310
#> [11,] 4.279661 4.114358
#> [12,] 4.445521 4.297332
#> [13,] 4.629540 4.282084
#> [14,] 4.300242 4.067344
#> [15,] 4.105327 4.149936
#> [16,] 4.751816 4.580686
#> TGACTAGCATCCGCGA-400.2.3 TGACTAGGTCCCTTGT-400.2.3
#> [1,] 4.341040 4.648579
#> [2,] 4.138284 4.338501
#> [3,] 4.339707 4.170543
#> [4,] 4.300578 4.192506
#> [5,] 4.584704 4.441860
#> [6,] 4.402846 4.369509
#> [7,] 4.448199 4.476744
#> [8,] 4.477546 4.808786
#> [9,] 4.502446 4.500000
#> [10,] 4.205869 4.227390
#> [11,] 4.297021 4.148579
#> [12,] 4.329924 4.629199
#> [13,] 4.238773 4.733850
#> [14,] 4.126278 4.281654
#> [15,] 4.091596 3.953488
#> [16,] 4.480213 5.028424
#> TGAGCATCATGGTTGT-400.2.3 TGAGCATTCACAAACC-400.2.3
#> [1,] 4.280470 4.576779
#> [2,] 4.486050 3.976280
#> [3,] 4.190162 4.284644
#> [4,] 4.401615 3.866417
#> [5,] 4.460352 4.684145
#> [6,] 4.270925 4.461923
#> [7,] 4.132159 4.292135
#> [8,] 4.790749 5.077403
#> [9,] 5.046256 4.978777
#> [10,] 4.320852 3.815231
#> [11,] 4.166667 4.202247
#> [12,] 4.480910 4.463171
#> [13,] 4.369310 4.717853
#> [14,] 4.234949 3.958801
#> [15,] 4.125551 4.021223
#> [16,] 4.883260 4.569288
#> TGAGCATTCCGGGTGT-400.2.3 TGAGCCGGTCGGATCC-400.2.3
#> [1,] 4.330698 4.300752
#> [2,] 4.175889 4.474937
#> [3,] 4.185771 4.196742
#> [4,] 4.208169 4.017544
#> [5,] 4.994071 4.602757
#> [6,] 4.183136 4.355890
#> [7,] 4.513834 4.219298
#> [8,] 4.893939 4.788221
#> [9,] 4.243742 4.558897
#> [10,] 4.005270 4.401003
#> [11,] 4.161397 4.248120
#> [12,] 4.306983 4.482456
#> [13,] 4.270751 4.294486
#> [14,] 4.188406 4.144110
#> [15,] 4.132411 4.161654
#> [16,] 4.427536 4.942356
#> TGAGGGAAGGAGCGTT-400.2.3 TGAGGGACAGGCTGAA-400.2.3
#> [1,] 4.091716 4.670569
#> [2,] 3.730769 3.572464
#> [3,] 3.511834 4.191750
#> [4,] 4.024655 4.350056
#> [5,] 5.304734 4.929766
#> [6,] 3.799803 4.081940
#> [7,] 5.098619 4.838907
#> [8,] 4.613412 4.195095
#> [9,] 4.081854 4.090858
#> [10,] 3.415187 3.762542
#> [11,] 4.151874 3.928094
#> [12,] 3.635108 4.025084
#> [13,] 3.938856 4.240803
#> [14,] 4.591716 4.369565
#> [15,] 3.346154 4.179487
#> [16,] 4.022682 4.240245
#> TGATTTCAGGTTACCT-400.2.3 TGATTTCCATCACGTA-400.2.3
#> [1,] 4.192059 4.800000
#> [2,] 4.263158 3.620657
#> [3,] 4.079409 3.836620
#> [4,] 4.209603 4.228169
#> [5,] 4.724838 5.476995
#> [6,] 4.602955 3.796244
#> [7,] 4.403509 4.825822
#> [8,] 5.094183 4.325822
#> [9,] 4.927978 3.768545
#> [10,] 4.206833 3.739437
#> [11,] 4.591874 4.282160
#> [12,] 4.587258 3.637559
#> [13,] 4.551247 4.032394
#> [14,] 4.111727 4.186854
#> [15,] 4.110803 3.831455
#> [16,] 4.588181 4.321596
#> TGATTTCGTGACGCCT-400.2.3 TGCCAAACACCATGTA-400.2.3
#> [1,] 4.358783 4.590860
#> [2,] 3.952824 3.423830
#> [3,] 4.140906 3.627856
#> [4,] 4.492241 4.463547
#> [5,] 5.101179 4.953754
#> [6,] 3.977654 3.756257
#> [7,] 4.891993 4.984766
#> [8,] 4.304159 4.247552
#> [9,] 4.174426 3.971708
#> [10,] 4.007449 3.656692
#> [11,] 4.096214 3.827530
#> [12,] 3.931719 3.976061
#> [13,] 4.298572 4.079434
#> [14,] 3.924271 4.113166
#> [15,] 3.877095 4.130577
#> [16,] 4.048417 4.105550
#> TGCCCATAGATCGATA-400.2.3 TGCCCATAGCCGGTAA-400.2.3
#> [1,] 4.150240 4.468464
#> [2,] 4.167067 3.984689
#> [3,] 4.258413 3.940585
#> [4,] 4.459135 4.326554
#> [5,] 4.139423 5.080667
#> [6,] 4.543269 4.267367
#> [7,] 4.649038 4.734461
#> [8,] 4.674279 4.412477
#> [9,] 4.518029 4.108547
#> [10,] 4.671875 4.210923
#> [11,] 4.200721 3.838208
#> [12,] 4.311298 4.049360
#> [13,] 4.287260 4.445612
#> [14,] 4.312500 4.247029
#> [15,] 4.459135 3.858318
#> [16,] 4.741587 4.280622
#> TGCCCTATCTGGTTCC-400.2.3 TGCGCAGAGCGTGTCC-400.2.3
#> [1,] 4.634047 4.207506
#> [2,] 3.702854 4.411700
#> [3,] 4.009684 4.144592
#> [4,] 4.135066 4.373068
#> [5,] 5.183996 4.560706
#> [6,] 3.823649 4.020971
#> [7,] 5.029052 4.757174
#> [8,] 4.322120 4.825607
#> [9,] 4.140163 4.455850
#> [10,] 3.991845 4.268212
#> [11,] 3.986748 4.403974
#> [12,] 3.926096 4.849890
#> [13,] 4.109072 4.397351
#> [14,] 4.350153 4.535320
#> [15,] 3.990826 4.103753
#> [16,] 4.373598 4.737307
#> TGCGCAGGTAACGTTC-400.2.3 TGCGGGTTCACTGGGC-400.2.3
#> [1,] 4.786577 4.266319
#> [2,] 4.363758 4.288947
#> [3,] 4.308725 4.188860
#> [4,] 4.104698 4.010444
#> [5,] 4.479195 4.853786
#> [6,] 4.481879 4.395126
#> [7,] 4.522148 4.355962
#> [8,] 5.127517 4.731941
#> [9,] 4.974497 4.475196
#> [10,] 4.404027 4.190601
#> [11,] 4.464430 4.329852
#> [12,] 4.573154 4.464752
#> [13,] 4.838926 4.663185
#> [14,] 4.075168 4.259356
#> [15,] 4.151678 4.078329
#> [16,] 4.641611 4.248042
#> TGCGGGTTCGATGAGG-400.2.3 TGCGTGGAGGAGTTGC-400.2.3
#> [1,] 4.747812 4.378698
#> [2,] 3.571201 3.870562
#> [3,] 3.903739 3.960059
#> [4,] 4.198091 4.159763
#> [5,] 4.815434 4.700444
#> [6,] 3.800318 3.889053
#> [7,] 4.805887 4.592456
#> [8,] 4.168656 4.409763
#> [9,] 4.485282 4.227071
#> [10,] 4.004773 3.969675
#> [11,] 3.831344 3.781065
#> [12,] 4.077168 4.338757
#> [13,] 4.369928 4.221893
#> [14,] 4.412092 4.363905
#> [15,] 4.044551 3.871302
#> [16,] 3.983294 4.332840
#> TGCGTGGCATGTCTCC-400.2.3 TGCGTGGTCTCAAGTG-400.2.3
#> [1,] 4.211344 4.571069
#> [2,] 4.085470 4.325786
#> [3,] 4.465423 4.215094
#> [4,] 4.034188 4.591195
#> [5,] 4.708625 4.660377
#> [6,] 4.267288 4.184906
#> [7,] 4.423465 4.176101
#> [8,] 4.723388 4.450314
#> [9,] 4.427350 4.574843
#> [10,] 4.313908 4.345912
#> [11,] 3.986014 4.051572
#> [12,] 4.387723 4.503145
#> [13,] 4.313908 4.693082
#> [14,] 4.178710 4.364780
#> [15,] 4.068376 4.132075
#> [16,] 4.360528 4.664151
#> TGCTACCTCCGCGCAA-400.2.3 TGCTGCTCAGCTGTAT-400.2.3
#> [1,] 4.397899 4.724371
#> [2,] 3.973079 3.950989
#> [3,] 4.254760 4.017086
#> [4,] 3.954038 4.348471
#> [5,] 4.476691 4.638939
#> [6,] 4.213395 4.198741
#> [7,] 4.287590 4.684802
#> [8,] 4.776100 4.610612
#> [9,] 4.571898 4.589928
#> [10,] 4.066973 4.223921
#> [11,] 4.144452 4.092626
#> [12,] 4.524622 4.457284
#> [13,] 4.518713 4.375000
#> [14,] 4.197636 4.361511
#> [15,] 4.258043 3.813399
#> [16,] 4.474721 4.392086
#> TGCTGCTTCGCTAGCG-400.2.3 TGGACGCAGATCGGGT-400.2.3
#> [1,] 4.263099 4.625714
#> [2,] 4.326644 3.628571
#> [3,] 4.386845 4.134286
#> [4,] 4.327759 3.922857
#> [5,] 4.542921 4.246429
#> [6,] 4.589744 4.257143
#> [7,] 4.178372 4.585000
#> [8,] 4.762542 4.702143
#> [9,] 4.441472 4.318571
#> [10,] 4.413601 3.854286
#> [11,] 4.101449 4.426429
#> [12,] 4.365663 4.353571
#> [13,] 4.383501 4.383571
#> [14,] 4.550725 4.227857
#> [15,] 4.141583 3.692143
#> [16,] 4.362319 4.052857
#> TGGACGCCACGAAACG-400.2.3 TGGCCAGAGATGTAAC-400.2.3
#> [1,] 4.544479 4.489860
#> [2,] 3.880368 4.282371
#> [3,] 4.184049 4.300312
#> [4,] 4.313906 4.364275
#> [5,] 4.966769 4.315913
#> [6,] 4.126278 4.616225
#> [7,] 4.660020 4.485179
#> [8,] 4.331288 5.014821
#> [9,] 4.015849 4.639626
#> [10,] 3.778119 4.546802
#> [11,] 3.965235 4.529641
#> [12,] 4.275051 4.478939
#> [13,] 4.091002 4.271451
#> [14,] 4.092536 4.361934
#> [15,] 4.223415 4.300312
#> [16,] 4.335378 4.281591
#> TGGCCAGCAATAGAGT-400.2.3 TGGCCAGCATTGCGGC-400.2.3
#> [1,] 4.304389 4.335211
#> [2,] 4.458015 4.236620
#> [3,] 3.789122 4.169014
#> [4,] 4.350191 3.847887
#> [5,] 4.740458 4.607512
#> [6,] 4.505725 4.449765
#> [7,] 4.155534 4.031925
#> [8,] 5.042939 4.498592
#> [9,] 4.393130 4.237559
#> [10,] 4.683206 4.565258
#> [11,] 4.640267 4.217840
#> [12,] 4.492366 4.139906
#> [13,] 4.161260 4.536150
#> [14,] 3.956107 4.333333
#> [15,] 3.759542 4.011268
#> [16,] 4.284351 4.584977
#> TGGCGCACATGACATC-400.2.3 TGGCGCATCTGAGGGA-400.2.3
#> [1,] 4.313637 4.319912
#> [2,] 3.864357 3.874817
#> [3,] 4.003784 4.297950
#> [4,] 4.146849 4.043192
#> [5,] 5.052249 4.766471
#> [6,] 4.255712 4.018302
#> [7,] 5.008878 4.926794
#> [8,] 4.216126 4.313324
#> [9,] 4.433125 4.325769
#> [10,] 4.018775 3.972914
#> [11,] 4.278417 4.308931
#> [12,] 4.082521 4.336018
#> [13,] 4.118614 4.155930
#> [14,] 4.334304 4.265007
#> [15,] 3.787367 4.282577
#> [16,] 4.460777 4.281845
#> TGGCTGGGTAGCTAAA-400.2.3 TGGCTGGGTTCCACAA-400.2.3
#> [1,] 4.367746 4.676032
#> [2,] 4.136225 3.934633
#> [3,] 4.191203 4.479931
#> [4,] 4.154551 4.461583
#> [5,] 4.486255 4.755734
#> [6,] 4.949908 3.918005
#> [7,] 4.541845 4.741399
#> [8,] 4.737935 4.122706
#> [9,] 4.553451 3.975917
#> [10,] 4.321930 3.873280
#> [11,] 4.662798 4.103211
#> [12,] 4.442272 4.291858
#> [13,] 3.787416 4.155963
#> [14,] 3.989615 4.117546
#> [15,] 4.117899 3.948968
#> [16,] 4.365302 4.297592
#> TGGCTGGTCCCAAGAT-400.2.3 TGGGAAGAGTATCGAA-400.2.3
#> [1,] 4.274593 4.644276
#> [2,] 4.439490 3.848715
#> [3,] 4.550602 3.997664
#> [4,] 4.230715 3.888435
#> [5,] 4.957537 4.752921
#> [6,] 4.773531 4.412967
#> [7,] 4.240623 4.429322
#> [8,] 4.687190 4.376752
#> [9,] 4.723992 4.230724
#> [10,] 4.135173 3.953855
#> [11,] 4.157820 4.637850
#> [12,] 4.242038 4.411215
#> [13,] 4.276716 4.334696
#> [14,] 4.031847 4.102220
#> [15,] 4.163482 3.976636
#> [16,] 4.658882 4.185748
#> TGGGAAGGTAATCACC-400.2.3 TGGGCGTGTGTCCTCT-400.2.3
#> [1,] 4.361456 4.453195
#> [2,] 4.137304 3.852897
#> [3,] 4.014888 4.045319
#> [4,] 4.232423 4.612927
#> [5,] 4.385443 5.193165
#> [6,] 4.178660 4.073551
#> [7,] 4.501241 5.051263
#> [8,] 4.709677 4.080981
#> [9,] 4.162117 3.861070
#> [10,] 3.997519 3.790490
#> [11,] 4.085194 4.177563
#> [12,] 4.082713 4.060921
#> [13,] 4.498759 4.277117
#> [14,] 3.902399 3.858098
#> [15,] 3.971878 3.687964
#> [16,] 4.375517 3.807578
#> TGGGCGTGTTATCACG-400.2.3 TGGTTAGAGCTGCCCA-400.2.3
#> [1,] 4.255232 4.552389
#> [2,] 4.057896 4.241408
#> [3,] 4.133188 4.398994
#> [4,] 4.217994 4.332775
#> [5,] 4.979614 4.549036
#> [6,] 4.108725 3.943001
#> [7,] 4.710519 4.212070
#> [8,] 4.461267 4.599329
#> [9,] 4.318837 4.175189
#> [10,] 4.124490 3.937133
#> [11,] 4.302800 4.308466
#> [12,] 3.997825 4.261526
#> [13,] 4.312313 4.087175
#> [14,] 4.439522 4.222967
#> [15,] 3.834194 4.337804
#> [16,] 4.154390 4.356245
#> TGGTTAGGTCTCCACT-400.2.3 TGGTTCCTCTTTACGT-400.2.3
#> [1,] 4.543236 4.331849
#> [2,] 4.145700 3.930958
#> [3,] 4.241886 3.930958
#> [4,] 4.768538 4.345212
#> [5,] 4.597726 4.286192
#> [6,] 4.147358 4.115813
#> [7,] 4.361052 4.445434
#> [8,] 4.820422 4.710468
#> [9,] 4.191424 4.652561
#> [10,] 4.094764 4.472160
#> [11,] 4.507937 4.493318
#> [12,] 4.124615 4.042316
#> [13,] 4.131012 4.780624
#> [14,] 4.310353 3.910913
#> [15,] 4.116086 3.995546
#> [16,] 4.245913 4.342984
#> TGTATTCCATCGGGTC-400.2.3 TGTCCCATCCGAGCCA-400.2.3
#> [1,] 4.140311 4.367971
#> [2,] 4.074756 4.141809
#> [3,] 4.127085 4.406479
#> [4,] 4.443933 4.307457
#> [5,] 4.426107 4.531174
#> [6,] 3.625647 4.577628
#> [7,] 4.816561 4.610024
#> [8,] 4.671650 4.855134
#> [9,] 4.100633 4.575183
#> [10,] 3.978148 4.333130
#> [11,] 4.058079 4.682152
#> [12,] 4.197240 4.477384
#> [13,] 4.420932 4.059902
#> [14,] 4.126509 4.184597
#> [15,] 3.774583 4.051956
#> [16,] 4.108683 4.477995
#> TGTTCCGGTCAGAATA-400.2.3 TGTTCCGTCAGCAACT-400.2.3
#> [1,] 4.351266 4.232479
#> [2,] 3.859968 3.981197
#> [3,] 4.121835 4.323077
#> [4,] 3.946203 3.977208
#> [5,] 4.824367 4.769231
#> [6,] 4.231013 4.101994
#> [7,] 4.251582 4.822792
#> [8,] 4.329114 4.508262
#> [9,] 4.274525 3.997721
#> [10,] 4.183544 4.040456
#> [11,] 4.400316 4.201709
#> [12,] 4.354430 3.875783
#> [13,] 4.337816 4.160114
#> [14,] 4.010285 4.437607
#> [15,] 3.905854 4.159544
#> [16,] 4.113924 4.378917
#> TTAGGACAGATCGATA-400.2.3 TTAGGCATCGCTTGTC-400.2.3
#> [1,] 4.295191 4.711911
#> [2,] 4.252902 3.491690
#> [3,] 4.394693 3.626731
#> [4,] 3.997512 4.325485
#> [5,] 4.655058 5.011773
#> [6,] 4.150912 3.732687
#> [7,] 4.293532 4.682825
#> [8,] 4.515755 4.310942
#> [9,] 4.279436 4.279778
#> [10,] 4.266998 3.858033
#> [11,] 4.300166 3.827562
#> [12,] 4.764511 4.142659
#> [13,] 3.892206 4.320637
#> [14,] 4.249585 4.369114
#> [15,] 4.338308 3.691136
#> [16,] 4.151741 3.990997
#> TTAGGCATCGGAAATA-400.2.3 TTAGTTCGTAGCGTCC-400.2.3
#> [1,] 4.386839 4.231660
#> [2,] 3.761126 3.811583
#> [3,] 4.012552 4.032432
#> [4,] 3.907189 3.842471
#> [5,] 5.509700 4.748263
#> [6,] 4.072651 3.888803
#> [7,] 5.561430 4.965251
#> [8,] 4.434386 4.491892
#> [9,] 4.112590 4.385328
#> [10,] 4.000761 3.742857
#> [11,] 4.098897 4.390734
#> [12,] 3.869152 4.185328
#> [13,] 4.232788 3.965251
#> [14,] 4.216052 4.555985
#> [15,] 3.726892 3.535135
#> [16,] 3.982883 3.885714
#> TTATGCTAGTGGTAAT-400.2.3 TTCCCAGGTAGGGACT-400.2.3
#> [1,] 4.175307 4.328717
#> [2,] 4.196419 3.679196
#> [3,] 3.931053 3.747445
#> [4,] 4.212453 4.117046
#> [5,] 5.243720 5.603363
#> [6,] 4.071619 3.919222
#> [7,] 5.059861 5.445434
#> [8,] 4.621860 4.389054
#> [9,] 4.174506 4.105506
#> [10,] 3.963121 3.818661
#> [11,] 4.106360 3.991757
#> [12,] 3.896847 3.881965
#> [13,] 4.277659 3.975602
#> [14,] 4.516301 4.391691
#> [15,] 3.798771 3.754039
#> [16,] 3.952165 3.868117
#> TTCCCAGTCGTACGGC-400.2.3 TTCGAAGAGGATGGAA-400.2.3
#> [1,] 4.236532 4.081028
#> [2,] 4.616162 4.232213
#> [3,] 4.398148 4.259881
#> [4,] 4.570707 4.004941
#> [5,] 4.441919 4.280632
#> [6,] 4.284512 4.158103
#> [7,] 4.059764 4.322134
#> [8,] 4.868687 4.814229
#> [9,] 4.459596 4.302372
#> [10,] 4.138047 4.281621
#> [11,] 4.336700 4.199605
#> [12,] 4.360269 4.682806
#> [13,] 4.490741 4.371542
#> [14,] 4.111111 4.159091
#> [15,] 3.981481 4.414032
#> [16,] 4.543771 4.588933
#> TTCGAAGGTCTGATCA-400.2.3 TTCTACAAGTGTACGG-400.2.3
#> [1,] 4.162937 4.386353
#> [2,] 4.313986 3.445828
#> [3,] 4.306294 3.854311
#> [4,] 4.153147 4.171969
#> [5,] 4.960140 4.649147
#> [6,] 3.973427 3.926694
#> [7,] 4.451748 4.604887
#> [8,] 4.501399 4.295989
#> [9,] 4.401399 4.419087
#> [10,] 4.046853 3.840941
#> [11,] 4.585315 3.838635
#> [12,] 4.669231 4.183956
#> [13,] 4.481818 4.201475
#> [14,] 4.043357 4.409866
#> [15,] 4.480420 4.181651
#> [16,] 4.438462 4.028124
#> TTCTACATCTCCGGTT-400.2.3 TTCTCAACACCGGAAA-400.2.3
#> [1,] 4.370652 4.549355
#> [2,] 4.713043 4.325533
#> [3,] 4.357609 4.539454
#> [4,] 4.314130 4.484548
#> [5,] 4.483696 4.643564
#> [6,] 4.021739 4.441944
#> [7,] 4.080435 4.658866
#> [8,] 4.653261 4.345335
#> [9,] 4.720652 4.296430
#> [10,] 4.240217 4.245725
#> [11,] 4.491304 4.459346
#> [12,] 4.182609 4.297030
#> [13,] 4.793478 4.408341
#> [14,] 4.202174 4.329733
#> [15,] 3.996739 4.265827
#> [16,] 4.618478 4.384338
#> TTCTCAACATGAACCT-400.2.3 TTCTCCTCATAGACTC-400.2.3
#> [1,] 3.841248 4.317644
#> [2,] 4.349389 4.366157
#> [3,] 4.289009 4.051112
#> [4,] 4.000000 4.145539
#> [5,] 4.343284 4.804216
#> [6,] 4.196744 3.725960
#> [7,] 4.650611 4.786890
#> [8,] 4.573270 4.589373
#> [9,] 4.643826 4.082587
#> [10,] 4.308005 4.047935
#> [11,] 4.668928 4.169506
#> [12,] 4.249661 3.993358
#> [13,] 4.276798 4.127346
#> [14,] 4.348711 4.620849
#> [15,] 4.234735 3.849264
#> [16,] 4.329715 4.207046
#> TTCTTAGAGCACACAG-400.2.3 TTCTTAGCAGCATACT-400.2.3
#> [1,] 4.516328 4.343434
#> [2,] 4.127979 4.042187
#> [3,] 4.363636 4.180036
#> [4,] 4.142983 3.837790
#> [5,] 4.240071 5.153892
#> [6,] 3.992939 4.576946
#> [7,] 4.308032 4.551396
#> [8,] 4.559576 4.742127
#> [9,] 4.289497 4.418895
#> [10,] 4.189762 4.162805
#> [11,] 4.353928 4.377897
#> [12,] 4.506620 4.572193
#> [13,] 4.537511 3.910873
#> [14,] 4.120918 3.783125
#> [15,] 4.358341 3.822935
#> [16,] 4.395410 4.691622
#> TTCTTAGCAGTAACGG-400.2.3 TTCTTAGCATTGAGCT-400.2.3
#> [1,] 4.476721 4.360011
#> [2,] 3.898926 3.608940
#> [3,] 4.046956 3.867773
#> [4,] 4.248309 4.271146
#> [5,] 4.701950 5.213597
#> [6,] 4.079586 3.994914
#> [7,] 4.504974 4.960118
#> [8,] 4.471946 4.111884
#> [9,] 4.177477 4.051660
#> [10,] 4.200955 3.830300
#> [11,] 3.973737 4.192987
#> [12,] 3.978114 3.994914
#> [13,] 4.403900 4.167024
#> [14,] 3.913251 4.191381
#> [15,] 4.171110 3.729122
#> [16,] 4.343812 4.114561
#> TTCTTAGTCCGCGGTA-400.2.3 TTGAACGAGGACCACA-400.2.3
#> [1,] 4.420138 4.703284
#> [2,] 3.966317 4.258211
#> [3,] 4.085114 4.007928
#> [4,] 4.350960 4.297848
#> [5,] 5.115538 4.396376
#> [6,] 4.135820 4.496036
#> [7,] 4.773995 4.127973
#> [8,] 4.399493 5.200453
#> [9,] 4.077870 4.459796
#> [10,] 3.939877 4.280861
#> [11,] 4.242666 3.958097
#> [12,] 4.201014 4.434881
#> [13,] 4.337197 4.494904
#> [14,] 4.299167 4.177803
#> [15,] 3.941326 4.020385
#> [16,] 4.139804 4.217441
#> TTGACTTAGACAGACC-400.2.3 TTGACTTCATATGCTG-400.2.3
#> [1,] 4.379874 4.530061
#> [2,] 3.882390 4.127607
#> [3,] 4.120755 4.479755
#> [4,] 4.181132 4.406135
#> [5,] 5.084277 4.598773
#> [6,] 4.213836 4.553374
#> [7,] 5.125786 4.373006
#> [8,] 4.500629 4.699387
#> [9,] 4.217610 4.603681
#> [10,] 3.959748 4.330061
#> [11,] 4.213208 4.422086
#> [12,] 4.096226 4.493252
#> [13,] 4.144654 4.959509
#> [14,] 4.381132 4.078528
#> [15,] 3.938365 3.892025
#> [16,] 4.110063 4.584049
#> TTGGAACGTTACCGAT-400.2.3 TTGGAACGTTTAGCTG-400.2.3
#> [1,] 4.301932 4.521930
#> [2,] 4.039050 3.941103
#> [3,] 4.043076 4.352757
#> [4,] 3.993156 4.086466
#> [5,] 4.487923 4.583333
#> [6,] 4.138889 3.994987
#> [7,] 4.743559 4.429198
#> [8,] 4.253623 4.456767
#> [9,] 4.252013 4.203008
#> [10,] 4.049517 4.045113
#> [11,] 3.975443 3.978697
#> [12,] 4.377617 4.340226
#> [13,] 4.545491 4.463659
#> [14,] 4.214573 4.057018
#> [15,] 4.382850 4.379699
#> [16,] 4.556361 4.548872
#> TTGTAGGTCACATGCA-400.2.3 TTGTAGGTCCGTTGCT-400.2.3
#> [1,] 4.526404 4.206169
#> [2,] 3.785393 4.500812
#> [3,] 4.011798 4.563312
#> [4,] 4.463483 4.417208
#> [5,] 4.646629 4.745942
#> [6,] 3.908989 4.303571
#> [7,] 4.718539 4.120942
#> [8,] 4.374157 4.657468
#> [9,] 4.171910 4.938312
#> [10,] 3.841573 4.515422
#> [11,] 4.006180 4.383929
#> [12,] 4.231461 4.347403
#> [13,] 4.335955 4.164773
#> [14,] 4.064607 4.211039
#> [15,] 4.359551 4.271916
#> [16,] 4.189888 4.675325
#> TTTACTGCATCCAACA-400.2.3 TTTACTGGTCGAAAGC-400.2.3
#> [1,] 4.331152 4.529219
#> [2,] 3.972513 3.918253
#> [3,] 3.861257 4.063033
#> [4,] 4.663613 4.194682
#> [5,] 4.180628 5.142482
#> [6,] 3.887435 3.960604
#> [7,] 4.578534 5.109652
#> [8,] 4.849476 4.272817
#> [9,] 4.653141 4.246225
#> [10,] 4.352094 4.006238
#> [11,] 4.219895 4.276756
#> [12,] 4.399215 3.959947
#> [13,] 4.704188 4.207157
#> [14,] 3.882199 4.278726
#> [15,] 3.959424 3.912344
#> [16,] 4.482984 4.188116
#> TTTATGCCAGTATAAG-400.2.3 TTTATGCTCCTCAATT-400.2.3
#> [1,] 4.390999 4.653009
#> [2,] 3.777457 4.153009
#> [3,] 4.088357 4.127401
#> [4,] 4.247316 4.361076
#> [5,] 4.714699 4.845070
#> [6,] 3.867465 4.304097
#> [7,] 4.574732 4.181818
#> [8,] 4.509496 4.488476
#> [9,] 4.355904 4.389885
#> [10,] 3.828241 3.987196
#> [11,] 4.005780 4.184379
#> [12,] 4.315855 4.039052
#> [13,] 4.098679 4.388604
#> [14,] 4.189100 4.049936
#> [15,] 4.290669 3.903969
#> [16,] 4.162675 4.632522
#> TTTCCTCGTGGAAAGA-400.2.3 TTTCCTCTCATGTCTT-400.2.3
#> [1,] 4.767597 4.231068
#> [2,] 3.618932 3.800000
#> [3,] 3.844053 3.846602
#> [4,] 4.040655 4.125566
#> [5,] 5.303398 5.432362
#> [6,] 3.978762 3.860194
#> [7,] 4.912015 4.977994
#> [8,] 4.495146 4.157282
#> [9,] 4.010316 3.900971
#> [10,] 3.678398 3.787702
#> [11,] 4.137136 4.107443
#> [12,] 3.790655 3.737864
#> [13,] 3.971481 4.180583
#> [14,] 4.137743 4.673786
#> [15,] 4.099515 3.537217
#> [16,] 4.439927 4.203236
#> TTTGCGCAGAAACGCC-400.2.3 TTTGCGCAGTTCCACA-400.2.3
#> [1,] 4.038426 3.962217
#> [2,] 4.166514 4.533165
#> [3,] 3.806953 4.205709
#> [4,] 4.053065 4.327456
#> [5,] 5.368710 4.415617
#> [6,] 3.376029 4.248531
#> [7,] 4.906679 4.261125
#> [8,] 4.477585 4.596977
#> [9,] 3.728271 4.340050
#> [10,] 3.701738 4.130982
#> [11,] 4.228728 4.387909
#> [12,] 4.023788 4.319060
#> [13,] 4.032937 4.368598
#> [14,] 4.810613 4.094878
#> [15,] 3.486734 4.090680
#> [16,] 4.039341 4.617968
#> TTTGGTTGTAAACACA-400.2.3 TTTGTCAAGTGTTAGA-400.2.3
#> [1,] 4.378289 5.221010
#> [2,] 3.561038 3.609823
#> [3,] 3.742325 3.708731
#> [4,] 4.425439 4.402456
#> [5,] 5.267178 5.427012
#> [6,] 3.952120 3.935880
#> [7,] 5.099050 5.038881
#> [8,] 4.097953 4.300819
#> [9,] 3.996345 3.898363
#> [10,] 3.875365 3.701910
#> [11,] 4.165570 3.894270
#> [12,] 3.962354 3.997954
#> [13,] 4.190058 4.292633
#> [14,] 4.198099 4.067531
#> [15,] 3.917763 4.115962
#> [16,] 3.955409 4.248977
#> TTTGTCAGTGCTAGCC-400.2.3 AAACGGGCACCAACCG-500.1.1
#> [1,] 4.667402 4.649696
#> [2,] 4.277104 4.237842
#> [3,] 4.243293 4.316869
#> [4,] 4.294377 4.306231
#> [5,] 4.559353 4.427812
#> [6,] 4.482176 4.550912
#> [7,] 4.408673 4.343465
#> [8,] 4.943403 4.601064
#> [9,] 4.650129 4.673252
#> [10,] 4.230062 4.205927
#> [11,] 4.434399 4.331307
#> [12,] 4.530320 4.366261
#> [13,] 4.292172 4.686930
#> [14,] 4.226387 4.322188
#> [15,] 4.003308 4.375380
#> [16,] 4.588019 4.786474
#> AAACGGGGTGGCCCTA-500.1.1 AAAGATGAGCTCCTTC-500.1.1
#> [1,] 4.667942 4.808734
#> [2,] 3.986228 4.108297
#> [3,] 4.117827 4.198253
#> [4,] 4.105585 4.171179
#> [5,] 4.408569 4.611354
#> [6,] 4.618975 4.141485
#> [7,] 4.290742 3.990393
#> [8,] 4.918898 5.000000
#> [9,] 4.634277 4.810480
#> [10,] 4.661056 4.310044
#> [11,] 4.541699 4.069869
#> [12,] 4.591431 4.177293
#> [13,] 4.841622 5.098690
#> [14,] 4.068860 4.246288
#> [15,] 4.146136 4.086463
#> [16,] 4.392502 4.413100
#> AAAGATGTCCTACAGA-500.1.1 AAAGCAATCGATGAGG-500.1.1
#> [1,] 4.560678 4.487223
#> [2,] 4.406780 4.509370
#> [3,] 4.115254 4.553095
#> [4,] 4.160678 4.901193
#> [5,] 4.633898 4.392391
#> [6,] 4.226441 4.222601
#> [7,] 4.166102 4.541738
#> [8,] 4.821695 4.454287
#> [9,] 4.681356 4.655877
#> [10,] 4.090847 4.169222
#> [11,] 4.227797 4.101647
#> [12,] 4.398644 4.478705
#> [13,] 4.788475 4.628620
#> [14,] 4.494915 4.480409
#> [15,] 4.130847 4.207269
#> [16,] 4.427119 4.310619
#> AAAGTAGCAGTAGAGC-500.1.1 AAATGCCAGAGTAAGG-500.1.1
#> [1,] 4.550204 4.237272
#> [2,] 4.409091 4.661864
#> [3,] 4.194030 4.560038
#> [4,] 4.128223 4.499520
#> [5,] 4.420624 4.746398
#> [6,] 4.516961 4.581172
#> [7,] 4.343962 4.451489
#> [8,] 4.981004 4.782901
#> [9,] 4.771370 4.950048
#> [10,] 4.354138 4.581172
#> [11,] 4.016961 4.365994
#> [12,] 4.313433 4.310279
#> [13,] 4.545455 4.567723
#> [14,] 4.230665 4.468780
#> [15,] 4.266621 3.931796
#> [16,] 4.569878 4.401537
#> AAATGCCGTCTTCAAG-500.1.1 AAATGCCGTTATTCTC-500.1.1
#> [1,] 4.100264 4.761115
#> [2,] 4.383905 4.469808
#> [3,] 4.186675 4.254147
#> [4,] 4.251979 4.430657
#> [5,] 4.595646 4.242203
#> [6,] 4.215699 4.463172
#> [7,] 4.058047 4.359655
#> [8,] 5.093668 4.710020
#> [9,] 4.910290 4.238885
#> [10,] 4.406332 4.766423
#> [11,] 4.341689 4.406105
#> [12,] 4.364116 4.210352
#> [13,] 4.611478 4.426012
#> [14,] 3.985488 4.209025
#> [15,] 3.850923 4.036496
#> [16,] 4.579156 4.174519
#> AACACGTTCGGAAACG-500.1.1 AACCATGGTTAAGATG-500.1.1
#> [1,] 4.556475 4.514571
#> [2,] 4.300389 4.457822
#> [3,] 4.400682 4.456288
#> [4,] 4.360273 4.271472
#> [5,] 4.363681 4.505368
#> [6,] 4.427945 4.329755
#> [7,] 4.285297 4.419479
#> [8,] 4.949854 4.770706
#> [9,] 4.962999 4.836656
#> [10,] 4.573028 4.257669
#> [11,] 4.354917 4.357362
#> [12,] 4.552580 4.505368
#> [13,] 4.511198 4.466258
#> [14,] 4.467381 4.266871
#> [15,] 4.323759 4.190951
#> [16,] 4.407498 4.631135
#> AACCATGTCTGGGCCA-500.1.1 AACCGCGAGTGAACAT-500.1.1
#> [1,] 4.315742 4.528630
#> [2,] 4.378526 4.134969
#> [3,] 4.349409 4.414110
#> [4,] 4.196542 4.348671
#> [5,] 4.471338 4.864008
#> [6,] 4.415833 4.564417
#> [7,] 4.191083 4.124744
#> [8,] 4.802548 5.141104
#> [9,] 4.687898 4.871166
#> [10,] 4.475887 3.839468
#> [11,] 4.465878 4.202454
#> [12,] 4.525023 4.605317
#> [13,] 4.664240 4.781186
#> [14,] 4.228389 4.597137
#> [15,] 4.224750 4.329243
#> [16,] 4.558690 4.162577
#> AACCGCGTCACAGGCC-500.1.1 AACTCCCAGAAGGGTA-500.1.1
#> [1,] 4.194570 4.330787
#> [2,] 3.877828 4.494712
#> [3,] 4.527149 4.304348
#> [4,] 4.343137 4.597532
#> [5,] 4.848416 4.495887
#> [6,] 4.999246 4.264982
#> [7,] 4.275264 4.352526
#> [8,] 4.990950 4.750294
#> [9,] 4.711161 4.918331
#> [10,] 4.685520 4.710928
#> [11,] 4.875566 4.326675
#> [12,] 4.210407 4.552291
#> [13,] 4.101056 4.599295
#> [14,] 4.780543 4.268508
#> [15,] 4.202112 4.424794
#> [16,] 4.569382 4.188014
#> AACTCCCGTCGCGAAA-500.1.1 AACTGGTCAAGGACTG-500.1.1
#> [1,] 4.405396 4.364929
#> [2,] 4.240612 4.520142
#> [3,] 4.305505 4.193128
#> [4,] 4.344513 4.201422
#> [5,] 4.460809 4.600711
#> [6,] 4.350711 4.223934
#> [7,] 4.384615 4.077014
#> [8,] 4.745170 5.011848
#> [9,] 4.682100 4.919431
#> [10,] 4.327743 4.327014
#> [11,] 4.378782 4.495261
#> [12,] 4.468465 4.742891
#> [13,] 4.468830 4.722749
#> [14,] 4.252279 4.189573
#> [15,] 4.410864 4.210900
#> [16,] 4.603719 4.799763
#> AACTTTCTCCCTAATT-500.1.1 AAGCCGCGTAGCTTGT-500.1.1
#> [1,] 4.282946 4.416471
#> [2,] 4.213178 3.917647
#> [3,] 4.133444 4.332941
#> [4,] 4.320044 4.397647
#> [5,] 4.415282 4.180000
#> [6,] 4.291805 4.423529
#> [7,] 4.285714 4.152941
#> [8,] 4.862126 4.898824
#> [9,] 4.733666 5.044706
#> [10,] 4.331118 4.368235
#> [11,] 4.257475 4.232941
#> [12,] 4.260797 4.530588
#> [13,] 4.735880 5.000000
#> [14,] 4.042082 4.441176
#> [15,] 3.980066 4.583529
#> [16,] 4.414175 4.805882
#> AAGCCGCGTCAACATC-500.1.1 AAGGAGCCACGCTTTC-500.1.1
#> [1,] 4.566848 4.696521
#> [2,] 4.140956 4.376758
#> [3,] 4.265578 4.254626
#> [4,] 4.152450 4.360474
#> [5,] 4.530551 4.719467
#> [6,] 4.148215 4.179867
#> [7,] 4.015124 4.216876
#> [8,] 5.089534 4.774981
#> [9,] 4.628554 4.597335
#> [10,] 4.237145 4.321984
#> [11,] 4.222021 4.223538
#> [12,] 4.569873 4.287935
#> [13,] 4.774350 4.339008
#> [14,] 4.456745 4.178386
#> [15,] 3.910466 4.124352
#> [16,] 4.344828 4.757217
#> AAGGAGCTCCGTTGTC-500.1.1 AAGTCTGCAACCGCCA-500.1.1
#> [1,] 4.319779 4.510638
#> [2,] 4.133534 4.257599
#> [3,] 4.515562 4.199848
#> [4,] 4.256526 4.417933
#> [5,] 4.730924 4.325228
#> [6,] 4.616968 4.477964
#> [7,] 4.228916 4.213526
#> [8,] 4.803715 4.658815
#> [9,] 4.728414 4.349544
#> [10,] 4.464859 4.950608
#> [11,] 4.424197 4.525076
#> [12,] 4.620984 4.261398
#> [13,] 4.100904 4.570669
#> [14,] 4.312751 4.132219
#> [15,] 4.291667 4.038754
#> [16,] 4.436245 4.221884
#> AAGTCTGCAGGGTATG-500.1.1 AATCCAGAGAGTAATC-500.1.1
#> [1,] 4.457916 4.379983
#> [2,] 4.415832 4.125530
#> [3,] 4.223447 4.196777
#> [4,] 4.624248 4.436811
#> [5,] 4.397796 4.650551
#> [6,] 4.280561 4.278202
#> [7,] 4.332665 4.094996
#> [8,] 4.751503 5.069550
#> [9,] 4.534068 4.664122
#> [10,] 4.343687 4.505513
#> [11,] 4.279559 4.248516
#> [12,] 4.481964 4.639525
#> [13,] 4.800601 4.770992
#> [14,] 4.064128 4.373198
#> [15,] 4.129259 4.158609
#> [16,] 4.668337 4.684478
#> AATCCAGGTACCGAGA-500.1.1 AATCCAGTCCTGTAGA-500.1.1
#> [1,] 4.406607 4.654867
#> [2,] 4.302414 4.182399
#> [3,] 4.219822 3.978859
#> [4,] 3.913596 4.018682
#> [5,] 4.597205 4.687316
#> [6,] 4.320203 4.283677
#> [7,] 4.199492 4.129794
#> [8,] 4.939009 4.787119
#> [9,] 4.728081 4.580138
#> [10,] 4.447268 4.345133
#> [11,] 3.853875 4.045723
#> [12,] 4.335451 4.291052
#> [13,] 3.870394 4.606686
#> [14,] 4.180432 4.147493
#> [15,] 3.940280 4.015733
#> [16,] 4.672173 4.352016
#> AATCGGTAGAGCTGCA-500.1.1 AATCGGTCAAAGAATC-500.1.1
#> [1,] 4.322841 4.160532
#> [2,] 4.258273 4.135992
#> [3,] 4.545601 4.209611
#> [4,] 4.571429 4.055726
#> [5,] 4.778854 4.442740
#> [6,] 4.451170 4.096626
#> [7,] 4.254237 4.325153
#> [8,] 5.094431 4.418712
#> [9,] 4.991929 4.423824
#> [10,] 4.163842 4.335378
#> [11,] 4.434221 4.070041
#> [12,] 4.589992 4.223415
#> [13,] 4.464084 4.512270
#> [14,] 4.081517 4.218303
#> [15,] 4.067797 3.940695
#> [16,] 4.083939 4.711656
#> AATCGGTCACTTAACG-500.1.1 AATCGGTGTCAATGTC-500.1.1
#> [1,] 4.282695 4.767123
#> [2,] 4.496697 4.638854
#> [3,] 4.387054 4.261519
#> [4,] 4.420079 4.402242
#> [5,] 4.327609 4.755915
#> [6,] 4.603699 4.346202
#> [7,] 4.262219 4.000000
#> [8,] 4.860634 4.917808
#> [9,] 4.860634 4.829390
#> [10,] 4.717305 4.306351
#> [11,] 4.108322 4.104608
#> [12,] 4.588507 4.596513
#> [13,] 4.475561 4.839352
#> [14,] 4.420740 4.239103
#> [15,] 4.456407 4.185554
#> [16,] 4.184280 4.528020
#> ACACCAACAATACGCT-500.1.1 ACACCAACACAAGTAA-500.1.1
#> [1,] 4.542750 4.393939
#> [2,] 4.232161 4.425287
#> [3,] 4.312045 4.257053
#> [4,] 4.287913 4.094044
#> [5,] 4.538173 4.485893
#> [6,] 4.471604 4.508882
#> [7,] 4.265862 4.440961
#> [8,] 4.885375 4.715778
#> [9,] 4.635115 4.852665
#> [10,] 4.343665 4.253918
#> [11,] 4.457874 4.244514
#> [12,] 4.485126 4.329154
#> [13,] 4.559601 4.639498
#> [14,] 4.529228 4.168234
#> [15,] 4.158103 4.347962
#> [16,] 4.403578 4.646813
#> ACACCAATCAAGGCTT-500.1.1 ACACCCTCATGACGGA-500.1.1
#> [1,] 4.174961 4.225646
#> [2,] 4.125194 3.856859
#> [3,] 4.135303 4.040755
#> [4,] 4.380249 4.037773
#> [5,] 4.408243 4.223658
#> [6,] 4.009331 5.079523
#> [7,] 4.367807 4.241551
#> [8,] 5.020995 5.003976
#> [9,] 4.649300 4.815109
#> [10,] 4.331260 4.248509
#> [11,] 4.472006 4.446322
#> [12,] 4.513219 4.446322
#> [13,] 4.630638 4.307157
#> [14,] 3.994557 4.845924
#> [15,] 3.966563 4.080517
#> [16,] 4.611198 4.833996
#> ACACCCTGTCACACGC-500.1.1 ACACCGGCAAGAAAGG-500.1.1
#> [1,] 4.500000 4.493701
#> [2,] 4.377931 4.296941
#> [3,] 4.267586 4.365327
#> [4,] 4.433793 4.476305
#> [5,] 4.353103 4.548890
#> [6,] 4.471724 4.470906
#> [7,] 4.228966 4.164367
#> [8,] 4.801379 4.907019
#> [9,] 4.574483 4.988002
#> [10,] 4.346897 4.402519
#> [11,] 4.277241 4.305939
#> [12,] 4.716552 4.699460
#> [13,] 4.828276 4.562687
#> [14,] 4.544828 4.032993
#> [15,] 4.299310 4.193161
#> [16,] 4.657931 4.250150
#> ACACCGGGTACTCAAC-500.1.1 ACACTGAAGCATCATC-500.1.1
#> [1,] 4.435500 4.278938
#> [2,] 4.232299 4.218306
#> [3,] 4.490786 4.326806
#> [4,] 4.212415 4.195387
#> [5,] 4.466052 4.559617
#> [6,] 4.450533 4.320279
#> [7,] 4.465567 4.373223
#> [8,] 4.801649 4.742965
#> [9,] 4.546072 4.490281
#> [10,] 4.344811 4.379460
#> [11,] 4.447624 4.424862
#> [12,] 4.511639 4.378010
#> [13,] 4.149370 4.132289
#> [14,] 4.150824 4.482158
#> [15,] 4.363725 4.251233
#> [16,] 4.444229 4.565419
#> ACAGCCGCAAACTGTC-500.1.1 ACAGCCGGTGCCTGTG-500.1.1
#> [1,] 4.283863 4.735426
#> [2,] 4.314488 4.454410
#> [3,] 4.433451 4.104634
#> [4,] 4.220259 4.212257
#> [5,] 4.248528 4.458894
#> [6,] 4.473498 4.621824
#> [7,] 4.257951 4.183857
#> [8,] 5.055359 4.745889
#> [9,] 5.203769 4.632287
#> [10,] 4.289753 4.572496
#> [11,] 4.513545 4.414051
#> [12,] 4.468787 4.325859
#> [13,] 4.106007 4.414051
#> [14,] 4.458186 3.940209
#> [15,] 4.200236 3.863976
#> [16,] 4.373380 4.233184
#> ACAGCTATCACAATGC-500.1.1 ACAGCTATCGCAAGCC-500.1.1
#> [1,] 4.089404 4.589116
#> [2,] 4.463576 4.298639
#> [3,] 4.422185 4.100680
#> [4,] 4.084437 4.248980
#> [5,] 4.345199 4.442857
#> [6,] 4.163907 4.578912
#> [7,] 4.432119 4.343537
#> [8,] 4.638245 4.955102
#> [9,] 4.331126 5.037415
#> [10,] 4.293874 4.317687
#> [11,] 4.248344 4.191156
#> [12,] 4.412252 4.443537
#> [13,] 4.314570 4.674150
#> [14,] 4.325331 4.267347
#> [15,] 4.251656 4.346259
#> [16,] 4.449503 4.531293
#> ACAGCTATCTCGGACG-500.1.1 ACATCAGAGGCATTGG-500.1.1
#> [1,] 4.735099 4.350000
#> [2,] 3.969536 4.441837
#> [3,] 4.006623 4.330612
#> [4,] 3.916556 4.309184
#> [5,] 5.067550 4.491837
#> [6,] 4.133775 4.459184
#> [7,] 4.068874 4.391837
#> [8,] 5.062252 4.596939
#> [9,] 4.741722 4.522449
#> [10,] 4.425166 4.345918
#> [11,] 4.203974 4.185714
#> [12,] 4.679470 4.395918
#> [13,] 5.196026 4.629592
#> [14,] 4.078146 4.178571
#> [15,] 3.785430 3.900000
#> [16,] 4.274172 4.857143
#> ACCAGTACACCCATGG-500.1.1 ACCAGTAGTGTCCTCT-500.1.1
#> [1,] 4.203631 4.810703
#> [2,] 3.963694 4.112620
#> [3,] 4.157064 4.282748
#> [4,] 4.194949 4.116613
#> [5,] 4.283346 4.497604
#> [6,] 5.012628 4.503195
#> [7,] 3.898185 4.092652
#> [8,] 4.859511 4.990415
#> [9,] 4.419100 4.559105
#> [10,] 4.213102 4.210863
#> [11,] 4.297553 4.259585
#> [12,] 4.255722 4.400958
#> [13,] 4.465667 4.808307
#> [14,] 4.624309 4.380192
#> [15,] 4.230466 4.181310
#> [16,] 5.022099 4.483227
#> ACCCACTAGACATAAC-500.1.1 ACCCACTAGGAATGGA-500.1.1
#> [1,] 4.661698 4.368656
#> [2,] 4.408944 4.326269
#> [3,] 4.266364 4.655884
#> [4,] 4.072586 4.444506
#> [5,] 4.755671 4.675962
#> [6,] 4.313027 4.339096
#> [7,] 4.091380 3.963748
#> [8,] 5.432275 5.272170
#> [9,] 4.898250 4.875070
#> [10,] 4.219702 4.266592
#> [11,] 4.346079 4.385945
#> [12,] 4.463383 4.327384
#> [13,] 4.913804 4.530396
#> [14,] 4.052495 4.318461
#> [15,] 4.169151 4.022867
#> [16,] 4.453014 4.627440
#> ACCCACTGTCCAACTA-500.1.1 ACCCACTGTCCGTGAC-500.1.1
#> [1,] 4.271283 4.539884
#> [2,] 4.427923 4.133793
#> [3,] 4.475596 4.078318
#> [4,] 4.382520 4.364757
#> [5,] 4.787741 4.730239
#> [6,] 4.305335 4.318709
#> [7,] 4.313280 4.304206
#> [8,] 4.776390 4.598985
#> [9,] 4.867196 4.382161
#> [10,] 4.477866 4.067803
#> [11,] 4.477866 4.093546
#> [12,] 4.570942 4.408992
#> [13,] 4.303065 4.455765
#> [14,] 4.476731 4.352429
#> [15,] 4.295119 4.159173
#> [16,] 4.610670 4.302756
#> ACCCACTGTTGGACCC-500.1.1 ACCGTAAAGAGCAATT-500.1.1
#> [1,] 4.715170 4.222078
#> [2,] 4.175439 4.307143
#> [3,] 4.331269 4.602597
#> [4,] 4.414861 4.333117
#> [5,] 4.511868 4.775325
#> [6,] 4.045408 4.483117
#> [7,] 4.132095 4.226623
#> [8,] 4.787410 5.185714
#> [9,] 5.086687 4.896104
#> [10,] 4.313725 4.315584
#> [11,] 4.001032 4.271429
#> [12,] 4.315789 4.408442
#> [13,] 4.816305 4.370130
#> [14,] 4.278638 4.623377
#> [15,] 4.130031 4.117532
#> [16,] 4.934985 4.320779
#> ACCGTAACATAGAAAC-500.1.1 ACCTTTATCTCCAGGG-500.1.1
#> [1,] 4.487106 4.029581
#> [2,] 4.433620 4.050123
#> [3,] 4.525310 4.092030
#> [4,] 4.364852 4.242399
#> [5,] 4.397326 4.187346
#> [6,] 4.522445 4.929334
#> [7,] 4.213945 4.017256
#> [8,] 4.904489 4.581758
#> [9,] 5.097421 4.505341
#> [10,] 4.480420 4.165160
#> [11,] 4.287488 3.877568
#> [12,] 4.570201 4.488907
#> [13,] 4.817574 4.405916
#> [14,] 4.251194 5.120789
#> [15,] 4.377268 4.004108
#> [16,] 4.581662 4.460970
#> ACGAGCCGTCTCTTTA-500.1.1 ACGATACCATTAGGCT-500.1.1
#> [1,] 4.608056 4.551980
#> [2,] 4.219985 4.294554
#> [3,] 4.044152 4.035479
#> [4,] 4.173509 4.103135
#> [5,] 4.364833 4.646865
#> [6,] 4.334624 4.509076
#> [7,] 4.405112 4.338284
#> [8,] 5.151046 4.974422
#> [9,] 4.773044 4.839934
#> [10,] 4.491867 4.629538
#> [11,] 4.196747 4.287129
#> [12,] 4.448490 4.240099
#> [13,] 4.491092 4.606436
#> [14,] 5.022463 4.711221
#> [15,] 4.142525 4.181518
#> [16,] 4.634392 4.642739
#> ACGATACGTGACTCAT-500.1.1 ACGATGTCACATAACC-500.1.1
#> [1,] 4.276436 4.420010
#> [2,] 4.380516 4.507008
#> [3,] 4.192340 4.614790
#> [4,] 4.171524 4.202030
#> [5,] 4.603664 4.375060
#> [6,] 4.289759 4.361044
#> [7,] 4.338884 4.017400
#> [8,] 4.756037 4.906235
#> [9,] 4.531224 4.962301
#> [10,] 4.199833 4.324795
#> [11,] 4.362198 4.403093
#> [12,] 4.801832 4.436443
#> [13,] 4.447127 4.419526
#> [14,] 4.249792 4.255679
#> [15,] 4.293089 4.379894
#> [16,] 4.758535 4.659256
#> ACGATGTCAGGTGGAT-500.1.1 ACGATGTTCTTCCTTC-500.1.1
#> [1,] 4.259980 4.262883
#> [2,] 4.232036 4.351755
#> [3,] 4.633733 4.211352
#> [4,] 4.346806 4.554892
#> [5,] 4.800898 4.458551
#> [6,] 4.319361 4.188200
#> [7,] 3.869760 4.267364
#> [8,] 5.170160 4.734130
#> [9,] 4.874750 4.630321
#> [10,] 4.287924 4.389096
#> [11,] 4.335329 4.365945
#> [12,] 4.524451 4.351008
#> [13,] 4.789421 4.592233
#> [14,] 4.183633 4.245706
#> [15,] 4.288922 3.994772
#> [16,] 4.603792 4.355489
#> ACGCCAGGTCTTGCGG-500.1.1 ACGGAGATCTTGCATT-500.1.1
#> [1,] 4.782561 4.420659
#> [2,] 4.708609 4.367066
#> [3,] 4.190949 4.129641
#> [4,] 4.364238 4.170060
#> [5,] 4.408389 4.455988
#> [6,] 4.197572 4.467665
#> [7,] 4.065121 4.346407
#> [8,] 4.944812 4.925749
#> [9,] 5.014349 4.666168
#> [10,] 4.041943 4.284132
#> [11,] 4.184327 4.278443
#> [12,] 4.537528 4.568862
#> [13,] 5.012141 4.510479
#> [14,] 4.655629 4.290719
#> [15,] 4.082781 4.277246
#> [16,] 4.769316 4.464970
#> ACGGCCATCCGAGCCA-500.1.1 ACGGCCATCGCAAGCC-500.1.1
#> [1,] 4.421209 4.159189
#> [2,] 4.060456 4.477566
#> [3,] 4.361744 4.626306
#> [4,] 4.318137 4.239705
#> [5,] 4.635282 4.690842
#> [6,] 4.473736 4.236017
#> [7,] 4.265610 4.071297
#> [8,] 5.101090 4.824216
#> [9,] 5.046581 4.808236
#> [10,] 4.228940 4.463430
#> [11,] 4.222993 4.558697
#> [12,] 4.240833 4.497849
#> [13,] 4.777007 4.443762
#> [14,] 4.508424 4.280885
#> [15,] 3.871160 4.389674
#> [16,] 4.218038 4.712354
#> ACGGGCTAGTTAACGA-500.1.1 ACGGGCTTCACGATGT-500.1.1
#> [1,] 4.527442 4.586293
#> [2,] 4.254884 4.111526
#> [3,] 3.972093 4.189408
#> [4,] 4.339535 4.298442
#> [5,] 4.580465 4.791900
#> [6,] 4.903256 4.198754
#> [7,] 4.322791 4.174455
#> [8,] 4.649302 4.836760
#> [9,] 4.451163 4.588162
#> [10,] 5.044651 4.295327
#> [11,] 4.256744 4.365109
#> [12,] 4.530233 4.368847
#> [13,] 4.664186 4.439252
#> [14,] 4.102326 3.997508
#> [15,] 4.081860 4.308411
#> [16,] 4.221395 4.370093
#> ACGGGTCGTCGACTGC-500.1.1 ACGGGTCTCAACACGT-500.1.1
#> [1,] 4.596413 4.302580
#> [2,] 4.125561 4.263487
#> [3,] 4.329276 4.079750
#> [4,] 4.418322 4.614543
#> [5,] 4.361947 4.462080
#> [6,] 4.393978 4.241595
#> [7,] 4.090967 4.333855
#> [8,] 5.119795 4.713057
#> [9,] 4.958360 4.406568
#> [10,] 4.263933 4.193120
#> [11,] 4.273543 4.203284
#> [12,] 4.628443 4.529320
#> [13,] 4.581038 4.321345
#> [14,] 4.771941 4.104769
#> [15,] 4.335682 4.238468
#> [16,] 4.450993 4.648944
#> ACGTCAAAGCACAGGT-500.1.1 ACTATCTAGAGTAATC-500.1.1
#> [1,] 4.518097 4.554230
#> [2,] 4.364012 4.351410
#> [3,] 4.298862 4.041215
#> [4,] 4.291624 4.212581
#> [5,] 4.506722 4.720174
#> [6,] 4.439504 4.116052
#> [7,] 4.201655 4.582430
#> [8,] 4.689762 4.886117
#> [9,] 4.692865 4.745119
#> [10,] 4.340228 4.336226
#> [11,] 4.361944 4.195228
#> [12,] 4.404343 4.597614
#> [13,] 4.419855 4.604121
#> [14,] 4.035160 4.312364
#> [15,] 3.982420 4.308026
#> [16,] 4.685626 4.490239
#> ACTATCTAGATGTCGG-500.1.1 ACTATCTCACGTCTCT-500.1.1
#> [1,] 4.302579 4.410342
#> [2,] 3.999008 4.271893
#> [3,] 4.484127 4.143453
#> [4,] 4.016865 4.310259
#> [5,] 4.631944 4.539616
#> [6,] 4.146825 3.942452
#> [7,] 4.346230 4.145955
#> [8,] 4.460317 4.582152
#> [9,] 4.469246 4.765638
#> [10,] 4.125992 4.229358
#> [11,] 4.055556 4.180984
#> [12,] 4.458333 4.505421
#> [13,] 4.498016 4.653044
#> [14,] 4.098214 4.296080
#> [15,] 3.895833 4.236864
#> [16,] 3.881944 4.512927
#> ACTGAGTCAGAGCCAA-500.1.1 ACTGAGTTCCCTTGTG-500.1.1
#> [1,] 4.270440 4.330205
#> [2,] 4.072956 4.271554
#> [3,] 4.638994 4.448680
#> [4,] 4.289308 4.258651
#> [5,] 4.507547 4.768915
#> [6,] 4.282390 4.076246
#> [7,] 3.711950 4.036364
#> [8,] 5.157233 5.118475
#> [9,] 5.491824 4.883284
#> [10,] 4.389308 4.053959
#> [11,] 3.993082 4.355425
#> [12,] 4.183019 4.229912
#> [13,] 4.375472 4.575953
#> [14,] 4.339623 4.424047
#> [15,] 3.964780 4.270381
#> [16,] 4.563522 4.716716
#> ACTGTCCAGGGTCTCC-500.1.1 ACTGTCCCAGCGTTCG-500.1.1
#> [1,] 4.568220 4.664319
#> [2,] 4.366057 4.100939
#> [3,] 4.260399 4.332160
#> [4,] 4.205491 4.291080
#> [5,] 4.480865 4.397887
#> [6,] 4.668053 4.442488
#> [7,] 4.236273 4.030516
#> [8,] 4.784526 4.652582
#> [9,] 4.387687 4.483568
#> [10,] 4.083195 4.063380
#> [11,] 4.075707 4.593897
#> [12,] 4.545757 4.665493
#> [13,] 4.538270 4.771127
#> [14,] 4.023295 4.218310
#> [15,] 4.207987 4.218310
#> [16,] 4.705491 4.359155
#> ACTGTCCGTCTCAACA-500.1.1 ACTGTCCTCACCCGAG-500.1.1
#> [1,] 4.308186 4.151730
#> [2,] 4.092563 4.161491
#> [3,] 4.580524 4.121562
#> [4,] 4.147673 4.213842
#> [5,] 4.711610 4.714286
#> [6,] 4.942215 4.165927
#> [7,] 4.466560 4.315883
#> [8,] 4.684858 4.985803
#> [9,] 4.716961 4.996451
#> [10,] 4.527555 4.176575
#> [11,] 4.707330 4.080745
#> [12,] 4.397539 4.470275
#> [13,] 4.084537 4.950311
#> [14,] 4.529695 4.338066
#> [15,] 4.103264 4.188997
#> [16,] 4.324238 4.384206
#> ACTGTCCTCCTGCAGG-500.1.1 ACTTACTCAAGCCGCT-500.1.1
#> [1,] 4.435703 4.403509
#> [2,] 4.419062 3.876023
#> [3,] 4.114221 4.401170
#> [4,] 4.237519 4.154386
#> [5,] 4.361573 4.761404
#> [6,] 4.633888 4.113450
#> [7,] 4.276097 4.021053
#> [8,] 5.029501 5.008187
#> [9,] 4.577912 4.732164
#> [10,] 4.314675 4.338012
#> [11,] 4.164145 4.530994
#> [12,] 4.209531 4.752047
#> [13,] 4.689864 4.872515
#> [14,] 4.557489 4.095906
#> [15,] 3.996218 4.132164
#> [16,] 4.524962 4.552047
#> ACTTTCAAGATGTGGC-500.1.1 ACTTTCACACATGGGA-500.1.1
#> [1,] 4.241512 4.364017
#> [2,] 4.075231 4.489540
#> [3,] 4.447531 4.385635
#> [4,] 4.290509 4.547420
#> [5,] 4.329090 4.393305
#> [6,] 4.205247 4.139470
#> [7,] 4.289352 4.174338
#> [8,] 5.050154 5.063459
#> [9,] 4.998071 4.965830
#> [10,] 4.389660 4.324965
#> [11,] 4.364583 4.274059
#> [12,] 4.523534 4.401674
#> [13,] 4.329090 4.223152
#> [14,] 4.286265 4.799861
#> [15,] 4.011188 4.016039
#> [16,] 4.560185 4.593445
#> ACTTTCAGTAAACGCG-500.1.1 AGAATAGTCACTTATC-500.1.1
#> [1,] 4.420870 4.374789
#> [2,] 4.051594 3.980867
#> [3,] 4.323478 4.217220
#> [4,] 4.408696 4.321891
#> [5,] 4.544348 4.743950
#> [6,] 4.597101 3.793472
#> [7,] 4.277101 4.422060
#> [8,] 5.023188 4.464266
#> [9,] 4.697391 4.251548
#> [10,] 4.314203 4.133371
#> [11,] 4.375652 3.927968
#> [12,] 4.417971 4.419246
#> [13,] 4.080580 4.159820
#> [14,] 4.441159 4.061339
#> [15,] 4.126957 4.562183
#> [16,] 4.394783 4.283061
#> AGACGTTCAGCGTCCA-500.1.1 AGACGTTGTATAGTAG-500.1.1
#> [1,] 4.172674 4.805
#> [2,] 4.207041 4.407
#> [3,] 4.325231 4.393
#> [4,] 4.523051 4.251
#> [5,] 4.718357 4.436
#> [6,] 4.503772 4.388
#> [7,] 4.002515 4.133
#> [8,] 5.093043 4.808
#> [9,] 4.897737 5.121
#> [10,] 4.322716 4.156
#> [11,] 4.187762 4.142
#> [12,] 4.686505 4.401
#> [13,] 4.691534 5.110
#> [14,] 3.976530 4.483
#> [15,] 3.994132 4.059
#> [16,] 4.484493 4.679
#> AGACGTTTCTGGTGTA-500.1.1 AGAGCGAGTTGTACAC-500.1.1
#> [1,] 4.578373 4.413254
#> [2,] 4.314484 4.816272
#> [3,] 4.383929 4.239763
#> [4,] 4.307540 4.387931
#> [5,] 4.368056 3.864763
#> [6,] 4.443452 3.975216
#> [7,] 4.354167 4.172953
#> [8,] 4.939484 4.890625
#> [9,] 4.539683 5.551185
#> [10,] 4.357143 5.261315
#> [11,] 4.183532 4.147091
#> [12,] 4.097222 4.083513
#> [13,] 4.315476 4.400323
#> [14,] 4.302579 4.399784
#> [15,] 3.878968 4.857220
#> [16,] 4.850198 4.067888
#> AGAGCGATCCTCTAGC-500.1.1 AGAGTGGCATGCCCGA-500.1.1
#> [1,] 4.646862 4.253942
#> [2,] 4.217623 4.370954
#> [3,] 4.092123 4.342739
#> [4,] 4.382510 4.453112
#> [5,] 4.632844 4.458091
#> [6,] 4.421896 4.214108
#> [7,] 4.238985 4.226556
#> [8,] 5.105474 4.962656
#> [9,] 4.901202 4.462241
#> [10,] 4.452603 4.182573
#> [11,] 4.401869 4.439004
#> [12,] 4.327770 4.609129
#> [13,] 4.758344 4.333610
#> [14,] 4.628838 4.151037
#> [15,] 4.248999 4.351037
#> [16,] 4.394526 4.512863
#> AGAGTGGTCCTAGAAC-500.1.1 AGATCTGAGTACGACG-500.1.1
#> [1,] 4.583144 4.531481
#> [2,] 4.389522 4.358025
#> [3,] 4.604784 4.112963
#> [4,] 4.379271 4.190123
#> [5,] 4.805239 4.629630
#> [6,] 4.421412 4.427160
#> [7,] 4.011390 4.182099
#> [8,] 5.283599 4.877160
#> [9,] 5.012528 4.772840
#> [10,] 4.367882 4.665432
#> [11,] 4.660592 4.440123
#> [12,] 4.359909 4.466667
#> [13,] 4.456720 4.801852
#> [14,] 4.520501 4.253086
#> [15,] 4.097950 4.029630
#> [16,] 4.194761 4.285802
#> AGATCTGTCCGTCAAA-500.1.1 AGATTGCTCCAGTAGT-500.1.1
#> [1,] 4.631926 4.550916
#> [2,] 4.187335 4.570774
#> [3,] 3.755937 4.387984
#> [4,] 4.463061 4.296843
#> [5,] 4.515831 4.127800
#> [6,] 4.767810 4.340631
#> [7,] 4.091029 4.232688
#> [8,] 5.482850 4.819246
#> [9,] 4.828496 4.827393
#> [10,] 4.199208 4.713340
#> [11,] 4.007916 4.205193
#> [12,] 4.518470 4.331976
#> [13,] 4.354881 4.684318
#> [14,] 4.283641 4.391548
#> [15,] 4.837731 4.475051
#> [16,] 4.036939 4.236762
#> AGCAGCCCAGTATGCT-500.1.1 AGCATACAGGGTTCCC-500.1.1
#> [1,] 3.942133 4.297702
#> [2,] 3.974175 4.407002
#> [3,] 3.869919 4.447622
#> [4,] 5.360115 4.325762
#> [5,] 4.839790 4.333244
#> [6,] 4.078431 4.326029
#> [7,] 3.876614 4.388295
#> [8,] 5.833572 4.862106
#> [9,] 5.794357 4.791823
#> [10,] 4.345768 4.405665
#> [11,] 4.088953 4.486905
#> [12,] 3.966523 4.574292
#> [13,] 3.892874 4.469802
#> [14,] 4.399809 4.351951
#> [15,] 4.083214 4.260823
#> [16,] 4.231946 4.704436
#> AGCGGTCTCGTGACAT-500.1.1 AGCTCTCCAAGGGTCA-500.1.1
#> [1,] 4.697506 4.777389
#> [2,] 4.095736 4.251748
#> [3,] 4.164119 4.216783
#> [4,] 4.360418 4.344988
#> [5,] 4.449718 4.687646
#> [6,] 4.535800 4.482517
#> [7,] 4.276750 4.101399
#> [8,] 5.109413 5.209790
#> [9,] 4.692679 4.883450
#> [10,] 4.650845 4.020979
#> [11,] 4.561545 4.146853
#> [12,] 4.581657 4.420746
#> [13,] 4.793242 4.902098
#> [14,] 4.277554 4.097902
#> [15,] 4.102172 3.931235
#> [16,] 4.536605 4.350816
#> AGCTTGACAGTGACAG-500.1.1 AGCTTGACATTACGAC-500.1.1
#> [1,] 4.256534 4.087783
#> [2,] 4.404402 4.527913
#> [3,] 4.349381 4.393204
#> [4,] 4.580468 4.581311
#> [5,] 4.369326 4.064725
#> [6,] 4.531637 4.245955
#> [7,] 4.180193 3.885922
#> [8,] 4.980743 5.264159
#> [9,] 4.854195 5.300566
#> [10,] 4.277854 4.235032
#> [11,] 4.268226 4.549757
#> [12,] 4.409904 4.403722
#> [13,] 4.557084 4.021845
#> [14,] 4.862448 4.292071
#> [15,] 4.191197 4.096278
#> [16,] 4.488996 4.224515
#> AGCTTGAGTCTTGATG-500.1.1 AGGCCGTTCATGCTCC-500.1.1
#> [1,] 4.576101 4.299079
#> [2,] 3.874836 4.575478
#> [3,] 3.872220 4.313962
#> [4,] 4.283908 4.163005
#> [5,] 4.650676 4.856839
#> [6,] 4.090711 4.405386
#> [7,] 4.537287 4.205528
#> [8,] 4.662015 4.902906
#> [9,] 4.548626 4.437279
#> [10,] 3.934584 4.499646
#> [11,] 4.084605 4.079376
#> [12,] 4.106847 4.401843
#> [13,] 4.534671 4.338767
#> [14,] 4.243349 4.430900
#> [15,] 3.823375 4.576896
#> [16,] 4.310510 4.666194
#> AGGGAGTCAGTAGAGC-500.1.1 AGGGATGAGCTGCCCA-500.1.1
#> [1,] 4.642992 4.545032
#> [2,] 4.387311 4.493965
#> [3,] 4.315341 4.305478
#> [4,] 3.975379 4.145775
#> [5,] 4.071023 4.492108
#> [6,] 4.201705 4.294336
#> [7,] 4.537879 4.155989
#> [8,] 5.015152 4.556175
#> [9,] 4.982008 4.462396
#> [10,] 4.390152 4.320334
#> [11,] 4.301136 4.306407
#> [12,] 4.728220 4.678737
#> [13,] 4.893939 4.268338
#> [14,] 4.069129 4.171773
#> [15,] 4.325758 4.383473
#> [16,] 4.686553 4.723305
#> AGGGATGCAAGGACTG-500.1.1 AGGGTGAGTAGATTAG-500.1.1
#> [1,] 4.499113 4.485738
#> [2,] 4.084565 4.189079
#> [3,] 4.184506 4.826406
#> [4,] 4.219988 4.526487
#> [5,] 4.688350 4.865526
#> [6,] 3.982259 4.435208
#> [7,] 4.176227 4.303993
#> [8,] 4.738616 5.103504
#> [9,] 4.204021 4.565607
#> [10,] 4.023063 4.537082
#> [11,] 3.926079 4.544417
#> [12,] 4.471319 4.621842
#> [13,] 4.371378 4.239609
#> [14,] 4.098167 4.317848
#> [15,] 4.285630 4.431948
#> [16,] 4.223536 4.012225
#> AGGTCATCAATACGCT-500.1.1 AGGTCCGAGGATATAC-500.1.1
#> [1,] 4.546304 4.411504
#> [2,] 4.395072 4.089233
#> [3,] 4.473237 4.271386
#> [4,] 4.535259 4.094395
#> [5,] 4.737468 4.869469
#> [6,] 4.491929 4.955752
#> [7,] 3.832625 4.401180
#> [8,] 5.070518 4.565634
#> [9,] 4.472387 4.702065
#> [10,] 4.208156 4.530973
#> [11,] 4.386576 4.823009
#> [12,] 4.323704 4.282448
#> [13,] 4.836024 4.087758
#> [14,] 4.732370 4.252950
#> [15,] 4.180969 4.394543
#> [16,] 4.175871 4.595133
#> AGGTCCGCAAGACGTG-500.1.1 AGTAGTCGTTATTCTC-500.1.1
#> [1,] 4.618635 4.440600
#> [2,] 3.929577 3.917330
#> [3,] 4.305525 4.110839
#> [4,] 4.226436 4.094917
#> [5,] 4.565547 4.687079
#> [6,] 4.190683 4.829761
#> [7,] 4.173348 4.094611
#> [8,] 4.825569 5.060318
#> [9,] 4.653304 4.693203
#> [10,] 4.022752 4.148806
#> [11,] 4.020585 4.509186
#> [12,] 4.477790 4.598898
#> [13,] 4.651138 4.777710
#> [14,] 4.276273 4.442743
#> [15,] 3.969664 4.053889
#> [16,] 4.404117 4.446111
#> AGTAGTCGTTGTACAC-500.1.1 AGTGAGGTCTTGGGTA-500.1.1
#> [1,] 4.430754 4.437443
#> [2,] 4.261711 4.298630
#> [3,] 4.411405 4.495890
#> [4,] 4.451120 4.048402
#> [5,] 4.588595 4.195434
#> [6,] 4.591650 3.842922
#> [7,] 4.195519 4.102283
#> [8,] 4.776986 4.512329
#> [9,] 4.948065 4.250228
#> [10,] 4.363544 4.473059
#> [11,] 4.265784 4.240183
#> [12,] 4.465377 4.336073
#> [13,] 4.830957 4.193607
#> [14,] 4.303462 4.163470
#> [15,] 4.043788 4.525114
#> [16,] 4.593686 4.368950
#> AGTGGGATCGAGCCCA-500.1.1 AGTGTCAGTAATCACC-500.1.1
#> [1,] 4.611452 4.877214
#> [2,] 4.225971 4.238489
#> [3,] 4.449898 4.323495
#> [4,] 4.097137 4.348288
#> [5,] 4.596115 5.002361
#> [6,] 4.455010 4.299882
#> [7,] 4.258691 3.757969
#> [8,] 4.729039 5.088548
#> [9,] 4.911043 4.526564
#> [10,] 4.408998 4.537190
#> [11,] 4.273006 4.335301
#> [12,] 4.419223 4.395514
#> [13,] 4.210634 5.072019
#> [14,] 4.370143 4.145218
#> [15,] 4.197342 4.044864
#> [16,] 4.706544 4.134593
#> ATAAGAGAGATGCCAG-500.1.1 ATAAGAGCAATGTTGC-500.1.1
#> [1,] 4.267820 4.524440
#> [2,] 4.557093 4.450102
#> [3,] 4.368166 3.951120
#> [4,] 4.602768 4.328921
#> [5,] 4.219377 4.793279
#> [6,] 4.431834 4.370672
#> [7,] 4.413149 4.121181
#> [8,] 4.651211 4.751527
#> [9,] 4.398616 4.516293
#> [10,] 4.461592 4.493890
#> [11,] 4.435986 4.149695
#> [12,] 4.395848 4.537678
#> [13,] 4.070588 4.541752
#> [14,] 4.710727 4.271894
#> [15,] 4.438754 4.350305
#> [16,] 4.125260 4.788187
#> ATAAGAGGTCTAAAGA-500.1.1 ATAGACCGTGTAACGG-500.1.1
#> [1,] 4.176471 4.599219
#> [2,] 4.332657 4.112500
#> [3,] 4.494929 4.289063
#> [4,] 4.186613 4.150781
#> [5,] 4.203854 4.402344
#> [6,] 4.111562 4.614844
#> [7,] 4.518256 4.487500
#> [8,] 5.166329 4.946094
#> [9,] 4.712982 4.780469
#> [10,] 4.460446 4.369531
#> [11,] 4.370183 4.082812
#> [12,] 4.958418 4.403906
#> [13,] 4.844828 4.534375
#> [14,] 4.470588 4.193750
#> [15,] 4.365112 4.096094
#> [16,] 4.635903 4.678906
#> ATCACGAAGAGACTTA-500.1.1 ATCACGAGTAAATGTG-500.1.1
#> [1,] 4.672808 4.484590
#> [2,] 4.151805 4.451148
#> [3,] 4.244657 4.188197
#> [4,] 4.394989 4.484590
#> [5,] 4.522476 4.376393
#> [6,] 4.219602 4.409180
#> [7,] 4.200442 4.458361
#> [8,] 4.921887 4.979016
#> [9,] 4.854090 4.488525
#> [10,] 4.273397 4.480656
#> [11,] 4.182019 4.436721
#> [12,] 4.616802 4.241967
#> [13,] 4.831982 4.517377
#> [14,] 4.431835 4.198689
#> [15,] 4.088430 4.187541
#> [16,] 4.427413 4.453115
#> ATCATGGCAGGACCCT-500.1.1 ATCCGAACAATTGCTG-500.1.1
#> [1,] 4.281040 4.219570
#> [2,] 4.352349 4.713604
#> [3,] 4.272651 4.096659
#> [4,] 4.309564 4.051313
#> [5,] 4.323826 4.184964
#> [6,] 4.140940 4.121718
#> [7,] 4.245805 4.278043
#> [8,] 4.772651 4.918854
#> [9,] 4.501678 5.150358
#> [10,] 4.153523 4.737470
#> [11,] 4.355705 4.220764
#> [12,] 4.238255 4.736277
#> [13,] 4.645973 4.433174
#> [14,] 3.904362 4.372315
#> [15,] 4.109060 4.423628
#> [16,] 4.332215 4.547733
#> ATCCGAAGTGTGCGTC-500.1.1 ATCGAGTAGAGGTTAT-500.1.1
#> [1,] 4.425478 4.330120
#> [2,] 4.628025 4.600964
#> [3,] 4.478981 4.241928
#> [4,] 4.468790 4.543614
#> [5,] 4.486624 4.314217
#> [6,] 4.421656 4.149880
#> [7,] 4.091720 4.479036
#> [8,] 5.634395 4.836145
#> [9,] 4.543949 4.558072
#> [10,] 3.859873 4.550361
#> [11,] 4.245860 4.401446
#> [12,] 4.385987 4.677590
#> [13,] 4.173248 4.464096
#> [14,] 4.335032 4.187470
#> [15,] 4.016561 4.396145
#> [16,] 4.061146 4.325783
#> ATCGAGTAGGCTATCT-500.1.1 ATCGAGTGTAGAGCTG-500.1.1
#> [1,] 4.199195 4.446172
#> [2,] 4.536553 4.325359
#> [3,] 4.196512 4.476077
#> [4,] 4.404427 4.346890
#> [5,] 4.242790 4.531100
#> [6,] 4.370892 4.464115
#> [7,] 4.162978 4.187799
#> [8,] 4.855131 5.257177
#> [9,] 5.073776 4.421053
#> [10,] 4.892019 4.025120
#> [11,] 4.213950 4.772727
#> [12,] 4.315895 4.281100
#> [13,] 4.435278 3.964115
#> [14,] 4.610999 4.484450
#> [15,] 4.586854 4.050239
#> [16,] 4.367539 4.052632
#> ATCTACTAGAACTCGG-500.1.1 ATCTACTGTAAACGCG-500.1.1
#> [1,] 4.384017 4.296209
#> [2,] 4.012023 4.188784
#> [3,] 4.115983 4.053712
#> [4,] 4.606082 4.011848
#> [5,] 4.415842 4.315166
#> [6,] 4.496464 4.493681
#> [7,] 4.333098 4.296998
#> [8,] 4.772984 4.803318
#> [9,] 5.161245 4.670616
#> [10,] 4.384724 3.895735
#> [11,] 4.201556 4.233807
#> [12,] 4.388260 4.620063
#> [13,] 4.669731 4.433649
#> [14,] 4.824611 4.098736
#> [15,] 4.128713 4.137441
#> [16,] 4.099010 4.667457
#> ATCTACTTCTCGCTTG-500.1.1 ATCTGCCAGCAGCCTC-500.1.1
#> [1,] 4.144595 4.198788
#> [2,] 4.671622 4.317576
#> [3,] 4.340541 4.367273
#> [4,] 4.195946 4.185455
#> [5,] 4.279730 4.249697
#> [6,] 4.132432 4.572121
#> [7,] 4.120270 4.464242
#> [8,] 4.767568 4.755152
#> [9,] 4.933784 4.578182
#> [10,] 4.947297 4.503030
#> [11,] 4.108108 4.276364
#> [12,] 4.401351 4.768485
#> [13,] 4.502703 4.654545
#> [14,] 4.424324 4.344242
#> [15,] 4.717568 4.495758
#> [16,] 4.594595 4.429091
#> ATCTGCCAGGATGGTC-500.1.1 ATCTGCCTCCCGACTT-500.1.1
#> [1,] 4.356654 4.241415
#> [2,] 4.364481 4.429761
#> [3,] 4.405088 4.552549
#> [4,] 4.642857 4.035380
#> [5,] 4.363014 4.111342
#> [6,] 4.168787 4.206035
#> [7,] 4.430039 4.308012
#> [8,] 4.982877 4.902185
#> [9,] 4.692759 4.711759
#> [10,] 4.488258 4.301769
#> [11,] 4.405088 4.268470
#> [12,] 4.686399 4.315297
#> [13,] 4.428571 4.147763
#> [14,] 4.413405 4.166493
#> [15,] 4.579256 4.483871
#> [16,] 4.498532 4.765869
#> ATGCGATCAATCCGAT-500.1.1 ATGCGATGTAATCGTC-500.1.1
#> [1,] 4.663198 4.329305
#> [2,] 4.074740 4.140987
#> [3,] 3.990539 4.357503
#> [4,] 4.538316 4.353474
#> [5,] 4.592242 4.402820
#> [6,] 4.883633 4.314199
#> [7,] 4.248817 4.075529
#> [8,] 4.804163 5.077543
#> [9,] 4.405866 4.880161
#> [10,] 4.367077 4.280967
#> [11,] 4.291391 4.062437
#> [12,] 4.692526 4.545821
#> [13,] 4.600757 4.379658
#> [14,] 4.760643 4.741188
#> [15,] 3.825922 4.379658
#> [16,] 4.730369 4.377644
#> ATGCGATTCAAGAAGT-500.1.1 ATGCGATTCTTGACGA-500.1.1
#> [1,] 4.421419 4.725051
#> [2,] 4.162726 4.316701
#> [3,] 4.579972 4.374745
#> [4,] 4.512517 4.433809
#> [5,] 4.454798 4.576375
#> [6,] 4.413769 4.577393
#> [7,] 4.276773 4.218941
#> [8,] 4.948540 5.045825
#> [9,] 4.970097 4.624236
#> [10,] 4.411683 4.312627
#> [11,] 4.266342 4.260692
#> [12,] 4.475661 4.675153
#> [13,] 4.614743 4.675153
#> [14,] 4.289986 4.124236
#> [15,] 4.168985 4.308554
#> [16,] 4.326147 4.355397
#> ATGGGAGTCATCGCTC-500.1.1 ATGGGAGTCCGATATG-500.1.1
#> [1,] 4.553368 4.729683
#> [2,] 4.022798 5.020530
#> [3,] 4.071503 3.948674
#> [4,] 4.313990 4.516681
#> [5,] 4.333679 4.384089
#> [6,] 4.523316 4.798973
#> [7,] 4.115026 4.296835
#> [8,] 4.873575 4.911035
#> [9,] 4.699482 4.061591
#> [10,] 4.250777 4.907613
#> [11,] 3.903627 4.439692
#> [12,] 4.376166 4.551754
#> [13,] 4.793782 4.357571
#> [14,] 4.106736 4.309666
#> [15,] 4.217617 3.978614
#> [16,] 4.693264 4.314799
#> ATTACTCTCGTGGTCG-500.1.1 ATTATCCCATGTAAGA-500.1.1
#> [1,] 3.992922 4.278071
#> [2,] 4.205258 4.438583
#> [3,] 4.442872 4.354936
#> [4,] 4.277048 4.088922
#> [5,] 4.597573 4.504898
#> [6,] 5.208291 4.449887
#> [7,] 4.282103 4.104748
#> [8,] 4.610718 5.085154
#> [9,] 4.748231 4.770912
#> [10,] 4.542973 4.275810
#> [11,] 5.053589 4.574228
#> [12,] 4.402427 4.531274
#> [13,] 3.748231 4.397136
#> [14,] 4.510617 4.215524
#> [15,] 4.625885 4.227581
#> [16,] 4.539939 4.762622
#> ATTATCCTCCACTGGG-500.1.1 ATTCTACGTGTAACGG-500.1.1
#> [1,] 4.375071 4.448465
#> [2,] 4.737621 4.392544
#> [3,] 4.589641 4.380482
#> [4,] 4.533295 4.089912
#> [5,] 4.449630 4.657895
#> [6,] 4.129767 4.392544
#> [7,] 4.628344 4.307018
#> [8,] 4.872510 4.974781
#> [9,] 4.398406 4.813596
#> [10,] 4.336938 4.307018
#> [11,] 4.311895 4.405702
#> [12,] 4.593056 4.463816
#> [13,] 4.312464 4.940789
#> [14,] 4.410359 4.198465
#> [15,] 4.665908 3.973684
#> [16,] 4.655094 4.855263
#> ATTGGACCAGTCAGAG-500.1.1 ATTGGTGGTTTCGCTC-500.1.1
#> [1,] 4.479330 4.561455
#> [2,] 4.248045 5.171091
#> [3,] 4.004469 3.718781
#> [4,] 4.419553 4.423795
#> [5,] 4.300000 4.296952
#> [6,] 4.184358 4.946903
#> [7,] 4.239665 3.962635
#> [8,] 5.034637 4.906588
#> [9,] 4.694413 4.091445
#> [10,] 4.302235 4.640118
#> [11,] 4.465922 4.315634
#> [12,] 4.386034 4.504425
#> [13,] 4.559218 4.508358
#> [14,] 4.817318 4.430678
#> [15,] 4.128492 3.880039
#> [16,] 4.520670 4.115044
#> ATTGGTGTCACCTTAT-500.1.1 ATTGGTGTCGGACAAG-500.1.1
#> [1,] 4.231828 4.462810
#> [2,] 4.226872 3.957300
#> [3,] 4.722467 3.900826
#> [4,] 4.452093 4.019284
#> [5,] 4.625000 4.506887
#> [6,] 4.302863 4.209366
#> [7,] 4.069383 4.263085
#> [8,] 5.060022 4.724518
#> [9,] 5.002203 4.768595
#> [10,] 4.174009 4.075758
#> [11,] 4.177863 3.860882
#> [12,] 4.478524 4.212121
#> [13,] 4.500551 4.975207
#> [14,] 4.366189 4.563361
#> [15,] 4.109031 4.154270
#> [16,] 4.553414 4.544077
#> ATTTCTGAGAACAATC-500.1.1 CAACCAAGTAGAAAGG-500.1.1
#> [1,] 4.262917 4.397612
#> [2,] 4.506213 4.529844
#> [3,] 4.487247 4.406795
#> [4,] 4.322433 4.320478
#> [5,] 4.342708 4.328742
#> [6,] 4.294310 4.467401
#> [7,] 4.409418 4.167126
#> [8,] 4.762590 4.320478
#> [9,] 4.974493 4.700643
#> [10,] 4.436887 4.341598
#> [11,] 4.047744 4.328742
#> [12,] 4.528450 4.380165
#> [13,] 4.592544 4.264463
#> [14,] 4.638980 4.606979
#> [15,] 4.052976 4.182736
#> [16,] 4.367560 4.258035
#> CAACCTCCATGGTCAT-500.1.1 CAACCTCGTTAAGATG-500.1.1
#> [1,] 4.482893 4.521232
#> [2,] 4.281525 4.560366
#> [3,] 4.205279 3.955870
#> [4,] 4.219941 4.338052
#> [5,] 4.657869 4.444629
#> [6,] 4.283480 4.623647
#> [7,] 4.301075 4.084929
#> [8,] 4.871945 4.811823
#> [9,] 4.794721 4.422981
#> [10,] 4.076246 4.820983
#> [11,] 4.347019 4.367194
#> [12,] 4.561095 4.421316
#> [13,] 4.854350 4.823480
#> [14,] 4.355816 4.153206
#> [15,] 4.132942 4.094088
#> [16,] 4.450635 4.398834
#> CAACTAGAGTCGAGTG-500.1.1 CAACTAGTCGCCCTTA-500.1.1
#> [1,] 4.378549 4.529226
#> [2,] 4.240536 5.173776
#> [3,] 4.170347 4.556872
#> [4,] 4.328864 4.120853
#> [5,] 4.508675 4.378357
#> [6,] 4.171924 4.716430
#> [7,] 4.275237 4.357820
#> [8,] 4.914038 4.643760
#> [9,] 4.668770 3.581359
#> [10,] 4.135647 4.247235
#> [11,] 4.420347 5.078989
#> [12,] 4.332019 4.818325
#> [13,] 4.463722 3.854660
#> [14,] 4.435331 4.053712
#> [15,] 3.981073 3.925750
#> [16,] 4.581230 3.822275
#> CAAGAAATCTAACTCT-500.1.1 CAAGATCAGTACGTAA-500.1.1
#> [1,] 4.266979 4.374177
#> [2,] 4.037471 4.291831
#> [3,] 4.070258 4.330040
#> [4,] 4.062061 4.588933
#> [5,] 4.861827 4.368906
#> [6,] 4.488290 4.595520
#> [7,] 4.151054 4.154809
#> [8,] 4.918033 5.185112
#> [9,] 4.655738 4.868906
#> [10,] 4.298595 4.482872
#> [11,] 4.337237 4.346509
#> [12,] 4.539813 4.584321
#> [13,] 4.358314 4.518445
#> [14,] 4.028103 4.737813
#> [15,] 4.292740 4.374177
#> [16,] 4.530445 4.469038
#> CAAGATCCAGCCACCA-500.1.1 CAAGATCGTCCATCCT-500.1.1
#> [1,] 4.437927 4.700149
#> [2,] 4.379366 5.654762
#> [3,] 4.291002 4.156994
#> [4,] 4.344438 4.159970
#> [5,] 4.434510 3.885417
#> [6,] 4.374620 4.909970
#> [7,] 4.408884 4.531994
#> [8,] 4.869875 4.620536
#> [9,] 4.694286 4.005208
#> [10,] 4.388193 4.363839
#> [11,] 4.337984 4.349702
#> [12,] 4.491838 4.869048
#> [13,] 4.422172 4.525298
#> [14,] 4.252752 4.412946
#> [15,] 4.217065 3.838542
#> [16,] 4.624051 4.015625
#> CAAGGCCAGAGTGAGA-500.1.1 CAAGGCCAGGTGATAT-500.1.1
#> [1,] 4.453125 4.461285
#> [2,] 4.177951 4.497529
#> [3,] 4.335069 4.111203
#> [4,] 4.385417 4.481878
#> [5,] 4.423611 4.523064
#> [6,] 4.582465 4.567545
#> [7,] 4.059896 4.295717
#> [8,] 5.104167 4.847611
#> [9,] 4.414062 4.745470
#> [10,] 4.313368 4.548600
#> [11,] 3.991319 4.512356
#> [12,] 4.307292 4.445634
#> [13,] 4.821181 4.437397
#> [14,] 4.458333 4.124382
#> [15,] 4.253472 3.977759
#> [16,] 4.815104 4.284185
#> CAAGGCCCACGAGGTA-500.1.1 CACAAACCACTCAGGC-500.1.1
#> [1,] 4.424746 4.604478
#> [2,] 4.217913 4.195096
#> [3,] 4.288089 4.195096
#> [4,] 4.298246 4.149254
#> [5,] 4.239151 4.776119
#> [6,] 4.575254 4.471215
#> [7,] 4.795937 4.392324
#> [8,] 4.970452 4.897655
#> [9,] 4.832872 4.921109
#> [10,] 4.572484 4.347548
#> [11,] 4.274238 4.269723
#> [12,] 4.641736 4.510661
#> [13,] 4.071099 5.205757
#> [14,] 4.649123 4.294243
#> [15,] 4.025854 3.900853
#> [16,] 4.361958 4.526652
#> CACACCTCAAAGTGCG-500.1.1 CACACCTCAGATCTGT-500.1.1
#> [1,] 4.406147 4.502798
#> [2,] 4.264544 4.203837
#> [3,] 4.425906 4.253397
#> [4,] 4.195390 4.346922
#> [5,] 4.670692 4.222222
#> [6,] 4.309550 4.215028
#> [7,] 4.145993 4.482814
#> [8,] 4.768386 4.796163
#> [9,] 4.672887 4.727418
#> [10,] 4.574094 4.174261
#> [11,] 4.270033 4.251799
#> [12,] 4.567508 4.546763
#> [13,] 4.537870 4.422062
#> [14,] 4.844127 4.314149
#> [15,] 4.480790 4.028777
#> [16,] 4.391877 4.284572
#> CACACCTGTACCCAAT-500.1.1 CACACTCGTCATATGC-500.1.1
#> [1,] 4.894201 4.338534
#> [2,] 4.520855 4.433177
#> [3,] 4.252289 4.597504
#> [4,] 4.121058 4.299532
#> [5,] 4.712106 4.347374
#> [6,] 4.166836 4.277171
#> [7,] 4.157681 4.081123
#> [8,] 4.924720 4.911076
#> [9,] 4.612411 5.111284
#> [10,] 3.995931 4.241810
#> [11,] 4.254323 4.215289
#> [12,] 4.193286 4.355694
#> [13,] 4.614446 4.467499
#> [14,] 4.145473 4.389496
#> [15,] 4.107833 4.293292
#> [16,] 4.739573 4.605304
#> CACAGTATCGTAGGTT-500.1.1 CACATAGAGACTAGGC-500.1.1
#> [1,] 4.545384 4.377086
#> [2,] 4.350659 4.316388
#> [3,] 4.381691 4.253414
#> [4,] 4.506594 4.425645
#> [5,] 4.477114 4.200303
#> [6,] 4.122576 3.916540
#> [7,] 3.985260 4.307284
#> [8,] 5.169123 4.611533
#> [9,] 5.151280 4.720789
#> [10,] 4.401086 4.374052
#> [11,] 3.909232 4.066009
#> [12,] 4.323507 4.560698
#> [13,] 4.540729 4.515933
#> [14,] 4.564003 3.904401
#> [15,] 4.114042 4.150986
#> [16,] 4.056633 4.505311
#> CACATAGGTCAGTGGA-500.1.1 CACATAGGTGGGTCAA-500.1.1
#> [1,] 4.658745 4.749692
#> [2,] 3.991445 4.246609
#> [3,] 3.874525 4.182491
#> [4,] 4.133080 4.154131
#> [5,] 4.795627 5.131936
#> [6,] 4.033270 4.186190
#> [7,] 3.808935 3.948212
#> [8,] 5.112167 5.162762
#> [9,] 4.844106 4.438964
#> [10,] 3.968631 4.219482
#> [11,] 3.973384 4.108508
#> [12,] 4.660646 4.450062
#> [13,] 5.340304 5.447596
#> [14,] 4.139734 4.017263
#> [15,] 3.799430 4.217016
#> [16,] 4.398289 4.537608
#> CACATTTGTTTACTCT-500.1.1 CACCACTGTAACGTTC-500.1.1
#> [1,] 3.921123 4.509219
#> [2,] 5.278075 4.334504
#> [3,] 4.899733 4.297629
#> [4,] 5.025401 4.332748
#> [5,] 4.728610 4.867428
#> [6,] 3.586898 4.510975
#> [7,] 4.290107 4.299385
#> [8,] 5.217914 4.876207
#> [9,] 3.925134 4.573310
#> [10,] 4.070856 4.565408
#> [11,] 4.422460 4.280070
#> [12,] 4.868984 4.429324
#> [13,] 3.574866 4.882353
#> [14,] 4.574866 4.510975
#> [15,] 3.556150 4.275680
#> [16,] 4.185829 4.289728
#> CACCACTTCTTGCATT-500.1.1 CACCAGGAGTGGAGAA-500.1.1
#> [1,] 4.405510 4.540317
#> [2,] 4.193330 4.389601
#> [3,] 4.341228 4.300678
#> [4,] 4.143064 4.197438
#> [5,] 4.636539 4.608139
#> [6,] 4.816336 4.330068
#> [7,] 4.273562 4.371515
#> [8,] 4.812470 4.943482
#> [9,] 4.667472 4.914092
#> [10,] 4.480425 4.583271
#> [11,] 4.521025 4.456669
#> [12,] 4.424843 4.346647
#> [13,] 4.310778 4.592313
#> [14,] 4.525375 4.266767
#> [15,] 4.283229 4.311228
#> [16,] 4.329145 4.503391
#> CACCTTGGTTCCAACA-500.1.1 CACCTTGTCAAGATCC-500.1.1
#> [1,] 4.526358 4.723549
#> [2,] 4.174920 4.089875
#> [3,] 4.361022 4.531286
#> [4,] 4.287540 4.054608
#> [5,] 4.833866 4.483504
#> [6,] 4.348243 4.007964
#> [7,] 4.301118 4.236633
#> [8,] 4.996805 5.014790
#> [9,] 4.950479 4.868032
#> [10,] 4.052716 4.310580
#> [11,] 4.307508 3.992036
#> [12,] 4.637380 4.269625
#> [13,] 4.921725 5.154721
#> [14,] 4.130192 4.087600
#> [15,] 4.171725 3.896473
#> [16,] 4.563898 4.538111
#> CAGAATCCAGTATCTG-500.1.1 CAGAATCTCGCGTAGC-500.1.1
#> [1,] 4.611596 4.428571
#> [2,] 4.133416 4.004926
#> [3,] 4.384040 3.831281
#> [4,] 4.489401 4.375616
#> [5,] 4.863466 4.278325
#> [6,] 4.400873 4.113300
#> [7,] 4.170200 4.501232
#> [8,] 5.159601 5.097291
#> [9,] 4.850998 5.093596
#> [10,] 4.384663 4.600985
#> [11,] 4.331047 3.986453
#> [12,] 4.640898 4.288177
#> [13,] 4.959476 4.618227
#> [14,] 4.207606 4.408867
#> [15,] 4.043641 4.619458
#> [16,] 4.301746 4.352217
#> CAGATCACAGGACCCT-500.1.1 CAGATCAGTCGACTAT-500.1.1
#> [1,] 4.257210 4.382313
#> [2,] 4.265783 4.174150
#> [3,] 4.320343 4.036735
#> [4,] 4.608730 4.117007
#> [5,] 4.343726 4.632653
#> [6,] 4.825409 4.545578
#> [7,] 4.375682 4.103401
#> [8,] 5.072486 4.657143
#> [9,] 4.623539 4.870748
#> [10,] 4.820733 4.219048
#> [11,] 4.528449 4.420408
#> [12,] 4.294622 4.843537
#> [13,] 4.328137 4.783673
#> [14,] 4.538581 4.284354
#> [15,] 4.335931 3.760544
#> [16,] 4.346064 4.673469
#> CAGCATAAGCGCTCCA-500.1.1 CAGCCGATCCACGAAT-500.1.1
#> [1,] 4.250891 4.344096
#> [2,] 4.081934 4.317343
#> [3,] 4.449873 4.070111
#> [4,] 4.308906 4.037823
#> [5,] 4.766921 4.531365
#> [6,] 4.801018 4.246310
#> [7,] 4.409669 4.137454
#> [8,] 4.724682 4.839483
#> [9,] 4.694148 4.654982
#> [10,] 4.493639 4.117159
#> [11,] 4.625445 4.304428
#> [12,] 4.318575 4.485240
#> [13,] 4.161832 4.714022
#> [14,] 4.535878 4.135609
#> [15,] 4.089059 4.253690
#> [16,] 4.498728 4.950185
#> CAGCGACAGGGCACTA-500.1.1 CAGCTAACAAGCCGTC-500.1.1
#> [1,] 4.711066 4.291878
#> [2,] 4.289617 4.444162
#> [3,] 4.221995 4.390017
#> [4,] 4.267077 4.275804
#> [5,] 4.331284 4.552453
#> [6,] 4.618169 4.616751
#> [7,] 4.428962 4.293570
#> [8,] 4.745219 4.619289
#> [9,] 4.631148 4.763113
#> [10,] 4.569672 4.129442
#> [11,] 4.148907 4.308799
#> [12,] 4.300546 4.186125
#> [13,] 4.540984 4.305415
#> [14,] 4.418033 4.437394
#> [15,] 4.560792 4.105753
#> [16,] 4.383880 4.538071
#> CAGCTGGCATTGGCGC-500.1.1 CAGGTGCAGACAGAGA-500.1.1
#> [1,] 4.535714 4.291237
#> [2,] 4.108014 4.487113
#> [3,] 4.145470 4.617698
#> [4,] 4.141986 4.352234
#> [5,] 4.494774 4.334192
#> [6,] 4.604530 4.437285
#> [7,] 4.376307 4.239691
#> [8,] 4.825784 4.934708
#> [9,] 4.466028 4.913230
#> [10,] 4.358014 4.268041
#> [11,] 3.990418 4.340206
#> [12,] 4.641115 4.324742
#> [13,] 4.829268 4.930412
#> [14,] 4.211672 4.415808
#> [15,] 4.203833 4.302405
#> [16,] 4.499129 4.396048
#> CAGTAACGTACAGACG-500.1.1 CAGTAACGTTCACCTC-500.1.1
#> [1,] 4.825342 4.513001
#> [2,] 4.322603 3.794691
#> [3,] 4.059589 3.971289
#> [4,] 4.637671 4.330986
#> [5,] 4.380137 4.674431
#> [6,] 4.588356 4.267064
#> [7,] 4.302740 4.277356
#> [8,] 4.844521 4.459372
#> [9,] 4.369863 4.331528
#> [10,] 5.215753 4.247021
#> [11,] 4.292466 4.113218
#> [12,] 4.654795 4.043337
#> [13,] 4.854795 4.381365
#> [14,] 4.536986 4.293608
#> [15,] 4.134932 3.933911
#> [16,] 4.613014 4.131094
#> CAGTCCTAGGACGAAA-500.1.1 CAGTCCTGTCCCTTGT-500.1.1
#> [1,] 4.547872 4.223478
#> [2,] 4.557181 4.265217
#> [3,] 4.304521 4.395652
#> [4,] 4.148936 4.546087
#> [5,] 4.428191 4.300870
#> [6,] 4.384309 4.473043
#> [7,] 4.244681 4.299130
#> [8,] 4.537234 4.804348
#> [9,] 4.714096 5.221739
#> [10,] 4.273936 4.911304
#> [11,] 4.134309 4.432174
#> [12,] 4.644947 4.254783
#> [13,] 4.313830 4.325217
#> [14,] 4.191489 4.953043
#> [15,] 4.263298 4.466957
#> [16,] 4.579787 4.126087
#> CATATTCAGTAGGTGC-500.1.1 CATATTCAGTGTCCCG-500.1.1
#> [1,] 4.317152 4.206349
#> [2,] 4.305286 3.922751
#> [3,] 4.183387 4.055026
#> [4,] 3.995685 4.108995
#> [5,] 4.716289 4.546032
#> [6,] 4.412082 4.773545
#> [7,] 4.267530 4.266667
#> [8,] 4.740022 4.891005
#> [9,] 4.908306 4.461376
#> [10,] 4.486516 4.065608
#> [11,] 4.324703 4.157672
#> [12,] 4.526429 4.437037
#> [13,] 4.646170 4.847619
#> [14,] 4.532902 4.811640
#> [15,] 4.394822 3.956614
#> [16,] 4.702265 4.874074
#> CATATTCTCGGTGTTA-500.1.1 CATCAAGAGGGTTCCC-500.1.1
#> [1,] 4.597538 4.519068
#> [2,] 4.454545 4.247881
#> [3,] 4.155303 4.045904
#> [4,] 4.232955 4.189266
#> [5,] 4.246212 4.422316
#> [6,] 4.309659 4.522599
#> [7,] 4.203598 4.353814
#> [8,] 4.691288 4.934322
#> [9,] 4.403409 4.538842
#> [10,] 4.660985 4.663136
#> [11,] 4.494318 4.534605
#> [12,] 4.472538 4.451977
#> [13,] 4.550189 4.616525
#> [14,] 4.082386 4.482345
#> [15,] 4.128788 4.506356
#> [16,] 4.296402 4.851695
#> CATCAAGAGTCGCCGT-500.1.1 CATCAAGAGTGTCCAT-500.1.1
#> [1,] 4.252216 4.650899
#> [2,] 4.298952 4.144749
#> [3,] 4.617244 4.088931
#> [4,] 4.487510 4.454115
#> [5,] 4.824335 4.611164
#> [6,] 4.431104 4.277200
#> [7,] 4.312651 3.845790
#> [8,] 5.253022 5.178808
#> [9,] 4.568090 4.448439
#> [10,] 4.429492 4.219489
#> [11,] 4.667204 4.023652
#> [12,] 4.614021 4.315989
#> [13,] 4.101531 4.894040
#> [14,] 4.487510 4.022706
#> [15,] 4.236100 4.025544
#> [16,] 4.256245 4.322611
#> CATCAAGTCCACGTTC-500.1.1 CATCCACGTTGGAGGT-500.1.1
#> [1,] 4.226216 4.487716
#> [2,] 4.458069 4.121929
#> [3,] 4.384073 4.375796
#> [4,] 4.417195 4.383076
#> [5,] 4.618041 4.672429
#> [6,] 4.121917 4.454049
#> [7,] 4.011980 4.080983
#> [8,] 4.804087 4.821656
#> [9,] 4.722340 4.905369
#> [10,] 4.362227 3.870792
#> [11,] 4.235377 4.104641
#> [12,] 4.365046 4.308462
#> [13,] 4.445384 5.120109
#> [14,] 4.201550 4.458599
#> [15,] 4.255109 4.173794
#> [16,] 4.642001 4.602366
#> CATCCACTCTATCGCC-500.1.1 CATCGAAGTAAGTGTA-500.1.1
#> [1,] 4.320098 4.317215
#> [2,] 3.997862 4.456802
#> [3,] 4.390959 4.317537
#> [4,] 4.446854 4.675693
#> [5,] 4.440134 4.604126
#> [6,] 4.274588 4.581883
#> [7,] 3.732132 4.346551
#> [8,] 5.168296 5.129594
#> [9,] 5.373549 4.606705
#> [10,] 4.566585 4.346228
#> [11,] 4.319487 4.466473
#> [12,] 4.122175 4.676338
#> [13,] 4.315211 4.457124
#> [14,] 4.385156 4.512573
#> [15,] 3.928528 4.479046
#> [16,] 4.094380 4.445519
#> CATCGAATCTTTAGTC-500.1.1 CATCGGGAGACCCACC-500.1.1
#> [1,] 4.388013 4.396063
#> [2,] 4.089229 4.166107
#> [3,] 4.101397 4.386462
#> [4,] 4.182965 4.305809
#> [5,] 4.468229 4.446952
#> [6,] 4.284813 4.180029
#> [7,] 4.318161 4.246759
#> [8,] 4.692654 4.826692
#> [9,] 4.684543 4.526644
#> [10,] 4.165390 4.216035
#> [11,] 4.477693 4.103217
#> [12,] 4.276701 4.518963
#> [13,] 4.830104 4.534325
#> [14,] 3.976566 4.496880
#> [15,] 3.699865 4.200672
#> [16,] 4.230284 4.061450
#> CATCGGGCATCGTCGG-500.1.1 CATCGGGTCTTCGAGA-500.1.1
#> [1,] 4.795868 4.669643
#> [2,] 4.979339 4.158163
#> [3,] 3.786777 4.173469
#> [4,] 4.371074 4.108418
#> [5,] 4.601653 4.673469
#> [6,] 4.677686 4.159439
#> [7,] 4.241322 4.197704
#> [8,] 4.962810 5.522959
#> [9,] 4.055372 4.852041
#> [10,] 4.833884 4.406888
#> [11,] 4.204959 4.294643
#> [12,] 4.347934 4.385204
#> [13,] 4.698347 5.128827
#> [14,] 4.359504 4.016582
#> [15,] 3.918182 3.866071
#> [16,] 4.295868 4.358418
#> CATGACACACCCAGTG-500.1.1 CATTATCGTAAGGGCT-500.1.1
#> [1,] 4.490793 4.503734
#> [2,] 4.222380 4.332780
#> [3,] 4.077904 4.232365
#> [4,] 4.324363 4.027386
#> [5,] 4.573654 4.370954
#> [6,] 4.295326 4.814108
#> [7,] 4.265581 4.299585
#> [8,] 5.089235 4.653942
#> [9,] 4.865439 4.476349
#> [10,] 4.564448 4.237344
#> [11,] 4.576487 4.185892
#> [12,] 4.618272 4.354357
#> [13,] 4.599858 4.590041
#> [14,] 4.604816 4.243154
#> [15,] 4.281161 4.021577
#> [16,] 4.439802 4.885477
#> CATTATCTCGTACGGC-500.1.1 CATTCGCGTCTTCGTC-500.1.1
#> [1,] 4.414302 4.163693
#> [2,] 4.459705 4.065943
#> [3,] 4.441544 4.193949
#> [4,] 4.111237 4.605896
#> [5,] 4.482406 4.176881
#> [6,] 4.303065 4.373933
#> [7,] 4.213394 4.124127
#> [8,] 5.044268 4.916990
#> [9,] 4.559591 4.983708
#> [10,] 4.473326 4.626067
#> [11,] 4.332577 4.415050
#> [12,] 4.593644 4.442203
#> [13,] 4.305335 4.189294
#> [14,] 4.104427 5.028704
#> [15,] 4.281498 4.434445
#> [16,] 4.488082 4.330489
#> CCACCTAAGAGGTACC-500.1.1 CCACGGAAGATCCTGT-500.1.1
#> [1,] 4.798287 4.309266
#> [2,] 4.193925 4.385078
#> [3,] 4.269470 4.385680
#> [4,] 4.262461 4.449458
#> [5,] 4.171340 4.876053
#> [6,] 4.274922 4.462094
#> [7,] 4.136293 4.225632
#> [8,] 5.192368 4.969314
#> [9,] 5.015576 5.009627
#> [10,] 4.245327 4.090253
#> [11,] 4.110592 4.388688
#> [12,] 4.512461 4.676895
#> [13,] 4.768692 4.462696
#> [14,] 4.503115 4.195548
#> [15,] 4.052181 4.234657
#> [16,] 4.524143 4.638387
#> CCACGGAAGCGATCCC-500.1.1 CCACGGAAGGACAGCT-500.1.1
#> [1,] 4.194567 4.135635
#> [2,] 4.197504 4.331073
#> [3,] 4.322320 4.424784
#> [4,] 4.175477 4.419852
#> [5,] 4.473568 4.579531
#> [6,] 4.314978 4.325524
#> [7,] 4.267988 3.927867
#> [8,] 4.640235 4.919236
#> [9,] 4.637298 4.829840
#> [10,] 4.500734 4.206535
#> [11,] 4.426579 4.233662
#> [12,] 4.962555 4.166461
#> [13,] 4.570485 4.561652
#> [14,] 4.151982 4.207768
#> [15,] 4.540382 4.294081
#> [16,] 4.414831 4.757090
#> CCACTACAGCTGTCTA-500.1.1 CCACTACCAAGGTGTG-500.1.1
#> [1,] 4.559152 4.351724
#> [2,] 4.661830 4.026207
#> [3,] 3.955357 4.262069
#> [4,] 4.583705 4.202759
#> [5,] 4.516741 4.609655
#> [6,] 4.606027 4.532414
#> [7,] 4.015625 4.310345
#> [8,] 5.378348 4.503448
#> [9,] 4.581473 4.416552
#> [10,] 4.157366 4.477241
#> [11,] 4.122768 4.044138
#> [12,] 4.430804 4.448276
#> [13,] 4.783482 4.419310
#> [14,] 4.400670 4.182069
#> [15,] 3.976563 4.046897
#> [16,] 4.287946 4.342069
#> CCACTACCACGAAGCA-500.1.1 CCAGCGAAGGGTCGAT-500.1.1
#> [1,] 4.373324 4.427928
#> [2,] 4.521448 4.843468
#> [3,] 4.132038 4.637387
#> [4,] 4.332440 4.427928
#> [5,] 4.513405 4.647523
#> [6,] 4.195040 4.472973
#> [7,] 4.145442 4.239865
#> [8,] 4.898123 5.313063
#> [9,] 4.770777 4.769144
#> [10,] 4.038874 4.206081
#> [11,] 4.258043 4.306306
#> [12,] 4.511394 4.816441
#> [13,] 4.764745 4.292793
#> [14,] 4.022118 4.780405
#> [15,] 4.220509 4.154279
#> [16,] 4.611260 4.242117
#> CCAGCGACATCAGTAC-500.1.1 CCATTCGCAGCCTTTC-500.1.1
#> [1,] 4.368648 4.253440
#> [2,] 4.109779 4.250777
#> [3,] 4.089645 4.409676
#> [4,] 4.425695 4.223258
#> [5,] 4.751678 4.546826
#> [6,] 4.182167 4.373724
#> [7,] 4.546021 4.035952
#> [8,] 4.765101 5.169996
#> [9,] 4.213806 5.163338
#> [10,] 4.118888 4.303151
#> [11,] 4.071908 4.333333
#> [12,] 4.298178 4.479805
#> [13,] 4.569511 4.583666
#> [14,] 4.133269 4.367066
#> [15,] 4.212848 4.220151
#> [16,] 4.135187 4.447403
#> CCATTCGGTCGACTAT-500.1.1 CCATTCGTCGGGAGTA-500.1.1
#> [1,] 4.295455 4.260773
#> [2,] 4.244091 4.716022
#> [3,] 4.499545 4.140884
#> [4,] 4.519545 4.386740
#> [5,] 4.616364 4.239779
#> [6,] 4.563636 4.215470
#> [7,] 4.087273 4.392818
#> [8,] 5.032273 4.986740
#> [9,] 4.584545 4.737569
#> [10,] 4.617273 4.472376
#> [11,] 4.672727 4.329282
#> [12,] 4.524545 4.817680
#> [13,] 4.209545 4.614365
#> [14,] 4.607727 4.282873
#> [15,] 4.482727 4.327072
#> [16,] 4.309091 4.346961
#> CCATTCGTCTTATCTG-500.1.1 CCCAATCCAGACGCCT-500.1.1
#> [1,] 4.567231 4.618167
#> [2,] 4.138023 4.533221
#> [3,] 4.073909 4.319596
#> [4,] 4.321460 4.324643
#> [5,] 4.591273 4.740959
#> [6,] 4.473731 4.511354
#> [7,] 4.189671 4.269134
#> [8,] 4.969724 4.873003
#> [9,] 4.678540 4.806560
#> [10,] 4.524488 4.319596
#> [11,] 4.203028 4.276703
#> [12,] 4.494212 4.379310
#> [13,] 4.358860 4.418839
#> [14,] 4.830810 4.238015
#> [15,] 4.365093 4.243061
#> [16,] 4.218166 4.643398
#> CCCAGTTGTCGGCACT-500.1.1 CCCATACAGCTGATAA-500.1.1
#> [1,] 4.266436 4.290525
#> [2,] 4.298443 3.925460
#> [3,] 4.095156 4.110013
#> [4,] 4.145329 4.359228
#> [5,] 4.412630 5.016614
#> [6,] 4.455882 4.032330
#> [7,] 4.110727 4.433767
#> [8,] 4.675606 4.738662
#> [9,] 4.634948 4.445442
#> [10,] 4.216263 4.123035
#> [11,] 4.162630 4.045352
#> [12,] 4.244810 4.086215
#> [13,] 4.546713 4.718455
#> [14,] 4.067474 4.055231
#> [15,] 4.042388 3.915132
#> [16,] 4.655709 4.390211
#> CCCATACTCTTGACGA-500.1.1 CCGGTAGAGGTGCACA-500.1.1
#> [1,] 4.469543 4.357606
#> [2,] 4.366328 4.449171
#> [3,] 4.480541 4.512617
#> [4,] 4.628596 4.675559
#> [5,] 4.450931 4.576063
#> [6,] 4.460237 4.635184
#> [7,] 3.947547 4.395097
#> [8,] 4.854484 4.877433
#> [9,] 4.789340 4.865177
#> [10,] 3.924704 4.367700
#> [11,] 3.875635 4.358327
#> [12,] 4.328257 4.852199
#> [13,] 4.790186 4.175919
#> [14,] 3.768190 4.333814
#> [15,] 4.016074 4.354001
#> [16,] 4.563452 4.469358
#> CCGGTAGCATGGGAAC-500.1.1 CCGGTAGGTTACGCGC-500.1.1
#> [1,] 4.108594 4.389717
#> [2,] 4.387742 4.540238
#> [3,] 4.456362 4.557377
#> [4,] 4.804797 4.371088
#> [5,] 4.246502 4.277943
#> [6,] 4.094604 4.537258
#> [7,] 4.143238 4.135618
#> [8,] 4.766156 5.242921
#> [9,] 5.065290 4.973920
#> [10,] 4.540973 4.575261
#> [11,] 4.262492 4.382265
#> [12,] 4.664890 4.658718
#> [13,] 4.281812 4.702683
#> [14,] 4.555630 4.559613
#> [15,] 4.274484 4.459016
#> [16,] 4.378414 4.647541
#> CCGTACTCATACGCTA-500.1.1 CCGTTCAAGGATGGTC-500.1.1
#> [1,] 4.436588 4.213644
#> [2,] 4.497755 4.192491
#> [3,] 4.544893 4.296140
#> [4,] 4.805275 4.289794
#> [5,] 4.240741 4.728186
#> [6,] 4.540404 4.520360
#> [7,] 4.367565 4.050238
#> [8,] 4.742424 5.391856
#> [9,] 4.812570 5.048652
#> [10,] 4.475870 4.478583
#> [11,] 4.329966 4.269699
#> [12,] 4.669473 4.358012
#> [13,] 4.286756 4.598625
#> [14,] 4.531425 4.515071
#> [15,] 4.318743 4.102591
#> [16,] 4.413580 4.487044
#> CCGTTCACATGATCCA-500.1.1 CCGTTCAGTCGACTAT-500.1.1
#> [1,] 4.405263 4.363108
#> [2,] 4.086842 4.160148
#> [3,] 4.156140 4.440803
#> [4,] 4.178947 4.140592
#> [5,] 4.335088 4.625264
#> [6,] 4.332456 4.372093
#> [7,] 4.356140 4.265856
#> [8,] 4.979825 5.235201
#> [9,] 4.721930 5.018499
#> [10,] 4.226316 4.181818
#> [11,] 4.477193 4.498414
#> [12,] 4.191228 4.391649
#> [13,] 4.669298 4.382664
#> [14,] 4.096491 4.213531
#> [15,] 4.003509 4.137949
#> [16,] 4.635088 4.548097
#> CCTACACAGTGCGATG-500.1.1 CCTACACCAAGCCGTC-500.1.1
#> [1,] 4.115385 4.281879
#> [2,] 4.610509 4.250240
#> [3,] 4.160347 4.274209
#> [4,] 4.332611 3.953979
#> [5,] 4.009209 4.236817
#> [6,] 4.283315 4.145733
#> [7,] 3.964789 4.251198
#> [8,] 4.750271 4.880153
#> [9,] 5.265980 4.813998
#> [10,] 4.959913 4.402685
#> [11,] 4.154930 3.878236
#> [12,] 4.117010 4.785235
#> [13,] 4.547129 4.904123
#> [14,] 4.463705 4.028763
#> [15,] 4.781148 4.307766
#> [16,] 4.148971 4.459252
#> CCTACACCACGGCTAC-500.1.1 CCTACCACAGCTGTGC-500.1.1
#> [1,] 4.511191 4.292135
#> [2,] 4.384116 4.305145
#> [3,] 4.488809 4.468953
#> [4,] 4.427437 4.773507
#> [5,] 4.057040 4.500296
#> [6,] 4.412996 4.326434
#> [7,] 4.092419 4.398581
#> [8,] 4.959567 4.525724
#> [9,] 5.189170 5.164400
#> [10,] 4.539350 4.314015
#> [11,] 4.166065 4.189829
#> [12,] 4.521300 4.531047
#> [13,] 4.466426 4.266706
#> [14,] 4.427437 4.528090
#> [15,] 3.855596 4.370787
#> [16,] 4.522744 4.303371
#> CCTACCACATAGTAAG-500.1.1 CCTAGCTAGCTAGGCA-500.1.1
#> [1,] 4.544204 4.477447
#> [2,] 4.970530 4.176170
#> [3,] 4.013752 4.439149
#> [4,] 4.388998 4.332766
#> [5,] 4.374263 4.655319
#> [6,] 5.012770 4.449362
#> [7,] 4.372299 4.373617
#> [8,] 4.252456 5.062979
#> [9,] 4.222986 4.609362
#> [10,] 4.760314 4.254468
#> [11,] 4.095285 4.493617
#> [12,] 4.625737 4.333617
#> [13,] 4.538310 4.827234
#> [14,] 4.339882 4.242553
#> [15,] 3.882122 4.020426
#> [16,] 4.366405 4.247660
#> CCTATTAAGCTAAACA-500.1.1 CCTATTAGTTTGTGTG-500.1.1
#> [1,] 4.500865 4.438889
#> [2,] 4.095156 4.594444
#> [3,] 4.149654 4.142857
#> [4,] 4.254325 4.752381
#> [5,] 4.673875 4.492857
#> [6,] 4.346021 4.189683
#> [7,] 3.963668 4.519841
#> [8,] 5.442907 4.792063
#> [9,] 5.124567 4.471429
#> [10,] 4.173010 4.551587
#> [11,] 4.247405 4.444444
#> [12,] 4.858131 4.683333
#> [13,] 4.755190 4.360317
#> [14,] 4.381488 4.342857
#> [15,] 3.864187 4.540476
#> [16,] 4.458478 4.455556
#> CCTATTATCGCCATAA-500.1.1 CCTCAGTGTCTAGAGG-500.1.1
#> [1,] 4.212188 4.511097
#> [2,] 4.168869 4.204961
#> [3,] 4.560940 4.264360
#> [4,] 4.893539 4.663185
#> [5,] 4.844347 4.422324
#> [6,] 4.128488 4.144909
#> [7,] 3.826725 4.501958
#> [8,] 5.317181 4.626632
#> [9,] 5.472834 4.611619
#> [10,] 4.742291 4.501305
#> [11,] 4.140235 4.416449
#> [12,] 4.226872 4.702350
#> [13,] 4.093979 4.913185
#> [14,] 4.468429 4.028721
#> [15,] 4.107195 4.140992
#> [16,] 4.135830 4.363577
#> CCTTACGGTCGATTGT-500.1.1 CCTTCCCGTACTCTCC-500.1.1
#> [1,] 4.619632 4.634529
#> [2,] 4.088227 4.284753
#> [3,] 4.138183 3.904709
#> [4,] 4.326030 4.137892
#> [5,] 4.681274 4.732063
#> [6,] 4.225533 4.511211
#> [7,] 4.262635 4.077354
#> [8,] 4.631902 5.081839
#> [9,] 4.189015 5.000000
#> [10,] 4.188431 4.207399
#> [11,] 4.101081 4.402466
#> [12,] 4.366053 4.577354
#> [13,] 4.471516 4.554933
#> [14,] 4.096991 4.282511
#> [15,] 4.102834 4.047085
#> [16,] 4.305872 4.552691
#> CCTTCGAAGAGTAAGG-500.1.1 CCTTCGATCATCATTC-500.1.1
#> [1,] 4.351515 4.176590
#> [2,] 4.345455 4.279465
#> [3,] 4.486580 4.359255
#> [4,] 4.695238 4.295666
#> [5,] 4.765368 4.396517
#> [6,] 4.671861 4.410693
#> [7,] 4.633766 3.955853
#> [8,] 5.077922 5.266100
#> [9,] 4.862338 5.217902
#> [10,] 4.561905 4.255974
#> [11,] 4.140260 4.403807
#> [12,] 4.845022 4.395302
#> [13,] 4.346320 4.237748
#> [14,] 4.527273 4.496557
#> [15,] 4.058874 4.142163
#> [16,] 4.120346 4.441474
#> CCTTTCTCATGGATGG-500.1.1 CCTTTCTGTGGTCCGT-500.1.1
#> [1,] 4.113274 4.644346
#> [2,] 3.838053 4.254580
#> [3,] 3.824779 4.130764
#> [4,] 4.068142 4.151611
#> [5,] 4.124779 4.560328
#> [6,] 5.162832 4.126974
#> [7,] 4.250442 4.165509
#> [8,] 5.143363 4.620341
#> [9,] 4.608850 4.490208
#> [10,] 4.400885 4.121920
#> [11,] 3.935398 4.197726
#> [12,] 4.154867 4.301958
#> [13,] 4.594690 4.639292
#> [14,] 4.979646 3.924826
#> [15,] 3.965487 4.284902
#> [16,] 4.747788 4.487682
#> CGAACATAGCTACCTA-500.1.1 CGAACATAGTGTGGCA-500.1.1
#> [1,] 4.520408 4.387981
#> [2,] 4.184807 4.511669
#> [3,] 3.995465 4.378646
#> [4,] 4.241497 4.374562
#> [5,] 4.484127 4.316803
#> [6,] 4.393424 4.311552
#> [7,] 4.208617 4.474912
#> [8,] 4.543084 4.928238
#> [9,] 4.812925 4.684947
#> [10,] 4.405896 4.426488
#> [11,] 3.823129 4.167445
#> [12,] 4.755102 4.455659
#> [13,] 4.301587 4.666278
#> [14,] 4.195011 4.439323
#> [15,] 4.273243 4.546674
#> [16,] 4.553288 4.558343
#> CGACCTTAGTGAACAT-500.1.1 CGACCTTTCGAATCCA-500.1.1
#> [1,] 4.516529 4.435028
#> [2,] 4.311295 4.298493
#> [3,] 4.298898 4.329567
#> [4,] 4.629477 4.327684
#> [5,] 4.419421 4.548964
#> [6,] 4.312672 4.233522
#> [7,] 4.679063 4.329567
#> [8,] 4.750689 4.625235
#> [9,] 4.714187 4.864407
#> [10,] 4.338843 4.417137
#> [11,] 4.300275 4.129944
#> [12,] 4.529614 4.414313
#> [13,] 4.812672 4.568738
#> [14,] 4.196281 3.980226
#> [15,] 4.240358 4.062147
#> [16,] 4.604683 4.778719
#> CGACTTCGTTCACGGC-500.1.1 CGACTTCTCACAGTAC-500.1.1
#> [1,] 4.774289 4.035452
#> [2,] 4.208538 4.749164
#> [3,] 4.350834 4.472910
#> [4,] 4.441119 4.307023
#> [5,] 4.554956 4.269565
#> [6,] 4.280177 4.400000
#> [7,] 4.214426 4.148495
#> [8,] 4.882237 4.937124
#> [9,] 4.510304 5.105017
#> [10,] 4.756624 4.886957
#> [11,] 4.335623 4.375920
#> [12,] 4.220805 4.273579
#> [13,] 4.832679 4.521070
#> [14,] 4.006379 4.438127
#> [15,] 4.016192 4.859532
#> [16,] 4.246811 4.206020
#> CGACTTCTCCTAGGGC-500.1.1 CGAGAAGCACGCGAAA-500.1.1
#> [1,] 4.576632 4.325453
#> [2,] 4.340893 4.092987
#> [3,] 4.274914 4.610717
#> [4,] 4.362887 4.625690
#> [5,] 4.090034 4.735225
#> [6,] 4.567010 4.587864
#> [7,] 4.447423 4.382979
#> [8,] 5.073540 5.147360
#> [9,] 4.569759 4.750985
#> [10,] 4.696907 4.463357
#> [11,] 4.345017 4.559496
#> [12,] 4.519588 4.728132
#> [13,] 4.653608 4.360126
#> [14,] 4.193814 4.284476
#> [15,] 4.421306 4.094563
#> [16,] 4.570447 4.426320
#> CGAGCACAGAGTGAGA-500.1.1 CGAGCACGTCGCATCG-500.1.1
#> [1,] 4.304160 4.425445
#> [2,] 4.659103 4.115595
#> [3,] 4.350621 4.677839
#> [4,] 4.528903 4.419289
#> [5,] 4.500810 4.649111
#> [6,] 4.524041 4.731874
#> [7,] 4.370070 4.186731
#> [8,] 4.984333 4.801642
#> [9,] 4.665586 4.634063
#> [10,] 4.473258 4.479480
#> [11,] 4.555375 4.561560
#> [12,] 4.701243 4.515048
#> [13,] 4.336575 4.089603
#> [14,] 4.576445 4.755130
#> [15,] 4.422474 4.367989
#> [16,] 4.509454 4.339945
#> CGAGCACGTGAAGGCT-500.1.1 CGATCGGTCAAGAAGT-500.1.1
#> [1,] 4.615265 4.390543
#> [2,] 4.510125 4.510508
#> [3,] 4.186137 4.241681
#> [4,] 4.244548 4.056918
#> [5,] 4.605140 4.586690
#> [6,] 4.556854 4.281961
#> [7,] 4.102804 4.082312
#> [8,] 4.718847 4.595447
#> [9,] 4.602804 4.781086
#> [10,] 4.674455 4.453590
#> [11,] 4.561526 4.051664
#> [12,] 4.345794 4.444834
#> [13,] 4.492212 4.543783
#> [14,] 4.069315 4.222417
#> [15,] 3.906542 4.203152
#> [16,] 4.190810 4.747811
#> CGATCGGTCACATAGC-500.1.1 CGATGGCCAATCCGAT-500.1.1
#> [1,] 4.507663 4.459544
#> [2,] 4.298851 4.698133
#> [3,] 4.716475 4.282158
#> [4,] 4.138570 4.170124
#> [5,] 4.480843 4.691909
#> [6,] 4.337165 4.325726
#> [7,] 3.966156 3.977178
#> [8,] 4.950830 4.643154
#> [9,] 5.086207 4.767635
#> [10,] 4.103448 4.284232
#> [11,] 4.290549 4.100622
#> [12,] 4.549808 4.614108
#> [13,] 4.558748 4.440871
#> [14,] 4.134100 4.266598
#> [15,] 4.126437 4.377593
#> [16,] 4.597063 4.691909
#> CGATTGAAGCGTAGTG-500.1.1 CGATTGACAATAGAGT-500.1.1
#> [1,] 4.380282 4.669075
#> [2,] 4.459932 4.083815
#> [3,] 4.483730 4.291908
#> [4,] 4.305488 4.540462
#> [5,] 4.682856 4.710260
#> [6,] 4.361826 4.195087
#> [7,] 4.047596 4.244942
#> [8,] 4.902380 4.865607
#> [9,] 5.018941 4.430636
#> [10,] 4.318116 4.010838
#> [11,] 4.421564 4.089595
#> [12,] 4.361340 4.216763
#> [13,] 4.733851 4.638728
#> [14,] 4.162700 3.872832
#> [15,] 4.026712 3.958092
#> [16,] 4.635746 4.461705
#> CGATTGATCTTCTGGC-500.1.1 CGCGGTAGTTTAGGAA-500.1.1
#> [1,] 4.547718 4.361111
#> [2,] 4.152490 4.162222
#> [3,] 4.104772 4.230000
#> [4,] 4.139523 4.143333
#> [5,] 4.603734 4.462222
#> [6,] 4.565353 4.723333
#> [7,] 4.039419 4.106667
#> [8,] 5.006743 4.797778
#> [9,] 4.577801 4.714444
#> [10,] 4.311203 4.223333
#> [11,] 4.237033 3.847778
#> [12,] 4.289419 4.474444
#> [13,] 4.716805 4.456667
#> [14,] 4.519191 4.338889
#> [15,] 4.203320 4.347778
#> [16,] 4.596992 4.761111
#> CGCGGTATCTCCTATA-500.1.1 CGCTATCTCCTATGTT-500.1.1
#> [1,] 4.515971 4.239621
#> [2,] 4.368550 4.288420
#> [3,] 4.116298 4.278223
#> [4,] 4.306306 4.359068
#> [5,] 4.452088 4.252731
#> [6,] 4.168714 4.056810
#> [7,] 4.308763 4.300801
#> [8,] 4.773137 4.762564
#> [9,] 5.076167 4.504734
#> [10,] 4.810811 4.436271
#> [11,] 4.146601 4.207575
#> [12,] 4.517609 4.348143
#> [13,] 4.706798 4.698471
#> [14,] 4.841933 4.001457
#> [15,] 4.049140 4.372178
#> [16,] 4.682228 4.615441
#> CGCTGGAAGGCATGTG-500.1.1 CGCTTCAAGATCGATA-500.1.1
#> [1,] 4.626364 4.758065
#> [2,] 4.124545 4.133995
#> [3,] 3.940000 4.315136
#> [4,] 4.476364 3.918114
#> [5,] 4.480000 4.863524
#> [6,] 4.375455 4.152605
#> [7,] 4.263636 4.101737
#> [8,] 5.034545 4.946650
#> [9,] 4.950000 4.478908
#> [10,] 4.555455 4.222084
#> [11,] 4.551818 4.119107
#> [12,] 4.305455 4.462779
#> [13,] 4.537273 5.199752
#> [14,] 4.170000 4.101737
#> [15,] 4.028182 4.198511
#> [16,] 4.290909 4.419355
#> CGCTTCAAGTGGGTTG-500.1.1 CGCTTCAGTATAGGTA-500.1.1
#> [1,] 4.627032 4.144691
#> [2,] 4.343028 4.135356
#> [3,] 4.018820 4.229872
#> [4,] 4.326775 4.213536
#> [5,] 4.520958 4.302217
#> [6,] 4.424294 4.431739
#> [7,] 4.278015 4.178530
#> [8,] 5.139435 4.707118
#> [9,] 4.600513 4.660443
#> [10,] 4.378101 4.424737
#> [11,] 4.334474 3.829638
#> [12,] 4.307956 4.448075
#> [13,] 4.756202 4.952159
#> [14,] 4.189906 4.149358
#> [15,] 4.194183 3.750292
#> [16,] 4.488452 4.703617
#> CGGACGTAGTGGAGTC-500.1.1 CGGACGTCAATGAAAC-500.1.1
#> [1,] 4.573770 4.448545
#> [2,] 4.522475 4.258359
#> [3,] 4.228979 4.174989
#> [4,] 4.310947 4.206687
#> [5,] 4.565838 4.539731
#> [6,] 4.291909 3.980026
#> [7,] 4.087784 4.296570
#> [8,] 5.122158 4.788537
#> [9,] 4.563194 4.426835
#> [10,] 4.193548 3.825011
#> [11,] 4.126917 4.339557
#> [12,] 4.274458 4.364307
#> [13,] 4.879958 4.679114
#> [14,] 4.415124 4.127225
#> [15,] 4.112110 3.867564
#> [16,] 4.495505 4.571863
#> CGGCTAGCAATGGATA-500.1.1 CGGGTCACACATGACT-500.1.1
#> [1,] 4.436996 4.954764
#> [2,] 4.417339 4.211742
#> [3,] 4.139113 4.385948
#> [4,] 4.321069 4.422522
#> [5,] 4.570060 4.621752
#> [6,] 4.512097 4.362849
#> [7,] 4.092238 3.911453
#> [8,] 5.051915 5.135707
#> [9,] 5.048891 4.375361
#> [10,] 4.208165 4.458133
#> [11,] 4.590726 3.972089
#> [12,] 4.401210 4.327238
#> [13,] 4.543347 4.937440
#> [14,] 4.557460 4.293551
#> [15,] 4.161794 4.165544
#> [16,] 4.482359 4.130895
#> CGGGTCACATCAGTAC-500.1.1 CGGTTAATCACGAAGG-500.1.1
#> [1,] 4.694862 4.279202
#> [2,] 4.369960 4.547009
#> [3,] 4.211067 4.441026
#> [4,] 4.086957 4.439886
#> [5,] 4.675889 4.523647
#> [6,] 4.457708 4.313390
#> [7,] 4.250593 4.653561
#> [8,] 5.132016 4.811396
#> [9,] 4.786561 4.737322
#> [10,] 4.361265 4.531624
#> [11,] 4.138340 4.346439
#> [12,] 4.330435 4.640456
#> [13,] 5.062451 4.569231
#> [14,] 4.350198 4.361254
#> [15,] 4.210277 4.609117
#> [16,] 4.368379 4.440456
#> CGTAGCGAGGCTCAGA-500.1.1 CGTAGCGGTAACGTTC-500.1.1
#> [1,] 4.703180 4.402760
#> [2,] 4.739399 4.464241
#> [3,] 4.094523 4.649937
#> [4,] 4.303004 4.400251
#> [5,] 4.524735 4.529486
#> [6,] 4.545936 4.053952
#> [7,] 4.139576 4.380176
#> [8,] 4.946113 4.818068
#> [9,] 4.192580 4.496863
#> [10,] 4.799470 4.560853
#> [11,] 4.220848 4.414053
#> [12,] 4.379859 4.987453
#> [13,] 4.500883 4.131744
#> [14,] 4.273852 4.101631
#> [15,] 3.933746 4.432873
#> [16,] 4.258834 4.299875
#> CGTCACTGTTCATGGT-500.1.1 CGTCAGGAGTCGATAA-500.1.1
#> [1,] 4.460602 4.683113
#> [2,] 4.142550 4.357887
#> [3,] 4.290115 4.150799
#> [4,] 4.490688 4.208478
#> [5,] 4.378223 4.262682
#> [6,] 4.627507 4.291174
#> [7,] 4.300860 4.439194
#> [8,] 5.011461 4.811675
#> [9,] 4.775072 4.640028
#> [10,] 4.270057 4.699792
#> [11,] 4.401862 4.275191
#> [12,] 4.719198 4.373176
#> [13,] 4.321633 4.722029
#> [14,] 4.563037 4.559416
#> [15,] 3.941977 4.457262
#> [16,] 4.290115 4.526060
#> CGTCAGGTCATGCATG-500.1.1 CGTCTACGTAGTAGTA-500.1.1
#> [1,] 4.418958 4.416667
#> [2,] 4.104197 4.393805
#> [3,] 4.195369 4.328171
#> [4,] 4.461650 4.436578
#> [5,] 4.273517 4.318584
#> [6,] 4.446454 4.443953
#> [7,] 4.225760 4.070059
#> [8,] 4.955137 4.940265
#> [9,] 4.830680 4.879056
#> [10,] 4.074530 4.347345
#> [11,] 4.145441 4.245575
#> [12,] 4.252533 4.412242
#> [13,] 4.397974 4.650442
#> [14,] 5.007959 4.873156
#> [15,] 4.076700 4.307522
#> [16,] 4.402315 4.269174
#> CGTCTACTCCACGTTC-500.1.1 CGTGTAACATTGAGCT-500.1.1
#> [1,] 4.512136 4.442263
#> [2,] 4.174757 4.341801
#> [3,] 4.144013 4.314088
#> [4,] 4.118123 4.073903
#> [5,] 4.444984 4.844111
#> [6,] 4.272654 4.533487
#> [7,] 4.207929 4.464203
#> [8,] 4.779126 4.886836
#> [9,] 4.638350 4.784065
#> [10,] 4.341424 4.095843
#> [11,] 4.089806 4.351039
#> [12,] 4.445793 4.337182
#> [13,] 4.487864 4.780600
#> [14,] 4.115696 4.064665
#> [15,] 3.964401 4.032333
#> [16,] 4.331715 4.505774
#> CGTGTCTAGGCATGTG-500.1.1 CGTTAGAAGCTCAACT-500.1.1
#> [1,] 4.475515 4.405622
#> [2,] 4.225515 4.347390
#> [3,] 4.068299 4.408635
#> [4,] 4.145619 4.513052
#> [5,] 4.197165 4.287149
#> [6,] 4.503866 4.412651
#> [7,] 4.345361 4.222892
#> [8,] 4.731959 4.918675
#> [9,] 4.914948 4.457831
#> [10,] 4.081186 4.324297
#> [11,] 4.144330 4.421687
#> [12,] 4.559278 4.461847
#> [13,] 4.434278 4.475904
#> [14,] 4.344072 4.324297
#> [15,] 4.313144 4.126506
#> [16,] 4.895619 4.590361
#> CGTTAGAAGGCTACGA-500.1.1 CGTTAGACAACCGCCA-500.1.1
#> [1,] 4.608204 4.564063
#> [2,] 4.403112 4.113281
#> [3,] 3.891089 4.310938
#> [4,] 4.487977 4.167969
#> [5,] 4.504950 4.484375
#> [6,] 4.404526 4.175781
#> [7,] 4.267327 3.925781
#> [8,] 5.106082 4.965625
#> [9,] 4.479491 5.049219
#> [10,] 4.274399 4.628906
#> [11,] 4.145686 4.607813
#> [12,] 4.553041 4.572656
#> [13,] 4.704385 4.489844
#> [14,] 4.356436 4.689844
#> [15,] 4.131542 4.258594
#> [16,] 4.280057 4.563281
#> CGTTCTGAGAGCTTCT-500.1.1 CGTTCTGCAGGTTTCA-500.1.1
#> [1,] 4.555388 4.523256
#> [2,] 4.483798 4.613108
#> [3,] 4.297664 4.271670
#> [4,] 4.400904 4.309725
#> [5,] 4.303693 4.766385
#> [6,] 4.555388 4.457717
#> [7,] 4.370008 4.251586
#> [8,] 5.055765 4.909091
#> [9,] 4.388093 5.127907
#> [10,] 4.329314 4.232558
#> [11,] 4.433308 4.165962
#> [12,] 4.655614 4.664905
#> [13,] 4.505652 4.382664
#> [14,] 4.298417 4.242072
#> [15,] 4.158252 4.145877
#> [16,] 4.475509 4.779070
#> CTAACTTTCAGTGTTG-500.1.1 CTAAGACCAAGTTCTG-500.1.1
#> [1,] 4.392019 4.4560
#> [2,] 4.212676 4.2568
#> [3,] 4.243192 4.4136
#> [4,] 4.302347 4.3920
#> [5,] 4.879812 4.3744
#> [6,] 4.332864 4.6672
#> [7,] 3.871362 4.3712
#> [8,] 5.467606 4.5456
#> [9,] 5.061972 4.6624
#> [10,] 4.208920 4.5616
#> [11,] 4.253991 4.5304
#> [12,] 4.288732 4.6240
#> [13,] 4.820188 4.3208
#> [14,] 4.300939 4.0368
#> [15,] 4.141315 4.2624
#> [16,] 4.502817 4.1008
#> CTAATGGGTCGGCATC-500.1.1 CTACACCCATCGACGC-500.1.1
#> [1,] 4.692402 4.503889
#> [2,] 4.486520 4.141746
#> [3,] 4.105392 4.297321
#> [4,] 4.609069 4.271392
#> [5,] 4.476716 4.756266
#> [6,] 4.339461 4.380294
#> [7,] 3.830882 4.034572
#> [8,] 5.112745 4.886776
#> [9,] 4.808824 4.570441
#> [10,] 4.303922 4.452031
#> [11,] 4.208333 4.474503
#> [12,] 4.806373 4.329300
#> [13,] 4.781863 4.471046
#> [14,] 4.269608 4.630942
#> [15,] 4.004902 4.240277
#> [16,] 4.925245 4.400173
#> CTACATTTCGGCGCAT-500.1.1 CTACCCAGTGGTTTCA-500.1.1
#> [1,] 4.418338 4.185547
#> [2,] 4.259790 4.339193
#> [3,] 4.418338 4.415365
#> [4,] 3.988539 4.571615
#> [5,] 4.787011 4.351562
#> [6,] 3.939828 4.580078
#> [7,] 3.955110 4.384115
#> [8,] 4.903534 5.089193
#> [9,] 4.581662 4.729167
#> [10,] 4.332378 4.539714
#> [11,] 4.182426 4.666016
#> [12,] 4.620821 4.337891
#> [13,] 5.014327 4.517578
#> [14,] 4.215855 4.323568
#> [15,] 3.950334 4.384115
#> [16,] 4.573066 4.338542
#> CTACCCATCAATACCG-500.1.1 CTACGTCAGGTCATCT-500.1.1
#> [1,] 4.518544 4.355166
#> [2,] 3.868819 4.276708
#> [3,] 3.995879 3.847986
#> [4,] 4.067995 4.047986
#> [5,] 5.210852 4.677408
#> [6,] 4.149382 4.092119
#> [7,] 4.683723 4.016462
#> [8,] 4.695742 4.920140
#> [9,] 4.422390 4.919089
#> [10,] 3.810440 4.038529
#> [11,] 4.070398 4.290368
#> [12,] 4.074863 4.445884
#> [13,] 4.757898 4.811208
#> [14,] 4.418613 4.060595
#> [15,] 3.830357 3.899475
#> [16,] 4.142170 4.345359
#> CTACGTCCACAGACTT-500.1.1 CTACGTCCAGTAGAGC-500.1.1
#> [1,] 4.411928 4.368567
#> [2,] 4.286408 4.236439
#> [3,] 4.516644 4.608484
#> [4,] 4.712205 4.385953
#> [5,] 4.696255 4.431154
#> [6,] 4.426491 4.418637
#> [7,] 4.223994 3.988178
#> [8,] 4.929958 4.880389
#> [9,] 4.789182 5.023644
#> [10,] 4.590153 4.528512
#> [11,] 4.513176 4.205146
#> [12,] 4.404300 4.387344
#> [13,] 4.456311 4.499305
#> [14,] 4.210818 4.171071
#> [15,] 4.131761 4.194019
#> [16,] 4.381415 4.781641
#> CTACGTCGTATTAGCC-500.1.1 CTAGAGTAGACAGACC-500.1.1
#> [1,] 4.405091 4.606965
#> [2,] 4.192515 4.325373
#> [3,] 4.355024 4.359204
#> [4,] 4.277647 4.325373
#> [5,] 4.584289 4.734328
#> [6,] 4.690492 4.235821
#> [7,] 4.116318 4.036816
#> [8,] 4.889076 4.880597
#> [9,] 4.952630 4.930348
#> [10,] 4.268712 4.135323
#> [11,] 4.454316 4.223881
#> [12,] 4.483311 4.657711
#> [13,] 4.441167 4.909453
#> [14,] 4.638065 4.352239
#> [15,] 4.248820 4.134328
#> [16,] 4.695887 4.756219
#> CTAGAGTTCCGAGCCA-500.1.1 CTAGAGTTCCGTAGGC-500.1.1
#> [1,] 4.182577 4.396335
#> [2,] 4.290558 4.552641
#> [3,] 4.525300 4.275961
#> [4,] 4.182577 4.350341
#> [5,] 4.661450 4.613367
#> [6,] 4.456964 4.286382
#> [7,] 4.098592 4.146604
#> [8,] 5.140845 4.875314
#> [9,] 5.081377 4.715056
#> [10,] 4.083985 4.329141
#> [11,] 4.322379 4.249731
#> [12,] 4.471570 4.473230
#> [13,] 4.456964 4.534675
#> [14,] 4.255086 4.232124
#> [15,] 4.076682 4.180381
#> [16,] 4.484611 4.674811
#> CTAGTGAAGATAGCAT-500.1.1 CTAGTGAAGTAACCCT-500.1.1
#> [1,] 4.427111 4.703550
#> [2,] 3.994621 3.874136
#> [3,] 4.459387 4.034578
#> [4,] 4.369016 4.481789
#> [5,] 4.587413 4.510834
#> [6,] 4.609467 4.100507
#> [7,] 4.291555 4.123098
#> [8,] 4.901560 4.498847
#> [9,] 4.775148 4.531120
#> [10,] 4.392684 4.236515
#> [11,] 4.552448 4.079760
#> [12,] 4.401829 4.262794
#> [13,] 4.117805 4.326879
#> [14,] 4.506724 4.408022
#> [15,] 4.167832 3.954818
#> [16,] 4.562668 3.996773
#> CTAGTGACAAGTCTAC-500.1.1 CTAGTGAGTAAAGGAG-500.1.1
#> [1,] 4.243463 4.470101
#> [2,] 3.893598 4.064914
#> [3,] 3.900812 4.104251
#> [4,] 4.128945 4.139354
#> [5,] 4.272317 4.736814
#> [6,] 5.095582 3.976363
#> [7,] 4.027051 4.530252
#> [8,] 4.671776 4.509614
#> [9,] 4.463481 4.336567
#> [10,] 4.107304 3.932263
#> [11,] 4.198377 4.024872
#> [12,] 4.304779 4.312048
#> [13,] 4.095582 4.554948
#> [14,] 5.083859 4.155936
#> [15,] 4.057710 4.315929
#> [16,] 4.972949 4.289469
#> CTAGTGAGTAGGCATG-500.1.1 CTCACACAGCCGTCGT-500.1.1
#> [1,] 4.490683 4.115889
#> [2,] 4.427191 4.295918
#> [3,] 4.353347 4.594752
#> [4,] 4.463078 4.064140
#> [5,] 4.528640 4.419096
#> [6,] 4.398896 4.486880
#> [7,] 4.277433 4.284257
#> [8,] 4.871636 4.897959
#> [9,] 4.891649 4.752187
#> [10,] 4.295376 4.153790
#> [11,] 4.220152 4.349854
#> [12,] 4.466529 4.390671
#> [13,] 4.547274 4.542274
#> [14,] 4.532781 4.199708
#> [15,] 4.135266 4.314140
#> [16,] 4.458247 4.424927
#> CTCAGAAAGACGACGT-500.1.1 CTCAGAAAGTACTTGC-500.1.1
#> [1,] 4.352326 4.310524
#> [2,] 4.126163 4.231726
#> [3,] 4.450581 4.648004
#> [4,] 4.219186 4.172110
#> [5,] 4.523837 4.557284
#> [6,] 4.368023 4.584241
#> [7,] 4.201744 4.391913
#> [8,] 4.936047 4.801452
#> [9,] 5.018605 4.656817
#> [10,] 4.260465 4.573354
#> [11,] 4.527326 4.656817
#> [12,] 4.197674 4.424054
#> [13,] 4.386628 4.237429
#> [14,] 4.315116 4.466563
#> [15,] 4.157558 4.187144
#> [16,] 4.798837 4.362364
#> CTCATTAGTACCTACA-500.1.1 CTCGAAAGTAAGGGCT-500.1.1
#> [1,] 4.401906 4.286830
#> [2,] 4.366958 4.139509
#> [3,] 4.391581 4.271205
#> [4,] 4.433678 3.963170
#> [5,] 4.177919 4.264509
#> [6,] 4.055600 4.476563
#> [7,] 4.148531 4.399554
#> [8,] 4.899126 4.650670
#> [9,] 4.977760 4.393973
#> [10,] 4.179508 4.159598
#> [11,] 4.281176 4.370536
#> [12,] 4.442415 4.545759
#> [13,] 4.409849 4.629464
#> [14,] 4.457506 4.339286
#> [15,] 4.127879 4.118304
#> [16,] 4.285147 5.008929
#> CTCGAGGTCTGCAAGT-500.1.1 CTCGGAGAGCACCGCT-500.1.1
#> [1,] 4.754845 4.457808
#> [2,] 4.022001 4.471387
#> [3,] 4.191723 4.202716
#> [4,] 4.111577 4.300679
#> [5,] 4.509167 4.721629
#> [6,] 4.448402 4.343356
#> [7,] 4.135673 4.237633
#> [8,] 4.882661 4.839961
#> [9,] 4.939759 4.962173
#> [10,] 4.188580 4.102813
#> [11,] 4.103719 4.231814
#> [12,] 4.498167 4.458778
#> [13,] 4.871137 4.766246
#> [14,] 4.142483 4.209505
#> [15,] 4.236249 4.287100
#> [16,] 4.599267 4.618817
#> CTCGGAGGTGAGTGAC-500.1.1 CTCGGGACATGCAATC-500.1.1
#> [1,] 4.194573 4.434097
#> [2,] 4.874917 4.635387
#> [3,] 4.277300 4.568052
#> [4,] 4.487756 4.362464
#> [5,] 4.100596 4.227794
#> [6,] 4.246195 4.224928
#> [7,] 4.061549 4.026504
#> [8,] 4.731966 4.968481
#> [9,] 4.985440 5.516476
#> [10,] 4.881535 4.291547
#> [11,] 4.217737 3.984957
#> [12,] 4.256784 4.381089
#> [13,] 4.420913 4.613897
#> [14,] 4.414957 4.469914
#> [15,] 4.872270 4.123926
#> [16,] 4.230973 4.082378
#> CTCGGGAGTCTTGATG-500.1.1 CTCGTACAGTGGTAGC-500.1.1
#> [1,] 4.102313 4.398677
#> [2,] 4.318851 4.315964
#> [3,] 4.747722 4.493797
#> [4,] 4.196917 4.648470
#> [5,] 4.300631 4.244003
#> [6,] 4.135950 4.473945
#> [7,] 4.071479 4.104218
#> [8,] 4.846531 4.927213
#> [9,] 5.151367 4.579818
#> [10,] 4.217239 4.361456
#> [11,] 4.334268 3.944582
#> [12,] 4.429573 4.641026
#> [13,] 4.419061 4.500414
#> [14,] 4.654520 4.835401
#> [15,] 3.936230 4.420182
#> [16,] 4.540294 4.389578
#> CTCGTACGTAGAAAGG-500.1.1 CTCGTCACATGTTCCC-500.1.1
#> [1,] 4.292851 4.299859
#> [2,] 4.392765 4.277228
#> [3,] 4.590870 4.063178
#> [4,] 4.210164 3.975483
#> [5,] 4.281654 4.495521
#> [6,] 4.661499 3.981612
#> [7,] 4.132644 3.771334
#> [8,] 4.933678 4.913248
#> [9,] 4.931955 4.859500
#> [10,] 4.635659 3.771806
#> [11,] 4.434970 4.227723
#> [12,] 4.446167 4.547383
#> [13,] 4.543497 4.947195
#> [14,] 4.242033 4.184347
#> [15,] 4.031869 3.831683
#> [16,] 4.478898 4.443187
#> CTCTAATAGACTAAGT-500.1.1 CTCTAATCACTTAAGC-500.1.1
#> [1,] 4.409475 4.636863
#> [2,] 4.311337 4.603137
#> [3,] 4.157360 4.014118
#> [4,] 4.338409 4.225882
#> [5,] 4.652284 4.347451
#> [6,] 4.366328 4.340392
#> [7,] 4.232657 4.263529
#> [8,] 4.847716 4.915294
#> [9,] 4.769036 4.147451
#> [10,] 4.115905 5.064314
#> [11,] 4.133672 4.660392
#> [12,] 4.588832 4.484706
#> [13,] 4.400169 4.510588
#> [14,] 3.988156 4.272157
#> [15,] 4.100677 3.825098
#> [16,] 4.794416 4.305098
#> CTCTACGAGAGAACAG-500.1.1 CTCTACGCACCTCGGA-500.1.1
#> [1,] 4.539276 4.091662
#> [2,] 4.485437 4.595506
#> [3,] 4.240953 4.364873
#> [4,] 4.218005 4.313424
#> [5,] 4.517211 4.424601
#> [6,] 4.230362 4.162034
#> [7,] 4.383054 4.408634
#> [8,] 5.029126 4.856889
#> [9,] 4.506620 4.751626
#> [10,] 4.283319 4.424009
#> [11,] 4.075905 4.690124
#> [12,] 4.535746 4.754583
#> [13,] 4.655781 4.634536
#> [14,] 4.470432 4.261384
#> [15,] 4.283319 4.450621
#> [16,] 4.567520 4.599054
#> CTCTGGTAGGGAACGG-500.1.1 CTCTGGTAGTGTACGG-500.1.1
#> [1,] 4.264286 4.438202
#> [2,] 4.289286 3.982210
#> [3,] 4.345833 4.368914
#> [4,] 4.426190 4.125468
#> [5,] 4.632143 4.814607
#> [6,] 4.397619 4.672285
#> [7,] 3.901190 4.273408
#> [8,] 4.993452 4.346442
#> [9,] 4.976786 4.446629
#> [10,] 4.093452 4.375468
#> [11,] 4.332738 4.602060
#> [12,] 4.533333 4.426966
#> [13,] 4.539881 4.000000
#> [14,] 4.342857 4.481273
#> [15,] 4.301786 4.413858
#> [16,] 4.728571 4.634831
#> CTCTGGTTCCCTAATT-500.1.1 CTCTGGTTCTGGTTCC-500.1.1
#> [1,] 4.286200 4.879630
#> [2,] 4.475867 4.240741
#> [3,] 4.199184 4.415509
#> [4,] 4.458192 4.388889
#> [5,] 4.671652 4.917824
#> [6,] 4.513256 4.030093
#> [7,] 4.184228 3.869213
#> [8,] 5.196465 4.990741
#> [9,] 4.430320 5.061343
#> [10,] 4.365738 4.239583
#> [11,] 4.802855 4.387731
#> [12,] 4.493542 4.668981
#> [13,] 4.639021 4.626157
#> [14,] 4.535010 4.305556
#> [15,] 4.460231 3.930556
#> [16,] 4.372536 4.471065
#> CTGAAACAGTTCGCGC-500.1.1 CTGAAACCAAACCCAT-500.1.1
#> [1,] 4.323977 4.483949
#> [2,] 4.373099 4.304173
#> [3,] 4.625731 3.946228
#> [4,] 4.666667 4.262440
#> [5,] 4.189474 4.554575
#> [6,] 4.338596 4.741573
#> [7,] 4.450877 4.257624
#> [8,] 4.725731 5.190209
#> [9,] 4.453801 4.644462
#> [10,] 4.728070 4.200642
#> [11,] 4.560234 4.245586
#> [12,] 4.551462 4.581862
#> [13,] 4.460819 4.807384
#> [14,] 4.351462 4.132424
#> [15,] 4.198830 4.207865
#> [16,] 4.309942 4.415730
#> CTGAAACTCACTTATC-500.1.1 CTGAAGTCACGGTGTC-500.1.1
#> [1,] 4.730388 4.319223
#> [2,] 4.453562 4.289382
#> [3,] 4.443643 4.213046
#> [4,] 4.517583 4.625260
#> [5,] 4.385032 4.558640
#> [6,] 4.855726 4.749480
#> [7,] 4.114518 4.237335
#> [8,] 5.049594 4.993754
#> [9,] 4.724977 5.001388
#> [10,] 4.307484 4.892436
#> [11,] 4.241659 4.605135
#> [12,] 4.429216 4.360167
#> [13,] 4.202885 4.394865
#> [14,] 4.646528 4.759889
#> [15,] 4.032462 4.229702
#> [16,] 4.477006 4.302568
#> CTGAAGTGTAAGGGCT-500.1.1 CTGAAGTGTCTCACCT-500.1.1
#> [1,] 4.301693 4.548291
#> [2,] 4.559855 4.424963
#> [3,] 4.327086 4.124071
#> [4,] 4.594317 4.305349
#> [5,] 4.189843 4.536404
#> [6,] 4.418380 4.387073
#> [7,] 4.747279 4.476969
#> [8,] 4.770859 4.987370
#> [9,] 4.697703 4.719911
#> [10,] 4.509069 4.399703
#> [11,] 4.342805 4.252600
#> [12,] 4.687424 4.566122
#> [13,] 4.470375 4.636701
#> [14,] 4.278718 4.181278
#> [15,] 4.401451 4.305349
#> [16,] 4.570133 4.775632
#> CTGAAGTGTTAAAGTG-500.1.1 CTGATAGCAAGTTGTC-500.1.1
#> [1,] 4.437941 4.312110
#> [2,] 4.465187 4.353308
#> [3,] 4.004036 4.527466
#> [4,] 4.154390 4.189139
#> [5,] 4.491423 4.361423
#> [6,] 4.479314 4.433833
#> [7,] 4.591322 4.444444
#> [8,] 4.836529 4.914482
#> [9,] 4.709384 4.672285
#> [10,] 4.250252 4.418851
#> [11,] 4.187689 4.734082
#> [12,] 4.498486 4.667291
#> [13,] 4.244198 4.145443
#> [14,] 4.285570 4.204120
#> [15,] 4.236125 4.273408
#> [16,] 4.628658 4.380150
#> CTGATCCAGTACTTGC-500.1.1 CTGATCCTCTTGCCGT-500.1.1
#> [1,] 4.729801 4.523996
#> [2,] 4.747020 4.351616
#> [3,] 4.079470 4.278159
#> [4,] 4.247682 4.283056
#> [5,] 4.262252 4.646425
#> [6,] 4.378808 4.152791
#> [7,] 4.413245 4.421156
#> [8,] 4.894040 4.714006
#> [9,] 4.762914 4.521058
#> [10,] 4.411921 4.348678
#> [11,] 3.993377 3.969638
#> [12,] 4.238411 4.340842
#> [13,] 4.572185 4.404505
#> [14,] 4.398675 4.374143
#> [15,] 4.274172 4.320274
#> [16,] 4.464901 4.820764
#> CTGCGGACAGGCTCAC-500.1.1 CTGCGGACAGTAACGG-500.1.1
#> [1,] 4.451012 4.646070
#> [2,] 4.141700 4.060881
#> [3,] 4.191093 4.303498
#> [4,] 4.446964 4.318946
#> [5,] 4.243725 4.723308
#> [6,] 4.140891 4.971377
#> [7,] 4.369231 4.231713
#> [8,] 4.607287 4.887778
#> [9,] 4.715789 4.659700
#> [10,] 4.444534 4.368469
#> [11,] 4.248583 4.672876
#> [12,] 4.642915 4.358473
#> [13,] 4.674494 4.338028
#> [14,] 4.017814 4.709677
#> [15,] 4.078543 4.454339
#> [16,] 4.827530 4.315311
#> CTGGTCTAGCTTTGGT-500.1.1 CTGTGCTCATACTACG-500.1.1
#> [1,] 4.283951 4.234043
#> [2,] 4.353909 3.890957
#> [3,] 4.163237 4.183511
#> [4,] 4.378601 4.086879
#> [5,] 4.541838 4.593085
#> [6,] 4.227709 4.687057
#> [7,] 4.412894 3.954787
#> [8,] 4.739369 4.835993
#> [9,] 4.565158 4.543440
#> [10,] 4.164609 4.347518
#> [11,] 4.203018 4.270390
#> [12,] 4.802469 4.216312
#> [13,] 4.920439 4.537234
#> [14,] 4.330590 4.777482
#> [15,] 3.862826 4.054078
#> [16,] 4.264746 4.867908
#> CTGTGCTTCGGTGTCG-500.1.1 CTTAACTCAGATCCAT-500.1.1
#> [1,] 4.828066 4.375156
#> [2,] 4.471555 4.409488
#> [3,] 4.275601 4.309613
#> [4,] 4.537295 4.406991
#> [5,] 4.575221 4.440699
#> [6,] 4.322377 4.616729
#> [7,] 4.112516 4.370162
#> [8,] 4.946903 4.965044
#> [9,] 4.897598 5.012484
#> [10,] 4.103666 4.703496
#> [11,] 4.399494 4.352684
#> [12,] 4.503161 4.345818
#> [13,] 4.806574 4.382647
#> [14,] 4.403287 4.395755
#> [15,] 4.079646 4.537453
#> [16,] 4.096081 4.263421
#> CTTACCGGTCCGTTAA-500.1.1 CTTAGGAGTCGCATCG-500.1.1
#> [1,] 4.526957 4.328571
#> [2,] 4.142609 4.527381
#> [3,] 4.386087 4.340476
#> [4,] 4.247536 4.358929
#> [5,] 4.514203 4.549405
#> [6,] 4.463768 4.269048
#> [7,] 4.250435 4.538095
#> [8,] 4.906667 4.894643
#> [9,] 4.822609 4.660714
#> [10,] 4.424928 4.571429
#> [11,] 4.526377 4.428571
#> [12,] 4.472464 4.873810
#> [13,] 4.117101 4.688690
#> [14,] 4.506667 4.333333
#> [15,] 4.107246 4.608929
#> [16,] 4.309565 4.563095
#> CTTAGGAGTGTGGCTC-500.1.1 CTTCTCTAGTTAAGTG-500.1.1
#> [1,] 4.721866 4.495700
#> [2,] 4.366880 4.215602
#> [3,] 4.578225 4.372850
#> [4,] 4.411711 4.377150
#> [5,] 4.225069 4.412162
#> [6,] 4.266240 4.466216
#> [7,] 4.387008 4.138206
#> [8,] 4.854529 4.782555
#> [9,] 4.718207 4.761671
#> [10,] 4.225984 4.381450
#> [11,] 4.266240 4.351351
#> [12,] 4.755718 4.385749
#> [13,] 4.503202 4.547297
#> [14,] 4.225984 4.537469
#> [15,] 4.279048 4.116708
#> [16,] 4.318390 4.357494
#> CTTGGCTGTGTCGCTG-500.1.1 CTTTGCGGTTACGGAG-500.1.1
#> [1,] 4.745774 4.261884
#> [2,] 3.495605 4.419188
#> [3,] 3.627451 4.581677
#> [4,] 4.066261 4.278306
#> [5,] 5.312373 4.448574
#> [6,] 3.972279 4.223855
#> [7,] 4.897904 4.026793
#> [8,] 4.225152 4.610199
#> [9,] 4.330629 4.514261
#> [10,] 3.845842 4.121867
#> [11,] 3.868154 4.352636
#> [12,] 4.236646 4.278306
#> [13,] 4.340771 4.343993
#> [14,] 4.311697 4.306828
#> [15,] 3.926978 4.238548
#> [16,] 3.939148 4.509939
#> GAAACTCAGATCCCGC-500.1.1 GAAACTCGTTAAGATG-500.1.1
#> [1,] 4.342898 4.399237
#> [2,] 4.034433 4.156389
#> [3,] 4.490674 4.344565
#> [4,] 4.319943 4.450731
#> [5,] 4.994261 4.356008
#> [6,] 4.061693 4.359822
#> [7,] 4.370158 4.416402
#> [8,] 5.025825 4.847425
#> [9,] 4.318508 4.553083
#> [10,] 4.317073 4.596313
#> [11,] 4.519369 4.164018
#> [12,] 4.558106 4.481882
#> [13,] 4.053085 4.390337
#> [14,] 4.418938 4.263191
#> [15,] 4.340029 4.361729
#> [16,] 4.189383 4.198347
#> GAAATGACACCTCGTT-500.1.1 GAAATGAGTCTCTTTA-500.1.1
#> [1,] 4.627219 4.551285
#> [2,] 4.523077 3.822810
#> [3,] 4.355030 4.204642
#> [4,] 4.142012 4.196905
#> [5,] 4.687574 4.701772
#> [6,] 4.242604 4.317444
#> [7,] 4.292308 4.428251
#> [8,] 4.904142 4.589718
#> [9,] 4.843787 4.520339
#> [10,] 4.284024 4.116546
#> [11,] 4.292308 4.347392
#> [12,] 4.378698 4.338907
#> [13,] 4.435503 4.175942
#> [14,] 4.326627 4.258797
#> [15,] 4.046154 4.146494
#> [16,] 4.575148 4.213876
#> GAACATCCATATGGTC-500.1.1 GAACATCGTTACGTCA-500.1.1
#> [1,] 4.271670 3.985809
#> [2,] 4.509514 4.036897
#> [3,] 4.137421 4.197729
#> [4,] 4.335095 4.104068
#> [5,] 4.472516 4.137181
#> [6,] 4.144820 4.909177
#> [7,] 4.271670 4.008515
#> [8,] 4.991543 4.864711
#> [9,] 5.100423 4.520341
#> [10,] 4.459831 3.910123
#> [11,] 4.257928 4.296121
#> [12,] 4.492600 4.484390
#> [13,] 4.436575 4.166509
#> [14,] 4.423890 4.873226
#> [15,] 4.381607 4.123936
#> [16,] 4.568710 4.716178
#> GAACCTAAGGATGCGT-500.1.1 GAACCTAGTCCAAGTT-500.1.1
#> [1,] 4.745937 3.860870
#> [2,] 4.281437 3.987578
#> [3,] 4.017109 3.865839
#> [4,] 4.236099 4.159006
#> [5,] 4.419162 4.280745
#> [6,] 4.436270 5.434783
#> [7,] 3.869119 4.104348
#> [8,] 4.919589 4.709317
#> [9,] 4.592814 4.450932
#> [10,] 4.279726 3.946584
#> [11,] 4.023097 3.997516
#> [12,] 4.493584 4.636025
#> [13,] 4.706587 3.995031
#> [14,] 4.352438 5.146584
#> [15,] 4.086399 4.211180
#> [16,] 4.385800 4.777640
#> GAACGGAAGGAGCGAG-500.1.1 GAACGGACAGTAGAGC-500.1.1
#> [1,] 4.318830 4.595726
#> [2,] 3.834209 4.406055
#> [3,] 4.108027 4.097061
#> [4,] 4.152288 4.153161
#> [5,] 4.720930 4.477293
#> [6,] 4.003001 4.634016
#> [7,] 4.904726 4.219056
#> [8,] 4.702176 4.864648
#> [9,] 4.157539 4.586821
#> [10,] 3.948987 4.788958
#> [11,] 3.871718 4.333927
#> [12,] 4.327082 4.430988
#> [13,] 4.321080 4.587711
#> [14,] 4.050263 4.702582
#> [15,] 4.093023 4.214604
#> [16,] 4.091523 4.426536
#> GAACGGACAGTGACAG-500.1.1 GAACGGATCAACACAC-500.1.1
#> [1,] 4.420348 4.421491
#> [2,] 4.218652 4.407596
#> [3,] 4.408300 4.263085
#> [4,] 4.318608 4.431218
#> [5,] 4.680054 4.548402
#> [6,] 4.357430 4.283928
#> [7,] 3.896475 4.052339
#> [8,] 5.215975 4.656786
#> [9,] 5.116912 4.396017
#> [10,] 4.323963 4.113942
#> [11,] 4.423472 4.189440
#> [12,] 4.446229 4.584993
#> [13,] 4.664882 4.654006
#> [14,] 4.693440 4.196387
#> [15,] 4.045962 4.232978
#> [16,] 4.423918 4.608152
#> GAAGCAGCAATGGTCT-500.1.1 GAATGAAAGAGCTATA-500.1.1
#> [1,] 4.334946 4.368655
#> [2,] 4.729141 4.075690
#> [3,] 4.253325 4.523598
#> [4,] 4.231560 4.181656
#> [5,] 4.356711 4.662511
#> [6,] 4.446796 4.199466
#> [7,] 4.323458 4.161175
#> [8,] 4.818017 4.824577
#> [9,] 4.252116 4.379341
#> [10,] 4.590689 4.288513
#> [11,] 4.336155 4.340160
#> [12,] 4.286578 4.516474
#> [13,] 4.688634 4.181656
#> [14,] 4.233978 4.138914
#> [15,] 4.030230 4.223508
#> [16,] 4.428658 4.690116
#> GAATGAAAGTGCGATG-500.1.1 GACAGAGAGGGTGTGT-500.1.1
#> [1,] 4.407169 4.534331
#> [2,] 4.017463 4.223592
#> [3,] 4.132353 4.149648
#> [4,] 4.368566 4.475352
#> [5,] 4.699449 4.315141
#> [6,] 4.809743 3.978873
#> [7,] 4.212316 4.345070
#> [8,] 4.877757 4.785211
#> [9,] 4.632353 4.561620
#> [10,] 4.558824 4.213908
#> [11,] 4.410846 4.033451
#> [12,] 4.545037 4.313380
#> [13,] 4.372243 4.591549
#> [14,] 4.265625 3.989437
#> [15,] 4.125919 3.951585
#> [16,] 4.329044 4.749120
#> GACAGAGCATGCAATC-500.1.1 GACAGAGGTCCAACTA-500.1.1
#> [1,] 3.995466 4.471922
#> [2,] 4.834845 3.944924
#> [3,] 4.031088 4.327214
#> [4,] 3.852332 4.315335
#> [5,] 4.551490 4.413607
#> [6,] 4.183938 4.201944
#> [7,] 3.874676 4.188985
#> [8,] 5.259067 5.033477
#> [9,] 4.358808 5.092873
#> [10,] 4.045013 4.200864
#> [11,] 4.544689 4.367171
#> [12,] 4.030440 4.487041
#> [13,] 4.487370 4.506479
#> [14,] 4.988990 4.639309
#> [15,] 3.785298 4.455724
#> [16,] 4.547280 4.177106
#> GACCAATGTTTGCATG-500.1.1 GACCTGGAGGTGCTTT-500.1.1
#> [1,] 4.580675 4.167292
#> [2,] 4.454877 4.167292
#> [3,] 4.309936 4.560390
#> [4,] 4.329079 4.505626
#> [5,] 4.693710 4.446362
#> [6,] 4.234275 4.474119
#> [7,] 4.241568 4.228807
#> [8,] 4.915223 5.107277
#> [9,] 4.298997 4.855964
#> [10,] 4.567001 4.254314
#> [11,] 4.262534 4.518380
#> [12,] 4.648131 4.312828
#> [13,] 4.317229 4.484621
#> [14,] 4.226983 4.318080
#> [15,] 4.391978 4.002251
#> [16,] 4.466727 4.564891
#> GACCTGGCACAAGCCC-500.1.1 GACGCGTGTTGCCTCT-500.1.1
#> [1,] 4.196262 4.979090
#> [2,] 4.209613 4.393604
#> [3,] 4.579439 3.997540
#> [4,] 4.373832 4.274293
#> [5,] 4.719626 4.804428
#> [6,] 4.356475 4.485855
#> [7,] 4.339119 4.087331
#> [8,] 5.101469 4.849938
#> [9,] 4.727637 4.774908
#> [10,] 4.268358 4.289053
#> [11,] 4.588785 3.985240
#> [12,] 4.345794 4.527675
#> [13,] 4.520694 4.963100
#> [14,] 4.444593 4.146371
#> [15,] 4.121495 4.084871
#> [16,] 4.405874 4.653137
#> GACGTGCAGTCGTACT-500.1.1 GACGTGCCAACACCTA-500.1.1
#> [1,] 4.427390 4.543331
#> [2,] 4.390625 4.259231
#> [3,] 4.159007 4.676714
#> [4,] 4.088235 4.497362
#> [5,] 4.477941 4.519216
#> [6,] 4.347426 4.735494
#> [7,] 4.556066 4.347400
#> [8,] 4.727022 4.993971
#> [9,] 4.840074 4.746044
#> [10,] 4.199449 4.400151
#> [11,] 4.002757 4.326300
#> [12,] 4.351103 4.679729
#> [13,] 4.371324 4.274303
#> [14,] 4.063419 4.386586
#> [15,] 4.075368 4.163527
#> [16,] 4.896140 4.235870
#> GACGTGCCAGATTGCT-500.1.1 GACGTGCTCCCACTTG-500.1.1
#> [1,] 4.387962 4.344495
#> [2,] 4.250379 4.226658
#> [3,] 4.449671 4.141661
#> [4,] 4.368235 4.813265
#> [5,] 4.529084 4.341919
#> [6,] 4.341932 4.497746
#> [7,] 4.106727 4.345782
#> [8,] 5.001012 4.889247
#> [9,] 4.846232 4.811977
#> [10,] 4.274659 4.500966
#> [11,] 4.480526 4.316162
#> [12,] 4.164390 4.412750
#> [13,] 4.389479 4.363812
#> [14,] 4.555387 4.639408
#> [15,] 4.334345 4.318094
#> [16,] 4.685888 4.162910
#> GACGTGCTCGCTAGCG-500.1.1 GACGTTAAGCAGCGTA-500.1.1
#> [1,] 4.263753 4.260170
#> [2,] 4.304370 4.115421
#> [3,] 4.518766 4.006623
#> [4,] 4.351671 4.325449
#> [5,] 4.438046 4.852412
#> [6,] 4.391774 4.340587
#> [7,] 3.966067 4.346263
#> [8,] 5.013368 5.096500
#> [9,] 4.904370 5.168401
#> [10,] 4.422108 4.413434
#> [11,] 4.372751 4.272469
#> [12,] 4.366067 4.241249
#> [13,] 4.572751 4.623463
#> [14,] 4.183033 3.819300
#> [15,] 4.111054 3.931883
#> [16,] 4.650386 4.670766
#> GACTAACAGGACAGAA-500.1.1 GACTACACAGACAAAT-500.1.1
#> [1,] 4.436865 4.444992
#> [2,] 4.307329 4.232348
#> [3,] 4.356676 4.139573
#> [4,] 4.327649 4.272578
#> [5,] 4.676343 4.715928
#> [6,] 4.322932 4.224138
#> [7,] 4.232946 4.167488
#> [8,] 4.924528 5.087028
#> [9,] 4.864659 4.888342
#> [10,] 4.380987 4.290640
#> [11,] 4.355951 4.265189
#> [12,] 4.516691 4.380952
#> [13,] 4.659289 4.414614
#> [14,] 4.531567 4.613300
#> [15,] 4.021771 4.596059
#> [16,] 4.332003 4.573892
#> GACTGCGTCAATCACG-500.1.1 GAGCAGAGTGATGTCT-500.1.1
#> [1,] 4.384135 4.477419
#> [2,] 4.045455 4.203687
#> [3,] 4.390374 4.254378
#> [4,] 4.193405 4.906912
#> [5,] 4.670232 4.360369
#> [6,] 3.905526 4.233180
#> [7,] 4.273619 4.388940
#> [8,] 4.768271 4.749309
#> [9,] 4.393048 4.504147
#> [10,] 4.229055 4.247926
#> [11,] 4.251337 4.522581
#> [12,] 4.623886 4.537327
#> [13,] 4.374332 4.396313
#> [14,] 4.038324 4.354839
#> [15,] 4.154189 4.267281
#> [16,] 4.327986 4.255300
#> GAGCAGATCCGTAGGC-500.1.1 GAGGTGACACGTTGGC-500.1.1
#> [1,] 4.303348 4.318212
#> [2,] 4.167003 4.387245
#> [3,] 4.266236 4.698882
#> [4,] 4.265833 4.358974
#> [5,] 4.595805 4.367521
#> [6,] 4.652279 4.099277
#> [7,] 4.127874 4.113083
#> [8,] 5.021380 4.678501
#> [9,] 4.871319 4.800131
#> [10,] 4.494958 4.431295
#> [11,] 4.544574 4.422091
#> [12,] 4.365067 4.330703
#> [13,] 4.399355 4.421433
#> [14,] 4.678499 4.345168
#> [15,] 4.274304 4.310322
#> [16,] 4.675676 4.602893
#> GAGTCCGAGCACCGTC-500.1.1 GAGTCCGGTGTCTGAT-500.1.1
#> [1,] 4.439162 4.237440
#> [2,] 4.113618 4.494019
#> [3,] 4.269138 4.486842
#> [4,] 4.188558 4.311005
#> [5,] 4.326350 4.652512
#> [6,] 4.479452 4.400718
#> [7,] 4.125705 3.954545
#> [8,] 4.921031 5.038876
#> [9,] 4.655923 5.049043
#> [10,] 4.456084 4.180622
#> [11,] 4.291700 4.324163
#> [12,] 4.682514 4.297249
#> [13,] 4.787268 4.444378
#> [14,] 4.187752 4.267943
#> [15,] 4.039484 4.080742
#> [16,] 4.427075 4.790072
#> GATCGATAGAGGTTGC-500.1.1 GATCGATCACAGACAG-500.1.1
#> [1,] 4.380491 4.225904
#> [2,] 4.318690 4.388554
#> [3,] 4.306776 4.641566
#> [4,] 4.262100 4.390813
#> [5,] 4.588235 4.654367
#> [6,] 4.532390 4.331325
#> [7,] 4.357409 4.323042
#> [8,] 4.434103 4.899096
#> [9,] 4.557707 4.892319
#> [10,] 4.329859 4.305723
#> [11,] 4.445272 4.652108
#> [12,] 4.570365 4.284639
#> [13,] 4.276992 4.679970
#> [14,] 4.148176 4.405120
#> [15,] 4.244974 3.879518
#> [16,] 4.483991 4.570030
#> GATCGATCACTTCTGC-500.1.1 GATCGATGTCGCATAT-500.1.1
#> [1,] 4.401524 4.502392
#> [2,] 4.499281 3.735646
#> [3,] 4.201553 4.043062
#> [4,] 4.478148 3.846890
#> [5,] 4.319436 4.921053
#> [6,] 4.302329 4.119617
#> [7,] 4.108539 3.848086
#> [8,] 4.803191 5.132775
#> [9,] 4.848476 4.528708
#> [10,] 4.290253 4.452153
#> [11,] 4.207734 4.205742
#> [12,] 4.420357 4.448565
#> [13,] 4.400230 5.227273
#> [14,] 4.587550 4.183014
#> [15,] 4.392467 4.029904
#> [16,] 4.465066 4.537081
#> GATCGCGTCTCTAGGA-500.1.1 GATCGTAAGCTAACTC-500.1.1
#> [1,] 4.264317 4.406871
#> [2,] 4.477974 3.971440
#> [3,] 4.653084 4.378725
#> [4,] 4.392070 4.275248
#> [5,] 4.651982 4.631209
#> [6,] 4.342511 4.859685
#> [7,] 4.024229 4.090232
#> [8,] 5.167401 4.732202
#> [9,] 4.959251 4.766970
#> [10,] 4.313877 4.512831
#> [11,] 4.405286 4.712748
#> [12,] 4.368943 4.462748
#> [13,] 4.561674 4.099752
#> [14,] 4.496696 4.903974
#> [15,] 4.270925 4.342715
#> [16,] 4.539648 4.677566
#> GATGAAAAGTCAAGGC-500.1.1 GATGAAACAAAGCAAT-500.1.1
#> [1,] 4.388073 4.397333
#> [2,] 4.188418 4.057333
#> [3,] 3.955920 4.725333
#> [4,] 4.343993 4.382667
#> [5,] 4.745030 4.840667
#> [6,] 4.831461 4.232000
#> [7,] 4.050130 4.096000
#> [8,] 5.040622 5.342667
#> [9,] 4.724287 4.818667
#> [10,] 4.221262 4.346000
#> [11,] 4.097666 4.633333
#> [12,] 4.526361 4.177333
#> [13,] 4.344857 4.491333
#> [14,] 4.792567 4.113333
#> [15,] 4.197926 4.179333
#> [16,] 4.705272 4.166667
#> GATGAAACACAAGTAA-500.1.1 GATGAGGAGGATGTAT-500.1.1
#> [1,] 4.645833 4.331984
#> [2,] 4.282407 4.457490
#> [3,] 4.352623 4.655061
#> [4,] 4.114969 4.428340
#> [5,] 4.435185 4.276923
#> [6,] 4.503086 4.041296
#> [7,] 4.186728 4.199190
#> [8,] 5.086420 4.917409
#> [9,] 4.647377 4.923077
#> [10,] 4.330247 4.650202
#> [11,] 4.345679 4.460729
#> [12,] 4.657407 4.619433
#> [13,] 4.560957 4.579757
#> [14,] 4.459105 4.157085
#> [15,] 4.224537 4.129555
#> [16,] 4.479167 4.604049
#> GATGAGGCAAGTTCTG-500.1.1 GATGCTAAGAGTACCG-500.1.1
#> [1,] 4.652321 4.798055
#> [2,] 3.987342 4.391922
#> [3,] 4.341772 4.047120
#> [4,] 4.302110 4.026178
#> [5,] 4.562869 4.647719
#> [6,] 4.585654 4.273747
#> [7,] 4.042194 4.299177
#> [8,] 5.157806 5.068811
#> [9,] 4.744304 4.717277
#> [10,] 4.612658 4.447270
#> [11,] 4.350211 4.258040
#> [12,] 4.536709 4.281227
#> [13,] 4.664135 4.841436
#> [14,] 4.663291 4.525056
#> [15,] 4.400000 4.119671
#> [16,] 4.385654 4.568437
#> GATGCTAGTCAACATC-500.1.1 GATGCTATCCCATTAT-500.1.1
#> [1,] 4.228571 4.659344
#> [2,] 4.004082 4.473152
#> [3,] 4.485714 4.140167
#> [4,] 4.134694 4.322873
#> [5,] 4.643537 4.461646
#> [6,] 4.663946 4.209205
#> [7,] 4.359184 4.356695
#> [8,] 4.989116 4.966876
#> [9,] 4.571429 4.679568
#> [10,] 4.429932 4.133194
#> [11,] 4.713605 4.221409
#> [12,] 4.757823 4.384937
#> [13,] 4.212925 4.788703
#> [14,] 4.112925 4.339958
#> [15,] 4.206803 4.235007
#> [16,] 4.362585 4.128312
#> GATTCAGAGCACCGTC-500.1.1 GCAAACTCAATGAAAC-500.1.1
#> [1,] 4.581798 4.264241
#> [2,] 4.257855 4.373418
#> [3,] 4.144095 4.515295
#> [4,] 4.068256 4.284283
#> [5,] 4.393283 4.638186
#> [6,] 4.382449 4.349156
#> [7,] 4.199350 4.152954
#> [8,] 5.005417 4.758966
#> [9,] 4.748646 4.709388
#> [10,] 4.406284 4.343354
#> [11,] 4.164680 4.245781
#> [12,] 4.536295 4.327532
#> [13,] 4.837486 4.389241
#> [14,] 4.429036 4.327532
#> [15,] 4.150596 4.077004
#> [16,] 4.568797 4.792194
#> GCAAACTCATGGATGG-500.1.1 GCAAACTTCACCTCGT-500.1.1
#> [1,] 4.758065 4.324653
#> [2,] 3.789082 4.439236
#> [3,] 3.993797 4.425347
#> [4,] 4.213400 4.550347
#> [5,] 4.585608 4.330729
#> [6,] 4.024814 4.320312
#> [7,] 3.893300 4.161458
#> [8,] 5.012407 4.873264
#> [9,] 4.605459 4.697049
#> [10,] 4.004963 4.472222
#> [11,] 3.782878 4.260417
#> [12,] 4.506203 4.335937
#> [13,] 4.621588 4.513889
#> [14,] 4.124069 4.612847
#> [15,] 3.827543 4.082465
#> [16,] 4.275434 4.424479
#> GCAATCACAGATTGCT-500.1.1 GCACATATCGGCGCAT-500.1.1
#> [1,] 4.260260 4.121604
#> [2,] 4.458458 4.088400
#> [3,] 3.945946 4.341095
#> [4,] 3.806807 4.227253
#> [5,] 4.570571 4.739974
#> [6,] 4.088088 4.547219
#> [7,] 4.201201 4.051315
#> [8,] 4.466466 5.024148
#> [9,] 4.458458 4.956447
#> [10,] 4.172172 4.393273
#> [11,] 4.281281 4.489866
#> [12,] 4.524525 4.542475
#> [13,] 4.642643 4.352307
#> [14,] 4.178178 4.534713
#> [15,] 3.980981 4.080207
#> [16,] 4.866867 4.575248
#> GCACTCTAGCGTGTCC-500.1.1 GCACTCTGTAAGGATT-500.1.1
#> [1,] 4.293651 4.470243
#> [2,] 4.215420 4.153395
#> [3,] 4.069161 4.262364
#> [4,] 3.963719 4.127410
#> [5,] 4.532880 4.509640
#> [6,] 4.358277 4.230511
#> [7,] 4.277778 4.239732
#> [8,] 4.896825 5.136630
#> [9,] 4.843537 4.610226
#> [10,] 4.425170 4.462699
#> [11,] 4.475057 4.575021
#> [12,] 4.520408 4.388097
#> [13,] 5.401361 4.524728
#> [14,] 4.420635 4.083822
#> [15,] 3.806122 3.966471
#> [16,] 4.175737 4.132439
#> GCACTCTGTATAGGGC-500.1.1 GCACTCTGTCCATCCT-500.1.1
#> [1,] 4.369816 4.232558
#> [2,] 4.333787 4.148579
#> [3,] 4.285520 4.453488
#> [4,] 4.590075 4.239018
#> [5,] 4.585996 4.386305
#> [6,] 4.300476 4.462532
#> [7,] 4.540449 4.002584
#> [8,] 4.679810 4.860465
#> [9,] 4.503739 4.698966
#> [10,] 4.421482 4.290698
#> [11,] 4.271924 4.198966
#> [12,] 4.392250 4.598191
#> [13,] 4.624745 4.260982
#> [14,] 4.153637 4.364341
#> [15,] 4.362339 4.246770
#> [16,] 4.409925 4.573643
#> GCACTCTGTTCGTTGA-500.1.1 GCACTCTTCGGAATCT-500.1.1
#> [1,] 4.543269 4.364301
#> [2,] 4.268544 4.199707
#> [3,] 4.466346 4.130944
#> [4,] 4.162775 4.052670
#> [5,] 4.726648 4.678127
#> [6,] 4.388049 4.257498
#> [7,] 4.062500 4.209949
#> [8,] 4.921016 4.805413
#> [9,] 4.824176 4.903438
#> [10,] 4.215659 4.724214
#> [11,] 4.416896 4.079005
#> [12,] 4.535027 4.487198
#> [13,] 4.725962 4.681053
#> [14,] 3.977335 4.400878
#> [15,] 4.103022 4.454279
#> [16,] 4.699863 4.459400
#> GCACTCTTCGTCCGTT-500.1.1 GCAGTTAGTACTCAAC-500.1.1
#> [1,] 4.836386 4.465989
#> [2,] 4.355311 4.322909
#> [3,] 4.296703 4.311962
#> [4,] 4.398046 4.362002
#> [5,] 4.500611 4.390930
#> [6,] 4.286935 4.422205
#> [7,] 3.942613 4.114152
#> [8,] 5.068376 4.819390
#> [9,] 5.235653 4.618452
#> [10,] 4.505495 4.696638
#> [11,] 4.378510 4.232995
#> [12,] 4.847375 4.245504
#> [13,] 4.937729 4.612979
#> [14,] 4.568987 4.426114
#> [15,] 3.965812 4.110242
#> [16,] 4.805861 4.401095
#> GCATACAAGGTAGCTG-500.1.1 GCATACATCCGTCATC-500.1.1
#> [1,] 4.361746 4.523108
#> [2,] 3.874220 4.200268
#> [3,] 4.586279 4.128600
#> [4,] 3.834719 4.423979
#> [5,] 4.936590 4.813798
#> [6,] 5.113306 4.327528
#> [7,] 4.252599 4.236437
#> [8,] 4.502079 4.886805
#> [9,] 4.418919 4.690556
#> [10,] 4.069647 4.380442
#> [11,] 4.556133 4.409913
#> [12,] 4.116424 4.377763
#> [13,] 3.958420 4.815137
#> [14,] 4.719335 4.174816
#> [15,] 4.610187 4.361018
#> [16,] 4.731809 4.489618
#> GCATGATAGAGGGATA-500.1.1 GCATGATAGTAGGCCA-500.1.1
#> [1,] 4.507214 4.676277
#> [2,] 4.556049 3.939456
#> [3,] 4.146504 4.585667
#> [4,] 3.964484 4.241351
#> [5,] 4.599334 4.556013
#> [6,] 4.208657 4.966639
#> [7,] 4.423973 4.188633
#> [8,] 4.619312 4.622735
#> [9,] 5.100999 4.739292
#> [10,] 4.394007 4.857496
#> [11,] 4.538291 4.643328
#> [12,] 4.821310 4.436573
#> [13,] 4.988901 4.081549
#> [14,] 4.051054 4.521417
#> [15,] 4.584906 4.297776
#> [16,] 4.386238 4.375206
#> GCCTCTACATGCCTAA-500.1.1 GCGCAACCAGGCTCAC-500.1.1
#> [1,] 4.070034 4.377778
#> [2,] 4.730195 4.093827
#> [3,] 4.472445 4.002469
#> [4,] 4.401263 3.839506
#> [5,] 4.052239 4.745679
#> [6,] 4.194604 4.307407
#> [7,] 3.973594 4.087654
#> [8,] 4.911596 5.190123
#> [9,] 5.256602 4.744444
#> [10,] 4.904707 4.498765
#> [11,] 4.180253 4.091358
#> [12,] 3.990241 4.092593
#> [13,] 4.594145 4.341975
#> [14,] 4.605626 4.402469
#> [15,] 4.835821 3.946914
#> [16,] 4.093571 4.209877
#> GCGCAACGTTTGTGTG-500.1.1 GCGCGATAGGACCACA-500.1.1
#> [1,] 4.067642 4.419517
#> [2,] 4.265082 4.397384
#> [3,] 4.444241 4.011066
#> [4,] 4.796161 4.248491
#> [5,] 4.404936 4.656942
#> [6,] 4.326325 4.391348
#> [7,] 4.105119 4.470825
#> [8,] 4.640768 5.039235
#> [9,] 4.924132 4.688129
#> [10,] 4.363803 4.316901
#> [11,] 4.138940 3.997988
#> [12,] 4.252285 4.352113
#> [13,] 4.599634 4.332998
#> [14,] 4.822669 4.344064
#> [15,] 4.081353 4.198189
#> [16,] 4.564899 4.607646
#> GCGCGATCAAGTTCTG-500.1.1 GCGCGATCAGGTTTCA-500.1.1
#> [1,] 4.461570 4.968338
#> [2,] 4.342416 4.183377
#> [3,] 4.179748 4.087071
#> [4,] 4.323302 4.633245
#> [5,] 4.533957 4.740106
#> [6,] 4.445710 4.186016
#> [7,] 4.328589 4.083113
#> [8,] 4.867832 5.225594
#> [9,] 4.880439 5.349604
#> [10,] 4.443270 4.121372
#> [11,] 4.356649 4.073879
#> [12,] 4.300122 4.522427
#> [13,] 4.799512 5.160950
#> [14,] 4.074014 4.216359
#> [15,] 4.122001 4.083113
#> [16,] 4.451810 4.758575
#> GCGCGATCATAGGATA-500.1.1 GCGCGATTCCTATTCA-500.1.1
#> [1,] 4.591236 4.443320
#> [2,] 4.229562 4.361336
#> [3,] 4.306736 4.294534
#> [4,] 4.268149 4.073887
#> [5,] 4.803139 4.401822
#> [6,] 4.537606 4.591093
#> [7,] 3.980379 4.410931
#> [8,] 5.157619 5.064777
#> [9,] 5.158927 4.543522
#> [10,] 4.312623 4.260121
#> [11,] 4.408764 3.972672
#> [12,] 4.206671 4.397773
#> [13,] 4.608895 4.398785
#> [14,] 4.563113 4.147773
#> [15,] 4.062786 4.101215
#> [16,] 4.659908 4.641700
#> GCGGGTTGTTAAAGAC-500.1.1 GCTCCTAAGGAGTCTG-500.1.1
#> [1,] 4.443534 4.403846
#> [2,] 4.222222 4.328895
#> [3,] 4.477231 4.170118
#> [4,] 4.555556 3.996548
#> [5,] 4.291439 4.528107
#> [6,] 4.526412 4.339250
#> [7,] 4.438069 4.185404
#> [8,] 4.595628 4.839250
#> [9,] 4.759563 4.629191
#> [10,] 4.501821 4.291420
#> [11,] 4.347905 4.370316
#> [12,] 4.303279 4.346154
#> [13,] 4.622040 4.617357
#> [14,] 4.328780 4.227318
#> [15,] 4.241348 3.952663
#> [16,] 4.408925 4.510355
#> GCTCCTACAAGTAATG-500.1.1 GCTCTGTAGGATGGTC-500.1.1
#> [1,] 4.647740 4.449606
#> [2,] 4.192352 4.334794
#> [3,] 4.410197 4.036810
#> [4,] 4.662804 4.085013
#> [5,] 4.732329 4.586328
#> [6,] 4.207416 4.203330
#> [7,] 4.229432 4.303243
#> [8,] 4.950174 5.015776
#> [9,] 4.862109 4.783523
#> [10,] 4.405562 4.491674
#> [11,] 4.056779 4.366345
#> [12,] 4.763615 4.345311
#> [13,] 4.666280 4.507450
#> [14,] 4.396292 4.496933
#> [15,] 3.932793 4.370727
#> [16,] 4.585168 4.379492
#> GCTCTGTAGTTGTCGT-500.1.1 GCTGCGACAGCGAACA-500.1.1
#> [1,] 4.282916 4.128118
#> [2,] 4.139282 4.238662
#> [3,] 4.362350 4.181406
#> [4,] 4.298150 4.225624
#> [5,] 4.344940 4.866213
#> [6,] 4.206746 4.281179
#> [7,] 4.140370 4.492063
#> [8,] 4.540805 4.774376
#> [9,] 4.693145 4.502834
#> [10,] 4.413493 4.358844
#> [11,] 4.149075 4.137755
#> [12,] 4.442873 4.229592
#> [13,] 4.285092 4.479592
#> [14,] 4.127312 4.287415
#> [15,] 4.092492 3.915533
#> [16,] 4.584331 4.350907
#> GCTGCGATCACGCGGT-500.1.1 GCTGGGTCAAGACGTG-500.1.1
#> [1,] 4.678468 4.536481
#> [2,] 4.317197 4.218884
#> [3,] 4.286127 4.539342
#> [4,] 4.422688 4.247496
#> [5,] 4.393786 4.467096
#> [6,] 4.685694 4.225322
#> [7,] 4.193642 4.275393
#> [8,] 4.819364 4.877682
#> [9,] 4.703035 4.533619
#> [10,] 4.255780 4.223176
#> [11,] 4.235549 4.490701
#> [12,] 4.593931 4.454220
#> [13,] 4.655347 4.306152
#> [14,] 4.498555 4.160229
#> [15,] 4.283960 4.171674
#> [16,] 4.232659 4.351216
#> GCTGGGTCACACAGAG-500.1.1 GCTGGGTTCGCGGATC-500.1.1
#> [1,] 4.309109 4.315223
#> [2,] 4.254845 4.312660
#> [3,] 4.503391 4.477704
#> [4,] 4.322674 4.386468
#> [5,] 4.633721 4.660174
#> [6,] 4.609012 4.422348
#> [7,] 4.384205 4.001538
#> [8,] 4.870640 5.043055
#> [9,] 4.761628 4.971297
#> [10,] 4.567345 4.331625
#> [11,] 4.419574 4.496156
#> [12,] 4.510659 4.358790
#> [13,] 4.218508 4.397232
#> [14,] 4.269864 4.386468
#> [15,] 4.156492 4.172732
#> [16,] 4.598837 4.716043
#> GCTTGAAAGTGGAGTC-500.1.1 GCTTGAAAGTGGTCCC-500.1.1
#> [1,] 4.541328 4.796399
#> [2,] 4.570461 4.537396
#> [3,] 4.487805 4.123269
#> [4,] 4.493902 3.900277
#> [5,] 4.207995 4.454294
#> [6,] 4.346883 4.156510
#> [7,] 4.191057 3.907202
#> [8,] 5.029133 5.314404
#> [9,] 4.934282 4.843490
#> [10,] 4.289973 4.152355
#> [11,] 4.313686 4.170360
#> [12,] 4.737127 4.367036
#> [13,] 4.375339 5.156510
#> [14,] 4.595528 4.396122
#> [15,] 4.348238 4.037396
#> [16,] 4.629404 4.534626
#> GCTTGAAGTGAGTATA-500.1.1 GCTTGAAGTTGCGCAC-500.1.1
#> [1,] 4.312259 4.658733
#> [2,] 4.304549 4.131505
#> [3,] 4.700077 4.210165
#> [4,] 4.600617 4.473175
#> [5,] 4.654588 4.534490
#> [6,] 4.619121 4.469141
#> [7,] 4.359291 4.350141
#> [8,] 4.908250 4.816055
#> [9,] 4.782575 4.391287
#> [10,] 4.505012 4.270674
#> [11,] 4.420971 4.289230
#> [12,] 4.563608 4.460266
#> [13,] 4.309175 4.622832
#> [14,] 4.195066 4.202904
#> [15,] 4.299923 4.260589
#> [16,] 4.494988 4.446954
#> GCTTGAATCCGTAGTA-500.1.1 GGAAAGCAGTCTCGGC-500.1.1
#> [1,] 4.341209 4.405769
#> [2,] 4.234885 4.566026
#> [3,] 4.394024 4.275000
#> [4,] 4.198054 4.352564
#> [5,] 4.469771 4.400000
#> [6,] 4.462126 4.427564
#> [7,] 4.184851 4.387821
#> [8,] 4.932592 4.822436
#> [9,] 4.699097 4.734615
#> [10,] 4.610146 4.546795
#> [11,] 4.378040 4.258333
#> [12,] 4.599027 4.612821
#> [13,] 4.542043 4.705128
#> [14,] 4.186240 4.173077
#> [15,] 4.024322 4.417308
#> [16,] 4.580959 4.333333
#> GGAAAGCCAATCTGCA-500.1.1 GGAAAGCGTGCCTGCA-500.1.1
#> [1,] 4.323820 4.282367
#> [2,] 4.194503 4.409371
#> [3,] 4.203312 4.288533
#> [4,] 4.355532 3.988903
#> [5,] 4.774489 4.549938
#> [6,] 4.554616 4.143033
#> [7,] 3.868217 3.902589
#> [8,] 5.035588 5.404439
#> [9,] 5.132488 5.260173
#> [10,] 4.480268 4.202219
#> [11,] 4.382664 4.149199
#> [12,] 4.531712 4.282367
#> [13,] 4.451022 4.283600
#> [14,] 4.278365 4.294698
#> [15,] 3.955955 3.625154
#> [16,] 4.295278 4.133169
#> GGAAAGCTCGGTCCGA-500.1.1 GGAACTTTCATCTGTT-500.1.1
#> [1,] 4.646274 4.298091
#> [2,] 4.459399 4.293686
#> [3,] 3.959399 4.613069
#> [4,] 4.313682 4.522761
#> [5,] 4.632925 4.553598
#> [6,] 4.448276 4.141703
#> [7,] 4.182981 4.466960
#> [8,] 4.853170 5.245228
#> [9,] 4.557286 4.783407
#> [10,] 4.557842 4.240088
#> [11,] 4.355951 4.364170
#> [12,] 4.345940 4.654185
#> [13,] 4.733593 4.121880
#> [14,] 4.434928 4.331865
#> [15,] 3.909344 4.518355
#> [16,] 4.157953 4.193098
#> GGACAAGGTTACGACT-500.1.1 GGACAAGTCCAAATGC-500.1.1
#> [1,] 4.365372 4.304462
#> [2,] 4.325153 4.417323
#> [3,] 4.204499 3.951444
#> [4,] 4.366735 4.337270
#> [5,] 4.566462 4.502625
#> [6,] 4.237219 4.435696
#> [7,] 4.424676 4.552493
#> [8,] 4.800954 4.803150
#> [9,] 4.603272 4.217848
#> [10,] 4.414451 4.286089
#> [11,] 4.441718 4.245407
#> [12,] 4.436946 4.566929
#> [13,] 4.553511 4.253281
#> [14,] 4.267894 4.387139
#> [15,] 4.230402 4.391076
#> [16,] 4.631220 4.580052
#> GGACAGATCCGTTGCT-500.1.1 GGACATTAGCGATAGC-500.1.1
#> [1,] 4.826495 4.347195
#> [2,] 4.434936 4.611219
#> [3,] 4.449004 4.034816
#> [4,] 4.528722 3.888781
#> [5,] 4.777257 4.443907
#> [6,] 4.382181 3.913926
#> [7,] 4.117233 3.826886
#> [8,] 5.375147 5.186654
#> [9,] 4.695193 4.330754
#> [10,] 4.308324 4.380077
#> [11,] 4.247362 4.322050
#> [12,] 4.478312 3.977756
#> [13,] 4.506448 4.716634
#> [14,] 4.337632 4.060928
#> [15,] 4.092614 4.344294
#> [16,] 4.493552 4.510638
#> GGACATTTCAGTGCAT-500.1.1 GGACATTTCGTTTGCC-500.1.1
#> [1,] 4.262229 4.476407
#> [2,] 4.207262 4.529847
#> [3,] 4.468482 4.291643
#> [4,] 4.626324 4.306993
#> [5,] 4.659607 4.601478
#> [6,] 4.354513 4.345082
#> [7,] 3.806354 4.441160
#> [8,] 5.131619 4.944287
#> [9,] 5.272819 4.561683
#> [10,] 4.483106 4.359295
#> [11,] 4.259708 4.238204
#> [12,] 4.270298 4.843093
#> [13,] 4.543621 4.847072
#> [14,] 4.367625 4.329164
#> [15,] 3.972769 4.644684
#> [16,] 4.759455 4.590677
#> GGACGTCGTGCTGTAT-500.1.1 GGACGTCTCTAGCACA-500.1.1
#> [1,] 4.496063 4.629870
#> [2,] 4.273341 4.198864
#> [3,] 4.472441 4.399351
#> [4,] 4.489314 4.228896
#> [5,] 4.628796 4.789773
#> [6,] 4.601800 4.593344
#> [7,] 4.303712 4.243506
#> [8,] 5.174353 5.293019
#> [9,] 4.839145 5.017857
#> [10,] 4.487064 4.200487
#> [11,] 4.422947 4.198864
#> [12,] 4.314961 4.475649
#> [13,] 4.352081 4.981331
#> [14,] 4.443195 4.023539
#> [15,] 4.278965 3.987825
#> [16,] 4.458943 4.418019
#> GGATTACTCTTAGCCC-500.1.1 GGCGACTAGGTAGCCA-500.1.1
#> [1,] 5.041489 4.282238
#> [2,] 4.190426 4.082725
#> [3,] 4.139362 4.145985
#> [4,] 4.090426 4.206813
#> [5,] 4.680851 4.283455
#> [6,] 4.376596 4.510949
#> [7,] 4.046809 4.381995
#> [8,] 4.732979 4.975669
#> [9,] 5.080851 4.624088
#> [10,] 4.015957 4.357664
#> [11,] 3.928723 4.317518
#> [12,] 4.574468 4.159367
#> [13,] 5.286170 4.411192
#> [14,] 4.235106 4.356448
#> [15,] 4.069149 4.121655
#> [16,] 4.618085 4.690998
#> GGCGACTTCTTCGGTC-500.1.1 GGCTCGATCAATAAGG-500.1.1
#> [1,] 4.439240 4.369406
#> [2,] 4.577054 4.248169
#> [3,] 4.557366 4.411717
#> [4,] 4.245078 4.458096
#> [5,] 4.461643 4.314076
#> [6,] 4.349627 4.344182
#> [7,] 4.061100 4.319772
#> [8,] 4.799728 4.866558
#> [9,] 5.043449 4.638731
#> [10,] 4.530210 4.435313
#> [11,] 4.637475 4.328723
#> [12,] 4.349627 4.391375
#> [13,] 4.340122 4.490643
#> [14,] 4.522743 4.796583
#> [15,] 4.319756 4.384866
#> [16,] 4.819416 4.257933
#> GGCTGGTAGCCACGTC-500.1.1 GGCTGGTAGCGATATA-500.1.1
#> [1,] 3.969532 4.376177
#> [2,] 4.356910 4.013217
#> [3,] 4.473341 4.062779
#> [4,] 3.985854 4.305964
#> [5,] 4.498368 4.643483
#> [6,] 4.255713 4.109532
#> [7,] 3.930359 4.357839
#> [8,] 4.651795 4.566661
#> [9,] 4.460283 4.403602
#> [10,] 4.278564 4.030563
#> [11,] 4.285092 4.076161
#> [12,] 4.819369 4.375847
#> [13,] 4.389554 4.348753
#> [14,] 4.107726 4.169503
#> [15,] 4.140370 4.140096
#> [16,] 4.682263 4.356187
#> GGGAATGCACCGAATT-500.1.1 GGGACCTAGATCCCGC-500.1.1
#> [1,] 4.217900 4.688255
#> [2,] 4.269880 4.050494
#> [3,] 4.176936 4.059276
#> [4,] 4.702582 3.978046
#> [5,] 4.511876 4.284303
#> [6,] 4.176936 4.167947
#> [7,] 3.973838 4.051592
#> [8,] 5.425129 4.745335
#> [9,] 5.086403 4.687157
#> [10,] 4.183477 4.082327
#> [11,] 4.269880 4.043908
#> [12,] 4.166609 4.433589
#> [13,] 4.256454 4.452250
#> [14,] 4.292943 4.245884
#> [15,] 4.060585 4.197585
#> [16,] 4.424785 4.454446
#> GGGACCTGTGGGTCAA-500.1.1 GGGACCTTCTACTATC-500.1.1
#> [1,] 4.474678 4.226625
#> [2,] 3.784549 4.167854
#> [3,] 3.955365 4.386465
#> [4,] 4.146781 4.392253
#> [5,] 4.262661 4.553428
#> [6,] 5.056652 4.647818
#> [7,] 3.997425 4.371327
#> [8,] 4.739914 4.782280
#> [9,] 4.378541 4.550757
#> [10,] 4.140773 4.435886
#> [11,] 4.010300 4.369101
#> [12,] 3.996567 4.492876
#> [13,] 4.442060 4.170525
#> [14,] 4.875536 4.459038
#> [15,] 4.074678 4.319679
#> [16,] 4.944206 4.363313
#> GGGAGATAGTAGGCCA-500.1.1 GGGAGATCATGCCCGA-500.1.1
#> [1,] 4.438023 4.381625
#> [2,] 4.368821 4.333922
#> [3,] 4.583270 4.131625
#> [4,] 4.345247 4.339223
#> [5,] 4.412167 4.328622
#> [6,] 4.695057 4.415194
#> [7,] 4.301901 4.343640
#> [8,] 4.752091 4.839223
#> [9,] 4.858555 4.599823
#> [10,] 4.412167 4.658127
#> [11,] 4.228137 4.302120
#> [12,] 4.526236 4.637809
#> [13,] 4.419011 4.598940
#> [14,] 4.313308 4.642226
#> [15,] 4.216730 4.424912
#> [16,] 4.713308 4.721731
#> GGGCACTGTTACGCGC-500.1.1 GGGCATCGTCCGAACC-500.1.1
#> [1,] 4.378596 4.529677
#> [2,] 4.298596 4.371150
#> [3,] 4.254971 4.208114
#> [4,] 4.135439 4.338843
#> [5,] 4.591696 4.689707
#> [6,] 4.264795 4.166792
#> [7,] 4.330292 4.148760
#> [8,] 4.781053 4.996995
#> [9,] 4.598947 4.712246
#> [10,] 4.255205 4.309542
#> [11,] 4.305146 4.329076
#> [12,] 4.594620 4.348610
#> [13,] 4.489240 4.765590
#> [14,] 4.249942 4.050338
#> [15,] 4.258596 4.068370
#> [16,] 4.553801 4.492111
#> GGGTTGCAGGTAGCCA-500.1.1 GGGTTGCCATCAGTAC-500.1.1
#> [1,] 4.385078 4.761141
#> [2,] 4.410349 4.416221
#> [3,] 4.452467 4.234403
#> [4,] 4.172082 4.106061
#> [5,] 4.204573 4.368093
#> [6,] 4.334537 4.463458
#> [7,] 4.097473 4.224599
#> [8,] 4.598075 4.666667
#> [9,] 3.886883 4.789661
#> [10,] 4.415162 4.542781
#> [11,] 4.137184 4.045455
#> [12,] 4.628159 4.235294
#> [13,] 4.246691 4.872549
#> [14,] 4.316486 4.269162
#> [15,] 4.664260 4.141711
#> [16,] 4.631769 4.540998
#> GGGTTGCGTAGAGTGC-500.1.1 GGGTTGCTCCCTCAGT-500.1.1
#> [1,] 4.281822 4.316399
#> [2,] 4.193850 4.213012
#> [3,] 4.422733 4.231729
#> [4,] 4.227715 4.476827
#> [5,] 4.318801 4.457219
#> [6,] 4.399766 4.355615
#> [7,] 4.248346 4.099822
#> [8,] 4.917088 4.794118
#> [9,] 4.717400 4.587344
#> [10,] 4.576878 4.339572
#> [11,] 4.535617 4.135472
#> [12,] 4.676139 4.525847
#> [13,] 4.321137 4.306595
#> [14,] 4.147917 4.430481
#> [15,] 4.108213 4.103387
#> [16,] 4.462826 4.704100
#> GGGTTGCTCTGCAGTA-500.1.1 GGTATTGCATGTTCCC-500.1.1
#> [1,] 4.418946 4.304049
#> [2,] 4.567712 4.232238
#> [3,] 4.251501 4.431627
#> [4,] 4.342228 4.303285
#> [5,] 4.452969 4.728037
#> [6,] 4.434957 4.364400
#> [7,] 3.926618 3.964859
#> [8,] 5.049366 5.011459
#> [9,] 4.741161 4.961803
#> [10,] 4.518346 4.126814
#> [11,] 4.360240 4.340718
#> [12,] 4.508339 4.666921
#> [13,] 4.404270 4.618029
#> [14,] 4.392929 3.975554
#> [15,] 4.203469 3.941176
#> [16,] 4.440294 4.566845
#> GGTATTGGTGCACTTA-500.1.1 GGTATTGTCAGGATCT-500.1.1
#> [1,] 4.258776 4.395976
#> [2,] 4.814443 4.059372
#> [3,] 4.338014 4.199215
#> [4,] 4.362086 4.347399
#> [5,] 4.070712 4.875368
#> [6,] 4.086259 4.117272
#> [7,] 3.992477 4.241413
#> [8,] 4.600301 4.639352
#> [9,] 5.184554 4.340530
#> [10,] 5.051655 4.208047
#> [11,] 4.222668 4.103533
#> [12,] 4.289870 4.197743
#> [13,] 4.419759 4.570167
#> [14,] 4.379639 4.134446
#> [15,] 4.972919 4.079980
#> [16,] 4.241224 4.287046
#> GGTGAAGCAGTTAACC-500.1.1 GGTGCGTCATAGTAAG-500.1.1
#> [1,] 4.029586 4.820829
#> [2,] 4.112426 3.982083
#> [3,] 4.306509 4.025756
#> [4,] 4.143195 4.386338
#> [5,] 4.662722 4.601344
#> [6,] 4.229586 4.230683
#> [7,] 4.460355 4.180291
#> [8,] 4.454438 5.222844
#> [9,] 3.997633 4.295633
#> [10,] 4.459172 4.034714
#> [11,] 4.510059 4.054871
#> [12,] 4.463905 3.960806
#> [13,] 4.313609 4.427772
#> [14,] 4.139645 4.082867
#> [15,] 3.906509 4.206047
#> [16,] 4.576331 4.344905
#> GGTGTTATCAGGATCT-500.1.1 GTAACTGGTTCTGTTT-500.1.1
#> [1,] 4.406452 4.706512
#> [2,] 4.089826 4.264942
#> [3,] 4.388586 4.373773
#> [4,] 4.367246 4.288136
#> [5,] 4.536973 4.874219
#> [6,] 4.573201 4.106155
#> [7,] 4.182630 4.422837
#> [8,] 4.767742 4.512935
#> [9,] 4.713648 4.110616
#> [10,] 4.530521 4.422837
#> [11,] 4.454591 4.151650
#> [12,] 4.523077 4.002676
#> [13,] 4.203970 4.269402
#> [14,] 4.677419 4.273863
#> [15,] 4.449132 4.293488
#> [16,] 4.226303 4.369313
#> GTACTCCGTCCCTACT-500.1.1 GTACTTTGTAGAGCTG-500.1.1
#> [1,] 4.466895 4.366228
#> [2,] 4.479452 4.247807
#> [3,] 4.303653 4.355811
#> [4,] 4.430365 4.359649
#> [5,] 4.360731 4.694627
#> [6,] 4.328767 4.271930
#> [7,] 3.962900 4.014254
#> [8,] 5.130708 4.862390
#> [9,] 4.839041 4.936404
#> [10,] 4.301370 4.200658
#> [11,] 4.343037 4.475877
#> [12,] 4.418379 4.251645
#> [13,] 4.541096 4.571820
#> [14,] 4.562785 4.318531
#> [15,] 4.117009 4.216009
#> [16,] 4.498288 4.562500
#> GTACTTTGTCAGGACA-500.1.1 GTACTTTGTTATCCGA-500.1.1
#> [1,] 4.506073 4.157843
#> [2,] 4.218623 4.410784
#> [3,] 4.156275 4.218627
#> [4,] 4.429150 4.679412
#> [5,] 4.198381 4.592157
#> [6,] 4.421053 4.347059
#> [7,] 4.232389 4.214706
#> [8,] 5.089069 4.753922
#> [9,] 5.082591 4.516667
#> [10,] 4.538462 4.300000
#> [11,] 4.338462 4.291176
#> [12,] 4.412955 4.328431
#> [13,] 4.382186 4.428431
#> [14,] 5.165992 4.187255
#> [15,] 4.277733 4.086275
#> [16,] 4.587045 4.776471
#> GTAGTCACAAGCGAGT-500.1.1 GTATTCTTCTGCAGTA-500.1.1
#> [1,] 4.224357 4.490312
#> [2,] 4.154021 4.185222
#> [3,] 4.484533 4.336946
#> [4,] 4.525562 4.352709
#> [5,] 4.716053 4.616420
#> [6,] 4.473136 4.443350
#> [7,] 4.090850 4.146470
#> [8,] 4.859655 5.013465
#> [9,] 4.881472 4.874548
#> [10,] 4.380658 4.510345
#> [11,] 4.524259 4.527422
#> [12,] 4.353305 4.389163
#> [13,] 4.359492 4.620690
#> [14,] 4.333768 4.362562
#> [15,] 4.158580 4.077833
#> [16,] 4.766200 4.251560
#> GTCAAGTGTACTTGAC-500.1.1 GTCATTTTCTCCCTGA-500.1.1
#> [1,] 4.457244 4.682002
#> [2,] 4.346996 4.338726
#> [3,] 4.076325 4.159757
#> [4,] 4.105300 4.460061
#> [5,] 4.592933 4.540445
#> [6,] 4.255124 4.446411
#> [7,] 4.537809 4.182508
#> [8,] 4.866431 5.056117
#> [9,] 4.591519 4.860971
#> [10,] 4.248057 4.352376
#> [11,] 4.173145 4.354398
#> [12,] 4.351943 4.327604
#> [13,] 4.419788 4.729019
#> [14,] 4.132862 4.515672
#> [15,] 4.342756 4.117796
#> [16,] 4.584452 4.510111
#> GTCCTCAAGGTGCAAC-500.1.1 GTCCTCAGTAGCTCCG-500.1.1
#> [1,] 4.475871 4.767876
#> [2,] 4.309651 4.375130
#> [3,] 4.016086 4.261140
#> [4,] 4.258713 4.149223
#> [5,] 4.832440 4.674611
#> [6,] 4.348525 4.121244
#> [7,] 4.008043 4.253886
#> [8,] 4.868633 4.909845
#> [9,] 4.410188 5.191710
#> [10,] 4.396783 4.125389
#> [11,] 4.332440 4.204145
#> [12,] 4.579088 4.524352
#> [13,] 4.817694 4.977202
#> [14,] 4.258713 4.224870
#> [15,] 4.128686 4.137824
#> [16,] 4.353887 4.887047
#> GTCCTCAGTTGCCTCT-500.1.1 GTCGGGTCACGCTTTC-500.1.1
#> [1,] 4.169376 4.269127
#> [2,] 4.326775 4.952295
#> [3,] 4.100086 3.924392
#> [4,] 4.129170 4.439244
#> [5,] 4.836612 4.482448
#> [6,] 4.393499 4.583258
#> [7,] 4.116339 4.280828
#> [8,] 4.803251 5.096310
#> [9,] 4.727117 4.243924
#> [10,] 4.195894 4.602160
#> [11,] 4.217280 4.443744
#> [12,] 4.740804 4.465347
#> [13,] 4.962361 4.648065
#> [14,] 4.094098 4.343834
#> [15,] 3.988879 3.680468
#> [16,] 4.792130 4.428443
#> GTCGTAACATCCTTGC-500.1.1 GTCTCGTTCTTGAGGT-500.1.1
#> [1,] 4.478196 4.501777
#> [2,] 4.210109 4.439232
#> [3,] 4.522795 4.361763
#> [4,] 4.236373 4.392324
#> [5,] 4.882557 4.316276
#> [6,] 4.739841 4.581379
#> [7,] 4.310704 4.248045
#> [8,] 4.943013 5.238095
#> [9,] 4.662537 4.742715
#> [10,] 4.488603 4.670220
#> [11,] 4.736373 4.461976
#> [12,] 4.274034 4.436389
#> [13,] 4.111001 4.254442
#> [14,] 4.782458 4.437811
#> [15,] 4.472745 4.511016
#> [16,] 4.456392 4.366738
#> GTCTTCGTCGCTGATA-500.1.1 GTGAAGGGTTATTCTC-500.1.1
#> [1,] 4.217348 4.399452
#> [2,] 4.243270 4.552102
#> [3,] 4.109671 4.428702
#> [4,] 4.153539 4.258684
#> [5,] 4.578265 4.607861
#> [6,] 4.145563 4.498172
#> [7,] 4.305085 4.344607
#> [8,] 5.006979 4.922303
#> [9,] 4.832502 4.579525
#> [10,] 4.507478 4.411335
#> [11,] 4.358923 4.369287
#> [12,] 4.588235 4.521024
#> [13,] 4.825523 4.780622
#> [14,] 4.340977 4.106947
#> [15,] 3.995015 4.520110
#> [16,] 4.728814 4.731261
#> GTGCAGCGTGACGCCT-500.1.1 GTGCAGCTCGTTACGA-500.1.1
#> [1,] 4.097950 4.377320
#> [2,] 4.175399 4.371134
#> [3,] 4.176917 4.362887
#> [4,] 4.880030 4.539519
#> [5,] 4.217920 4.592440
#> [6,] 4.410023 4.403436
#> [7,] 4.579347 4.556014
#> [8,] 4.679575 4.736770
#> [9,] 4.616553 4.474914
#> [10,] 4.111617 4.526460
#> [11,] 4.393318 4.676289
#> [12,] 4.599848 4.711340
#> [13,] 4.584662 4.296907
#> [14,] 4.800304 4.473540
#> [15,] 4.326500 4.422680
#> [16,] 3.999241 4.528522
#> GTGCATATCTCGGACG-500.1.1 GTGCTTCGTGATAAAC-500.1.1
#> [1,] 4.504921 4.552217
#> [2,] 4.403543 4.351931
#> [3,] 4.319882 4.118026
#> [4,] 4.196850 4.428469
#> [5,] 4.557087 4.555079
#> [6,] 4.483268 4.268956
#> [7,] 4.149606 4.051502
#> [8,] 4.939961 4.835479
#> [9,] 4.482283 4.913448
#> [10,] 4.333661 4.300429
#> [11,] 4.484252 4.349070
#> [12,] 4.537402 4.394134
#> [13,] 4.616142 5.034335
#> [14,] 4.480315 4.334764
#> [15,] 4.325787 4.145923
#> [16,] 4.505906 4.641631
#> GTGCTTCGTTGCGTTA-500.1.1 GTGCTTCTCCGCGTTT-500.1.1
#> [1,] 4.466594 4.310638
#> [2,] 4.294633 4.380426
#> [3,] 4.290252 4.382128
#> [4,] 4.460022 4.315745
#> [5,] 4.433735 4.452766
#> [6,] 4.376780 4.258723
#> [7,] 4.374589 4.210213
#> [8,] 4.713034 4.987234
#> [9,] 4.696605 4.651915
#> [10,] 4.131435 4.370213
#> [11,] 4.369113 4.548085
#> [12,] 4.454545 4.473191
#> [13,] 4.451260 4.714043
#> [14,] 4.872946 4.417021
#> [15,] 4.125958 4.250213
#> [16,] 4.164294 4.436596
#> GTGGGTCAGGACTGGT-500.1.1 GTGGGTCCAACACGCC-500.1.1
#> [1,] 4.591770 4.619217
#> [2,] 4.163237 4.217082
#> [3,] 4.083676 4.555160
#> [4,] 4.316872 4.669039
#> [5,] 4.688889 4.643238
#> [6,] 4.355556 4.635231
#> [7,] 4.111385 4.332740
#> [8,] 4.925926 5.049822
#> [9,] 4.780796 4.867438
#> [10,] 4.131687 4.461744
#> [11,] 4.102058 4.255338
#> [12,] 4.226886 4.685053
#> [13,] 4.837586 4.314057
#> [14,] 4.306996 4.322064
#> [15,] 4.111111 4.222420
#> [16,] 4.377229 4.223310
#> GTGGGTCTCGTTACAG-500.1.1 GTGTGCGAGGGTGTTG-500.1.1
#> [1,] 3.985646 4.501105
#> [2,] 4.364593 4.271186
#> [3,] 4.054545 4.651437
#> [4,] 4.157895 4.332351
#> [5,] 4.388517 4.910833
#> [6,] 4.120574 4.400147
#> [7,] 4.173206 3.963891
#> [8,] 5.153110 5.265291
#> [9,] 4.645933 4.840088
#> [10,] 4.169378 4.492262
#> [11,] 4.169378 4.413412
#> [12,] 4.219139 4.660280
#> [13,] 4.544498 4.712601
#> [14,] 4.532057 4.383935
#> [15,] 4.073684 4.098747
#> [16,] 4.658373 4.106853
#> GTGTTAGAGGGTCTCC-500.1.1 GTGTTAGTCAACTCTT-500.1.1
#> [1,] 4.515784 3.617878
#> [2,] 4.068486 3.947937
#> [3,] 4.641520 4.055010
#> [4,] 4.187801 4.047151
#> [5,] 4.857678 4.140472
#> [6,] 4.786517 5.347741
#> [7,] 4.168539 3.825147
#> [8,] 4.851792 4.728880
#> [9,] 4.690744 4.624754
#> [10,] 4.645800 4.257367
#> [11,] 4.490637 4.051081
#> [12,] 4.509898 4.385069
#> [13,] 4.060995 3.928291
#> [14,] 4.574639 5.411591
#> [15,] 4.491707 3.966601
#> [16,] 4.548422 4.952849
#> GTGTTAGTCGTTACGA-500.1.1 GTTAAGCAGTCAAGGC-500.1.1
#> [1,] 4.649209 4.551993
#> [2,] 4.219368 4.170866
#> [3,] 4.268775 4.035273
#> [4,] 4.509881 4.139716
#> [5,] 4.833992 4.639945
#> [6,] 4.082016 4.410902
#> [7,] 4.273715 4.244617
#> [8,] 4.884387 4.785158
#> [9,] 4.950593 4.595511
#> [10,] 4.270751 4.155291
#> [11,] 4.099802 4.256070
#> [12,] 4.882411 4.427393
#> [13,] 4.735178 4.617957
#> [14,] 4.532609 4.131012
#> [15,] 4.236166 4.136509
#> [16,] 4.597826 4.449840
#> GTTAAGCCAACGCACC-500.1.1 GTTAAGCTCACAGGCC-500.1.1
#> [1,] 4.537752 4.352265
#> [2,] 4.485738 4.201294
#> [3,] 4.306208 4.320633
#> [4,] 4.296141 4.191229
#> [5,] 4.550336 4.407620
#> [6,] 4.085570 4.282531
#> [7,] 4.339765 4.308411
#> [8,] 4.937081 4.928109
#> [9,] 4.739933 4.891445
#> [10,] 4.261745 4.771387
#> [11,] 4.352349 4.269590
#> [12,] 4.142617 4.514019
#> [13,] 5.021812 4.511862
#> [14,] 4.171141 4.883537
#> [15,] 4.120805 4.335730
#> [16,] 4.552852 4.473041
#> GTTACAGAGTGTACGG-500.1.1 TAAACCGGTCTGCGGT-500.1.1
#> [1,] 4.696408 4.620546
#> [2,] 4.117034 4.333040
#> [3,] 4.098494 4.290585
#> [4,] 4.580533 4.282226
#> [5,] 4.752028 4.598988
#> [6,] 4.239861 4.206555
#> [7,] 3.894554 4.115046
#> [8,] 4.913094 5.053454
#> [9,] 4.798378 4.744611
#> [10,] 4.198146 4.246590
#> [11,] 4.424102 4.234272
#> [12,] 4.812283 4.456885
#> [13,] 4.746234 4.791685
#> [14,] 4.314021 4.213374
#> [15,] 3.745075 4.154641
#> [16,] 4.522596 4.579410
#> TAAGAGATCCAAGCCG-500.1.1 TAAGCGTCAGTAAGAT-500.1.1
#> [1,] 4.401507 4.543357
#> [2,] 4.205597 4.085919
#> [3,] 4.414424 3.989658
#> [4,] 4.093649 4.170247
#> [5,] 4.200215 4.441527
#> [6,] 4.297094 4.464598
#> [7,] 4.087191 4.265712
#> [8,] 4.918192 5.160700
#> [9,] 4.689989 4.730310
#> [10,] 4.534984 4.147176
#> [11,] 3.820237 4.208433
#> [12,] 4.356297 4.536993
#> [13,] 4.498385 4.560064
#> [14,] 4.149623 4.385044
#> [15,] 4.159311 4.137629
#> [16,] 4.412271 4.503580
#> TAAGCGTGTAATTGGA-500.1.1 TACACGATCCACTCCA-500.1.1
#> [1,] 4.482264 4.621062
#> [2,] 4.211321 4.405941
#> [3,] 4.147925 4.472547
#> [4,] 4.486792 4.426643
#> [5,] 4.237736 4.810081
#> [6,] 4.212075 4.448245
#> [7,] 4.732075 4.404140
#> [8,] 4.749434 4.914491
#> [9,] 4.658113 4.765977
#> [10,] 4.213585 4.432943
#> [11,] 4.415094 4.125113
#> [12,] 4.387170 4.362736
#> [13,] 4.776604 5.054005
#> [14,] 3.929057 4.135014
#> [15,] 4.473208 4.368137
#> [16,] 4.500377 4.772277
#> TACAGTGAGTGTTAGA-500.1.1 TACAGTGCAACTGGCC-500.1.1
#> [1,] 4.527897 4.441737
#> [2,] 4.248927 4.138771
#> [3,] 4.326180 4.093750
#> [4,] 4.176681 4.101695
#> [5,] 4.499285 4.682733
#> [6,] 4.452790 3.981992
#> [7,] 4.325465 4.060381
#> [8,] 4.904149 4.800318
#> [9,] 4.771102 4.838453
#> [10,] 4.313305 4.346928
#> [11,] 4.361230 4.343220
#> [12,] 4.319742 4.377648
#> [13,] 4.486409 4.946504
#> [14,] 4.391989 4.021716
#> [15,] 4.122318 4.002648
#> [16,] 4.338340 4.381356
#> TACCTATTCTCGGACG-500.1.1 TACCTTAGTAGAGGAA-500.1.1
#> [1,] 4.756303 4.701158
#> [2,] 4.546218 4.210039
#> [3,] 3.956583 4.287259
#> [4,] 4.598039 3.906564
#> [5,] 4.121849 4.398456
#> [6,] 4.560224 4.513514
#> [7,] 4.324930 4.318919
#> [8,] 5.289916 4.840927
#> [9,] 4.474790 4.787645
#> [10,] 4.724090 4.199228
#> [11,] 4.462185 4.443243
#> [12,] 4.329132 4.413127
#> [13,] 4.708683 4.793050
#> [14,] 4.236695 4.034749
#> [15,] 3.656863 4.051737
#> [16,] 4.435574 4.335907
#> TACCTTAGTGGTACAG-500.1.1 TACGGTAAGAGTACAT-500.1.1
#> [1,] 4.697489 4.472103
#> [2,] 4.361872 4.482526
#> [3,] 4.255708 4.091355
#> [4,] 4.359589 4.282649
#> [5,] 4.481735 4.241570
#> [6,] 4.397260 4.648682
#> [7,] 3.921233 4.507051
#> [8,] 4.977169 4.719191
#> [9,] 4.670091 4.536481
#> [10,] 4.327626 4.759657
#> [11,] 4.186073 4.264255
#> [12,] 4.191781 4.222563
#> [13,] 5.188356 4.503985
#> [14,] 4.408676 4.139178
#> [15,] 4.378995 3.981606
#> [16,] 4.389269 4.206622
#> TACGGTACATCCCATC-500.1.1 TACGGTATCTTGTATC-500.1.1
#> [1,] 4.818049 4.416276
#> [2,] 5.233624 4.343677
#> [3,] 4.132460 4.240047
#> [4,] 4.366084 4.319672
#> [5,] 4.251820 4.564988
#> [6,] 4.947598 4.296253
#> [7,] 4.477438 4.263466
#> [8,] 4.831878 4.953747
#> [9,] 4.329694 4.470141
#> [10,] 4.538574 4.254098
#> [11,] 4.574236 4.341335
#> [12,] 4.756914 4.520492
#> [13,] 4.629549 4.409251
#> [14,] 4.276565 4.098361
#> [15,] 4.112809 4.418618
#> [16,] 4.382824 4.455504
#> TACTCATAGCCACCTG-500.1.1 TACTCATCACCAGGTC-500.1.1
#> [1,] 4.251182 4.488406
#> [2,] 4.538150 4.184058
#> [3,] 4.271438 4.339855
#> [4,] 4.652937 4.371014
#> [5,] 4.081026 4.536957
#> [6,] 4.274139 4.455072
#> [7,] 4.223498 4.534783
#> [8,] 4.991897 5.336957
#> [9,] 4.960837 4.682609
#> [10,] 4.661040 4.202174
#> [11,] 4.353815 4.521739
#> [12,] 4.202566 4.589130
#> [13,] 4.536799 4.383333
#> [14,] 4.442944 4.019565
#> [15,] 4.563808 4.128986
#> [16,] 4.235652 4.423913
#> TACTCATTCTACTTAC-500.1.1 TACTCGCTCAAGAAGT-500.1.1
#> [1,] 4.312469 4.433333
#> [2,] 4.149528 4.171958
#> [3,] 4.256334 4.476190
#> [4,] 4.217089 4.237037
#> [5,] 4.733731 4.668783
#> [6,] 4.104819 4.229630
#> [7,] 4.103825 4.265608
#> [8,] 4.995032 5.238095
#> [9,] 4.834078 4.501587
#> [10,] 4.263785 4.388889
#> [11,] 4.128167 4.210582
#> [12,] 4.358669 4.717460
#> [13,] 4.899652 4.469841
#> [14,] 4.144560 4.447619
#> [15,] 3.832091 4.353968
#> [16,] 4.457526 4.152381
#> TAGACCACATGGGACA-500.1.1 TAGACCATCTCGCATC-500.1.1
#> [1,] 4.243427 4.319785
#> [2,] 4.473282 4.377301
#> [3,] 4.089059 4.850460
#> [4,] 4.160305 4.683282
#> [5,] 4.208651 4.596626
#> [6,] 4.192536 4.552914
#> [7,] 4.413910 4.249233
#> [8,] 4.821035 4.937883
#> [9,] 4.707379 4.792945
#> [10,] 4.262935 4.524540
#> [11,] 4.322307 4.330521
#> [12,] 4.374046 4.998466
#> [13,] 4.489398 4.357362
#> [14,] 4.324003 4.317485
#> [15,] 3.985581 4.277607
#> [16,] 4.456319 4.289877
#> TAGAGCTAGTATGACA-500.1.1 TAGAGCTGTCGTCTTC-500.1.1
#> [1,] 4.527240 4.845537
#> [2,] 4.398910 4.305918
#> [3,] 4.134383 4.425276
#> [4,] 4.202179 4.298897
#> [5,] 4.466102 5.012036
#> [6,] 4.277845 4.290873
#> [7,] 4.207022 4.131394
#> [8,] 5.099274 5.100301
#> [9,] 4.481235 5.267803
#> [10,] 4.336562 4.046138
#> [11,] 4.322639 4.171515
#> [12,] 4.619855 4.769308
#> [13,] 4.624697 4.807422
#> [14,] 4.282688 4.434303
#> [15,] 4.109564 3.923771
#> [16,] 4.368039 4.600802
#> TAGCCGGGTGAGTATA-500.1.1 TAGGCATGTATTAGCC-500.1.1
#> [1,] 4.336951 4.281835
#> [2,] 4.384143 4.199438
#> [3,] 4.185465 4.088015
#> [4,] 4.324210 4.455993
#> [5,] 4.310052 4.558989
#> [6,] 4.224634 4.367041
#> [7,] 4.418594 4.060861
#> [8,] 4.703634 5.207865
#> [9,] 4.788108 4.917603
#> [10,] 4.438886 4.588951
#> [11,] 4.332232 4.665730
#> [12,] 4.434167 4.306180
#> [13,] 4.797546 4.536517
#> [14,] 3.907975 5.026217
#> [15,] 4.216612 4.367978
#> [16,] 4.551675 4.415730
#> TAGGCATTCATCTGCC-500.1.1 TAGTGGTGTTTGGCGC-500.1.1
#> [1,] 4.300386 4.324113
#> [2,] 4.349807 4.253191
#> [3,] 4.454054 4.337589
#> [4,] 4.369884 4.608511
#> [5,] 4.502703 4.259574
#> [6,] 4.513514 4.527660
#> [7,] 4.487259 4.143972
#> [8,] 4.605405 5.053191
#> [9,] 4.554440 4.772340
#> [10,] 4.349035 4.424113
#> [11,] 4.250965 4.268085
#> [12,] 4.306564 4.532624
#> [13,] 4.221622 4.593617
#> [14,] 4.227799 4.768085
#> [15,] 4.081081 4.266667
#> [16,] 4.364479 4.252482
#> TAGTGGTTCAGTCAGT-500.1.1 TAGTTGGAGGAGTAGA-500.1.1
#> [1,] 4.395798 4.673469
#> [2,] 4.434412 4.692420
#> [3,] 4.299830 4.405977
#> [4,] 4.509370 4.668367
#> [5,] 4.248154 4.459184
#> [6,] 4.525838 4.418367
#> [7,] 4.282226 4.319971
#> [8,] 4.818853 5.110058
#> [9,] 4.721181 4.770408
#> [10,] 4.624645 4.435131
#> [11,] 4.262919 4.379738
#> [12,] 4.268030 4.378280
#> [13,] 4.691085 4.652332
#> [14,] 4.717206 4.592566
#> [15,] 4.567859 4.408163
#> [16,] 4.350369 4.427843
#> TAGTTGGTCGGTTCGG-500.1.1 TATCAGGAGTGAACAT-500.1.1
#> [1,] 4.553979 4.257119
#> [2,] 4.339659 4.365997
#> [3,] 4.304896 4.308208
#> [4,] 4.410301 4.316583
#> [5,] 4.387817 4.607203
#> [6,] 4.354489 4.261307
#> [7,] 4.271568 4.292295
#> [8,] 5.030458 4.803183
#> [9,] 4.820603 4.276382
#> [10,] 4.335353 4.468174
#> [11,] 4.260883 4.500838
#> [12,] 4.438686 4.782245
#> [13,] 4.475522 4.492462
#> [14,] 4.302344 4.006700
#> [15,] 4.167278 4.448074
#> [16,] 4.484293 4.441374
#> TATCAGGCATCAGTAC-500.1.1 TATCTCAAGTACGCGA-500.1.1
#> [1,] 4.774011 4.276646
#> [2,] 4.411017 4.388715
#> [3,] 4.388418 4.149687
#> [4,] 4.677966 4.264890
#> [5,] 4.545198 4.326019
#> [6,] 4.481638 4.520376
#> [7,] 4.194915 4.315047
#> [8,] 5.272599 4.883229
#> [9,] 4.615819 4.466301
#> [10,] 4.426554 4.721787
#> [11,] 4.362994 4.449060
#> [12,] 4.752825 4.431818
#> [13,] 4.467514 4.209248
#> [14,] 4.673729 4.176332
#> [15,] 4.224576 4.362069
#> [16,] 4.021186 4.277429
#> TATCTCACACGGATAG-500.1.1 TATCTCAGTGATGTCT-500.1.1
#> [1,] 4.604502 4.569910
#> [2,] 4.063955 4.349141
#> [3,] 4.090304 4.220769
#> [4,] 4.332310 4.361406
#> [5,] 4.635457 4.251022
#> [6,] 4.217447 4.289452
#> [7,] 4.377590 4.151267
#> [8,] 4.781530 4.798038
#> [9,] 4.411614 4.476697
#> [10,] 4.129957 4.683565
#> [11,] 4.192888 4.745707
#> [12,] 4.349962 4.236304
#> [13,] 4.443592 4.450531
#> [14,] 4.150934 4.192150
#> [15,] 4.073420 3.971382
#> [16,] 4.354311 4.394930
#> TATTACCGTCTCTTTA-500.1.1 TATTACCGTTATCACG-500.1.1
#> [1,] 4.336643 4.576164
#> [2,] 4.574007 4.480663
#> [3,] 4.326715 4.483031
#> [4,] 4.082130 4.503552
#> [5,] 4.483755 4.470403
#> [6,] 4.389892 4.510655
#> [7,] 4.324910 3.955801
#> [8,] 4.669675 5.414365
#> [9,] 4.565884 4.516180
#> [10,] 4.342960 4.130229
#> [11,] 4.175090 4.257301
#> [12,] 4.532491 4.371744
#> [13,] 4.557762 4.634570
#> [14,] 4.112816 4.277822
#> [15,] 4.169675 4.274665
#> [16,] 4.558664 4.348066
#> TCACGAAAGTGCCAGA-500.1.1 TCACGAACAATAAGCA-500.1.1
#> [1,] 4.247357 4.576951
#> [2,] 4.493658 4.440229
#> [3,] 4.492600 4.589835
#> [4,] 4.467230 4.561203
#> [5,] 4.204017 4.829635
#> [6,] 4.297040 4.445240
#> [7,] 4.554968 4.345741
#> [8,] 4.653277 4.970651
#> [9,] 4.594080 4.666428
#> [10,] 4.326638 4.548318
#> [11,] 4.440803 4.406586
#> [12,] 4.597252 4.690050
#> [13,] 4.338266 4.299213
#> [14,] 4.153277 4.494631
#> [15,] 4.319239 4.324982
#> [16,] 4.441860 4.367215
#> TCACGAAGTAAGTGTA-500.1.1 TCACGAATCCAGAAGG-500.1.1
#> [1,] 4.502805 4.684283
#> [2,] 4.244039 4.394647
#> [3,] 4.319074 4.162663
#> [4,] 4.402525 4.075498
#> [5,] 4.652174 4.680165
#> [6,] 4.267181 4.459163
#> [7,] 3.986676 4.457104
#> [8,] 5.311360 4.908030
#> [9,] 4.747546 4.650652
#> [10,] 4.375175 4.610844
#> [11,] 4.239130 4.269732
#> [12,] 4.597475 4.625944
#> [13,] 4.652875 4.499657
#> [14,] 4.333100 4.155800
#> [15,] 4.279102 4.246397
#> [16,] 4.335203 4.743995
#> TCAGATGAGACTTGAA-500.1.1 TCAGCAACACGAAATA-500.1.1
#> [1,] 4.395139 4.407482
#> [2,] 4.184722 4.145602
#> [3,] 4.098611 4.130435
#> [4,] 4.760417 4.171891
#> [5,] 4.429167 4.533873
#> [6,] 4.247917 4.231547
#> [7,] 4.043750 4.160768
#> [8,] 4.970833 4.765420
#> [9,] 4.840972 4.997978
#> [10,] 4.318056 4.476239
#> [11,] 4.261111 4.284125
#> [12,] 4.430556 4.619818
#> [13,] 4.543750 4.759353
#> [14,] 4.838194 4.178969
#> [15,] 4.350000 4.138524
#> [16,] 4.158333 4.889788
#> TCAGCAATCGCAAGCC-500.1.1 TCAGCTCAGAGTGAGA-500.1.1
#> [1,] 4.263014 4.187359
#> [2,] 4.177169 4.180587
#> [3,] 4.064840 4.471783
#> [4,] 4.732420 4.222348
#> [5,] 4.420091 4.168172
#> [6,] 4.237443 4.113995
#> [7,] 4.161644 4.365688
#> [8,] 4.717808 4.855530
#> [9,] 4.773516 4.793454
#> [10,] 4.375342 4.664786
#> [11,] 4.360731 4.295711
#> [12,] 4.170776 4.897291
#> [13,] 4.648402 4.387133
#> [14,] 5.000913 4.262980
#> [15,] 4.066667 4.465011
#> [16,] 4.182648 4.553047
#> TCAGCTCCACACAGAG-500.1.1 TCAGGATTCTTCCTTC-500.1.1
#> [1,] 4.774167 4.222147
#> [2,] 4.548333 3.838995
#> [3,] 3.931667 4.521060
#> [4,] 4.406667 4.317935
#> [5,] 4.480833 4.821332
#> [6,] 4.495000 4.768342
#> [7,] 4.170833 4.212636
#> [8,] 4.952500 4.427310
#> [9,] 4.336667 4.821332
#> [10,] 4.835833 4.518342
#> [11,] 4.314167 4.635190
#> [12,] 4.292500 4.381793
#> [13,] 4.716667 3.939538
#> [14,] 4.209167 4.635870
#> [15,] 3.825000 4.393342
#> [16,] 4.204167 4.441576
#> TCAGGTACACATCCGG-500.1.1 TCAGGTAGTCATCCCT-500.1.1
#> [1,] 4.666036 4.200184
#> [2,] 3.771523 4.122130
#> [3,] 3.735099 4.352617
#> [4,] 4.336802 4.023875
#> [5,] 4.886471 4.381084
#> [6,] 4.074740 4.898072
#> [7,] 4.710501 4.094582
#> [8,] 4.412961 4.916437
#> [9,] 4.201987 4.519743
#> [10,] 3.777200 4.247016
#> [11,] 3.909650 4.283747
#> [12,] 4.183065 4.325069
#> [13,] 4.316935 4.725436
#> [14,] 4.307474 4.671258
#> [15,] 3.741249 4.081726
#> [16,] 3.913434 5.210285
#> TCCACACCACGGTAGA-500.1.1 TCCCGATCACAACGTT-500.1.1
#> [1,] 4.236635 4.625118
#> [2,] 4.304119 4.066100
#> [3,] 4.334794 4.074599
#> [4,] 4.745837 4.003777
#> [5,] 4.252410 4.516525
#> [6,] 4.656442 4.199245
#> [7,] 4.347940 4.544854
#> [8,] 4.902717 5.038716
#> [9,] 5.048203 4.414542
#> [10,] 4.298861 4.222852
#> [11,] 4.248904 4.175637
#> [12,] 4.347940 4.510859
#> [13,] 4.513585 4.386213
#> [14,] 4.694128 4.171860
#> [15,] 4.224365 4.200189
#> [16,] 4.271691 4.457979
#> TCGCGAGAGAAGGACA-500.1.1 TCGCGAGGTCCGTTAA-500.1.1
#> [1,] 4.367311 4.579496
#> [2,] 4.646749 4.281494
#> [3,] 4.583480 4.165943
#> [4,] 4.489455 4.436142
#> [5,] 4.355009 4.358818
#> [6,] 4.488576 4.552563
#> [7,] 4.094903 4.390096
#> [8,] 4.937610 4.677672
#> [9,] 4.602812 4.674196
#> [10,] 4.558875 4.580365
#> [11,] 4.359402 4.398784
#> [12,] 4.954306 4.292789
#> [13,] 4.496485 4.465682
#> [14,] 4.347100 4.372719
#> [15,] 4.462214 4.058210
#> [16,] 4.270650 4.370113
#> TCGGGACAGACTAGAT-500.1.1 TCGGTAAAGGCATTGG-500.1.1
#> [1,] 4.533183 4.315397
#> [2,] 4.358830 4.394040
#> [3,] 4.265467 4.537252
#> [4,] 4.472441 4.394868
#> [5,] 4.421822 4.329470
#> [6,] 4.236220 4.356788
#> [7,] 4.224972 4.004967
#> [8,] 4.814398 5.106788
#> [9,] 4.588301 5.153974
#> [10,] 4.412823 4.255795
#> [11,] 4.173228 4.181291
#> [12,] 4.473566 4.647351
#> [13,] 4.310461 4.347682
#> [14,] 3.885264 4.658940
#> [15,] 4.220472 3.875828
#> [16,] 4.596175 4.270695
#> TCGGTAAGTCAAGCGA-500.1.1 TCGTACCAGCGCCTTG-500.1.1
#> [1,] 4.239478 4.290179
#> [2,] 4.344991 4.413393
#> [3,] 4.379964 4.232143
#> [4,] 4.319502 4.213393
#> [5,] 4.529342 4.570536
#> [6,] 4.468287 4.300000
#> [7,] 4.432128 4.514286
#> [8,] 4.685240 4.903571
#> [9,] 4.440427 5.064286
#> [10,] 4.397747 4.092857
#> [11,] 4.675756 4.330357
#> [12,] 4.430350 4.564286
#> [13,] 4.268524 4.427679
#> [14,] 4.277416 4.168750
#> [15,] 4.301126 4.195536
#> [16,] 4.401897 4.639286
#> TCGTACCAGGGATGGG-500.1.1 TCGTACCCAGAAGCAC-500.1.1
#> [1,] 4.236322 4.263684
#> [2,] 4.279635 4.164639
#> [3,] 4.610182 4.401825
#> [4,] 4.204407 4.357950
#> [5,] 4.432371 4.531712
#> [6,] 4.423252 4.654214
#> [7,] 3.987842 4.391399
#> [8,] 5.278116 4.588184
#> [9,] 5.141337 4.719809
#> [10,] 4.280395 4.304083
#> [11,] 4.325988 4.539531
#> [12,] 4.203647 4.440921
#> [13,] 4.567629 3.875326
#> [14,] 4.649696 4.462641
#> [15,] 4.120821 4.213293
#> [16,] 4.392097 4.503041
#> TCGTACCCATCCCATC-500.1.1 TCTATTGCAAGTACCT-500.1.1
#> [1,] 4.505081 4.569870
#> [2,] 4.455285 4.740286
#> [3,] 4.041667 3.890934
#> [4,] 4.198171 4.222904
#> [5,] 4.598577 4.578732
#> [6,] 4.497967 4.641445
#> [7,] 4.009146 4.391275
#> [8,] 5.136179 4.879346
#> [9,] 4.768293 4.456033
#> [10,] 4.162602 4.661213
#> [11,] 4.334350 4.297887
#> [12,] 4.317073 4.248807
#> [13,] 4.690041 4.843899
#> [14,] 4.413618 4.311520
#> [15,] 4.081301 3.991138
#> [16,] 4.777439 4.533061
#> TCTCATACATTTGCTT-500.1.1 TCTCATAGTGACGCCT-500.1.1
#> [1,] 4.551158 4.431017
#> [2,] 4.035232 4.051360
#> [3,] 4.335907 4.152064
#> [4,] 4.341216 4.171198
#> [5,] 4.752896 4.208459
#> [6,] 5.172780 4.024169
#> [7,] 4.339768 4.454179
#> [8,] 4.745174 4.540785
#> [9,] 4.619691 4.644512
#> [10,] 4.563224 4.353474
#> [11,] 4.660714 3.923464
#> [12,] 4.503378 5.003021
#> [13,] 3.910232 4.307150
#> [14,] 4.594112 4.007049
#> [15,] 4.269305 4.251762
#> [16,] 4.352799 4.643505
#> TCTCATATCGTTACAG-500.1.1 TCTCTAAGTAGCGATG-500.1.1
#> [1,] 4.401021 4.349345
#> [2,] 4.495746 4.356831
#> [3,] 4.562677 4.434810
#> [4,] 4.330119 4.429819
#> [5,] 4.582530 4.461634
#> [6,] 4.550199 4.198378
#> [7,] 4.102099 4.004991
#> [8,] 4.855360 4.865253
#> [9,] 4.725468 4.767935
#> [10,] 4.247873 4.286962
#> [11,] 4.314237 4.363069
#> [12,] 4.460579 4.333749
#> [13,] 4.326716 4.150343
#> [14,] 4.213840 4.336245
#> [15,] 4.162223 4.414847
#> [16,] 4.757799 4.759201
#> TCTCTAAGTCATATCG-500.1.1 TCTGAGAGTCAGTGGA-500.1.1
#> [1,] 4.358741 4.161943
#> [2,] 4.206297 4.233918
#> [3,] 4.377796 4.536662
#> [4,] 4.304060 4.202429
#> [5,] 4.335543 4.660369
#> [6,] 4.375311 4.955016
#> [7,] 4.191384 4.150247
#> [8,] 5.183099 4.992353
#> [9,] 4.922949 4.573999
#> [10,] 4.468103 4.476833
#> [11,] 4.217896 4.889339
#> [12,] 4.469760 4.322537
#> [13,] 4.853355 4.329285
#> [14,] 4.811930 4.542510
#> [15,] 4.421707 4.246964
#> [16,] 4.187241 4.579397
#> TCTGAGAGTTCAGGCC-500.1.1 TGAAAGACATGCATGT-500.1.1
#> [1,] 4.375716 4.289263
#> [2,] 4.285223 4.225962
#> [3,] 3.871707 4.364583
#> [4,] 3.985109 4.157853
#> [5,] 4.563574 4.381410
#> [6,] 4.011455 4.003205
#> [7,] 4.556701 4.015224
#> [8,] 4.718213 4.768429
#> [9,] 4.907216 4.647436
#> [10,] 4.344788 4.296474
#> [11,] 4.120275 4.390224
#> [12,] 4.764032 4.320513
#> [13,] 4.649485 4.330128
#> [14,] 4.235968 4.044872
#> [15,] 4.668958 4.119391
#> [16,] 4.665521 4.652244
#> TGAAAGATCGAGGTAG-500.1.1 TGACAACAGAACAACT-500.1.1
#> [1,] 4.608423 4.378799
#> [2,] 4.255376 4.180919
#> [3,] 4.358423 4.283392
#> [4,] 4.290323 4.393640
#> [5,] 4.208781 4.638163
#> [6,] 4.404122 4.175265
#> [7,] 4.353943 4.412721
#> [8,] 4.673835 4.634629
#> [9,] 4.338710 4.304594
#> [10,] 4.422043 4.161131
#> [11,] 4.151434 3.957597
#> [12,] 4.483871 4.117314
#> [13,] 4.406810 4.243816
#> [14,] 3.981183 4.319435
#> [15,] 4.409498 4.140636
#> [16,] 4.511649 4.186572
#> TGACAACAGCCCTAAT-500.1.1 TGACGGCCAGGATCGA-500.1.1
#> [1,] 4.468758 4.271118
#> [2,] 4.085421 4.434433
#> [3,] 4.393093 4.200322
#> [4,] 4.188241 4.578439
#> [5,] 4.605326 4.313757
#> [6,] 4.129713 4.575221
#> [7,] 4.262062 4.529364
#> [8,] 4.643027 4.547064
#> [9,] 4.350646 4.768302
#> [10,] 4.190878 4.419147
#> [11,] 4.240707 4.397426
#> [12,] 4.355655 4.250201
#> [13,] 4.665436 4.446500
#> [14,] 4.035065 4.700724
#> [15,] 4.269444 4.337892
#> [16,] 4.408648 4.382140
#> TGACGGCCAGGGTTAG-500.1.1 TGACGGCTCTCGTTTA-500.1.1
#> [1,] 4.704478 4.403493
#> [2,] 5.097015 4.099563
#> [3,] 4.124627 4.404367
#> [4,] 4.416418 4.868122
#> [5,] 4.502239 4.441048
#> [6,] 4.820896 4.698690
#> [7,] 4.588806 4.568559
#> [8,] 4.755224 5.184279
#> [9,] 3.973134 4.382533
#> [10,] 4.838060 4.521397
#> [11,] 4.323881 4.475109
#> [12,] 4.534328 4.732751
#> [13,] 4.518657 4.136245
#> [14,] 4.149254 4.284716
#> [15,] 3.653731 4.174672
#> [16,] 4.181343 4.302183
#> TGACTAGCATGTTGAC-500.1.1 TGACTAGTCTGCGGCA-500.1.1
#> [1,] 4.379974 4.673887
#> [2,] 4.229598 4.244284
#> [3,] 4.345498 4.310469
#> [4,] 4.297268 4.283995
#> [5,] 4.494407 4.742479
#> [6,] 4.671374 4.262335
#> [7,] 4.306804 3.941035
#> [8,] 4.741243 4.926594
#> [9,] 4.625344 4.805054
#> [10,] 4.394462 4.424789
#> [11,] 4.374289 4.234657
#> [12,] 4.499725 4.719615
#> [13,] 4.455712 4.938628
#> [14,] 4.295984 4.103490
#> [15,] 4.128736 4.269555
#> [16,] 4.677425 4.676294
#> TGACTTTAGGTGTGGT-500.1.1 TGACTTTAGTGAACAT-500.1.1
#> [1,] 4.293976 4.471285
#> [2,] 4.042169 4.391978
#> [3,] 3.844578 4.311759
#> [4,] 4.478313 4.519599
#> [5,] 4.727711 4.413856
#> [6,] 4.339759 4.453054
#> [7,] 3.922892 4.347311
#> [8,] 5.000000 4.977211
#> [9,] 4.742169 4.320875
#> [10,] 4.437349 4.451231
#> [11,] 4.114458 4.254330
#> [12,] 4.440964 4.573382
#> [13,] 4.630120 4.395624
#> [14,] 4.042169 4.379216
#> [15,] 4.030120 4.602552
#> [16,] 4.854217 4.668186
#> TGAGCATCATGCCTTC-500.1.1 TGAGCCGAGGGCATGT-500.1.1
#> [1,] 4.643556 4.636964
#> [2,] 3.760196 4.028603
#> [3,] 3.683524 4.528053
#> [4,] 4.706362 4.176018
#> [5,] 4.863377 4.570957
#> [6,] 3.964111 4.712871
#> [7,] 4.431485 4.343234
#> [8,] 4.433931 4.902090
#> [9,] 4.154568 4.831683
#> [10,] 3.860930 3.943894
#> [11,] 3.746737 4.254125
#> [12,] 3.971452 4.354235
#> [13,] 4.430261 4.731573
#> [14,] 4.075856 4.346535
#> [15,] 3.908238 4.236524
#> [16,] 4.008972 4.485149
#> TGATTTCAGGACAGAA-500.1.1 TGATTTCGTGGTACAG-500.1.1
#> [1,] 4.375688 4.534857
#> [2,] 4.319032 4.311429
#> [3,] 4.605061 4.337714
#> [4,] 4.312981 4.420571
#> [5,] 4.520352 4.715429
#> [6,] 4.342684 4.795429
#> [7,] 4.095160 4.401143
#> [8,] 4.805831 4.958286
#> [9,] 4.876788 4.710286
#> [10,] 4.320682 4.525714
#> [11,] 4.260176 4.464000
#> [12,] 4.412541 4.764571
#> [13,] 4.512101 4.224000
#> [14,] 4.544554 4.442857
#> [15,] 4.329483 4.231429
#> [16,] 4.936194 4.268000
#> TGCACCTTCATGCAAC-500.1.1 TGCACCTTCTGAGTGT-500.1.1
#> [1,] 4.567732 4.590984
#> [2,] 4.356164 4.073770
#> [3,] 4.069254 4.209836
#> [4,] 4.367580 4.181967
#> [5,] 4.442161 4.675410
#> [6,] 4.307458 4.455738
#> [7,] 4.407154 4.013934
#> [8,] 4.838661 5.121311
#> [9,] 4.987823 4.645082
#> [10,] 4.270167 4.282787
#> [11,] 4.429224 4.316393
#> [12,] 4.241248 4.431967
#> [13,] 4.637747 4.657377
#> [14,] 4.566210 4.257377
#> [15,] 4.105023 4.086066
#> [16,] 4.429985 4.280328
#> TGCCAAACAAGTAATG-500.1.1 TGCCCATCACCGCTAG-500.1.1
#> [1,] 4.593455 4.521824
#> [2,] 4.170182 3.654156
#> [3,] 4.615273 3.951348
#> [4,] 4.332364 4.184598
#> [5,] 3.953455 5.167362
#> [6,] 4.148364 3.725327
#> [7,] 4.010182 4.927996
#> [8,] 5.057455 4.025299
#> [9,] 5.232727 4.224632
#> [10,] 4.264727 3.680845
#> [11,] 3.962182 3.852933
#> [12,] 4.465455 4.107034
#> [13,] 4.460364 4.320545
#> [14,] 4.625455 4.634974
#> [15,] 4.051636 3.884626
#> [16,] 4.437091 3.808451
#> TGCCCTAGTGTGCGTC-500.1.1 TGCCCTATCACTTATC-500.1.1
#> [1,] 4.628467 4.295515
#> [2,] 3.916788 4.389622
#> [3,] 4.278102 4.360598
#> [4,] 4.443066 4.408971
#> [5,] 4.854745 4.141601
#> [6,] 3.943796 4.276165
#> [7,] 4.410219 4.343008
#> [8,] 4.378832 4.621812
#> [9,] 4.194891 4.557608
#> [10,] 4.047445 4.408971
#> [11,] 4.081752 4.154793
#> [12,] 4.538686 4.368514
#> [13,] 4.024818 4.467898
#> [14,] 3.784672 4.124011
#> [15,] 4.587591 4.279683
#> [16,] 4.391241 4.567282
#> TGCGCAGTCAGCTTAG-500.1.1 TGCGGGTGTGGTGTAG-500.1.1
#> [1,] 4.565183 4.522350
#> [2,] 4.321145 4.014049
#> [3,] 4.219396 4.116220
#> [4,] 4.273450 4.174968
#> [5,] 4.563593 4.786718
#> [6,] 4.190779 4.274585
#> [7,] 4.107313 3.998723
#> [8,] 4.629571 5.075351
#> [9,] 4.440382 4.814815
#> [10,] 4.480127 4.293742
#> [11,] 4.631161 4.477650
#> [12,] 4.387917 4.383142
#> [13,] 4.682830 4.742018
#> [14,] 4.115262 4.794381
#> [15,] 4.100159 4.233716
#> [16,] 4.317965 4.569604
#> TGCGTGGAGTGTTTGC-500.1.1 TGCGTGGTCCCAACGG-500.1.1
#> [1,] 4.288764 4.268187
#> [2,] 4.358427 4.182491
#> [3,] 4.195506 4.770654
#> [4,] 4.060674 4.235512
#> [5,] 4.526966 4.553637
#> [6,] 4.312360 4.654747
#> [7,] 4.184270 4.277435
#> [8,] 4.878652 4.895808
#> [9,] 4.775281 4.630086
#> [10,] 4.342697 4.478422
#> [11,] 4.121348 4.699137
#> [12,] 4.270787 4.454377
#> [13,] 4.615730 4.158446
#> [14,] 4.171910 4.369914
#> [15,] 4.221348 4.219482
#> [16,] 4.496629 4.591862
#> TGCTACCAGTGTGGCA-500.1.1 TGCTACCGTGTGCCTG-500.1.1
#> [1,] 4.817916 4.314050
#> [2,] 4.034080 4.059917
#> [3,] 4.263875 4.058884
#> [4,] 4.257059 4.221074
#> [5,] 4.664070 4.614669
#> [6,] 4.324245 4.026860
#> [7,] 4.205453 4.173554
#> [8,] 4.830574 4.962810
#> [9,] 4.850049 4.807851
#> [10,] 4.437196 4.252066
#> [11,] 4.231743 4.144628
#> [12,] 4.603700 4.433884
#> [13,] 4.745862 5.254132
#> [14,] 4.412853 4.159091
#> [15,] 4.312561 4.122934
#> [16,] 4.666018 4.425620
#> TGCTACCTCTATCCCG-500.1.1 TGCTACCTCTGGTATG-500.1.1
#> [1,] 4.458293 4.354749
#> [2,] 4.220518 4.445251
#> [3,] 4.010547 4.536313
#> [4,] 4.263663 4.164804
#> [5,] 4.825503 4.504469
#> [6,] 4.472675 4.374302
#> [7,] 4.291467 4.337989
#> [8,] 4.846596 4.629050
#> [9,] 4.374880 4.518994
#> [10,] 4.190796 4.320670
#> [11,] 4.476510 4.536872
#> [12,] 4.447747 4.388827
#> [13,] 4.651007 4.337430
#> [14,] 4.629914 4.344134
#> [15,] 4.118888 4.180447
#> [16,] 4.377756 4.587709
#> TGCTGCTGTAGGAGTC-500.1.1 TGCTGCTGTCTCCATC-500.1.1
#> [1,] 4.258032 4.485083
#> [2,] 4.328404 4.393370
#> [3,] 4.382968 4.444751
#> [4,] 4.430903 4.680110
#> [5,] 4.339113 4.390608
#> [6,] 4.455380 4.598895
#> [7,] 4.061703 4.612707
#> [8,] 4.902091 4.710497
#> [9,] 4.866905 4.619337
#> [10,] 4.164202 4.569061
#> [11,] 4.524222 4.315470
#> [12,] 4.548700 4.714365
#> [13,] 4.423253 4.467956
#> [14,] 4.227435 4.395028
#> [15,] 4.032126 4.514365
#> [16,] 4.672106 4.377348
#> TGCTGCTTCTGTCCGT-500.1.1 TGGACGCCAGTATGCT-500.1.1
#> [1,] 4.162289 4.386364
#> [2,] 4.228893 4.134298
#> [3,] 4.100375 4.194215
#> [4,] 4.469981 4.382645
#> [5,] 4.614447 4.440909
#> [6,] 4.501876 4.383058
#> [7,] 4.121013 4.168182
#> [8,] 4.881801 4.921488
#> [9,] 4.613508 5.004545
#> [10,] 4.363039 4.388017
#> [11,] 4.097561 4.426446
#> [12,] 4.450281 4.417769
#> [13,] 4.580675 4.573967
#> [14,] 4.389306 4.887190
#> [15,] 4.237336 4.282645
#> [16,] 5.050657 4.360744
#> TGGCGCAAGAAGGTGA-500.1.1 TGGGAAGAGACTCGGA-500.1.1
#> [1,] 4.142222 4.390135
#> [2,] 4.403175 4.419283
#> [3,] 4.391746 4.558296
#> [4,] 4.567619 4.553064
#> [5,] 4.495873 4.428999
#> [6,] 4.220952 4.613602
#> [7,] 4.195556 4.312407
#> [8,] 4.770794 4.857250
#> [9,] 4.718095 4.871450
#> [10,] 4.481270 4.511958
#> [11,] 4.295238 4.555306
#> [12,] 4.367619 4.598655
#> [13,] 4.417143 4.398356
#> [14,] 4.113651 4.469357
#> [15,] 4.205714 4.402093
#> [16,] 4.652698 4.492526
#> TGGGAAGGTCTAGTGT-500.1.1 TGGGCGTGTGATAAAC-500.1.1
#> [1,] 4.785877 4.374737
#> [2,] 4.405467 4.574737
#> [3,] 4.371298 4.456842
#> [4,] 4.142369 4.557895
#> [5,] 4.609339 4.328421
#> [6,] 4.383827 4.222105
#> [7,] 3.997722 4.405263
#> [8,] 5.291572 5.054737
#> [9,] 4.619590 4.452632
#> [10,] 4.437358 4.461053
#> [11,] 4.192483 4.355789
#> [12,] 4.263098 5.012632
#> [13,] 5.007973 4.492632
#> [14,] 4.120729 4.251579
#> [15,] 3.733485 4.635789
#> [16,] 4.240319 4.468421
#> TGGGCGTGTGTCAATC-500.1.1 TGGTTAGAGAGAACAG-500.1.1
#> [1,] 4.867387 4.559730
#> [2,] 4.327112 4.308790
#> [3,] 4.189587 4.069121
#> [4,] 4.611984 4.277235
#> [5,] 4.403733 4.574756
#> [6,] 4.338900 4.583020
#> [7,] 3.776031 4.495116
#> [8,] 4.878193 4.932382
#> [9,] 4.548134 4.685950
#> [10,] 4.369352 4.371901
#> [11,] 4.373281 4.189331
#> [12,] 4.256385 4.514651
#> [13,] 4.762279 4.730278
#> [14,] 4.275049 4.367393
#> [15,] 3.957760 4.027047
#> [16,] 4.068762 4.691961
#> TGGTTAGAGGCATGTG-500.1.1 TGGTTCCCACATTAGC-500.1.1
#> [1,] 4.470435 4.523952
#> [2,] 4.340870 4.187625
#> [3,] 4.347826 4.082834
#> [4,] 4.507826 4.012974
#> [5,] 4.302609 4.380240
#> [6,] 4.460000 4.327345
#> [7,] 4.241739 4.011976
#> [8,] 5.064348 4.864271
#> [9,] 4.554783 4.439122
#> [10,] 4.508696 4.546906
#> [11,] 4.133913 4.261477
#> [12,] 4.491304 4.644711
#> [13,] 4.650435 4.434132
#> [14,] 4.474783 4.468064
#> [15,] 4.104348 4.318363
#> [16,] 4.329565 4.851297
#> TGGTTCCCACTAAGTC-500.1.1 TGGTTCCGTATCTGCA-500.1.1
#> [1,] 4.407825 4.304348
#> [2,] 4.346154 4.183136
#> [3,] 4.301724 4.305665
#> [4,] 4.339523 4.428195
#> [5,] 4.552387 4.555995
#> [6,] 4.572281 4.359684
#> [7,] 4.287798 4.295125
#> [8,] 4.809682 5.019763
#> [9,] 4.606764 4.902503
#> [10,] 4.376658 4.816864
#> [11,] 4.236737 4.271410
#> [12,] 4.445623 4.665349
#> [13,] 4.318302 4.964427
#> [14,] 4.090186 4.338603
#> [15,] 4.153846 4.071146
#> [16,] 4.763263 4.490119
#> TGTATTCTCGGATGTT-500.1.1 TGTCCCAGTTCGGGCT-500.1.1
#> [1,] 5.001239 4.661494
#> [2,] 4.322181 4.250242
#> [3,] 4.350682 4.206596
#> [4,] 4.299876 4.533463
#> [5,] 4.736059 4.718720
#> [6,] 4.320942 4.739088
#> [7,] 3.945477 4.356935
#> [8,] 4.951673 4.946654
#> [9,] 5.272615 4.450048
#> [10,] 4.030979 4.487876
#> [11,] 4.353160 4.405432
#> [12,] 4.318463 4.751697
#> [13,] 5.168525 4.932105
#> [14,] 4.136307 4.287100
#> [15,] 3.925651 4.422890
#> [16,] 4.697646 4.580989
#> TGTGGTACACCCATGG-500.1.1 TGTGGTACAGTAAGCG-500.1.1
#> [1,] 4.103774 4.427954
#> [2,] 4.662399 4.474063
#> [3,] 4.294474 4.501441
#> [4,] 4.441375 4.378002
#> [5,] 4.113881 4.472142
#> [6,] 4.601752 4.330932
#> [7,] 4.185310 4.063881
#> [8,] 4.907008 5.125360
#> [9,] 5.160377 4.938040
#> [10,] 4.969003 4.273295
#> [11,] 4.133423 4.404899
#> [12,] 4.316038 4.365994
#> [13,] 4.403639 4.314121
#> [14,] 4.670485 4.350144
#> [15,] 4.740566 4.146974
#> [16,] 4.369946 4.565802
#> TGTGGTAGTTCTCATT-500.1.1 TGTGGTATCAGTCAGT-500.1.1
#> [1,] 4.527453 4.326954
#> [2,] 4.065421 3.883573
#> [3,] 4.292640 4.429825
#> [4,] 4.669977 4.012759
#> [5,] 4.395444 4.906699
#> [6,] 4.441589 4.759171
#> [7,] 4.398949 4.346093
#> [8,] 4.966706 4.787081
#> [9,] 4.622079 4.795853
#> [10,] 4.377921 4.566188
#> [11,] 4.447430 4.899522
#> [12,] 4.367407 4.254386
#> [13,] 4.503505 3.921850
#> [14,] 4.387266 4.623604
#> [15,] 4.375000 4.263158
#> [16,] 4.324766 4.881978
#> TGTGTTTGTTGAGGTG-500.1.1 TGTTCCGCAATCTACG-500.1.1
#> [1,] 3.791910 4.436735
#> [2,] 4.195163 4.351701
#> [3,] 4.857381 4.271429
#> [4,] 4.674312 4.513605
#> [5,] 3.876981 4.723810
#> [6,] 4.203086 4.253741
#> [7,] 4.192661 4.030612
#> [8,] 4.887406 4.861905
#> [9,] 4.281902 5.071429
#> [10,] 5.422852 4.503401
#> [11,] 5.120100 4.306803
#> [12,] 4.031276 4.511565
#> [13,] 3.939950 4.882993
#> [14,] 4.717264 4.246939
#> [15,] 4.843620 3.951701
#> [16,] 4.737281 4.536735
#> TTAACTCTCTCTAAGG-500.1.1 TTAACTCTCTTAGCCC-500.1.1
#> [1,] 4.315392 4.507442
#> [2,] 4.588291 4.319631
#> [3,] 4.160529 4.225372
#> [4,] 4.375826 4.372785
#> [5,] 4.557129 4.512403
#> [6,] 4.546742 4.510276
#> [7,] 4.400378 4.597449
#> [8,] 4.766761 4.853296
#> [9,] 4.744098 4.834869
#> [10,] 4.401322 4.542877
#> [11,] 4.258735 4.176471
#> [12,] 4.711992 4.546421
#> [13,] 4.318225 4.778172
#> [14,] 4.220963 4.637845
#> [15,] 4.233239 4.178597
#> [16,] 4.687441 4.525868
#> TTAGGACTCAGAGGTG-500.1.1 TTATGCTAGCTACCGC-500.1.1
#> [1,] 4.495079 4.267377
#> [2,] 4.567913 4.419843
#> [3,] 4.191929 4.465807
#> [4,] 4.232283 4.334641
#> [5,] 4.792323 4.289798
#> [6,] 4.442913 4.298206
#> [7,] 4.355315 4.141256
#> [8,] 4.993110 4.955717
#> [9,] 4.609252 5.038677
#> [10,] 4.359252 4.631726
#> [11,] 4.135827 4.232063
#> [12,] 4.275591 4.389013
#> [13,] 4.815945 4.367152
#> [14,] 4.045276 4.494395
#> [15,] 4.407480 4.675448
#> [16,] 4.563976 4.367152
#> TTATGCTGTCACTGGC-500.1.1 TTCGAAGCACACCGAC-500.1.1
#> [1,] 4.603110 4.647334
#> [2,] 4.833061 4.270346
#> [3,] 3.871522 4.555659
#> [4,] 4.459083 4.442470
#> [5,] 4.619476 4.636109
#> [6,] 4.534370 4.338634
#> [7,] 4.366612 3.928906
#> [8,] 5.231588 5.260056
#> [9,] 4.334697 4.592142
#> [10,] 4.675123 4.171188
#> [11,] 4.401800 4.423761
#> [12,] 4.306056 4.341441
#> [13,] 4.655483 4.762395
#> [14,] 4.289689 4.185220
#> [15,] 3.640753 3.781104
#> [16,] 4.342062 4.144060
#> TTCGAAGCATTGGCGC-500.1.1 TTCGAAGGTATTACCG-500.1.1
#> [1,] 4.248160 4.728749
#> [2,] 4.357518 4.359121
#> [3,] 4.347003 4.131805
#> [4,] 4.613039 4.390640
#> [5,] 4.262881 4.622732
#> [6,] 4.426919 4.113658
#> [7,] 4.232387 4.139446
#> [8,] 4.895899 4.732569
#> [9,] 4.507886 5.099331
#> [10,] 4.540484 4.230181
#> [11,] 4.314406 4.114613
#> [12,] 4.355415 4.361987
#> [13,] 4.041009 4.815664
#> [14,] 4.125131 4.025788
#> [15,] 4.156677 4.165234
#> [16,] 4.289169 4.675263
#> TTCGAAGGTTACCAGT-500.1.1 TTCGGTCTCTCTGCTG-500.1.1
#> [1,] 4.346425 4.427854
#> [2,] 4.292044 4.067754
#> [3,] 4.355488 4.770807
#> [4,] 4.051360 4.241740
#> [5,] 4.389728 4.707235
#> [6,] 4.083585 4.955249
#> [7,] 4.442095 4.000418
#> [8,] 4.678751 4.739440
#> [9,] 4.896274 4.740276
#> [10,] 4.733132 4.649519
#> [11,] 4.395770 4.715182
#> [12,] 4.580060 4.595567
#> [13,] 4.725076 3.864910
#> [14,] 4.265861 4.543706
#> [15,] 4.509567 4.560017
#> [16,] 4.671702 4.570054
#> TTCTACACATAAAGGT-500.1.1 TTCTCAAAGTCATGCT-500.1.1
#> [1,] 4.329795 4.635948
#> [2,] 4.368011 4.415080
#> [3,] 4.408351 3.990861
#> [4,] 4.271054 4.246002
#> [5,] 4.329795 4.553694
#> [6,] 4.242746 4.622239
#> [7,] 4.124558 4.258187
#> [8,] 4.995046 5.076923
#> [9,] 4.897381 4.519421
#> [10,] 4.319887 4.715156
#> [11,] 4.282378 4.322925
#> [12,] 4.430998 4.303884
#> [13,] 4.673744 4.721249
#> [14,] 4.518754 4.127951
#> [15,] 4.242746 3.815689
#> [16,] 4.515924 4.121858
#> TTCTCAACATGTTGAC-500.1.1 TTCTTAGCACAAGCCC-500.1.1
#> [1,] 4.306778 4.613973
#> [2,] 4.134364 4.152435
#> [3,] 4.554697 4.329570
#> [4,] 4.304400 4.625265
#> [5,] 4.531510 4.448836
#> [6,] 4.207491 4.566690
#> [7,] 4.241379 4.140438
#> [8,] 4.793103 5.078335
#> [9,] 4.291914 4.796754
#> [10,] 4.268133 4.318984
#> [11,] 4.133175 4.378264
#> [12,] 4.478002 4.369795
#> [13,] 4.167658 4.506704
#> [14,] 4.235434 4.784757
#> [15,] 4.412604 4.350035
#> [16,] 4.517241 4.331687
#> TTCTTAGGTCAAACTC-500.1.1 TTCTTAGTCTCACATT-500.1.1
#> [1,] 4.511485 4.455672
#> [2,] 4.532159 4.029036
#> [3,] 4.308576 4.537360
#> [4,] 4.204441 4.424700
#> [5,] 4.656968 4.711189
#> [6,] 4.413476 4.882307
#> [7,] 4.578101 4.328688
#> [8,] 4.796325 4.952768
#> [9,] 4.750383 4.674797
#> [10,] 4.540582 4.481611
#> [11,] 4.316233 4.692605
#> [12,] 4.519142 4.375919
#> [13,] 4.365237 4.185830
#> [14,] 4.082695 4.655052
#> [15,] 4.055896 4.365854
#> [16,] 4.689893 4.307007
#> TTGAACGCACACGCTG-500.1.1 TTGCCGTCATCCAACA-500.1.1
#> [1,] 4.478180 4.889694
#> [2,] 4.454968 4.106280
#> [3,] 4.127205 4.292271
#> [4,] 4.455896 4.371176
#> [5,] 4.564531 4.558776
#> [6,] 4.302693 4.706119
#> [7,] 4.320334 4.270531
#> [8,] 4.847725 5.074879
#> [9,] 4.908078 4.876812
#> [10,] 4.185701 4.301127
#> [11,] 4.306407 4.384863
#> [12,] 4.248839 4.652174
#> [13,] 4.454039 4.837359
#> [14,] 4.078923 4.274557
#> [15,] 4.182916 3.992754
#> [16,] 4.311049 4.394525
#> TTGCGTCCAAAGTCAA-500.1.1 TTGCGTCGTCACACGC-500.1.1
#> [1,] 3.959739 4.278207
#> [2,] 4.258977 4.477589
#> [3,] 4.211099 4.428903
#> [4,] 4.080522 4.136785
#> [5,] 4.670294 4.192427
#> [6,] 4.208923 4.213292
#> [7,] 4.232862 4.314529
#> [8,] 4.334059 4.751159
#> [9,] 4.648531 4.459042
#> [10,] 4.212187 4.418856
#> [11,] 4.101197 4.105873
#> [12,] 4.706202 4.046368
#> [13,] 4.808487 4.301391
#> [14,] 4.077258 4.197063
#> [15,] 4.133841 4.501546
#> [16,] 4.730141 4.217156
#> TTTGCGCGTACCATCA-500.1.1 TTTGCGCTCTCTGCTG-500.1.1
#> [1,] 4.390988 4.739486
#> [2,] 4.384448 4.255841
#> [3,] 4.214390 4.336449
#> [4,] 4.372820 4.335280
#> [5,] 4.553779 4.503505
#> [6,] 4.488372 4.434579
#> [7,] 4.148983 4.278037
#> [8,] 4.946948 4.974299
#> [9,] 4.805233 4.846963
#> [10,] 4.160610 4.565421
#> [11,] 4.375000 4.269860
#> [12,] 4.445494 4.571262
#> [13,] 4.613372 4.688084
#> [14,] 4.340116 4.612150
#> [15,] 4.273983 4.265187
#> [16,] 4.524709 4.301402
#> TTTGGTTCAATGGATA-500.1.1 TTTGTCAAGCCAGGAT-500.1.1
#> [1,] 4.662162 4.5416
#> [2,] 4.450772 4.3616
#> [3,] 4.216216 4.3184
#> [4,] 4.558880 4.3568
#> [5,] 4.436293 4.5392
#> [6,] 4.267375 4.3360
#> [7,] 4.053089 4.1304
#> [8,] 4.740347 4.9568
#> [9,] 5.095560 4.8304
#> [10,] 4.361969 4.3072
#> [11,] 4.241313 4.5416
#> [12,] 4.483591 4.6136
#> [13,] 4.819498 4.9024
#> [14,] 4.500965 4.1520
#> [15,] 3.964286 3.8208
#> [16,] 4.807915 4.6904
#> TTTGTCAAGGTGGGTT-500.1.1 AAACCTGGTACCATCA-500.1.2
#> [1,] 4.192349 4.599237
#> [2,] 4.318810 4.581425
#> [3,] 4.378852 4.596692
#> [4,] 4.354410 4.325700
#> [5,] 4.668438 4.746819
#> [6,] 4.606801 4.454198
#> [7,] 4.225824 3.689567
#> [8,] 4.919766 5.203562
#> [9,] 4.551541 4.749364
#> [10,] 4.411796 4.165394
#> [11,] 4.691286 4.301527
#> [12,] 4.415515 4.170483
#> [13,] 4.301807 4.432570
#> [14,] 4.380978 4.421120
#> [15,] 4.319872 3.924936
#> [16,] 4.539851 4.347328
#> AAACCTGGTAGCCTCG-500.1.2 AAACCTGGTTCGTGAT-500.1.2
#> [1,] 4.657277 4.392973
#> [2,] 4.582160 4.462703
#> [3,] 4.182316 4.622703
#> [4,] 4.279343 4.369730
#> [5,] 4.841158 4.334054
#> [6,] 4.564163 4.363784
#> [7,] 4.267606 4.109189
#> [8,] 4.899844 4.935135
#> [9,] 4.757433 4.847027
#> [10,] 4.219875 4.249189
#> [11,] 4.242567 4.388108
#> [12,] 4.656495 4.559459
#> [13,] 4.953834 4.283243
#> [14,] 4.220657 4.266486
#> [15,] 4.015649 4.106486
#> [16,] 4.408451 4.563784
#> AAAGATGCATACTACG-500.1.2 AAAGATGGTATTCTCT-500.1.2
#> [1,] 4.373874 4.493934
#> [2,] 4.100000 4.585211
#> [3,] 4.329730 4.269209
#> [4,] 4.410811 4.549971
#> [5,] 4.483784 4.506644
#> [6,] 4.493694 4.385904
#> [7,] 4.328829 4.596765
#> [8,] 4.841441 4.727325
#> [9,] 4.655856 4.696707
#> [10,] 4.218018 4.566724
#> [11,] 4.218018 4.395725
#> [12,] 4.317117 4.525708
#> [13,] 4.948649 4.369728
#> [14,] 4.580180 4.348931
#> [15,] 4.365766 4.353553
#> [16,] 4.736937 4.450607
#> AAAGCAATCCCTAACC-500.1.2 AAAGTAGAGTAATCCC-500.1.2
#> [1,] 4.622699 4.196680
#> [2,] 4.555215 4.356017
#> [3,] 3.923313 3.978423
#> [4,] 4.346626 4.610788
#> [5,] 4.924335 4.254772
#> [6,] 4.185072 4.282158
#> [7,] 4.315951 4.117842
#> [8,] 4.898773 5.077178
#> [9,] 5.295501 5.022407
#> [10,] 4.139059 4.159336
#> [11,] 4.153374 4.402490
#> [12,] 4.748466 4.326971
#> [13,] 4.685072 4.445643
#> [14,] 4.446830 5.138589
#> [15,] 4.275051 4.241494
#> [16,] 4.771984 4.126971
#> AACGTTGAGATCCCGC-500.1.2 AACGTTGTCAGCGATT-500.1.2
#> [1,] 4.361639 4.638740
#> [2,] 4.160894 4.957105
#> [3,] 4.218994 4.232574
#> [4,] 4.389572 4.430295
#> [5,] 4.245810 4.291555
#> [6,] 4.397393 4.850536
#> [7,] 4.115829 4.404826
#> [8,] 4.838361 4.908847
#> [9,] 4.909497 4.098525
#> [10,] 4.169832 4.687668
#> [11,] 4.131099 4.210456
#> [12,] 4.407821 4.656166
#> [13,] 4.348603 4.538204
#> [14,] 4.827188 4.365282
#> [15,] 4.103538 3.931635
#> [16,] 4.636872 4.268767
#> AACGTTGTCGTCCGTT-500.1.2 AACTCAGAGTGTACGG-500.1.2
#> [1,] 4.738189 4.672852
#> [2,] 4.591535 4.461914
#> [3,] 4.297244 4.467773
#> [4,] 4.734252 4.366211
#> [5,] 4.502953 4.596680
#> [6,] 4.572835 4.096680
#> [7,] 4.508858 4.352539
#> [8,] 5.155512 4.661133
#> [9,] 4.549213 4.499023
#> [10,] 4.408465 4.276367
#> [11,] 4.487205 4.394531
#> [12,] 4.455709 4.500977
#> [13,] 4.216535 4.364258
#> [14,] 4.311024 4.126953
#> [15,] 4.387795 4.025391
#> [16,] 4.410433 4.390625
#> AACTCCCTCATTGCGA-500.1.2 AACTGGTGTTTGTTTC-500.1.2
#> [1,] 4.381471 4.600674
#> [2,] 4.281335 4.203875
#> [3,] 4.388965 4.630160
#> [4,] 4.006131 4.573715
#> [5,] 4.455722 4.795282
#> [6,] 4.162807 4.292334
#> [7,] 4.339237 4.438922
#> [8,] 4.625341 5.117102
#> [9,] 4.518392 4.683235
#> [10,] 4.355586 4.482730
#> [11,] 4.300409 4.360573
#> [12,] 4.829700 4.639427
#> [13,] 4.422343 4.424600
#> [14,] 4.064714 4.235046
#> [15,] 4.655995 4.211457
#> [16,] 4.479564 4.276327
#> AAGCCGCTCCTTTCGG-500.1.2 AAGGCAGGTATAATGG-500.1.2
#> [1,] 4.279582 4.440171
#> [2,] 4.055036 4.226496
#> [3,] 4.127133 4.102564
#> [4,] 4.468354 4.179487
#> [5,] 4.626307 4.458120
#> [6,] 4.707760 4.609402
#> [7,] 4.183269 4.228205
#> [8,] 4.960374 4.760684
#> [9,] 4.659329 4.676923
#> [10,] 4.578426 4.369231
#> [11,] 4.673088 4.011111
#> [12,] 4.399560 4.626496
#> [13,] 4.162356 4.747009
#> [14,] 4.239956 4.041026
#> [15,] 4.532196 4.308547
#> [16,] 4.417722 4.364957
#> ACATCAGCACCATGTA-500.1.2 ACATCAGCAGAAGCAC-500.1.2
#> [1,] 4.415617 4.500000
#> [2,] 4.152813 3.984183
#> [3,] 4.180521 4.281195
#> [4,] 4.254408 4.158172
#> [5,] 4.458438 4.359402
#> [6,] 4.304786 5.046573
#> [7,] 4.062972 3.990334
#> [8,] 4.938707 4.940246
#> [9,] 4.929471 4.524605
#> [10,] 4.151134 4.131810
#> [11,] 4.230898 4.007030
#> [12,] 4.476910 4.413005
#> [13,] 4.302267 4.697715
#> [14,] 4.494542 4.584359
#> [15,] 4.020151 4.173111
#> [16,] 4.340890 4.993849
#> ACATGGTAGAGTGACC-500.1.2 ACATGGTTCTCGTTTA-500.1.2
#> [1,] 4.159636 4.334778
#> [2,] 4.056088 4.438787
#> [3,] 4.389262 4.508126
#> [4,] 4.826462 4.889491
#> [5,] 4.229147 4.422535
#> [6,] 4.382071 4.252438
#> [7,] 3.896932 4.374865
#> [8,] 4.810642 4.957746
#> [9,] 5.580537 4.856988
#> [10,] 4.794343 4.239437
#> [11,] 4.569511 4.170098
#> [12,] 4.315916 4.629469
#> [13,] 3.816395 4.419285
#> [14,] 4.106903 5.049837
#> [15,] 4.060403 4.295775
#> [16,] 4.419463 4.494041
#> ACCAGTAGTCAAACTC-500.1.2 ACCAGTATCTGTTTGT-500.1.2
#> [1,] 4.426246 4.649751
#> [2,] 4.052294 4.256716
#> [3,] 4.406019 4.251741
#> [4,] 4.447953 3.917413
#> [5,] 4.544647 4.584080
#> [6,] 4.918599 4.179104
#> [7,] 4.096695 4.379104
#> [8,] 4.737543 4.995025
#> [9,] 4.707943 4.301493
#> [10,] 4.606808 3.971144
#> [11,] 4.658115 4.020896
#> [12,] 4.418846 4.616915
#> [13,] 4.131722 4.777114
#> [14,] 4.814011 4.094527
#> [15,] 4.383818 4.205970
#> [16,] 4.231376 4.650746
#> ACCCACTAGTCGATAA-500.1.2 ACGATACGTGGTAACG-500.1.2
#> [1,] 4.388437 4.742331
#> [2,] 4.471545 4.237376
#> [3,] 4.125565 4.315243
#> [4,] 4.197832 4.554979
#> [5,] 4.542909 4.504011
#> [6,] 4.292683 4.426144
#> [7,] 4.428184 4.212364
#> [8,] 4.625113 5.082114
#> [9,] 4.656730 4.741859
#> [10,] 4.267389 4.455403
#> [11,] 4.336947 4.180746
#> [12,] 4.546522 4.361963
#> [13,] 4.445348 4.789051
#> [14,] 4.561879 4.431336
#> [15,] 4.034327 4.292591
#> [16,] 4.922313 4.560170
#> ACGCCAGCAACACCTA-500.1.2 ACTATCTTCACTGGGC-500.1.2
#> [1,] 4.474419 4.082824
#> [2,] 4.235880 4.419552
#> [3,] 4.123588 4.420231
#> [4,] 4.209967 4.031229
#> [5,] 4.350831 4.298031
#> [6,] 4.289701 4.392396
#> [7,] 4.287708 4.179226
#> [8,] 4.962791 4.825526
#> [9,] 4.629236 4.924644
#> [10,] 4.312292 4.117447
#> [11,] 4.352159 4.345553
#> [12,] 4.217940 4.561439
#> [13,] 4.819934 4.499661
#> [14,] 4.273090 4.401222
#> [15,] 3.926246 4.131025
#> [16,] 4.548837 4.537678
#> ACTGAACCAAGTTAAG-500.1.2 ACTGTCCTCAGAGGTG-500.1.2
#> [1,] 4.191841 4.385480
#> [2,] 4.300441 4.280035
#> [3,] 4.393054 4.389801
#> [4,] 4.266262 4.567848
#> [5,] 4.598126 4.299049
#> [6,] 4.178060 4.310285
#> [7,] 4.293826 4.500432
#> [8,] 5.141125 4.823682
#> [9,] 5.073870 4.722558
#> [10,] 4.431092 4.674157
#> [11,] 4.347299 4.382887
#> [12,] 4.187431 4.644771
#> [13,] 4.379272 4.494382
#> [14,] 4.788313 4.608470
#> [15,] 4.075524 4.186690
#> [16,] 4.952040 4.323250
#> ACTTACTCACTTCGAA-500.1.2 ACTTACTCAGCCAATT-500.1.2
#> [1,] 4.972449 4.588546
#> [2,] 4.757143 4.164317
#> [3,] 4.395918 4.133040
#> [4,] 4.761224 4.152863
#> [5,] 4.717347 4.533921
#> [6,] 4.466327 4.104846
#> [7,] 3.945918 4.123789
#> [8,] 5.360204 4.787225
#> [9,] 4.265306 4.527753
#> [10,] 4.333673 4.101762
#> [11,] 4.384694 4.040529
#> [12,] 4.418367 4.066960
#> [13,] 4.575510 4.530837
#> [14,] 4.465306 4.201762
#> [15,] 4.177551 4.061233
#> [16,] 3.995918 4.191189
#> ACTTGTTCAAGCCGTC-500.1.2 AGAATAGAGCCGATTT-500.1.2
#> [1,] 4.611159 4.354776
#> [2,] 3.892704 4.530214
#> [3,] 4.210300 3.980507
#> [4,] 4.333047 3.813840
#> [5,] 4.609442 4.223197
#> [6,] 4.095279 4.211501
#> [7,] 4.181116 4.281676
#> [8,] 4.843777 4.898635
#> [9,] 4.124464 4.734893
#> [10,] 4.166524 4.503899
#> [11,] 3.934764 4.168616
#> [12,] 4.115021 4.496101
#> [13,] 4.586266 4.669591
#> [14,] 3.954506 4.309942
#> [15,] 4.145064 4.702729
#> [16,] 4.369957 4.683236
#> AGACGTTAGTGAAGTT-500.1.2 AGAGCTTCACCGAATT-500.1.2
#> [1,] 4.418906 4.329502
#> [2,] 4.306766 4.213602
#> [3,] 4.560704 4.162835
#> [4,] 4.219648 4.187739
#> [5,] 4.576460 4.349617
#> [6,] 4.102873 4.532567
#> [7,] 4.078777 4.622605
#> [8,] 5.092678 4.782567
#> [9,] 4.331789 4.641762
#> [10,] 4.225209 4.001916
#> [11,] 4.256719 4.612069
#> [12,] 4.438369 4.525862
#> [13,] 4.363299 4.482759
#> [14,] 4.058387 4.368774
#> [15,] 4.103800 4.133142
#> [16,] 4.529194 4.741379
#> AGAGTGGTCAAGAAGT-500.1.2 AGATTGCCACCTATCC-500.1.2
#> [1,] 4.417207 4.303887
#> [2,] 4.109605 4.696820
#> [3,] 4.341780 4.130742
#> [4,] 4.124926 4.453710
#> [5,] 4.901591 4.313074
#> [6,] 4.141426 4.118021
#> [7,] 4.040071 4.103887
#> [8,] 5.273424 4.628269
#> [9,] 5.277549 4.917314
#> [10,] 4.055981 4.635336
#> [11,] 4.360047 4.263604
#> [12,] 4.366529 4.261484
#> [13,] 4.743076 4.561131
#> [14,] 4.338244 4.558304
#> [15,] 3.962876 4.804240
#> [16,] 4.642310 4.450883
#> AGCATACCACATTAGC-500.1.2 AGCGGTCCACCGTTGG-500.1.2
#> [1,] 4.136924 4.332524
#> [2,] 4.892927 4.064563
#> [3,] 4.337443 4.564563
#> [4,] 4.414666 4.278641
#> [5,] 3.938352 4.835922
#> [6,] 4.135626 4.897087
#> [7,] 4.060999 4.241262
#> [8,] 4.743024 4.975728
#> [9,] 5.275795 4.718447
#> [10,] 5.257625 4.522816
#> [11,] 4.182998 4.842233
#> [12,] 3.971447 4.215534
#> [13,] 4.530175 4.182524
#> [14,] 4.373783 4.772330
#> [15,] 4.961713 4.211650
#> [16,] 4.040234 4.548544
#> AGCGGTCGTCTTGATG-500.1.2 AGCGGTCGTCTTGCGG-500.1.2
#> [1,] 4.496441 4.693916
#> [2,] 4.336299 4.288023
#> [3,] 4.330961 4.029468
#> [4,] 4.451957 4.065589
#> [5,] 4.263345 4.832700
#> [6,] 4.465302 4.417300
#> [7,] 4.509786 4.399240
#> [8,] 5.094306 5.096958
#> [9,] 4.847865 4.721483
#> [10,] 4.353203 4.672053
#> [11,] 4.374555 4.346008
#> [12,] 4.378114 4.476236
#> [13,] 4.410142 4.850760
#> [14,] 4.383452 4.514259
#> [15,] 4.491993 3.981939
#> [16,] 4.501779 4.659696
#> AGCGTCGAGCAGACTG-500.1.2 AGCTCTCAGTCCTCCT-500.1.2
#> [1,] 4.431455 4.630747
#> [2,] 4.253154 4.214799
#> [3,] 4.339781 4.444684
#> [4,] 4.300252 4.193966
#> [5,] 4.434819 4.373563
#> [6,] 4.645080 4.551006
#> [7,] 4.164003 4.408764
#> [8,] 4.635828 4.964799
#> [9,] 4.711522 4.640086
#> [10,] 4.339781 4.422414
#> [11,] 4.401177 4.234914
#> [12,] 4.470984 4.434626
#> [13,] 4.863751 4.396552
#> [14,] 4.236333 4.541667
#> [15,] 4.144659 3.931034
#> [16,] 4.639193 4.542385
#> AGGCCACCACAGATTC-500.1.2 AGGGAGTCAAATTGCC-500.1.2
#> [1,] 4.438783 4.817401
#> [2,] 4.400000 5.022556
#> [3,] 4.330798 3.977444
#> [4,] 4.302662 4.611171
#> [5,] 4.552852 4.504834
#> [6,] 4.571103 4.980666
#> [7,] 4.362738 4.162191
#> [8,] 4.857795 4.671321
#> [9,] 4.796198 4.349087
#> [10,] 4.349049 5.038668
#> [11,] 4.390114 4.319012
#> [12,] 4.626616 4.323308
#> [13,] 4.355133 4.674544
#> [14,] 4.413688 4.252417
#> [15,] 4.057795 4.049409
#> [16,] 4.186312 4.317938
#> AGGGAGTCACCAGTTA-500.1.2 AGGGATGTCTATGTGG-500.1.2
#> [1,] 4.532642 4.202316
#> [2,] 4.476684 4.472071
#> [3,] 4.003109 4.361035
#> [4,] 4.401036 4.299728
#> [5,] 4.496373 4.300409
#> [6,] 4.179275 4.423025
#> [7,] 4.236269 4.250000
#> [8,] 5.236269 4.788828
#> [9,] 4.696373 4.895095
#> [10,] 4.451813 4.757493
#> [11,] 4.286010 4.151226
#> [12,] 4.430052 4.386240
#> [13,] 4.624870 4.512262
#> [14,] 4.212435 4.461853
#> [15,] 4.454922 4.500681
#> [16,] 4.607254 4.094005
#> AGGTCCGTCCCAACGG-500.1.2 AGTTGGTAGATCCGAG-500.1.2
#> [1,] 4.304378 4.128655
#> [2,] 4.670999 4.411306
#> [3,] 4.582763 4.516569
#> [4,] 4.497948 4.252437
#> [5,] 4.079343 4.871345
#> [6,] 4.188782 3.972710
#> [7,] 4.155267 4.016569
#> [8,] 4.840629 4.855750
#> [9,] 5.018468 4.721248
#> [10,] 4.286594 4.343080
#> [11,] 4.078659 4.410331
#> [12,] 4.325581 4.392788
#> [13,] 4.273598 4.947368
#> [14,] 4.437756 3.986355
#> [15,] 4.181943 3.954191
#> [16,] 4.304378 4.514620
#> ATAACGCTCTCGATGA-500.1.2 ATAAGAGCATGCAATC-500.1.2
#> [1,] 4.574454 4.444724
#> [2,] 4.505464 4.003769
#> [3,] 4.452186 4.589824
#> [4,] 4.565574 4.519472
#> [5,] 4.606557 4.641332
#> [6,] 4.331284 4.130025
#> [7,] 4.582650 4.013819
#> [8,] 4.758880 5.035804
#> [9,] 4.602459 4.712940
#> [10,] 4.395492 4.442211
#> [11,] 4.385246 4.525126
#> [12,] 4.462432 4.683417
#> [13,] 4.476776 4.599246
#> [14,] 3.987022 4.209799
#> [15,] 4.653005 3.701005
#> [16,] 4.338115 4.141332
#> ATAAGAGGTTTACTCT-500.1.2 ATCGAGTAGAGTCGGT-500.1.2
#> [1,] 4.677340 5.047664
#> [2,] 4.650246 4.300286
#> [3,] 3.751232 4.251668
#> [4,] 4.295567 4.216397
#> [5,] 4.716749 4.650143
#> [6,] 4.134236 4.466158
#> [7,] 3.986453 3.922784
#> [8,] 4.862069 4.998093
#> [9,] 4.501232 4.643470
#> [10,] 4.785714 4.140133
#> [11,] 4.506158 4.228789
#> [12,] 4.668719 4.215443
#> [13,] 4.424877 5.028599
#> [14,] 4.112069 4.526215
#> [15,] 3.689655 4.148713
#> [16,] 4.296798 3.989514
#> ATCGAGTAGCCCGAAA-500.1.2 ATCTACTCAAGTAGTA-500.1.2
#> [1,] 4.242215 4.731111
#> [2,] 4.496540 4.462222
#> [3,] 4.638985 4.245556
#> [4,] 4.389273 4.257778
#> [5,] 4.587082 4.641111
#> [6,] 4.310842 4.466667
#> [7,] 4.059977 4.152222
#> [8,] 4.923299 4.866667
#> [9,] 4.931373 5.211111
#> [10,] 4.301038 4.364444
#> [11,] 4.086505 4.393333
#> [12,] 4.440600 4.445556
#> [13,] 4.236448 4.765556
#> [14,] 4.256632 4.527778
#> [15,] 4.237024 4.077778
#> [16,] 4.696078 4.663333
#> ATGCGATTCCAGATCA-500.1.2 ATTACTCCAGCAGTTT-500.1.2
#> [1,] 4.335979 4.599144
#> [2,] 4.177249 3.934023
#> [3,] 4.619048 4.030670
#> [4,] 4.630291 4.316690
#> [5,] 4.277116 4.602354
#> [6,] 4.390873 3.859130
#> [7,] 4.270503 4.738944
#> [8,] 4.695106 4.347718
#> [9,] 4.781746 4.194009
#> [10,] 4.433201 4.182596
#> [11,] 4.125661 4.317760
#> [12,] 4.569444 4.274608
#> [13,] 4.500661 4.349501
#> [14,] 4.609788 4.458631
#> [15,] 4.076720 3.923680
#> [16,] 4.387566 4.206491
#> ATTCTACGTCACTGGC-500.1.2 ATTGGACCAAGCGCTC-500.1.2
#> [1,] 4.267475 4.259475
#> [2,] 4.218260 4.470554
#> [3,] 4.421541 4.260641
#> [4,] 4.179743 4.269971
#> [5,] 4.422967 4.433236
#> [6,] 4.330243 4.333528
#> [7,] 4.050642 4.489796
#> [8,] 4.863053 4.773761
#> [9,] 4.713267 4.581341
#> [10,] 4.460770 4.506706
#> [11,] 4.302425 4.472886
#> [12,] 4.453638 4.837318
#> [13,] 4.311698 4.423324
#> [14,] 4.170471 4.417493
#> [15,] 4.136234 4.591254
#> [16,] 4.458631 4.574927
#> ATTGGTGCACAAGTAA-500.1.2 ATTTCTGCACTGAAGG-500.1.2
#> [1,] 4.471562 4.596175
#> [2,] 3.972642 4.253093
#> [3,] 4.110151 4.248594
#> [4,] 4.020878 4.571429
#> [5,] 4.825054 4.950506
#> [6,] 4.153348 4.343082
#> [7,] 4.425486 4.140607
#> [8,] 4.650108 5.069741
#> [9,] 4.146148 5.365579
#> [10,] 4.071274 4.284589
#> [11,] 3.847372 4.249719
#> [12,] 4.334773 4.532058
#> [13,] 4.154788 4.602925
#> [14,] 4.335493 4.643420
#> [15,] 3.930886 3.791901
#> [16,] 3.894888 4.591676
#> ATTTCTGTCGAGAGCA-500.1.2 CAACCTCGTTAGAACA-500.1.2
#> [1,] 4.705417 4.557398
#> [2,] 4.028074 4.179847
#> [3,] 4.218664 4.243622
#> [4,] 4.426255 4.113520
#> [5,] 4.654804 4.387755
#> [6,] 4.103994 3.942602
#> [7,] 4.322657 4.158163
#> [8,] 4.616449 4.669643
#> [9,] 4.372479 4.383929
#> [10,] 3.961250 3.961735
#> [11,] 4.066825 4.131378
#> [12,] 4.217082 4.401786
#> [13,] 4.480822 4.438776
#> [14,] 4.538157 3.853316
#> [15,] 4.137208 4.669643
#> [16,] 4.308027 4.735969
#> CAAGTTGCAGCTGGCT-500.1.2 CACACAAAGATATGGT-500.1.2
#> [1,] 4.659439 3.963010
#> [2,] 4.285714 4.137755
#> [3,] 4.201531 4.238520
#> [4,] 4.589286 4.103316
#> [5,] 4.823980 4.558673
#> [6,] 4.298469 4.434949
#> [7,] 4.054847 4.140306
#> [8,] 5.359694 5.176020
#> [9,] 4.750000 5.167092
#> [10,] 4.179847 4.218112
#> [11,] 4.454082 4.360969
#> [12,] 4.494898 4.612245
#> [13,] 4.502551 3.992347
#> [14,] 4.401786 4.641582
#> [15,] 3.895408 4.195153
#> [16,] 4.336735 4.471939
#> CACCACTTCTGATTCT-500.1.2 CACCTTGAGGTGTTAA-500.1.2
#> [1,] 4.419009 3.966227
#> [2,] 4.659304 4.467875
#> [3,] 4.526104 4.581549
#> [4,] 4.414324 4.435750
#> [5,] 4.291834 4.363262
#> [6,] 4.612450 4.446458
#> [7,] 4.265730 4.303130
#> [8,] 4.951138 4.579077
#> [9,] 4.838688 4.702636
#> [10,] 4.565596 4.196870
#> [11,] 4.568273 4.392916
#> [12,] 4.609772 4.059308
#> [13,] 4.533467 4.742998
#> [14,] 4.579652 4.401153
#> [15,] 4.136546 3.861614
#> [16,] 4.204819 4.874794
#> CACTCCAAGGGCTTGA-500.1.2 CACTCCATCGCGTTTC-500.1.2
#> [1,] 4.165372 4.848564
#> [2,] 4.087125 4.182768
#> [3,] 4.548835 4.120104
#> [4,] 4.369589 4.424282
#> [5,] 4.609878 4.640992
#> [6,] 4.428413 4.475196
#> [7,] 4.038291 4.063969
#> [8,] 5.191454 5.105744
#> [9,] 5.391232 4.881201
#> [10,] 4.497780 4.113577
#> [11,] 4.399001 4.194517
#> [12,] 4.127081 4.244125
#> [13,] 4.158158 4.911227
#> [14,] 4.445061 4.121410
#> [15,] 4.104883 4.061358
#> [16,] 4.546060 4.864230
#> CAGAATCCACCTCGGA-500.1.2 CAGAGAGAGCGATTCT-500.1.2
#> [1,] 4.773659 4.318140
#> [2,] 5.252683 4.374884
#> [3,] 4.311220 4.403721
#> [4,] 4.665366 3.950698
#> [5,] 4.765854 4.467907
#> [6,] 5.026341 4.239070
#> [7,] 4.276098 4.120930
#> [8,] 4.737561 4.910698
#> [9,] 4.252683 4.790698
#> [10,] 4.723902 4.070698
#> [11,] 4.416585 4.211163
#> [12,] 4.390244 4.345116
#> [13,] 4.609756 4.883721
#> [14,] 4.552195 4.151628
#> [15,] 3.929756 4.113488
#> [16,] 4.069268 4.314419
#> CAGATCAAGCAGACTG-500.1.2 CAGCATACACGTTGGC-500.1.2
#> [1,] 4.531186 4.365938
#> [2,] 4.442084 4.023015
#> [3,] 4.723098 3.713464
#> [4,] 4.309801 4.135788
#> [5,] 4.729267 4.344074
#> [6,] 4.653187 4.989643
#> [7,] 4.263879 3.953970
#> [8,] 5.117204 4.676640
#> [9,] 4.617546 4.478711
#> [10,] 4.630569 4.200230
#> [11,] 4.372173 4.001151
#> [12,] 4.481151 4.331415
#> [13,] 4.335161 4.222094
#> [14,] 4.525703 5.141542
#> [15,] 4.054832 4.395857
#> [16,] 4.310487 4.668585
#> CAGTAACCATCTGGTA-500.1.2 CAGTCCTGTCTTCTCG-500.1.2
#> [1,] 4.443615 4.348684
#> [2,] 4.150912 4.224781
#> [3,] 4.419569 4.356360
#> [4,] 4.463516 4.036184
#> [5,] 4.388060 4.058114
#> [6,] 4.218905 4.346491
#> [7,] 4.551410 4.541667
#> [8,] 5.155887 4.728070
#> [9,] 4.658375 4.664474
#> [10,] 4.355721 4.190789
#> [11,] 4.125207 4.331140
#> [12,] 4.599502 4.466009
#> [13,] 4.747927 4.320175
#> [14,] 4.013267 4.365132
#> [15,] 4.299337 4.135965
#> [16,] 4.425373 4.980263
#> CATATGGCAATCGGTT-500.1.2 CATATGGTCGCTAGCG-500.1.2
#> [1,] 4.614535 4.318318
#> [2,] 4.118675 3.968468
#> [3,] 4.065317 4.396021
#> [4,] 4.131555 4.384760
#> [5,] 4.532659 4.736486
#> [6,] 4.195952 4.595721
#> [7,] 4.139834 4.194820
#> [8,] 4.964121 4.876502
#> [9,] 4.781049 4.731982
#> [10,] 4.105796 4.516892
#> [11,] 4.045078 4.691441
#> [12,] 4.818767 4.464715
#> [13,] 5.055198 4.340841
#> [14,] 4.103036 4.604730
#> [15,] 3.979761 4.135511
#> [16,] 4.522539 4.547673
#> CATCAAGCAAGCCCAC-500.1.2 CATTATCTCCTCAACC-500.1.2
#> [1,] 4.574094 4.176802
#> [2,] 4.317234 4.138514
#> [3,] 4.217344 4.272523
#> [4,] 4.215148 4.058559
#> [5,] 4.518112 4.658784
#> [6,] 4.511526 4.399775
#> [7,] 4.246981 4.075450
#> [8,] 5.103183 5.087838
#> [9,] 4.614709 4.617117
#> [10,] 4.581778 4.398649
#> [11,] 4.380900 4.310811
#> [12,] 4.289791 4.281532
#> [13,] 4.360044 4.561937
#> [14,] 4.780461 4.055180
#> [15,] 4.442371 4.449324
#> [16,] 4.425906 4.558559
#> CATTCGCAGTAGGCCA-500.1.2 CATTCGCTCACATAGC-500.1.2
#> [1,] 3.738520 4.383604
#> [2,] 3.934949 4.556845
#> [3,] 3.854592 4.351121
#> [4,] 4.190051 4.445476
#> [5,] 3.956633 4.535189
#> [6,] 4.829082 4.478732
#> [7,] 3.644133 4.262954
#> [8,] 4.596939 4.873937
#> [9,] 4.628827 4.586234
#> [10,] 4.165816 4.561485
#> [11,] 3.831633 4.375870
#> [12,] 4.432398 4.470224
#> [13,] 4.117347 4.569992
#> [14,] 5.159439 4.954370
#> [15,] 3.963010 4.184068
#> [16,] 4.853316 4.466357
#> CCAATCCCAAGGACTG-500.1.2 CCAATCCGTTCGCTAA-500.1.2
#> [1,] 4.561549 4.442700
#> [2,] 4.215768 4.153846
#> [3,] 4.088520 4.301413
#> [4,] 4.385892 4.382261
#> [5,] 4.331950 4.715856
#> [6,] 4.330567 4.378336
#> [7,] 4.408022 4.046311
#> [8,] 4.869986 5.114600
#> [9,] 4.691563 4.735479
#> [10,] 4.424620 4.470173
#> [11,] 4.005533 4.284929
#> [12,] 4.710927 4.235479
#> [13,] 4.838174 4.498430
#> [14,] 4.016598 4.610675
#> [15,] 4.513140 4.262951
#> [16,] 4.683264 4.357928
#> CCACGGAGTGTTGAGG-500.1.2 CCACGGATCCACGACG-500.1.2
#> [1,] 4.241170 4.610932
#> [2,] 3.839404 4.331994
#> [3,] 4.507174 4.846463
#> [4,] 4.967991 4.530547
#> [5,] 4.412804 4.574759
#> [6,] 4.525938 4.384244
#> [7,] 3.720199 4.278939
#> [8,] 5.234547 5.181672
#> [9,] 5.721302 4.265273
#> [10,] 5.006071 4.610129
#> [11,] 4.133002 4.384244
#> [12,] 3.953642 4.706592
#> [13,] 3.976269 4.273312
#> [14,] 4.398455 4.409968
#> [15,] 3.861479 4.469453
#> [16,] 4.222406 4.154341
#> CCAGCGACAATTGCTG-500.1.2 CCATTCGAGATGTGGC-500.1.2
#> [1,] 4.303378 4.631016
#> [2,] 4.217336 4.051337
#> [3,] 4.723391 4.258824
#> [4,] 4.378585 4.414973
#> [5,] 4.493308 4.486631
#> [6,] 4.386233 4.445989
#> [7,] 4.145315 4.447059
#> [8,] 4.906947 4.961497
#> [9,] 4.582537 4.611765
#> [10,] 4.346718 4.155080
#> [11,] 4.458254 4.206417
#> [12,] 4.347992 4.471658
#> [13,] 4.458891 4.804278
#> [14,] 4.416826 4.271658
#> [15,] 4.225621 4.282353
#> [16,] 4.616316 4.796791
#> CCATTCGTCGAACGGA-500.1.2 CCCAGTTGTGCGCTTG-500.1.2
#> [1,] 4.271724 4.182091
#> [2,] 4.369655 4.188702
#> [3,] 4.297931 4.572115
#> [4,] 4.622069 4.765024
#> [5,] 4.564138 4.326923
#> [6,] 4.347586 4.200120
#> [7,] 4.219310 4.283654
#> [8,] 4.845517 4.704928
#> [9,] 4.417931 4.988582
#> [10,] 4.216552 4.664663
#> [11,] 4.640000 4.196514
#> [12,] 4.565517 4.334736
#> [13,] 4.540690 3.928486
#> [14,] 4.918621 4.591346
#> [15,] 4.631724 4.392428
#> [16,] 4.114483 4.235577
#> CCCAGTTTCAATCACG-500.1.2 CCCTCCTGTCCCGACA-500.1.2
#> [1,] 4.445592 4.716738
#> [2,] 4.619539 4.673820
#> [3,] 4.118348 4.321888
#> [4,] 4.408261 4.752504
#> [5,] 4.285941 4.759657
#> [6,] 4.575854 4.244635
#> [7,] 4.146942 4.090129
#> [8,] 4.652105 5.251788
#> [9,] 4.712470 4.994278
#> [10,] 4.373312 4.062947
#> [11,] 4.303415 4.091559
#> [12,] 4.438443 4.709585
#> [13,] 4.167593 4.523605
#> [14,] 4.270056 4.429185
#> [15,] 4.424146 4.537911
#> [16,] 4.724384 4.472103
#> CCTACACGTGTGGTTT-500.1.2 CCTAGCTGTGGAAAGA-500.1.2
#> [1,] 4.205660 4.694203
#> [2,] 4.014151 4.210870
#> [3,] 4.114151 4.550725
#> [4,] 4.339623 4.328261
#> [5,] 4.211321 4.395652
#> [6,] 4.833019 4.447101
#> [7,] 4.104717 3.834783
#> [8,] 4.638679 5.129710
#> [9,] 4.910377 4.571014
#> [10,] 4.119811 4.250725
#> [11,] 4.479245 4.173188
#> [12,] 4.375472 4.499275
#> [13,] 4.151887 5.097826
#> [14,] 5.077358 4.187681
#> [15,] 4.081132 4.318116
#> [16,] 4.916038 4.238406
#> CCTAGCTTCACGGTTA-500.1.2 CCTCAGTTCTGGTTCC-500.1.2
#> [1,] 4.189501 4.539632
#> [2,] 4.190781 4.397118
#> [3,] 4.038412 4.287430
#> [4,] 3.889885 4.126501
#> [5,] 4.590269 4.803843
#> [6,] 4.920615 4.792634
#> [7,] 4.044814 4.022418
#> [8,] 4.829706 4.998399
#> [9,] 4.641485 4.930344
#> [10,] 4.060179 3.959167
#> [11,] 4.039693 4.280224
#> [12,] 4.290653 4.556445
#> [13,] 4.494238 4.879904
#> [14,] 4.770807 4.142514
#> [15,] 3.987196 4.017614
#> [16,] 5.079385 4.485989
#> CCTCTGAGTTGTGGAG-500.1.2 CCTTACGAGCGTAGTG-500.1.2
#> [1,] 4.320977 4.882653
#> [2,] 4.284751 4.427296
#> [3,] 4.424600 4.607143
#> [4,] 4.104465 4.063776
#> [5,] 4.483572 4.415816
#> [6,] 4.165122 4.345663
#> [7,] 4.363100 3.838010
#> [8,] 5.171019 5.054847
#> [9,] 4.775063 4.568878
#> [10,] 4.518955 4.399235
#> [11,] 4.321820 4.100765
#> [12,] 4.523168 4.308673
#> [13,] 4.647852 4.191327
#> [14,] 4.583825 4.571429
#> [15,] 4.115417 4.042092
#> [16,] 4.486099 4.442602
#> CCTTTCTGTGACGGTA-500.1.2 CGAACATAGACTAGGC-500.1.2
#> [1,] 4.554736 4.633011
#> [2,] 4.139535 4.402985
#> [3,] 4.073738 4.278314
#> [4,] 3.987521 4.106234
#> [5,] 4.502552 4.528534
#> [6,] 4.242768 4.339772
#> [7,] 4.187181 4.483758
#> [8,] 4.980147 5.071993
#> [9,] 4.879183 4.522388
#> [10,] 4.073171 4.175593
#> [11,] 4.167328 4.257243
#> [12,] 4.435621 4.495171
#> [13,] 4.670448 4.765584
#> [14,] 4.283040 3.980685
#> [15,] 3.868973 4.320457
#> [16,] 4.381168 4.538191
#> CGAACATCAGAAGCAC-500.1.2 CGAGAAGCACAGGCCT-500.1.2
#> [1,] 4.342419 4.052083
#> [2,] 3.978989 4.138889
#> [3,] 4.013629 4.217593
#> [4,] 4.231687 4.144676
#> [5,] 4.879614 4.217593
#> [6,] 3.841567 4.085648
#> [7,] 4.660420 4.303241
#> [8,] 4.320273 4.737269
#> [9,] 4.057922 4.855324
#> [10,] 3.904032 3.858796
#> [11,] 4.059057 4.276620
#> [12,] 4.214651 4.231481
#> [13,] 4.398637 4.626157
#> [14,] 4.119818 3.606481
#> [15,] 4.322544 4.012731
#> [16,] 4.133447 4.237269
#> CGCGGTACAGTCTTCC-500.1.2 CGCGTTTAGAGCTTCT-500.1.2
#> [1,] 4.513768 4.761768
#> [2,] 4.569510 4.243996
#> [3,] 4.220954 4.615754
#> [4,] 4.063130 4.250720
#> [5,] 4.570853 4.546590
#> [6,] 3.999328 4.229587
#> [7,] 4.456682 4.047070
#> [8,] 4.613835 4.989433
#> [9,] 4.394896 4.838617
#> [10,] 4.302888 4.345821
#> [11,] 4.483546 4.434198
#> [12,] 4.570181 4.372719
#> [13,] 4.609134 4.872238
#> [14,] 4.024849 4.276657
#> [15,] 4.676964 3.990394
#> [16,] 4.456011 4.237272
#> CGCGTTTCACGTGAGA-500.1.2 CGCTATCCACAGTCGC-500.1.2
#> [1,] 4.513912 4.331288
#> [2,] 4.825696 4.582822
#> [3,] 3.946809 4.019281
#> [4,] 4.564648 4.678352
#> [5,] 4.524550 4.519720
#> [6,] 4.612930 4.400526
#> [7,] 3.956628 4.390009
#> [8,] 4.659574 4.677476
#> [9,] 4.135843 4.832603
#> [10,] 4.837152 4.276950
#> [11,] 4.123568 4.278703
#> [12,] 4.365794 4.357581
#> [13,] 4.723404 4.501315
#> [14,] 4.416530 4.717791
#> [15,] 3.727496 4.248904
#> [16,] 4.315057 4.232252
#> CGGACACCATAAGACA-500.1.2 CGGAGCTGTACCCAAT-500.1.2
#> [1,] 4.534716 4.181485
#> [2,] 4.398557 4.347388
#> [3,] 4.887286 4.073327
#> [4,] 4.783589 4.500458
#> [5,] 4.685302 4.264895
#> [6,] 4.657349 4.574702
#> [7,] 4.338142 4.052246
#> [8,] 5.145176 5.102658
#> [9,] 4.787196 4.312557
#> [10,] 4.438233 4.340972
#> [11,] 4.256087 4.649863
#> [12,] 4.687106 4.585701
#> [13,] 4.145176 4.134739
#> [14,] 4.359784 4.639780
#> [15,] 4.021641 4.714940
#> [16,] 4.275924 4.350137
#> CGTAGCGTCAAACCGT-500.1.2 CGTAGCGTCTTGTCAT-500.1.2
#> [1,] 4.615012 4.924802
#> [2,] 4.444310 4.385224
#> [3,] 4.665860 4.255937
#> [4,] 4.376513 4.317942
#> [5,] 4.628329 4.374670
#> [6,] 3.995157 4.366755
#> [7,] 3.981840 4.240106
#> [8,] 4.739709 4.996042
#> [9,] 4.802663 4.105541
#> [10,] 4.140436 4.011873
#> [11,] 4.386199 4.134565
#> [12,] 4.732446 4.467018
#> [13,] 4.875303 4.932718
#> [14,] 4.434625 4.266491
#> [15,] 3.993947 3.930079
#> [16,] 4.909201 4.145119
#> CGTCAGGAGGCTAGCA-500.1.2 CGTCAGGCAACGCACC-500.1.2
#> [1,] 4.563838 4.438261
#> [2,] 4.349722 4.259130
#> [3,] 4.310864 4.286957
#> [4,] 4.205393 4.304348
#> [5,] 4.465504 4.549565
#> [6,] 4.630452 4.622609
#> [7,] 4.070579 4.144348
#> [8,] 4.802538 5.104348
#> [9,] 4.473434 4.427826
#> [10,] 4.252974 4.486957
#> [11,] 4.279937 4.336522
#> [12,] 4.715305 4.302609
#> [13,] 4.478192 4.537391
#> [14,] 4.337827 4.580870
#> [15,] 4.367962 4.242609
#> [16,] 4.473434 4.734783
#> CGTGTAAGTGCCTTGG-500.1.2 CGTGTCTGTAAGGGAA-500.1.2
#> [1,] 4.491859 4.310013
#> [2,] 4.610111 4.077022
#> [3,] 4.473008 4.529525
#> [4,] 4.161954 4.256098
#> [5,] 4.215081 4.325417
#> [6,] 4.586975 4.286906
#> [7,] 4.423308 4.362644
#> [8,] 4.892031 4.881900
#> [9,] 4.894602 4.200257
#> [10,] 4.729220 4.639923
#> [11,] 4.366752 4.193838
#> [12,] 4.263068 4.577022
#> [13,] 4.571551 4.111682
#> [14,] 4.393316 4.001284
#> [15,] 4.293916 4.210526
#> [16,] 4.509854 4.335045
#> CGTTAGACAAGCGTAG-500.1.2 CTAATGGAGACTTTCG-500.1.2
#> [1,] 4.376775 4.540385
#> [2,] 4.118630 4.296154
#> [3,] 4.184628 4.280769
#> [4,] 4.187970 4.108654
#> [5,] 4.644946 4.262500
#> [6,] 4.103592 4.442308
#> [7,] 4.337510 4.300000
#> [8,] 4.588137 5.024038
#> [9,] 4.298246 4.788462
#> [10,] 4.375104 4.064423
#> [11,] 4.333333 4.087500
#> [12,] 4.605681 4.784615
#> [13,] 4.423559 4.403846
#> [14,] 4.224728 4.222115
#> [15,] 4.300752 4.239423
#> [16,] 4.502924 4.778846
#> CTACACCAGGCAGTCA-500.1.2 CTACATTCATATGCTG-500.1.2
#> [1,] 4.338813 4.431158
#> [2,] 4.497717 4.203430
#> [3,] 4.837443 4.212959
#> [4,] 4.586301 4.313006
#> [5,] 4.586301 4.574083
#> [6,] 4.277626 3.953788
#> [7,] 4.141553 4.261077
#> [8,] 4.946119 5.019057
#> [9,] 4.943379 4.333016
#> [10,] 4.269406 4.158647
#> [11,] 4.416438 4.200572
#> [12,] 4.157078 4.304907
#> [13,] 4.515068 4.466889
#> [14,] 4.337900 4.014293
#> [15,] 4.050228 4.217723
#> [16,] 4.346119 4.222963
#> CTACCCAGTGGTAACG-500.1.2 CTAGAGTCATCGGACC-500.1.2
#> [1,] 4.469219 4.710086
#> [2,] 4.448198 4.137861
#> [3,] 4.288288 4.297010
#> [4,] 4.501502 4.508363
#> [5,] 4.289790 4.480487
#> [6,] 4.336336 4.426761
#> [7,] 4.200450 3.977192
#> [8,] 4.737988 5.155601
#> [9,] 4.672673 4.772428
#> [10,] 4.597598 4.271161
#> [11,] 4.515766 4.345160
#> [12,] 4.625375 4.400405
#> [13,] 4.473724 4.896604
#> [14,] 4.566066 4.487582
#> [15,] 4.171171 4.102382
#> [16,] 4.306306 4.506336
#> CTCACACAGAAACGAG-500.1.2 CTCGAAACACAGACTT-500.1.2
#> [1,] 4.291411 4.285446
#> [2,] 4.228834 4.310798
#> [3,] 4.584663 4.299531
#> [4,] 4.513497 4.288263
#> [5,] 4.469325 4.585915
#> [6,] 4.329448 4.310798
#> [7,] 4.153374 4.264789
#> [8,] 4.926994 4.475117
#> [9,] 4.673006 4.287324
#> [10,] 4.318405 4.163380
#> [11,] 4.207362 4.162441
#> [12,] 4.395092 4.056338
#> [13,] 4.433129 4.166197
#> [14,] 4.480368 4.169014
#> [15,] 4.274847 4.211268
#> [16,] 4.522086 4.439437
#> CTCGGAGGTTTAGCTG-500.1.2 CTCGGAGTCGGAATCT-500.1.2
#> [1,] 4.664234 4.424051
#> [2,] 4.621350 4.660529
#> [3,] 4.251825 4.448792
#> [4,] 4.305657 4.487917
#> [5,] 4.395073 4.493671
#> [6,] 4.456204 4.296893
#> [7,] 4.308394 4.417146
#> [8,] 4.760036 4.813003
#> [9,] 4.687044 4.620253
#> [10,] 4.625000 4.580552
#> [11,] 4.470803 4.510357
#> [12,] 4.279197 4.603567
#> [13,] 4.466241 4.596087
#> [14,] 4.684307 4.355581
#> [15,] 4.333029 4.462025
#> [16,] 4.650547 4.510932
#> CTCTAATAGGATCGCA-500.1.2 CTCTACGGTCGTGGCT-500.1.2
#> [1,] 4.230999 4.155003
#> [2,] 4.147541 4.458470
#> [3,] 4.423746 4.381949
#> [4,] 4.260308 4.589274
#> [5,] 4.731744 4.456508
#> [6,] 5.073025 4.316547
#> [7,] 4.164928 4.418574
#> [8,] 4.752608 4.812296
#> [9,] 4.637854 4.392413
#> [10,] 4.575758 4.584696
#> [11,] 4.780427 4.330281
#> [12,] 4.313462 4.463702
#> [13,] 3.990065 4.503597
#> [14,] 4.823646 4.281884
#> [15,] 4.248385 4.534336
#> [16,] 4.494287 4.024853
#> CTGAAGTCACGCATCG-500.1.2 CTGCTGTTCGGAGCAA-500.1.2
#> [1,] 4.164879 4.229750
#> [2,] 4.334839 4.398135
#> [3,] 4.505929 4.543446
#> [4,] 4.307171 4.585174
#> [5,] 4.441558 4.594993
#> [6,] 4.573687 4.125675
#> [7,] 4.287408 4.203240
#> [8,] 4.851496 5.275896
#> [9,] 4.849238 4.832106
#> [10,] 4.451722 4.405007
#> [11,] 4.285714 4.386843
#> [12,] 4.375494 4.360825
#> [13,] 4.313947 4.796269
#> [14,] 4.227555 4.106529
#> [15,] 4.239977 4.039764
#> [16,] 4.730096 4.318606
#> CTGGTCTGTTATCCGA-500.1.2 CTGTTTACAGAAGCAC-500.1.2
#> [1,] 4.373989 4.463696
#> [2,] 4.220286 4.408911
#> [3,] 4.296826 4.599010
#> [4,] 4.310516 4.555776
#> [5,] 4.159303 4.488449
#> [6,] 4.627878 4.277228
#> [7,] 4.237710 4.187129
#> [8,] 5.054760 4.988449
#> [9,] 4.767268 4.858746
#> [10,] 4.512134 4.225413
#> [11,] 4.360299 4.242574
#> [12,] 4.567517 4.310891
#> [13,] 4.462974 4.224752
#> [14,] 4.616055 4.482178
#> [15,] 4.407592 4.375908
#> [16,] 4.228376 4.462046
#> CTTCTCTGTCTTCTCG-500.1.2 GAAATGATCTCTAAGG-500.1.2
#> [1,] 4.249064 4.410165
#> [2,] 4.294007 4.612293
#> [3,] 4.532772 4.532506
#> [4,] 4.154494 4.578605
#> [5,] 4.526217 4.571513
#> [6,] 4.192884 4.265366
#> [7,] 4.236891 4.431442
#> [8,] 5.113296 4.857565
#> [9,] 5.227528 4.459811
#> [10,] 4.215356 4.593972
#> [11,] 4.233146 4.489362
#> [12,] 4.446629 4.626478
#> [13,] 4.282772 4.400709
#> [14,] 4.677903 4.423759
#> [15,] 4.132022 4.596336
#> [16,] 4.708801 4.402482
#> GAACATCCATAGTAAG-500.1.2 GAACGGAAGGCTAGAC-500.1.2
#> [1,] 4.435574 4.441785
#> [2,] 4.420168 4.165397
#> [3,] 4.519608 4.332971
#> [4,] 4.103641 4.105550
#> [5,] 4.253501 4.366703
#> [6,] 4.168067 3.775843
#> [7,] 4.079832 4.085963
#> [8,] 4.976190 4.715996
#> [9,] 4.289916 4.660501
#> [10,] 4.453782 4.225245
#> [11,] 4.450980 4.316649
#> [12,] 4.338936 4.514690
#> [13,] 4.165266 4.529924
#> [14,] 4.413165 4.183896
#> [15,] 4.201681 4.087051
#> [16,] 4.505602 5.155604
#> GACACGCTCCGAATGT-500.1.2 GACGCGTCATGGTTGT-500.1.2
#> [1,] 4.312165 4.878713
#> [2,] 4.360465 3.870050
#> [3,] 4.051878 4.273515
#> [4,] 4.748658 4.178218
#> [5,] 4.294275 4.259901
#> [6,] 4.571556 4.547030
#> [7,] 4.349732 4.476485
#> [8,] 4.955277 4.849010
#> [9,] 4.865832 4.800743
#> [10,] 4.262970 4.073020
#> [11,] 4.176208 4.117574
#> [12,] 4.453488 4.363861
#> [13,] 4.779964 4.626238
#> [14,] 4.931127 4.264851
#> [15,] 4.255814 4.240099
#> [16,] 4.211091 4.535891
#> GACGCGTTCTTGGGTA-500.1.2 GACGTGCCATAAAGGT-500.1.2
#> [1,] 4.264049 4.873484
#> [2,] 4.505004 5.644714
#> [3,] 4.635104 4.482669
#> [4,] 4.318707 4.124783
#> [5,] 4.450346 4.305893
#> [6,] 4.149346 5.050260
#> [7,] 4.330254 4.343154
#> [8,] 4.918399 4.730503
#> [9,] 5.132410 3.617851
#> [10,] 4.236336 4.374350
#> [11,] 4.088530 4.865685
#> [12,] 4.317167 4.727903
#> [13,] 4.611239 4.099653
#> [14,] 4.578907 4.098787
#> [15,] 4.091609 4.110052
#> [16,] 4.398768 3.974003
#> GACTAACTCCAGTAGT-500.1.2 GACTACAAGATCGATA-500.1.2
#> [1,] 4.623506 4.617647
#> [2,] 4.392430 4.460784
#> [3,] 4.669323 4.167558
#> [4,] 4.403386 4.122103
#> [5,] 4.720120 4.540107
#> [6,] 4.638446 4.491087
#> [7,] 3.962151 4.335116
#> [8,] 5.278884 4.984848
#> [9,] 4.440239 4.845811
#> [10,] 4.249004 4.672906
#> [11,] 4.322709 4.434046
#> [12,] 4.492032 4.311943
#> [13,] 4.712151 5.017825
#> [14,] 4.412351 4.639929
#> [15,] 3.926295 4.040998
#> [16,] 4.500996 4.558824
#> GAGGTGAGTCTCCATC-500.1.2 GATCAGTCAGCTGCAC-500.1.2
#> [1,] 4.481383 4.411332
#> [2,] 4.430851 4.359088
#> [3,] 4.266844 4.350993
#> [4,] 4.351950 4.540839
#> [5,] 4.604610 4.311258
#> [6,] 4.605496 4.788815
#> [7,] 4.397163 4.486387
#> [8,] 5.164007 4.714496
#> [9,] 4.632092 4.427520
#> [10,] 4.801418 4.456954
#> [11,] 4.343085 4.498896
#> [12,] 4.448582 4.466519
#> [13,] 4.498227 4.450331
#> [14,] 4.632092 4.389257
#> [15,] 4.221631 4.426784
#> [16,] 4.659574 4.335541
#> GATCGCGCACACGCTG-500.1.2 GATTCAGAGGAGTAGA-500.1.2
#> [1,] 4.302880 4.574380
#> [2,] 4.461443 4.089532
#> [3,] 4.208424 4.188705
#> [4,] 4.269433 4.491736
#> [5,] 4.360793 5.012397
#> [6,] 4.397337 4.188705
#> [7,] 4.368535 3.966942
#> [8,] 4.874264 5.264463
#> [9,] 4.656550 4.895317
#> [10,] 4.467018 4.079890
#> [11,] 4.307526 4.059229
#> [12,] 4.419325 4.330579
#> [13,] 4.560545 4.545455
#> [14,] 4.371013 3.958678
#> [15,] 4.128523 4.111570
#> [16,] 4.494890 4.641873
#> GATTCAGCAAACTGCT-500.1.2 GCAAACTTCCGCTGTT-500.1.2
#> [1,] 4.327168 4.372694
#> [2,] 4.195376 4.185029
#> [3,] 4.319075 4.092778
#> [4,] 4.110983 4.458619
#> [5,] 4.182659 4.527148
#> [6,] 4.423121 4.227728
#> [7,] 4.506358 4.265156
#> [8,] 4.578035 4.931471
#> [9,] 4.573410 4.411703
#> [10,] 4.354913 4.360042
#> [11,] 4.363006 4.489193
#> [12,] 4.567630 4.238798
#> [13,] 4.624277 4.618345
#> [14,] 4.324855 4.847127
#> [15,] 4.291329 4.182920
#> [16,] 4.850867 4.173959
#> GCACTCTAGTTTAGGA-500.1.2 GCAGTTAGTTATGCGT-500.1.2
#> [1,] 4.830855 4.488643
#> [2,] 4.541822 3.963781
#> [3,] 4.257435 4.112953
#> [4,] 4.180297 4.351750
#> [5,] 4.646840 4.979128
#> [6,] 4.612454 4.058318
#> [7,] 4.644981 4.467772
#> [8,] 5.072491 4.484960
#> [9,] 4.553903 4.063843
#> [10,] 4.537175 3.990178
#> [11,] 4.312268 3.998772
#> [12,] 4.386617 4.198895
#> [13,] 4.679368 4.325353
#> [14,] 4.353160 4.135052
#> [15,] 4.182156 4.057704
#> [16,] 4.717472 4.045427
#> GCAGTTATCCCACTTG-500.1.2 GCATGCGGTTCACGGC-500.1.2
#> [1,] 4.559126 4.323699
#> [2,] 4.133676 4.184971
#> [3,] 4.239075 4.563006
#> [4,] 4.250643 4.568786
#> [5,] 4.199229 4.471676
#> [6,] 4.178663 4.424277
#> [7,] 4.317481 4.017341
#> [8,] 5.133676 5.221965
#> [9,] 4.892031 4.587283
#> [10,] 4.638817 4.397688
#> [11,] 4.508997 4.571098
#> [12,] 4.521851 4.409249
#> [13,] 4.475578 4.447399
#> [14,] 4.609254 4.739884
#> [15,] 4.021851 4.286705
#> [16,] 4.652956 4.135260
#> GCGAGAATCCATGAGT-500.1.2 GCGCAACAGACCACGA-500.1.2
#> [1,] 4.630350 4.490391
#> [2,] 3.948444 4.114693
#> [3,] 4.293774 4.375697
#> [4,] 4.254864 4.173590
#> [5,] 4.571012 4.632362
#> [6,] 4.264591 4.681339
#> [7,] 4.270428 4.355239
#> [8,] 4.893969 4.717297
#> [9,] 5.009728 4.631122
#> [10,] 3.945525 4.282703
#> [11,] 4.137160 4.636082
#> [12,] 4.624514 4.443273
#> [13,] 4.963035 4.103534
#> [14,] 4.109922 4.299442
#> [15,] 4.169261 4.386857
#> [16,] 4.772374 4.464972
#> GCGCAGTCACCAGGCT-500.1.2 GCGCCAACAACACCTA-500.1.2
#> [1,] 4.088083 4.233438
#> [2,] 4.335924 4.452681
#> [3,] 4.320380 4.413249
#> [4,] 4.444732 4.467666
#> [5,] 4.765112 4.227918
#> [6,] 4.310881 4.373817
#> [7,] 4.050086 4.227918
#> [8,] 4.868739 4.743691
#> [9,] 4.661485 4.768139
#> [10,] 4.119171 4.672713
#> [11,] 4.430915 4.372240
#> [12,] 4.620898 4.141167
#> [13,] 4.589810 4.414038
#> [14,] 4.032815 4.397476
#> [15,] 4.094991 4.518927
#> [16,] 4.824698 4.211356
#> GCGGGTTAGTCCATAC-500.1.2 GCGGGTTCACAGGCCT-500.1.2
#> [1,] 4.472826 4.568627
#> [2,] 4.074728 4.252723
#> [3,] 4.043478 4.075163
#> [4,] 3.947011 4.053377
#> [5,] 4.533967 4.629630
#> [6,] 4.358696 4.257081
#> [7,] 4.517663 4.007625
#> [8,] 4.839674 5.031590
#> [9,] 5.205163 4.652505
#> [10,] 4.456522 4.236383
#> [11,] 3.959239 4.185185
#> [12,] 4.588315 4.437908
#> [13,] 4.543478 5.230937
#> [14,] 4.247283 4.330065
#> [15,] 4.529891 4.086057
#> [16,] 4.463315 4.572985
#> GCGGGTTGTTCTCATT-500.1.2 GCTGCAGTCAAGCCTA-500.1.2
#> [1,] 4.557355 4.399843
#> [2,] 4.213225 4.236449
#> [3,] 3.974359 4.604870
#> [4,] 4.134953 4.435192
#> [5,] 4.338731 4.632364
#> [6,] 4.499325 4.440691
#> [7,] 4.356275 4.118617
#> [8,] 4.709852 4.970935
#> [9,] 4.678812 4.564808
#> [10,] 4.148448 4.504321
#> [11,] 4.168691 4.241948
#> [12,] 4.669366 4.526316
#> [13,] 4.489879 4.502749
#> [14,] 4.313090 4.294580
#> [15,] 4.417004 4.290652
#> [16,] 4.963563 4.436764
#> GCTTGAACACCGATAT-500.1.2 GGAATAAAGAACAACT-500.1.2
#> [1,] 4.652240 4.487050
#> [2,] 4.324981 4.669615
#> [3,] 4.117692 4.342388
#> [4,] 4.222475 4.310171
#> [5,] 4.666667 4.593178
#> [6,] 4.324222 4.232470
#> [7,] 4.466970 4.473152
#> [8,] 4.797267 4.727732
#> [9,] 4.570235 4.584334
#> [10,] 4.359150 4.761845
#> [11,] 4.398633 4.501579
#> [12,] 4.356112 4.568541
#> [13,] 4.567198 4.516740
#> [14,] 4.425968 4.142767
#> [15,] 4.111617 4.699305
#> [16,] 4.753986 4.531270
#> GGAATAAGTAGCGCTC-500.1.2 GGCAATTAGAACTGTA-500.1.2
#> [1,] 4.510933 4.269076
#> [2,] 4.272000 4.274431
#> [3,] 4.427733 4.485944
#> [4,] 4.197867 4.151272
#> [5,] 4.667733 4.412316
#> [6,] 4.240533 4.167336
#> [7,] 3.998400 4.041499
#> [8,] 5.094933 4.690763
#> [9,] 5.078400 4.374833
#> [10,] 4.374933 4.508701
#> [11,] 4.379733 3.978581
#> [12,] 4.277333 4.465863
#> [13,] 4.676800 4.060241
#> [14,] 4.642667 4.029451
#> [15,] 4.108267 4.187416
#> [16,] 4.658667 4.704150
#> GGCCGATAGGAGTCTG-500.1.2 GGCCGATTCTGGCGTG-500.1.2
#> [1,] 4.244019 5.021448
#> [2,] 4.327751 4.780161
#> [3,] 4.144737 4.280161
#> [4,] 4.192584 4.166220
#> [5,] 4.611244 4.642091
#> [6,] 5.010766 4.403485
#> [7,] 4.114833 4.298928
#> [8,] 4.815789 4.752011
#> [9,] 4.186603 4.991957
#> [10,] 4.391148 4.193029
#> [11,] 4.278708 4.317694
#> [12,] 4.228469 4.682306
#> [13,] 4.276316 4.761394
#> [14,] 4.784689 4.274799
#> [15,] 4.106459 4.250670
#> [16,] 4.861244 4.781501
#> GGCTCGACACAAGACG-500.1.2 GGGAATGGTAGGGTAC-500.1.2
#> [1,] 4.628154 4.280000
#> [2,] 4.342629 4.308387
#> [3,] 4.458167 4.190968
#> [4,] 4.217795 4.356129
#> [5,] 4.548473 4.643871
#> [6,] 4.471448 4.040000
#> [7,] 4.095618 4.224516
#> [8,] 5.183267 4.847742
#> [9,] 4.524568 4.330323
#> [10,] 4.588313 4.383226
#> [11,] 4.600266 4.169032
#> [12,] 4.855246 4.318710
#> [13,] 4.450199 4.531613
#> [14,] 4.790173 4.175484
#> [15,] 4.418327 4.309677
#> [16,] 4.475432 4.215484
#> GGGACCTCACACGCTG-500.1.2 GGGCACTGTCTCATCC-500.1.2
#> [1,] 4.829582 4.294007
#> [2,] 4.341908 4.116105
#> [3,] 4.112540 4.802434
#> [4,] 4.296892 4.542135
#> [5,] 4.617363 4.576779
#> [6,] 4.353698 4.537453
#> [7,] 4.140407 4.720037
#> [8,] 5.379421 5.177903
#> [9,] 4.678457 4.538390
#> [10,] 3.962487 4.086142
#> [11,] 4.139335 4.477528
#> [12,] 4.234727 4.490637
#> [13,] 5.245445 3.761236
#> [14,] 4.175777 4.532772
#> [15,] 3.842444 4.467228
#> [16,] 4.197213 4.170412
#> GGTATTGGTTGTCTTT-500.1.2 GGTGAAGGTCATGCCG-500.1.2
#> [1,] 4.574349 4.343722
#> [2,] 4.324349 4.294746
#> [3,] 4.036245 4.500445
#> [4,] 4.288104 4.460374
#> [5,] 4.213755 4.435441
#> [6,] 4.237918 4.230632
#> [7,] 4.326208 4.082814
#> [8,] 4.854089 4.956367
#> [9,] 4.776952 4.757792
#> [10,] 4.160781 4.254675
#> [11,] 4.532528 4.232413
#> [12,] 4.391264 4.242208
#> [13,] 4.941450 4.456812
#> [14,] 4.095725 4.560107
#> [15,] 4.261152 4.301870
#> [16,] 4.365242 4.463936
#> GGTGTTAAGGCCCGTT-500.1.2 GTAACGTAGCCTATGT-500.1.2
#> [1,] 4.654252 4.903139
#> [2,] 4.650528 4.465471
#> [3,] 4.142148 4.060090
#> [4,] 4.505276 4.147085
#> [5,] 4.590317 4.626906
#> [6,] 4.312228 4.330942
#> [7,] 4.494724 4.269955
#> [8,] 4.648045 4.430493
#> [9,] 4.497827 4.565919
#> [10,] 4.569832 4.406278
#> [11,] 4.214773 4.191031
#> [12,] 4.749845 4.274439
#> [13,] 4.592800 4.391928
#> [14,] 4.296710 4.194619
#> [15,] 4.379888 4.337220
#> [16,] 4.397269 4.787444
#> GTACGTAAGGGATGGG-500.1.2 GTAGGCCCATGTAAGA-500.1.2
#> [1,] 4.585557 4.659784
#> [2,] 4.005495 4.404130
#> [3,] 4.240973 4.300885
#> [4,] 4.179749 3.959685
#> [5,] 4.310047 4.679449
#> [6,] 4.724490 4.302852
#> [7,] 3.919937 4.305801
#> [8,] 4.808477 5.081613
#> [9,] 4.584772 4.740413
#> [10,] 4.251962 4.310718
#> [11,] 3.996075 4.527040
#> [12,] 4.349294 4.261554
#> [13,] 4.799058 4.692232
#> [14,] 4.460754 4.342183
#> [15,] 4.143642 4.139626
#> [16,] 4.548666 4.811209
#> GTAGTCAAGTGACATA-500.1.2 GTATTCTTCCAGAGGA-500.1.2
#> [1,] 4.539223 4.384546
#> [2,] 4.192688 4.251572
#> [3,] 4.176695 4.338724
#> [4,] 4.245240 4.418688
#> [5,] 4.722011 4.358491
#> [6,] 4.525514 4.253369
#> [7,] 4.258187 3.942498
#> [8,] 4.912414 4.667565
#> [9,] 4.920792 4.651393
#> [10,] 4.322925 4.369272
#> [11,] 4.233054 4.236298
#> [12,] 4.284844 4.471698
#> [13,] 4.923839 4.400719
#> [14,] 3.813404 4.342318
#> [15,] 4.031988 4.175202
#> [16,] 4.413557 4.465409
#> GTCACAATCGAACGGA-500.1.2 GTCCTCAGTCACAAGG-500.1.2
#> [1,] 4.870929 4.536310
#> [2,] 4.316043 3.917857
#> [3,] 4.147165 4.384524
#> [4,] 4.370326 4.424405
#> [5,] 4.703257 4.709524
#> [6,] 4.318456 4.936310
#> [7,] 3.955368 4.150000
#> [8,] 5.043426 4.723214
#> [9,] 4.873341 4.599405
#> [10,] 4.150784 4.620833
#> [11,] 4.226779 4.608333
#> [12,] 4.689988 4.629167
#> [13,] 4.843185 4.056548
#> [14,] 4.763571 4.503571
#> [15,] 4.013269 4.485119
#> [16,] 4.475271 4.556548
#> GTGCAGCCACTTCTGC-500.1.2 GTGTTAGAGAGGTAGA-500.1.2
#> [1,] 4.539437 4.245466
#> [2,] 4.238732 4.700130
#> [3,] 4.304930 4.349093
#> [4,] 4.485915 4.428756
#> [5,] 4.769718 4.224741
#> [6,] 4.383099 4.000648
#> [7,] 4.075352 3.961140
#> [8,] 5.022535 4.847798
#> [9,] 4.916901 4.988342
#> [10,] 4.143662 4.737694
#> [11,] 4.412676 4.299870
#> [12,] 4.456338 4.134715
#> [13,] 4.707746 4.218912
#> [14,] 4.022535 4.534974
#> [15,] 4.015493 4.692358
#> [16,] 4.350000 4.095855
#> GTTAAGCGTGACGGTA-500.1.2 GTTACAGAGCTAGTGG-500.1.2
#> [1,] 4.648427 4.751152
#> [2,] 4.223666 4.503456
#> [3,] 4.636115 4.233871
#> [4,] 4.719562 4.501152
#> [5,] 4.503420 4.671659
#> [6,] 4.344049 4.453917
#> [7,] 4.153899 4.051843
#> [8,] 4.889193 5.414747
#> [9,] 4.639535 4.593318
#> [10,] 4.237346 4.633641
#> [11,] 4.312585 4.579493
#> [12,] 4.525308 4.255760
#> [13,] 4.672367 5.051843
#> [14,] 4.622435 4.557604
#> [15,] 4.389877 3.814516
#> [16,] 4.393981 4.336406
#> GTTCGGGAGATATACG-500.1.2 TAAACCGAGATGGGTC-500.1.2
#> [1,] 4.386414 4.491667
#> [2,] 4.191537 4.623214
#> [3,] 4.331849 4.000595
#> [4,] 4.418708 4.379167
#> [5,] 4.239421 4.375000
#> [6,] 4.353007 4.248214
#> [7,] 4.320713 4.568452
#> [8,] 4.354120 4.966071
#> [9,] 4.824053 4.482143
#> [10,] 4.148107 4.538095
#> [11,] 4.271715 4.223214
#> [12,] 4.257238 4.905357
#> [13,] 4.512249 4.883333
#> [14,] 4.246102 4.205357
#> [15,] 4.016704 4.511310
#> [16,] 4.554566 4.475595
#> TAAGAGAAGATGGCGT-500.1.2 TAAGAGATCCTCTAGC-500.1.2
#> [1,] 4.503435 4.389360
#> [2,] 4.183513 4.451812
#> [3,] 4.134446 4.498072
#> [4,] 4.243376 4.340015
#> [5,] 4.375859 4.382421
#> [6,] 4.168793 4.589052
#> [7,] 4.323847 4.236700
#> [8,] 4.922473 4.680031
#> [9,] 4.793916 4.608327
#> [10,] 4.103042 4.407864
#> [11,] 4.336605 4.515035
#> [12,] 4.300294 4.315343
#> [13,] 4.789009 4.480339
#> [14,] 4.218842 4.444102
#> [15,] 3.841021 4.247494
#> [16,] 4.836114 4.396299
#> TAAGTGCAGTACGATA-500.1.2 TAAGTGCGTAGATTAG-500.1.2
#> [1,] 4.378199 4.811284
#> [2,] 4.226540 4.183852
#> [3,] 4.280569 4.373541
#> [4,] 4.812322 4.510700
#> [5,] 4.497630 4.388132
#> [6,] 4.479621 4.283074
#> [7,] 3.854028 4.227626
#> [8,] 4.677725 5.021401
#> [9,] 4.836967 4.867704
#> [10,] 4.002844 4.334630
#> [11,] 4.142180 4.398833
#> [12,] 4.449289 4.545720
#> [13,] 4.385782 4.763619
#> [14,] 4.923223 4.482490
#> [15,] 4.028436 4.460117
#> [16,] 4.077725 4.318093
#> TACACGATCTTAGCCC-500.1.2 TACTCATAGTCAAGCG-500.1.2
#> [1,] 4.823049 4.233671
#> [2,] 4.225953 4.513339
#> [3,] 4.115245 4.246550
#> [4,] 4.264065 4.235511
#> [5,] 4.387477 4.583257
#> [6,] 4.676044 4.245630
#> [7,] 4.247731 4.212511
#> [8,] 5.159710 4.612695
#> [9,] 4.597096 4.239190
#> [10,] 4.242287 4.352346
#> [11,] 4.222323 4.488500
#> [12,] 4.448276 4.468261
#> [13,] 4.618875 4.389144
#> [14,] 4.544465 4.193192
#> [15,] 4.166062 4.070837
#> [16,] 4.514519 4.492180
#> TACTTGTTCGCCGTGA-500.1.2 TAGACCAGTCTGGTCG-500.1.2
#> [1,] 4.727347 4.857695
#> [2,] 4.433469 4.061872
#> [3,] 4.510204 4.108275
#> [4,] 4.401633 3.956690
#> [5,] 4.888163 4.616396
#> [6,] 4.337959 4.286930
#> [7,] 4.148571 3.962104
#> [8,] 5.269388 4.846868
#> [9,] 4.879184 4.641145
#> [10,] 4.031020 4.121423
#> [11,] 4.406531 4.135344
#> [12,] 4.472653 4.331013
#> [13,] 4.708571 4.773395
#> [14,] 4.384490 4.038670
#> [15,] 3.992653 4.064965
#> [16,] 4.239184 4.113689
#> TAGGCATGTAAACGCG-500.1.2 TAGTTGGCAGCCAATT-500.1.2
#> [1,] 4.703019 4.226334
#> [2,] 4.398247 4.228916
#> [3,] 4.203505 4.578313
#> [4,] 4.231743 4.257315
#> [5,] 5.038948 4.509466
#> [6,] 4.283350 4.511188
#> [7,] 4.141188 4.246127
#> [8,] 4.736125 4.874355
#> [9,] 4.990263 5.009466
#> [10,] 4.325219 4.363167
#> [11,] 4.295034 4.516351
#> [12,] 4.533593 4.382960
#> [13,] 4.759494 4.631670
#> [14,] 4.570594 4.426850
#> [15,] 4.178189 4.033563
#> [16,] 4.897760 4.702238
#> TATCTCACAAGAGTCG-500.1.2 TATCTCACAAGCTGTT-500.1.2
#> [1,] 4.421421 4.319545
#> [2,] 4.133133 4.411582
#> [3,] 4.353353 4.338676
#> [4,] 4.072072 4.351603
#> [5,] 4.595596 4.338676
#> [6,] 4.251251 4.154085
#> [7,] 4.227227 4.275078
#> [8,] 5.103103 4.949328
#> [9,] 4.378378 4.566701
#> [10,] 4.262262 4.279214
#> [11,] 4.123123 4.383144
#> [12,] 4.364364 4.391417
#> [13,] 4.156156 4.558945
#> [14,] 4.375375 4.321096
#> [15,] 4.270270 4.237849
#> [16,] 4.416416 4.500517
#> TATCTCATCTGCAGTA-500.1.2 TATGCCCAGCATGGCA-500.1.2
#> [1,] 4.386340 4.679330
#> [2,] 4.164118 4.649162
#> [3,] 4.097859 4.443575
#> [4,] 4.573904 4.386592
#> [5,] 4.969419 4.327374
#> [6,] 4.709480 4.262570
#> [7,] 4.294597 3.739665
#> [8,] 4.795107 5.300559
#> [9,] 4.553517 4.668156
#> [10,] 4.777778 4.482682
#> [11,] 4.717635 4.292737
#> [12,] 4.285423 4.139665
#> [13,] 4.161060 4.791061
#> [14,] 4.434251 4.121788
#> [15,] 4.510703 4.117318
#> [16,] 4.499490 4.562011
#> TCAACGAAGCGATATA-500.1.2 TCAATCTAGATGTTAG-500.1.2
#> [1,] 4.668693 4.239884
#> [2,] 4.073708 4.447013
#> [3,] 4.303191 4.169557
#> [4,] 4.231003 4.302505
#> [5,] 4.512158 4.754335
#> [6,] 4.389058 4.145472
#> [7,] 4.126140 4.114644
#> [8,] 4.863222 4.782274
#> [9,] 4.768237 4.578998
#> [10,] 4.411854 4.138728
#> [11,] 4.440729 4.160886
#> [12,] 4.379939 4.452794
#> [13,] 4.531155 4.625241
#> [14,] 4.823708 3.882466
#> [15,] 4.620821 4.046243
#> [16,] 4.543313 4.900771
#> TCAGCAAAGACCTTTG-500.1.2 TCAGCTCTCGCGGATC-500.1.2
#> [1,] 4.645669 4.780320
#> [2,] 4.625422 4.598970
#> [3,] 4.221597 4.441648
#> [4,] 4.632171 4.544622
#> [5,] 4.858268 4.315789
#> [6,] 4.507312 4.036613
#> [7,] 4.164229 4.065217
#> [8,] 4.886389 4.745423
#> [9,] 4.931384 4.891304
#> [10,] 4.397075 5.241419
#> [11,] 4.164229 4.754577
#> [12,] 4.548931 4.229405
#> [13,] 4.881890 4.404462
#> [14,] 4.386952 4.998284
#> [15,] 3.760405 4.888444
#> [16,] 4.173228 3.968535
#> TCAGGATAGCCGATTT-500.1.2 TCATTTGCATTGTGCA-500.1.2
#> [1,] 4.811385 4.411590
#> [2,] 5.029737 4.385587
#> [3,] 3.897196 4.557207
#> [4,] 4.550552 4.794948
#> [5,] 4.288870 4.300892
#> [6,] 5.117247 4.456909
#> [7,] 4.287171 4.196137
#> [8,] 4.759558 5.268945
#> [9,] 4.108751 4.695394
#> [10,] 4.798641 4.361813
#> [11,] 4.248088 4.338782
#> [12,] 4.343246 4.722883
#> [13,] 4.823280 4.625557
#> [14,] 4.435004 4.780832
#> [15,] 4.017842 4.101783
#> [16,] 4.446049 4.300892
#> TCCCGATCATCAGTCA-500.1.2 TCGAGGCGTTCGTCTC-500.1.2
#> [1,] 4.428155 4.367403
#> [2,] 4.218818 4.401473
#> [3,] 4.431802 4.715470
#> [4,] 4.583516 4.575506
#> [5,] 4.304158 4.663904
#> [6,] 4.664478 4.403315
#> [7,] 4.323122 4.302026
#> [8,] 4.919037 4.934622
#> [9,] 4.587163 4.583794
#> [10,] 4.555799 4.368324
#> [11,] 4.362509 4.312155
#> [12,] 4.338439 4.574586
#> [13,] 4.177243 4.423573
#> [14,] 4.485777 4.510129
#> [15,] 4.481400 4.222836
#> [16,] 4.501823 4.385820
#> TCGGTAAAGTGCGTGA-500.1.2 TCGTAGACATTCCTGC-500.1.2
#> [1,] 4.486538 4.585586
#> [2,] 4.536538 4.446446
#> [3,] 4.414744 4.311311
#> [4,] 4.474359 4.396396
#> [5,] 4.444872 4.684685
#> [6,] 4.253846 4.157157
#> [7,] 4.599359 4.023023
#> [8,] 4.933333 4.816817
#> [9,] 4.815385 5.027027
#> [10,] 4.560897 3.991992
#> [11,] 4.483333 4.135135
#> [12,] 4.648718 4.410410
#> [13,] 4.485256 4.372372
#> [14,] 4.369872 4.147147
#> [15,] 4.486538 4.253253
#> [16,] 4.584615 4.625626
#> TGAGCATTCCACGTTC-500.1.2 TGAGGGAAGAATTCCC-500.1.2
#> [1,] 4.710042 4.588188
#> [2,] 4.620934 4.283981
#> [3,] 4.287129 4.320388
#> [4,] 4.287129 4.254854
#> [5,] 4.804809 4.648867
#> [6,] 4.678925 4.397249
#> [7,] 4.371994 4.255663
#> [8,] 4.847242 5.193366
#> [9,] 5.646393 4.966828
#> [10,] 4.141443 4.414239
#> [11,] 4.087694 4.040453
#> [12,] 4.444130 4.467638
#> [13,] 4.711457 4.894822
#> [14,] 4.405941 4.449029
#> [15,] 3.905233 4.139968
#> [16,] 5.026874 4.300162
#> TGAGGGAGTGGTACAG-500.1.2 TGCCCATCAGCGATCC-500.1.2
#> [1,] 4.271861 4.530632
#> [2,] 4.251948 4.264822
#> [3,] 4.074459 4.450593
#> [4,] 4.295238 4.104743
#> [5,] 4.391342 4.260870
#> [6,] 4.520346 4.106719
#> [7,] 4.299567 4.354743
#> [8,] 5.280519 4.505929
#> [9,] 4.700433 4.945652
#> [10,] 4.168831 4.393281
#> [11,] 4.070130 4.183794
#> [12,] 4.419913 4.912055
#> [13,] 4.431169 4.517787
#> [14,] 4.701299 4.139328
#> [15,] 4.400000 4.148221
#> [16,] 4.432900 4.745059
#> TGCGCAGCATACTACG-500.1.2 TGCGCAGGTCTAGTCA-500.1.2
#> [1,] 4.546914 4.252088
#> [2,] 4.062963 4.585073
#> [3,] 4.386420 4.516701
#> [4,] 4.282716 4.177453
#> [5,] 4.587654 4.441545
#> [6,] 4.308642 4.197286
#> [7,] 4.559259 3.970251
#> [8,] 4.801235 5.055846
#> [9,] 4.667901 4.641962
#> [10,] 4.535802 4.069937
#> [11,] 4.541975 4.239562
#> [12,] 4.465432 4.387265
#> [13,] 4.661728 4.456681
#> [14,] 4.138272 4.400313
#> [15,] 4.049383 4.167537
#> [16,] 4.729630 4.585595
#> TGCTACCCACAGACAG-500.1.2 TGGCCAGAGGCTCAGA-500.1.2
#> [1,] 4.404077 4.534290
#> [2,] 4.707434 4.500797
#> [3,] 4.507194 4.599681
#> [4,] 4.207434 4.528708
#> [5,] 4.303357 4.406699
#> [6,] 4.428058 4.049442
#> [7,] 4.226619 4.245614
#> [8,] 4.817746 4.812600
#> [9,] 4.414868 5.199362
#> [10,] 4.299760 4.516746
#> [11,] 4.448441 4.154705
#> [12,] 4.434053 4.484051
#> [13,] 4.135492 4.377990
#> [14,] 4.326139 4.391547
#> [15,] 4.390887 4.230463
#> [16,] 4.474820 4.227273
#> TGGCCAGTCTTCTGGC-500.1.2 TGGCTGGAGATCCGAG-500.1.2
#> [1,] 4.514595 4.780682
#> [2,] 4.395676 4.236364
#> [3,] 4.260541 4.051136
#> [4,] 4.328649 4.122727
#> [5,] 4.661622 4.427273
#> [6,] 4.343784 4.256818
#> [7,] 4.135135 4.121591
#> [8,] 4.847568 5.105682
#> [9,] 5.057297 4.896591
#> [10,] 4.481081 4.263636
#> [11,] 4.288649 3.947727
#> [12,] 4.513514 4.478409
#> [13,] 4.634595 5.050000
#> [14,] 4.140541 4.165909
#> [15,] 4.381622 4.028409
#> [16,] 4.736216 4.593182
#> TGGCTGGAGATGCCAG-500.1.2 TGTATTCAGTATCGAA-500.1.2
#> [1,] 4.586583 4.487822
#> [2,] 4.400936 4.195546
#> [3,] 4.289392 4.410578
#> [4,] 4.379095 4.302714
#> [5,] 4.657566 4.812109
#> [6,] 4.338534 4.381350
#> [7,] 4.286271 4.352122
#> [8,] 5.002340 5.036186
#> [9,] 5.007020 4.866388
#> [10,] 4.268331 4.427279
#> [11,] 4.516381 4.480167
#> [12,] 4.431357 4.473208
#> [13,] 5.093604 4.663187
#> [14,] 4.172387 4.190675
#> [15,] 3.978159 4.084899
#> [16,] 4.464119 4.412665
#> TGTCCCAAGCCGATTT-500.1.2 TTAGGACAGTTGCAGG-500.1.2
#> [1,] 4.313812 4.772093
#> [2,] 4.316022 4.278140
#> [3,] 4.233149 4.298605
#> [4,] 4.125967 4.324651
#> [5,] 4.534807 4.630698
#> [6,] 4.346961 4.400930
#> [7,] 4.228729 4.185116
#> [8,] 5.146961 5.310698
#> [9,] 5.100552 4.548837
#> [10,] 4.340331 4.333023
#> [11,] 4.248619 4.383256
#> [12,] 4.446409 4.368372
#> [13,] 4.870718 4.673488
#> [14,] 4.275138 4.190698
#> [15,] 4.086188 4.106977
#> [16,] 4.449724 4.493953
#> TTCGAAGAGTGTGAAT-500.1.2 TTCGAAGTCTAACTTC-500.1.2
#> [1,] 4.515175 4.457310
#> [2,] 4.480156 4.465497
#> [3,] 4.402335 4.810526
#> [4,] 4.863813 4.445614
#> [5,] 4.517510 4.583626
#> [6,] 4.362646 4.367251
#> [7,] 4.414786 4.265497
#> [8,] 5.006226 4.828070
#> [9,] 4.582879 4.621053
#> [10,] 4.482490 4.290058
#> [11,] 4.456031 4.597661
#> [12,] 4.569650 4.674854
#> [13,] 4.465370 4.135673
#> [14,] 4.217121 4.449123
#> [15,] 4.305837 3.997661
#> [16,] 4.311284 4.474854
#> TTCTCAAAGGCAAAGA-500.1.2 TTCTCAACACAGACAG-500.1.2
#> [1,] 4.229304 4.477768
#> [2,] 4.345598 4.315606
#> [3,] 4.405388 4.362685
#> [4,] 4.399474 4.387969
#> [5,] 4.864652 5.115083
#> [6,] 4.332457 4.143854
#> [7,] 4.363995 3.978204
#> [8,] 4.669514 4.952921
#> [9,] 4.756242 5.093287
#> [10,] 4.335085 4.000000
#> [11,] 4.155716 4.481255
#> [12,] 4.346255 4.205754
#> [13,] 4.607096 4.884045
#> [14,] 4.119580 4.193548
#> [15,] 4.190539 3.967742
#> [16,] 4.683968 4.583261
#> TTGAACGCAGATCGGA-500.1.2 TTGCCGTTCCGAAGAG-500.1.2
#> [1,] 4.714148 4.374570
#> [2,] 4.955727 4.323024
#> [3,] 4.115496 4.676976
#> [4,] 4.556304 4.290951
#> [5,] 4.527430 4.422680
#> [6,] 4.634264 4.450172
#> [7,] 4.284889 3.998855
#> [8,] 4.696824 4.807560
#> [9,] 4.243503 4.285223
#> [10,] 4.958614 4.325315
#> [11,] 4.152069 4.418099
#> [12,] 4.340712 4.477663
#> [13,] 4.736285 4.268041
#> [14,] 4.390760 4.036655
#> [15,] 3.629451 4.510882
#> [16,] 4.417709 4.817869
#> TTGGAACTCCTTCAAT-500.1.2 TTTGGTTAGGTTACCT-500.1.2
#> [1,] 4.378635 4.265193
#> [2,] 4.178971 4.206492
#> [3,] 4.223714 4.260359
#> [4,] 4.508389 4.955801
#> [5,] 4.605705 4.265193
#> [6,] 4.449105 4.513812
#> [7,] 4.581655 4.395028
#> [8,] 4.883110 4.906077
#> [9,] 4.475951 4.795580
#> [10,] 4.469799 4.557320
#> [11,] 4.408837 4.009669
#> [12,] 4.676174 4.483425
#> [13,] 4.194631 4.389503
#> [14,] 3.908277 4.656768
#> [15,] 4.258949 4.438536
#> [16,] 4.345638 4.134669
#> AAACCTGAGCACAGGT-500.1.3 AAAGTAGGTCACTGGC-500.1.3
#> [1,] 4.441070 4.340932
#> [2,] 4.374548 4.507092
#> [3,] 4.327549 4.101824
#> [4,] 4.449747 4.176798
#> [5,] 4.596529 4.393617
#> [6,] 4.686189 4.284195
#> [7,] 4.383948 4.490375
#> [8,] 4.576283 4.869301
#> [9,] 4.205351 4.419959
#> [10,] 4.399132 4.535968
#> [11,] 4.475054 4.359169
#> [12,] 4.506146 4.663627
#> [13,] 4.139552 4.361702
#> [14,] 4.415763 4.121074
#> [15,] 4.237889 4.267984
#> [16,] 4.571945 4.403749
#> AAATGCCCAATGGAAT-500.1.3 AAGACCTTCGAGCCCA-500.1.3
#> [1,] 4.646264 4.508114
#> [2,] 4.166932 4.349899
#> [3,] 4.216216 4.313387
#> [4,] 4.120032 4.527383
#> [5,] 4.525437 4.688641
#> [6,] 4.418124 4.299189
#> [7,] 4.022258 4.268763
#> [8,] 5.182830 4.843813
#> [9,] 4.837043 5.110548
#> [10,] 4.710652 4.277890
#> [11,] 4.243243 4.392495
#> [12,] 4.520668 4.724138
#> [13,] 4.475358 4.792089
#> [14,] 4.394277 4.458418
#> [15,] 4.430843 4.284990
#> [16,] 4.514308 5.062880
#> AGCGTCGGTCCGTCAG-500.1.3 AGCTTGACACAACTGT-500.1.3
#> [1,] 4.105493 4.614894
#> [2,] 4.394071 4.607447
#> [3,] 4.223191 4.192553
#> [4,] 4.729730 4.612766
#> [5,] 4.297297 4.561702
#> [6,] 4.463819 4.153191
#> [7,] 4.135135 4.364894
#> [8,] 5.073235 5.220213
#> [9,] 4.621622 4.893617
#> [10,] 4.060157 4.263830
#> [11,] 4.362685 4.168085
#> [12,] 4.381866 4.420213
#> [13,] 4.515257 4.765957
#> [14,] 5.108108 4.656383
#> [15,] 4.476024 4.236170
#> [16,] 4.251962 4.564894
#> AGCTTGATCAGGCAAG-500.1.3 AGGCCACGTCAAGCGA-500.1.3
#> [1,] 4.274982 4.604938
#> [2,] 4.403260 4.218591
#> [3,] 4.373494 4.258533
#> [4,] 4.795181 4.220044
#> [5,] 4.635011 4.381990
#> [6,] 4.373494 4.310821
#> [7,] 4.386960 4.181554
#> [8,] 4.654146 4.896151
#> [9,] 5.046775 4.962237
#> [10,] 4.536499 4.306463
#> [11,] 4.333806 4.376906
#> [12,] 4.622962 4.459695
#> [13,] 4.184975 4.637618
#> [14,] 4.538625 4.336238
#> [15,] 4.328136 3.935367
#> [16,] 4.225372 4.403776
#> AGGGAGTCAGGTGGAT-500.1.3 ATAACGCCACAGGAGT-500.1.3
#> [1,] 4.387560 4.381125
#> [2,] 4.130981 3.801270
#> [3,] 4.390550 4.154265
#> [4,] 4.128589 4.173321
#> [5,] 4.499402 4.313067
#> [6,] 4.465311 5.126134
#> [7,] 4.367225 3.831216
#> [8,] 4.956938 4.839383
#> [9,] 4.860646 4.570780
#> [10,] 4.534689 4.129764
#> [11,] 4.592703 3.991833
#> [12,] 4.534091 4.331216
#> [13,] 4.217105 4.569873
#> [14,] 4.351675 4.766788
#> [15,] 4.196172 4.090744
#> [16,] 4.578947 4.838475
#> ATCCGAAGTGCGATAG-500.1.3 ATGAGGGTCGACGGAA-500.1.3
#> [1,] 4.153619 4.605578
#> [2,] 4.085672 4.496414
#> [3,] 3.993353 4.544223
#> [4,] 4.109306 4.717131
#> [5,] 4.493353 4.553785
#> [6,] 5.312408 4.512351
#> [7,] 4.149188 4.235857
#> [8,] 5.053914 4.971315
#> [9,] 4.572378 4.876494
#> [10,] 4.547267 4.611155
#> [11,] 4.146233 4.498805
#> [12,] 4.341950 5.054980
#> [13,] 4.457164 4.271713
#> [14,] 5.034712 4.345817
#> [15,] 3.930576 4.325896
#> [16,] 5.006647 4.344223
#> ATTGGTGTCATGGTCA-500.1.3 CAAGATCAGCCACCTG-500.1.3
#> [1,] 3.996743 4.326174
#> [2,] 4.302932 4.204027
#> [3,] 4.745928 4.461745
#> [4,] 4.484256 4.430872
#> [5,] 4.396308 4.198658
#> [6,] 4.138979 3.897987
#> [7,] 4.371336 3.822819
#> [8,] 4.899023 4.845638
#> [9,] 4.856678 4.879195
#> [10,] 4.439739 4.524832
#> [11,] 4.414767 4.110067
#> [12,] 4.875136 4.706040
#> [13,] 4.310532 4.328859
#> [14,] 4.325733 4.715436
#> [15,] 4.270358 4.668456
#> [16,] 4.375679 4.065772
#> CACATTTCACGCCAGT-500.1.3 CACATTTTCATGCATG-500.1.3
#> [1,] 4.429040 4.896455
#> [2,] 4.008431 4.763993
#> [3,] 4.379859 3.956157
#> [4,] 4.299766 4.545709
#> [5,] 4.659016 4.391791
#> [6,] 4.985948 4.482276
#> [7,] 4.451522 4.324627
#> [8,] 4.706792 5.027985
#> [9,] 4.599532 4.161381
#> [10,] 4.533021 4.741604
#> [11,] 4.696019 4.447761
#> [12,] 4.309133 4.434701
#> [13,] 3.967213 4.958022
#> [14,] 4.568150 4.203358
#> [15,] 4.221546 4.098881
#> [16,] 4.381265 4.189366
#> CAGAATCAGTTTAGGA-500.1.3 CAGAATCCAGACTCGC-500.1.3
#> [1,] 4.453618 4.679389
#> [2,] 3.980519 4.309706
#> [3,] 4.181818 4.184297
#> [4,] 3.886827 4.174482
#> [5,] 4.130798 4.196292
#> [6,] 4.190167 4.276990
#> [7,] 4.494434 4.515812
#> [8,] 4.613173 4.884406
#> [9,] 4.619666 4.546347
#> [10,] 4.213358 4.210469
#> [11,] 4.496289 4.069793
#> [12,] 4.701299 4.386041
#> [13,] 4.341373 4.651036
#> [14,] 4.152134 4.267176
#> [15,] 4.308905 4.403490
#> [16,] 4.723562 4.472192
#> CCACTACGTCGGCACT-500.1.3 CCGGTAGCATGCGCAC-500.1.3
#> [1,] 4.031250 4.283747
#> [2,] 4.714527 4.086318
#> [3,] 4.231419 4.360882
#> [4,] 4.344595 4.176309
#> [5,] 3.879223 4.149679
#> [6,] 4.318412 4.634527
#> [7,] 4.141047 4.004591
#> [8,] 4.917230 4.606061
#> [9,] 5.365709 4.846648
#> [10,] 4.894426 4.206612
#> [11,] 4.301520 4.254362
#> [12,] 4.094595 4.415978
#> [13,] 4.381757 4.581267
#> [14,] 4.571791 4.413223
#> [15,] 4.981419 3.860422
#> [16,] 4.264358 4.608815
#> CGACTTCGTTGTGGAG-500.1.3 CGATGGCTCTGTTGAG-500.1.3
#> [1,] 4.196931 4.097622
#> [2,] 4.167945 4.272215
#> [3,] 4.504689 4.537547
#> [4,] 4.244672 4.075720
#> [5,] 4.436488 4.333542
#> [6,] 4.514919 4.095119
#> [7,] 4.417732 4.523154
#> [8,] 5.184996 4.637046
#> [9,] 4.872123 4.669587
#> [10,] 4.328218 4.539424
#> [11,] 4.531117 4.354193
#> [12,] 4.427962 4.912390
#> [13,] 4.174766 4.408010
#> [14,] 4.397272 4.188986
#> [15,] 4.119352 4.439925
#> [16,] 4.659847 4.518148
#> CGCCAAGCAATGAATG-500.1.3 CGGACACGTGCAGGTA-500.1.3
#> [1,] 4.232288 4.517191
#> [2,] 4.089431 4.468178
#> [3,] 4.117305 4.346745
#> [4,] 3.940767 4.337235
#> [5,] 4.250871 4.221653
#> [6,] 4.353078 4.411851
#> [7,] 4.090592 4.147037
#> [8,] 4.714286 4.936357
#> [9,] 4.443670 4.730797
#> [10,] 4.238095 4.658376
#> [11,] 3.963995 4.163862
#> [12,] 4.433217 4.784931
#> [13,] 4.457607 4.197513
#> [14,] 4.166086 4.577908
#> [15,] 4.257840 4.623263
#> [16,] 4.896632 4.448427
#> CGGACGTTCAGTCAGT-500.1.3 CGGAGCTCATCTATGG-500.1.3
#> [1,] 4.319714 4.284180
#> [2,] 4.197140 4.164551
#> [3,] 4.640960 4.426758
#> [4,] 4.159346 4.295410
#> [5,] 4.760981 4.843262
#> [6,] 4.922370 5.038574
#> [7,] 4.153218 4.187988
#> [8,] 5.004086 5.089844
#> [9,] 4.732891 4.765137
#> [10,] 4.717058 4.516602
#> [11,] 4.936670 4.687988
#> [12,] 4.490807 4.323242
#> [13,] 4.324311 4.283203
#> [14,] 4.639939 4.831543
#> [15,] 4.353933 4.477539
#> [16,] 4.551073 4.389160
#> CGGCTAGCATGCGCAC-500.1.3 CGTTGGGAGTGGGCTA-500.1.3
#> [1,] 4.353969 4.263259
#> [2,] 4.258558 4.541853
#> [3,] 4.424618 4.508626
#> [4,] 4.456664 4.290735
#> [5,] 4.667152 4.558466
#> [6,] 4.295703 4.346326
#> [7,] 4.176256 4.198722
#> [8,] 5.205390 4.875399
#> [9,] 4.981792 4.913738
#> [10,] 4.312454 4.336102
#> [11,] 4.310269 4.314377
#> [12,] 4.496723 4.271565
#> [13,] 4.781500 4.360383
#> [14,] 4.442826 4.394888
#> [15,] 3.970867 4.259425
#> [16,] 4.140568 4.781470
#> CGTTGGGTCGACGGAA-500.1.3 CTACATTAGGAGCGAG-500.1.3
#> [1,] 4.238136 4.568627
#> [2,] 4.236411 4.591597
#> [3,] 4.242450 4.200000
#> [4,] 4.804142 4.540056
#> [5,] 4.295945 4.378151
#> [6,] 4.196721 4.077311
#> [7,] 4.057808 4.270028
#> [8,] 4.855910 4.961905
#> [9,] 5.003451 4.970308
#> [10,] 4.432269 4.522689
#> [11,] 4.008628 4.295238
#> [12,] 4.420190 4.673389
#> [13,] 4.433995 4.529412
#> [14,] 4.962899 4.618487
#> [15,] 4.248490 4.475630
#> [16,] 4.155306 4.560784
#> CTAGTGAAGAGGGCTT-500.1.3 CTCGAAAAGGTTACCT-500.1.3
#> [1,] 4.528074 4.299793
#> [2,] 4.269367 4.213174
#> [3,] 3.936745 4.363589
#> [4,] 4.247335 3.837656
#> [5,] 4.246624 4.382780
#> [6,] 4.592751 4.179461
#> [7,] 4.269367 4.344917
#> [8,] 4.976546 4.925830
#> [9,] 4.696517 4.532676
#> [10,] 4.341862 4.320021
#> [11,] 4.103056 4.132261
#> [12,] 4.512438 4.549793
#> [13,] 4.395167 4.517116
#> [14,] 4.406539 4.082469
#> [15,] 4.098081 4.730290
#> [16,] 4.867804 4.432573
#> CTCGAGGGTGAAATCA-500.1.3 CTGATCCAGCTCCTTC-500.1.3
#> [1,] 4.299031 4.817100
#> [2,] 4.376917 4.620130
#> [3,] 4.337772 3.751082
#> [4,] 4.272801 4.202381
#> [5,] 4.549233 4.666667
#> [6,] 4.416465 4.279221
#> [7,] 3.791768 4.058442
#> [8,] 5.381356 5.360390
#> [9,] 5.238499 5.112554
#> [10,] 4.600081 3.843074
#> [11,] 4.386602 3.975108
#> [12,] 4.398709 4.125541
#> [13,] 4.482244 5.244589
#> [14,] 4.472559 4.337662
#> [15,] 4.129540 3.735931
#> [16,] 4.502421 4.465368
#> CTTACCGGTACATGTC-500.1.3 GAAATGAGTCCAAGTT-500.1.3
#> [1,] 4.384071 4.678380
#> [2,] 4.474336 4.368984
#> [3,] 4.124779 4.288006
#> [4,] 4.505310 4.353705
#> [5,] 4.401770 4.330787
#> [6,] 4.391150 4.623377
#> [7,] 4.338053 4.298701
#> [8,] 5.113274 5.079450
#> [9,] 4.613274 4.747899
#> [10,] 4.735398 4.346830
#> [11,] 4.169027 4.407945
#> [12,] 4.319469 4.569901
#> [13,] 4.638938 4.741788
#> [14,] 4.774336 4.488159
#> [15,] 4.068142 4.104660
#> [16,] 4.599115 4.339954
#> GAAATGAGTTACCGAT-500.1.3 GACAGAGAGGCATGGT-500.1.3
#> [1,] 3.982625 4.500000
#> [2,] 4.430502 4.493233
#> [3,] 4.439189 4.238346
#> [4,] 4.379344 4.272932
#> [5,] 4.258687 4.824060
#> [6,] 4.249035 4.317293
#> [7,] 3.921815 4.131579
#> [8,] 4.916988 4.831579
#> [9,] 4.883205 4.875188
#> [10,] 4.241313 4.164662
#> [11,] 4.411197 4.247368
#> [12,] 4.205598 4.410526
#> [13,] 4.366795 4.863910
#> [14,] 4.257722 3.888722
#> [15,] 4.635135 3.936842
#> [16,] 4.965251 4.569925
#> GACGTTACACGGCCAT-500.1.3 GATCGTATCGCTAGCG-500.1.3
#> [1,] 4.613117 4.320531
#> [2,] 4.016212 4.607542
#> [3,] 4.311717 4.511872
#> [4,] 4.462049 4.469972
#> [5,] 4.882093 4.417598
#> [6,] 4.593220 4.384078
#> [7,] 3.893884 4.321229
#> [8,] 4.965365 4.779330
#> [9,] 4.741341 4.756285
#> [10,] 4.222550 4.392458
#> [11,] 4.098747 4.348464
#> [12,] 4.498895 4.474860
#> [13,] 5.023581 4.389665
#> [14,] 4.213707 4.386872
#> [15,] 3.950626 4.230447
#> [16,] 4.361828 4.592877
#> GCACATAGTTAAAGTG-500.1.3 GCAGCCAGTTGGTTTG-500.1.3
#> [1,] 4.498433 4.453450
#> [2,] 4.141066 4.301205
#> [3,] 4.460031 3.936473
#> [4,] 4.906740 4.518072
#> [5,] 4.654389 4.457831
#> [6,] 4.400470 4.469880
#> [7,] 4.576019 4.426068
#> [8,] 5.063480 4.723987
#> [9,] 4.419279 5.106243
#> [10,] 4.604232 4.004381
#> [11,] 4.371473 4.324206
#> [12,] 4.744514 4.479737
#> [13,] 4.134013 4.414020
#> [14,] 4.597962 4.152245
#> [15,] 4.463950 4.360350
#> [16,] 4.128527 4.832421
#> GCATACATCTGTTGAG-500.1.3 GCTCCTAGTTTGACAC-500.1.3
#> [1,] 4.294664 3.972327
#> [2,] 4.109049 4.451572
#> [3,] 4.153906 4.330818
#> [4,] 4.262181 4.396226
#> [5,] 4.695282 4.817610
#> [6,] 4.201083 4.314465
#> [7,] 3.993039 4.177358
#> [8,] 4.960557 4.826415
#> [9,] 4.530549 4.402516
#> [10,] 4.058778 4.623899
#> [11,] 4.150039 4.105660
#> [12,] 4.316319 4.563522
#> [13,] 4.372003 4.075472
#> [14,] 4.185615 4.140881
#> [15,] 4.095128 4.332075
#> [16,] 4.549111 4.700629
#> GCTTCCAGTGTGCCTG-500.1.3 GGCAATTAGTTGTAGA-500.1.3
#> [1,] 4.566976 4.592456
#> [2,] 4.390059 4.292548
#> [3,] 4.075821 4.228151
#> [4,] 4.201348 4.559338
#> [5,] 4.381634 4.528979
#> [6,] 4.540859 4.318307
#> [7,] 4.024431 4.441582
#> [8,] 4.987363 4.698252
#> [9,] 4.617523 4.939282
#> [10,] 3.976411 4.321067
#> [11,] 4.099410 4.427783
#> [12,] 4.470093 4.656854
#> [13,] 4.737995 4.493100
#> [14,] 4.264532 4.174793
#> [15,] 4.229992 4.094756
#> [16,] 4.650379 4.826127
#> GGCGACTGTTGCTCCT-500.1.3 GGGAATGTCTGATTCT-500.1.3
#> [1,] 4.285714 4.520000
#> [2,] 4.330952 4.597838
#> [3,] 4.132143 3.922162
#> [4,] 3.958333 4.646486
#> [5,] 4.357143 4.788108
#> [6,] 4.322619 4.543784
#> [7,] 3.811905 4.091892
#> [8,] 4.716667 4.875676
#> [9,] 4.459524 4.951351
#> [10,] 4.372619 4.416216
#> [11,] 4.069048 4.435676
#> [12,] 4.892857 4.440000
#> [13,] 4.452381 4.361081
#> [14,] 4.177381 4.761081
#> [15,] 4.345238 4.531892
#> [16,] 4.815476 4.379459
#> GTAACTGAGACCTAGG-500.1.3 GTACTTTTCGAGGTAG-500.1.3
#> [1,] 4.713008 4.216581
#> [2,] 3.912195 4.449871
#> [3,] 3.953659 4.652314
#> [4,] 4.202439 4.264139
#> [5,] 4.669919 4.271851
#> [6,] 4.276423 4.035990
#> [7,] 4.094309 4.478149
#> [8,] 4.993496 5.100900
#> [9,] 4.684553 4.521208
#> [10,] 4.108943 4.357969
#> [11,] 4.328455 4.746144
#> [12,] 4.548780 4.397815
#> [13,] 4.714634 4.077121
#> [14,] 4.220325 4.311054
#> [15,] 4.091057 4.350900
#> [16,] 4.495935 4.539203
#> GTAGGCCAGCACCGTC-500.1.3 GTAGTCATCGAATGCT-500.1.3
#> [1,] 4.487050 4.312867
#> [2,] 4.288489 4.169824
#> [3,] 3.953957 4.438929
#> [4,] 4.447482 4.182234
#> [5,] 4.246043 4.446767
#> [6,] 4.682014 4.452645
#> [7,] 4.438129 4.408883
#> [8,] 4.854676 4.721750
#> [9,] 4.485612 4.336381
#> [10,] 4.674101 4.357936
#> [11,] 4.435971 4.388635
#> [12,] 4.494964 4.513390
#> [13,] 4.373381 4.007185
#> [14,] 4.364748 4.001960
#> [15,] 4.209353 4.401045
#> [16,] 4.323022 4.506858
#> GTCATTTCATGCCTTC-500.1.3 GTTAAGCCAACTTGAC-500.1.3
#> [1,] 4.377217 4.212450
#> [2,] 4.604514 4.757282
#> [3,] 4.314884 4.158195
#> [4,] 4.307899 4.437464
#> [5,] 4.220312 4.439178
#> [6,] 4.276733 4.202170
#> [7,] 4.622246 4.434609
#> [8,] 4.874798 5.034266
#> [9,] 4.672219 4.531125
#> [10,] 4.523912 4.812107
#> [11,] 4.225148 4.259852
#> [12,] 4.633530 4.548829
#> [13,] 4.204191 4.462022
#> [14,] 4.344976 4.445460
#> [15,] 4.405159 4.532267
#> [16,] 4.477163 4.519703
#> TAAACCGGTACCATCA-500.1.3 TAAGCGTTCCTTTCTC-500.1.3
#> [1,] 4.123196 4.608290
#> [2,] 3.979381 4.673575
#> [3,] 4.613918 4.439378
#> [4,] 4.270103 4.920207
#> [5,] 4.592784 4.276684
#> [6,] 4.438660 4.692228
#> [7,] 4.094330 4.271503
#> [8,] 5.050515 5.288083
#> [9,] 4.852577 4.539896
#> [10,] 4.316495 4.000000
#> [11,] 4.545876 4.650777
#> [12,] 4.444330 4.461140
#> [13,] 4.359794 4.120207
#> [14,] 4.350515 4.355440
#> [15,] 4.209278 4.321244
#> [16,] 4.599485 4.292228
#> TACAGTGTCGAATGCT-500.1.3 TACTCGCGTATTCTCT-500.1.3
#> [1,] 4.378185 4.342319
#> [2,] 4.511943 4.627670
#> [3,] 4.366242 4.386572
#> [4,] 4.515127 4.501526
#> [5,] 4.312102 4.339776
#> [6,] 4.224522 4.624619
#> [7,] 4.199841 4.351475
#> [8,] 5.140924 4.814852
#> [9,] 5.078822 4.851984
#> [10,] 4.225318 4.489318
#> [11,] 4.414809 4.384028
#> [12,] 4.305732 4.638861
#> [13,] 4.459395 4.343337
#> [14,] 4.394108 4.534588
#> [15,] 4.084395 4.346897
#> [16,] 4.476115 4.755849
#> TACTTGTAGCGGATCA-500.1.3 TAGACCAAGAAACGCC-500.1.3
#> [1,] 4.049618 4.942041
#> [2,] 4.376590 4.284898
#> [3,] 4.416031 4.283265
#> [4,] 4.161578 4.599184
#> [5,] 4.323155 4.316735
#> [6,] 3.994911 4.537959
#> [7,] 4.231552 4.171429
#> [8,] 5.059796 5.218776
#> [9,] 4.997455 4.765714
#> [10,] 4.455471 4.353469
#> [11,] 4.240458 4.133061
#> [12,] 4.614504 4.103673
#> [13,] 4.061069 4.455510
#> [14,] 4.435115 4.385306
#> [15,] 3.702290 4.256327
#> [16,] 4.729008 4.596735
#> TAGGCATCAACGCACC-500.1.3 TAGGCATCATGATCCA-500.1.3
#> [1,] 4.358873 4.766852
#> [2,] 4.356056 4.597938
#> [3,] 4.232676 3.693894
#> [4,] 4.295211 4.201427
#> [5,] 4.614085 4.091990
#> [6,] 4.512113 4.420301
#> [7,] 4.461972 4.206979
#> [8,] 4.548732 4.887391
#> [9,] 4.482817 4.164155
#> [10,] 4.296338 4.991277
#> [11,] 4.482254 4.258525
#> [12,] 4.402254 4.260111
#> [13,] 4.249577 4.626487
#> [14,] 4.370704 4.259318
#> [15,] 4.106479 3.857256
#> [16,] 4.315493 4.443299
#> TAGTTGGAGACTTGAA-500.1.3 TAGTTGGCACCGAATT-500.1.3
#> [1,] 4.421922 4.575788
#> [2,] 4.136637 4.439471
#> [3,] 4.205706 4.264496
#> [4,] 4.417417 4.775178
#> [5,] 4.202703 4.977620
#> [6,] 4.409910 4.151577
#> [7,] 4.120871 4.097660
#> [8,] 5.442943 5.257375
#> [9,] 4.704955 5.165819
#> [10,] 4.230480 4.259410
#> [11,] 4.280781 4.442523
#> [12,] 4.461712 4.272635
#> [13,] 4.563063 4.759919
#> [14,] 4.660661 4.625636
#> [15,] 4.298048 3.889115
#> [16,] 4.319820 4.188199
#> TCAGGATTCACTCTTA-500.1.3 TCCACACGTGTGACGA-500.1.3
#> [1,] 4.494711 4.578868
#> [2,] 4.295362 4.261132
#> [3,] 4.366151 4.120000
#> [4,] 4.518308 4.387170
#> [5,] 4.607811 4.624151
#> [6,] 4.979658 4.281509
#> [7,] 4.172498 4.195472
#> [8,] 4.936534 5.083774
#> [9,] 4.458910 4.968302
#> [10,] 4.403580 4.519245
#> [11,] 4.222945 4.464906
#> [12,] 4.478438 4.264906
#> [13,] 4.264443 4.523774
#> [14,] 4.537022 4.727547
#> [15,] 4.497152 4.306415
#> [16,] 4.221318 4.535094
#> TCTGGAAGTCGAAAGC-500.1.3 TCTTTCCTCAGTTTGG-500.1.3
#> [1,] 4.460733 4.521177
#> [2,] 4.193717 4.367552
#> [3,] 4.350785 4.111989
#> [4,] 4.314136 4.043790
#> [5,] 4.123411 4.542714
#> [6,] 4.218399 4.407035
#> [7,] 4.462977 4.159368
#> [8,] 4.741960 5.103374
#> [9,] 4.724009 4.761665
#> [10,] 4.433807 4.597990
#> [11,] 4.327599 4.257717
#> [12,] 4.414361 4.584350
#> [13,] 4.402393 4.395549
#> [14,] 4.198205 4.867193
#> [15,] 4.307405 4.573582
#> [16,] 4.341810 4.559943
#> TGCGGGTAGGATGGTC-500.1.3 TGCGTGGTCGCCAAAT-500.1.3
#> [1,] 4.106685 4.086928
#> [2,] 4.418636 4.195090
#> [3,] 4.592843 4.177173
#> [4,] 4.282242 4.221632
#> [5,] 4.641458 4.536828
#> [6,] 4.151924 4.149303
#> [7,] 3.891290 3.988719
#> [8,] 5.026334 5.356337
#> [9,] 5.023633 5.013271
#> [10,] 4.328832 4.104844
#> [11,] 4.385550 4.323159
#> [12,] 4.497637 4.135368
#> [13,] 4.442269 4.666888
#> [14,] 4.080351 4.564698
#> [15,] 4.292370 4.070338
#> [16,] 4.696151 4.652953
#> TGCTACCAGCGGATCA-500.1.3 TGGCCAGCAAGTACCT-500.1.3
#> [1,] 4.120287 4.430657
#> [2,] 4.230700 4.334307
#> [3,] 3.938061 4.690511
#> [4,] 4.043986 4.333577
#> [5,] 4.191203 4.221898
#> [6,] 3.990126 4.520438
#> [7,] 4.294434 4.150365
#> [8,] 4.589767 5.167883
#> [9,] 4.591562 5.013139
#> [10,] 4.392280 4.230657
#> [11,] 4.164273 4.269343
#> [12,] 4.802513 4.528467
#> [13,] 4.276481 4.140876
#> [14,] 4.146320 4.600000
#> [15,] 4.486535 4.063504
#> [16,] 5.084381 4.595620
#> TGTATTCGTAAAGGAG-500.1.3 TTAGGCAAGTCGAGTG-500.1.3
#> [1,] 4.298515 4.651323
#> [2,] 3.915515 3.771958
#> [3,] 4.537634 3.744444
#> [4,] 4.358935 4.447619
#> [5,] 4.635945 5.053968
#> [6,] 4.803891 3.886772
#> [7,] 4.377368 4.730688
#> [8,] 4.724526 4.269312
#> [9,] 4.737327 4.235979
#> [10,] 4.710701 3.808995
#> [11,] 4.865335 3.856085
#> [12,] 4.497184 4.065608
#> [13,] 3.907322 4.536508
#> [14,] 4.624680 4.495767
#> [15,] 4.438812 3.830159
#> [16,] 4.400922 4.135450
#> TTCCCAGGTCGGCACT-500.1.3 TTCTACACATGGAATA-500.1.3
#> [1,] 4.500316 4.214286
#> [2,] 4.589387 4.310847
#> [3,] 4.035376 3.818783
#> [4,] 4.349968 3.769841
#> [5,] 4.159823 4.369048
#> [6,] 4.615919 4.272487
#> [7,] 4.166140 4.328042
#> [8,] 4.828806 4.677249
#> [9,] 4.840177 4.367725
#> [10,] 4.583702 4.231481
#> [11,] 4.303222 3.986772
#> [12,] 4.458623 4.448413
#> [13,] 4.300695 4.764550
#> [14,] 4.437776 3.857143
#> [15,] 4.370815 4.087302
#> [16,] 4.454833 4.710317
#> TTTATGCTCACTATTC-500.1.3 TTTGTCAAGGGTTCCC-500.1.3
#> [1,] 4.391547 4.339566
#> [2,] 4.230463 4.306657
#> [3,] 4.217703 4.593867
#> [4,] 4.202552 4.599102
#> [5,] 4.120415 4.279731
#> [6,] 4.248006 4.403889
#> [7,] 4.196172 4.243829
#> [8,] 5.290271 5.056844
#> [9,] 4.936204 4.885565
#> [10,] 4.240829 4.275991
#> [11,] 4.114035 4.201945
#> [12,] 4.203349 4.507853
#> [13,] 4.617225 4.457741
#> [14,] 4.500000 4.719521
#> [15,] 3.962520 4.178758
#> [16,] 4.478469 4.417352
#> AAACGGGTCGAATGGG-500.2.1 AAAGCAAGTTCAGTAC-500.2.1
#> [1,] 4.130695 4.538366
#> [2,] 4.069544 4.283416
#> [3,] 4.496403 4.575495
#> [4,] 4.121103 4.152228
#> [5,] 4.540767 4.766089
#> [6,] 4.803357 4.233911
#> [7,] 4.394484 4.289604
#> [8,] 4.889688 4.726485
#> [9,] 4.773381 4.347772
#> [10,] 4.522782 4.282178
#> [11,] 4.687050 4.304455
#> [12,] 4.486811 4.021040
#> [13,] 4.017986 4.236386
#> [14,] 4.488010 4.188119
#> [15,] 4.069544 4.407178
#> [16,] 4.586331 4.267327
#> AAAGTAGTCAGGCAAG-500.2.1 AAATGCCTCACAACGT-500.2.1
#> [1,] 4.434667 4.302698
#> [2,] 4.304000 4.105396
#> [3,] 4.429333 4.284992
#> [4,] 4.232000 4.418212
#> [5,] 4.524000 4.566610
#> [6,] 4.245333 4.384486
#> [7,] 4.369333 4.352445
#> [8,] 4.714667 5.157673
#> [9,] 4.508000 4.543845
#> [10,] 4.578667 4.466273
#> [11,] 4.384000 4.852445
#> [12,] 4.693333 4.701518
#> [13,] 4.657333 4.046374
#> [14,] 4.177333 4.488196
#> [15,] 4.198667 4.111298
#> [16,] 4.320000 4.363406
#> AACACGTGTGCGGTAA-500.2.1 AACCGCGTCTATCGCC-500.2.1
#> [1,] 4.407883 4.205411
#> [2,] 4.338222 4.461924
#> [3,] 4.546288 4.671343
#> [4,] 4.257562 4.095190
#> [5,] 4.455545 4.277555
#> [6,] 3.959670 4.397796
#> [7,] 4.232814 4.151303
#> [8,] 5.167736 4.735471
#> [9,] 4.858845 4.734469
#> [10,] 4.108158 4.538076
#> [11,] 4.491292 4.095190
#> [12,] 4.395967 4.481964
#> [13,] 4.289643 4.572144
#> [14,] 4.449129 4.269539
#> [15,] 4.153071 4.388778
#> [16,] 4.541705 4.170341
#> AACTCAGAGATCACGG-500.2.1 AACTCTTCAGCCTTTC-500.2.1
#> [1,] 4.736318 4.394495
#> [2,] 4.097844 4.210092
#> [3,] 4.308458 4.203670
#> [4,] 4.283582 4.199083
#> [5,] 4.809287 4.286239
#> [6,] 4.723881 4.137615
#> [7,] 4.092869 4.228440
#> [8,] 4.833333 4.849541
#> [9,] 4.377280 4.788073
#> [10,] 4.372305 4.395413
#> [11,] 4.685738 4.316514
#> [12,] 4.557214 4.504587
#> [13,] 3.970978 4.211927
#> [14,] 4.830017 4.333945
#> [15,] 4.317579 4.712844
#> [16,] 4.325041 4.593578
#> AACTCTTGTTGGACCC-500.2.1 AAGCCGCCAACTGCTA-500.2.1
#> [1,] 4.541383 4.665327
#> [2,] 4.046738 4.394975
#> [3,] 4.759494 4.504523
#> [4,] 4.224927 4.563819
#> [5,] 4.617332 4.243216
#> [6,] 4.848101 4.363819
#> [7,] 4.199611 3.893467
#> [8,] 4.793574 4.780905
#> [9,] 4.935735 4.849246
#> [10,] 4.542356 4.504523
#> [11,] 4.872444 4.246231
#> [12,] 4.618306 4.414070
#> [13,] 4.044791 4.553769
#> [14,] 4.754625 4.605025
#> [15,] 4.317429 4.173869
#> [16,] 4.443038 4.497487
#> AAGCCGCCATGTTGAC-500.2.1 AATCGGTCAAACGTGG-500.2.1
#> [1,] 4.361564 4.621771
#> [2,] 4.616721 4.422509
#> [3,] 4.432139 4.495387
#> [4,] 4.362649 4.876384
#> [5,] 4.053203 4.632841
#> [6,] 4.127036 4.520295
#> [7,] 4.306189 4.127306
#> [8,] 4.825190 4.896679
#> [9,] 4.847991 4.544280
#> [10,] 4.859935 4.676199
#> [11,] 4.106406 4.174354
#> [12,] 4.209555 4.348708
#> [13,] 4.396308 4.283210
#> [14,] 4.625407 4.309963
#> [15,] 4.778502 4.427122
#> [16,] 4.328990 4.398524
#> ACACCAAAGTCTTGCA-500.2.1 ACACCAAGTAGCGATG-500.2.1
#> [1,] 4.438250 4.512285
#> [2,] 4.189132 4.374693
#> [3,] 4.215949 4.733415
#> [4,] 4.165843 4.507371
#> [5,] 4.601270 4.409091
#> [6,] 4.482004 4.638821
#> [7,] 4.081157 4.321867
#> [8,] 4.712068 4.783784
#> [9,] 4.804517 4.776413
#> [10,] 4.440367 4.450860
#> [11,] 4.320395 4.143735
#> [12,] 4.486239 4.584767
#> [13,] 4.236415 4.530713
#> [14,] 4.702188 3.920147
#> [15,] 4.316867 4.169533
#> [16,] 4.510233 4.054054
#> ACACTGAAGGAATGGA-500.2.1 ACAGCCGGTATTCGTG-500.2.1
#> [1,] 4.632156 4.323056
#> [2,] 5.175396 4.777480
#> [3,] 4.526188 4.434316
#> [4,] 4.261876 4.412869
#> [5,] 4.046285 4.450402
#> [6,] 4.906212 4.136729
#> [7,] 3.863581 4.138070
#> [8,] 4.113276 4.934316
#> [9,] 4.252132 4.841823
#> [10,] 4.149817 4.357909
#> [11,] 4.772229 4.128686
#> [12,] 5.057247 4.344504
#> [13,] 4.347138 4.420912
#> [14,] 3.900122 4.630027
#> [15,] 4.006090 4.242627
#> [16,] 4.032887 4.282842
#> ACAGCTAAGTTAGCGG-500.2.1 ACAGCTACACAGAGGT-500.2.1
#> [1,] 4.394265 4.324000
#> [2,] 4.258065 4.716000
#> [3,] 4.581541 4.448000
#> [4,] 4.620072 4.305333
#> [5,] 4.420251 4.557333
#> [6,] 3.977599 4.145333
#> [7,] 4.112007 3.966667
#> [8,] 4.507168 5.030667
#> [9,] 4.810932 4.780000
#> [10,] 4.509857 4.097333
#> [11,] 4.382616 4.486667
#> [12,] 4.775090 4.425333
#> [13,] 4.272401 4.596000
#> [14,] 4.398746 4.410667
#> [15,] 4.241039 4.060000
#> [16,] 4.033154 4.566667
#> ACAGCTACACCACCAG-500.2.1 ACATACGTCAACACGT-500.2.1
#> [1,] 4.395489 4.252075
#> [2,] 4.157895 4.424274
#> [3,] 4.425564 4.606846
#> [4,] 4.140602 4.553942
#> [5,] 4.233083 4.563278
#> [6,] 4.868421 4.306017
#> [7,] 4.223308 4.516598
#> [8,] 4.655639 4.580913
#> [9,] 4.639850 4.585062
#> [10,] 4.155639 4.581950
#> [11,] 4.169173 4.456432
#> [12,] 4.228571 4.591286
#> [13,] 4.064662 4.621369
#> [14,] 4.744361 4.345436
#> [15,] 4.244361 4.463693
#> [16,] 4.649624 4.251037
#> ACATCAGAGAAGGTTT-500.2.1 ACATCAGTCCTTAATC-500.2.1
#> [1,] 4.226286 4.457490
#> [2,] 4.277714 4.493575
#> [3,] 4.385143 4.312621
#> [4,] 4.400000 4.455730
#> [5,] 4.141714 4.420877
#> [6,] 4.329143 4.459778
#> [7,] 3.922286 4.076571
#> [8,] 5.080000 4.954057
#> [9,] 4.597714 4.560993
#> [10,] 4.412571 4.428974
#> [11,] 4.299429 4.460834
#> [12,] 4.397714 4.405210
#> [13,] 3.816000 4.265798
#> [14,] 4.009143 4.575251
#> [15,] 4.421714 4.395001
#> [16,] 4.312000 4.421405
#> ACATGGTCAAAGCGGT-500.2.1 ACCAGTACAGTTAACC-500.2.1
#> [1,] 4.291937 4.522310
#> [2,] 4.244671 4.245407
#> [3,] 4.439296 4.709974
#> [4,] 4.341057 4.396325
#> [5,] 4.444856 4.460630
#> [6,] 4.078777 4.324147
#> [7,] 4.073216 4.326772
#> [8,] 4.780352 4.948819
#> [9,] 4.949027 4.629921
#> [10,] 4.312326 4.405512
#> [11,] 4.430955 4.101050
#> [12,] 4.358665 4.665354
#> [13,] 4.701576 4.448819
#> [14,] 4.339203 4.325459
#> [15,] 4.189064 4.598425
#> [16,] 4.412419 4.219160
#> ACCGTAATCTGGTATG-500.2.1 ACGATGTAGCTATGCT-500.2.1
#> [1,] 4.606494 4.382406
#> [2,] 4.350649 4.342011
#> [3,] 4.770130 4.322262
#> [4,] 4.445455 4.195691
#> [5,] 5.185714 4.074506
#> [6,] 4.135065 4.337522
#> [7,] 4.149351 4.162478
#> [8,] 5.115584 4.745961
#> [9,] 4.424675 5.008079
#> [10,] 4.183117 4.695691
#> [11,] 4.651948 4.359066
#> [12,] 4.446753 4.459605
#> [13,] 4.027273 4.504488
#> [14,] 4.049351 4.158887
#> [15,] 4.272727 4.510772
#> [16,] 4.451948 4.074506
#> ACGCAGCTCATTTGGG-500.2.1 ACGCAGCTCCTGCCAT-500.2.1
#> [1,] 4.304833 4.435146
#> [2,] 4.480793 4.096234
#> [3,] 4.671623 4.276151
#> [4,] 4.133829 4.994770
#> [5,] 4.530359 4.673640
#> [6,] 4.189591 4.142259
#> [7,] 4.179678 3.962343
#> [8,] 4.724907 5.402720
#> [9,] 4.597274 5.352510
#> [10,] 4.381660 4.624477
#> [11,] 4.573730 4.303347
#> [12,] 4.289963 3.822176
#> [13,] 4.399009 3.867155
#> [14,] 4.224287 4.690377
#> [15,] 4.437423 4.109833
#> [16,] 4.280050 4.422594
#> ACGGCCAGTATTAGCC-500.2.1 ACGGGCTCAATCAGAA-500.2.1
#> [1,] 4.549628 4.354635
#> [2,] 4.233871 4.315032
#> [3,] 4.202854 4.539154
#> [4,] 4.464020 4.729073
#> [5,] 4.578784 4.481548
#> [6,] 4.401365 4.027003
#> [7,] 4.220844 4.162016
#> [8,] 4.974566 4.748875
#> [9,] 4.277916 4.888389
#> [10,] 4.268610 4.353735
#> [11,] 4.201613 4.379838
#> [12,] 4.361042 4.360036
#> [13,] 4.442928 4.284428
#> [14,] 4.503722 4.454545
#> [15,] 3.978908 4.117012
#> [16,] 4.115385 4.221422
#> ACGGGCTGTCTAGTCA-500.2.1 ACGGGCTTCAGCTCGG-500.2.1
#> [1,] 4.323498 4.239161
#> [2,] 4.198103 4.604196
#> [3,] 4.516333 4.721678
#> [4,] 4.260274 4.581818
#> [5,] 4.632244 4.406993
#> [6,] 4.582719 4.316084
#> [7,] 4.004215 4.269930
#> [8,] 5.082192 5.043357
#> [9,] 5.073762 4.678322
#> [10,] 4.681770 4.532867
#> [11,] 4.576396 4.469930
#> [12,] 4.444679 4.841958
#> [13,] 4.041096 4.703497
#> [14,] 4.146470 4.402797
#> [15,] 4.095890 4.309091
#> [16,] 4.498419 4.212587
#> ACGGGTCCAGAGCCAA-500.2.1 ACTATCTAGCTCCTCT-500.2.1
#> [1,] 4.277330 4.446436
#> [2,] 4.617952 4.382158
#> [3,] 4.485616 4.324503
#> [4,] 4.310702 4.423451
#> [5,] 4.466053 4.294118
#> [6,] 4.346375 4.435917
#> [7,] 3.859609 4.182704
#> [8,] 4.827388 4.814959
#> [9,] 4.434983 4.856252
#> [10,] 4.117376 4.474484
#> [11,] 4.616801 4.249708
#> [12,] 4.607595 4.488508
#> [13,] 4.322209 4.407480
#> [14,] 4.696203 4.269186
#> [15,] 4.157652 4.344371
#> [16,] 4.322209 4.470588
#> ACTATCTCACAGCCCA-500.2.1 ACTGAACGTCCGTGAC-500.2.1
#> [1,] 4.495238 4.292784
#> [2,] 4.369312 4.775258
#> [3,] 4.571429 4.552577
#> [4,] 4.230688 4.441237
#> [5,] 4.593651 4.303093
#> [6,] 4.271958 3.947423
#> [7,] 3.962963 4.022680
#> [8,] 4.879365 4.683505
#> [9,] 4.771429 4.964948
#> [10,] 4.283598 4.575258
#> [11,] 4.258201 4.330928
#> [12,] 4.440212 4.472165
#> [13,] 4.578836 4.448454
#> [14,] 4.478307 4.497938
#> [15,] 4.200000 4.876289
#> [16,] 4.656085 4.115464
#> ACTGATGGTCTCACCT-500.2.1 ACTGTCCGTGCAGGTA-500.2.1
#> [1,] 4.335509 4.254069
#> [2,] 4.553525 4.171790
#> [3,] 4.627937 4.173599
#> [4,] 4.601828 4.549729
#> [5,] 4.570496 4.660036
#> [6,] 4.398172 4.583183
#> [7,] 4.048303 4.245931
#> [8,] 4.630548 4.956600
#> [9,] 4.578329 4.500904
#> [10,] 4.519582 4.701627
#> [11,] 4.375979 4.643761
#> [12,] 4.242820 4.278481
#> [13,] 4.237598 4.166365
#> [14,] 4.113577 4.392405
#> [15,] 4.477807 4.239602
#> [16,] 4.352480 4.361664
#> ACTTACTAGGGTCTCC-500.2.1 ACTTACTGTTCACCTC-500.2.1
#> [1,] 4.327247 4.625265
#> [2,] 5.301966 4.233546
#> [3,] 4.671348 4.215499
#> [4,] 4.429775 4.364119
#> [5,] 4.310393 4.627389
#> [6,] 4.745787 4.333333
#> [7,] 3.967697 4.036093
#> [8,] 4.339888 4.613588
#> [9,] 3.724719 4.713376
#> [10,] 4.323034 4.266454
#> [11,] 4.587079 4.199575
#> [12,] 4.831461 4.612527
#> [13,] 3.998596 4.421444
#> [14,] 3.897472 4.464968
#> [15,] 3.969101 4.176221
#> [16,] 4.183989 4.278132
#> ACTTACTTCTGCCAGG-500.2.1 ACTTGTTTCTTGTCAT-500.2.1
#> [1,] 4.528590 4.325843
#> [2,] 4.263024 4.608614
#> [3,] 4.325286 4.690075
#> [4,] 4.189327 4.268727
#> [5,] 4.650572 4.661985
#> [6,] 4.364676 3.890449
#> [7,] 4.128335 4.381086
#> [8,] 4.363405 4.508427
#> [9,] 4.546379 4.182584
#> [10,] 4.312579 4.287453
#> [11,] 4.388818 4.492509
#> [12,] 4.452351 4.314607
#> [13,] 4.428208 4.331461
#> [14,] 4.273189 4.488764
#> [15,] 4.005083 4.347378
#> [16,] 4.434562 4.730337
#> AGACGTTTCGCCCTTA-500.2.1 AGAGCGATCAGGCAAG-500.2.1
#> [1,] 5.006257 4.747002
#> [2,] 5.288843 4.184652
#> [3,] 4.409802 4.171463
#> [4,] 4.149114 4.406475
#> [5,] 4.193952 4.278177
#> [6,] 4.779979 3.902878
#> [7,] 3.997914 4.214628
#> [8,] 4.374348 4.850120
#> [9,] 3.802920 4.942446
#> [10,] 4.364964 4.345324
#> [11,] 4.607925 4.290168
#> [12,] 4.852972 4.503597
#> [13,] 4.111575 4.594724
#> [14,] 4.130344 4.374101
#> [15,] 3.864442 4.003597
#> [16,] 4.089677 4.456835
#> AGAGCTTTCACAGTAC-500.2.1 AGAGTGGAGGTGCAAC-500.2.1
#> [1,] 4.323963 4.352234
#> [2,] 4.306560 4.396048
#> [3,] 4.926372 4.682990
#> [4,] 4.107095 4.298110
#> [5,] 4.708166 4.465636
#> [6,] 4.057564 4.399485
#> [7,] 3.961178 4.205326
#> [8,] 4.872825 4.867698
#> [9,] 4.382865 4.652062
#> [10,] 4.228916 4.246564
#> [11,] 4.235609 4.376289
#> [12,] 4.421687 4.805842
#> [13,] 4.389558 4.487113
#> [14,] 4.044177 4.175258
#> [15,] 4.223561 4.144330
#> [16,] 4.431058 4.490550
#> AGAGTGGGTCCTAGCG-500.2.1 AGATCTGAGTCTTGCA-500.2.1
#> [1,] 4.549101 4.369311
#> [2,] 4.708160 4.418726
#> [3,] 4.319502 4.421326
#> [4,] 4.329184 4.159948
#> [5,] 4.067773 4.416125
#> [6,] 4.441217 4.501951
#> [7,] 3.849239 4.265280
#> [8,] 4.744122 4.863459
#> [9,] 4.508990 4.345904
#> [10,] 4.929461 4.282185
#> [11,] 4.022130 4.240572
#> [12,] 4.746888 4.540962
#> [13,] 4.573997 4.616385
#> [14,] 4.336100 4.488947
#> [15,] 4.132780 4.377113
#> [16,] 4.055325 4.154746
#> AGATCTGCACTCTGTC-500.2.1 AGATTGCCATCCGGGT-500.2.1
#> [1,] 4.350685 4.090483
#> [2,] 4.075342 4.307641
#> [3,] 4.626027 4.743298
#> [4,] 4.342466 4.173592
#> [5,] 4.587671 4.745308
#> [6,] 4.294521 4.321046
#> [7,] 4.382192 4.038874
#> [8,] 4.930137 5.216488
#> [9,] 4.573973 4.395442
#> [10,] 4.460274 4.555630
#> [11,] 4.584932 4.361930
#> [12,] 4.726027 4.540214
#> [13,] 4.043836 4.428284
#> [14,] 4.158904 4.269437
#> [15,] 4.328767 4.479893
#> [16,] 4.323288 4.373324
#> AGCATACGTAAACGCG-500.2.1 AGCGGTCGTAAACCTC-500.2.1
#> [1,] 4.419683 4.679775
#> [2,] 4.248869 4.650562
#> [3,] 4.332579 4.357303
#> [4,] 4.640271 4.757303
#> [5,] 4.657240 4.365169
#> [6,] 4.021493 4.419101
#> [7,] 4.392534 4.337079
#> [8,] 4.688914 5.126966
#> [9,] 4.650452 4.753933
#> [10,] 4.053167 4.015730
#> [11,] 4.435520 4.550562
#> [12,] 4.615385 4.480899
#> [13,] 4.371041 4.286517
#> [14,] 4.210407 4.210112
#> [15,] 4.690045 4.159551
#> [16,] 4.338235 4.248315
#> AGCTCCTAGAGGTAGA-500.2.1 AGCTCCTCAGGGTATG-500.2.1
#> [1,] 3.930993 4.492456
#> [2,] 4.330508 4.301750
#> [3,] 4.371671 4.594448
#> [4,] 4.503632 4.179843
#> [5,] 4.380145 4.452022
#> [6,] 4.000000 4.277610
#> [7,] 4.429782 4.097767
#> [8,] 4.576271 4.990042
#> [9,] 4.559322 4.892275
#> [10,] 4.243341 4.296922
#> [11,] 4.282082 4.278817
#> [12,] 4.418886 4.356065
#> [13,] 4.544794 4.514786
#> [14,] 4.492736 4.216958
#> [15,] 4.679177 4.166264
#> [16,] 4.285714 4.499698
#> AGCTTGACAGCTATTG-500.2.1 AGGCCGTAGTTACCCA-500.2.1
#> [1,] 4.437618 4.668966
#> [2,] 4.613422 4.243678
#> [3,] 4.557656 4.470115
#> [4,] 4.417769 4.459770
#> [5,] 4.777883 4.362069
#> [6,] 4.541588 4.217241
#> [7,] 4.264650 4.357471
#> [8,] 5.128544 4.820690
#> [9,] 4.868620 4.805747
#> [10,] 4.762760 4.513793
#> [11,] 4.714556 4.339080
#> [12,] 4.534026 4.370115
#> [13,] 4.534026 4.474713
#> [14,] 4.303403 4.294253
#> [15,] 4.365784 4.037931
#> [16,] 4.321361 4.367816
#> AGGGAGTGTTCCGTCT-500.2.1 AGGTCATGTCTCCACT-500.2.1
#> [1,] 4.638536 4.488910
#> [2,] 4.439881 4.634523
#> [3,] 4.474981 4.501446
#> [4,] 4.389843 4.336548
#> [5,] 4.712472 4.467695
#> [6,] 4.295743 4.337512
#> [7,] 4.156833 4.269045
#> [8,] 4.964899 4.701061
#> [9,] 4.569081 4.572806
#> [10,] 4.579537 4.397300
#> [11,] 4.351008 4.316297
#> [12,] 4.294996 4.148505
#> [13,] 4.375653 4.351013
#> [14,] 4.283047 4.453230
#> [15,] 4.071695 4.247830
#> [16,] 4.227782 4.419479
#> AGTGAGGGTTACCGAT-500.2.1 AGTGGGAAGATATGCA-500.2.1
#> [1,] 4.602394 4.537004
#> [2,] 4.046543 4.153430
#> [3,] 4.216755 4.416065
#> [4,] 4.454787 4.444946
#> [5,] 4.639628 4.476534
#> [6,] 4.441489 4.537004
#> [7,] 4.031915 4.059567
#> [8,] 4.880319 4.886282
#> [9,] 4.710106 4.624549
#> [10,] 4.263298 4.364621
#> [11,] 4.340426 4.600181
#> [12,] 4.492021 4.825812
#> [13,] 4.319149 4.011733
#> [14,] 4.680851 4.597473
#> [15,] 4.305851 4.543321
#> [16,] 4.236702 4.157040
#> AGTGGGAGTAAACACA-500.2.1 AGTTGGTAGCTCAACT-500.2.1
#> [1,] 4.428994 4.404564
#> [2,] 4.334320 4.401452
#> [3,] 4.303254 4.593361
#> [4,] 4.174556 4.042531
#> [5,] 4.692308 4.358921
#> [6,] 4.464497 4.169087
#> [7,] 4.545858 4.164938
#> [8,] 5.042899 5.047718
#> [9,] 4.470414 4.559129
#> [10,] 4.164201 4.258299
#> [11,] 4.105030 4.303942
#> [12,] 4.319527 4.477178
#> [13,] 4.587278 4.532158
#> [14,] 4.344675 4.221992
#> [15,] 4.430473 4.101660
#> [16,] 4.332840 4.355809
#> AGTTGGTCAAACAACA-500.2.1 ATAACGCAGCTATGCT-500.2.1
#> [1,] 4.471545 4.314360
#> [2,] 4.611498 4.166882
#> [3,] 4.316492 4.503234
#> [4,] 4.364692 4.187581
#> [5,] 4.445993 4.485123
#> [6,] 4.188734 4.309185
#> [7,] 4.123693 4.112549
#> [8,] 4.954704 4.827943
#> [9,] 4.778165 4.557568
#> [10,] 4.548200 4.419146
#> [11,] 4.307782 4.829237
#> [12,] 4.409988 4.306598
#> [13,] 4.345528 4.446313
#> [14,] 4.634727 4.389392
#> [15,] 4.433217 4.517464
#> [16,] 4.193380 4.244502
#> ATAGACCCACATGTGT-500.2.1 ATCACGATCTTAGCCC-500.2.1
#> [1,] 4.112011 4.731429
#> [2,] 4.709852 4.337143
#> [3,] 4.252362 4.536327
#> [4,] 4.263158 4.284898
#> [5,] 4.464238 4.440816
#> [6,] 4.454791 4.057959
#> [7,] 4.298246 4.000816
#> [8,] 4.676113 4.804898
#> [9,] 4.616734 4.293878
#> [10,] 4.700405 3.880816
#> [11,] 4.429150 4.013878
#> [12,] 4.167341 4.313469
#> [13,] 4.379217 4.600816
#> [14,] 4.232119 3.957551
#> [15,] 4.363023 4.145306
#> [16,] 4.228070 4.496327
#> ATGGGAGAGCCTTGAT-500.2.1 ATGGGAGCACAGAGGT-500.2.1
#> [1,] 4.189071 4.416781
#> [2,] 3.867760 4.554333
#> [3,] 4.518033 4.499312
#> [4,] 4.156284 4.193948
#> [5,] 4.028415 4.536451
#> [6,] 4.772678 4.229711
#> [7,] 4.194536 4.215956
#> [8,] 4.809836 4.672627
#> [9,] 4.280874 4.489684
#> [10,] 4.369399 4.141678
#> [11,] 3.901639 4.221458
#> [12,] 4.296175 4.928473
#> [13,] 4.288525 4.517194
#> [14,] 4.554098 4.319120
#> [15,] 4.251366 4.708391
#> [16,] 4.723497 4.429161
#> ATGGGAGTCAACACTG-500.2.1 ATGTGTGAGCGACGTA-500.2.1
#> [1,] 4.494631 4.530208
#> [2,] 4.666782 4.390625
#> [3,] 4.637686 4.492708
#> [4,] 4.418081 4.320833
#> [5,] 4.250087 4.381250
#> [6,] 4.431590 4.540625
#> [7,] 4.241773 3.881250
#> [8,] 4.784551 5.014583
#> [9,] 4.445791 4.736458
#> [10,] 4.487703 4.145833
#> [11,] 4.625216 3.963542
#> [12,] 4.660547 4.486458
#> [13,] 4.171805 4.352083
#> [14,] 4.146172 4.657292
#> [15,] 4.470384 4.202083
#> [16,] 4.165223 4.394792
#> ATTACTCCACTCGACG-500.2.1 ATTACTCGTTCTGTTT-500.2.1
#> [1,] 4.741176 4.784135
#> [2,] 3.925792 4.552666
#> [3,] 4.685068 4.527958
#> [4,] 4.205430 4.355007
#> [5,] 4.710407 4.283485
#> [6,] 4.551131 4.465540
#> [7,] 4.036199 4.022107
#> [8,] 4.679638 4.869961
#> [9,] 4.604525 4.361508
#> [10,] 4.423529 4.465540
#> [11,] 4.585520 4.331599
#> [12,] 4.215385 4.397919
#> [13,] 4.120362 4.479844
#> [14,] 4.628959 4.087126
#> [15,] 4.228959 4.117035
#> [16,] 4.685973 4.282185
#> ATTACTCTCTCGAGTA-500.2.1 ATTGGTGGTGTGTGCC-500.2.1
#> [1,] 4.917235 4.500973
#> [2,] 4.256086 3.842412
#> [3,] 4.103213 4.559339
#> [4,] 4.010711 4.008755
#> [5,] 4.749757 4.633268
#> [6,] 4.034080 4.774319
#> [7,] 3.716650 4.315175
#> [8,] 4.896787 4.756809
#> [9,] 4.260954 4.780156
#> [10,] 4.103213 4.228599
#> [11,] 4.275560 4.474708
#> [12,] 4.175268 4.399805
#> [13,] 4.532619 3.927043
#> [14,] 4.336904 4.545720
#> [15,] 3.967868 4.130350
#> [16,] 4.317429 4.262646
#> ATTGGTGTCCTGCCAT-500.2.1 ATTGGTGTCTTTACAC-500.2.1
#> [1,] 4.226804 4.459610
#> [2,] 4.055412 4.265181
#> [3,] 4.557990 4.522563
#> [4,] 4.367268 4.431755
#> [5,] 4.530928 4.757103
#> [6,] 4.476804 4.028412
#> [7,] 4.101804 4.732591
#> [8,] 4.958763 4.514763
#> [9,] 4.783505 4.554875
#> [10,] 4.219072 4.264067
#> [11,] 3.853093 4.274095
#> [12,] 4.203608 4.171031
#> [13,] 4.534794 4.477437
#> [14,] 4.867268 4.412813
#> [15,] 4.039948 3.776045
#> [16,] 4.360825 4.160446
#> CAACCAATCGAACTGT-500.2.1 CAACCTCAGACCACGA-500.2.1
#> [1,] 4.343852 4.219477
#> [2,] 4.291621 4.628634
#> [3,] 4.577802 4.380087
#> [4,] 4.767138 4.102471
#> [5,] 4.223069 4.298692
#> [6,] 4.377584 3.957122
#> [7,] 4.154516 4.108285
#> [8,] 4.635473 4.855378
#> [9,] 5.088139 4.404797
#> [10,] 4.383025 4.500727
#> [11,] 4.435256 4.446948
#> [12,] 4.485310 4.513808
#> [13,] 4.635473 4.401890
#> [14,] 4.321001 4.784157
#> [15,] 3.966268 3.827035
#> [16,] 4.313384 4.280523
#> CAACCTCTCGTCCGTT-500.2.1 CAAGATCCATTCTTAC-500.2.1
#> [1,] 4.343990 4.557292
#> [2,] 4.262148 4.091146
#> [3,] 4.598465 4.438802
#> [4,] 4.670077 4.087240
#> [5,] 4.452685 4.688802
#> [6,] 4.038363 3.951823
#> [7,] 4.248082 4.130208
#> [8,] 4.768542 4.703125
#> [9,] 4.855499 4.673177
#> [10,] 4.152174 4.218750
#> [11,] 4.327366 4.501302
#> [12,] 4.728900 4.218750
#> [13,] 4.466752 4.516927
#> [14,] 4.461637 4.058594
#> [15,] 3.998721 3.975260
#> [16,] 4.292839 4.522135
#> CAAGTTGTCAGTTTGG-500.2.1 CACAAACTCACATACG-500.2.1
#> [1,] 4.655904 4.212804
#> [2,] 4.410517 4.151488
#> [3,] 4.321033 4.403066
#> [4,] 4.524908 4.575293
#> [5,] 4.490775 4.511271
#> [6,] 4.167897 3.990983
#> [7,] 4.078413 4.401262
#> [8,] 5.015683 4.636610
#> [9,] 4.392066 4.815149
#> [10,] 4.304428 4.621280
#> [11,] 4.414207 4.502254
#> [12,] 4.547970 4.379621
#> [13,] 4.325646 4.242561
#> [14,] 4.499077 4.523895
#> [15,] 4.219557 4.596934
#> [16,] 4.354244 4.234445
#> CACACAAGTAGGAGTC-500.2.1 CACACCTCAATCGAAA-500.2.1
#> [1,] 4.579781 4.510353
#> [2,] 4.051157 4.253350
#> [3,] 4.950061 4.651644
#> [4,] 4.115713 4.900122
#> [5,] 4.371498 4.437272
#> [6,] 4.333739 4.422655
#> [7,] 4.411693 4.012180
#> [8,] 5.164434 5.390987
#> [9,] 4.814860 3.963459
#> [10,] 4.159562 4.202192
#> [11,] 4.176614 4.531060
#> [12,] 4.633374 4.527406
#> [13,] 4.142509 4.550548
#> [14,] 4.455542 4.193666
#> [15,] 4.255786 4.395859
#> [16,] 4.264312 3.963459
#> CACAGGCGTCGAGATG-500.2.1 CACATAGCATCAGTCA-500.2.1
#> [1,] 4.120853 4.354588
#> [2,] 4.501185 4.083204
#> [3,] 4.554502 4.388025
#> [4,] 4.777251 4.513997
#> [5,] 4.444313 4.748056
#> [6,] 4.492891 4.671073
#> [7,] 4.278436 4.108087
#> [8,] 4.501185 4.987558
#> [9,] 4.751185 4.502333
#> [10,] 4.329384 4.444012
#> [11,] 4.356635 4.631415
#> [12,] 4.427725 4.367030
#> [13,] 4.680095 4.020218
#> [14,] 4.475118 4.435459
#> [15,] 4.466825 4.212286
#> [16,] 3.971564 4.659409
#> CACATTTAGTCACGCC-500.2.1 CACATTTCAGCCAGAA-500.2.1
#> [1,] 4.384342 4.597811
#> [2,] 4.232028 4.369357
#> [3,] 4.615658 4.722298
#> [4,] 4.387900 4.272230
#> [5,] 4.608541 4.683995
#> [6,] 4.644840 4.102599
#> [7,] 4.049110 4.047880
#> [8,] 5.148754 4.621067
#> [9,] 4.740214 4.626539
#> [10,] 4.604270 4.689466
#> [11,] 4.837722 4.348837
#> [12,] 4.752313 4.804378
#> [13,] 4.244840 4.629275
#> [14,] 4.485409 4.132695
#> [15,] 4.200712 4.086183
#> [16,] 4.390036 4.607387
#> CACCACTCAAACGTGG-500.2.1 CACCTTGCAAGCCATT-500.2.1
#> [1,] 4.018182 4.444706
#> [2,] 4.298347 5.029412
#> [3,] 4.488430 4.501176
#> [4,] 4.265289 4.347059
#> [5,] 4.384298 4.428235
#> [6,] 4.272727 4.669412
#> [7,] 4.070248 4.402353
#> [8,] 4.654545 4.588235
#> [9,] 4.515702 4.097647
#> [10,] 4.353719 4.657647
#> [11,] 4.362810 4.581176
#> [12,] 4.571074 4.870588
#> [13,] 4.456198 4.580000
#> [14,] 4.211570 4.417647
#> [15,] 4.477686 3.825882
#> [16,] 4.383471 4.183529
#> CAGAATCAGAAACCAT-500.2.1 CAGAATCAGATCCCAT-500.2.1
#> [1,] 4.036166 4.572405
#> [2,] 4.278481 4.417029
#> [3,] 4.655515 4.345556
#> [4,] 4.328210 5.129273
#> [5,] 4.265823 4.108763
#> [6,] 4.367993 4.183344
#> [7,] 4.021700 3.949037
#> [8,] 4.735986 4.919826
#> [9,] 4.828210 4.446861
#> [10,] 4.266727 4.646986
#> [11,] 4.453888 4.351150
#> [12,] 4.546112 4.349285
#> [13,] 4.307414 4.356743
#> [14,] 4.447559 4.338098
#> [15,] 4.066004 4.441889
#> [16,] 4.379747 4.336855
#> CAGAATCAGATCCTGT-500.2.1 CAGATCACATCGATGT-500.2.1
#> [1,] 4.201128 4.511682
#> [2,] 4.472744 4.246495
#> [3,] 4.340226 4.646028
#> [4,] 4.487782 4.198598
#> [5,] 4.265038 4.502336
#> [6,] 3.924812 4.448598
#> [7,] 4.174812 4.184579
#> [8,] 4.552632 5.113318
#> [9,] 5.284774 4.565421
#> [10,] 5.125000 4.512850
#> [11,] 4.310150 4.581776
#> [12,] 4.196429 4.428738
#> [13,] 4.136278 4.389019
#> [14,] 4.255639 4.253505
#> [15,] 4.866541 4.521028
#> [16,] 4.067669 4.484813
#> CAGCAGCAGCACCGTC-500.2.1 CAGCAGCCATTCCTGC-500.2.1
#> [1,] 4.456633 4.572443
#> [2,] 4.380952 4.399148
#> [3,] 4.480867 4.666193
#> [4,] 4.334184 4.265625
#> [5,] 4.386480 4.410511
#> [6,] 4.481718 4.485795
#> [7,] 4.063350 4.292614
#> [8,] 4.853741 5.062500
#> [9,] 4.801020 4.762784
#> [10,] 4.260204 4.342330
#> [11,] 4.289541 4.732955
#> [12,] 4.384779 4.612216
#> [13,] 4.352891 4.940341
#> [14,] 4.520833 4.376420
#> [15,] 4.161139 4.204545
#> [16,] 4.520408 4.610795
#> CAGCATAAGTGAAGAG-500.2.1 CAGCATAGTAGCGTGA-500.2.1
#> [1,] 4.201789 5.020487
#> [2,] 4.107881 5.605634
#> [3,] 4.360537 4.700384
#> [4,] 4.589715 4.060179
#> [5,] 4.439911 4.129321
#> [6,] 4.590274 4.828425
#> [7,] 3.988262 4.277849
#> [8,] 4.844606 4.294494
#> [9,] 4.892119 3.912932
#> [10,] 4.131358 3.933419
#> [11,] 4.149245 4.923175
#> [12,] 4.290106 5.139565
#> [13,] 4.008944 4.115237
#> [14,] 4.565120 3.888604
#> [15,] 4.338737 3.948784
#> [16,] 4.524315 4.008963
#> CAGCCGAAGTTAACGA-500.2.1 CAGCTGGAGATGCCAG-500.2.1
#> [1,] 4.598504 4.365365
#> [2,] 4.405237 4.161161
#> [3,] 4.356608 4.583584
#> [4,] 4.619701 4.781782
#> [5,] 4.293017 4.719720
#> [6,] 4.208229 4.157157
#> [7,] 3.871571 4.443443
#> [8,] 4.844140 4.661662
#> [9,] 4.640898 4.785786
#> [10,] 4.365337 4.301301
#> [11,] 4.216958 4.458458
#> [12,] 4.304239 4.546547
#> [13,] 4.235661 4.335335
#> [14,] 4.600998 3.928929
#> [15,] 4.221945 4.318318
#> [16,] 4.107232 4.271271
#> CAGGTGCAGGTAGCTG-500.2.1 CAGGTGCCACCGCTAG-500.2.1
#> [1,] 4.381805 4.226436
#> [2,] 4.613181 4.404117
#> [3,] 4.415473 4.430119
#> [4,] 4.523639 4.634886
#> [5,] 4.300143 4.411701
#> [6,] 4.118195 4.110509
#> [7,] 4.159742 4.294691
#> [8,] 4.942693 4.916576
#> [9,] 4.825215 4.618635
#> [10,] 4.477077 4.327194
#> [11,] 4.126074 4.494041
#> [12,] 4.345989 4.344529
#> [13,] 4.522206 4.315276
#> [14,] 4.261461 4.704225
#> [15,] 4.584527 4.391116
#> [16,] 4.241404 4.408451
#> CAGTCCTAGGCCCTCA-500.2.1 CAGTCCTCAACTGGCC-500.2.1
#> [1,] 4.800399 4.408560
#> [2,] 5.001996 4.439689
#> [3,] 4.342315 4.459144
#> [4,] 4.195609 4.888457
#> [5,] 4.332335 4.297017
#> [6,] 4.831337 3.948119
#> [7,] 4.217565 4.049287
#> [8,] 4.414172 5.140078
#> [9,] 4.167665 4.940337
#> [10,] 4.000998 4.549935
#> [11,] 4.221557 4.006485
#> [12,] 4.661677 4.485084
#> [13,] 4.467066 4.490272
#> [14,] 4.412176 4.352789
#> [15,] 4.000000 4.317769
#> [16,] 4.100798 4.456550
#> CAGTCCTTCGCGGATC-500.2.1 CATATGGGTCTTCGTC-500.2.1
#> [1,] 5.042254 4.263542
#> [2,] 5.252515 4.416667
#> [3,] 4.418511 4.794792
#> [4,] 4.273642 4.707292
#> [5,] 4.108652 4.478125
#> [6,] 4.473843 4.498958
#> [7,] 4.020121 4.294792
#> [8,] 4.481891 5.106250
#> [9,] 4.019115 4.637500
#> [10,] 4.621730 4.318750
#> [11,] 4.543260 4.291667
#> [12,] 5.047284 4.351042
#> [13,] 4.282696 4.383333
#> [14,] 3.921529 4.264583
#> [15,] 3.813883 4.126042
#> [16,] 3.972837 4.350000
#> CATATGGTCTAACTTC-500.2.1 CATCAAGTCATGTAGC-500.2.1
#> [1,] 4.459544 4.366057
#> [2,] 4.688797 4.130616
#> [3,] 4.604772 4.455907
#> [4,] 4.199170 4.376872
#> [5,] 4.715768 4.483361
#> [6,] 4.322614 4.890183
#> [7,] 4.575726 4.168053
#> [8,] 4.825726 5.113145
#> [9,] 4.548755 4.679700
#> [10,] 4.405602 4.588186
#> [11,] 4.311203 4.307820
#> [12,] 4.831950 4.148087
#> [13,] 4.690871 4.217138
#> [14,] 4.073651 4.420965
#> [15,] 4.461618 4.228785
#> [16,] 4.244813 4.337770
#> CATCAGAGTGCCTTGG-500.2.1 CATCAGATCATTGCGA-500.2.1
#> [1,] 4.398219 4.368992
#> [2,] 4.199746 3.996124
#> [3,] 4.543257 4.459690
#> [4,] 4.297710 4.131008
#> [5,] 4.596692 4.542636
#> [6,] 4.267176 5.162791
#> [7,] 4.188295 4.045736
#> [8,] 4.655216 5.017054
#> [9,] 4.492366 4.739535
#> [10,] 4.419847 4.461240
#> [11,] 4.360051 4.707752
#> [12,] 4.583969 4.477519
#> [13,] 4.437659 3.960465
#> [14,] 4.348601 4.817054
#> [15,] 4.202290 4.354264
#> [16,] 4.660305 4.658915
#> CATCGGGAGAAACCTA-500.2.1 CATGCCTGTTGCTCCT-500.2.1
#> [1,] 4.396855 4.451743
#> [2,] 4.384829 4.116622
#> [3,] 4.595745 4.662198
#> [4,] 4.448659 4.459786
#> [5,] 4.277521 4.676944
#> [6,] 4.077706 4.274799
#> [7,] 4.481036 4.325737
#> [8,] 4.832562 4.855228
#> [9,] 4.569843 4.521448
#> [10,] 4.481961 4.097855
#> [11,] 4.395930 4.475871
#> [12,] 4.418131 4.352547
#> [13,] 4.357077 4.541555
#> [14,] 4.562442 4.357909
#> [15,] 4.219241 3.916890
#> [16,] 4.511563 4.427614
#> CATGGCGTCTCAAGTG-500.2.1 CATTATCGTGTTCGAT-500.2.1
#> [1,] 4.419865 4.389841
#> [2,] 4.139955 4.503060
#> [3,] 4.540632 4.417993
#> [4,] 4.786682 4.469400
#> [5,] 4.287810 4.657895
#> [6,] 4.128668 4.375153
#> [7,] 4.273138 4.264382
#> [8,] 4.600451 5.148715
#> [9,] 4.777652 4.600367
#> [10,] 4.721219 4.282130
#> [11,] 4.322799 4.520808
#> [12,] 4.500000 4.567319
#> [13,] 4.102709 4.443084
#> [14,] 4.400677 4.462668
#> [15,] 4.239278 4.221542
#> [16,] 4.204289 4.308446
#> CCACGGAAGATCCGAG-500.2.1 CCACGGAAGTGTGAAT-500.2.1
#> [1,] 4.145192 4.188616
#> [2,] 4.449038 4.406250
#> [3,] 4.526923 4.340402
#> [4,] 4.271154 4.613839
#> [5,] 4.470192 4.495536
#> [6,] 4.225000 4.107143
#> [7,] 4.285577 4.338170
#> [8,] 4.904808 4.845982
#> [9,] 4.646154 4.776786
#> [10,] 4.386538 4.525670
#> [11,] 4.309615 4.530134
#> [12,] 4.424038 4.256696
#> [13,] 4.680769 4.685268
#> [14,] 4.224038 4.662946
#> [15,] 4.183654 4.246652
#> [16,] 4.439423 4.424107
#> CCACGGAGTACAAGTA-500.2.1 CCACGGAGTGTTTGGT-500.2.1
#> [1,] 4.469830 4.415829
#> [2,] 4.029877 4.550251
#> [3,] 4.370826 4.792714
#> [4,] 4.261863 4.118090
#> [5,] 4.776216 4.447236
#> [6,] 4.499121 4.133166
#> [7,] 3.885179 4.260050
#> [8,] 4.859988 4.688442
#> [9,] 4.466901 4.491206
#> [10,] 4.383714 4.115578
#> [11,] 4.510838 4.148241
#> [12,] 4.314587 4.452261
#> [13,] 4.193322 4.345477
#> [14,] 4.567077 4.211055
#> [15,] 4.212068 4.505025
#> [16,] 4.416520 4.407035
#> CCAGCGAAGTGAAGTT-500.2.1 CCATGTCAGCCCTAAT-500.2.1
#> [1,] 4.535197 4.388889
#> [2,] 4.435818 4.100926
#> [3,] 4.412008 4.377778
#> [4,] 4.505176 4.443519
#> [5,] 4.410973 4.639815
#> [6,] 4.280538 4.191667
#> [7,] 4.208075 4.093519
#> [8,] 4.992754 4.825000
#> [9,] 4.636646 4.683333
#> [10,] 4.527950 4.134259
#> [11,] 4.442029 4.360185
#> [12,] 4.614907 4.647222
#> [13,] 4.340580 4.366667
#> [14,] 4.373706 4.290741
#> [15,] 4.479296 4.462037
#> [16,] 4.233954 4.341667
#> CCATGTCTCTTTCCTC-500.2.1 CCATTCGTCTAACCGA-500.2.1
#> [1,] 4.107483 4.589686
#> [2,] 4.217687 4.241031
#> [3,] 4.507483 4.363229
#> [4,] 4.398639 4.421525
#> [5,] 4.424490 4.521300
#> [6,] 4.246259 4.154709
#> [7,] 4.359184 4.042601
#> [8,] 5.027211 4.786996
#> [9,] 4.673469 4.734305
#> [10,] 4.371429 4.007848
#> [11,] 4.179592 4.229821
#> [12,] 4.457143 4.403587
#> [13,] 4.767347 4.604260
#> [14,] 3.961905 4.236547
#> [15,] 4.156463 4.241031
#> [16,] 4.114286 4.434978
#> CCCAATCAGGAATCGC-500.2.1 CCGGGATCAGCTGGCT-500.2.1
#> [1,] 4.429744 4.454177
#> [2,] 4.153846 4.124557
#> [3,] 4.695385 4.508354
#> [4,] 4.447179 4.390380
#> [5,] 4.202051 4.547848
#> [6,] 4.295385 4.624810
#> [7,] 4.059487 4.236456
#> [8,] 4.604103 4.761013
#> [9,] 4.733333 4.550380
#> [10,] 4.384615 4.237975
#> [11,] 4.372308 4.500759
#> [12,] 4.335385 4.407089
#> [13,] 4.598974 4.305823
#> [14,] 4.204103 4.482025
#> [15,] 4.250256 4.137722
#> [16,] 4.330256 4.542278
#> CCGTGGAAGACGCTTT-500.2.1 CCGTTCACATACTCTT-500.2.1
#> [1,] 4.479814 4.409334
#> [2,] 4.468944 4.201989
#> [3,] 4.579969 4.270849
#> [4,] 4.125000 4.802601
#> [5,] 4.857919 4.587605
#> [6,] 4.233696 4.167559
#> [7,] 4.173913 3.992349
#> [8,] 4.731366 4.980107
#> [9,] 4.260870 4.651109
#> [10,] 4.218944 4.434583
#> [11,] 4.400621 4.185157
#> [12,] 4.316770 4.786534
#> [13,] 4.303571 4.368018
#> [14,] 4.266304 4.259373
#> [15,] 4.524068 4.107116
#> [16,] 4.222050 4.416220
#> CCGTTCATCAGTTGAC-500.2.1 CCTCTGAAGTGGTCCC-500.2.1
#> [1,] 4.599275 4.520000
#> [2,] 4.271985 4.605556
#> [3,] 4.363554 4.575556
#> [4,] 4.546691 4.106667
#> [5,] 4.363554 4.721111
#> [6,] 4.048051 4.590000
#> [7,] 4.084316 4.322222
#> [8,] 4.868540 4.680000
#> [9,] 4.974615 4.507778
#> [10,] 4.395286 4.243333
#> [11,] 4.397099 4.325556
#> [12,] 4.304624 4.441111
#> [13,] 4.219402 4.213333
#> [14,] 4.336355 4.442222
#> [15,] 4.354488 4.513333
#> [16,] 4.259293 4.570000
#> CCTTACGAGAGGACGG-500.2.1 CCTTCCCGTTGGACCC-500.2.1
#> [1,] 4.757322 4.44125
#> [2,] 4.155858 4.38750
#> [3,] 4.790795 4.40500
#> [4,] 4.213389 4.56500
#> [5,] 4.276151 4.43250
#> [6,] 4.618201 4.22750
#> [7,] 4.310669 4.52625
#> [8,] 4.720711 5.06250
#> [9,] 4.870293 4.45625
#> [10,] 4.168410 4.39250
#> [11,] 4.387029 4.47750
#> [12,] 4.570084 4.38875
#> [13,] 4.143305 4.48375
#> [14,] 4.370293 4.58875
#> [15,] 4.032427 4.37250
#> [16,] 4.372385 4.48250
#> CCTTCGACAATCACAC-500.2.1 CCTTTCTAGTTTCCTT-500.2.1
#> [1,] 3.910615 4.717264
#> [2,] 4.653631 4.144287
#> [3,] 4.582402 4.516264
#> [4,] 4.155028 4.180984
#> [5,] 4.148045 4.765638
#> [6,] 4.135475 4.663887
#> [7,] 4.304469 4.213511
#> [8,] 4.747207 4.969975
#> [9,] 4.750000 4.795663
#> [10,] 4.744413 4.366138
#> [11,] 4.459497 4.565471
#> [12,] 4.361732 4.563803
#> [13,] 4.497207 4.215179
#> [14,] 4.185754 4.402836
#> [15,] 4.374302 4.076731
#> [16,] 4.416201 4.457048
#> CGACCTTTCCTCTAGC-500.2.1 CGAGAAGTCACCACCT-500.2.1
#> [1,] 4.150160 4.646026
#> [2,] 4.343983 3.891867
#> [3,] 4.534611 4.576710
#> [4,] 4.345048 4.134011
#> [5,] 4.127796 4.731978
#> [6,] 4.026624 5.035120
#> [7,] 4.175719 4.355823
#> [8,] 4.981896 4.935305
#> [9,] 4.648562 4.680222
#> [10,] 4.466454 4.375231
#> [11,] 4.308839 4.727357
#> [12,] 4.609159 4.593346
#> [13,] 4.564430 3.913124
#> [14,] 4.372737 4.612754
#> [15,] 4.364217 4.219039
#> [16,] 4.469649 4.595194
#> CGAGCCAAGAAGGCCT-500.2.1 CGAGCCATCGACAGCC-500.2.1
#> [1,] 4.622285 4.376901
#> [2,] 5.035883 4.148732
#> [3,] 4.220019 4.194930
#> [4,] 4.222852 4.448451
#> [5,] 4.133144 4.569577
#> [6,] 4.593012 4.520000
#> [7,] 4.123702 3.991549
#> [8,] 5.159585 4.990423
#> [9,] 4.381492 4.684507
#> [10,] 4.594901 4.299718
#> [11,] 4.552408 4.372394
#> [12,] 4.450425 4.548169
#> [13,] 4.462701 4.086197
#> [14,] 4.293673 4.529577
#> [15,] 3.957507 4.310423
#> [16,] 4.046270 4.305915
#> CGATCGGAGAGGTACC-500.2.1 CGATGTAAGAGACTTA-500.2.1
#> [1,] 4.716926 4.511416
#> [2,] 4.212062 4.016438
#> [3,] 4.200389 3.963470
#> [4,] 4.534047 4.887671
#> [5,] 4.356031 4.837443
#> [6,] 4.346304 4.076712
#> [7,] 3.966926 4.684018
#> [8,] 4.970817 4.491324
#> [9,] 4.487354 4.339726
#> [10,] 4.236381 4.642922
#> [11,] 4.352140 4.272146
#> [12,] 4.581712 4.834703
#> [13,] 4.233463 4.642009
#> [14,] 4.543774 4.744292
#> [15,] 4.316148 4.281279
#> [16,] 4.218872 4.117808
#> CGATGTAGTATTCGTG-500.2.1 CGATTGATCAGCATGT-500.2.1
#> [1,] 4.600837 4.290468
#> [2,] 4.204466 4.221223
#> [3,] 4.188416 4.760791
#> [4,] 4.155618 4.207734
#> [5,] 4.443126 4.757194
#> [6,] 4.027216 4.195144
#> [7,] 4.297278 3.942446
#> [8,] 4.727844 5.020683
#> [9,] 4.738311 4.875899
#> [10,] 4.233077 4.356115
#> [11,] 4.394976 4.133993
#> [12,] 4.483601 4.344424
#> [13,] 4.345429 4.388489
#> [14,] 4.166783 4.514388
#> [15,] 4.258897 4.018885
#> [16,] 4.588276 4.361511
#> CGCCAAGCACAGGAGT-500.2.1 CGCGTTTCAAGGTTTC-500.2.1
#> [1,] 4.336966 3.948444
#> [2,] 4.059037 3.984889
#> [3,] 4.520436 4.126222
#> [4,] 4.693006 3.984000
#> [5,] 4.386013 4.256889
#> [6,] 4.221617 5.232000
#> [7,] 3.981835 3.955556
#> [8,] 4.771117 4.488889
#> [9,] 5.241599 4.285333
#> [10,] 4.599455 4.288000
#> [11,] 4.386013 4.048000
#> [12,] 4.383288 4.384889
#> [13,] 4.235241 4.335111
#> [14,] 4.243415 4.986667
#> [15,] 4.300636 3.973333
#> [16,] 4.168937 5.047111
#> CGCTATCCAATAAGCA-500.2.1 CGCTGGAAGGCAGTCA-500.2.1
#> [1,] 4.693174 4.237500
#> [2,] 4.191518 4.331818
#> [3,] 4.325381 4.379545
#> [4,] 4.184891 4.023864
#> [5,] 4.518887 4.987500
#> [6,] 4.448641 4.840909
#> [7,] 4.216037 3.761364
#> [8,] 5.058317 4.998864
#> [9,] 4.722333 4.511364
#> [10,] 4.516899 4.100000
#> [11,] 4.349901 4.561364
#> [12,] 4.608350 4.446591
#> [13,] 4.304175 4.629545
#> [14,] 4.609013 3.919318
#> [15,] 4.297548 3.911364
#> [16,] 4.337309 4.748864
#> CGCTGGAGTAGAAGGA-500.2.1 CGGACGTAGTCGTACT-500.2.1
#> [1,] 4.522099 4.648327
#> [2,] 4.162983 4.210409
#> [3,] 4.484807 4.731599
#> [4,] 4.504144 4.179182
#> [5,] 4.653315 4.418587
#> [6,] 4.515193 3.929368
#> [7,] 4.243094 4.117472
#> [8,] 5.033149 4.715985
#> [9,] 4.650552 4.244610
#> [10,] 4.428177 3.903346
#> [11,] 4.229282 4.184387
#> [12,] 4.403315 4.440892
#> [13,] 4.529006 4.423792
#> [14,] 4.194751 4.069888
#> [15,] 4.087017 4.287732
#> [16,] 4.468232 4.125651
#> CGGAGCTTCGAATGGG-500.2.1 CGGCTAGTCTTTACGT-500.2.1
#> [1,] 4.388005 4.239731
#> [2,] 4.428397 4.246453
#> [3,] 4.487148 4.469007
#> [4,] 4.472460 4.421957
#> [5,] 4.275398 4.123226
#> [6,] 4.019584 4.223301
#> [7,] 3.986536 3.840926
#> [8,] 4.850673 4.687827
#> [9,] 4.778458 4.727409
#> [10,] 4.286414 4.686333
#> [11,] 4.263158 4.427184
#> [12,] 4.522644 4.248693
#> [13,] 4.729498 4.334578
#> [14,] 4.652387 4.203883
#> [15,] 4.047736 4.482450
#> [16,] 4.122399 4.211352
#> CGTAGGCTCATATCGG-500.2.1 CGTAGGCTCTATCCTA-500.2.1
#> [1,] 4.558052 4.035800
#> [2,] 4.142322 4.313842
#> [3,] 4.697566 4.671838
#> [4,] 4.239700 4.568019
#> [5,] 4.806180 4.606205
#> [6,] 4.748127 4.399761
#> [7,] 4.358614 4.121718
#> [8,] 4.686330 4.752983
#> [9,] 4.558052 4.729117
#> [10,] 4.292135 4.884248
#> [11,] 4.718165 4.375895
#> [12,] 4.742509 4.446301
#> [13,] 3.858614 4.102625
#> [14,] 4.494382 4.260143
#> [15,] 4.470037 4.322196
#> [16,] 4.545880 4.307876
#> CGTCACTTCTCGAGTA-500.2.1 CGTGTCTAGCAACGGT-500.2.1
#> [1,] 4.624076 4.401115
#> [2,] 4.379092 4.119703
#> [3,] 4.314678 4.481784
#> [4,] 4.576558 4.405948
#> [5,] 4.538543 4.457993
#> [6,] 3.887012 4.358736
#> [7,] 4.423442 3.980669
#> [8,] 4.524815 4.890335
#> [9,] 4.597677 4.834201
#> [10,] 4.952482 4.605204
#> [11,] 4.589229 4.191078
#> [12,] 4.180570 4.336059
#> [13,] 4.354805 4.382156
#> [14,] 4.593453 4.597026
#> [15,] 5.091869 4.240149
#> [16,] 3.945090 4.465799
#> CGTTAGAAGAACAACT-500.2.1 CGTTAGACAATAAGCA-500.2.1
#> [1,] 4.570776 4.592593
#> [2,] 4.444227 4.324786
#> [3,] 4.374429 4.680912
#> [4,] 4.169602 4.299145
#> [5,] 4.761905 4.679012
#> [6,] 4.479452 3.921178
#> [7,] 4.151337 4.036087
#> [8,] 4.863014 4.766382
#> [9,] 4.926941 4.507123
#> [10,] 4.313764 4.456790
#> [11,] 4.750815 4.307692
#> [12,] 4.613829 4.537512
#> [13,] 4.350294 4.559354
#> [14,] 4.443575 4.511871
#> [15,] 4.231572 4.057930
#> [16,] 4.566862 4.226971
#> CTAAGACGTGTGAAAT-500.2.1 CTACACCAGCGATCCC-500.2.1
#> [1,] 4.021077 4.530303
#> [2,] 4.454333 5.047786
#> [3,] 4.338407 4.371795
#> [4,] 4.565574 4.297203
#> [5,] 4.412178 4.153846
#> [6,] 4.443794 5.085082
#> [7,] 4.189696 4.270396
#> [8,] 4.571429 4.716783
#> [9,] 4.733021 3.961538
#> [10,] 4.240047 4.581585
#> [11,] 4.127635 4.235431
#> [12,] 4.333724 4.747086
#> [13,] 4.440281 4.327506
#> [14,] 4.569087 4.393939
#> [15,] 3.962529 3.905594
#> [16,] 4.489461 4.248252
#> CTACCCACATTACCTT-500.2.1 CTAGTGATCGTCCAGG-500.2.1
#> [1,] 4.291705 4.498656
#> [2,] 4.249767 4.110215
#> [3,] 4.380242 4.412634
#> [4,] 4.463187 4.506720
#> [5,] 4.646785 4.485215
#> [6,] 4.414725 3.930108
#> [7,] 4.007456 4.396505
#> [8,] 4.637465 4.510753
#> [9,] 4.689655 4.901882
#> [10,] 4.265610 4.364247
#> [11,] 4.619758 4.418011
#> [12,] 4.340168 4.666667
#> [13,] 4.538677 4.213710
#> [14,] 4.183597 4.491935
#> [15,] 3.986021 4.353495
#> [16,] 4.163094 4.494624
#> CTAGTGATCTACGAGT-500.2.1 CTCACACTCAATCTCT-500.2.1
#> [1,] 4.358362 4.776866
#> [2,] 4.288965 4.144030
#> [3,] 4.482366 4.439552
#> [4,] 4.367463 4.429851
#> [5,] 4.466439 4.685821
#> [6,] 4.240046 4.713433
#> [7,] 4.584755 4.197015
#> [8,] 4.703072 4.532836
#> [9,] 4.737201 4.794030
#> [10,] 4.270762 4.382090
#> [11,] 4.352673 4.682090
#> [12,] 4.729238 4.610448
#> [13,] 4.569966 4.113433
#> [14,] 4.284414 4.526866
#> [15,] 4.109215 4.317910
#> [16,] 4.265074 4.481343
#> CTCAGAATCCAATGGT-500.2.1 CTCAGAATCTGTGCAA-500.2.1
#> [1,] 4.421831 4.496923
#> [2,] 4.276056 4.153846
#> [3,] 4.380986 4.328462
#> [4,] 4.388732 4.434615
#> [5,] 4.519718 4.491538
#> [6,] 4.257746 4.389231
#> [7,] 4.171127 4.355385
#> [8,] 4.864789 4.995385
#> [9,] 4.900000 4.660000
#> [10,] 4.519718 4.426923
#> [11,] 4.294366 4.588462
#> [12,] 4.384507 4.273077
#> [13,] 4.352817 4.356154
#> [14,] 4.490141 4.451538
#> [15,] 3.923944 4.415385
#> [16,] 4.580986 4.135385
#> CTCGAAAAGTGAACGC-500.2.1 CTCGGAGCACCGGAAA-500.2.1
#> [1,] 4.555830 4.483636
#> [2,] 4.716841 3.876364
#> [3,] 4.401604 4.490000
#> [4,] 4.386181 4.116364
#> [5,] 4.549661 4.670909
#> [6,] 4.629858 4.670909
#> [7,] 4.046885 3.962727
#> [8,] 4.647748 4.792727
#> [9,] 4.640345 4.693636
#> [10,] 4.569402 4.476364
#> [11,] 4.611351 4.765455
#> [12,] 4.594695 4.560909
#> [13,] 4.204195 3.920909
#> [14,] 4.404072 4.770909
#> [15,] 4.360888 4.422727
#> [16,] 3.974707 4.465455
#> CTCTAATAGATCTGCT-500.2.1 CTCTAATAGCGTGAAC-500.2.1
#> [1,] 4.239598 4.477077
#> [2,] 4.513630 4.402579
#> [3,] 4.354376 4.090258
#> [4,] 4.543759 4.790831
#> [5,] 4.268293 4.681948
#> [6,] 4.149211 4.525788
#> [7,] 4.065997 4.224928
#> [8,] 4.794835 4.663324
#> [9,] 4.974175 4.382521
#> [10,] 4.189383 3.981375
#> [11,] 4.256815 4.372493
#> [12,] 4.319943 4.375358
#> [13,] 4.542324 4.242120
#> [14,] 4.804878 4.604585
#> [15,] 3.895265 4.375358
#> [16,] 4.582496 4.343840
#> CTCTACGAGAAGGCCT-500.2.1 CTCTACGAGTACTTGC-500.2.1
#> [1,] 4.413823 4.525570
#> [2,] 4.290464 4.333596
#> [3,] 4.568679 4.241542
#> [4,] 4.125984 4.511408
#> [5,] 4.531059 4.214005
#> [6,] 4.447069 4.387097
#> [7,] 4.234471 3.784422
#> [8,] 4.787402 5.178600
#> [9,] 4.630796 5.564123
#> [10,] 4.355206 4.529504
#> [11,] 4.354331 4.621558
#> [12,] 4.522310 4.175452
#> [13,] 4.198600 4.180960
#> [14,] 4.330709 4.151849
#> [15,] 4.104112 4.107789
#> [16,] 4.336833 4.342250
#> CTCTACGTCTAACCGA-500.2.1 CTGAAGTAGGTAGCCA-500.2.1
#> [1,] 4.559361 4.404323
#> [2,] 4.691781 4.028022
#> [3,] 4.391553 4.156125
#> [4,] 4.276256 4.815853
#> [5,] 4.571918 4.597278
#> [6,] 4.444064 4.291433
#> [7,] 4.079909 3.979984
#> [8,] 4.772831 4.903923
#> [9,] 4.670091 4.883907
#> [10,] 4.496575 4.928743
#> [11,] 4.462329 4.096878
#> [12,] 4.374429 4.471577
#> [13,] 4.485160 4.296237
#> [14,] 4.528539 4.052042
#> [15,] 4.340183 4.132906
#> [16,] 4.425799 4.219376
#> CTGATAGGTATGCTTG-500.2.1 CTGATCCCAGCTGCAC-500.2.1
#> [1,] 4.468652 4.181065
#> [2,] 4.359718 4.413018
#> [3,] 4.538401 4.584615
#> [4,] 3.956897 4.489349
#> [5,] 4.700627 4.928994
#> [6,] 4.371473 4.303550
#> [7,] 4.157524 4.122485
#> [8,] 4.879310 5.171006
#> [9,] 4.839342 4.586391
#> [10,] 4.317398 4.776923
#> [11,] 4.363636 4.418343
#> [12,] 4.257053 4.536095
#> [13,] 4.265674 4.591124
#> [14,] 4.310345 4.123077
#> [15,] 4.103448 4.443787
#> [16,] 4.565831 4.328994
#> CTGCGGACAACGATGG-500.2.1 CTGGTCTGTCTAAAGA-500.2.1
#> [1,] 4.459694 4.287037
#> [2,] 4.291139 4.273148
#> [3,] 4.415723 4.636574
#> [4,] 4.383744 4.145833
#> [5,] 4.593604 4.649306
#> [6,] 4.201865 4.451389
#> [7,] 3.948035 4.230324
#> [8,] 4.984011 4.922454
#> [9,] 5.009993 4.523148
#> [10,] 4.161892 4.454861
#> [11,] 4.232512 4.752315
#> [12,] 4.336442 4.792824
#> [13,] 4.343105 4.497685
#> [14,] 4.455030 4.535880
#> [15,] 3.932712 4.262731
#> [16,] 4.363091 4.593750
#> CTGTTTAGTTAAAGTG-500.2.1 CTTACCGCATGACATC-500.2.1
#> [1,] 4.523098 4.756784
#> [2,] 3.910326 4.018090
#> [3,] 4.572011 4.386935
#> [4,] 4.013587 4.260302
#> [5,] 4.362772 4.778894
#> [6,] 4.260870 3.979899
#> [7,] 4.425272 4.138693
#> [8,] 4.744565 5.012060
#> [9,] 4.698370 4.794975
#> [10,] 4.054348 3.945729
#> [11,] 4.396739 4.102513
#> [12,] 4.716033 4.271357
#> [13,] 4.308424 4.787940
#> [14,] 4.366848 4.179899
#> [15,] 4.133152 4.349749
#> [16,] 4.506793 4.278392
#> CTTAGGAAGCACAGGT-500.2.1 CTTAGGAAGGAATGGA-500.2.1
#> [1,] 3.959770 4.257708
#> [2,] 3.930213 4.225296
#> [3,] 4.646962 4.517787
#> [4,] 4.673235 4.593676
#> [5,] 4.738095 4.478261
#> [6,] 4.185550 4.500395
#> [7,] 4.039409 4.096443
#> [8,] 4.977011 4.884585
#> [9,] 4.887521 4.775494
#> [10,] 4.275862 4.531225
#> [11,] 4.359606 4.407905
#> [12,] 4.277504 4.480632
#> [13,] 4.540230 4.518577
#> [14,] 4.276683 4.562846
#> [15,] 3.986864 3.938340
#> [16,] 4.300493 4.309091
#> CTTCTCTAGGCAATTA-500.2.1 CTTTGCGAGCGTGAGT-500.2.1
#> [1,] 4.267708 4.720648
#> [2,] 4.050000 4.394332
#> [3,] 4.351042 4.429960
#> [4,] 5.056250 4.563563
#> [5,] 4.543750 4.261538
#> [6,] 4.617708 4.091498
#> [7,] 3.942708 4.204858
#> [8,] 5.235417 4.352227
#> [9,] 5.350000 4.386235
#> [10,] 4.830208 4.690688
#> [11,] 4.173958 4.404858
#> [12,] 4.213542 4.279352
#> [13,] 4.013542 4.296356
#> [14,] 4.461458 4.445344
#> [15,] 3.921875 4.631579
#> [16,] 4.288542 3.970850
#> CTTTGCGAGCTAGTCT-500.2.1 GAACATCCATCACGTA-500.2.1
#> [1,] 4.214502 4.510610
#> [2,] 4.757301 4.348806
#> [3,] 4.464250 4.302387
#> [4,] 4.516616 4.620690
#> [5,] 4.144008 4.555703
#> [6,] 4.008056 4.403183
#> [7,] 4.048338 4.311671
#> [8,] 4.810675 4.706897
#> [9,] 5.120846 4.734748
#> [10,] 4.921450 4.468170
#> [11,] 4.261833 4.324934
#> [12,] 4.359517 4.379310
#> [13,] 4.277946 4.185676
#> [14,] 4.206445 4.448276
#> [15,] 5.244713 4.547745
#> [16,] 4.024169 4.087533
#> GACAGAGAGCCGGTAA-500.2.1 GACCTGGAGATACACA-500.2.1
#> [1,] 4.677384 4.391870
#> [2,] 4.195122 4.292683
#> [3,] 4.375831 4.291870
#> [4,] 4.454545 4.402439
#> [5,] 4.833703 4.557724
#> [6,] 4.172949 4.386179
#> [7,] 4.226164 3.963415
#> [8,] 4.901330 5.143089
#> [9,] 4.702882 4.920325
#> [10,] 4.079823 4.216260
#> [11,] 4.282705 4.266667
#> [12,] 4.396896 4.313008
#> [13,] 4.601996 4.508943
#> [14,] 3.661863 4.386992
#> [15,] 3.988914 4.143089
#> [16,] 4.281596 4.369106
#> GACGCGTCAAATTGCC-500.2.1 GACGTGCAGCGATATA-500.2.1
#> [1,] 4.248644 4.618659
#> [2,] 4.367089 4.034420
#> [3,] 4.713382 4.437500
#> [4,] 4.410488 4.482790
#> [5,] 4.390597 4.763587
#> [6,] 4.611212 5.002717
#> [7,] 4.223327 4.077899
#> [8,] 5.043400 4.458333
#> [9,] 4.583183 4.925725
#> [10,] 4.496383 4.353261
#> [11,] 4.515371 4.994565
#> [12,] 4.520796 4.330616
#> [13,] 4.160940 3.884964
#> [14,] 4.563291 4.415761
#> [15,] 4.084991 4.320652
#> [16,] 4.464738 4.614130
#> GACGTGCGTACCGAGA-500.2.1 GACGTGCTCATCGCTC-500.2.1
#> [1,] 4.374207 4.671771
#> [2,] 3.949260 4.155792
#> [3,] 4.619450 4.643142
#> [4,] 4.520085 4.350866
#> [5,] 4.496829 4.361518
#> [6,] 4.575053 4.132490
#> [7,] 3.780127 4.145806
#> [8,] 4.918605 4.880826
#> [9,] 5.156448 4.589214
#> [10,] 4.581395 4.163116
#> [11,] 4.406977 4.373502
#> [12,] 4.152220 4.332224
#> [13,] 4.449260 4.416112
#> [14,] 4.151163 4.276964
#> [15,] 4.182875 3.953395
#> [16,] 4.707188 4.275632
#> GACGTTATCGTATCAG-500.2.1 GACTAACAGTGTCCAT-500.2.1
#> [1,] 4.557126 4.491094
#> [2,] 4.469965 4.290076
#> [3,] 4.658422 4.735369
#> [4,] 3.976443 4.613232
#> [5,] 4.498233 4.300254
#> [6,] 4.117786 4.405852
#> [7,] 4.302709 4.076336
#> [8,] 4.930506 5.217557
#> [9,] 4.760895 4.840967
#> [10,] 4.118963 4.237913
#> [11,] 4.418139 4.394402
#> [12,] 4.289753 4.407125
#> [13,] 4.373380 4.274809
#> [14,] 4.114252 4.534351
#> [15,] 4.095406 4.119593
#> [16,] 4.234393 4.390585
#> GACTACATCTGCGTAA-500.2.1 GAGGTGAGTTCAGCGC-500.2.1
#> [1,] 4.363870 4.174079
#> [2,] 4.244007 4.355781
#> [3,] 4.636130 4.465057
#> [4,] 4.151541 4.762389
#> [5,] 4.821062 4.470140
#> [6,] 4.613014 4.297332
#> [7,] 4.145548 4.170267
#> [8,] 5.089041 4.631512
#> [9,] 4.553082 4.750953
#> [10,] 4.151541 4.503177
#> [11,] 4.836473 4.429479
#> [12,] 4.303082 4.235070
#> [13,] 4.255993 4.458704
#> [14,] 4.577055 4.299873
#> [15,] 4.262842 4.015248
#> [16,] 4.333904 4.651842
#> GAGTCCGAGTCCTCCT-500.2.1 GAGTCCGGTGACCAAG-500.2.1
#> [1,] 4.372718 4.308390
#> [2,] 4.238453 4.385488
#> [3,] 4.660580 4.480726
#> [4,] 4.760473 4.496599
#> [5,] 4.250269 4.531746
#> [6,] 4.206230 4.403628
#> [7,] 4.408163 4.345805
#> [8,] 4.601504 4.553288
#> [9,] 4.617615 4.835601
#> [10,] 4.437164 4.302721
#> [11,] 4.257787 4.462585
#> [12,] 4.303974 4.679138
#> [13,] 4.404941 4.388889
#> [14,] 4.476907 4.289116
#> [15,] 4.253491 4.068027
#> [16,] 4.123523 4.297052
#> GATCAGTCAACACCTA-500.2.1 GATCGCGTCAGCAACT-500.2.1
#> [1,] 4.597701 4.200175
#> [2,] 3.977011 4.428322
#> [3,] 4.533844 4.440559
#> [4,] 4.231162 4.251748
#> [5,] 4.584930 4.567308
#> [6,] 4.131545 4.617133
#> [7,] 4.080460 4.165210
#> [8,] 4.814815 4.681818
#> [9,] 4.655172 4.589161
#> [10,] 3.971903 4.246503
#> [11,] 4.122605 4.261364
#> [12,] 4.245211 4.633741
#> [13,] 4.731801 4.154720
#> [14,] 4.154534 4.633741
#> [15,] 4.270754 4.253497
#> [16,] 4.379310 4.579545
#> GATGAGGGTCCAGTGC-500.2.1 GATGCTAGTAGCAAAT-500.2.1
#> [1,] 4.467213 4.740868
#> [2,] 4.079918 4.159817
#> [3,] 4.308402 4.649543
#> [4,] 4.304303 4.143836
#> [5,] 4.782787 4.348174
#> [6,] 4.640369 4.450913
#> [7,] 4.264344 4.093607
#> [8,] 5.100410 4.671233
#> [9,] 4.548156 4.582192
#> [10,] 4.507172 4.376712
#> [11,] 4.589139 4.269406
#> [12,] 4.290984 4.286530
#> [13,] 4.324795 4.777397
#> [14,] 4.625000 4.219178
#> [15,] 4.380123 3.953196
#> [16,] 4.150615 4.190639
#> GATTCAGCAGCGATCC-500.2.1 GATTCAGCAGTCGTGC-500.2.1
#> [1,] 4.575074 4.535411
#> [2,] 4.362120 4.682720
#> [3,] 4.773307 4.651558
#> [4,] 4.382728 4.699717
#> [5,] 4.452404 4.648725
#> [6,] 4.166830 4.474504
#> [7,] 3.968597 4.580737
#> [8,] 4.795878 4.729462
#> [9,] 4.708538 4.762040
#> [10,] 4.103042 4.716714
#> [11,] 4.121688 4.440510
#> [12,] 4.665358 4.626062
#> [13,] 4.819431 4.138810
#> [14,] 4.153091 4.485836
#> [15,] 3.980373 4.058074
#> [16,] 4.514230 4.420680
#> GCAAACTGTGTATGGG-500.2.1 GCAATCAGTAAACGCG-500.2.1
#> [1,] 4.352034 4.483673
#> [2,] 4.428471 3.825510
#> [3,] 4.444600 4.478571
#> [4,] 4.407433 4.076531
#> [5,] 4.321178 4.760204
#> [6,] 4.139551 4.778571
#> [7,] 4.315568 4.177551
#> [8,] 4.781907 4.842857
#> [9,] 4.603787 4.760204
#> [10,] 4.570126 4.465306
#> [11,] 4.479663 4.973469
#> [12,] 4.467041 4.271429
#> [13,] 4.381487 4.112245
#> [14,] 4.265778 4.762245
#> [15,] 4.194250 4.204082
#> [16,] 4.281206 4.936735
#> GCAGCCATCAGGTAAA-500.2.1 GCATACAGTCATTAGC-500.2.1
#> [1,] 4.713277 4.243031
#> [2,] 5.201977 4.375436
#> [3,] 4.570621 4.514808
#> [4,] 4.138418 4.335366
#> [5,] 4.187853 4.405923
#> [6,] 4.932203 4.195993
#> [7,] 4.137006 3.979094
#> [8,] 4.204802 4.679443
#> [9,] 4.274011 4.729965
#> [10,] 4.251412 4.235192
#> [11,] 4.902542 4.316202
#> [12,] 4.785311 4.472125
#> [13,] 3.888418 4.275261
#> [14,] 3.911017 4.350174
#> [15,] 3.830508 4.254355
#> [16,] 4.015537 4.371951
#> GCATGATTCTCGCTTG-500.2.1 GCATGTATCGTTGCCT-500.2.1
#> [1,] 4.557143 4.393681
#> [2,] 4.377444 4.032451
#> [3,] 4.376692 4.345004
#> [4,] 4.285714 4.547395
#> [5,] 4.569925 4.808711
#> [6,] 4.254135 3.941076
#> [7,] 3.973684 3.990606
#> [8,] 5.183459 4.723313
#> [9,] 4.851128 4.936806
#> [10,] 4.266917 4.111016
#> [11,] 4.046617 4.174210
#> [12,] 4.296992 4.151153
#> [13,] 4.436842 4.745517
#> [14,] 4.345865 4.418446
#> [15,] 3.918797 4.167378
#> [16,] 4.530075 4.385141
#> GCCTCTATCAGTCAGT-500.2.1 GCGACCACAAGAGGCT-500.2.1
#> [1,] 4.573840 4.646113
#> [2,] 4.308544 4.343164
#> [3,] 4.469409 4.702413
#> [4,] 4.022152 4.423592
#> [5,] 4.590190 4.958445
#> [6,] 4.309072 4.390080
#> [7,] 4.178270 4.170241
#> [8,] 4.811709 4.941019
#> [9,] 4.561181 4.654155
#> [10,] 4.306435 4.201072
#> [11,] 4.337025 4.289544
#> [12,] 4.572785 4.486595
#> [13,] 4.529008 4.254692
#> [14,] 4.033755 3.899464
#> [15,] 4.087025 4.032172
#> [16,] 4.280591 4.325737
#> GCGACCACACAGTCGC-500.2.1 GCGACCAGTGTTTGGT-500.2.1
#> [1,] 4.396185 3.946704
#> [2,] 4.406456 4.586255
#> [3,] 4.606750 4.556802
#> [4,] 4.545121 3.892006
#> [5,] 4.561996 4.182328
#> [6,] 4.332355 3.952314
#> [7,] 4.021277 4.314165
#> [8,] 5.107850 4.677419
#> [9,] 4.427733 4.976157
#> [10,] 4.058694 4.844320
#> [11,] 4.490095 4.208976
#> [12,] 4.250917 4.270687
#> [13,] 4.223037 4.377279
#> [14,] 4.446075 4.584853
#> [15,] 4.573001 4.702665
#> [16,] 4.178283 4.016830
#> GCGCAGTTCTGATACG-500.2.1 GCGCGATGTTGCGTTA-500.2.1
#> [1,] 4.365209 4.588692
#> [2,] 4.007689 3.875831
#> [3,] 4.541086 4.584257
#> [4,] 4.701586 4.463415
#> [5,] 4.219606 4.560976
#> [6,] 4.442576 4.739468
#> [7,] 3.907256 3.901330
#> [8,] 5.072561 4.797118
#> [9,] 4.981740 4.462306
#> [10,] 4.704950 4.220621
#> [11,] 4.308986 4.339246
#> [12,] 4.255166 4.405765
#> [13,] 4.107160 4.801552
#> [14,] 4.298895 4.289357
#> [15,] 4.439212 4.143016
#> [16,] 4.286401 4.687361
#> GCTGGGTTCATCTGCC-500.2.1 GGAACTTAGCGCCTTG-500.2.1
#> [1,] 4.342653 4.327889
#> [2,] 4.306892 4.732412
#> [3,] 4.842003 4.478643
#> [4,] 4.027308 4.242462
#> [5,] 4.260728 4.394472
#> [6,] 3.967490 4.399497
#> [7,] 3.902471 4.011307
#> [8,] 4.745774 4.910804
#> [9,] 4.779584 4.271357
#> [10,] 4.176853 4.103015
#> [11,] 4.364109 4.575377
#> [12,] 4.642393 4.472362
#> [13,] 4.425878 4.493719
#> [14,] 4.249675 4.136935
#> [15,] 4.312744 4.380653
#> [16,] 4.394668 4.317839
#> GGAACTTGTTCCGTCT-500.2.1 GGACATTGTATGAAAC-500.2.1
#> [1,] 4.574244 4.136300
#> [2,] 4.237845 4.421419
#> [3,] 4.818660 4.600834
#> [4,] 4.362681 4.293463
#> [5,] 4.662286 4.521558
#> [6,] 4.149803 4.162726
#> [7,] 3.955322 4.283727
#> [8,] 4.837057 4.618915
#> [9,] 4.433640 4.497914
#> [10,] 4.266754 4.392211
#> [11,] 4.431012 4.433936
#> [12,] 4.153745 4.240612
#> [13,] 4.706965 4.322670
#> [14,] 4.210250 4.308762
#> [15,] 3.848883 4.048679
#> [16,] 4.526938 4.819193
#> GGATTACCATTGGCGC-500.2.1 GGATTACTCAGCTCTC-500.2.1
#> [1,] 4.526316 4.407809
#> [2,] 4.877667 4.380694
#> [3,] 4.587482 4.622560
#> [4,] 4.466572 4.194143
#> [5,] 3.965861 4.821041
#> [6,] 4.822191 4.081345
#> [7,] 4.125178 4.258134
#> [8,] 4.867710 4.751627
#> [9,] 4.243243 4.516269
#> [10,] 4.246088 4.464208
#> [11,] 4.560455 4.297180
#> [12,] 4.520626 4.451193
#> [13,] 4.584637 4.654013
#> [14,] 4.230441 4.379610
#> [15,] 3.834993 4.123644
#> [16,] 4.137980 4.601952
#> GGCGTGTTCTGCTTGC-500.2.1 GGGCATCGTGGTACAG-500.2.1
#> [1,] 4.208683 4.491269
#> [2,] 4.457983 3.768335
#> [3,] 4.501401 4.343423
#> [4,] 4.626050 4.095460
#> [5,] 4.774510 4.781141
#> [6,] 4.229692 5.039581
#> [7,] 3.952381 4.094296
#> [8,] 5.225490 4.749709
#> [9,] 4.658263 4.623981
#> [10,] 4.133053 4.722934
#> [11,] 4.275910 4.603027
#> [12,] 4.528011 4.394645
#> [13,] 4.920168 4.230501
#> [14,] 4.162465 4.445867
#> [15,] 4.263305 4.074505
#> [16,] 4.217087 4.420256
#> GGGTTGCGTTTAGCTG-500.2.1 GGTGAAGAGGCATTGG-500.2.1
#> [1,] 4.191241 4.128350
#> [2,] 4.191971 4.053597
#> [3,] 4.404380 3.998590
#> [4,] 4.078832 4.056417
#> [5,] 4.299270 4.354020
#> [6,] 4.304380 5.229901
#> [7,] 3.862774 4.014104
#> [8,] 5.303650 4.700987
#> [9,] 4.615328 4.448519
#> [10,] 4.226277 4.314528
#> [11,] 4.505109 4.083216
#> [12,] 4.467883 4.428773
#> [13,] 4.501460 4.433004
#> [14,] 4.395620 4.884344
#> [15,] 4.327007 4.215797
#> [16,] 4.683212 4.624824
#> GGTGCGTCACTTCTGC-500.2.1 GGTGTTAGTGCACGAA-500.2.1
#> [1,] 4.648247 4.535484
#> [2,] 4.429330 4.272811
#> [3,] 4.151966 4.467281
#> [4,] 4.479277 4.287558
#> [5,] 4.738576 4.434101
#> [6,] 4.800213 4.277419
#> [7,] 4.391073 4.224885
#> [8,] 5.056323 4.852535
#> [9,] 4.680128 4.403687
#> [10,] 4.533475 4.213825
#> [11,] 4.637620 4.135484
#> [12,] 4.257173 4.439631
#> [13,] 4.308183 4.554839
#> [14,] 4.167906 4.257143
#> [15,] 4.182784 4.399078
#> [16,] 4.514346 4.517051
#> GTAACGTCAGCCTTTC-500.2.1 GTAACTGCAGCTCGAC-500.2.1
#> [1,] 4.441211 4.561003
#> [2,] 4.003492 4.339795
#> [3,] 4.378347 4.474344
#> [4,] 4.166473 4.870011
#> [5,] 4.577416 4.824401
#> [6,] 4.121071 4.282782
#> [7,] 4.223516 4.234892
#> [8,] 4.923166 4.641961
#> [9,] 4.703143 4.673888
#> [10,] 4.260768 4.592930
#> [11,] 4.298021 4.633979
#> [12,] 4.401630 4.446978
#> [13,] 4.472643 4.477765
#> [14,] 4.253783 4.411631
#> [15,] 4.218859 4.239453
#> [16,] 4.301513 4.247434
#> GTACGTAGTCATGCCG-500.2.1 GTACTTTTCACGAAGG-500.2.1
#> [1,] 4.636802 4.543970
#> [2,] 4.227360 4.412060
#> [3,] 4.687861 4.586683
#> [4,] 4.308285 4.219849
#> [5,] 4.461464 4.469849
#> [6,] 4.390173 4.533920
#> [7,] 4.370906 4.233668
#> [8,] 4.578998 4.902010
#> [9,] 4.538536 4.643216
#> [10,] 4.504817 4.355528
#> [11,] 4.534682 4.484925
#> [12,] 4.439306 4.791457
#> [13,] 4.178227 4.213568
#> [14,] 4.347784 4.332915
#> [15,] 4.236994 4.256281
#> [16,] 4.186898 4.305276
#> GTATCTTTCGTTTATC-500.2.1 GTCAAGTCAATAAGCA-500.2.1
#> [1,] 4.225543 4.464525
#> [2,] 4.304348 4.341365
#> [3,] 4.642663 4.293173
#> [4,] 4.264946 4.066934
#> [5,] 4.877717 4.151272
#> [6,] 4.008152 4.095047
#> [7,] 3.875000 4.104418
#> [8,] 4.732337 4.927711
#> [9,] 5.105978 4.532798
#> [10,] 4.165761 4.184739
#> [11,] 4.472826 4.424364
#> [12,] 4.652174 4.751004
#> [13,] 4.652174 4.012048
#> [14,] 4.073370 4.127175
#> [15,] 4.019022 4.467202
#> [16,] 4.520380 4.461847
#> GTCAAGTCAATCGAAA-500.2.1 GTCAAGTGTGACTACT-500.2.1
#> [1,] 4.489726 4.395783
#> [2,] 4.236301 4.175182
#> [3,] 4.474886 4.545823
#> [4,] 4.466895 4.559611
#> [5,] 4.577626 4.209246
#> [6,] 4.426941 4.278994
#> [7,] 4.158676 4.048662
#> [8,] 5.063927 4.765612
#> [9,] 4.917808 4.823195
#> [10,] 4.482877 4.512571
#> [11,] 4.174658 4.494728
#> [12,] 4.477169 4.376318
#> [13,] 4.801370 4.054339
#> [14,] 4.355023 4.141119
#> [15,] 4.059361 4.424169
#> [16,] 4.394977 4.500406
#> GTCATTTTCTTAGCCC-500.2.1 GTCGTAATCTTCGGTC-500.2.1
#> [1,] 4.313808 4.733493
#> [2,] 4.245467 4.909964
#> [3,] 4.594142 4.244898
#> [4,] 4.722455 4.511405
#> [5,] 4.497908 4.374550
#> [6,] 4.298466 4.673469
#> [7,] 3.934449 3.903962
#> [8,] 4.923291 4.801921
#> [9,] 4.192469 4.378151
#> [10,] 4.315202 4.849940
#> [11,] 4.478382 4.148860
#> [12,] 4.315202 4.446579
#> [13,] 4.242678 4.685474
#> [14,] 4.451883 4.194478
#> [15,] 4.271967 3.925570
#> [16,] 4.047420 4.306122
#> GTCTCGTCACATGACT-500.2.1 GTCTCGTCATCCGTGG-500.2.1
#> [1,] 4.180887 4.447475
#> [2,] 3.984073 4.325595
#> [3,] 4.435722 4.548462
#> [4,] 4.680319 4.379571
#> [5,] 3.988623 4.203134
#> [6,] 4.188851 4.568775
#> [7,] 4.359499 4.240859
#> [8,] 5.026166 4.777713
#> [9,] 4.886234 4.612885
#> [10,] 4.400455 4.452699
#> [11,] 4.395904 4.045270
#> [12,] 4.122867 4.212420
#> [13,] 4.405006 4.370284
#> [14,] 4.771331 4.505514
#> [15,] 4.086462 4.179338
#> [16,] 4.084187 4.637261
#> GTCTTCGTCGGCGGTT-500.2.1 GTGCTTCAGTGCGATG-500.2.1
#> [1,] 4.437209 4.200262
#> [2,] 4.131163 4.269634
#> [3,] 4.339535 4.608639
#> [4,] 4.296744 4.287958
#> [5,] 4.808372 4.486911
#> [6,] 4.518140 4.545812
#> [7,] 4.203721 4.070681
#> [8,] 4.890233 4.844241
#> [9,] 4.645581 4.849476
#> [10,] 4.511628 4.409686
#> [11,] 4.418605 4.333770
#> [12,] 4.323721 4.433246
#> [13,] 4.375814 4.638743
#> [14,] 4.474419 4.221204
#> [15,] 4.511628 4.244764
#> [16,] 4.081860 4.523560
#> GTGCTTCGTCTCCATC-500.2.1 GTGTTAGGTTAGTGGG-500.2.1
#> [1,] 4.602981 4.509341
#> [2,] 4.215447 4.460177
#> [3,] 4.598916 4.218289
#> [4,] 4.257453 4.635202
#> [5,] 4.371274 4.636185
#> [6,] 4.256098 4.492625
#> [7,] 4.318428 4.046214
#> [8,] 4.846883 4.960669
#> [9,] 5.130081 4.473943
#> [10,] 4.165312 4.716814
#> [11,] 4.201897 4.632252
#> [12,] 4.378049 4.673550
#> [13,] 4.257453 4.348083
#> [14,] 4.508130 4.354966
#> [15,] 4.348238 4.280236
#> [16,] 4.399729 4.235005
#> GTTAAGCAGCCACGCT-500.2.1 GTTACAGGTCCGAACC-500.2.1
#> [1,] 4.420000 4.686869
#> [2,] 4.402353 4.208754
#> [3,] 4.245882 4.481481
#> [4,] 4.492941 4.235690
#> [5,] 4.620000 4.316498
#> [6,] 3.638824 4.498316
#> [7,] 4.423529 3.930415
#> [8,] 4.582353 4.943883
#> [9,] 4.922353 4.442200
#> [10,] 5.096471 4.436588
#> [11,] 4.331765 4.359147
#> [12,] 4.302353 4.478114
#> [13,] 4.140000 4.502806
#> [14,] 4.338824 4.234568
#> [15,] 5.162353 4.011223
#> [16,] 4.278824 4.212121
#> GTTCGGGGTCCAGTTA-500.2.1 TAAACCGCACCGTTGG-500.2.1
#> [1,] 4.631725 4.145811
#> [2,] 4.641708 4.630033
#> [3,] 4.313921 4.262242
#> [4,] 4.681087 4.479869
#> [5,] 4.376595 4.078346
#> [6,] 4.453688 3.990207
#> [7,] 4.064892 4.212187
#> [8,] 4.736550 4.616975
#> [9,] 4.480311 4.881393
#> [10,] 4.349972 4.690968
#> [11,] 4.575153 4.394995
#> [12,] 4.668885 4.405876
#> [13,] 4.520244 4.022851
#> [14,] 4.432058 4.317737
#> [15,] 4.242374 4.720348
#> [16,] 4.169717 4.189336
#> TAAACCGGTCAACATC-500.2.1 TAAACCGTCGTTGCCT-500.2.1
#> [1,] 4.473054 4.360399
#> [2,] 4.553293 4.029915
#> [3,] 4.838323 4.905983
#> [4,] 4.457485 4.269231
#> [5,] 4.579641 4.646724
#> [6,] 4.183234 4.162393
#> [7,] 4.100599 4.024217
#> [8,] 4.831138 5.007123
#> [9,] 4.441916 4.388889
#> [10,] 4.080240 4.421652
#> [11,] 4.597605 4.075499
#> [12,] 4.580838 4.283476
#> [13,] 4.518563 4.930199
#> [14,] 4.354491 4.324786
#> [15,] 4.174850 3.887464
#> [16,] 4.633533 4.240741
#> TAAGTGCGTACCATCA-500.2.1 TACAGTGAGATGGGTC-500.2.1
#> [1,] 4.631183 4.468750
#> [2,] 4.335484 4.584821
#> [3,] 4.559140 4.671875
#> [4,] 4.387097 4.572545
#> [5,] 4.355914 4.178571
#> [6,] 4.084946 4.197545
#> [7,] 4.082796 4.213170
#> [8,] 4.740860 4.543527
#> [9,] 4.512903 4.960938
#> [10,] 4.188172 4.897321
#> [11,] 4.354839 4.685268
#> [12,] 4.506452 4.207589
#> [13,] 4.649462 4.328125
#> [14,] 4.477419 4.518973
#> [15,] 3.915054 4.954241
#> [16,] 4.482796 4.332589
#> TACCTTAAGAAGGTGA-500.2.1 TACCTTATCCTAGAAC-500.2.1
#> [1,] 4.355359 4.259511
#> [2,] 4.124899 4.618207
#> [3,] 4.506849 4.610054
#> [4,] 4.555197 4.468750
#> [5,] 4.216761 4.754076
#> [6,] 4.618050 4.283967
#> [7,] 3.968574 4.173913
#> [8,] 5.097502 5.065217
#> [9,] 5.656728 4.729620
#> [10,] 4.502015 4.573370
#> [11,] 4.522160 4.524457
#> [12,] 4.475423 4.528533
#> [13,] 3.787268 4.194293
#> [14,] 4.409347 4.404891
#> [15,] 4.292506 4.099185
#> [16,] 4.208703 4.616848
#> TACGGATGTGAAATCA-500.2.1 TACGGGCCACGAAGCA-500.2.1
#> [1,] 4.315877 4.454418
#> [2,] 4.261014 4.500701
#> [3,] 4.496259 4.691445
#> [4,] 3.889443 4.451613
#> [5,] 4.683292 4.371669
#> [6,] 4.572735 4.189341
#> [7,] 4.236076 4.037868
#> [8,] 5.122195 4.827489
#> [9,] 4.768080 4.461431
#> [10,] 4.350790 4.356241
#> [11,] 4.487947 4.279102
#> [12,] 4.418953 4.661992
#> [13,] 4.438903 4.611501
#> [14,] 4.446384 4.855540
#> [15,] 4.137157 4.043478
#> [16,] 4.560266 4.723703
#> TACGGTAAGATAGTCA-500.2.1 TACTCGCAGGAATCGC-500.2.1
#> [1,] 4.593530 4.432044
#> [2,] 4.389592 4.255249
#> [3,] 4.893108 4.593370
#> [4,] 4.492264 4.183425
#> [5,] 4.549930 4.773481
#> [6,] 4.493671 4.130387
#> [7,] 4.364276 4.146961
#> [8,] 4.776371 5.169061
#> [9,] 4.510549 4.662983
#> [10,] 4.333333 4.302762
#> [11,] 4.229255 4.272928
#> [12,] 4.786217 4.510497
#> [13,] 4.399437 4.612155
#> [14,] 4.260197 4.214365
#> [15,] 4.112518 4.137017
#> [16,] 4.233474 4.495028
#> TACTTACCAAGTCTAC-500.2.1 TAGACCAAGAAAGTGG-500.2.1
#> [1,] 4.667112 4.566970
#> [2,] 4.283422 4.431730
#> [3,] 4.586898 4.501951
#> [4,] 4.239305 4.625488
#> [5,] 4.375668 4.712614
#> [6,] 4.370321 4.420026
#> [7,] 4.155080 3.641092
#> [8,] 4.990642 4.884265
#> [9,] 4.094920 4.925878
#> [10,] 4.758021 4.908973
#> [11,] 4.351604 4.091027
#> [12,] 4.635027 4.145644
#> [13,] 4.628342 4.176853
#> [14,] 4.118984 4.167750
#> [15,] 4.036096 4.439532
#> [16,] 4.224599 3.880364
#> TAGAGCTAGAGAACAG-500.2.1 TAGTGGTGTCATTAGC-500.2.1
#> [1,] 4.529748 4.430481
#> [2,] 4.208238 4.542781
#> [3,] 4.794050 4.521390
#> [4,] 4.183066 4.812834
#> [5,] 4.696796 4.509358
#> [6,] 4.256293 4.248663
#> [7,] 4.498856 4.259358
#> [8,] 4.735698 4.703209
#> [9,] 4.911899 4.574866
#> [10,] 4.422197 4.352941
#> [11,] 4.117849 4.338235
#> [12,] 4.504577 4.340909
#> [13,] 4.320366 4.318182
#> [14,] 4.384439 4.350267
#> [15,] 4.220824 4.204545
#> [16,] 4.410755 4.508021
#> TATCAGGAGAAGCCCA-500.2.1 TATCAGGTCCGAAGAG-500.2.1
#> [1,] 4.018868 4.383880
#> [2,] 4.163853 3.979508
#> [3,] 4.750745 4.573770
#> [4,] 4.413108 4.938525
#> [5,] 4.852036 4.438525
#> [6,] 4.867925 4.178962
#> [7,] 4.441907 4.449454
#> [8,] 4.986097 4.842896
#> [9,] 4.367428 4.812842
#> [10,] 4.127110 4.419399
#> [11,] 3.745780 4.286885
#> [12,] 4.129096 4.625683
#> [13,] 5.008937 4.534153
#> [14,] 4.423039 4.289617
#> [15,] 4.124131 4.445355
#> [16,] 5.071500 4.170765
#> TATCTCAAGTACGCCC-500.2.1 TATCTCACAGTCACTA-500.2.1
#> [1,] 4.473445 4.322845
#> [2,] 4.211684 4.188098
#> [3,] 4.483308 4.550616
#> [4,] 4.204856 4.646375
#> [5,] 4.465857 4.552668
#> [6,] 4.638088 4.455540
#> [7,] 4.115326 3.980164
#> [8,] 4.893020 4.771546
#> [9,] 4.506829 5.126539
#> [10,] 4.015933 4.805062
#> [11,] 4.364947 4.316005
#> [12,] 4.369499 4.145691
#> [13,] 4.305008 4.580027
#> [14,] 4.683612 4.346785
#> [15,] 4.188923 3.857729
#> [16,] 4.526555 4.342681
#> TATGCCCGTTGGTTTG-500.2.1 TATTACCTCATTCACT-500.2.1
#> [1,] 4.538760 4.224644
#> [2,] 4.380952 4.441744
#> [3,] 4.640642 4.617770
#> [4,] 4.282946 4.423303
#> [5,] 4.623477 4.477787
#> [6,] 4.375969 4.345348
#> [7,] 3.904208 4.310981
#> [8,] 4.981174 4.758592
#> [9,] 4.564784 4.861693
#> [10,] 4.305094 4.730930
#> [11,] 4.183832 4.544007
#> [12,] 4.254153 4.503772
#> [13,] 4.501661 4.271584
#> [14,] 4.167220 4.502096
#> [15,] 4.062016 4.850796
#> [16,] 4.435216 4.421626
#> TCAACGATCTAGAGTC-500.2.1 TCACGAACACCACGTG-500.2.1
#> [1,] 4.443575 4.749642
#> [2,] 4.410056 3.859800
#> [3,] 4.540782 4.061516
#> [4,] 4.627933 4.347639
#> [5,] 4.576536 4.653791
#> [6,] 3.889385 3.834049
#> [7,] 4.194413 4.181688
#> [8,] 5.011173 4.795422
#> [9,] 4.738547 4.653791
#> [10,] 4.351955 3.945637
#> [11,] 4.563128 4.278970
#> [12,] 4.233520 4.243205
#> [13,] 4.223464 5.014306
#> [14,] 4.339665 4.276109
#> [15,] 4.634637 3.659514
#> [16,] 4.349721 4.353362
#> TCAGATGCAAACTGTC-500.2.1 TCAGCAAAGGAATGGA-500.2.1
#> [1,] 4.406657 4.422535
#> [2,] 4.382055 4.407170
#> [3,] 4.720695 4.734955
#> [4,] 4.788712 4.367478
#> [5,] 4.217077 4.539052
#> [6,] 4.128799 4.582586
#> [7,] 4.322721 3.952625
#> [8,] 4.810420 4.874520
#> [9,] 4.733719 4.573624
#> [10,] 3.971056 4.622279
#> [11,] 4.493488 4.421255
#> [12,] 4.461650 4.811780
#> [13,] 4.463097 4.258643
#> [14,] 4.395080 4.254802
#> [15,] 4.199711 4.175416
#> [16,] 4.461650 4.377721
#> TCAGGATGTGCTCTTC-500.2.1 TCAGGTACACCAGGTC-500.2.1
#> [1,] 4.486239 4.313003
#> [2,] 4.346003 4.420023
#> [3,] 4.437746 4.684695
#> [4,] 4.787680 4.475259
#> [5,] 4.339450 4.454545
#> [6,] 4.171691 4.424626
#> [7,] 4.294889 4.216341
#> [8,] 4.441678 4.857307
#> [9,] 4.862385 4.327963
#> [10,] 4.480996 4.535098
#> [11,] 4.458716 4.540852
#> [12,] 4.487549 4.387802
#> [13,] 4.462647 4.202532
#> [14,] 4.294889 4.207135
#> [15,] 4.640891 4.410817
#> [16,] 4.281782 4.293441
#> TCATTACTCACGCATA-500.2.1 TCATTTGCATACCATG-500.2.1
#> [1,] 4.680217 4.428937
#> [2,] 4.146341 4.393086
#> [3,] 4.173442 3.979513
#> [4,] 4.101626 4.014085
#> [5,] 4.685637 4.268886
#> [6,] 4.177507 4.763124
#> [7,] 3.813008 4.090909
#> [8,] 4.788618 4.729834
#> [9,] 4.810298 4.167734
#> [10,] 4.033875 4.425096
#> [11,] 4.356369 4.125480
#> [12,] 4.478320 4.961588
#> [13,] 4.735772 4.161332
#> [14,] 4.124661 4.211268
#> [15,] 3.887534 3.673496
#> [16,] 4.414634 4.257362
#> TCGAGGCGTGCGCTTG-500.2.1 TCGCGAGCACTGCCAG-500.2.1
#> [1,] 4.370615 4.793132
#> [2,] 4.058901 4.114740
#> [3,] 4.434811 4.510050
#> [4,] 4.634679 4.315745
#> [5,] 4.280609 4.757119
#> [6,] 4.554600 4.355109
#> [7,] 3.953011 4.448074
#> [8,] 5.052283 4.970687
#> [9,] 5.471873 4.735343
#> [10,] 4.785572 4.420436
#> [11,] 4.465255 4.533501
#> [12,] 4.136334 4.530151
#> [13,] 4.227664 4.510050
#> [14,] 4.112508 4.762982
#> [15,] 4.144275 4.176717
#> [16,] 4.356717 4.572864
#> TCGCGTTTCATAACCG-500.2.1 TCGCGTTTCGTTACAG-500.2.1
#> [1,] 4.277778 4.546734
#> [2,] 3.961988 4.324623
#> [3,] 4.350877 4.438191
#> [4,] 4.762183 3.973869
#> [5,] 4.174464 4.519598
#> [6,] 4.230019 3.965829
#> [7,] 4.083821 4.201005
#> [8,] 5.013645 5.076382
#> [9,] 4.952242 4.762814
#> [10,] 4.532164 4.267337
#> [11,] 4.340156 4.235176
#> [12,] 4.384990 4.401005
#> [13,] 4.207602 4.369849
#> [14,] 4.273879 4.064322
#> [15,] 4.575049 4.251256
#> [16,] 4.212476 4.481407
#> TCGGTAACATAAAGGT-500.2.1 TCGTACCTCAATAAGG-500.2.1
#> [1,] 4.603699 4.009459
#> [2,] 4.825627 4.189189
#> [3,] 4.080581 4.440541
#> [4,] 4.507266 3.929730
#> [5,] 4.313078 4.529730
#> [6,] 4.331572 4.631081
#> [7,] 4.188904 4.075676
#> [8,] 4.910172 4.508108
#> [9,] 4.681638 4.550000
#> [10,] 4.321004 3.847297
#> [11,] 4.354029 4.183784
#> [12,] 4.527081 4.421622
#> [13,] 4.659181 4.090541
#> [14,] 4.305152 4.855405
#> [15,] 4.254954 4.106757
#> [16,] 4.108322 4.359459
#> TCGTAGATCGCCATAA-500.2.1 TCTATTGAGCCAGTAG-500.2.1
#> [1,] 4.448310 4.170601
#> [2,] 4.336978 4.453863
#> [3,] 4.867793 4.039700
#> [4,] 4.188867 4.350858
#> [5,] 4.482107 4.231760
#> [6,] 4.274354 4.106223
#> [7,] 4.316103 3.817597
#> [8,] 4.788270 4.697425
#> [9,] 4.446322 4.793991
#> [10,] 4.407555 4.585837
#> [11,] 4.492048 4.344421
#> [12,] 4.532803 4.203863
#> [13,] 3.998012 4.724249
#> [14,] 4.281312 4.724249
#> [15,] 3.986083 4.372318
#> [16,] 4.433400 4.109442
#> TCTTTCCCAGTAACGG-500.2.1 TCTTTCCGTTATCCGA-500.2.1
#> [1,] 4.313821 4.524450
#> [2,] 4.040650 4.484108
#> [3,] 4.447967 4.411980
#> [4,] 4.395935 4.480440
#> [5,] 4.386179 4.761614
#> [6,] 3.761789 4.176039
#> [7,] 4.260163 4.396088
#> [8,] 4.522764 4.746944
#> [9,] 4.341463 4.457213
#> [10,] 3.972358 4.135697
#> [11,] 4.026829 4.385086
#> [12,] 4.315447 4.641809
#> [13,] 4.551220 4.327628
#> [14,] 4.160163 4.144254
#> [15,] 4.109756 4.398533
#> [16,] 4.239024 4.453545
#> TCTTTCCTCAACTCTT-500.2.1 TGACAACGTTCGCGAC-500.2.1
#> [1,] 4.301759 4.451967
#> [2,] 4.255751 4.023788
#> [3,] 4.805142 4.698079
#> [4,] 4.774019 4.205855
#> [5,] 4.202977 4.596523
#> [6,] 4.381597 4.713632
#> [7,] 4.028417 4.271729
#> [8,] 4.917456 4.908509
#> [9,] 4.921516 4.645929
#> [10,] 4.472260 4.427264
#> [11,] 4.055480 4.826167
#> [12,] 4.561570 4.477585
#> [13,] 4.235453 4.195791
#> [14,] 4.433018 4.580970
#> [15,] 4.369418 4.467521
#> [16,] 4.266576 4.389753
#> TGACGGCAGGTTCCTA-500.2.1 TGACGGCTCCATTCTA-500.2.1
#> [1,] 4.535885 4.237482
#> [2,] 4.257177 4.071531
#> [3,] 4.435407 4.278970
#> [4,] 4.361244 4.598712
#> [5,] 4.730861 4.844778
#> [6,] 4.265550 4.874106
#> [7,] 4.058612 3.963519
#> [8,] 4.791866 4.773247
#> [9,] 4.651914 4.695279
#> [10,] 4.355263 4.643062
#> [11,] 4.333732 4.476395
#> [12,] 4.327751 4.341917
#> [13,] 4.892344 4.366237
#> [14,] 4.232057 4.685980
#> [15,] 4.223684 4.463519
#> [16,] 4.344498 4.417740
#> TGACTAGAGTATCGAA-500.2.1 TGACTAGTCTACTATC-500.2.1
#> [1,] 4.546610 4.143959
#> [2,] 4.353107 4.256213
#> [3,] 4.271186 4.651243
#> [4,] 4.548023 4.642674
#> [5,] 4.632768 4.579263
#> [6,] 4.162429 4.135390
#> [7,] 4.104520 4.497858
#> [8,] 4.830508 4.413882
#> [9,] 5.038136 4.804627
#> [10,] 4.161017 4.271637
#> [11,] 4.218927 4.475578
#> [12,] 4.577684 4.496144
#> [13,] 4.607345 4.305056
#> [14,] 4.512712 4.431877
#> [15,] 4.166667 4.522708
#> [16,] 4.199153 4.267352
#> TGAGAGGTCCACGACG-500.2.1 TGAGCATCACTATCTT-500.2.1
#> [1,] 4.219883 4.541223
#> [2,] 4.438596 4.251330
#> [3,] 4.528655 4.492021
#> [4,] 4.394152 4.284574
#> [5,] 4.236257 4.632979
#> [6,] 4.464327 4.252660
#> [7,] 3.941520 4.147606
#> [8,] 4.810526 4.940160
#> [9,] 5.405848 4.550532
#> [10,] 4.821053 4.007979
#> [11,] 4.113450 4.167553
#> [12,] 4.125146 4.651596
#> [13,] 4.412865 4.672872
#> [14,] 4.409357 4.445479
#> [15,] 4.504094 4.341755
#> [16,] 4.437427 4.454787
#> TGAGCCGCAAACGTGG-500.2.1 TGAGCCGCATTAGCCA-500.2.1
#> [1,] 4.791630 4.383673
#> [2,] 4.959895 3.972789
#> [3,] 4.136879 4.619048
#> [4,] 4.158675 4.419048
#> [5,] 4.039233 4.600000
#> [6,] 4.897995 4.398639
#> [7,] 4.141238 4.088435
#> [8,] 4.531822 5.450340
#> [9,] 3.988666 4.940136
#> [10,] 4.523104 3.974150
#> [11,] 4.398431 4.370068
#> [12,] 4.545772 4.069388
#> [13,] 4.092415 4.148299
#> [14,] 4.283348 4.715646
#> [15,] 3.820401 4.250340
#> [16,] 4.253705 4.544218
#> TGAGGGACAACGATCT-500.2.1 TGATTTCGTGACTACT-500.2.1
#> [1,] 4.513612 4.169371
#> [2,] 4.149728 4.163286
#> [3,] 4.554446 3.984787
#> [4,] 4.390200 4.085193
#> [5,] 4.594374 4.317444
#> [6,] 4.403811 4.850913
#> [7,] 4.295826 4.138945
#> [8,] 4.813067 4.585193
#> [9,] 4.632486 4.472617
#> [10,] 4.345735 4.240365
#> [11,] 4.715971 4.272819
#> [12,] 4.528131 4.236308
#> [13,] 4.042650 4.159229
#> [14,] 4.527223 4.900609
#> [15,] 4.352087 4.050710
#> [16,] 4.441016 4.741379
#> TGCCCTATCGTAGGAG-500.2.1 TGCGTGGGTGGCTCCA-500.2.1
#> [1,] 4.410832 4.505945
#> [2,] 4.368560 4.644650
#> [3,] 4.558785 4.528402
#> [4,] 4.515192 4.220608
#> [5,] 4.627477 4.648613
#> [6,] 4.299868 4.361955
#> [7,] 4.245707 4.373844
#> [8,] 4.885073 4.931308
#> [9,] 4.437252 4.784676
#> [10,] 4.210040 4.712021
#> [11,] 3.949802 4.260238
#> [12,] 4.404227 4.278732
#> [13,] 4.297226 4.384412
#> [14,] 4.302510 4.371202
#> [15,] 4.137384 4.540291
#> [16,] 4.480845 4.309115
#> TGGACGCCATTGCGGC-500.2.1 TGTATTCAGCCCGAAA-500.2.1
#> [1,] 4.920000 4.459413
#> [2,] 4.304828 4.452936
#> [3,] 4.413793 4.377807
#> [4,] 4.147586 4.533679
#> [5,] 4.182069 4.543178
#> [6,] 4.460690 4.267271
#> [7,] 4.351724 4.123489
#> [8,] 4.579310 4.847150
#> [9,] 4.900690 4.419257
#> [10,] 4.393103 4.506908
#> [11,] 4.397241 4.392487
#> [12,] 4.484138 4.553972
#> [13,] 4.455172 4.261658
#> [14,] 4.313103 4.503454
#> [15,] 4.096552 4.224525
#> [16,] 4.311724 4.295337
#> TGTGGTAGTAAATACG-500.2.1 TGTGGTAGTAAGTAGT-500.2.1
#> [1,] 4.364331 4.463504
#> [2,] 4.144586 4.285584
#> [3,] 4.477707 4.442518
#> [4,] 4.533758 4.096715
#> [5,] 4.501911 4.946168
#> [6,] 4.293631 4.743613
#> [7,] 3.985350 4.286496
#> [8,] 4.879618 5.311131
#> [9,] 5.033758 4.691606
#> [10,] 4.466879 4.479927
#> [11,] 4.245223 4.654197
#> [12,] 4.261783 4.402372
#> [13,] 4.551592 4.130474
#> [14,] 4.151592 4.384124
#> [15,] 4.005096 4.343066
#> [16,] 4.424841 4.466241
#> TTAACTCAGGACGAAA-500.2.1 TTAGGACAGAAGAAGC-500.2.1
#> [1,] 4.450126 4.584699
#> [2,] 4.362951 4.109290
#> [3,] 4.512992 4.222222
#> [4,] 4.568315 4.212204
#> [5,] 4.510478 4.756831
#> [6,] 4.433361 4.102914
#> [7,] 4.388935 4.432605
#> [8,] 4.930427 4.472678
#> [9,] 4.660520 4.168488
#> [10,] 4.450964 4.116576
#> [11,] 4.434199 3.966302
#> [12,] 4.357921 4.220401
#> [13,] 4.254820 4.526412
#> [14,] 4.329422 4.313297
#> [15,] 4.198659 4.043716
#> [16,] 4.324392 4.243169
#> TTAGGACGTGCAGTAG-500.2.1 TTAGGACGTTTACTCT-500.2.1
#> [1,] 4.416298 4.515759
#> [2,] 4.350753 4.431710
#> [3,] 4.523472 4.571156
#> [4,] 4.731621 4.441261
#> [5,] 4.230292 4.469914
#> [6,] 4.240035 4.286533
#> [7,] 4.131975 3.900669
#> [8,] 4.771479 4.937918
#> [9,] 4.815766 4.897803
#> [10,] 4.560673 4.160458
#> [11,] 4.329495 4.282713
#> [12,] 4.469442 4.607450
#> [13,] 4.382640 4.412607
#> [14,] 4.649247 4.322827
#> [15,] 4.232950 4.156638
#> [16,] 4.410097 4.505253
#> TTCGAAGCACCAGGCT-500.2.1 TTCTACACAGACGTAG-500.2.1
#> [1,] 4.450284 4.068637
#> [2,] 4.588068 4.455672
#> [3,] 4.822443 4.324118
#> [4,] 4.836648 4.452812
#> [5,] 4.346591 4.561487
#> [6,] 4.340909 4.411821
#> [7,] 3.875000 4.224023
#> [8,] 5.178977 4.594852
#> [9,] 4.390625 4.697807
#> [10,] 4.561080 4.259295
#> [11,] 4.710227 4.531935
#> [12,] 4.700284 4.318398
#> [13,] 4.190341 4.349857
#> [14,] 4.482955 4.206864
#> [15,] 4.376420 4.256435
#> [16,] 4.009943 4.363203
#> TTCTTAGCATCCCATC-500.2.1 TTGAACGGTCACCCAG-500.2.1
#> [1,] 4.537010 4.721344
#> [2,] 4.298984 4.440711
#> [3,] 4.410740 4.503953
#> [4,] 4.375907 4.201581
#> [5,] 4.708273 4.814229
#> [6,] 4.107402 3.937747
#> [7,] 3.793904 4.202569
#> [8,] 4.751814 4.948617
#> [9,] 4.766328 4.460474
#> [10,] 4.429608 4.469368
#> [11,] 4.136430 4.250988
#> [12,] 4.343977 4.658103
#> [13,] 4.934688 4.666996
#> [14,] 4.275762 4.282609
#> [15,] 4.066763 4.332016
#> [16,] 4.612482 4.566206
#> TTGAACGGTGCCTGGT-500.2.1 TTGACTTCAACGATCT-500.2.1
#> [1,] 4.811178 4.464429
#> [2,] 4.361782 4.367234
#> [3,] 4.453927 4.770040
#> [4,] 4.324773 4.740982
#> [5,] 4.749245 4.416834
#> [6,] 4.379909 4.275551
#> [7,] 4.141994 3.872745
#> [8,] 5.006042 4.948397
#> [9,] 4.785498 4.951403
#> [10,] 4.204683 4.684870
#> [11,] 4.217523 4.285571
#> [12,] 4.436556 4.305611
#> [13,] 4.583082 4.339679
#> [14,] 4.253776 4.124248
#> [15,] 3.926737 4.140782
#> [16,] 4.625378 4.309619
#> TTGCCGTAGAACAACT-500.2.1 TTGGCAACAGGAATCG-500.2.1
#> [1,] 4.677911 4.635831
#> [2,] 4.577802 4.380562
#> [3,] 4.319913 4.451991
#> [4,] 4.658324 4.392272
#> [5,] 4.594124 4.505855
#> [6,] 4.447225 4.548009
#> [7,] 3.908596 4.337237
#> [8,] 5.115343 4.847775
#> [9,] 4.602829 4.752927
#> [10,] 4.738847 4.257611
#> [11,] 4.145811 4.336066
#> [12,] 4.533188 4.497658
#> [13,] 4.121872 4.340749
#> [14,] 4.238303 4.269321
#> [15,] 4.371055 4.314988
#> [16,] 4.253536 4.213115
#> TTGGCAAGTGCTGTAT-500.2.1 TTTATGCGTGCAGTAG-500.2.1
#> [1,] 4.607383 3.875000
#> [2,] 4.253356 4.485372
#> [3,] 4.520134 4.263298
#> [4,] 4.145973 4.238032
#> [5,] 4.776846 4.347074
#> [6,] 4.568792 4.682181
#> [7,] 4.268456 3.909574
#> [8,] 4.612416 5.184840
#> [9,] 4.757550 4.635638
#> [10,] 4.346477 4.297872
#> [11,] 4.744128 4.041223
#> [12,] 4.606544 4.538564
#> [13,] 3.955537 4.307181
#> [14,] 4.478188 4.914894
#> [15,] 4.252517 4.309840
#> [16,] 4.141779 4.674202
#> TTTCCTCAGTCTCAAC-500.2.1 TTTGCGCGTCGCCATG-500.2.1
#> [1,] 4.376847 4.494008
#> [2,] 4.253695 4.146471
#> [3,] 4.498768 4.544607
#> [4,] 4.652709 4.360852
#> [5,] 4.178571 4.568575
#> [6,] 4.350985 4.302264
#> [7,] 4.479064 3.846871
#> [8,] 4.869458 4.925433
#> [9,] 4.688424 4.868176
#> [10,] 4.322660 4.307590
#> [11,] 4.513547 4.262317
#> [12,] 4.233990 4.226365
#> [13,] 4.113300 4.555260
#> [14,] 4.399015 4.540613
#> [15,] 4.093596 4.278296
#> [16,] 4.251232 4.720373
#> AAACCTGTCGGTGTTA-500.2.2 AAAGATGCAGTAACGG-500.2.2
#> [1,] 4.459538 4.148668
#> [2,] 4.193642 4.363254
#> [3,] 4.727360 4.660589
#> [4,] 4.202312 4.656381
#> [5,] 4.665703 4.680224
#> [6,] 4.302505 4.166900
#> [7,] 4.288054 4.126227
#> [8,] 4.646435 4.918654
#> [9,] 4.526975 4.525947
#> [10,] 4.272640 3.967742
#> [11,] 4.603083 4.056101
#> [12,] 4.599229 4.291725
#> [13,] 4.180154 4.284712
#> [14,] 4.311175 4.490884
#> [15,] 4.306358 4.405330
#> [16,] 4.398844 4.406732
#> AAAGATGCAGTCGTGC-500.2.2 AACGTTGTCGTTGACA-500.2.2
#> [1,] 4.638128 4.399103
#> [2,] 4.450913 4.395740
#> [3,] 4.457763 4.495516
#> [4,] 4.437215 4.541480
#> [5,] 4.382420 4.224215
#> [6,] 4.321918 4.264574
#> [7,] 4.175799 4.060538
#> [8,] 4.836758 4.797085
#> [9,] 4.831050 5.084081
#> [10,] 4.272831 4.158072
#> [11,] 4.216895 4.270179
#> [12,] 4.808219 4.456278
#> [13,] 4.423516 4.339686
#> [14,] 4.488584 4.520179
#> [15,] 4.240868 4.137892
#> [16,] 4.655251 4.439462
#> AACTCAGGTGCAGGTA-500.2.2 AACTCAGTCACATACG-500.2.2
#> [1,] 4.294045 4.334739
#> [2,] 4.461538 5.053963
#> [3,] 4.616625 4.623103
#> [4,] 4.248139 4.186341
#> [5,] 4.817618 4.061551
#> [6,] 4.017370 4.635750
#> [7,] 4.088089 4.091062
#> [8,] 5.088089 5.101180
#> [9,] 4.362283 4.526981
#> [10,] 4.387097 4.211636
#> [11,] 4.130273 4.505902
#> [12,] 4.665012 4.903035
#> [13,] 4.182382 4.371838
#> [14,] 4.380893 4.094435
#> [15,] 4.166253 4.094435
#> [16,] 4.370968 4.263912
#> AACTCCCGTCAAGCGA-500.2.2 AACTCTTGTAAGAGAG-500.2.2
#> [1,] 4.400249 4.627054
#> [2,] 4.238658 4.240202
#> [3,] 4.686762 4.361568
#> [4,] 4.238658 4.381795
#> [5,] 4.761342 4.408976
#> [6,] 4.766936 4.658028
#> [7,] 4.249223 4.064475
#> [8,] 4.618397 4.768015
#> [9,] 4.692977 4.682048
#> [10,] 4.309509 4.486726
#> [11,] 4.814792 4.589760
#> [12,] 4.351150 4.545512
#> [13,] 4.075202 3.832491
#> [14,] 4.420137 4.321113
#> [15,] 4.351771 4.347029
#> [16,] 4.708515 4.516435
#> AACTCTTGTAGGAGTC-500.2.2 AACTTTCAGATGCGAC-500.2.2
#> [1,] 4.218053 4.392157
#> [2,] 4.396411 4.245098
#> [3,] 4.586188 4.649510
#> [4,] 4.411637 4.465686
#> [5,] 4.634584 5.109069
#> [6,] 4.498097 4.424020
#> [7,] 4.102229 4.219363
#> [8,] 5.016857 5.145833
#> [9,] 4.735726 4.709559
#> [10,] 4.676998 4.230392
#> [11,] 4.495922 4.513480
#> [12,] 4.465470 4.427696
#> [13,] 4.307776 4.714461
#> [14,] 4.247417 4.164216
#> [15,] 4.286025 3.844363
#> [16,] 4.590538 4.399510
#> AACTTTCGTCAAGCGA-500.2.2 AAGACCTTCCAGTATG-500.2.2
#> [1,] 4.426637 4.555466
#> [2,] 4.654063 3.991961
#> [3,] 4.494921 4.437299
#> [4,] 4.784989 4.174437
#> [5,] 4.520316 4.462219
#> [6,] 4.199774 4.481511
#> [7,] 4.257336 4.175241
#> [8,] 5.102709 4.747588
#> [9,] 4.946953 4.459003
#> [10,] 4.616817 4.258842
#> [11,] 4.469526 4.143891
#> [12,] 4.195824 4.346463
#> [13,] 4.389391 4.793408
#> [14,] 4.357223 4.293408
#> [15,] 4.521445 4.006431
#> [16,] 4.235327 4.749196
#> AAGCCGCCACACCGAC-500.2.2 AAGGAGCCAAGCCGCT-500.2.2
#> [1,] 4.288981 4.247675
#> [2,] 4.305613 4.232460
#> [3,] 4.516632 4.505495
#> [4,] 4.299376 4.479290
#> [5,] 4.640333 4.698225
#> [6,] 4.534304 4.643280
#> [7,] 4.098753 4.163990
#> [8,] 4.603950 4.752325
#> [9,] 4.350312 4.524091
#> [10,] 4.498960 4.379544
#> [11,] 4.519751 4.584108
#> [12,] 4.487526 4.395604
#> [13,] 4.198545 4.402367
#> [14,] 4.328482 4.413356
#> [15,] 4.575884 4.370245
#> [16,] 4.505198 4.595097
#> AAGGTTCAGCGATATA-500.2.2 AAGGTTCAGCTAGTCT-500.2.2
#> [1,] 4.742351 4.381926
#> [2,] 4.123188 4.124670
#> [3,] 4.363124 4.363456
#> [4,] 4.028986 4.237467
#> [5,] 4.338969 4.607520
#> [6,] 4.846216 4.704485
#> [7,] 3.744767 4.108179
#> [8,] 4.767311 4.963720
#> [9,] 4.484702 4.615435
#> [10,] 4.229469 4.500000
#> [11,] 4.214976 4.655673
#> [12,] 4.229469 4.342348
#> [13,] 4.530596 4.015172
#> [14,] 4.454106 4.308047
#> [15,] 4.086151 4.503958
#> [16,] 4.657810 4.257256
#> AAGGTTCGTTAAGTAG-500.2.2 AATCCAGGTAGGCTGA-500.2.2
#> [1,] 4.007101 4.525203
#> [2,] 4.584615 4.295935
#> [3,] 4.325444 4.567480
#> [4,] 4.396450 4.660163
#> [5,] 4.155030 4.656098
#> [6,] 3.763314 4.460163
#> [7,] 4.281657 4.247154
#> [8,] 4.872189 4.905691
#> [9,] 4.971598 4.671545
#> [10,] 4.342012 4.365854
#> [11,] 4.384615 4.575610
#> [12,] 4.550296 4.884553
#> [13,] 4.344379 4.245528
#> [14,] 4.305325 4.451220
#> [15,] 4.566864 4.104878
#> [16,] 4.162130 4.143089
#> ACACCAATCCACGACG-500.2.2 ACACTGATCTGTCCGT-500.2.2
#> [1,] 4.549949 4.463270
#> [2,] 4.530381 4.183649
#> [3,] 4.628218 4.270142
#> [4,] 4.211123 4.264218
#> [5,] 4.545829 4.495261
#> [6,] 4.687951 4.463270
#> [7,] 4.334706 4.246445
#> [8,] 4.761071 4.501185
#> [9,] 4.761071 4.758294
#> [10,] 4.710608 4.008294
#> [11,] 4.306900 4.248815
#> [12,] 4.459320 4.577014
#> [13,] 4.260556 4.702607
#> [14,] 4.154480 4.772512
#> [15,] 4.047374 4.101896
#> [16,] 4.446962 4.361374
#> ACAGCCGGTTGAGTTC-500.2.2 ACAGCTATCCACTGGG-500.2.2
#> [1,] 4.679907 4.370656
#> [2,] 4.134346 4.445946
#> [3,] 4.644860 4.399614
#> [4,] 4.155374 4.424710
#> [5,] 4.589953 4.532819
#> [6,] 4.370327 4.285714
#> [7,] 4.018692 4.160232
#> [8,] 5.101636 4.762548
#> [9,] 4.817757 4.486486
#> [10,] 4.515187 4.370656
#> [11,] 4.324766 4.385135
#> [12,] 4.385514 4.439189
#> [13,] 4.281542 4.030888
#> [14,] 4.336449 4.531853
#> [15,] 4.371495 4.217181
#> [16,] 4.580607 4.264479
#> ACATACGGTGCAGTAG-500.2.2 ACATCAGAGAAGCCCA-500.2.2
#> [1,] 4.101631 4.184388
#> [2,] 4.444793 4.187079
#> [3,] 4.640527 4.753701
#> [4,] 4.555834 4.253028
#> [5,] 4.476161 4.257066
#> [6,] 4.092221 4.254374
#> [7,] 3.868256 4.157470
#> [8,] 4.969887 4.606999
#> [9,] 4.548306 4.716016
#> [10,] 3.894605 4.109017
#> [11,] 4.383940 4.327052
#> [12,] 3.984316 4.340511
#> [13,] 4.239649 4.320323
#> [14,] 4.208908 4.008075
#> [15,] 4.427854 4.584118
#> [16,] 4.604141 4.430686
#> ACATGGTCAGTAACGG-500.2.2 ACATGGTGTAGTAGTA-500.2.2
#> [1,] 4.380440 4.465845
#> [2,] 3.988735 4.175608
#> [3,] 4.397849 4.344219
#> [4,] 4.773682 4.409863
#> [5,] 4.156170 4.324558
#> [6,] 4.410650 4.587804
#> [7,] 3.824373 4.228924
#> [8,] 4.944700 4.860380
#> [9,] 5.631848 4.796401
#> [10,] 4.765489 4.351216
#> [11,] 4.265233 4.361879
#> [12,] 4.114695 4.424525
#> [13,] 3.951357 4.214595
#> [14,] 4.106503 4.592469
#> [15,] 4.170507 4.270910
#> [16,] 4.287250 4.510163
#> ACATGGTTCCGATATG-500.2.2 ACCCACTAGTTGCAGG-500.2.2
#> [1,] 4.647210 4.733333
#> [2,] 3.981974 4.448101
#> [3,] 4.377682 4.488608
#> [4,] 4.145923 4.097046
#> [5,] 4.883262 4.524895
#> [6,] 4.922747 4.112236
#> [7,] 4.065236 4.098734
#> [8,] 4.617167 4.633755
#> [9,] 4.692704 4.390717
#> [10,] 4.543348 4.123207
#> [11,] 4.739914 3.943460
#> [12,] 4.443777 4.470886
#> [13,] 4.001717 4.323207
#> [14,] 4.560515 4.091983
#> [15,] 4.431760 4.424473
#> [16,] 4.835193 4.298734
#> ACCCACTGTACCTACA-500.2.2 ACCGTAACAACGATGG-500.2.2
#> [1,] 4.262943 4.289062
#> [2,] 4.012262 4.321289
#> [3,] 4.178474 4.450195
#> [4,] 4.831063 4.458008
#> [5,] 4.722071 4.384766
#> [6,] 4.243869 4.022461
#> [7,] 3.897820 4.101562
#> [8,] 4.814714 4.934570
#> [9,] 4.726158 4.792969
#> [10,] 4.370572 4.189453
#> [11,] 4.339237 4.016602
#> [12,] 4.059946 4.462891
#> [13,] 3.964578 4.359375
#> [14,] 4.509537 4.328125
#> [15,] 4.083106 4.378906
#> [16,] 4.604905 4.391602
#> ACCTTTAGTAGTACCT-500.2.2 ACGAGCCCACCTGGTG-500.2.2
#> [1,] 4.692073 4.355414
#> [2,] 4.185976 3.969427
#> [3,] 4.694106 4.668790
#> [4,] 4.183943 4.309554
#> [5,] 4.850610 4.639490
#> [6,] 4.585366 4.063694
#> [7,] 4.303862 4.286624
#> [8,] 5.359756 4.963057
#> [9,] 4.769309 4.612739
#> [10,] 4.223577 4.080255
#> [11,] 4.319106 4.062420
#> [12,] 4.712398 4.496815
#> [13,] 4.401423 4.350318
#> [14,] 4.197154 4.313376
#> [15,] 3.872967 4.319745
#> [16,] 4.191057 4.165605
#> ACGAGGAAGTGTGAAT-500.2.2 ACGATGTTCAAGAAGT-500.2.2
#> [1,] 4.675740 4.194614
#> [2,] 4.202367 4.292534
#> [3,] 4.512426 4.367197
#> [4,] 4.467456 4.589963
#> [5,] 4.157396 4.315789
#> [6,] 4.478107 4.020808
#> [7,] 4.364497 4.544676
#> [8,] 4.934911 4.849449
#> [9,] 4.614201 4.667075
#> [10,] 4.671006 4.356181
#> [11,] 4.203550 4.313341
#> [12,] 4.460355 4.358629
#> [13,] 4.429586 4.550796
#> [14,] 4.078107 4.596083
#> [15,] 3.871006 4.228886
#> [16,] 4.415385 4.330477
#> ACGCCGAAGGAATGGA-500.2.2 ACGGGCTTCTCGTATT-500.2.2
#> [1,] 4.350849 4.554980
#> [2,] 4.176233 4.526101
#> [3,] 4.599030 4.278786
#> [4,] 4.651576 4.491300
#> [5,] 4.380760 4.609034
#> [6,] 4.181083 4.741947
#> [7,] 4.136621 4.106257
#> [8,] 5.428456 4.850796
#> [9,] 4.947454 4.469826
#> [10,] 4.160873 4.365420
#> [11,] 4.536783 4.430581
#> [12,] 4.372676 4.443910
#> [13,] 3.962813 4.432803
#> [14,] 4.366209 4.366161
#> [15,] 4.567502 4.120326
#> [16,] 4.534357 4.178823
#> ACGTCAAAGCTAAGAT-500.2.2 ACTATCTAGAGCTGCA-500.2.2
#> [1,] 4.179104 4.683673
#> [2,] 4.214409 4.536107
#> [3,] 4.314294 4.252747
#> [4,] 3.932549 4.567504
#> [5,] 4.278416 4.563579
#> [6,] 4.175086 4.405808
#> [7,] 4.339265 4.248038
#> [8,] 4.632032 4.827316
#> [9,] 4.634328 4.319466
#> [10,] 4.238519 4.527473
#> [11,] 4.133180 4.485871
#> [12,] 4.355913 4.375981
#> [13,] 4.154994 4.517268
#> [14,] 4.466418 4.394819
#> [15,] 4.025545 4.178179
#> [16,] 4.326923 4.495290
#> ACTGAGTCAACTGCTA-500.2.2 ACTGAGTTCTGCCAGG-500.2.2
#> [1,] 4.191824 4.435195
#> [2,] 4.479036 3.933614
#> [3,] 4.541929 4.292940
#> [4,] 4.177149 4.177028
#> [5,] 4.898323 4.463646
#> [6,] 4.740042 4.758693
#> [7,] 4.360587 4.246575
#> [8,] 5.355346 4.747102
#> [9,] 4.596436 4.925184
#> [10,] 4.305031 4.347734
#> [11,] 4.799790 4.772392
#> [12,] 4.504193 4.459431
#> [13,] 4.436059 3.883035
#> [14,] 4.270440 4.774499
#> [15,] 4.292453 4.271865
#> [16,] 4.800839 4.462592
#> ACTGATGAGGGAACGG-500.2.2 ACTGATGTCGCATGGC-500.2.2
#> [1,] 4.028571 4.416361
#> [2,] 4.549107 4.629785
#> [3,] 4.735714 4.771893
#> [4,] 4.250000 4.587310
#> [5,] 4.993750 4.490299
#> [6,] 4.712500 3.865758
#> [7,] 4.141071 4.202412
#> [8,] 5.232143 4.662821
#> [9,] 4.402679 4.663346
#> [10,] 5.034821 4.476141
#> [11,] 4.922321 4.282643
#> [12,] 4.213393 4.340325
#> [13,] 4.416964 3.909806
#> [14,] 4.238393 4.381751
#> [15,] 4.158036 4.034609
#> [16,] 4.861607 4.271631
#> ACTTACTTCCTGTACC-500.2.2 ACTTGTTAGAAACGCC-500.2.2
#> [1,] 4.537709 4.250906
#> [2,] 4.942737 4.391304
#> [3,] 4.023743 4.431159
#> [4,] 4.213687 4.538949
#> [5,] 4.005587 4.419384
#> [6,] 4.230447 3.878623
#> [7,] 3.962291 4.137681
#> [8,] 4.477654 4.710145
#> [9,] 4.194134 5.060688
#> [10,] 4.506983 4.413949
#> [11,] 4.340782 4.327899
#> [12,] 4.750000 4.441123
#> [13,] 4.438547 4.090580
#> [14,] 4.349162 4.246377
#> [15,] 4.005587 4.440217
#> [16,] 4.198324 4.440217
#> ACTTGTTAGTACATGA-500.2.2 ACTTTCAAGCACAGGT-500.2.2
#> [1,] 4.592784 4.377069
#> [2,] 4.457474 3.881797
#> [3,] 4.340206 4.826241
#> [4,] 4.109536 4.247045
#> [5,] 4.533505 4.955083
#> [6,] 4.609536 5.059102
#> [7,] 4.122423 4.273050
#> [8,] 4.755155 4.956265
#> [9,] 4.511598 4.713948
#> [10,] 4.462629 4.074468
#> [11,] 4.586340 4.868794
#> [12,] 4.315722 4.411348
#> [13,] 4.458763 3.978723
#> [14,] 4.519330 4.667849
#> [15,] 4.033505 4.022459
#> [16,] 4.247423 4.722222
#> ACTTTCACATGTCGAT-500.2.2 ACTTTCAGTAAACACA-500.2.2
#> [1,] 4.465323 4.048649
#> [2,] 3.895968 3.960811
#> [3,] 4.408871 4.801351
#> [4,] 4.683871 3.908108
#> [5,] 4.387097 4.954054
#> [6,] 4.067742 5.343243
#> [7,] 4.451613 4.051351
#> [8,] 4.229032 4.656757
#> [9,] 4.657258 4.785135
#> [10,] 4.562903 4.404054
#> [11,] 4.562097 4.832432
#> [12,] 4.345968 4.760811
#> [13,] 4.341129 4.004054
#> [14,] 4.497581 5.201351
#> [15,] 4.290323 4.340541
#> [16,] 4.264516 4.906757
#> ACTTTCATCGGCATCG-500.2.2 AGAATAGCAGTCACTA-500.2.2
#> [1,] 4.2232 4.618198
#> [2,] 4.5336 4.240856
#> [3,] 4.5488 4.671722
#> [4,] 4.1776 4.597681
#> [5,] 4.9560 4.621766
#> [6,] 4.4736 4.218555
#> [7,] 4.2768 4.184657
#> [8,] 5.0136 4.810883
#> [9,] 4.3592 4.540589
#> [10,] 4.4400 4.558430
#> [11,] 4.7328 4.305085
#> [12,] 4.5304 4.542373
#> [13,] 4.4608 4.051740
#> [14,] 4.1600 4.199822
#> [15,] 4.2440 4.032114
#> [16,] 4.5328 4.268510
#> AGACGTTCAGGATTGG-500.2.2 AGACGTTTCACGCATA-500.2.2
#> [1,] 4.298490 4.599109
#> [2,] 4.032520 4.293987
#> [3,] 4.421603 4.595768
#> [4,] 4.405343 4.815145
#> [5,] 4.461092 4.446548
#> [6,] 4.098722 4.466592
#> [7,] 4.004646 4.276169
#> [8,] 4.703833 4.674833
#> [9,] 4.588850 4.262806
#> [10,] 4.096400 4.240535
#> [11,] 4.334495 4.430958
#> [12,] 4.348432 4.359688
#> [13,] 4.749129 4.457684
#> [14,] 3.926829 4.241648
#> [15,] 4.098722 4.551225
#> [16,] 4.960511 4.622494
#> AGAGCGAAGTCCTCCT-500.2.2 AGAGCTTAGCTACCGC-500.2.2
#> [1,] 4.658484 4.438561
#> [2,] 4.125632 4.251748
#> [3,] 4.371119 4.521479
#> [4,] 4.303971 4.524476
#> [5,] 4.865704 4.530470
#> [6,] 4.654152 4.163836
#> [7,] 4.261372 4.447552
#> [8,] 4.633213 4.749251
#> [9,] 4.761011 4.824176
#> [10,] 4.581227 4.226773
#> [11,] 4.616606 4.642358
#> [12,] 4.543682 4.435564
#> [13,] 4.282310 3.907093
#> [14,] 4.355235 4.113886
#> [15,] 4.294585 4.301698
#> [16,] 4.375451 4.154845
#> AGAGCTTCATCCGTGG-500.2.2 AGAGCTTGTGGACGAT-500.2.2
#> [1,] 4.319908 4.338296
#> [2,] 4.063291 4.304384
#> [3,] 4.225547 4.400331
#> [4,] 4.239356 4.148883
#> [5,] 4.398159 4.662531
#> [6,] 4.833142 4.369727
#> [7,] 4.211738 4.056245
#> [8,] 4.743383 5.119934
#> [9,] 4.377445 4.419355
#> [10,] 4.000000 4.708850
#> [11,] 4.147296 4.669975
#> [12,] 4.269275 4.386270
#> [13,] 4.327963 4.320926
#> [14,] 4.700806 4.134822
#> [15,] 4.254315 4.193548
#> [16,] 5.047181 4.363937
#> AGAGTGGCACATAACC-500.2.2 AGAGTGGCACGTTGGC-500.2.2
#> [1,] 4.238806 4.478760
#> [2,] 4.381954 4.438576
#> [3,] 4.356174 4.618829
#> [4,] 4.440299 4.252583
#> [5,] 4.720488 4.607348
#> [6,] 4.491859 4.355913
#> [7,] 4.194030 4.074627
#> [8,] 5.212347 4.505166
#> [9,] 4.619403 4.540758
#> [10,] 4.761194 4.096441
#> [11,] 4.496608 4.298507
#> [12,] 4.436228 4.448909
#> [13,] 4.285617 4.996556
#> [14,] 4.278833 4.321470
#> [15,] 4.265265 4.411022
#> [16,] 4.659430 4.336395
#> AGATCTGAGCTGAACG-500.2.2 AGCAGCCGTCCTCCAT-500.2.2
#> [1,] 4.308782 4.383981
#> [2,] 4.334278 4.184923
#> [3,] 4.571530 4.352179
#> [4,] 4.142351 4.563015
#> [5,] 4.451133 4.379270
#> [6,] 4.418555 4.552415
#> [7,] 4.134561 4.157833
#> [8,] 5.095609 4.897527
#> [9,] 4.593484 4.752650
#> [10,] 4.250000 4.135453
#> [11,] 4.289660 4.369847
#> [12,] 4.300992 4.290931
#> [13,] 4.158640 4.156655
#> [14,] 4.272663 4.706714
#> [15,] 4.181303 4.201413
#> [16,] 4.505666 4.538280
#> AGCCTAATCGTTTAGG-500.2.2 AGCGGTCTCTATGTGG-500.2.2
#> [1,] 4.627083 4.177288
#> [2,] 4.161458 4.381536
#> [3,] 4.671875 4.469771
#> [4,] 4.229167 4.464869
#> [5,] 4.597917 4.654412
#> [6,] 4.164583 4.222222
#> [7,] 3.884375 4.569444
#> [8,] 5.067708 4.660131
#> [9,] 4.408333 4.597222
#> [10,] 4.441667 4.396242
#> [11,] 4.127083 4.426471
#> [12,] 4.460417 4.402778
#> [13,] 4.695833 4.486111
#> [14,] 4.376042 4.409314
#> [15,] 4.088542 4.430556
#> [16,] 4.247917 4.591503
#> AGCGGTCTCTGGTATG-500.2.2 AGCTCCTCATTCCTCG-500.2.2
#> [1,] 4.391451 4.332461
#> [2,] 4.643420 4.322862
#> [3,] 4.469066 4.678883
#> [4,] 4.336333 4.218150
#> [5,] 4.352081 4.404887
#> [6,] 4.465692 4.605585
#> [7,] 4.032621 4.130890
#> [8,] 4.847019 4.956370
#> [9,] 4.278965 4.560209
#> [10,] 4.813273 4.298429
#> [11,] 4.635546 4.569808
#> [12,] 4.393701 4.512216
#> [13,] 4.303712 4.136126
#> [14,] 3.959505 4.390052
#> [15,] 3.822272 4.132635
#> [16,] 4.251969 4.621291
#> AGCTCCTTCCCTAATT-500.2.2 AGCTTGAAGCTAACTC-500.2.2
#> [1,] 4.491841 4.102925
#> [2,] 4.247669 4.681473
#> [3,] 4.565268 4.716143
#> [4,] 4.300699 4.862405
#> [5,] 4.532634 4.405200
#> [6,] 4.628788 4.355363
#> [7,] 4.071096 3.981582
#> [8,] 4.922494 4.795233
#> [9,] 4.705128 4.423619
#> [10,] 4.349650 4.432286
#> [11,] 4.585664 4.552546
#> [12,] 4.506993 4.366197
#> [13,] 4.096737 4.836403
#> [14,] 4.470862 4.095341
#> [15,] 4.327506 3.683640
#> [16,] 4.312937 4.507042
#> AGGCCACCACATTAGC-500.2.2 AGGCCGTGTCTCACCT-500.2.2
#> [1,] 4.143767 4.114504
#> [2,] 4.507734 4.076336
#> [3,] 4.431301 4.326972
#> [4,] 4.575978 4.933842
#> [5,] 4.189263 4.427481
#> [6,] 4.079163 4.304071
#> [7,] 4.049136 3.998728
#> [8,] 4.876251 4.917303
#> [9,] 5.090082 4.877863
#> [10,] 4.301183 4.516539
#> [11,] 4.255687 4.193384
#> [12,] 4.295723 4.568702
#> [13,] 4.035487 4.212468
#> [14,] 4.162875 4.424936
#> [15,] 4.365787 3.958015
#> [16,] 4.217470 4.291349
#> AGGGAGTAGTCAATAG-500.2.2 AGGGATGTCCCTTGCA-500.2.2
#> [1,] 4.622463 4.513550
#> [2,] 4.167794 4.391599
#> [3,] 4.380244 4.357724
#> [4,] 4.128552 4.401084
#> [5,] 4.323410 4.735772
#> [6,] 3.677943 4.524390
#> [7,] 3.817321 4.143631
#> [8,] 4.824087 5.060976
#> [9,] 4.453315 4.879404
#> [10,] 4.150203 4.279133
#> [11,] 4.037889 4.228997
#> [12,] 4.121786 4.597561
#> [13,] 4.527740 4.376694
#> [14,] 4.146143 4.604336
#> [15,] 3.968877 4.116531
#> [16,] 4.422192 4.277778
#> AGGTCATTCAAACGGG-500.2.2 AGGTCCGGTAAGGGAA-500.2.2
#> [1,] 4.500279 4.312303
#> [2,] 4.465103 4.305994
#> [3,] 4.270240 4.417455
#> [4,] 4.434953 4.542587
#> [5,] 4.527080 4.562566
#> [6,] 4.321608 4.243954
#> [7,] 4.315466 4.112513
#> [8,] 4.947515 4.932702
#> [9,] 4.618649 4.853838
#> [10,] 4.257956 4.534175
#> [11,] 4.331100 4.383807
#> [12,] 4.425461 4.596215
#> [13,] 4.262423 4.450053
#> [14,] 4.383585 4.668770
#> [15,] 4.150754 4.743428
#> [16,] 4.561139 4.414301
#> AGTAGTCTCTGGCGAC-500.2.2 AGTCTTTGTAAATACG-500.2.2
#> [1,] 4.462901 4.522843
#> [2,] 4.218162 4.377327
#> [3,] 4.728682 4.442470
#> [4,] 3.853821 4.254653
#> [5,] 4.469546 4.539763
#> [6,] 4.200443 4.300338
#> [7,] 3.899225 4.166667
#> [8,] 4.469546 4.774112
#> [9,] 4.460687 4.532149
#> [10,] 4.196013 4.336717
#> [11,] 4.272425 4.465313
#> [12,] 4.554817 4.324027
#> [13,] 4.165006 4.569374
#> [14,] 4.194906 4.451777
#> [15,] 4.504983 4.236041
#> [16,] 4.465116 4.467851
#> AGTGAGGAGAGGACGG-500.2.2 AGTGTCAAGGTGTTAA-500.2.2
#> [1,] 4.532625 4.487255
#> [2,] 4.371775 4.252941
#> [3,] 4.349772 4.548039
#> [4,] 4.225341 4.166667
#> [5,] 4.405159 4.686275
#> [6,] 4.536419 4.008824
#> [7,] 4.098634 4.222549
#> [8,] 4.905918 4.835294
#> [9,] 4.779970 4.796078
#> [10,] 4.312595 4.190196
#> [11,] 4.355083 4.223529
#> [12,] 4.634294 4.563725
#> [13,] 4.481791 4.479412
#> [14,] 4.391502 3.960784
#> [15,] 3.990895 3.784314
#> [16,] 4.572079 4.538235
#> ATAACGCGTAAGAGAG-500.2.2 ATCACGACAAGCTGGA-500.2.2
#> [1,] 4.667959 3.974558
#> [2,] 4.198966 4.266593
#> [3,] 4.494832 4.461283
#> [4,] 4.316537 4.418142
#> [5,] 4.441860 4.746681
#> [6,] 4.288114 4.361726
#> [7,] 4.178295 3.957965
#> [8,] 4.722222 4.648230
#> [9,] 5.156331 4.419248
#> [10,] 4.166667 4.820796
#> [11,] 4.350129 4.580752
#> [12,] 4.328165 4.506637
#> [13,] 4.264858 4.238938
#> [14,] 4.443152 4.282080
#> [15,] 4.071059 4.100664
#> [16,] 4.559432 4.349558
#> ATCCACCGTGTGCCTG-500.2.2 ATCCACCGTTAGATGA-500.2.2
#> [1,] 4.985946 4.397314
#> [2,] 5.632432 4.403633
#> [3,] 4.438919 4.543444
#> [4,] 3.854054 4.360979
#> [5,] 4.300541 4.360979
#> [6,] 5.002162 4.275671
#> [7,] 4.224865 4.168246
#> [8,] 4.768649 4.878357
#> [9,] 3.927568 4.798578
#> [10,] 4.158919 4.271722
#> [11,] 4.689730 4.375987
#> [12,] 5.254054 4.469194
#> [13,] 3.936216 3.992101
#> [14,] 4.087568 4.134281
#> [15,] 3.720000 4.300948
#> [16,] 3.913514 4.458136
#> ATCTACTTCGGCGCTA-500.2.2 ATCTGCCCACTGAAGG-500.2.2
#> [1,] 4.661937 4.928058
#> [2,] 4.434891 4.031655
#> [3,] 4.616027 4.801439
#> [4,] 4.363940 4.168345
#> [5,] 4.498331 4.349640
#> [6,] 4.504174 4.572662
#> [7,] 4.249583 4.123741
#> [8,] 4.883973 4.741007
#> [9,] 4.564274 4.497842
#> [10,] 4.362270 4.362590
#> [11,] 4.195326 4.316547
#> [12,] 4.479132 4.266187
#> [13,] 4.445743 4.530935
#> [14,] 4.391486 4.292086
#> [15,] 3.946578 4.230216
#> [16,] 4.227045 4.457554
#> ATCTGCCCATCACCCT-500.2.2 ATTACTCAGCTAGTGG-500.2.2
#> [1,] 4.654255 4.640335
#> [2,] 4.303191 5.053903
#> [3,] 4.402926 4.370818
#> [4,] 3.960106 4.122677
#> [5,] 4.164894 4.094796
#> [6,] 4.559840 4.915428
#> [7,] 4.196809 4.169145
#> [8,] 4.805851 4.561338
#> [9,] 4.812500 4.225836
#> [10,] 4.420213 4.565056
#> [11,] 4.394947 4.392193
#> [12,] 4.243351 4.741636
#> [13,] 4.518617 4.430297
#> [14,] 4.059840 4.360595
#> [15,] 3.909574 3.971190
#> [16,] 4.045213 4.026022
#> ATTGGACCATATGGTC-500.2.2 ATTGGTGGTCATACTG-500.2.2
#> [1,] 4.514975 4.381136
#> [2,] 4.455075 4.091434
#> [3,] 4.263727 4.337825
#> [4,] 4.394343 4.253128
#> [5,] 4.863561 4.248316
#> [6,] 4.465890 4.666025
#> [7,] 4.111481 3.934552
#> [8,] 4.824459 4.845043
#> [9,] 4.404326 4.346487
#> [10,] 4.847754 4.176131
#> [11,] 4.491681 4.204042
#> [12,] 4.217970 4.301251
#> [13,] 4.265391 4.346487
#> [14,] 4.390183 4.830606
#> [15,] 4.402662 4.082772
#> [16,] 4.592346 4.643888
#> ATTGGTGTCGTAGGAG-500.2.2 ATTGGTGTCTGCTTGC-500.2.2
#> [1,] 4.393711 4.206250
#> [2,] 4.206289 4.151042
#> [3,] 4.371069 4.316667
#> [4,] 4.342138 4.513542
#> [5,] 4.427673 4.460417
#> [6,] 4.358491 4.479167
#> [7,] 4.233962 4.194792
#> [8,] 4.852830 4.831250
#> [9,] 4.677987 4.770833
#> [10,] 4.115723 4.628125
#> [11,] 4.328302 4.707292
#> [12,] 4.488050 4.545833
#> [13,] 4.509434 4.278125
#> [14,] 4.588679 4.166667
#> [15,] 4.133333 4.479167
#> [16,] 4.129560 4.101042
#> ATTTCTGTCTGGGCCA-500.2.2 CAACCTCGTGGTTTCA-500.2.2
#> [1,] 4.580903 4.631908
#> [2,] 4.031044 4.194995
#> [3,] 4.101129 4.581856
#> [4,] 4.143462 4.226277
#> [5,] 4.679680 4.408759
#> [6,] 4.142992 4.398332
#> [7,] 4.358890 4.114703
#> [8,] 4.666510 4.807091
#> [9,] 4.638288 4.799791
#> [10,] 3.974130 4.295099
#> [11,] 4.077140 4.343066
#> [12,] 4.349483 4.570386
#> [13,] 4.696143 4.309698
#> [14,] 4.051740 4.530761
#> [15,] 4.024459 4.265902
#> [16,] 4.395579 4.380605
#> CAAGAAATCTGATTCT-500.2.2 CAAGTTGGTCCAGTTA-500.2.2
#> [1,] 4.674687 4.798918
#> [2,] 4.397498 4.229035
#> [3,] 4.509143 4.427412
#> [4,] 4.618864 4.272317
#> [5,] 4.681424 4.733093
#> [6,] 4.441771 4.024346
#> [7,] 4.369586 3.898106
#> [8,] 4.925890 5.092876
#> [9,] 4.472570 4.696123
#> [10,] 4.482194 4.113616
#> [11,] 4.312801 4.100992
#> [12,] 4.662175 4.469793
#> [13,] 4.058710 5.158702
#> [14,] 4.327238 4.488729
#> [15,] 4.264678 3.852119
#> [16,] 4.319538 4.605050
#> CACAGGCCAATCAGAA-500.2.2 CACAGTACAATCGGTT-500.2.2
#> [1,] 4.589226 4.662100
#> [2,] 4.349327 4.431507
#> [3,] 4.515993 4.347032
#> [4,] 4.082492 4.369863
#> [5,] 4.657407 4.455479
#> [6,] 4.414141 4.351598
#> [7,] 4.213805 4.200913
#> [8,] 4.850168 4.779680
#> [9,] 5.019360 4.914384
#> [10,] 4.250000 4.474886
#> [11,] 4.270202 4.214612
#> [12,] 4.510101 4.311644
#> [13,] 4.450337 4.552511
#> [14,] 4.421717 4.469178
#> [15,] 3.962121 4.350457
#> [16,] 4.497475 4.337900
#> CACAGTATCGCAAGCC-500.2.2 CACATAGCAGTAGAGC-500.2.2
#> [1,] 4.267349 4.397835
#> [2,] 4.686007 4.300666
#> [3,] 4.412969 4.633537
#> [4,] 4.410694 4.160189
#> [5,] 4.393629 4.467240
#> [6,] 4.356086 4.411438
#> [7,] 4.162685 4.198223
#> [8,] 4.687144 4.646863
#> [9,] 4.858931 4.715991
#> [10,] 4.839590 4.121321
#> [11,] 4.470990 4.410605
#> [12,] 4.251422 4.414770
#> [13,] 4.168373 4.358412
#> [14,] 4.548350 4.328151
#> [15,] 4.683732 4.285397
#> [16,] 4.340159 4.581621
#> CACATAGTCTGTACGA-500.2.2 CACATAGTCTTTAGTC-500.2.2
#> [1,] 4.201422 4.381625
#> [2,] 4.169431 3.946996
#> [3,] 4.395735 4.921084
#> [4,] 4.766588 4.380448
#> [5,] 4.620853 4.359246
#> [6,] 4.296209 4.485277
#> [7,] 4.144550 4.076561
#> [8,] 4.919431 5.303887
#> [9,] 5.175355 4.292108
#> [10,] 4.267773 4.194346
#> [11,] 4.264218 4.670200
#> [12,] 3.880332 4.504122
#> [13,] 4.081754 3.977621
#> [14,] 4.095972 4.018846
#> [15,] 4.261848 4.290931
#> [16,] 4.611374 4.170789
#> CACATTTGTTAGTGGG-500.2.2 CACCACTCATCAGTCA-500.2.2
#> [1,] 4.298435 4.422925
#> [2,] 4.137075 4.140975
#> [3,] 4.701565 4.333333
#> [4,] 4.074474 4.393939
#> [5,] 4.497572 4.467721
#> [6,] 4.642742 4.322793
#> [7,] 4.461414 3.919631
#> [8,] 5.184026 4.581028
#> [9,] 4.596870 4.674572
#> [10,] 4.342688 4.208169
#> [11,] 4.756071 4.150198
#> [12,] 4.676201 4.139657
#> [13,] 4.185105 4.544137
#> [14,] 4.320022 4.566535
#> [15,] 4.428494 4.214756
#> [16,] 4.793308 4.391304
#> CACCAGGCATAGAAAC-500.2.2 CACCAGGGTGAGGCTA-500.2.2
#> [1,] 4.633776 4.458832
#> [2,] 4.147059 4.021816
#> [3,] 4.399431 4.508797
#> [4,] 4.268501 4.163969
#> [5,] 4.522770 4.578466
#> [6,] 4.633776 4.786770
#> [7,] 3.976281 4.287122
#> [8,] 4.774194 4.928923
#> [9,] 4.623340 4.951443
#> [10,] 4.160342 4.515834
#> [11,] 4.267552 4.837438
#> [12,] 4.468691 4.358198
#> [13,] 4.867173 4.078114
#> [14,] 4.239089 4.515834
#> [15,] 4.161290 4.065447
#> [16,] 4.541746 4.446868
#> CACTCCAAGATGTAAC-500.2.2 CACTCCAAGCCAGTAG-500.2.2
#> [1,] 4.362319 4.557522
#> [2,] 4.313665 4.164349
#> [3,] 4.524845 4.405815
#> [4,] 4.319876 4.201011
#> [5,] 4.348861 4.470291
#> [6,] 4.866460 4.556258
#> [7,] 4.093168 4.107459
#> [8,] 4.553830 4.647282
#> [9,] 4.572464 4.973451
#> [10,] 4.246377 4.474083
#> [11,] 4.513458 4.307206
#> [12,] 4.602484 4.223767
#> [13,] 3.786749 4.359039
#> [14,] 4.511387 4.984829
#> [15,] 4.379917 4.620733
#> [16,] 4.646998 4.463970
#> CACTCCACACACCGCA-500.2.2 CAGAGAGTCTTGTTTG-500.2.2
#> [1,] 4.341560 4.259978
#> [2,] 4.268509 4.117584
#> [3,] 4.854886 3.963323
#> [4,] 4.578480 3.903991
#> [5,] 4.744324 3.841424
#> [6,] 3.973346 4.664509
#> [7,] 3.894373 4.056095
#> [8,] 4.812438 4.490831
#> [9,] 4.449161 4.775620
#> [10,] 4.300099 4.096009
#> [11,] 4.547878 3.990291
#> [12,] 4.546890 4.578209
#> [13,] 4.728529 4.174757
#> [14,] 4.018756 5.042071
#> [15,] 4.312932 4.072276
#> [16,] 4.349457 4.719525
#> CAGCAGCAGTGATCGG-500.2.2 CAGCAGCCACGCTTTC-500.2.2
#> [1,] 4.596567 4.266760
#> [2,] 4.327611 4.349860
#> [3,] 4.244635 4.476955
#> [4,] 4.339056 4.354749
#> [5,] 4.583691 4.240922
#> [6,] 4.376252 4.390363
#> [7,] 4.208870 4.259078
#> [8,] 4.957082 4.663408
#> [9,] 4.825465 4.937849
#> [10,] 4.489270 4.415503
#> [11,] 4.281831 4.387570
#> [12,] 4.336195 4.277235
#> [13,] 4.693848 4.263966
#> [14,] 4.210300 4.480447
#> [15,] 4.015737 4.465084
#> [16,] 4.659514 4.327514
#> CAGCAGCCATGGGACA-500.2.2 CAGCGACGTCTAGTGT-500.2.2
#> [1,] 4.688973 3.998594
#> [2,] 4.341188 4.167370
#> [3,] 4.535344 4.535865
#> [4,] 4.361923 4.225035
#> [5,] 4.445806 4.479606
#> [6,] 4.350613 4.233474
#> [7,] 3.988690 4.289733
#> [8,] 4.821866 4.784810
#> [9,] 4.557964 4.521800
#> [10,] 4.653157 4.371308
#> [11,] 4.135721 4.268636
#> [12,] 4.645617 4.555556
#> [13,] 4.329877 4.586498
#> [14,] 4.385485 4.251758
#> [15,] 4.223374 3.794655
#> [16,] 4.285580 4.406470
#> CAGCTGGAGTCCAGGA-500.2.2 CAGCTGGGTACAGTGG-500.2.2
#> [1,] 4.739290 4.483254
#> [2,] 4.695226 4.281100
#> [3,] 4.107711 4.589713
#> [4,] 4.137087 4.343301
#> [5,] 4.053856 4.065789
#> [6,] 4.603427 4.340909
#> [7,] 3.905753 4.232057
#> [8,] 5.050184 4.857656
#> [9,] 4.627907 4.582536
#> [10,] 4.607099 4.272727
#> [11,] 4.392901 4.417464
#> [12,] 4.428397 4.474880
#> [13,] 4.392901 4.382775
#> [14,] 4.152999 4.263158
#> [15,] 3.953488 4.139952
#> [16,] 4.286414 4.325359
#> CAGCTGGTCACTGGGC-500.2.2 CAGCTGGTCGCATGGC-500.2.2
#> [1,] 4.581709 3.761877
#> [2,] 4.178411 4.075660
#> [3,] 4.660420 4.656305
#> [4,] 4.251124 3.922581
#> [5,] 4.721889 4.007625
#> [6,] 4.325337 3.620528
#> [7,] 4.125187 5.235777
#> [8,] 4.695652 4.730792
#> [9,] 4.433283 4.391202
#> [10,] 4.445277 4.224047
#> [11,] 4.570465 3.702639
#> [12,] 4.424288 4.217009
#> [13,] 4.228636 3.488563
#> [14,] 4.578711 3.751906
#> [15,] 4.344828 3.494428
#> [16,] 4.490255 5.390616
#> CAGGTGCCAAGTACCT-500.2.2 CAGTCCTCAGCTCCGA-500.2.2
#> [1,] 4.530108 4.551941
#> [2,] 5.030108 4.622246
#> [3,] 4.884946 4.593914
#> [4,] 4.192473 4.337880
#> [5,] 4.206452 4.323190
#> [6,] 4.446237 4.038825
#> [7,] 4.005376 4.175236
#> [8,] 4.615054 4.695698
#> [9,] 4.063441 4.870934
#> [10,] 4.234409 4.864638
#> [11,] 4.901075 4.385100
#> [12,] 4.882796 4.449108
#> [13,] 4.134409 4.330535
#> [14,] 4.031183 4.337880
#> [15,] 4.004301 4.855194
#> [16,] 4.061290 4.284365
#> CATATGGTCCGTTGCT-500.2.2 CATCAAGCACATTTCT-500.2.2
#> [1,] 4.830321 4.354659
#> [2,] 4.815261 4.337969
#> [3,] 4.221888 4.694019
#> [4,] 4.430723 4.095967
#> [5,] 4.168675 4.902643
#> [6,] 4.374498 4.709318
#> [7,] 4.140562 4.242003
#> [8,] 4.676707 5.300417
#> [9,] 4.212851 4.191933
#> [10,] 4.519076 4.102921
#> [11,] 4.619478 4.959666
#> [12,] 4.821285 4.388039
#> [13,] 4.832329 4.368567
#> [14,] 4.231928 4.278164
#> [15,] 3.928715 4.265647
#> [16,] 4.159639 4.709318
#> CATCCACTCGTCACGG-500.2.2 CATCGAACAAGACACG-500.2.2
#> [1,] 4.671385 4.385120
#> [2,] 4.452983 4.351568
#> [3,] 4.339737 4.356674
#> [4,] 4.552073 4.557257
#> [5,] 4.281092 4.396061
#> [6,] 4.124368 3.964989
#> [7,] 4.270981 4.568198
#> [8,] 4.528817 4.718454
#> [9,] 4.728008 5.034282
#> [10,] 4.858443 4.237053
#> [11,] 4.844287 4.465354
#> [12,] 4.131446 4.455142
#> [13,] 4.219414 4.529540
#> [14,] 4.325581 4.357403
#> [15,] 4.714863 4.331145
#> [16,] 3.866532 4.224654
#> CATCGGGTCAGCCTAA-500.2.2 CATGCCTAGAATAGGG-500.2.2
#> [1,] 4.716083 4.509606
#> [2,] 4.639712 4.399393
#> [3,] 4.308176 4.368049
#> [4,] 4.417790 4.655207
#> [5,] 4.567835 4.309403
#> [6,] 4.233603 4.304348
#> [7,] 4.083558 3.950455
#> [8,] 4.602875 4.959555
#> [9,] 4.515723 4.645096
#> [10,] 4.233603 4.230536
#> [11,] 4.436658 4.361982
#> [12,] 4.486972 4.483316
#> [13,] 4.741240 4.378160
#> [14,] 4.310872 4.553084
#> [15,] 4.099730 4.131446
#> [16,] 4.099730 4.348837
#> CATTATCAGCCACGTC-500.2.2 CATTATCCACACGCTG-500.2.2
#> [1,] 5.049954 4.032421
#> [2,] 4.552266 4.359676
#> [3,] 4.526364 4.350557
#> [4,] 4.315449 4.492401
#> [5,] 4.832562 5.326241
#> [6,] 4.226642 4.963526
#> [7,] 4.098982 4.349544
#> [8,] 4.840888 5.045593
#> [9,] 5.091582 4.090172
#> [10,] 4.146161 4.291793
#> [11,] 4.298797 4.537994
#> [12,] 4.506938 4.673759
#> [13,] 4.854764 4.463019
#> [14,] 4.482886 4.443769
#> [15,] 4.111008 4.449848
#> [16,] 4.486586 4.618034
#> CATTATCGTTCGTGAT-500.2.2 CCAGCGAGTCAGATAA-500.2.2
#> [1,] 4.648910 4.260916
#> [2,] 4.232446 4.129925
#> [3,] 4.453995 4.366347
#> [4,] 4.688862 4.241747
#> [5,] 4.188862 4.354633
#> [6,] 4.221550 4.446219
#> [7,] 4.242131 4.280085
#> [8,] 4.772397 4.961661
#> [9,] 5.175545 5.082002
#> [10,] 4.162228 4.283280
#> [11,] 4.480630 4.214058
#> [12,] 4.381356 4.266241
#> [13,] 4.263923 4.227902
#> [14,] 4.117433 4.274760
#> [15,] 4.018160 4.507987
#> [16,] 4.359564 4.458999
#> CCATGTCCAAGCGTAG-500.2.2 CCATGTCGTCATCCCT-500.2.2
#> [1,] 4.557430 4.370208
#> [2,] 4.477108 4.595838
#> [3,] 4.751004 4.575027
#> [4,] 4.492369 4.381161
#> [5,] 4.560643 4.175246
#> [6,] 4.421687 4.330778
#> [7,] 4.297189 4.125958
#> [8,] 4.741365 5.076670
#> [9,] 4.602410 4.698795
#> [10,] 4.248996 4.401972
#> [11,] 4.364659 4.336254
#> [12,] 4.576707 4.248631
#> [13,] 4.439357 4.534502
#> [14,] 4.327711 4.429354
#> [15,] 4.382329 4.622125
#> [16,] 4.157430 4.401972
#> CCCAATCGTCTAGGTT-500.2.2 CCCAATCTCGATCCCT-500.2.2
#> [1,] 4.168441 4.245655
#> [2,] 4.519845 4.095017
#> [3,] 4.414327 4.544612
#> [4,] 4.193611 4.461182
#> [5,] 4.287512 4.324450
#> [6,] 4.152953 4.527231
#> [7,] 4.246854 3.951333
#> [8,] 5.175218 4.831981
#> [9,] 4.828654 4.940904
#> [10,] 4.261375 4.768250
#> [11,] 4.606970 4.504056
#> [12,] 4.492740 4.304751
#> [13,] 4.332043 4.333720
#> [14,] 4.179090 4.640788
#> [15,] 4.388190 4.221321
#> [16,] 4.259439 4.194670
#> CCCATACAGAATTCCC-500.2.2 CCCTCCTGTGAGCGAT-500.2.2
#> [1,] 4.315730 4.368700
#> [2,] 4.231461 4.461538
#> [3,] 4.285393 4.494695
#> [4,] 4.342697 4.830239
#> [5,] 4.678652 4.558355
#> [6,] 4.496629 3.966844
#> [7,] 4.332584 4.236074
#> [8,] 4.756180 4.631300
#> [9,] 4.549438 5.023873
#> [10,] 4.110112 5.118037
#> [11,] 3.929213 4.187003
#> [12,] 4.379775 4.671088
#> [13,] 4.539326 4.364721
#> [14,] 4.622472 4.352785
#> [15,] 4.033708 4.594164
#> [16,] 4.480899 4.358090
#> CCGGTAGAGCGGATCA-500.2.2 CCGTACTCACAGGTTT-500.2.2
#> [1,] 4.267116 4.174713
#> [2,] 4.409652 4.022989
#> [3,] 4.462402 4.164368
#> [4,] 3.995511 3.947126
#> [5,] 4.454545 3.960920
#> [6,] 4.518519 5.129885
#> [7,] 4.123457 3.947126
#> [8,] 5.039282 4.858621
#> [9,] 4.689113 4.585057
#> [10,] 4.297419 4.143678
#> [11,] 4.257015 3.849425
#> [12,] 4.262626 4.477011
#> [13,] 4.442200 4.271264
#> [14,] 4.443322 4.872414
#> [15,] 4.135802 4.143678
#> [16,] 4.442200 4.849425
#> CCGTACTGTCTAGCGC-500.2.2 CCGTACTTCACGCATA-500.2.2
#> [1,] 4.677392 4.260292
#> [2,] 4.757832 4.261620
#> [3,] 4.668078 4.545817
#> [4,] 4.487722 4.322709
#> [5,] 4.713802 4.490040
#> [6,] 4.344623 4.197875
#> [7,] 4.027942 3.879150
#> [8,] 5.288738 4.686587
#> [9,] 4.637595 5.037185
#> [10,] 4.232007 4.308101
#> [11,] 4.328535 4.261620
#> [12,] 4.480948 4.074369
#> [13,] 4.292972 4.232404
#> [14,] 4.273497 4.288181
#> [15,] 4.012701 4.277556
#> [16,] 4.298899 4.470120
#> CCGTACTTCAGGCGAA-500.2.2 CCGTGGAAGCGGATCA-500.2.2
#> [1,] 4.298548 4.426244
#> [2,] 4.117967 4.135747
#> [3,] 4.370236 4.545701
#> [4,] 4.691470 4.674208
#> [5,] 4.404719 4.266968
#> [6,] 4.620690 4.038914
#> [7,] 3.914701 4.434389
#> [8,] 5.000000 4.452489
#> [9,] 5.097096 4.556561
#> [10,] 4.693285 4.330317
#> [11,] 4.549002 4.600000
#> [12,] 4.434664 4.315837
#> [13,] 3.980944 4.650679
#> [14,] 3.941924 4.274208
#> [15,] 4.355717 4.718552
#> [16,] 4.289474 4.203620
#> CCGTGGAGTCAGAGGT-500.2.2 CCGTGGATCCTCCTAG-500.2.2
#> [1,] 4.570601 4.198857
#> [2,] 4.078928 4.542857
#> [3,] 4.661839 4.465143
#> [4,] 4.044171 4.245714
#> [5,] 4.513396 4.203429
#> [6,] 4.836350 4.476571
#> [7,] 3.918175 3.964571
#> [8,] 4.818972 4.829714
#> [9,] 4.596669 4.604571
#> [10,] 4.509051 4.152000
#> [11,] 4.582911 4.389714
#> [12,] 4.354091 4.330286
#> [13,] 4.207096 4.315429
#> [14,] 4.674873 4.451429
#> [15,] 4.315713 4.445714
#> [16,] 4.241130 4.392000
#> CCTAAAGTCTAACTGG-500.2.2 CCTAGCTGTGCACGAA-500.2.2
#> [1,] 4.547696 4.579652
#> [2,] 4.246593 3.967871
#> [3,] 4.472421 4.358768
#> [4,] 4.637249 3.919679
#> [5,] 4.452304 4.508701
#> [6,] 4.269955 4.732262
#> [7,] 4.432187 4.236948
#> [8,] 4.855938 5.030790
#> [9,] 4.541856 4.720214
#> [10,] 4.527579 3.946452
#> [11,] 4.437378 4.111111
#> [12,] 4.472421 4.057564
#> [13,] 4.732641 4.273092
#> [14,] 4.190785 4.546185
#> [15,] 4.776119 4.314592
#> [16,] 4.173913 4.730924
#> CCTATTACACAGTCGC-500.2.2 CCTATTACACTGAAGG-500.2.2
#> [1,] 4.592313 4.197722
#> [2,] 4.026081 3.960130
#> [3,] 4.515443 4.432059
#> [4,] 4.269046 4.388120
#> [5,] 4.906658 4.825875
#> [6,] 4.638984 4.628967
#> [7,] 4.304736 4.162734
#> [8,] 4.765957 4.901546
#> [9,] 4.700755 4.545159
#> [10,] 4.308167 4.845403
#> [11,] 4.582018 4.670464
#> [12,] 4.386410 4.300244
#> [13,] 4.065202 4.350692
#> [14,] 4.662320 4.304312
#> [15,] 4.414550 4.222132
#> [16,] 4.391215 4.467046
#> CCTCAGTTCGCCTGTT-500.2.2 CCTTCCCGTGTGGTTT-500.2.2
#> [1,] 4.571141 4.459054
#> [2,] 4.468456 4.392157
#> [3,] 4.520134 4.605536
#> [4,] 4.044966 4.474048
#> [5,] 4.504698 4.561707
#> [6,] 4.489933 4.277970
#> [7,] 4.040940 4.249135
#> [8,] 4.953020 4.486736
#> [9,] 4.841611 4.821223
#> [10,] 4.124161 4.378316
#> [11,] 4.365772 4.212226
#> [12,] 4.397987 4.771626
#> [13,] 4.369128 4.389850
#> [14,] 4.480537 4.167243
#> [15,] 4.237584 4.346021
#> [16,] 4.470470 4.423299
#> CGAACATAGATATACG-500.2.2 CGAACATGTGTGGTTT-500.2.2
#> [1,] 4.559710 4.311252
#> [2,] 4.688782 4.313975
#> [3,] 4.611580 4.838475
#> [4,] 4.361882 4.468240
#> [5,] 4.522316 4.232305
#> [6,] 4.358263 4.266788
#> [7,] 4.158022 4.051724
#> [8,] 4.942099 5.130672
#> [9,] 4.677925 4.774955
#> [10,] 4.433052 4.228675
#> [11,] 4.772014 4.443739
#> [12,] 4.600724 4.558984
#> [13,] 4.586248 4.132486
#> [14,] 4.255730 4.382940
#> [15,] 4.250905 4.332123
#> [16,] 4.388420 4.230490
#> CGAATGTCAGACAGGT-500.2.2 CGAATGTTCATGTGGT-500.2.2
#> [1,] 4.190217 4.438226
#> [2,] 3.929348 4.223865
#> [3,] 4.119565 4.650475
#> [4,] 4.216033 4.532207
#> [5,] 4.644022 4.567054
#> [6,] 3.972826 4.186906
#> [7,] 4.088315 4.453010
#> [8,] 4.822011 4.971489
#> [9,] 4.673913 4.620908
#> [10,] 3.975543 4.381204
#> [11,] 3.824728 4.446674
#> [12,] 4.233696 4.374868
#> [13,] 4.601902 4.294615
#> [14,] 4.657609 4.369588
#> [15,] 4.248641 4.186906
#> [16,] 4.421196 4.047518
#> CGACCTTTCGGAATCT-500.2.2 CGACTTCAGAAGAAGC-500.2.2
#> [1,] 4.520366 4.442455
#> [2,] 4.052369 4.363171
#> [3,] 4.673317 4.624041
#> [4,] 4.411471 4.484228
#> [5,] 4.641729 4.496164
#> [6,] 4.599335 4.146633
#> [7,] 3.768911 4.245524
#> [8,] 5.198670 5.135550
#> [9,] 4.474647 4.768968
#> [10,] 4.245220 4.560955
#> [11,] 4.299252 4.383632
#> [12,] 4.560266 4.311168
#> [13,] 4.603491 4.417732
#> [14,] 4.091438 4.314578
#> [15,] 4.142976 4.196078
#> [16,] 4.439734 4.295823
#> CGACTTCAGCGTGAGT-500.2.2 CGACTTCAGTGACATA-500.2.2
#> [1,] 4.540473 4.677461
#> [2,] 4.255293 4.142487
#> [3,] 4.591532 4.624352
#> [4,] 4.529265 4.357513
#> [5,] 4.087173 4.436528
#> [6,] 4.058531 4.338083
#> [7,] 4.217933 4.477979
#> [8,] 4.814446 5.037565
#> [9,] 4.901619 4.509067
#> [10,] 4.331258 4.490933
#> [11,] 4.165629 4.220207
#> [12,] 4.320050 4.362694
#> [13,] 4.361146 4.332902
#> [14,] 4.430884 4.427461
#> [15,] 4.265255 4.119171
#> [16,] 4.097136 4.415803
#> CGAGCACGTAGGGTAC-500.2.2 CGATGGCGTTGGTGGA-500.2.2
#> [1,] 4.430416 4.471264
#> [2,] 4.229555 4.377542
#> [3,] 4.668580 4.283820
#> [4,] 4.018651 4.780725
#> [5,] 4.757532 4.567639
#> [6,] 4.275466 4.000000
#> [7,] 4.276901 4.057471
#> [8,] 4.826399 4.793988
#> [9,] 4.391679 4.641910
#> [10,] 4.393113 4.354553
#> [11,] 3.946915 4.167109
#> [12,] 4.538020 4.138815
#> [13,] 4.526542 4.524315
#> [14,] 4.302726 4.452697
#> [15,] 4.035868 4.332449
#> [16,] 4.497848 4.259947
#> CGCGGTAAGTACGCGA-500.2.2 CGCTATCGTAGGAGTC-500.2.2
#> [1,] 4.436600 4.397929
#> [2,] 4.258396 4.353597
#> [3,] 4.472241 4.382798
#> [4,] 4.252913 4.376692
#> [5,] 4.627827 4.327316
#> [6,] 4.114462 4.392620
#> [7,] 4.488691 4.149721
#> [8,] 4.808088 4.787629
#> [9,] 4.758739 4.740908
#> [10,] 4.128170 4.266791
#> [11,] 4.152159 4.526148
#> [12,] 4.793009 4.496416
#> [13,] 4.651816 4.259889
#> [14,] 4.220014 4.482347
#> [15,] 4.281014 4.344837
#> [16,] 4.185744 4.511017
#> CGCTGGAAGAACTGTA-500.2.2 CGCTGGACAGATCGGA-500.2.2
#> [1,] 4.237094 4.319630
#> [2,] 4.621415 4.127441
#> [3,] 4.648184 4.337102
#> [4,] 4.337476 3.918808
#> [5,] 4.333652 4.200411
#> [6,] 3.993308 4.664954
#> [7,] 4.265774 4.201439
#> [8,] 5.000000 4.701953
#> [9,] 4.727533 4.787256
#> [10,] 4.749522 4.228160
#> [11,] 4.252390 4.159301
#> [12,] 4.126195 4.113052
#> [13,] 4.601338 4.499486
#> [14,] 4.413958 4.342240
#> [15,] 4.600382 3.980473
#> [16,] 4.155832 4.558068
#> CGCTTCACAACTGCTA-500.2.2 CGGACACAGCCTCGTG-500.2.2
#> [1,] 4.342735 4.420091
#> [2,] 4.338462 4.212329
#> [3,] 4.600855 4.477930
#> [4,] 4.331624 4.329528
#> [5,] 4.280342 4.805175
#> [6,] 4.223932 4.694825
#> [7,] 4.478632 4.305175
#> [8,] 5.001709 4.622527
#> [9,] 4.394017 4.431507
#> [10,] 4.418803 4.359209
#> [11,] 4.335897 4.845510
#> [12,] 4.518803 4.324962
#> [13,] 4.511966 4.094368
#> [14,] 4.468376 4.372146
#> [15,] 4.404274 4.152207
#> [16,] 4.103419 4.418569
#> CGGACACAGTGATCGG-500.2.2 CGGACGTGTCAATACC-500.2.2
#> [1,] 4.401451 4.318745
#> [2,] 4.141475 4.293146
#> [3,] 4.721886 4.573906
#> [4,] 4.573156 4.230388
#> [5,] 4.507860 4.478943
#> [6,] 4.324063 4.667217
#> [7,] 4.016929 4.289017
#> [8,] 4.646917 4.663914
#> [9,] 5.315599 4.935590
#> [10,] 4.365175 4.308836
#> [11,] 4.114873 4.710983
#> [12,] 4.379686 4.279108
#> [13,] 4.717050 4.049546
#> [14,] 4.169287 4.420314
#> [15,] 4.105200 4.256813
#> [16,] 4.581620 4.662263
#> CGGACGTTCTTTACAC-500.2.2 CGGACTGAGGTTCCTA-500.2.2
#> [1,] 4.233809 4.768863
#> [2,] 4.046103 4.376313
#> [3,] 4.724479 4.323782
#> [4,] 4.569704 4.424069
#> [5,] 4.384193 4.626552
#> [6,] 4.003293 4.312321
#> [7,] 4.087816 3.931232
#> [8,] 5.166850 4.867240
#> [9,] 4.710209 4.808978
#> [10,] 4.075741 4.225406
#> [11,] 4.700329 4.506208
#> [12,] 4.318332 4.518625
#> [13,] 3.982437 4.897803
#> [14,] 4.386389 4.248329
#> [15,] 4.830955 4.250239
#> [16,] 4.340285 4.223496
#> CGGACTGCATGCTGGC-500.2.2 CGGAGCTCAAGACGTG-500.2.2
#> [1,] 4.455939 4.727273
#> [2,] 4.715517 4.304075
#> [3,] 4.393678 4.530825
#> [4,] 4.612069 4.611285
#> [5,] 3.991379 4.526646
#> [6,] 3.964559 4.289446
#> [7,] 3.937739 4.317659
#> [8,] 4.899425 4.569488
#> [9,] 4.580460 4.455590
#> [10,] 4.635057 4.121212
#> [11,] 4.454023 4.285266
#> [12,] 4.228927 4.657262
#> [13,] 4.486590 4.855799
#> [14,] 4.236590 4.384535
#> [15,] 4.511494 4.239289
#> [16,] 4.268199 4.254963
#> CGGAGTCTCCAACCAA-500.2.2 CGGCTAGAGTCCTCCT-500.2.2
#> [1,] 4.130163 4.506931
#> [2,] 4.663329 5.097030
#> [3,] 4.653317 4.532673
#> [4,] 4.354193 4.564356
#> [5,] 4.536921 4.144554
#> [6,] 4.217772 4.395050
#> [7,] 3.986233 4.237624
#> [8,] 4.962453 4.770297
#> [9,] 4.843554 4.128713
#> [10,] 4.331665 4.341584
#> [11,] 4.224030 4.655446
#> [12,] 4.911139 4.657426
#> [13,] 4.350438 4.135644
#> [14,] 4.210263 4.232673
#> [15,] 3.882353 3.709901
#> [16,] 4.720901 4.382178
#> CGGGTCATCTCTTGAT-500.2.2 CGTCAGGGTAAACCTC-500.2.2
#> [1,] 4.336124 4.349835
#> [2,] 3.892344 4.611661
#> [3,] 4.489234 4.595160
#> [4,] 4.141148 4.754675
#> [5,] 4.726077 4.415842
#> [6,] 4.733254 4.075908
#> [7,] 4.160287 4.254125
#> [8,] 4.771531 4.684268
#> [9,] 5.031100 5.205721
#> [10,] 4.665072 4.983498
#> [11,] 4.660287 4.372937
#> [12,] 4.387560 4.316832
#> [13,] 4.084928 4.275028
#> [14,] 4.551435 4.539054
#> [15,] 4.186603 5.001100
#> [16,] 4.545455 3.770077
#> CGTTAGAAGCAGCCTC-500.2.2 CGTTCTGGTATGCTTG-500.2.2
#> [1,] 4.238220 4.411980
#> [2,] 4.691099 4.127139
#> [3,] 4.544503 4.555012
#> [4,] 4.359948 4.528117
#> [5,] 4.638743 4.053790
#> [6,] 4.178010 4.345966
#> [7,] 4.472513 4.013447
#> [8,] 4.730366 4.581907
#> [9,] 4.671466 5.045232
#> [10,] 4.446335 4.597800
#> [11,] 4.304974 4.243276
#> [12,] 4.599476 4.525672
#> [13,] 4.386126 4.305623
#> [14,] 4.345550 4.266504
#> [15,] 3.786649 4.075795
#> [16,] 4.146597 4.431540
#> CTAATGGTCATTCACT-500.2.2 CTACATTGTCATACTG-500.2.2
#> [1,] 4.340955 4.253628
#> [2,] 4.543376 4.253628
#> [3,] 4.581036 4.642902
#> [4,] 4.474109 4.262461
#> [5,] 4.398117 4.774132
#> [6,] 4.100202 4.618927
#> [7,] 4.131137 4.258675
#> [8,] 4.613315 4.945110
#> [9,] 5.013450 4.470662
#> [10,] 5.090114 4.244164
#> [11,] 4.537323 4.801893
#> [12,] 4.429724 4.164669
#> [13,] 4.216543 4.197476
#> [14,] 4.521856 4.798107
#> [15,] 4.701412 4.235331
#> [16,] 4.171486 4.464984
#> CTCACACAGTGGTCCC-500.2.2 CTCAGAATCTTAACCT-500.2.2
#> [1,] 4.417558 5.052948
#> [2,] 4.624292 5.843562
#> [3,] 4.476715 4.709988
#> [4,] 4.240717 3.909747
#> [5,] 4.556954 4.031288
#> [6,] 4.345500 5.087846
#> [7,] 4.254877 4.182912
#> [8,] 4.694462 4.219013
#> [9,] 4.624607 3.844765
#> [10,] 4.309629 4.268351
#> [11,] 4.264947 4.862816
#> [12,] 4.508496 5.432010
#> [13,] 4.428257 4.388688
#> [14,] 4.181875 4.099880
#> [15,] 4.370359 3.762936
#> [16,] 4.504091 4.069795
#> CTCCTAGTCCTGTAGA-500.2.2 CTCGGAGGTGAGGGTT-500.2.2
#> [1,] 4.494927 4.455925
#> [2,] 4.631342 4.233382
#> [3,] 4.545660 4.415462
#> [4,] 4.210823 4.445809
#> [5,] 4.455468 4.484104
#> [6,] 4.068771 4.439306
#> [7,] 4.182638 4.289017
#> [8,] 4.794814 5.006503
#> [9,] 4.714769 4.606214
#> [10,] 4.328072 4.459538
#> [11,] 4.545660 4.395231
#> [12,] 4.571590 4.478324
#> [13,] 4.383315 4.549855
#> [14,] 4.279594 4.299133
#> [15,] 4.489290 3.970376
#> [16,] 4.475761 4.377168
#> CTCGGGACAATGAATG-500.2.2 CTCGGGACATTAACCG-500.2.2
#> [1,] 4.391017 4.825046
#> [2,] 4.836196 4.655617
#> [3,] 4.285337 4.556169
#> [4,] 4.174373 4.137201
#> [5,] 4.494055 4.493554
#> [6,] 4.302510 4.306630
#> [7,] 4.182299 4.077348
#> [8,] 4.932629 4.895028
#> [9,] 4.627477 4.599448
#> [10,] 4.112285 3.997238
#> [11,] 4.535007 4.413444
#> [12,] 4.611625 4.435543
#> [13,] 4.495376 4.644567
#> [14,] 4.338177 4.180479
#> [15,] 4.533686 4.469613
#> [16,] 4.480845 4.321363
#> CTCGGGAGTCTAAACC-500.2.2 CTGAAACAGGCAGTCA-500.2.2
#> [1,] 4.477528 4.217986
#> [2,] 4.071629 4.121212
#> [3,] 4.463483 4.413490
#> [4,] 4.151685 4.704790
#> [5,] 4.200843 4.360704
#> [6,] 4.463483 4.222874
#> [7,] 3.890449 4.201369
#> [8,] 4.796348 4.724340
#> [9,] 4.764045 4.914956
#> [10,] 4.168539 4.593353
#> [11,] 4.025281 4.420332
#> [12,] 4.408708 4.411535
#> [13,] 4.643258 4.488759
#> [14,] 4.407303 4.159335
#> [15,] 3.898876 4.423265
#> [16,] 4.612360 4.227761
#> CTGATCCGTAAGTTCC-500.2.2 CTTAACTCATCGGAAG-500.2.2
#> [1,] 4.464610 4.358659
#> [2,] 3.902904 4.364246
#> [3,] 4.579855 4.165363
#> [4,] 4.778584 4.240223
#> [5,] 4.463702 4.538547
#> [6,] 4.279492 4.531844
#> [7,] 4.102541 3.900559
#> [8,] 4.992740 4.728492
#> [9,] 5.461887 4.500559
#> [10,] 4.572595 4.891620
#> [11,] 4.007260 4.244693
#> [12,] 4.063521 4.489385
#> [13,] 4.233212 4.379888
#> [14,] 4.304900 4.313966
#> [15,] 4.125227 3.922905
#> [16,] 4.072595 4.313966
#> CTTAACTGTGTCGCTG-500.2.2 CTTACCGTCTGCGGCA-500.2.2
#> [1,] 4.321678 4.870043
#> [2,] 4.163636 4.170836
#> [3,] 4.584615 4.136059
#> [4,] 4.345455 3.999390
#> [5,] 4.420979 4.948139
#> [6,] 4.193007 4.100671
#> [7,] 4.248951 3.908481
#> [8,] 4.500699 5.095180
#> [9,] 4.644755 4.537523
#> [10,] 4.302098 4.340451
#> [11,] 4.444755 4.720561
#> [12,] 4.495105 4.333740
#> [13,] 4.627972 4.297132
#> [14,] 4.447552 4.108603
#> [15,] 4.209790 4.259915
#> [16,] 4.420979 4.409396
#> CTTCTCTCAGCTTCGG-500.2.2 CTTCTCTGTCTTGCGG-500.2.2
#> [1,] 4.359165 4.673537
#> [2,] 4.082712 4.012366
#> [3,] 4.760805 4.413026
#> [4,] 4.140089 4.176422
#> [5,] 4.529061 4.479802
#> [6,] 4.488077 4.831822
#> [7,] 3.897914 4.311624
#> [8,] 4.708644 4.783182
#> [9,] 4.460507 4.753504
#> [10,] 4.444113 4.589448
#> [11,] 4.715350 4.723825
#> [12,] 4.595380 4.377576
#> [13,] 4.284650 4.107172
#> [14,] 4.483607 4.434460
#> [15,] 4.300298 4.308326
#> [16,] 4.461252 4.650453
#> CTTCTCTGTGCCTGTG-500.2.2 CTTTGCGTCCGTAGGC-500.2.2
#> [1,] 4.290252 4.285094
#> [2,] 4.530120 4.234443
#> [3,] 4.329682 4.547033
#> [4,] 4.465498 4.202605
#> [5,] 4.717415 4.749638
#> [6,] 4.407448 4.244573
#> [7,] 4.061336 4.111433
#> [8,] 4.887185 4.903039
#> [9,] 4.414020 4.952243
#> [10,] 4.748083 4.219971
#> [11,] 4.366922 4.257598
#> [12,] 4.552026 4.431259
#> [13,] 4.201533 4.565847
#> [14,] 4.347207 3.973951
#> [15,] 4.672508 3.976845
#> [16,] 4.339540 4.392185
#> GAAATGAAGGTGCTAG-500.2.2 GAACATCAGTACGTTC-500.2.2
#> [1,] 4.578348 4.713131
#> [2,] 4.454416 4.283502
#> [3,] 4.776353 4.536700
#> [4,] 4.227920 4.273401
#> [5,] 4.250712 4.431650
#> [6,] 3.898860 4.783838
#> [7,] 4.253561 4.404040
#> [8,] 4.584046 4.834343
#> [9,] 4.323362 4.633670
#> [10,] 4.045584 4.428283
#> [11,] 4.494302 4.465993
#> [12,] 4.420228 4.636364
#> [13,] 4.299145 4.146801
#> [14,] 4.220798 3.935354
#> [15,] 4.286325 4.272054
#> [16,] 4.856125 4.212121
#> GAACATCGTTCAGTAC-500.2.2 GAACATCTCATGCATG-500.2.2
#> [1,] 4.353644 4.474854
#> [2,] 4.301075 4.164912
#> [3,] 4.415771 4.566082
#> [4,] 3.927121 4.390643
#> [5,] 4.450418 4.202339
#> [6,] 3.940263 4.449123
#> [7,] 4.197133 4.269006
#> [8,] 4.793309 4.974269
#> [9,] 4.130227 4.491228
#> [10,] 3.980884 4.359064
#> [11,] 4.004779 4.342690
#> [12,] 4.329749 4.652632
#> [13,] 4.416965 4.419883
#> [14,] 3.800478 4.570760
#> [15,] 4.302270 4.064327
#> [16,] 4.314217 4.534503
#> GAACCTATCCTTTCGG-500.2.2 GAACGGACAATGAATG-500.2.2
#> [1,] 4.300993 4.263331
#> [2,] 4.104660 4.128374
#> [3,] 4.414820 4.501646
#> [4,] 4.129106 4.334431
#> [5,] 4.797555 4.381172
#> [6,] 4.679144 4.172482
#> [7,] 4.291826 4.058591
#> [8,] 4.812834 4.880184
#> [9,] 4.543927 4.654378
#> [10,] 4.545455 4.178407
#> [11,] 4.834225 4.198815
#> [12,] 4.524828 4.266623
#> [13,] 4.200153 4.596445
#> [14,] 4.667685 4.192232
#> [15,] 4.200917 3.935484
#> [16,] 4.670741 4.428571
#> GACCAATCAGACGTAG-500.2.2 GACCAATGTGTTTGGT-500.2.2
#> [1,] 4.823212 4.401033
#> [2,] 4.159244 4.438898
#> [3,] 4.264507 4.604131
#> [4,] 4.232119 4.652324
#> [5,] 4.593792 4.265060
#> [6,] 4.605938 3.902754
#> [7,] 3.981107 4.221170
#> [8,] 4.950067 4.823580
#> [9,] 4.825911 4.865749
#> [10,] 4.290148 4.501721
#> [11,] 4.380567 4.123924
#> [12,] 4.290148 4.465577
#> [13,] 4.668016 4.641136
#> [14,] 4.831309 4.415663
#> [15,] 4.282051 4.265060
#> [16,] 4.364372 4.441480
#> GACCTGGCACGGTTTA-500.2.2 GACGCGTTCATTGCGA-500.2.2
#> [1,] 4.510828 4.312281
#> [2,] 4.217834 4.533333
#> [3,] 4.546497 4.618713
#> [4,] 4.217834 4.329825
#> [5,] 4.698089 4.778947
#> [6,] 4.150318 4.548538
#> [7,] 4.084076 4.102924
#> [8,] 4.695541 5.506433
#> [9,] 4.532484 4.292398
#> [10,] 4.248408 4.350877
#> [11,] 4.522293 4.845614
#> [12,] 4.356688 4.300585
#> [13,] 4.523567 4.464327
#> [14,] 4.002548 4.125146
#> [15,] 4.115924 4.091228
#> [16,] 4.606369 4.622222
#> GACGGCTTCGCAAACT-500.2.2 GACTACATCAACGGGA-500.2.2
#> [1,] 4.189081 4.215625
#> [2,] 4.177097 4.195833
#> [3,] 4.340879 4.463542
#> [4,] 4.102530 4.658333
#> [5,] 4.221039 4.453125
#> [6,] 4.315579 4.240625
#> [7,] 4.396804 4.235417
#> [8,] 4.567244 4.835417
#> [9,] 4.723036 4.869792
#> [10,] 4.173103 4.237500
#> [11,] 4.537949 4.217708
#> [12,] 4.158455 4.572917
#> [13,] 4.376831 4.543750
#> [14,] 4.292943 4.304167
#> [15,] 4.191744 4.194792
#> [16,] 4.555260 4.076042
#> GACTGCGCATCCGCGA-500.2.2 GAGGTGACAGCGTTCG-500.2.2
#> [1,] 4.481414 4.327152
#> [2,] 4.443632 4.006623
#> [3,] 4.354662 4.418543
#> [4,] 4.299208 4.333775
#> [5,] 4.391225 4.403974
#> [6,] 4.376600 4.250331
#> [7,] 4.106033 4.105960
#> [8,] 4.978672 4.860927
#> [9,] 4.901280 4.966887
#> [10,] 4.289458 4.935099
#> [11,] 4.102986 4.667550
#> [12,] 4.416819 4.243709
#> [13,] 4.607556 4.486093
#> [14,] 4.559415 4.642384
#> [15,] 3.983547 4.305960
#> [16,] 4.458257 4.101987
#> GAGGTGATCCTGCCAT-500.2.2 GATCAGTAGATTACCC-500.2.2
#> [1,] 4.222849 4.418689
#> [2,] 4.394922 4.338592
#> [3,] 4.313117 4.711165
#> [4,] 4.455571 4.156553
#> [5,] 4.671368 4.444175
#> [6,] 4.575458 4.151699
#> [7,] 4.156559 4.106796
#> [8,] 5.000000 4.712379
#> [9,] 4.538787 4.570388
#> [10,] 4.208745 4.175971
#> [11,] 3.952045 4.242718
#> [12,] 4.747532 4.473301
#> [13,] 4.521862 4.641990
#> [14,] 4.441467 4.466019
#> [15,] 4.200282 4.167476
#> [16,] 4.471086 4.236650
#> GATCAGTTCTCTGCTG-500.2.2 GATGAAATCGCGATCG-500.2.2
#> [1,] 4.467335 4.332997
#> [2,] 4.375874 4.289606
#> [3,] 4.519903 4.630676
#> [4,] 4.388332 4.215943
#> [5,] 4.633242 4.492432
#> [6,] 4.250076 4.253280
#> [7,] 4.124582 4.099899
#> [8,] 4.912185 4.909183
#> [9,] 4.892130 4.662967
#> [10,] 4.376785 4.255298
#> [11,] 4.467335 4.023209
#> [12,] 4.392890 4.183653
#> [13,] 4.403829 4.767911
#> [14,] 4.161349 4.246216
#> [15,] 4.123367 4.386478
#> [16,] 4.458827 4.235116
#> GATTCAGCAATCACAC-500.2.2 GCAAACTTCCGAATGT-500.2.2
#> [1,] 4.195858 4.595349
#> [2,] 4.189819 4.313488
#> [3,] 4.373598 4.561860
#> [4,] 5.016393 4.540465
#> [5,] 4.362381 4.922791
#> [6,] 4.332183 4.426047
#> [7,] 3.812770 4.051163
#> [8,] 4.675582 4.837209
#> [9,] 5.061260 4.528372
#> [10,] 5.037964 4.159070
#> [11,] 4.162209 4.385116
#> [12,] 4.327869 4.466047
#> [13,] 4.308887 4.455814
#> [14,] 4.603106 4.346047
#> [15,] 4.052632 4.392558
#> [16,] 3.906816 4.370233
#> GCACTCTGTCCTCTTG-500.2.2 GCATGCGGTCTTCTCG-500.2.2
#> [1,] 4.946451 4.272157
#> [2,] 3.948941 4.118431
#> [3,] 4.344956 4.949020
#> [4,] 4.236613 4.386667
#> [5,] 4.256538 4.563922
#> [6,] 4.338730 4.114510
#> [7,] 4.046077 4.090196
#> [8,] 4.869240 4.858824
#> [9,] 4.904110 4.737255
#> [10,] 4.638854 4.484706
#> [11,] 4.541719 4.368627
#> [12,] 4.230386 4.590588
#> [13,] 4.226650 4.443137
#> [14,] 4.565380 4.441569
#> [15,] 4.835616 4.492549
#> [16,] 4.626401 4.484706
#> GCATGTAGTTGTCTTT-500.2.2 GCCTCTACACGAAGCA-500.2.2
#> [1,] 4.346859 4.05125
#> [2,] 4.608639 4.09625
#> [3,] 4.641361 4.29625
#> [4,] 4.611257 4.28375
#> [5,] 4.445026 4.40500
#> [6,] 3.862565 4.56000
#> [7,] 4.215969 4.12375
#> [8,] 4.714660 4.66375
#> [9,] 4.714660 4.35000
#> [10,] 4.447644 4.32500
#> [11,] 4.407068 4.00750
#> [12,] 4.383508 4.39375
#> [13,] 4.439791 4.30625
#> [14,] 4.265707 4.97750
#> [15,] 4.566754 3.93875
#> [16,] 4.650524 4.62875
#> GCCTCTACAGTGACAG-500.2.2 GCCTCTATCTCGAGTA-500.2.2
#> [1,] 4.452685 4.759211
#> [2,] 4.378517 4.165789
#> [3,] 4.447570 4.311842
#> [4,] 4.539642 4.292763
#> [5,] 4.514066 4.460526
#> [6,] 4.354220 4.495395
#> [7,] 4.130435 3.915789
#> [8,] 4.713555 5.011842
#> [9,] 4.817136 4.656579
#> [10,] 4.597187 4.140789
#> [11,] 4.336317 4.065789
#> [12,] 4.796675 4.402632
#> [13,] 4.244246 4.423026
#> [14,] 4.421995 4.465789
#> [15,] 4.102302 4.158553
#> [16,] 4.382353 4.401316
#> GCCTCTATCTCGGACG-500.2.2 GCGACCACAGATCTGT-500.2.2
#> [1,] 4.392315 4.580587
#> [2,] 4.239636 4.441993
#> [3,] 4.185035 4.565533
#> [4,] 4.059656 4.406696
#> [5,] 4.934277 4.547625
#> [6,] 4.150657 4.465611
#> [7,] 4.047523 4.199844
#> [8,] 4.760364 4.787957
#> [9,] 4.412538 4.779652
#> [10,] 4.163802 4.479886
#> [11,] 4.190091 4.368284
#> [12,] 4.112235 4.386452
#> [13,] 4.786653 4.485336
#> [14,] 4.168857 4.341033
#> [15,] 3.935288 4.205035
#> [16,] 4.376138 4.444329
#> GCGAGAATCCTGCTTG-500.2.2 GCGCAACCACAGCGTC-500.2.2
#> [1,] 4.371703 4.392646
#> [2,] 4.372902 4.429416
#> [3,] 4.541966 4.600788
#> [4,] 4.139089 4.441234
#> [5,] 4.231415 4.557452
#> [6,] 4.519185 4.153644
#> [7,] 4.298561 4.171372
#> [8,] 5.092326 4.996717
#> [9,] 4.491607 4.435982
#> [10,] 4.589928 4.175312
#> [11,] 4.587530 4.269862
#> [12,] 4.376499 4.484570
#> [13,] 4.086331 4.430729
#> [14,] 4.382494 4.173999
#> [15,] 4.412470 4.257387
#> [16,] 4.374101 4.512804
#> GCGCAGTGTACAGTTC-500.2.2 GCGCGATAGGAGCGAG-500.2.2
#> [1,] 4.502383 4.375490
#> [2,] 4.616746 4.376471
#> [3,] 4.307692 4.160784
#> [4,] 4.200817 4.326471
#> [5,] 4.533016 4.365686
#> [6,] 4.474472 5.041176
#> [7,] 4.221920 3.897059
#> [8,] 4.909462 4.885294
#> [9,] 4.223281 4.414706
#> [10,] 4.477195 4.096078
#> [11,] 4.411164 4.172549
#> [12,] 4.493533 4.327451
#> [13,] 4.616746 4.123529
#> [14,] 3.960517 4.707843
#> [15,] 4.068074 3.991176
#> [16,] 4.383254 4.688235
#> GCTGCAGAGTGCTGCC-500.2.2 GCTGCAGTCAACCAAC-500.2.2
#> [1,] 4.532143 4.619219
#> [2,] 4.327381 4.349282
#> [3,] 4.742857 4.362041
#> [4,] 4.277381 4.493222
#> [5,] 4.525000 4.398325
#> [6,] 4.355952 4.427033
#> [7,] 4.273810 3.984051
#> [8,] 5.020238 5.148724
#> [9,] 4.672619 4.814593
#> [10,] 4.308333 4.295853
#> [11,] 4.394048 4.270734
#> [12,] 4.822619 4.397927
#> [13,] 4.515476 4.144338
#> [14,] 4.530952 4.513158
#> [15,] 4.135714 4.280702
#> [16,] 4.465476 4.374402
#> GCTGCGAAGGAGTTTA-500.2.2 GCTTCCAGTACCGAGA-500.2.2
#> [1,] 4.318182 4.227642
#> [2,] 4.332888 4.588850
#> [3,] 4.506684 4.319396
#> [4,] 4.367647 4.498258
#> [5,] 4.687166 4.425087
#> [6,] 4.148396 4.216028
#> [7,] 4.018717 4.624855
#> [8,] 4.973262 4.671312
#> [9,] 4.671123 4.574913
#> [10,] 4.235294 4.184669
#> [11,] 4.181818 4.421603
#> [12,] 4.411765 4.501742
#> [13,] 4.864973 4.229965
#> [14,] 4.295455 4.562137
#> [15,] 4.260695 4.403020
#> [16,] 4.608289 4.530778
#> GCTTGAAAGTGCCAGA-500.2.2 GCTTGAAGTTACGGAG-500.2.2
#> [1,] 4.376686 4.132837
#> [2,] 4.226397 4.317747
#> [3,] 4.742775 4.785335
#> [4,] 4.775530 4.402763
#> [5,] 4.231214 4.239107
#> [6,] 4.227360 4.128587
#> [7,] 4.461464 4.247609
#> [8,] 4.779383 4.772582
#> [9,] 4.945087 4.741764
#> [10,] 4.602119 4.300744
#> [11,] 4.512524 4.548353
#> [12,] 4.318882 4.570670
#> [13,] 4.366089 4.435707
#> [14,] 4.317919 4.334750
#> [15,] 4.205202 4.156217
#> [16,] 4.304432 4.343252
#> GGAAAGCGTGAGGGAG-500.2.2 GGAACTTAGTATCTCG-500.2.2
#> [1,] 4.606120 4.326072
#> [2,] 4.843040 4.271258
#> [3,] 4.314906 4.440618
#> [4,] 4.168806 4.231904
#> [5,] 4.056269 4.765285
#> [6,] 4.525173 4.664793
#> [7,] 4.097730 4.449754
#> [8,] 4.442251 4.860857
#> [9,] 4.220138 4.399859
#> [10,] 4.488648 4.437105
#> [11,] 4.519250 4.659171
#> [12,] 4.145114 4.527758
#> [13,] 4.535044 4.148981
#> [14,] 4.120434 4.532677
#> [15,] 4.097730 4.153900
#> [16,] 4.174729 4.589599
#> GGACAAGTCATCGATG-500.2.2 GGACAAGTCGTCTGAA-500.2.2
#> [1,] 4.511186 4.467681
#> [2,] 3.909396 4.217997
#> [3,] 4.159955 4.191381
#> [4,] 4.195749 4.495564
#> [5,] 4.357942 4.493029
#> [6,] 4.722595 4.273764
#> [7,] 4.136465 4.282636
#> [8,] 4.920582 4.382763
#> [9,] 4.616331 4.652725
#> [10,] 4.314318 4.301648
#> [11,] 4.070470 4.212928
#> [12,] 4.402685 4.461343
#> [13,] 4.691275 4.907478
#> [14,] 4.850112 4.495564
#> [15,] 3.986577 4.263625
#> [16,] 4.958613 4.351077
#> GGACAGAAGAGGGATA-500.2.2 GGACATTCAGCGATCC-500.2.2
#> [1,] 4.531288 4.408085
#> [2,] 4.598773 3.887109
#> [3,] 4.244172 4.490465
#> [4,] 4.304294 4.211289
#> [5,] 4.651534 4.475210
#> [6,] 4.310429 4.824561
#> [7,] 3.877301 4.074752
#> [8,] 5.085890 4.839054
#> [9,] 4.916564 4.700229
#> [10,] 4.555828 4.511060
#> [11,] 4.440491 4.627765
#> [12,] 4.730061 4.502670
#> [13,] 4.458896 4.005339
#> [14,] 4.185276 4.778795
#> [15,] 4.310429 4.465294
#> [16,] 4.350920 4.682685
#> GGACATTCATCCTAGA-500.2.2 GGAGCAAAGATGTGGC-500.2.2
#> [1,] 4.388462 4.595188
#> [2,] 4.593590 4.157950
#> [3,] 4.612821 4.525105
#> [4,] 4.702564 4.437238
#> [5,] 4.512821 4.880753
#> [6,] 4.465385 4.144351
#> [7,] 3.971795 3.949791
#> [8,] 5.223077 4.608787
#> [9,] 4.615385 4.876569
#> [10,] 4.261538 4.376569
#> [11,] 4.460256 4.399582
#> [12,] 4.426923 4.898536
#> [13,] 4.458974 4.718619
#> [14,] 4.084615 4.261506
#> [15,] 4.341026 4.009414
#> [16,] 4.680769 4.441423
#> GGAGCAAGTCTCTCTG-500.2.2 GGATTACCACCTCGTT-500.2.2
#> [1,] 4.377289 4.472989
#> [2,] 4.229548 4.465786
#> [3,] 4.800977 4.434574
#> [4,] 4.974359 4.735894
#> [5,] 4.462759 4.334934
#> [6,] 4.129426 4.084034
#> [7,] 4.205128 4.493397
#> [8,] 4.855922 4.587035
#> [9,] 4.642247 5.012005
#> [10,] 4.105006 4.747899
#> [11,] 4.147741 4.375750
#> [12,] 4.601954 4.308523
#> [13,] 4.402930 4.458583
#> [14,] 4.379731 4.270108
#> [15,] 4.445665 4.720288
#> [16,] 4.352869 4.194478
#> GGCAATTAGCCACGCT-500.2.2 GGCAATTAGTGTTAGA-500.2.2
#> [1,] 4.625694 4.484454
#> [2,] 4.489294 4.361533
#> [3,] 4.701824 4.969631
#> [4,] 4.359239 4.365871
#> [5,] 4.652657 4.637021
#> [6,] 4.382236 4.373102
#> [7,] 4.381443 4.191612
#> [8,] 4.713719 4.811280
#> [9,] 4.539255 4.637021
#> [10,] 4.293418 4.315257
#> [11,] 4.425059 4.464208
#> [12,] 4.544806 4.436732
#> [13,] 4.421094 4.049892
#> [14,] 4.292625 4.146059
#> [15,] 4.412371 4.367317
#> [16,] 4.344964 4.479393
#> GGCAATTTCTCACATT-500.2.2 GGCCGATCACGAGGTA-500.2.2
#> [1,] 4.611081 4.263946
#> [2,] 4.317913 4.103401
#> [3,] 4.544917 4.576871
#> [4,] 4.449166 4.234014
#> [5,] 4.519634 4.783673
#> [6,] 4.199570 4.765986
#> [7,] 4.006455 4.361905
#> [8,] 4.902636 4.861224
#> [9,] 4.846692 4.560544
#> [10,] 4.250134 4.121088
#> [11,] 4.404519 4.632653
#> [12,] 4.287789 4.497959
#> [13,] 4.316837 4.413605
#> [14,] 4.356105 4.325170
#> [15,] 4.176439 4.477551
#> [16,] 4.345885 4.250340
#> GGCGACTGTAGGCATG-500.2.2 GGCTCGAGTTTAGGAA-500.2.2
#> [1,] 4.478704 4.419655
#> [2,] 4.250926 4.204515
#> [3,] 4.687963 4.670651
#> [4,] 4.304630 4.261620
#> [5,] 4.510185 4.488712
#> [6,] 4.144444 4.524568
#> [7,] 4.502778 4.443559
#> [8,] 4.866667 4.628154
#> [9,] 4.562963 4.932271
#> [10,] 4.415741 4.168659
#> [11,] 4.517593 4.337317
#> [12,] 4.350926 4.440903
#> [13,] 4.497222 4.494024
#> [14,] 4.280556 4.302789
#> [15,] 4.138889 4.071713
#> [16,] 4.200000 4.508632
#> GGCTCGATCGCGTTTC-500.2.2 GGCTGGTCACTTCGAA-500.2.2
#> [1,] 4.098107 4.285410
#> [2,] 4.234079 4.332268
#> [3,] 4.193632 4.669862
#> [4,] 4.027539 4.230032
#> [5,] 4.544750 4.561235
#> [6,] 4.168675 4.199148
#> [7,] 3.928571 3.773163
#> [8,] 4.838210 5.167199
#> [9,] 4.540448 4.644302
#> [10,] 4.361446 4.251331
#> [11,] 4.081756 4.386581
#> [12,] 4.124785 4.401491
#> [13,] 4.576592 4.548456
#> [14,] 4.401033 4.240682
#> [15,] 3.906196 4.047923
#> [16,] 4.467298 4.458999
#> GGGAATGTCTCCGGTT-500.2.2 GGGACCTCAAGTAGTA-500.2.2
#> [1,] 4.563438 4.442918
#> [2,] 4.281037 4.213531
#> [3,] 4.592087 4.365751
#> [4,] 4.459754 4.200846
#> [5,] 4.424284 4.308668
#> [6,] 4.601637 4.143763
#> [7,] 4.169168 4.175476
#> [8,] 4.522510 4.906977
#> [9,] 4.769441 4.692389
#> [10,] 4.358799 4.383721
#> [11,] 4.240109 4.338266
#> [12,] 4.210095 4.334038
#> [13,] 4.578445 4.514799
#> [14,] 4.395634 4.155391
#> [15,] 4.350614 4.301268
#> [16,] 4.369714 4.382664
#> GGGAGATAGTGGAGTC-500.2.2 GGGAGATCAATCCGAT-500.2.2
#> [1,] 4.579178 4.594975
#> [2,] 4.237095 4.194975
#> [3,] 4.251094 4.315578
#> [4,] 4.307087 4.300503
#> [5,] 4.811024 4.512563
#> [6,] 4.329834 4.281407
#> [7,] 4.081365 3.982915
#> [8,] 5.186352 4.810050
#> [9,] 4.992126 4.776884
#> [10,] 4.057743 4.327638
#> [11,] 4.496938 4.411055
#> [12,] 4.463692 4.684422
#> [13,] 4.762030 4.401005
#> [14,] 4.300087 4.741709
#> [15,] 4.153106 4.141709
#> [16,] 4.424322 4.539698
#> GGGAGATTCATTCACT-500.2.2 GGGTTGCAGCAGCCTC-500.2.2
#> [1,] 4.413428 4.571087
#> [2,] 4.210836 4.663082
#> [3,] 4.730271 4.338112
#> [4,] 4.645465 4.437276
#> [5,] 4.343934 4.462366
#> [6,] 3.984688 4.095579
#> [7,] 4.293286 3.984468
#> [8,] 4.723204 4.647551
#> [9,] 5.148410 4.762246
#> [10,] 4.431095 4.218638
#> [11,] 4.203769 4.167264
#> [12,] 4.441696 4.369176
#> [13,] 4.454653 4.671446
#> [14,] 4.285041 4.303465
#> [15,] 4.234393 4.193548
#> [16,] 4.571260 4.170848
#> GGGTTGCAGTACTTGC-500.2.2 GGGTTGCGTCACTTCC-500.2.2
#> [1,] 4.654275 4.214161
#> [2,] 4.066914 4.485140
#> [3,] 4.493494 4.589161
#> [4,] 4.154275 4.491259
#> [5,] 4.706320 4.638986
#> [6,] 4.897770 4.478147
#> [7,] 4.144052 4.391608
#> [8,] 4.699814 4.788462
#> [9,] 4.719331 4.722902
#> [10,] 4.309480 4.196678
#> [11,] 4.737918 4.430070
#> [12,] 4.451673 4.724650
#> [13,] 4.052974 4.347028
#> [14,] 4.476766 4.470280
#> [15,] 4.264870 4.159091
#> [16,] 4.552045 4.513112
#> GTAACGTGTCATCCCT-500.2.2 GTACTCCAGATCGATA-500.2.2
#> [1,] 4.242595 4.008499
#> [2,] 4.087447 4.171388
#> [3,] 4.057828 4.484419
#> [4,] 3.953456 4.315864
#> [5,] 4.169252 4.412181
#> [6,] 5.331453 4.477337
#> [7,] 3.966150 4.058074
#> [8,] 4.564175 5.079320
#> [9,] 4.600846 3.937677
#> [10,] 4.196051 4.402266
#> [11,] 3.908322 4.415014
#> [12,] 4.344147 4.195467
#> [13,] 4.184767 4.398017
#> [14,] 5.011283 4.308782
#> [15,] 4.132581 4.215297
#> [16,] 4.768688 4.594901
#> GTACTCCGTCTAGTGT-500.2.2 GTACTCCTCTGGCGAC-500.2.2
#> [1,] 4.445021 4.550388
#> [2,] 4.437759 4.081949
#> [3,] 4.362033 4.578073
#> [4,] 4.350622 4.590255
#> [5,] 4.345436 4.406423
#> [6,] 4.449170 4.495017
#> [7,] 3.930498 4.307863
#> [8,] 4.782158 5.161683
#> [9,] 4.847510 4.280177
#> [10,] 4.423237 4.282392
#> [11,] 4.046680 4.722038
#> [12,] 4.396266 4.547065
#> [13,] 4.729253 4.581395
#> [14,] 4.179461 4.358804
#> [15,] 4.158714 4.114064
#> [16,] 4.516598 4.203765
#> GTACTTTAGATCCCGC-500.2.2 GTAGGCCGTACGCACC-500.2.2
#> [1,] 4.536336 4.330189
#> [2,] 4.541453 3.855795
#> [3,] 4.516888 4.733154
#> [4,] 4.318321 4.229111
#> [5,] 4.427840 4.252022
#> [6,] 4.251791 4.846361
#> [7,] 4.162743 3.873315
#> [8,] 5.077789 5.037736
#> [9,] 4.472876 4.677898
#> [10,] 4.520983 4.202156
#> [11,] 4.340839 4.150943
#> [12,] 4.470829 4.580863
#> [13,] 4.435005 4.443396
#> [14,] 4.153531 4.772237
#> [15,] 4.364381 4.194070
#> [16,] 4.232344 4.669811
#> GTAGTCAAGTCCTCCT-500.2.2 GTAGTCACACCCATTC-500.2.2
#> [1,] 4.348432 4.376588
#> [2,] 4.128920 4.518603
#> [3,] 4.229965 4.621143
#> [4,] 4.160279 4.451452
#> [5,] 4.167247 4.693285
#> [6,] 4.745645 4.361162
#> [7,] 3.934959 4.291289
#> [8,] 4.552846 4.856624
#> [9,] 4.458769 4.542196
#> [10,] 3.888502 4.383848
#> [11,] 4.141696 4.294918
#> [12,] 4.454123 4.710526
#> [13,] 4.105691 4.332577
#> [14,] 4.902439 4.363430
#> [15,] 4.225319 4.333031
#> [16,] 4.829268 4.728221
#> GTATTCTGTTGCGTTA-500.2.2 GTCAAGTAGACCGGAT-500.2.2
#> [1,] 4.382114 4.643077
#> [2,] 4.390244 4.333333
#> [3,] 4.398374 4.353846
#> [4,] 4.490128 4.394872
#> [5,] 4.298490 4.501538
#> [6,] 4.484321 4.126154
#> [7,] 3.937282 4.325128
#> [8,] 4.475029 4.907692
#> [9,] 5.008130 4.491282
#> [10,] 4.620209 4.580513
#> [11,] 4.211382 4.183590
#> [12,] 4.396051 4.612308
#> [13,] 4.372822 4.785641
#> [14,] 4.091754 4.461538
#> [15,] 4.624855 4.145641
#> [16,] 4.348432 4.256410
#> GTCACAAGTGAGTGAC-500.2.2 GTCATTTCAGCTTCGG-500.2.2
#> [1,] 4.524712 4.109934
#> [2,] 4.415030 4.316556
#> [3,] 4.597156 4.442384
#> [4,] 4.466486 4.712583
#> [5,] 4.720379 4.352318
#> [6,] 4.157752 4.229139
#> [7,] 4.339201 4.241060
#> [8,] 4.905890 4.570861
#> [9,] 4.320244 4.267550
#> [10,] 4.259986 4.214570
#> [11,] 4.417739 4.468874
#> [12,] 4.534191 4.505960
#> [13,] 4.560596 4.482119
#> [14,] 4.218687 4.576159
#> [15,] 4.188219 4.254305
#> [16,] 4.327014 4.312583
#> GTCCTCATCATGCATG-500.2.2 GTCGGGTTCGTCGTTC-500.2.2
#> [1,] 4.375848 4.561710
#> [2,] 4.322931 4.055394
#> [3,] 4.371777 4.616132
#> [4,] 4.466757 4.103984
#> [5,] 4.438263 4.608358
#> [6,] 3.994573 4.706511
#> [7,] 4.248304 4.369291
#> [8,] 4.801900 4.811467
#> [9,] 5.293080 4.502430
#> [10,] 4.111262 4.291545
#> [11,] 4.166893 4.551992
#> [12,] 4.312076 4.651118
#> [13,] 3.993216 3.989310
#> [14,] 4.468114 4.366375
#> [15,] 4.184532 4.331390
#> [16,] 4.260516 4.454810
#> GTCGTAAAGACAAGCC-500.2.2 GTCGTAAAGTAGCCGA-500.2.2
#> [1,] 4.263923 4.236647
#> [2,] 4.097659 4.245686
#> [3,] 4.782889 4.663106
#> [4,] 4.871671 4.276910
#> [5,] 4.581921 4.283484
#> [6,] 4.241324 4.451109
#> [7,] 3.903955 4.447823
#> [8,] 5.087167 4.769104
#> [9,] 5.445521 4.901397
#> [10,] 4.781275 4.491372
#> [11,] 4.153349 4.375514
#> [12,] 4.097659 4.627773
#> [13,] 4.215496 4.291701
#> [14,] 4.281679 4.228431
#> [15,] 4.208232 4.442892
#> [16,] 4.378531 4.169269
#> GTGCATAAGATCCCGC-500.2.2 GTGCTTCTCTCCTATA-500.2.2
#> [1,] 4.496344 4.357569
#> [2,] 4.529651 4.655542
#> [3,] 4.588140 4.470799
#> [4,] 4.771730 4.387366
#> [5,] 4.640942 4.239571
#> [6,] 4.185215 4.246722
#> [7,] 4.316816 4.379023
#> [8,] 4.687246 4.938021
#> [9,] 4.437855 5.061979
#> [10,] 4.562145 4.680572
#> [11,] 4.304630 4.315852
#> [12,] 4.449228 4.510131
#> [13,] 4.773355 4.241955
#> [14,] 4.030057 4.491061
#> [15,] 4.294882 4.586412
#> [16,] 4.065800 4.209774
#> GTGTTAGAGAAGGCCT-500.2.2 GTGTTAGTCAGTCAGT-500.2.2
#> [1,] 4.237589 4.317680
#> [2,] 4.595745 4.258287
#> [3,] 4.687943 4.343923
#> [4,] 4.231678 4.359116
#> [5,] 4.450355 4.309392
#> [6,] 4.326241 4.205801
#> [7,] 4.203310 4.190608
#> [8,] 4.884161 5.092541
#> [9,] 4.391253 4.779006
#> [10,] 4.674941 4.401934
#> [11,] 4.141844 4.453039
#> [12,] 4.191489 4.178177
#> [13,] 4.358156 4.219613
#> [14,] 4.170213 4.277624
#> [15,] 4.276596 4.125691
#> [16,] 4.313239 4.551105
#> GTGTTAGTCCGAATGT-500.2.2 GTTAAGCCACTGTCGG-500.2.2
#> [1,] 4.437500 4.387141
#> [2,] 4.495739 4.868673
#> [3,] 4.336648 4.536252
#> [4,] 4.765625 4.693570
#> [5,] 4.200284 4.335157
#> [6,] 4.393466 4.046512
#> [7,] 4.204545 3.932969
#> [8,] 4.632102 4.534884
#> [9,] 4.274148 4.664843
#> [10,] 4.312500 4.292750
#> [11,] 4.052557 4.254446
#> [12,] 4.521307 4.421341
#> [13,] 4.642045 4.135431
#> [14,] 4.359375 4.429549
#> [15,] 4.008523 4.228454
#> [16,] 4.082386 4.218878
#> GTTCATTGTCTCTTTA-500.2.2 GTTCATTTCGTAGATC-500.2.2
#> [1,] 4.688764 4.714423
#> [2,] 4.065169 4.735985
#> [3,] 4.713483 4.301390
#> [4,] 4.450562 4.402012
#> [5,] 4.864045 4.498802
#> [6,] 4.314607 4.599425
#> [7,] 4.070787 4.065644
#> [8,] 5.015730 4.717298
#> [9,] 4.771910 4.584571
#> [10,] 4.212360 4.591759
#> [11,] 4.365169 4.568280
#> [12,] 4.658427 4.508864
#> [13,] 4.625843 4.320077
#> [14,] 4.276404 4.416387
#> [15,] 4.066292 4.170101
#> [16,] 4.335955 4.254911
#> GTTCGGGTCCAGTAGT-500.2.2 TAAACCGGTCGGCACT-500.2.2
#> [1,] 4.500647 4.364706
#> [2,] 3.940492 4.470588
#> [3,] 4.507115 4.356863
#> [4,] 4.631307 4.558170
#> [5,] 4.411384 4.154248
#> [6,] 4.213454 4.494118
#> [7,] 4.001294 4.048366
#> [8,] 4.821475 4.546405
#> [9,] 5.072445 4.567320
#> [10,] 4.786546 4.334641
#> [11,] 4.219922 4.247059
#> [12,] 4.403622 4.454902
#> [13,] 4.148771 4.313725
#> [14,] 4.380336 4.355556
#> [15,] 4.355757 4.533333
#> [16,] 4.236740 4.398693
#> TAAACCGGTCTGATCA-500.2.2 TAAGAGAGTCTTCAAG-500.2.2
#> [1,] 4.434914 4.533869
#> [2,] 3.955600 4.203215
#> [3,] 4.338042 4.743972
#> [4,] 5.045409 4.657865
#> [5,] 4.116044 4.471871
#> [6,] 4.367306 4.211251
#> [7,] 3.972755 4.414466
#> [8,] 5.557013 4.494834
#> [9,] 5.309788 5.030999
#> [10,] 4.725530 4.299656
#> [11,] 4.269425 4.319173
#> [12,] 4.078708 4.575201
#> [13,] 3.992936 4.202067
#> [14,] 4.031282 4.198622
#> [15,] 4.409687 4.291619
#> [16,] 4.324924 4.500574
#> TAAGCGTTCGTTTATC-500.2.2 TAAGTGCCAGCTCGAC-500.2.2
#> [1,] 4.598007 4.308982
#> [2,] 4.646733 4.486228
#> [3,] 4.511628 4.468263
#> [4,] 4.405316 4.536527
#> [5,] 4.150609 4.585629
#> [6,] 4.232558 4.246707
#> [7,] 4.140642 4.013174
#> [8,] 4.521595 4.673054
#> [9,] 4.939092 5.086228
#> [10,] 4.929125 4.402395
#> [11,] 4.501661 4.177246
#> [12,] 4.506091 4.639521
#> [13,] 4.600221 4.476647
#> [14,] 4.508306 4.186826
#> [15,] 4.481728 4.231138
#> [16,] 4.266888 4.341317
#> TACAGTGCATTACGAC-500.2.2 TACGGGCTCACTCTTA-500.2.2
#> [1,] 4.573904 4.264858
#> [2,] 4.376147 4.177003
#> [3,] 4.170234 4.333333
#> [4,] 4.400612 4.332041
#> [5,] 4.539246 4.642119
#> [6,] 4.347604 4.228682
#> [7,] 4.204893 4.149871
#> [8,] 4.628950 4.701550
#> [9,] 4.621814 4.342377
#> [10,] 4.232416 4.228682
#> [11,] 4.474006 4.202842
#> [12,] 4.591233 4.310078
#> [13,] 4.426096 4.811370
#> [14,] 4.252803 4.512920
#> [15,] 4.233435 3.667959
#> [16,] 4.355759 4.237726
#> TACGGTAGTACCGAGA-500.2.2 TACTCGCTCCAGGGCT-500.2.2
#> [1,] 4.360000 4.669619
#> [2,] 4.333333 4.509300
#> [3,] 4.396364 4.550930
#> [4,] 4.424242 4.026572
#> [5,] 4.269091 4.679362
#> [6,] 4.408485 3.730735
#> [7,] 4.390303 4.255979
#> [8,] 4.773333 4.425155
#> [9,] 4.736970 4.357839
#> [10,] 4.248485 4.223206
#> [11,] 4.029091 4.160319
#> [12,] 4.020606 4.397697
#> [13,] 4.374545 4.566873
#> [14,] 4.430303 3.968113
#> [15,] 4.295758 4.364925
#> [16,] 4.317576 4.516386
#> TACTTGTAGGGTCTCC-500.2.2 TACTTGTTCATACGGT-500.2.2
#> [1,] 4.631513 4.592053
#> [2,] 4.526679 4.415894
#> [3,] 4.309479 4.568212
#> [4,] 4.516008 4.540397
#> [5,] 4.706842 4.521854
#> [6,] 4.478970 4.260927
#> [7,] 3.987445 3.891391
#> [8,] 4.988701 5.113907
#> [9,] 4.618330 5.038411
#> [10,] 4.326428 4.385430
#> [11,] 4.234149 4.207947
#> [12,] 4.478970 4.535099
#> [13,] 4.674827 4.760265
#> [14,] 4.259887 4.646358
#> [15,] 3.923415 4.139073
#> [16,] 4.305085 4.188079
#> TAGAGCTCAGCGATCC-500.2.2 TAGGCATCAAAGGAAG-500.2.2
#> [1,] 4.465024 4.275472
#> [2,] 3.993641 4.056604
#> [3,] 4.802067 4.383648
#> [4,] 4.193164 4.272956
#> [5,] 4.534976 4.586164
#> [6,] 4.679650 4.690566
#> [7,] 4.432432 4.286792
#> [8,] 4.499205 4.715723
#> [9,] 4.751987 4.626415
#> [10,] 4.302862 4.358491
#> [11,] 4.536566 4.085535
#> [12,] 4.444356 4.242767
#> [13,] 4.023052 4.384906
#> [14,] 4.586645 4.569811
#> [15,] 4.100954 4.143396
#> [16,] 4.581876 4.872956
#> TAGGCATTCGACCAGC-500.2.2 TAGTGGTGTAAACCTC-500.2.2
#> [1,] 4.291667 4.493947
#> [2,] 4.176587 4.371842
#> [3,] 4.471230 4.294474
#> [4,] 4.246032 4.225526
#> [5,] 4.370040 4.364211
#> [6,] 4.239087 4.209211
#> [7,] 4.038690 4.036053
#> [8,] 4.960317 4.812632
#> [9,] 4.634921 4.657105
#> [10,] 4.432540 4.290263
#> [11,] 4.618056 4.371579
#> [12,] 4.219246 4.438684
#> [13,] 4.376984 4.705789
#> [14,] 4.328373 4.389474
#> [15,] 4.361111 4.155000
#> [16,] 4.385913 4.360263
#> TAGTGGTTCGTGACAT-500.2.2 TAGTTGGCACACGCTG-500.2.2
#> [1,] 4.472986 4.336420
#> [2,] 4.332227 4.514403
#> [3,] 4.646919 4.695473
#> [4,] 4.261611 4.376543
#> [5,] 4.494313 4.337449
#> [6,] 4.567299 4.431070
#> [7,] 4.149763 4.477366
#> [8,] 4.757820 4.851852
#> [9,] 4.577251 4.614198
#> [10,] 4.339336 4.467078
#> [11,] 4.122749 4.233539
#> [12,] 4.512796 4.641975
#> [13,] 4.485308 4.473251
#> [14,] 4.325118 4.328189
#> [15,] 4.259716 4.491770
#> [16,] 4.657820 4.506173
#> TATCAGGAGTCTCCTC-500.2.2 TATCTCAGTGCAACGA-500.2.2
#> [1,] 4.500000 4.410673
#> [2,] 4.393878 4.620650
#> [3,] 4.488776 4.346868
#> [4,] 4.306122 4.141531
#> [5,] 4.687755 4.533643
#> [6,] 4.335714 4.357309
#> [7,] 4.343878 4.216937
#> [8,] 4.941837 4.871230
#> [9,] 4.628571 4.759861
#> [10,] 4.621429 4.407193
#> [11,] 4.787755 4.508121
#> [12,] 4.868367 4.370070
#> [13,] 4.481633 4.482599
#> [14,] 4.385714 4.495360
#> [15,] 4.355102 3.964037
#> [16,] 4.282653 4.486079
#> TATGCCCAGTGTCCCG-500.2.2 TATTACCAGGAGCGTT-500.2.2
#> [1,] 4.463197 4.444343
#> [2,] 4.417455 4.170620
#> [3,] 4.520505 4.508212
#> [4,] 4.413775 4.322993
#> [5,] 4.403260 4.633212
#> [6,] 4.267613 4.281022
#> [7,] 4.055205 3.956204
#> [8,] 4.939537 4.889599
#> [9,] 4.734490 4.644161
#> [10,] 4.238170 4.104927
#> [11,] 4.234490 4.235401
#> [12,] 4.432177 4.088504
#> [13,] 4.330179 4.580292
#> [14,] 4.199790 4.197080
#> [15,] 4.245005 3.990876
#> [16,] 4.387487 4.464416
#> TCAACGACACCGAATT-500.2.2 TCAACGAGTTGCGCAC-500.2.2
#> [1,] 4.450560 4.375434
#> [2,] 4.171642 4.379598
#> [3,] 4.578358 4.546149
#> [4,] 4.148321 4.247745
#> [5,] 4.877799 4.779320
#> [6,] 4.756530 4.877169
#> [7,] 4.287313 4.132547
#> [8,] 4.753731 5.043720
#> [9,] 4.739739 4.637752
#> [10,] 4.543843 4.524636
#> [11,] 4.741604 4.689105
#> [12,] 4.501866 4.464955
#> [13,] 3.676306 4.198473
#> [14,] 4.679104 4.446912
#> [15,] 4.287313 4.417071
#> [16,] 4.579291 4.764747
#> TCACAAGTCGTTGACA-500.2.2 TCAGATGAGCTCCTTC-500.2.2
#> [1,] 4.522727 4.525586
#> [2,] 4.441700 4.294243
#> [3,] 4.526680 4.531983
#> [4,] 4.451581 4.383795
#> [5,] 4.485178 4.859275
#> [6,] 4.431818 4.350746
#> [7,] 4.249012 4.323028
#> [8,] 4.651186 4.733475
#> [9,] 4.673913 4.769723
#> [10,] 4.518775 3.987207
#> [11,] 4.227273 4.179104
#> [12,] 4.224308 4.157783
#> [13,] 4.387352 4.899787
#> [14,] 4.079051 4.104478
#> [15,] 4.493083 3.934968
#> [16,] 4.578063 4.324094
#> TCAGATGGTCTCTTTA-500.2.2 TCAGCAACAGCATGAG-500.2.2
#> [1,] 4.400612 4.546689
#> [2,] 4.407747 4.379457
#> [3,] 4.635066 4.419355
#> [4,] 4.586137 4.561121
#> [5,] 4.294597 4.351443
#> [6,] 4.101937 4.267402
#> [7,] 4.329256 3.768251
#> [8,] 5.199796 5.488964
#> [9,] 4.510703 5.229202
#> [10,] 4.180428 4.522071
#> [11,] 4.345566 4.259762
#> [12,] 4.481142 4.184211
#> [13,] 4.289501 4.361630
#> [14,] 4.239551 4.371817
#> [15,] 4.226300 4.129032
#> [16,] 4.092762 4.286927
#> TCAGGTAGTGTTCGAT-500.2.2 TCATTACCATCGGTTA-500.2.2
#> [1,] 4.301863 4.527841
#> [2,] 4.173913 4.504195
#> [3,] 4.424845 4.399695
#> [4,] 4.050932 4.306636
#> [5,] 4.385093 4.762777
#> [6,] 4.191304 4.363082
#> [7,] 4.057143 4.128146
#> [8,] 4.629814 4.573608
#> [9,] 4.863354 4.617849
#> [10,] 4.257143 4.181541
#> [11,] 4.232298 4.138825
#> [12,] 4.412422 4.423341
#> [13,] 4.401242 4.463768
#> [14,] 4.125466 3.976354
#> [15,] 4.530435 4.006865
#> [16,] 4.406211 4.649886
#> TCATTTGTCTGATACG-500.2.2 TCCACACTCTTGGGTA-500.2.2
#> [1,] 4.929961 4.722184
#> [2,] 3.696498 4.642709
#> [3,] 4.346304 4.527298
#> [4,] 4.145081 4.211472
#> [5,] 4.695386 4.549413
#> [6,] 3.772651 4.861092
#> [7,] 4.309616 4.143746
#> [8,] 4.158421 4.599862
#> [9,] 4.147860 4.668970
#> [10,] 3.879933 4.133379
#> [11,] 4.053919 4.152730
#> [12,] 4.220122 4.818245
#> [13,] 4.287382 4.308915
#> [14,] 4.046693 4.272287
#> [15,] 4.362424 3.950933
#> [16,] 4.197888 4.158950
#> TCGAGGCAGACTACAA-500.2.2 TCGAGGCCACAGTCGC-500.2.2
#> [1,] 4.511327 4.138480
#> [2,] 4.477886 4.246324
#> [3,] 4.323625 4.444853
#> [4,] 4.349515 4.800245
#> [5,] 4.734628 4.523284
#> [6,] 4.382956 4.495098
#> [7,] 4.127292 4.235294
#> [8,] 5.059331 4.922794
#> [9,] 4.792880 4.366422
#> [10,] 4.129450 4.409314
#> [11,] 4.211435 4.317402
#> [12,] 4.554477 4.308824
#> [13,] 4.670982 4.117647
#> [14,] 3.818770 4.436275
#> [15,] 4.317152 4.395833
#> [16,] 4.558792 4.129902
#> TCGCGTTCACAAGCCC-500.2.2 TCGGTAAGTCTCTCTG-500.2.2
#> [1,] 3.918654 4.128099
#> [2,] 4.489481 4.547934
#> [3,] 4.757363 4.414050
#> [4,] 4.164095 4.728926
#> [5,] 5.053296 4.510744
#> [6,] 4.458626 4.500826
#> [7,] 4.350631 3.745455
#> [8,] 5.154278 5.050413
#> [9,] 4.330996 4.732231
#> [10,] 4.172511 4.390083
#> [11,] 4.932679 4.547934
#> [12,] 4.354839 4.492562
#> [13,] 4.448808 4.187603
#> [14,] 4.158485 4.349587
#> [15,] 4.270687 4.372727
#> [16,] 4.690042 4.295041
#> TCGTACCCAAGTAATG-500.2.2 TCTCATACAAGAGGCT-500.2.2
#> [1,] 4.206633 4.328720
#> [2,] 4.214286 4.018454
#> [3,] 4.234694 4.596309
#> [4,] 4.389031 4.177624
#> [5,] 4.610969 4.667820
#> [6,] 4.140306 4.231834
#> [7,] 4.325255 4.297578
#> [8,] 4.616071 4.528258
#> [9,] 4.603316 4.431373
#> [10,] 4.209184 4.391003
#> [11,] 4.183673 4.876586
#> [12,] 4.429847 4.452134
#> [13,] 4.765306 4.329873
#> [14,] 4.545918 4.547866
#> [15,] 3.896684 3.855825
#> [16,] 4.306122 4.561707
#> TCTCTAAGTCACACGC-500.2.2 TCTGGAACAATGAAAC-500.2.2
#> [1,] 4.398297 4.313142
#> [2,] 4.257332 4.373175
#> [3,] 4.720908 4.237426
#> [4,] 4.020814 4.657653
#> [5,] 4.650899 4.325041
#> [6,] 4.010407 4.374256
#> [7,] 4.208136 4.252028
#> [8,] 4.349101 4.809627
#> [9,] 3.977294 4.776636
#> [10,] 4.334910 4.499730
#> [11,] 4.120151 4.422390
#> [12,] 4.611164 4.432125
#> [13,] 4.463576 4.346674
#> [14,] 3.916746 4.519740
#> [15,] 4.575213 4.250946
#> [16,] 4.596026 4.284478
#> TCTTCGGCAAGCCGTC-500.2.2 TCTTCGGGTGCGGTAA-500.2.2
#> [1,] 4.012061 4.448315
#> [2,] 4.299342 4.410112
#> [3,] 4.640351 4.370787
#> [4,] 4.331140 4.269663
#> [5,] 4.617325 4.507865
#> [6,] 4.628289 4.496629
#> [7,] 4.401316 4.355056
#> [8,] 4.771930 4.939326
#> [9,] 4.630482 4.516854
#> [10,] 4.289474 4.507865
#> [11,] 4.399123 4.133708
#> [12,] 4.582237 4.664045
#> [13,] 4.183114 4.415730
#> [14,] 4.097588 4.498876
#> [15,] 4.640351 4.011236
#> [16,] 4.413377 4.624719
#> TCTTCGGTCCTTGACC-500.2.2 TGACAACGTACGCACC-500.2.2
#> [1,] 4.450094 4.452166
#> [2,] 4.526365 4.388087
#> [3,] 4.674200 4.615523
#> [4,] 4.589454 4.353791
#> [5,] 4.660075 4.611011
#> [6,] 4.216573 4.137184
#> [7,] 4.467985 4.183213
#> [8,] 4.590395 4.764440
#> [9,] 4.419021 4.877256
#> [10,] 4.471751 4.465704
#> [11,] 4.549906 4.352888
#> [12,] 4.624294 4.618231
#> [13,] 4.467043 4.457581
#> [14,] 4.172316 4.120036
#> [15,] 4.314501 4.166968
#> [16,] 4.296610 4.492780
#> TGACAACGTTGCTCCT-500.2.2 TGACAACGTTTGACAC-500.2.2
#> [1,] 4.304265 4.505794
#> [2,] 4.436019 4.211997
#> [3,] 4.725118 4.805726
#> [4,] 4.188626 4.175869
#> [5,] 4.186730 4.616224
#> [6,] 4.434123 4.639400
#> [7,] 4.362085 4.220859
#> [8,] 4.907109 4.789366
#> [9,] 4.717536 4.432856
#> [10,] 4.448341 4.497614
#> [11,] 4.221801 4.885481
#> [12,] 4.690047 4.513974
#> [13,] 4.341232 4.130198
#> [14,] 4.270142 4.749148
#> [15,] 4.179147 4.323108
#> [16,] 4.380095 4.588957
#> TGAGCCGGTCTCGTTC-500.2.2 TGCCAAACAGACAAAT-500.2.2
#> [1,] 4.590864 4.203617
#> [2,] 4.353525 4.471412
#> [3,] 4.606753 4.601517
#> [4,] 4.308838 4.479580
#> [5,] 4.323734 4.943991
#> [6,] 4.285005 4.534422
#> [7,] 4.216485 4.206534
#> [8,] 4.828203 4.949242
#> [9,] 4.886792 4.417736
#> [10,] 4.594836 4.565344
#> [11,] 4.277061 4.821470
#> [12,] 4.476663 4.184364
#> [13,] 4.554121 4.410735
#> [14,] 4.408143 4.461494
#> [15,] 4.523337 4.117270
#> [16,] 4.252234 4.354142
#> TGCCCTATCATGCAAC-500.2.2 TGCGGGTTCTCATTCA-500.2.2
#> [1,] 4.404851 4.364592
#> [2,] 4.013993 4.398949
#> [3,] 4.495336 4.427243
#> [4,] 4.138993 4.327809
#> [5,] 4.575560 4.502021
#> [6,] 4.864739 4.294260
#> [7,] 3.997201 4.263137
#> [8,] 5.017724 4.820129
#> [9,] 4.698694 4.603880
#> [10,] 4.545709 4.195230
#> [11,] 4.377799 4.444220
#> [12,] 4.664179 4.408246
#> [13,] 4.393657 4.333872
#> [14,] 4.411381 4.305174
#> [15,] 4.281716 4.278901
#> [16,] 4.209888 4.778496
#> TGCTACCAGTGTCCCG-500.2.2 TGCTACCCAACAACCT-500.2.2
#> [1,] 4.418667 4.424658
#> [2,] 4.196000 4.356970
#> [3,] 4.557333 4.520548
#> [4,] 4.648000 4.373892
#> [5,] 4.217333 4.518131
#> [6,] 3.882667 4.510073
#> [7,] 4.193333 4.793715
#> [8,] 4.964000 4.770346
#> [9,] 4.981333 4.637389
#> [10,] 4.416000 4.534247
#> [11,] 4.586667 4.410153
#> [12,] 4.252000 4.661563
#> [13,] 4.138667 4.382756
#> [14,] 4.550667 4.197421
#> [15,] 4.320000 4.493956
#> [16,] 4.513333 4.153908
#> TGGACGCCACGAGGTA-500.2.2 TGGTTAGAGGAATTAC-500.2.2
#> [1,] 4.473629 4.655653
#> [2,] 4.251055 4.324523
#> [3,] 4.151899 4.280470
#> [4,] 4.287975 4.154185
#> [5,] 4.866034 4.298091
#> [6,] 4.159283 4.265786
#> [7,] 4.120253 4.093979
#> [8,] 5.051688 4.797357
#> [9,] 4.539030 4.835536
#> [10,] 4.031646 4.279001
#> [11,] 4.280591 4.077093
#> [12,] 4.217300 4.222467
#> [13,] 4.806962 4.542584
#> [14,] 4.137131 4.501468
#> [15,] 4.274262 4.229809
#> [16,] 4.220464 4.123348
#> TGTATTCCATGCTAGT-500.2.2 TGTCCCACAAAGCGGT-500.2.2
#> [1,] 4.386231 4.434612
#> [2,] 4.297550 4.106500
#> [3,] 4.646441 4.089272
#> [4,] 4.246208 4.186374
#> [5,] 4.565928 4.639781
#> [6,] 4.366394 3.996868
#> [7,] 4.234539 4.205168
#> [8,] 4.441074 4.934221
#> [9,] 4.831972 4.605325
#> [10,] 4.033839 4.184025
#> [11,] 4.278880 4.374315
#> [12,] 4.341890 4.474550
#> [13,] 4.371062 4.955364
#> [14,] 4.499417 4.227095
#> [15,] 4.270712 3.949099
#> [16,] 4.683781 4.507439
#> TGTTCCGTCTACTTAC-500.2.2 TTAACTCGTAATCACC-500.2.2
#> [1,] 4.712375 4.293586
#> [2,] 4.276477 4.343750
#> [3,] 4.496098 4.684211
#> [4,] 4.613155 4.345395
#> [5,] 4.448161 4.274671
#> [6,] 4.190635 4.282895
#> [7,] 4.499443 4.090461
#> [8,] 4.651059 4.962993
#> [9,] 4.511706 4.804276
#> [10,] 4.092531 4.583059
#> [11,] 4.494983 4.191612
#> [12,] 4.405797 4.353618
#> [13,] 4.387960 4.375822
#> [14,] 3.974359 4.106086
#> [15,] 4.580825 4.065789
#> [16,] 4.296544 4.330592
#> TTAACTCTCGGAGCAA-500.2.2 TTAGGACGTATCTGCA-500.2.2
#> [1,] 4.589226 5.075255
#> [2,] 4.017677 4.989796
#> [3,] 4.391414 4.663265
#> [4,] 4.405724 4.020408
#> [5,] 4.429293 4.331633
#> [6,] 4.297980 4.658163
#> [7,] 3.947811 4.258929
#> [8,] 5.228956 4.580357
#> [9,] 5.069024 4.195153
#> [10,] 4.235690 4.914541
#> [11,] 4.188552 4.552296
#> [12,] 4.121212 4.538265
#> [13,] 4.472222 4.318878
#> [14,] 4.204545 4.136480
#> [15,] 3.985690 3.635204
#> [16,] 4.404040 4.007653
#> TTCGAAGTCATTATCC-500.2.2 TTCGGTCAGCAATCTC-500.2.2
#> [1,] 4.627604 4.329679
#> [2,] 4.402344 4.224745
#> [3,] 4.609375 4.534847
#> [4,] 4.533854 4.452623
#> [5,] 4.640625 4.476899
#> [6,] 4.257812 4.477682
#> [7,] 3.906250 4.474550
#> [8,] 4.714844 4.578700
#> [9,] 4.540365 4.740799
#> [10,] 4.322917 4.321065
#> [11,] 4.210938 4.291308
#> [12,] 4.451823 4.595145
#> [13,] 4.800781 4.288175
#> [14,] 4.265625 4.403289
#> [15,] 4.079427 4.281128
#> [16,] 4.276042 4.324980
#> TTCTACAAGAGACTTA-500.2.2 TTCTACACAGGTCGTC-500.2.2
#> [1,] 4.628003 4.307692
#> [2,] 4.198012 4.120239
#> [3,] 4.304060 4.616131
#> [4,] 4.083679 4.280060
#> [5,] 4.893123 4.601942
#> [6,] 3.946976 4.492905
#> [7,] 4.533554 4.286034
#> [8,] 4.284176 4.602689
#> [9,] 3.957746 4.485437
#> [10,] 4.037283 4.295743
#> [11,] 4.205468 4.941001
#> [12,] 4.024027 4.415982
#> [13,] 4.275062 4.057506
#> [14,] 4.220381 4.666916
#> [15,] 4.251864 4.337565
#> [16,] 4.502900 4.464526
#> TTCTACAGTACCGTTA-500.2.2 TTCTACAGTTTGTTTC-500.2.2
#> [1,] 4.280053 4.820823
#> [2,] 4.684280 5.412833
#> [3,] 4.785997 4.427361
#> [4,] 4.445178 4.225182
#> [5,] 4.701453 4.223971
#> [6,] 4.132100 4.904358
#> [7,] 4.003963 4.168281
#> [8,] 4.544254 4.401937
#> [9,] 4.484808 4.102906
#> [10,] 4.418758 4.272397
#> [11,] 4.582563 4.734867
#> [12,] 4.451783 4.976998
#> [13,] 4.877147 4.371671
#> [14,] 4.210040 4.194915
#> [15,] 4.215324 3.869249
#> [16,] 4.845443 4.029056
#> TTCTCAATCTTTCCTC-500.2.2 TTCTCCTAGTACGACG-500.2.2
#> [1,] 4.283224 4.568657
#> [2,] 4.131445 4.554851
#> [3,] 4.549746 4.501866
#> [4,] 4.290487 4.461567
#> [5,] 4.535221 4.465672
#> [6,] 4.513435 4.312687
#> [7,] 4.107480 4.179104
#> [8,] 4.872912 4.897015
#> [9,] 4.985476 4.627239
#> [10,] 4.482208 4.420522
#> [11,] 4.464052 4.353358
#> [12,] 4.268700 4.563060
#> [13,] 4.413943 4.282090
#> [14,] 4.347131 4.395149
#> [15,] 4.135076 4.436194
#> [16,] 4.614379 4.425000
#> TTCTCCTAGTGTTAGA-500.2.2 TTCTCCTGTAAGGATT-500.2.2
#> [1,] 4.382114 4.474849
#> [2,] 4.289634 4.116700
#> [3,] 4.469512 4.279678
#> [4,] 4.135671 4.191818
#> [5,] 4.588415 4.131455
#> [6,] 4.472053 4.228035
#> [7,] 4.298780 3.940979
#> [8,] 4.456301 4.835681
#> [9,] 4.732724 4.729712
#> [10,] 4.317581 4.301811
#> [11,] 4.716463 4.186452
#> [12,] 4.504065 4.351442
#> [13,] 4.168699 4.196512
#> [14,] 4.502033 4.492287
#> [15,] 4.118394 4.148893
#> [16,] 4.440041 4.330651
#> TTCTTAGCAGGTTTCA-500.2.2 TTGAACGCAAAGCGGT-500.2.2
#> [1,] 4.446108 4.852336
#> [2,] 4.305389 4.026168
#> [3,] 4.383234 4.119626
#> [4,] 4.629741 4.023364
#> [5,] 4.505988 4.604673
#> [6,] 4.509980 3.931776
#> [7,] 4.526946 4.119626
#> [8,] 4.909182 4.495327
#> [9,] 4.480040 4.520561
#> [10,] 4.457086 3.853271
#> [11,] 4.342315 3.931776
#> [12,] 4.493014 4.209346
#> [13,] 4.275449 4.642991
#> [14,] 4.487026 4.224299
#> [15,] 4.470060 4.202804
#> [16,] 4.177645 4.263551
#> TTGCGTCAGATCCCGC-500.2.2 TTGGAACAGCCAGTAG-500.2.2
#> [1,] 4.269195 4.599366
#> [2,] 4.323774 4.427061
#> [3,] 4.230342 4.672304
#> [4,] 4.241443 4.609937
#> [5,] 4.489362 4.500000
#> [6,] 4.470860 4.269556
#> [7,] 4.271970 4.056025
#> [8,] 4.872340 4.599366
#> [9,] 4.902868 4.779070
#> [10,] 4.174838 4.193446
#> [11,] 4.596670 4.361522
#> [12,] 4.574468 4.655391
#> [13,] 4.365402 4.336152
#> [14,] 4.096207 4.482030
#> [15,] 4.286772 4.349894
#> [16,] 4.342276 4.628964
#> TTGTAGGCACACGCTG-500.2.2 TTTACTGGTCTTGTCC-500.2.2
#> [1,] 4.276580 4.244987
#> [2,] 4.358477 4.252398
#> [3,] 4.226293 4.199215
#> [4,] 4.701868 4.480384
#> [5,] 4.257902 4.378378
#> [6,] 4.161638 4.444202
#> [7,] 4.357759 4.180907
#> [8,] 4.908046 4.908893
#> [9,] 4.537356 4.948561
#> [10,] 4.309626 4.459459
#> [11,] 4.123563 4.213165
#> [12,] 4.926006 4.233217
#> [13,] 4.447557 4.369660
#> [14,] 4.754310 4.284220
#> [15,] 4.357040 4.451613
#> [16,] 4.598420 4.414996
#> TTTATGCGTACCATCA-500.2.2 TTTCCTCTCTCTTGAT-500.2.2
#> [1,] 4.389716 4.284000
#> [2,] 4.349120 4.028000
#> [3,] 4.537212 4.668000
#> [4,] 4.637348 4.053333
#> [5,] 4.361299 4.330667
#> [6,] 4.132612 4.840000
#> [7,] 3.702300 4.489333
#> [8,] 4.765900 4.962667
#> [9,] 4.656292 4.653333
#> [10,] 4.267930 4.385333
#> [11,] 4.179973 4.328000
#> [12,] 4.362652 4.500000
#> [13,] 4.362652 4.517333
#> [14,] 4.591340 4.720000
#> [15,] 4.290934 4.557333
#> [16,] 4.250338 4.562667
#> TTTGGTTAGTGCGTGA-500.2.2 TTTGGTTTCAGGTTCA-500.2.2 AAACCTGAGATCCGAG-r17
#> [1,] 4.480188 4.586563 4.519960
#> [2,] 4.319082 4.375969 4.008483
#> [3,] 4.333160 4.516796 4.069860
#> [4,] 4.423879 4.494832 4.061377
#> [5,] 4.682482 4.400517 5.393214
#> [6,] 4.226277 4.462532 4.117764
#> [7,] 4.191867 3.921189 4.717565
#> [8,] 4.855057 4.980620 4.418663
#> [9,] 4.820647 4.753230 4.062375
#> [10,] 4.529197 4.248062 4.097804
#> [11,] 4.333160 4.534884 4.119760
#> [12,] 4.451512 4.357881 3.977046
#> [13,] 4.520334 4.244186 4.207585
#> [14,] 4.345151 4.236434 4.389721
#> [15,] 4.200209 3.989664 4.015968
#> [16,] 4.453076 4.457364 4.058882
#> AAACGGGCATTATCTC-r17 AAAGCAACAAGTCTAC-r17 AAAGTAGCAGGGTACA-r17
#> [1,] 4.370283 4.186924 4.359860
#> [2,] 4.495283 4.264273 4.355764
#> [3,] 4.229953 4.072744 4.032768
#> [4,] 4.055425 3.977901 4.141603
#> [5,] 4.561321 4.681400 4.906378
#> [6,] 4.347877 4.316759 3.863663
#> [7,] 4.324292 4.504604 4.002926
#> [8,] 4.363208 5.011050 4.967817
#> [9,] 4.010613 4.452118 3.865418
#> [10,] 4.801887 4.274401 4.259801
#> [11,] 4.260613 4.425414 4.225863
#> [12,] 4.353774 4.300184 3.862493
#> [13,] 4.633255 4.555249 4.526039
#> [14,] 4.228774 4.042357 4.189585
#> [15,] 3.932783 4.242173 4.092452
#> [16,] 4.524764 4.522099 4.226448
#> AAAGTAGCATGATCCA-r17 AAATGCCCATCAGTCA-r17 AAATGCCGTAGCGTCC-r17
#> [1,] 4.019231 4.351248 3.967227
#> [2,] 4.611264 4.283109 4.410924
#> [3,] 4.247253 4.022073 4.454622
#> [4,] 4.464286 4.014395 4.303361
#> [5,] 4.923077 4.606526 4.465546
#> [6,] 3.935440 4.386756 3.951261
#> [7,] 4.682692 4.569098 4.536134
#> [8,] 4.858516 4.835893 4.863025
#> [9,] 4.127747 4.366603 4.618487
#> [10,] 4.038462 4.445298 4.031933
#> [11,] 4.620879 4.467370 4.442857
#> [12,] 4.420330 4.102687 4.406723
#> [13,] 4.086538 4.390595 4.063866
#> [14,] 4.353022 4.387716 4.384874
#> [15,] 3.934066 4.002879 4.137815
#> [16,] 4.083791 4.575816 4.439496
#> AAATGCCGTGCAGACA-r17 AAATGCCTCCTTTCTC-r17 AAATGCCTCTCTGAGA-r17
#> [1,] 4.357977 4.015952 4.267304
#> [2,] 4.263619 4.271186 3.958876
#> [3,] 4.562257 4.387836 4.170866
#> [4,] 4.354086 3.968096 4.185925
#> [5,] 4.556420 4.806580 5.209094
#> [6,] 4.211089 4.378863 4.089487
#> [7,] 4.346304 4.225324 4.955691
#> [8,] 4.574903 4.683948 4.283811
#> [9,] 4.207198 4.467597 4.017955
#> [10,] 4.157588 4.261216 4.045468
#> [11,] 4.569066 4.249252 4.212858
#> [12,] 4.263619 4.316052 4.226180
#> [13,] 4.199416 4.233300 4.010426
#> [14,] 4.076848 4.132602 4.344917
#> [15,] 4.037938 4.194417 4.121923
#> [16,] 4.303502 4.683948 4.119606
#> AACACGTGTCTTGATG-r17 AACCATGCAATGAATG-r17 AACCATGTCATTGCCC-r17
#> [1,] 4.392000 4.413529 4.131162
#> [2,] 4.368667 4.338235 4.149648
#> [3,] 4.122667 4.280000 4.135563
#> [4,] 4.004667 4.009412 4.191021
#> [5,] 5.656000 4.457059 4.685739
#> [6,] 4.240000 4.261765 4.065141
#> [7,] 4.663333 4.374118 4.385563
#> [8,] 4.888667 4.518824 4.604754
#> [9,] 4.244667 4.352941 4.629401
#> [10,] 4.276000 4.314118 4.191901
#> [11,] 4.126000 3.992941 4.168134
#> [12,] 4.498667 4.538824 4.370599
#> [13,] 4.198000 4.344706 4.355634
#> [14,] 3.605333 4.144706 4.022887
#> [15,] 4.166667 4.564706 3.933979
#> [16,] 4.676000 4.474118 4.492958
#> AACCGCGAGCTGTTCA-r17 AACCGCGGTGGTGTAG-r17 AACCGCGTCCAAAGTC-r17
#> [1,] 4.163732 4.248053 4.504762
#> [2,] 4.285211 4.108108 4.057823
#> [3,] 3.999120 4.129409 4.211565
#> [4,] 4.034331 4.512826 4.182993
#> [5,] 4.694542 5.005726 5.322449
#> [6,] 4.375880 4.168804 4.125170
#> [7,] 4.457746 4.784013 4.680952
#> [8,] 4.773768 4.359597 4.508844
#> [9,] 4.360915 4.254924 4.451020
#> [10,] 4.296655 4.281493 4.397279
#> [11,] 4.147007 4.250802 3.976871
#> [12,] 4.374120 4.075813 3.929932
#> [13,] 4.562500 4.109482 4.192517
#> [14,] 4.274648 4.604672 3.998639
#> [15,] 4.120599 3.884333 4.093197
#> [16,] 4.492958 4.251260 4.319728
#> AACTCAGAGTCGTACT-r17 AACTCAGAGTGTACCT-r17 AACTCAGGTTGGTAAA-r17
#> [1,] 4.341444 4.602996 4.384485
#> [2,] 4.114878 4.006242 3.810872
#> [3,] 4.266853 3.915106 4.286523
#> [4,] 4.380136 4.332085 4.214043
#> [5,] 5.558835 5.248439 5.096263
#> [6,] 4.406462 3.806492 3.986410
#> [7,] 4.913442 4.833958 4.724802
#> [8,] 4.720383 4.387016 4.214609
#> [9,] 4.333865 3.957553 4.041903
#> [10,] 3.885122 3.747815 4.216874
#> [11,] 4.280814 4.222222 4.288222
#> [12,] 4.044675 3.825218 4.283126
#> [13,] 3.822098 4.203496 4.334655
#> [14,] 4.369765 4.217228 4.271801
#> [15,] 3.844037 3.960050 4.015289
#> [16,] 4.373753 4.460674 4.105323
#> AACTCTTAGCCCAATT-r17 AACTTTCCAAGCTGGA-r17 AACTTTCTCAAACCAC-r17
#> [1,] 4.231873 4.298646 4.116564
#> [2,] 4.131873 4.396785 4.602590
#> [3,] 4.330677 4.033841 4.432856
#> [4,] 4.500398 4.422166 4.347648
#> [5,] 4.949004 4.573604 4.551466
#> [6,] 4.039841 4.395093 3.935924
#> [7,] 4.875299 4.626904 4.662577
#> [8,] 4.314741 4.796108 4.887526
#> [9,] 4.125100 4.649746 4.374915
#> [10,] 4.192829 4.661591 4.438991
#> [11,] 4.501594 4.518613 4.436264
#> [12,] 4.194422 4.635364 3.963190
#> [13,] 4.139841 4.314721 4.089980
#> [14,] 4.293227 4.065990 4.443081
#> [15,] 4.000797 4.489002 3.907294
#> [16,] 4.204382 4.161591 4.232447
#> AACTTTCTCAGCAACT-r17 AACTTTCTCCTATGTT-r17 AAGACCTCATGGAATA-r17
#> [1,] 3.941244 4.511656 4.341329
#> [2,] 4.016129 4.299387 4.138431
#> [3,] 4.148618 4.269939 4.215392
#> [4,] 4.379032 4.131288 4.065967
#> [5,] 4.834101 4.622086 5.050975
#> [6,] 4.103687 4.457669 4.346327
#> [7,] 4.688940 4.533742 4.582709
#> [8,] 4.683180 4.458896 4.758621
#> [9,] 3.986175 4.548466 4.300350
#> [10,] 4.056452 4.272393 4.289855
#> [11,] 4.359447 4.634356 4.388806
#> [12,] 4.228111 4.387730 4.328336
#> [13,] 4.324885 4.343558 4.078961
#> [14,] 4.347926 4.417178 3.985007
#> [15,] 3.841014 4.262577 4.066467
#> [16,] 4.168203 4.280982 4.506747
#> AAGCCGCAGGTGCAAC-r17 AAGCCGCGTCCCTTGT-r17 AAGTCTGCAGATAATG-r17
#> [1,] 4.126184 4.119813 4.411336
#> [2,] 4.255043 3.903949 4.160324
#> [3,] 4.247839 4.147590 4.178138
#> [4,] 4.038699 4.324297 4.256680
#> [5,] 5.117538 5.242303 4.951417
#> [6,] 4.307946 4.170683 3.983806
#> [7,] 4.899547 5.087684 4.755466
#> [8,] 4.473240 4.249331 4.312551
#> [9,] 4.258748 3.927376 4.240486
#> [10,] 4.236929 4.053548 4.263968
#> [11,] 4.233224 4.158300 4.165182
#> [12,] 4.063812 4.124833 4.084211
#> [13,] 4.137505 4.176372 4.280972
#> [14,] 4.473034 4.376841 4.279352
#> [15,] 4.056814 3.749331 4.224291
#> [16,] 4.165912 3.941432 4.319838
#> AATCCAGCAACACGCC-r17 AATCGGTAGATGTAAC-r17 AATCGGTCACAAGTAA-r17
#> [1,] 4.348951 4.466667 4.498285
#> [2,] 4.040996 3.927957 4.348199
#> [3,] 4.252806 4.168817 4.306175
#> [4,] 4.293802 4.317204 4.455403
#> [5,] 4.866764 4.837634 4.635506
#> [6,] 4.077599 4.239785 4.107204
#> [7,] 4.783797 4.919355 4.596913
#> [8,] 4.587116 4.468817 4.754717
#> [9,] 4.271352 3.936559 4.467410
#> [10,] 4.070278 3.990323 4.429674
#> [11,] 4.313324 4.081720 4.191252
#> [12,] 4.095168 4.051613 4.428816
#> [13,] 4.058077 4.050538 4.399657
#> [14,] 4.449976 4.250538 3.952830
#> [15,] 3.926794 3.756989 4.256432
#> [16,] 3.937042 3.776344 4.588336
#> ACACCCTGTCCAGTGC-r17 ACACCCTTCTAACTGG-r17 ACACTGAGTTCGGGCT-r17
#> [1,] 4.272815 4.159515 4.616311
#> [2,] 4.053021 4.374067 4.101514
#> [3,] 4.110219 4.409515 4.337233
#> [4,] 4.129820 4.469216 4.368204
#> [5,] 5.169023 4.565299 4.751893
#> [6,] 4.013817 4.362873 3.981418
#> [7,] 4.664846 4.090485 4.619408
#> [8,] 4.252892 4.955224 4.560564
#> [9,] 4.197622 4.819030 4.165864
#> [10,] 4.080334 4.413246 4.001721
#> [11,] 4.107005 4.390858 4.340330
#> [12,] 4.099614 4.278918 4.359601
#> [13,] 4.166774 4.478545 4.378527
#> [14,] 4.491645 4.244403 4.223675
#> [15,] 4.035347 3.983209 4.015485
#> [16,] 4.046594 4.308769 4.184790
#> ACAGCCGAGAGTGAGA-r17 ACAGCTAAGCGATTCT-r17 ACAGCTAGTCTCCACT-r17
#> [1,] 4.327713 4.514851 4.229523
#> [2,] 4.527859 4.603960 4.183854
#> [3,] 4.267595 4.251125 4.281968
#> [4,] 4.225806 4.365437 4.326753
#> [5,] 4.043255 4.441044 4.947260
#> [6,] 4.361437 4.451845 4.057160
#> [7,] 4.371701 4.086409 4.736005
#> [8,] 5.000000 4.981098 4.489098
#> [9,] 4.818182 4.394239 4.261344
#> [10,] 4.812317 4.736274 4.189157
#> [11,] 4.152493 4.495950 4.362404
#> [12,] 4.409824 4.452745 4.020035
#> [13,] 4.466276 4.662466 4.098409
#> [14,] 4.427419 4.119712 4.560401
#> [15,] 4.737537 4.180918 3.890984
#> [16,] 4.349707 4.282628 4.011196
#> ACAGCTATCATCGATG-r17 ACATACGGTAAAGTCA-r17 ACCAGTAGTAGCCTAT-r17
#> [1,] 4.487836 4.150142 4.440077
#> [2,] 4.018566 4.027384 4.787152
#> [3,] 4.475032 3.915014 4.360499
#> [4,] 4.359155 4.161473 4.298178
#> [5,] 4.918054 4.515581 4.501438
#> [6,] 4.332266 4.748820 3.904123
#> [7,] 4.638924 4.478754 4.111218
#> [8,] 4.448784 4.480642 4.739214
#> [9,] 4.209987 4.220963 4.310642
#> [10,] 4.114597 4.336166 4.424736
#> [11,] 4.350192 4.186969 4.279003
#> [12,] 4.583867 4.633617 4.400767
#> [13,] 4.197183 4.507082 4.647172
#> [14,] 4.238156 4.773371 4.616491
#> [15,] 4.074264 4.338055 3.966443
#> [16,] 4.132522 4.907460 4.472675
#> ACCCACTGTGAAAGAG-r17 ACGAGCCGTCAAACTC-r17 ACGATACAGACTACAA-r17
#> [1,] 4.076675 4.259420 4.216683
#> [2,] 4.338176 4.789130 4.194631
#> [3,] 4.038741 4.028261 4.316395
#> [4,] 4.426150 4.141304 4.475551
#> [5,] 4.157385 4.909420 4.483221
#> [6,] 3.974980 4.154348 4.144775
#> [7,] 4.557708 4.310870 4.214765
#> [8,] 4.707022 5.121739 4.551294
#> [9,] 4.089588 4.337681 4.402685
#> [10,] 4.504439 4.339130 4.272291
#> [11,] 4.417272 4.491304 4.502397
#> [12,] 4.363196 3.954348 4.254075
#> [13,] 4.142857 4.042754 4.211889
#> [14,] 4.020178 4.765217 4.488015
#> [15,] 4.456013 4.028986 4.439118
#> [16,] 4.167070 4.410145 4.337488
#> ACGATACTCCAAAGTC-r17 ACGATGTGTTCCCGAG-r17 ACGCAGCAGTTAAGTG-r17
#> [1,] 4.306296 4.250696 4.383112
#> [2,] 4.002269 4.581244 4.258796
#> [3,] 4.113443 4.350975 4.312744
#> [4,] 4.056438 4.373259 4.304144
#> [5,] 5.273398 4.685237 4.549648
#> [6,] 3.898752 4.249768 4.247068
#> [7,] 4.805445 4.747447 4.390930
#> [8,] 4.437890 4.877437 4.776388
#> [9,] 3.925695 4.308264 4.515246
#> [10,] 4.132728 4.367688 4.294762
#> [11,] 4.078276 4.323120 4.230649
#> [12,] 4.377482 4.574745 4.272869
#> [13,] 4.171015 4.245125 4.379203
#> [14,] 4.137833 4.256267 4.011728
#> [15,] 4.432218 4.759517 4.163409
#> [16,] 4.470505 4.226555 4.515246
#> ACGCCAGAGTTGAGAT-r17 ACGCCGACATACAGCT-r17 ACGGAGAAGTGTGAAT-r17
#> [1,] 4.278646 4.259475 4.244592
#> [2,] 4.228766 3.917307 4.287022
#> [3,] 4.260016 4.319640 3.935940
#> [4,] 4.338542 4.020408 3.935940
#> [5,] 4.879407 4.895309 4.957571
#> [6,] 4.185296 3.950437 4.016639
#> [7,] 4.750000 4.749801 4.776206
#> [8,] 4.668470 4.388815 4.649750
#> [9,] 4.253005 4.040286 4.098170
#> [10,] 4.065304 4.208057 3.946755
#> [11,] 4.338942 4.407103 4.381864
#> [12,] 4.048878 4.302677 4.147255
#> [13,] 3.953125 4.336337 4.108985
#> [14,] 4.409455 4.119534 4.836106
#> [15,] 3.939303 4.207792 3.915141
#> [16,] 3.971955 4.151338 3.988353
#> ACGGGCTTCTTGAGGT-r17 ACTATCTGTCTTGTCC-r17 ACTGAACTCGTCACGG-r17
#> [1,] 4.323229 4.130775 4.379827
#> [2,] 4.244664 3.927565 3.913221
#> [3,] 4.094649 4.195771 4.301681
#> [4,] 4.116301 4.480814 4.218537
#> [5,] 4.883390 5.024667 4.911404
#> [6,] 4.063099 3.974158 4.060427
#> [7,] 4.233220 4.821848 4.715129
#> [8,] 4.768327 4.541504 4.429350
#> [9,] 4.577482 4.300313 4.405725
#> [10,] 4.391277 4.097886 4.038164
#> [11,] 4.178781 4.371966 4.326670
#> [12,] 4.255800 4.129209 4.206270
#> [13,] 4.493659 4.065388 4.208542
#> [14,] 4.500155 4.456930 4.473876
#> [15,] 3.951748 4.039937 3.990005
#> [16,] 4.193628 4.158183 4.070423
#> ACTGAGTCAAACAACA-r17 ACTGAGTTCTTACCGC-r17 ACTGATGAGGCTAGAC-r17
#> [1,] 4.127557 4.421761 4.239343
#> [2,] 4.400722 3.863173 3.985105
#> [3,] 4.320096 4.199418 3.963534
#> [4,] 4.371841 4.221616 4.164355
#> [5,] 4.980746 5.394105 5.137134
#> [6,] 4.723225 3.909753 3.765280
#> [7,] 4.155235 4.811863 4.761685
#> [8,] 4.434416 4.045124 4.703647
#> [9,] 4.344164 3.926128 4.167951
#> [10,] 4.432010 3.969068 3.775552
#> [11,] 4.570397 4.310771 4.179764
#> [12,] 4.563177 4.133552 3.649718
#> [13,] 3.998797 4.219068 3.949153
#> [14,] 4.424789 4.281295 4.666667
#> [15,] 4.635379 3.807496 3.698511
#> [16,] 4.713598 3.969068 4.014895
#> ACTGTCCAGTATCGAA-r17 ACTGTCCCAGCTGGCT-r17 ACTGTCCTCAAGGCTT-r17
#> [1,] 4.232068 4.346469 4.447790
#> [2,] 4.219409 4.219209 3.951954
#> [3,] 4.144866 4.308051 3.945548
#> [4,] 4.218003 4.293079 3.951954
#> [5,] 4.704641 4.876977 5.379244
#> [6,] 4.046414 4.218927 3.905189
#> [7,] 4.807314 4.593644 5.073030
#> [8,] 4.583685 4.541667 4.401025
#> [9,] 4.118143 4.282486 3.962844
#> [10,] 4.361463 4.303249 3.884049
#> [11,] 4.102672 4.453672 4.259449
#> [12,] 3.912799 4.419774 4.057015
#> [13,] 4.271449 4.350141 4.276746
#> [14,] 4.343179 4.208051 4.420884
#> [15,] 3.967651 4.101130 4.064061
#> [16,] 4.222222 4.419068 4.215887
#> ACTTTCAAGGACGAAA-r17 AGAATAGAGTGGGTTG-r17 AGATCTGAGGGTGTGT-r17
#> [1,] 4.116825 4.207154 4.156863
#> [2,] 4.104127 3.983607 4.654412
#> [3,] 4.138730 4.159463 4.119281
#> [4,] 4.265079 4.376304 4.179739
#> [5,] 5.153333 5.019374 4.349673
#> [6,] 4.017143 3.882265 4.075980
#> [7,] 4.790794 4.784650 4.161765
#> [8,] 4.457143 4.432191 4.625000
#> [9,] 4.096190 3.936662 5.093137
#> [10,] 3.968254 4.157973 5.066176
#> [11,] 4.222222 4.330104 4.513072
#> [12,] 4.011746 3.818927 4.133170
#> [13,] 4.148889 4.279434 4.368464
#> [14,] 4.477143 4.544709 4.415850
#> [15,] 3.877143 4.124441 4.924837
#> [16,] 4.065714 4.128167 4.256536
#> AGATCTGAGTGTTAGA-r17 AGATCTGGTCAACTGT-r17 AGATCTGGTCGCGTGT-r17
#> [1,] 4.272832 3.892308 4.260681
#> [2,] 4.087861 4.182418 4.181028
#> [3,] 3.850867 4.228571 3.875453
#> [4,] 4.264740 4.191209 4.083273
#> [5,] 5.027746 4.741758 5.089066
#> [6,] 4.179191 4.064835 3.810282
#> [7,] 5.346821 4.156044 4.795800
#> [8,] 4.443931 4.752747 4.566980
#> [9,] 4.075145 3.943956 4.172339
#> [10,] 4.317919 4.208791 3.784214
#> [11,] 4.139884 4.373626 4.367125
#> [12,] 4.073988 4.073626 4.079652
#> [13,] 4.435838 4.393407 4.055757
#> [14,] 4.324855 4.293407 4.624185
#> [15,] 3.997688 4.124176 3.869660
#> [16,] 4.091329 4.672527 4.097755
#> AGATTGCTCCATGAAC-r17 AGCAGCCGTAAACACA-r17 AGCATACGTAGGGACT-r17
#> [1,] 4.431492 4.354659 4.433643
#> [2,] 3.690459 4.333797 4.159763
#> [3,] 3.889527 4.511127 4.156805
#> [4,] 3.949426 4.015994 4.461961
#> [5,] 5.293400 4.482615 4.830938
#> [6,] 3.858680 4.273296 4.006340
#> [7,] 4.921449 4.254520 4.695266
#> [8,] 4.315280 4.536857 4.449281
#> [9,] 4.296628 4.150904 4.072697
#> [10,] 4.027260 4.258693 4.104396
#> [11,] 3.995696 4.419332 4.105241
#> [12,] 3.913917 4.175939 4.165680
#> [13,] 4.189024 4.283727 3.962806
#> [14,] 4.625538 4.207928 4.312342
#> [15,] 3.963056 4.178720 4.114962
#> [16,] 4.131277 4.696801 4.173288
#> AGCATACGTATCTGCA-r17 AGCCTAAAGCGATGAC-r17 AGCGGTCGTGTCGCTG-r17
#> [1,] 4.340209 4.406623 4.468354
#> [2,] 3.877888 4.113907 4.218003
#> [3,] 4.168592 4.145695 4.326301
#> [4,] 4.274202 4.226821 4.061885
#> [5,] 5.035479 4.504636 4.611814
#> [6,] 4.142739 4.108609 4.309423
#> [7,] 4.863036 4.364238 4.108298
#> [8,] 4.344609 4.797682 4.493671
#> [9,] 4.227173 4.201656 4.293952
#> [10,] 4.080308 4.247351 4.343179
#> [11,] 4.113586 4.319868 4.160338
#> [12,] 3.986249 4.288411 4.326301
#> [13,] 4.231848 4.251987 4.368495
#> [14,] 4.524477 4.280464 4.420534
#> [15,] 3.800330 4.121523 4.308017
#> [16,] 3.896040 4.322185 4.305204
#> AGCGTATCAATTGCTG-r17 AGCTTGAAGTCCTCCT-r17 AGCTTGAGTCCATGAT-r17
#> [1,] 4.687750 4.271576 4.152952
#> [2,] 3.657326 4.536025 4.079606
#> [3,] 4.457166 4.263658 4.329383
#> [4,] 4.470777 4.346002 4.240832
#> [5,] 4.771017 4.651623 5.057692
#> [6,] 4.002402 4.215360 4.135510
#> [7,] 4.391513 4.371338 4.754696
#> [8,] 4.278623 4.752969 4.459750
#> [9,] 4.084868 4.660333 4.158318
#> [10,] 3.780624 4.266033 4.214669
#> [11,] 4.079263 4.274743 4.286673
#> [12,] 4.280224 4.445764 4.091458
#> [13,] 4.235388 4.477435 4.258721
#> [14,] 4.423539 4.241489 4.572451
#> [15,] 4.211369 4.247823 4.069097
#> [16,] 4.196157 4.536817 4.190742
#> AGGCCACCACAGCGTC-r17 AGGCCACGTACCAGTT-r17 AGGCCACTCGGAAATA-r17
#> [1,] 4.365725 4.177655 4.373212
#> [2,] 4.131163 4.351787 4.053966
#> [3,] 3.944950 4.262708 4.041612
#> [4,] 4.307803 4.613488 4.308192
#> [5,] 4.890857 4.510317 4.695059
#> [6,] 3.892772 4.195269 4.070871
#> [7,] 4.651029 4.285355 4.473342
#> [8,] 4.602202 4.664318 4.725618
#> [9,] 4.583533 4.255159 4.180754
#> [10,] 4.052178 4.223956 3.938231
#> [11,] 4.156056 4.424761 4.389467
#> [12,] 4.065582 4.266734 4.041612
#> [13,] 4.323121 4.176145 3.974642
#> [14,] 4.347535 4.429794 4.096879
#> [15,] 3.975108 4.206844 4.066970
#> [16,] 4.146003 4.374434 4.592328
#> AGGGAGTGTACATGTC-r17 AGGTCATAGATGTAAC-r17 AGTAGTCGTAAACCTC-r17
#> [1,] 4.537003 4.218530 4.161880
#> [2,] 3.888685 4.299094 4.342037
#> [3,] 4.300306 4.485398 4.356832
#> [4,] 4.060550 3.947633 4.127937
#> [5,] 4.319266 4.587110 4.682332
#> [6,] 4.099083 4.540785 3.763272
#> [7,] 4.464832 4.345418 4.621410
#> [8,] 4.316820 4.715005 4.785901
#> [9,] 4.374312 4.344411 4.354221
#> [10,] 4.305810 4.178248 4.221062
#> [11,] 4.522324 4.369587 4.017406
#> [12,] 4.342508 4.281974 4.285466
#> [13,] 4.221407 4.168177 4.068755
#> [14,] 4.008563 3.994965 4.423847
#> [15,] 3.974312 4.053374 4.053090
#> [16,] 4.210398 4.481370 4.480418
#> AGTCTTTAGTACATGA-r17 AGTGGGAAGCCAGAAC-r17 AGTGTCATCTTACCTA-r17
#> [1,] 4.156917 4.352841 4.358581
#> [2,] 4.476323 4.052841 3.965484
#> [3,] 4.252553 4.360227 4.273250
#> [4,] 4.333333 3.928977 4.013423
#> [5,] 4.864438 4.993750 5.181208
#> [6,] 3.998143 3.904545 4.089166
#> [7,] 4.541318 4.697727 4.418025
#> [8,] 4.969359 4.631818 4.858102
#> [9,] 4.476323 4.050568 4.218600
#> [10,] 4.160631 4.023295 4.181208
#> [11,] 4.400186 4.286932 4.159156
#> [12,] 4.318477 4.318182 3.934803
#> [13,] 4.056639 4.134659 4.348035
#> [14,] 4.149489 4.149432 4.292426
#> [15,] 3.980501 4.183523 4.255034
#> [16,] 4.398329 4.409091 4.589645
#> ATAACGCGTTCCACTC-r17 ATAACGCGTTGTGGCC-r17 ATAAGAGAGTGAATTG-r17
#> [1,] 4.410088 4.173684 4.106493
#> [2,] 3.949960 4.118129 4.222332
#> [3,] 4.179426 4.281287 4.008854
#> [4,] 4.201754 4.237427 4.062223
#> [5,] 4.953748 4.664327 5.233153
#> [6,] 3.960526 4.190643 4.017954
#> [7,] 4.690789 4.357895 4.978849
#> [8,] 4.570574 4.628655 4.657895
#> [9,] 4.320973 4.213450 4.036153
#> [10,] 3.932217 4.255556 4.093704
#> [11,] 4.235646 4.254386 4.199951
#> [12,] 4.088716 4.079532 3.956714
#> [13,] 4.011364 4.214620 4.061485
#> [14,] 4.482057 4.549708 4.573783
#> [15,] 3.918062 4.335088 4.000492
#> [16,] 4.088517 4.285380 3.993851
#> ATAAGAGCACATGACT-r17 ATAGACCGTTGTCGCG-r17 ATAGACCTCGTCACGG-r17
#> [1,] 4.184801 4.681215 4.700252
#> [2,] 4.248129 3.656354 3.892191
#> [3,] 4.004606 3.902762 4.135013
#> [4,] 4.168106 4.477901 4.481612
#> [5,] 5.023028 5.085083 4.869521
#> [6,] 4.001727 3.944751 4.032242
#> [7,] 4.805412 4.770718 4.522922
#> [8,] 4.670697 4.147514 4.499748
#> [9,] 4.182499 4.245304 4.201511
#> [10,] 4.099597 3.945304 4.100756
#> [11,] 4.108808 4.172376 4.200000
#> [12,] 4.146805 4.127624 4.024685
#> [13,] 4.015544 4.188950 4.144584
#> [14,] 4.411054 4.373481 4.235768
#> [15,] 3.858952 3.850276 3.999496
#> [16,] 4.234312 3.908287 3.906297
#> ATCACGAGTGAGTGAC-r17 ATCACGATCAACACTG-r17 ATCATCTGTTACAGAA-r17
#> [1,] 4.411215 4.474649 4.242252
#> [2,] 4.181854 3.913256 4.395319
#> [3,] 4.167056 3.848503 4.387097
#> [4,] 4.282710 4.076359 4.242252
#> [5,] 5.040498 4.956017 4.644529
#> [6,] 4.191589 3.791692 4.514231
#> [7,] 4.844626 4.715944 4.430740
#> [8,] 4.413941 4.551008 4.719165
#> [9,] 4.251947 4.263286 4.533839
#> [10,] 4.091121 3.789859 4.641999
#> [11,] 3.947040 4.145388 4.106894
#> [12,] 4.192757 3.955406 4.686275
#> [13,] 4.133956 4.065974 4.326376
#> [14,] 4.693536 4.719609 4.254269
#> [15,] 4.006620 3.761148 4.316256
#> [16,] 3.995327 3.748931 4.423150
#> ATCCACCTCACGCATA-r17 ATCCGAAAGCTAAACA-r17 ATCTACTCAACTGCTA-r17
#> [1,] 4.314970 4.434199 4.383659
#> [2,] 4.088623 3.869540 4.465364
#> [3,] 4.134132 4.041393 4.344583
#> [4,] 4.154491 4.139595 4.335702
#> [5,] 5.050898 5.169569 4.555950
#> [6,] 4.120958 3.901228 4.188277
#> [7,] 4.588024 4.896375 4.253108
#> [8,] 4.341916 4.163289 4.555062
#> [9,] 4.350299 3.950328 4.563943
#> [10,] 4.196407 4.050814 4.539964
#> [11,] 4.441916 4.258065 4.245115
#> [12,] 4.301796 4.156437 4.687389
#> [13,] 4.323353 4.124465 4.609236
#> [14,] 4.107784 4.282900 4.353464
#> [15,] 4.053892 3.892378 4.301954
#> [16,] 4.149701 3.929774 4.433393
#> ATCTACTCAGTCACTA-r17 ATCTGCCAGCGCCTTG-r17 ATCTGCCAGTAAGTAC-r17
#> [1,] 4.273816 4.253591 4.379365
#> [2,] 4.104284 4.278453 3.953571
#> [3,] 4.251550 4.319890 4.026190
#> [4,] 4.402621 4.364088 4.122222
#> [5,] 4.834273 4.560773 4.832937
#> [6,] 4.151353 4.333702 3.918254
#> [7,] 4.708568 4.361326 4.657143
#> [8,] 4.446308 4.778453 4.515476
#> [9,] 4.090051 4.421547 4.166270
#> [10,] 4.100620 4.424309 3.944048
#> [11,] 4.359076 4.312707 4.312302
#> [12,] 4.254510 4.255801 4.060714
#> [13,] 4.214346 4.311050 4.225794
#> [14,] 4.248450 4.164088 4.374603
#> [15,] 4.004510 4.380663 3.967857
#> [16,] 4.141488 4.354696 4.255952
#> ATCTGCCGTATCACCA-r17 ATGAGGGCAGGACCCT-r17 ATGGGAGAGATAGTCA-r17
#> [1,] 4.784731 4.413775 4.594710
#> [2,] 3.744681 4.056541 4.877986
#> [3,] 4.102628 4.027756 3.980375
#> [4,] 4.359825 4.241326 4.285836
#> [5,] 5.259700 5.228990 4.456485
#> [6,] 3.961202 4.202519 4.690273
#> [7,] 4.626408 5.064765 4.314846
#> [8,] 4.410513 4.405808 4.726962
#> [9,] 4.159574 4.221280 3.885666
#> [10,] 3.768461 4.163197 4.723549
#> [11,] 4.143304 4.204575 4.332765
#> [12,] 4.098874 4.270111 4.420648
#> [13,] 4.073217 4.225906 4.808020
#> [14,] 4.041302 4.370856 4.415529
#> [15,] 4.077597 3.995888 3.781570
#> [16,] 4.141427 4.126960 4.098123
#> ATGGGAGCAATCTGCA-r17 ATGGGAGCAGATGAGC-r17 ATTACTCAGGGCATGT-r17
#> [1,] 4.333055 4.285267 4.223232
#> [2,] 4.225376 4.206420 4.189394
#> [3,] 4.082638 4.185021 4.441414
#> [4,] 3.743740 4.454815 4.127273
#> [5,] 5.238731 4.857449 4.905051
#> [6,] 4.224541 4.049053 4.137879
#> [7,] 4.636060 4.668313 4.868182
#> [8,] 4.644407 4.663539 4.298485
#> [9,] 4.454925 4.259753 4.213636
#> [10,] 4.690317 4.033416 4.076768
#> [11,] 4.049249 4.271605 4.462626
#> [12,] 4.858932 4.184198 4.223232
#> [13,] 3.987479 4.120988 4.379798
#> [14,] 4.314691 4.498765 4.482828
#> [15,] 4.426544 3.853333 4.102020
#> [16,] 4.631052 4.183539 4.221717
#> ATTCTACAGTCATGCT-r17 ATTCTACGTCATATCG-r17 ATTCTACGTGATGTGG-r17
#> [1,] 4.654073 4.319507 4.318939
#> [2,] 3.815230 4.243681 4.406539
#> [3,] 4.171192 4.113199 4.291795
#> [4,] 4.125148 4.365306 4.401604
#> [5,] 5.007084 4.969324 4.698334
#> [6,] 4.015348 4.191618 3.967921
#> [7,] 4.834711 4.637287 4.289328
#> [8,] 4.543093 4.639879 4.753856
#> [9,] 4.072019 4.146684 4.096237
#> [10,] 3.992916 4.158134 4.090068
#> [11,] 4.244392 4.240225 4.435534
#> [12,] 4.006494 4.095269 4.106724
#> [13,] 4.113341 4.098725 4.117829
#> [14,] 4.360094 4.378051 4.341147
#> [15,] 3.962810 4.000000 4.325725
#> [16,] 3.921488 4.292072 4.298581
#> ATTCTACGTTCCGTCT-r17 ATTGGACTCTCTAGGA-r17 ATTGGTGCACTGTGTA-r17
#> [1,] 4.149131 4.684476 4.518137
#> [2,] 4.059927 4.043077 3.883357
#> [3,] 4.054285 4.210909 4.044452
#> [4,] 4.265782 4.292308 4.406828
#> [5,] 5.060384 4.739580 4.858464
#> [6,] 4.063586 4.021538 4.197368
#> [7,] 4.847972 4.508531 4.869132
#> [8,] 4.481244 4.780979 4.578947
#> [9,] 4.139982 4.262937 4.290185
#> [10,] 4.205550 4.244196 4.193457
#> [11,] 4.423757 4.406434 4.293030
#> [12,] 4.150656 4.230769 4.078236
#> [13,] 4.171394 4.150490 4.156117
#> [14,] 4.539036 4.201678 4.229730
#> [15,] 3.848429 4.177343 4.030583
#> [16,] 4.149283 4.368392 4.226174
#> ATTTCTGCAAGTTGTC-r17 ATTTCTGGTAGGGTAC-r17 CAACTAGAGCTGGAAC-r17
#> [1,] 4.200913 4.170264 4.380202
#> [2,] 4.477495 4.381295 4.378941
#> [3,] 4.044357 4.087530 4.303909
#> [4,] 4.150685 4.249400 4.351198
#> [5,] 4.653620 4.532374 4.487390
#> [6,] 4.297456 4.326139 4.350567
#> [7,] 4.264840 4.623501 4.295082
#> [8,] 4.565558 4.623501 4.872005
#> [9,] 4.324201 4.245803 4.420555
#> [10,] 4.571429 4.312950 4.304540
#> [11,] 4.267449 4.551559 4.220050
#> [12,] 4.735160 4.169065 4.382724
#> [13,] 4.428571 4.587530 4.435687
#> [14,] 4.273320 4.468825 4.118537
#> [15,] 4.209393 4.413669 4.363178
#> [16,] 4.631442 4.442446 4.601513
#> CAACTAGTCAAACGGG-r17 CAACTAGTCAGTCAGT-r17 CAAGAAATCCAGTAGT-r17
#> [1,] 4.586106 4.124289 4.454021
#> [2,] 4.475538 3.937713 3.917526
#> [3,] 4.061644 4.190557 3.872165
#> [4,] 4.087084 4.275597 4.236701
#> [5,] 4.778865 5.293231 4.905567
#> [6,] 4.318004 4.127986 4.006598
#> [7,] 4.300391 5.030717 4.903505
#> [8,] 4.661448 4.457907 4.281649
#> [9,] 4.503914 4.146758 4.095258
#> [10,] 4.388454 4.123436 3.915876
#> [11,] 4.462818 4.224687 4.339794
#> [12,] 4.447162 3.922355 4.049072
#> [13,] 4.430528 4.357509 4.314639
#> [14,] 4.139922 4.492890 4.272165
#> [15,] 4.276908 3.957622 4.035876
#> [16,] 4.417808 4.054608 4.025567
#> CAAGATCTCTTTAGGG-r17 CAAGGCCGTCAATACC-r17 CAAGGCCGTCCGACGT-r17
#> [1,] 4.296852 4.223529 4.416513
#> [2,] 3.831477 4.828235 3.507086
#> [3,] 4.193220 4.130588 4.096118
#> [4,] 3.922034 3.955294 4.250770
#> [5,] 5.099274 4.384706 5.326556
#> [6,] 4.013075 3.485882 3.734442
#> [7,] 4.532203 4.158824 5.062230
#> [8,] 4.452300 5.485882 4.167591
#> [9,] 3.979177 4.067059 4.027110
#> [10,] 4.199031 4.105882 3.801602
#> [11,] 4.050363 4.641176 4.042514
#> [12,] 4.137530 4.067059 3.959335
#> [13,] 4.152542 3.868235 4.187307
#> [14,] 4.224697 4.715294 4.441158
#> [15,] 4.174334 4.030588 3.781269
#> [16,] 4.474092 4.289412 3.950092
#> CAAGTTGCATTGCGGC-r17 CACAAACGTGATGTGG-r17 CACAAACTCGACAGCC-r17
#> [1,] 4.387251 4.236458 4.128300
#> [2,] 3.737288 3.909179 4.005525
#> [3,] 4.158438 4.149530 3.949048
#> [4,] 4.452100 4.243270 4.286065
#> [5,] 5.057111 4.935777 4.829957
#> [6,] 4.015844 3.951670 3.979742
#> [7,] 4.812454 4.661369 4.802333
#> [8,] 4.261606 4.235161 4.397176
#> [9,] 4.076271 3.991891 4.315531
#> [10,] 4.122329 3.951022 4.314917
#> [11,] 4.212233 4.296464 3.995089
#> [12,] 4.028740 4.181641 4.379374
#> [13,] 4.159912 4.367824 4.255371
#> [14,] 4.394620 4.194940 4.017802
#> [15,] 4.054164 4.081414 4.208717
#> [16,] 4.060427 4.077198 4.144874
#> CACACAAAGAGGACGG-r17 CACACAACAGCGTCCA-r17 CACCTTGAGGAGTTGC-r17
#> [1,] 4.445307 4.274650 4.751548
#> [2,] 4.230769 3.983623 4.414087
#> [3,] 4.360621 4.319686 4.277864
#> [4,] 4.511644 4.157967 4.426471
#> [5,] 4.363444 4.854657 4.694272
#> [6,] 4.009880 4.088707 4.534056
#> [7,] 4.216655 4.800068 4.322755
#> [8,] 4.694425 4.554077 4.783282
#> [9,] 4.471418 4.395769 4.322755
#> [10,] 4.100212 4.147390 5.059598
#> [11,] 4.199012 4.393040 4.595975
#> [12,] 4.297812 4.174343 4.264706
#> [13,] 4.272406 4.051859 4.514706
#> [14,] 4.397318 4.506994 3.995356
#> [15,] 4.079040 3.955647 3.881579
#> [16,] 4.335921 4.132719 4.479102
#> CACTCCAGTCTCATCC-r17 CACTCCATCCTGCTTG-r17 CAGAATCGTCGAGATG-r17
#> [1,] 4.259459 4.211429 4.291233
#> [2,] 4.533591 4.463673 4.072049
#> [3,] 4.293436 4.422041 4.116753
#> [4,] 4.138996 4.260408 4.351128
#> [5,] 4.665637 4.846531 5.230035
#> [6,] 4.307336 4.095510 4.054253
#> [7,] 4.479537 4.287347 4.758681
#> [8,] 4.873359 4.804898 4.319878
#> [9,] 4.395367 4.698776 3.948351
#> [10,] 4.254826 4.407347 4.002604
#> [11,] 4.348263 4.111020 3.975260
#> [12,] 4.292664 4.782041 4.285590
#> [13,] 4.207722 4.404898 4.295139
#> [14,] 4.236293 4.318367 4.243490
#> [15,] 4.088803 4.170612 4.030382
#> [16,] 4.585328 4.591020 4.092448
#> CAGCAGCAGGGCTTGA-r17 CAGCAGCTCATGTCTT-r17 CAGCAGCTCCAAGCCG-r17
#> [1,] 4.244505 4.411781 4.413074
#> [2,] 4.427885 3.975778 4.478442
#> [3,] 4.092033 3.996697 3.895688
#> [4,] 4.378434 4.254886 4.141864
#> [5,] 4.684066 5.207267 4.354659
#> [6,] 4.302885 4.253785 4.549374
#> [7,] 4.492445 4.959538 4.424200
#> [8,] 4.695055 4.663088 4.634214
#> [9,] 4.460852 4.161024 4.745480
#> [10,] 4.493819 3.988439 4.858136
#> [11,] 4.376374 4.253785 4.688456
#> [12,] 4.304258 4.252133 4.539638
#> [13,] 4.327610 4.096890 4.432545
#> [14,] 4.360577 4.293972 4.287900
#> [15,] 4.423764 3.932012 4.232267
#> [16,] 4.497253 4.167905 4.428373
#> CAGCAGCTCTGGTATG-r17 CAGCATAAGCCTATGT-r17 CAGCATAGTAGCTCCG-r17
#> [1,] 4.409809 4.288503 4.407335
#> [2,] 4.286104 4.433116 3.802227
#> [3,] 4.079019 4.384671 4.043877
#> [4,] 3.936785 4.285611 4.283890
#> [5,] 5.186921 4.723789 5.208579
#> [6,] 4.551499 4.266811 4.188933
#> [7,] 4.559673 4.468547 4.981663
#> [8,] 4.904087 4.784526 4.380812
#> [9,] 4.294278 4.352856 4.152914
#> [10,] 3.993460 4.449024 3.909954
#> [11,] 4.244687 4.239335 4.168304
#> [12,] 4.437057 4.685466 3.925344
#> [13,] 4.218529 4.211858 4.222331
#> [14,] 4.327520 4.207520 4.479371
#> [15,] 4.137330 4.470716 3.881139
#> [16,] 4.582561 4.616052 3.928291
#> CAGCATATCTGTCCGT-r17 CAGCGACGTGGTAACG-r17 CAGCTAACATTCACTT-r17
#> [1,] 4.257216 4.163748 4.308562
#> [2,] 4.133419 4.094863 4.010455
#> [3,] 4.220654 4.100117 3.971743
#> [4,] 4.325850 4.299475 4.150890
#> [5,] 5.185375 5.136602 5.244137
#> [6,] 4.101347 4.179218 3.975134
#> [7,] 4.602951 4.959720 5.038994
#> [8,] 4.508659 4.647402 4.475558
#> [9,] 4.252726 4.168418 4.138740
#> [10,] 3.999359 3.987157 4.137609
#> [11,] 4.169339 4.395505 4.294151
#> [12,] 4.096216 3.819907 3.904775
#> [13,] 4.229634 4.092236 4.195818
#> [14,] 4.445799 4.601284 4.441085
#> [15,] 4.234124 3.943958 3.960723
#> [16,] 4.085311 3.983363 4.038429
#> CAGCTAAGTGCACTTA-r17 CAGTAACCACGAGGTA-r17 CAGTAACGTCCCTTGT-r17
#> [1,] 4.234881 4.528837 4.315914
#> [2,] 3.792723 4.240469 4.054981
#> [3,] 4.058720 4.242424 4.164761
#> [4,] 4.061731 4.084066 4.463255
#> [5,] 4.972396 5.297165 4.984576
#> [6,] 4.095107 4.545455 4.054981
#> [7,] 4.747804 4.668622 4.988024
#> [8,] 4.200000 4.736070 4.399202
#> [9,] 4.166374 4.105572 4.213210
#> [10,] 4.065496 4.481916 4.033569
#> [11,] 4.331995 4.309873 4.111776
#> [12,] 4.187704 4.635386 4.090909
#> [13,] 4.335508 3.872923 4.137725
#> [14,] 4.260226 4.114370 4.625113
#> [15,] 4.041907 4.362659 3.798948
#> [16,] 4.034379 4.743891 4.086917
#> CAGTCCTCAAACGCGA-r17 CAGTCCTCATTCCTGC-r17 CATATGGCAGACAAAT-r17
#> [1,] 4.393906 4.686254 4.308596
#> [2,] 3.973935 4.252886 4.054955
#> [3,] 3.824156 4.460651 4.190230
#> [4,] 4.271292 4.119622 4.157821
#> [5,] 5.315712 4.806925 4.609206
#> [6,] 4.063877 4.506821 4.075622
#> [7,] 5.250367 4.447009 4.354157
#> [8,] 4.328561 4.712487 4.522781
#> [9,] 4.102423 4.047219 4.565054
#> [10,] 4.136197 4.429171 4.429779
#> [11,] 4.008076 4.235047 4.022546
#> [12,] 4.107562 4.604407 4.309065
#> [13,] 4.279001 4.533054 4.374824
#> [14,] 4.144640 4.130115 4.630343
#> [15,] 4.160793 4.142707 4.172851
#> [16,] 4.021292 4.498426 4.180366
#> CATATGGGTATTCGTG-r17 CATATGGGTGCGCTTG-r17 CATATTCAGCTAGGCA-r17
#> [1,] 4.179268 4.159377 4.199399
#> [2,] 4.075610 4.523068 4.132132
#> [3,] 4.235772 4.033553 4.057658
#> [4,] 4.271951 4.004194 4.092192
#> [5,] 4.980081 4.923307 5.276577
#> [6,] 4.255285 4.422409 4.312913
#> [7,] 4.899593 4.191732 5.002703
#> [8,] 4.516667 4.834032 4.790090
#> [9,] 4.385772 4.725584 4.057958
#> [10,] 4.161382 4.800479 4.158258
#> [11,] 4.399187 4.005992 4.313514
#> [12,] 4.150813 4.383463 4.046547
#> [13,] 4.115447 3.864590 4.144745
#> [14,] 4.639431 4.272019 4.184084
#> [15,] 4.113415 4.657280 4.045045
#> [16,] 4.049593 4.110246 4.019219
#> CATATTCGTTGGGACA-r17 CATATTCTCATGTGGT-r17 CATCAAGAGAACAACT-r17
#> [1,] 4.051913 4.200000 4.336123
#> [2,] 4.004098 4.317681 4.404463
#> [3,] 4.381148 4.409855 4.357043
#> [4,] 4.209699 4.357101 4.192469
#> [5,] 4.669399 4.896232 4.841004
#> [6,] 4.297814 4.297971 3.959554
#> [7,] 4.271175 4.440580 4.386332
#> [8,] 4.660519 4.689275 5.019526
#> [9,] 4.284836 4.339130 4.259414
#> [10,] 4.206284 4.177971 4.133891
#> [11,] 4.325820 4.250435 4.474198
#> [12,] 4.549180 4.716522 4.149233
#> [13,] 4.215164 4.466087 4.245467
#> [14,] 4.093579 4.206377 4.425384
#> [15,] 4.376366 4.213913 4.112971
#> [16,] 4.449454 4.547826 4.262204
#> CATCAAGCAGTGGGAT-r17 CATCAAGTCTACTCAT-r17 CATCAGAAGATGTAAC-r17
#> [1,] 4.214798 4.217255 4.482692
#> [2,] 3.794036 4.353725 3.874607
#> [3,] 4.194920 4.077647 4.056403
#> [4,] 4.256212 4.121569 3.953280
#> [5,] 5.151298 4.541176 5.227548
#> [6,] 3.927112 4.338039 4.163641
#> [7,] 4.914964 4.610196 4.798354
#> [8,] 4.293760 4.748235 4.232389
#> [9,] 4.098288 4.536471 3.941661
#> [10,] 3.957482 4.651765 4.053498
#> [11,] 4.600221 4.127843 4.140886
#> [12,] 4.177250 4.385882 4.261438
#> [13,] 4.051353 4.130196 4.229000
#> [14,] 4.420210 4.181176 4.100218
#> [15,] 3.785754 4.414902 3.943597
#> [16,] 4.109332 4.405490 4.148148
#> CATCAGAGTTCGGGCT-r17 CATCCACCATCCGTGG-r17 CATCGAAAGAATAGGG-r17
#> [1,] 4.147390 4.340533 4.201507
#> [2,] 4.358240 4.339813 4.288763
#> [3,] 4.233367 4.121670 3.937853
#> [4,] 4.574207 3.924406 4.040176
#> [5,] 4.293756 4.889129 5.126177
#> [6,] 4.427840 3.940965 4.039548
#> [7,] 4.456499 4.224622 4.799749
#> [8,] 5.096213 4.891289 4.694915
#> [9,] 4.298874 4.053276 4.290019
#> [10,] 4.400205 4.110871 3.926554
#> [11,] 4.480041 4.504680 4.231638
#> [12,] 4.416581 3.754500 3.814815
#> [13,] 4.357216 3.979842 4.024482
#> [14,] 4.243603 4.364291 4.798493
#> [15,] 4.209826 3.820734 3.756434
#> [16,] 4.229273 4.375810 4.019460
#> CATGACATCTTCAACT-r17 CATGCCTAGAAGCCCA-r17 CATGGCGAGTCGATAA-r17
#> [1,] 4.722541 4.458868 4.622052
#> [2,] 3.955889 4.018113 3.703420
#> [3,] 4.022938 4.370566 4.250590
#> [4,] 4.425232 4.068679 4.119693
#> [5,] 5.077636 4.550189 4.691038
#> [6,] 4.010587 4.049057 4.187500
#> [7,] 4.616674 4.493585 4.625590
#> [8,] 4.494486 4.591698 4.268868
#> [9,] 4.119541 4.276981 4.244104
#> [10,] 3.820468 4.097358 4.071344
#> [11,] 4.206881 4.264151 4.573113
#> [12,] 3.940009 4.175849 4.347877
#> [13,] 4.161447 4.366792 4.438679
#> [14,] 4.489193 4.289057 4.241156
#> [15,] 3.915307 4.440755 4.124410
#> [16,] 4.171151 4.157736 3.962264
#> CATTATCAGAAGCCCA-r17 CATTCGCCAAGCGTAG-r17 CATTCGCCACATCCGG-r17
#> [1,] 4.236497 4.492378 4.197424
#> [2,] 4.141898 3.887195 4.168937
#> [3,] 4.145094 4.039634 4.352985
#> [4,] 4.241611 4.416667 4.422839
#> [5,] 5.084692 4.792683 4.889770
#> [6,] 4.204538 4.158028 4.139955
#> [7,] 4.847875 4.716463 4.674758
#> [8,] 4.431448 4.355691 4.491949
#> [9,] 4.253755 4.252033 4.133515
#> [10,] 4.197507 4.194614 4.103542
#> [11,] 4.183445 4.108740 4.552886
#> [12,] 4.067434 4.133638 4.144166
#> [13,] 4.235219 4.209858 4.051028
#> [14,] 4.183126 4.396341 4.419123
#> [15,] 4.170022 3.989837 3.961110
#> [16,] 4.295622 4.201728 4.153827
#> CATTCGCTCGCCGTGA-r17 CCAATCCAGGTGGGTT-r17 CCACCTACATCACAAC-r17
#> [1,] 4.520983 4.010616 4.241085
#> [2,] 3.769784 4.595895 4.229457
#> [3,] 4.124101 4.478415 4.406589
#> [4,] 4.364508 4.348903 4.262016
#> [5,] 4.920863 4.764331 5.054264
#> [6,] 4.071942 4.160651 4.150000
#> [7,] 4.591727 4.600849 4.743411
#> [8,] 4.395683 4.662420 4.304264
#> [9,] 4.030576 4.101203 4.065116
#> [10,] 4.173261 4.202406 4.295349
#> [11,] 4.089928 4.573248 4.343798
#> [12,] 4.297362 4.177636 4.185271
#> [13,] 4.209233 3.970276 4.542248
#> [14,] 4.265588 4.569002 4.388760
#> [15,] 4.167866 3.869073 3.896899
#> [16,] 3.960432 4.224345 4.110465
#> CCACCTATCGCGCCAA-r17 CCACGGAAGGACGAAA-r17 CCACGGAGTGATAAAC-r17
#> [1,] 4.274433 4.333047 4.336735
#> [2,] 4.107897 4.494421 3.746939
#> [3,] 4.180610 3.865236 4.213265
#> [4,] 4.054730 4.003433 4.038776
#> [5,] 4.700547 4.982833 4.960204
#> [6,] 4.405004 4.425751 3.827551
#> [7,] 4.357310 4.219742 4.721429
#> [8,] 4.698202 5.040343 4.463265
#> [9,] 4.530102 4.403433 4.311224
#> [10,] 4.374511 4.354506 4.228571
#> [11,] 4.258014 4.222318 4.501020
#> [12,] 4.465989 4.449785 4.378571
#> [13,] 4.301798 4.103004 4.361224
#> [14,] 4.351837 4.366524 4.520408
#> [15,] 4.093041 4.221459 3.826531
#> [16,] 4.476153 4.597425 4.166327
#> CCATGTCAGCTAGTTC-r17 CCATGTCTCGATGAGG-r17 CCATTCGCATTGGCGC-r17
#> [1,] 4.421782 4.124671 4.235873
#> [2,] 4.566337 4.504997 4.028254
#> [3,] 4.364356 4.232509 4.165714
#> [4,] 4.536634 4.132562 4.247619
#> [5,] 4.605941 4.954761 5.202222
#> [6,] 4.503960 3.865860 4.008254
#> [7,] 4.055446 4.640189 4.865714
#> [8,] 4.993069 4.943714 4.193651
#> [9,] 4.241584 4.179379 4.089524
#> [10,] 4.290099 3.947396 3.906984
#> [11,] 4.463366 4.411888 4.074921
#> [12,] 4.300000 3.945292 4.125397
#> [13,] 4.452475 3.875855 4.344127
#> [14,] 3.988119 4.755392 4.324762
#> [15,] 4.392079 3.889532 4.161270
#> [16,] 4.307921 3.990531 4.311111
#> CCATTCGTCTTGCCGT-r17 CCCAATCTCCTGCTTG-r17 CCCTCCTAGTATCGAA-r17
#> [1,] 4.412807 4.319231 4.373186
#> [2,] 4.029160 3.544872 3.740569
#> [3,] 4.408805 3.998718 4.183401
#> [4,] 3.945111 4.293590 4.245502
#> [5,] 4.465981 5.280769 5.189785
#> [6,] 4.341910 4.296154 3.886245
#> [7,] 4.454545 4.538462 4.496228
#> [8,] 4.634648 4.414103 4.342426
#> [9,] 4.192110 3.853846 4.058038
#> [10,] 4.283019 4.256410 4.048172
#> [11,] 4.495140 3.841026 4.107951
#> [12,] 4.388222 4.033333 4.244341
#> [13,] 4.272727 4.482051 4.233894
#> [14,] 4.202401 4.142308 4.102147
#> [15,] 4.276730 3.778205 3.918746
#> [16,] 4.354488 3.651282 4.088799
#> CCCTCCTTCTACTCAT-r17 CCGGGATCAAGCGATG-r17 CCGTACTGTGACTACT-r17
#> [1,] 4.185869 4.425655 4.298711
#> [2,] 4.353275 4.013482 4.093123
#> [3,] 4.196876 4.283128 4.205587
#> [4,] 4.477188 4.275809 4.264327
#> [5,] 4.913900 4.905239 4.836676
#> [6,] 4.145571 3.988059 3.718481
#> [7,] 4.644772 4.904854 4.568768
#> [8,] 4.523522 4.259630 4.590974
#> [9,] 4.243742 3.963405 4.124642
#> [10,] 4.208415 3.962635 3.891117
#> [11,] 4.291852 4.174884 4.204871
#> [12,] 4.223682 4.088213 3.893266
#> [13,] 4.103675 4.243066 3.950573
#> [14,] 4.661282 4.329353 4.628223
#> [15,] 3.760341 4.030046 3.643983
#> [16,] 4.312977 4.029276 4.169054
#> CCGTTCATCACGAAGG-r17 CCTAGCTTCTTAGCCC-r17 CCTATTACACCAACCG-r17
#> [1,] 4.429855 4.539411 4.475490
#> [2,] 3.955652 4.096866 4.143382
#> [3,] 4.091014 4.735992 4.151961
#> [4,] 4.199420 4.225071 4.225490
#> [5,] 5.097971 4.858500 4.742647
#> [6,] 4.097681 4.539411 4.145833
#> [7,] 4.862319 4.555556 4.507353
#> [8,] 4.491884 4.884141 4.995098
#> [9,] 4.191884 4.223172 4.332108
#> [10,] 4.234203 4.481481 4.582108
#> [11,] 4.223478 4.585945 4.339461
#> [12,] 4.235072 4.644824 4.542892
#> [13,] 4.202899 4.141500 4.632353
#> [14,] 4.461159 4.245014 4.526961
#> [15,] 4.068116 4.264957 4.577206
#> [16,] 4.065797 4.356125 4.322304
#> CCTCAGTTCTGATACG-r17 CCTCTGAGTACAGCAG-r17 CCTCTGAGTCTCACCT-r17
#> [1,] 4.614048 4.296788 4.418810
#> [2,] 3.875378 4.242525 4.308682
#> [3,] 3.706193 4.122924 4.226688
#> [4,] 3.871601 4.184939 4.412379
#> [5,] 5.125378 4.695460 4.497588
#> [6,] 3.805136 4.302326 4.329582
#> [7,] 4.913142 4.169435 4.500804
#> [8,] 4.699396 4.594684 4.631029
#> [9,] 4.163897 4.636766 4.512862
#> [10,] 3.886707 4.420819 4.311093
#> [11,] 4.150302 4.383167 4.371383
#> [12,] 4.003776 4.452935 4.561897
#> [13,] 4.077795 4.358804 4.491158
#> [14,] 4.697885 4.383167 4.226688
#> [15,] 3.734139 3.935770 4.300643
#> [16,] 4.216767 4.482835 4.475080
#> CCTTACGCAGACAGGT-r17 CCTTCCCGTACAGTTC-r17 CCTTCGACATTGCGGC-r17
#> [1,] 4.200000 4.184130 4.348506
#> [2,] 4.457732 4.229167 4.036136
#> [3,] 3.848454 4.157935 4.058721
#> [4,] 4.043299 4.369792 4.212648
#> [5,] 4.594845 4.986979 5.029187
#> [6,] 4.223711 4.176930 4.181028
#> [7,] 4.422680 4.797028 4.881515
#> [8,] 4.920619 4.343750 4.628909
#> [9,] 4.652577 4.225797 4.323489
#> [10,] 4.429897 4.208487 3.963864
#> [11,] 4.445361 4.282629 4.246004
#> [12,] 4.271134 4.157169 4.047603
#> [13,] 4.292784 4.286305 4.156011
#> [14,] 4.330928 4.506893 4.511119
#> [15,] 4.003093 3.967984 4.120917
#> [16,] 4.560825 4.264706 4.315497
#> CCTTTCTAGACGCTTT-r17 CGAACATGTCCCGACA-r17 CGAATGTCAAACGTGG-r17
#> [1,] 4.495693 4.478377 4.518993
#> [2,] 4.070245 4.097139 3.734099
#> [3,] 4.423459 4.106454 4.100707
#> [4,] 4.375083 3.962076 4.214223
#> [5,] 5.043738 4.997339 4.834364
#> [6,] 4.369119 3.763806 3.858657
#> [7,] 4.364480 4.655356 4.627650
#> [8,] 4.783300 4.859614 4.367049
#> [9,] 4.545394 4.203593 4.045053
#> [10,] 4.357190 3.890220 3.856007
#> [11,] 4.434062 4.261477 4.068021
#> [12,] 4.277667 3.860945 4.263693
#> [13,] 4.269715 3.937458 4.213339
#> [14,] 4.277667 4.634731 4.162102
#> [15,] 4.180915 3.846973 4.467314
#> [16,] 4.473161 4.389222 4.408127
#> CGAATGTGTTCTGTTT-r17 CGAATGTTCTTGCAAG-r17 CGACCTTAGGCTCAGA-r17
#> [1,] 4.024984 4.062806 4.430914
#> [2,] 4.310058 4.670473 3.750718
#> [3,] 4.167841 4.327080 4.254203
#> [4,] 4.158873 4.335237 4.230012
#> [5,] 4.618834 4.867863 5.155392
#> [6,] 4.281230 3.822186 3.996720
#> [7,] 4.224856 4.732463 4.902829
#> [8,] 4.832159 4.849103 4.432964
#> [9,] 4.151826 4.380098 4.329643
#> [10,] 4.551570 3.836868 3.899959
#> [11,] 4.244074 4.386623 4.303403
#> [12,] 4.188341 4.013866 4.114801
#> [13,] 4.176810 4.260196 4.156622
#> [14,] 4.372197 4.480424 4.636736
#> [15,] 4.095452 3.981240 4.097581
#> [16,] 4.343370 4.075856 3.952440
#> CGACCTTAGTGACATA-r17 CGACCTTTCAACGCTA-r17 CGACTTCTCGTGGTCG-r17
#> [1,] 4.272727 4.246364 4.327328
#> [2,] 4.310421 4.166364 4.317627
#> [3,] 4.074279 3.964545 4.489745
#> [4,] 4.231707 4.342727 4.317073
#> [5,] 4.302661 4.570909 4.692905
#> [6,] 4.375831 4.207273 4.127494
#> [7,] 4.233925 4.620909 4.444290
#> [8,] 4.715078 4.806364 4.711197
#> [9,] 4.161863 4.480000 4.190965
#> [10,] 4.728381 4.434545 4.032428
#> [11,] 4.486696 4.320909 4.416020
#> [12,] 4.291574 4.340909 4.453437
#> [13,] 4.207317 4.649091 4.267461
#> [14,] 4.256098 4.273636 4.466463
#> [15,] 4.041020 4.223636 4.218681
#> [16,] 4.369180 4.464545 4.353936
#> CGAGAAGTCGGATGTT-r17 CGAGCACAGAGTACAT-r17 CGAGCCAAGCACACAG-r17
#> [1,] 4.438413 4.505095 4.413842
#> [2,] 4.276618 4.276565 4.277542
#> [3,] 4.339248 4.142649 4.128531
#> [4,] 4.308977 4.157205 4.293079
#> [5,] 4.643006 4.701601 4.937853
#> [6,] 4.283925 4.202329 4.202684
#> [7,] 4.434238 4.187773 4.525424
#> [8,] 4.597077 4.976710 4.743644
#> [9,] 4.278706 4.726346 4.558616
#> [10,] 4.277662 4.576419 4.225989
#> [11,] 4.401879 4.177584 4.091808
#> [12,] 4.121086 4.569141 4.511299
#> [13,] 4.260960 4.614265 4.067090
#> [14,] 4.512526 4.179039 4.351695
#> [15,] 3.939457 3.857351 4.452684
#> [16,] 4.097077 4.315866 4.194209
#> CGAGCCATCGGTCCGA-r17 CGAGCCATCTACTTAC-r17 CGATCGGGTAGCTCCG-r17
#> [1,] 4.201835 4.657676 4.259476
#> [2,] 4.341743 5.294606 4.056703
#> [3,] 4.614679 4.447095 4.072727
#> [4,] 4.212156 3.974066 4.248074
#> [5,] 4.658257 4.575726 5.145455
#> [6,] 4.136468 5.349585 4.164253
#> [7,] 4.488532 4.082988 4.895840
#> [8,] 4.787844 4.185685 4.452080
#> [9,] 4.579128 3.884855 4.008012
#> [10,] 4.193807 4.268672 4.043451
#> [11,] 4.451835 4.329876 4.303544
#> [12,] 4.385321 5.019710 4.023421
#> [13,] 4.209862 4.232365 4.067488
#> [14,] 4.465596 4.102697 4.323575
#> [15,] 4.233945 4.010373 3.942373
#> [16,] 4.629587 4.201245 4.270570
#> CGATTGATCAGGTTCA-r17 CGATTGATCGATGAGG-r17 CGCCAAGAGTTCGCAT-r17
#> [1,] 4.214193 3.941667 4.272227
#> [2,] 4.203125 4.255952 4.237608
#> [3,] 4.566406 4.413095 4.164437
#> [4,] 4.119792 4.222619 4.435877
#> [5,] 4.611979 4.465476 4.472856
#> [6,] 4.103516 4.165476 4.107789
#> [7,] 4.307943 4.380952 4.305271
#> [8,] 4.444661 4.758333 4.805665
#> [9,] 4.346354 4.503571 4.122738
#> [10,] 4.451823 4.266667 4.789142
#> [11,] 4.190104 4.235714 4.283242
#> [12,] 4.413411 4.336905 4.468922
#> [13,] 4.285807 4.239286 4.413061
#> [14,] 4.145833 4.179762 4.022030
#> [15,] 4.358724 4.214286 4.571204
#> [16,] 4.296875 4.477381 4.435877
#> CGCCAAGCAAATACAG-r17 CGCCAAGGTAGAGGAA-r17 CGCGTTTTCAGTTGAC-r17
#> [1,] 4.268817 4.254517 4.330352
#> [2,] 4.096102 4.457973 3.920054
#> [3,] 4.041667 4.174391 4.087263
#> [4,] 4.286962 4.502749 4.011111
#> [5,] 5.014113 5.103692 5.298374
#> [6,] 4.270161 4.460330 4.000542
#> [7,] 4.706317 4.423409 5.108401
#> [8,] 4.240591 4.776905 4.237940
#> [9,] 4.067204 4.484682 3.986179
#> [10,] 4.065860 4.455617 4.073984
#> [11,] 4.116935 4.286724 4.324661
#> [12,] 4.163306 4.572663 4.138482
#> [13,] 4.280914 4.304792 4.186450
#> [14,] 4.469086 4.217596 4.427913
#> [15,] 4.148522 4.216811 3.911653
#> [16,] 4.226478 4.388060 4.100271
#> CGCGTTTTCTAGCACA-r17 CGCTATCCACACTGCG-r17 CGCTATCGTCTAACGT-r17
#> [1,] 4.500000 4.354906 4.342611
#> [2,] 4.090872 4.303758 4.348575
#> [3,] 4.446618 4.417537 4.188204
#> [4,] 4.349226 4.250522 4.276342
#> [5,] 4.708639 4.767223 5.007290
#> [6,] 3.917685 4.526096 4.027170
#> [7,] 4.379381 4.316284 4.443340
#> [8,] 4.501630 4.824635 4.592445
#> [9,] 4.517115 4.470772 4.180915
#> [10,] 4.160147 4.351775 4.289596
#> [11,] 4.316626 4.430063 4.116634
#> [12,] 4.290954 4.588727 4.235918
#> [13,] 4.246129 4.111691 4.222001
#> [14,] 4.364303 4.304802 4.158383
#> [15,] 4.023635 4.388309 4.265739
#> [16,] 4.300326 4.680585 4.357190
#> CGCTATCGTTCAGACT-r17 CGCTGGATCGGCTACG-r17 CGCTTCACACCATGTA-r17
#> [1,] 4.534937 4.358605 4.342561
#> [2,] 4.349370 4.079767 4.285813
#> [3,] 4.263459 4.095814 4.326644
#> [4,] 4.104238 4.179535 4.515571
#> [5,] 4.378007 5.181163 4.403460
#> [6,] 4.279496 4.124651 4.388927
#> [7,] 4.650630 4.701628 4.338408
#> [8,] 4.647194 4.328140 4.913495
#> [9,] 4.206186 4.091860 4.429758
#> [10,] 4.331042 4.159302 4.707958
#> [11,] 4.372279 4.131628 4.585467
#> [12,] 4.578465 4.037674 4.631834
#> [13,] 4.335624 4.288372 4.196540
#> [14,] 4.269187 4.382093 4.205536
#> [15,] 4.258877 4.119767 4.417993
#> [16,] 4.248568 4.145116 4.516955
#> CGCTTCATCTGTCAAG-r17 CGGACACAGAGCTGGT-r17 CGGACACCACAGTCGC-r17
#> [1,] 4.355664 4.313736 4.109064
#> [2,] 4.410475 4.492785 4.340457
#> [3,] 4.193666 4.133618 4.210022
#> [4,] 4.238733 3.908605 4.112749
#> [5,] 4.587089 5.157670 4.602063
#> [6,] 3.809988 4.437734 4.007369
#> [7,] 4.465286 4.687333 4.547531
#> [8,] 4.809988 4.725815 4.567428
#> [9,] 4.118149 4.544629 4.568165
#> [10,] 4.125457 4.458578 4.660280
#> [11,] 3.829476 4.155532 4.298452
#> [12,] 4.306943 4.383218 4.761975
#> [13,] 4.322777 3.965794 4.599853
#> [14,] 4.304507 4.351684 4.053058
#> [15,] 4.247259 4.092998 4.688283
#> [16,] 4.478685 4.396045 4.435520
#> CGGACGTAGGCCATAG-r17 CGGACTGCATTGAGCT-r17 CGGACTGGTAAGTGGC-r17
#> [1,] 4.203226 4.187661 4.403252
#> [2,] 4.612903 4.363753 4.246341
#> [3,] 4.325806 4.299486 4.200813
#> [4,] 4.209677 4.105398 4.181301
#> [5,] 4.421505 4.359897 4.771138
#> [6,] 3.972043 4.251928 4.105285
#> [7,] 4.600000 4.551414 4.399187
#> [8,] 4.644086 4.460154 4.795122
#> [9,] 4.297849 4.589974 4.526423
#> [10,] 4.380645 4.383033 4.347154
#> [11,] 4.519355 4.259640 4.310569
#> [12,] 4.517204 4.154242 4.447561
#> [13,] 4.225806 4.457584 4.429675
#> [14,] 4.402151 4.320051 4.250407
#> [15,] 4.177419 4.050129 4.226423
#> [16,] 4.434409 4.790488 4.365854
#> CGGACTGGTGGACGAT-r17 CGGAGCTAGGGTATCG-r17 CGGAGCTTCGGTCCGA-r17
#> [1,] 4.135047 4.424309 4.207809
#> [2,] 4.061466 4.507182 4.373426
#> [3,] 4.256501 4.471823 4.297859
#> [4,] 4.244976 4.384530 4.241814
#> [5,] 4.919031 4.301657 4.756297
#> [6,] 4.015071 4.065193 3.962217
#> [7,] 4.761229 4.686188 4.738665
#> [8,] 4.543144 4.908287 4.715365
#> [9,] 4.159574 4.356906 4.259446
#> [10,] 4.122931 4.202210 4.007557
#> [11,] 4.231087 4.360221 4.246851
#> [12,] 4.196809 4.404420 4.068640
#> [13,] 4.130910 4.239779 4.054786
#> [14,] 4.326832 4.424309 4.392947
#> [15,] 4.008274 4.248619 4.020781
#> [16,] 4.338948 4.523757 3.967254
#> CGGCTAGCATCAGTAC-r17 CGGTTAAAGTCAAGGC-r17 CGGTTAATCACTCCTG-r17
#> [1,] 4.326337 4.482134 4.445329
#> [2,] 3.787068 3.945143 3.894464
#> [3,] 4.238659 4.229995 4.177509
#> [4,] 4.130670 4.089079 4.028720
#> [5,] 5.204807 4.973327 5.088581
#> [6,] 3.999661 3.794665 3.891349
#> [7,] 5.011171 4.769502 4.871972
#> [8,] 4.473934 4.378460 4.204844
#> [9,] 3.991875 4.088576 3.878547
#> [10,] 3.873392 4.165576 3.942561
#> [11,] 4.076168 4.326120 4.425606
#> [12,] 4.160460 4.100654 4.192734
#> [13,] 4.301625 4.181178 4.266090
#> [14,] 4.486798 4.412682 4.221107
#> [15,] 4.269465 4.304479 4.068858
#> [16,] 4.233243 4.608958 4.113841
#> CGTAGGCAGGTGATTA-r17 CGTAGGCGTGTTGAGG-r17 CGTCACTAGTGCGATG-r17
#> [1,] 4.254130 4.301676 4.279570
#> [2,] 4.202033 4.048990 4.249010
#> [3,] 4.466328 3.967340 4.200905
#> [4,] 4.115629 4.205415 4.244482
#> [5,] 4.614994 5.287924 5.304471
#> [6,] 4.055909 4.029222 3.989813
#> [7,] 4.665820 5.015900 4.904924
#> [8,] 4.817027 4.473141 4.304471
#> [9,] 4.547649 3.886979 3.898132
#> [10,] 4.529860 3.954878 3.980758
#> [11,] 4.620076 4.148689 4.146576
#> [12,] 4.659466 4.003438 4.102999
#> [13,] 4.637865 4.156854 4.232032
#> [14,] 4.087675 4.666953 4.204867
#> [15,] 4.606099 3.822089 3.957555
#> [16,] 4.143583 4.055866 4.093945
#> CGTCACTAGTGTCTCA-r17 CGTCAGGTCGCTAGCG-r17 CGTCTACCACCAACCG-r17
#> [1,] 4.497650 4.157552 4.125000
#> [2,] 3.747258 4.032552 4.466102
#> [3,] 4.078329 4.117839 4.458333
#> [4,] 4.233943 4.292969 4.170198
#> [5,] 4.913316 5.065755 4.342514
#> [6,] 4.098172 4.323568 3.916667
#> [7,] 4.867363 4.743490 4.305791
#> [8,] 4.438642 4.389974 4.908192
#> [9,] 4.141514 4.162760 4.465395
#> [10,] 4.050131 4.118490 4.228107
#> [11,] 4.190078 4.207682 4.519068
#> [12,] 4.033420 4.268880 4.269068
#> [13,] 4.291384 4.218750 4.215395
#> [14,] 4.600000 4.432943 4.034605
#> [15,] 3.859008 3.902995 4.155367
#> [16,] 4.167102 4.055990 4.426554
#> CGTGAGCAGTCTCGGC-r17 CGTGAGCCAAACGTGG-r17 CGTTCTGAGCTAAGAT-r17
#> [1,] 4.246609 4.418415 4.070690
#> [2,] 4.122093 3.968531 4.032759
#> [3,] 4.169574 4.237179 4.351724
#> [4,] 4.347384 4.023310 4.031034
#> [5,] 5.002907 5.033800 4.734483
#> [6,] 4.160853 4.012821 3.884483
#> [7,] 4.996124 4.678904 4.643103
#> [8,] 4.234496 4.583916 4.680172
#> [9,] 3.787791 3.967366 4.247414
#> [10,] 4.030523 4.147436 4.132759
#> [11,] 4.219961 4.110140 4.259483
#> [12,] 4.233043 3.968531 4.456897
#> [13,] 4.272771 4.252914 4.314655
#> [14,] 4.475775 4.132284 4.455172
#> [15,] 4.025194 4.129371 4.197414
#> [16,] 4.087209 4.149767 4.468103
#> CGTTCTGCATGTCTCC-r17 CGTTGGGAGTTGCAGG-r17 CGTTGGGCACCGATAT-r17
#> [1,] 4.354690 4.191822 3.980769
#> [2,] 3.910385 4.145170 4.616516
#> [3,] 4.098827 4.252195 4.018100
#> [4,] 4.248744 4.267563 3.998869
#> [5,] 5.132328 5.112788 4.573529
#> [6,] 4.115159 4.113063 4.260181
#> [7,] 4.955611 4.977497 4.150452
#> [8,] 4.445142 4.557903 4.869910
#> [9,] 4.408291 4.069704 4.263575
#> [10,] 4.060302 4.073546 4.578054
#> [11,] 4.327889 4.242316 4.041855
#> [12,] 4.134422 4.136663 4.532805
#> [13,] 4.202261 4.083425 4.236425
#> [14,] 4.279313 4.423161 4.190045
#> [15,] 3.943467 3.936608 4.170814
#> [16,] 4.064070 4.180296 4.231900
#> CTAAGACGTCACAAGG-r17 CTAATGGAGCCAACAG-r17 CTAATGGCACGTAAGG-r17
#> [1,] 4.171379 4.322793 4.788357
#> [2,] 4.053752 4.329381 3.798150
#> [3,] 4.200000 4.424242 4.173014
#> [4,] 4.439791 4.222661 4.385201
#> [5,] 4.834555 4.507246 4.698585
#> [6,] 4.158115 3.860343 3.973885
#> [7,] 4.680977 4.588933 4.587051
#> [8,] 4.540314 4.584980 4.350925
#> [9,] 4.358813 4.220026 4.076714
#> [10,] 4.353229 3.985507 4.016322
#> [11,] 4.347295 4.173913 4.253536
#> [12,] 4.129145 4.169960 4.270403
#> [13,] 4.064921 4.183136 4.360718
#> [14,] 4.498429 4.310935 4.324266
#> [15,] 4.067016 3.877470 4.006529
#> [16,] 4.203141 4.214756 4.241567
#> CTACACCAGCATGGCA-r17 CTACGTCGTGGGTCAA-r17 CTCACACGTACTCTCC-r17
#> [1,] 4.313653 4.368087 4.441325
#> [2,] 3.787032 4.479601 4.179986
#> [3,] 4.214022 4.300997 4.469402
#> [4,] 4.384818 4.061650 4.484521
#> [5,] 4.752240 4.419764 4.665227
#> [6,] 3.955720 4.403445 4.192945
#> [7,] 4.700580 4.232094 4.375090
#> [8,] 4.303637 4.564823 4.504680
#> [9,] 3.898260 4.426111 4.264939
#> [10,] 4.215076 4.177697 4.221022
#> [11,] 4.057459 4.125113 4.282937
#> [12,] 4.243542 4.465095 4.113031
#> [13,] 4.164997 4.441523 4.290137
#> [14,] 4.224038 4.494107 4.220302
#> [15,] 4.334212 4.016319 4.005040
#> [16,] 4.088034 4.535811 4.233261
#> CTCAGAAAGCTACCGC-r17 CTCGAAAGTCACCTAA-r17 CTCGAAATCACTCCTG-r17
#> [1,] 4.165476 4.380143 4.539879
#> [2,] 3.929762 4.196780 4.013751
#> [3,] 3.997619 4.163685 4.190044
#> [4,] 4.098810 4.399821 4.569307
#> [5,] 4.501190 4.987478 4.628163
#> [6,] 4.266667 3.991950 4.174642
#> [7,] 4.452381 4.859571 4.342134
#> [8,] 4.626190 4.534884 4.701320
#> [9,] 4.516667 4.272809 4.417767
#> [10,] 4.708333 4.075134 4.341584
#> [11,] 4.305952 4.275492 4.312431
#> [12,] 4.620238 4.096601 4.287129
#> [13,] 4.603571 3.983900 4.190044
#> [14,] 4.122619 4.658318 4.488174
#> [15,] 3.845238 4.154741 4.246150
#> [16,] 4.610714 4.247764 4.384488
#> CTCGGAGAGCCAACAG-r17 CTCGGGAAGCCGATTT-r17 CTCGTACGTTGACGTT-r17
#> [1,] 4.444088 4.068689 4.327373
#> [2,] 4.174960 4.151650 4.050894
#> [3,] 4.091493 4.424621 4.096286
#> [4,] 4.367041 4.090098 4.222834
#> [5,] 4.874799 4.582516 5.133425
#> [6,] 4.173355 3.975914 4.414030
#> [7,] 4.471910 4.365745 4.206327
#> [8,] 4.390048 4.746655 4.635488
#> [9,] 4.136437 4.415700 4.398900
#> [10,] 4.058320 4.314005 4.288858
#> [11,] 4.027287 4.143622 4.044017
#> [12,] 3.941680 4.235504 4.324622
#> [13,] 4.315142 4.307761 4.119670
#> [14,] 4.507223 4.172168 4.050894
#> [15,] 4.110219 4.421053 4.323246
#> [16,] 4.039058 4.682426 4.037139
#> CTCGTACTCTCGTATT-r17 CTCGTCAAGCGATAGC-r17 CTCTAATAGTCCGTAT-r17
#> [1,] 4.398443 4.590776 4.457840
#> [2,] 4.019468 3.875657 4.085714
#> [3,] 4.249838 4.389375 4.160976
#> [4,] 4.356262 3.990660 4.234843
#> [5,] 4.755354 4.977817 4.703136
#> [6,] 3.826736 4.274372 4.396516
#> [7,] 4.716418 4.752481 4.183275
#> [8,] 4.282933 4.451255 4.655052
#> [9,] 4.238806 4.169294 4.188153
#> [10,] 4.250487 4.022767 4.421603
#> [11,] 4.155094 4.377116 3.958188
#> [12,] 4.353666 4.375949 4.344251
#> [13,] 4.201817 4.258611 4.528223
#> [14,] 4.524984 4.201401 4.266899
#> [15,] 3.907852 3.896673 4.120557
#> [16,] 4.209604 4.036778 4.321254
#> CTCTACGTCCTGCTTG-r17 CTCTGGTCATGCCACG-r17 CTCTGGTGTAGGCATG-r17
#> [1,] 3.979263 4.116658 4.243283
#> [2,] 4.583717 4.202049 4.052906
#> [3,] 4.374040 4.162112 4.252031
#> [4,] 4.459293 4.463216 4.338679
#> [5,] 4.487711 4.894377 5.075401
#> [6,] 4.003840 4.122964 4.132472
#> [7,] 4.311060 4.650026 4.757342
#> [8,] 5.195084 4.428271 4.618829
#> [9,] 4.437788 4.230688 4.151218
#> [10,] 4.080645 4.251182 4.165174
#> [11,] 4.334101 4.297162 4.223703
#> [12,] 4.268817 4.164740 3.925224
#> [13,] 4.238863 4.257488 4.187461
#> [14,] 4.407834 4.506043 4.477401
#> [15,] 3.881720 4.065423 4.027286
#> [16,] 4.321813 4.339464 4.131014
#> CTCTGGTTCCAGGGCT-r17 CTGAAACCACATGTGT-r17 CTGAAACCATATGCTG-r17
#> [1,] 3.987061 4.141444 3.871605
#> [2,] 3.944547 3.905045 4.671605
#> [3,] 4.222736 4.215134 4.229630
#> [4,] 4.555453 4.243323 4.262963
#> [5,] 4.448244 4.958952 4.567901
#> [6,] 4.052680 4.198813 4.193827
#> [7,] 4.753235 4.611276 4.201235
#> [8,] 4.719963 4.661721 4.648148
#> [9,] 4.490758 4.163205 4.197531
#> [10,] 4.063771 4.277448 4.559259
#> [11,] 4.306839 4.099407 4.261728
#> [12,] 3.984288 3.973788 4.337037
#> [13,] 4.413124 4.235905 4.169136
#> [14,] 4.037893 4.217606 4.339506
#> [15,] 4.006470 4.043521 4.141975
#> [16,] 4.179298 4.149852 4.741975
#> CTGAAGTTCGTACCGG-r17 CTGATAGAGCGTAATA-r17 CTGATAGCACGCGAAA-r17
#> [1,] 4.334041 4.316482 4.178849
#> [2,] 4.130219 3.830093 4.118007
#> [3,] 4.278839 3.976369 4.436913
#> [4,] 3.867657 4.346695 4.255615
#> [5,] 4.872611 5.268023 4.746019
#> [6,] 4.069356 3.906072 4.018375
#> [7,] 4.503892 5.013760 4.440996
#> [8,] 4.656759 4.205205 4.418130
#> [9,] 4.358811 3.897697 4.230706
#> [10,] 4.632696 4.119055 4.323806
#> [11,] 4.305732 4.110679 4.327889
#> [12,] 4.760085 4.090338 4.342589
#> [13,] 4.046001 4.237810 4.337689
#> [14,] 4.095541 4.398145 4.231523
#> [15,] 4.278839 3.917739 4.142099
#> [16,] 4.859873 4.081364 4.220906
#> CTGATAGCAGGCTGAA-r17 CTGCGGAAGTAAGTAC-r17 CTGGTCTGTAATCGTC-r17
#> [1,] 4.386313 4.237224 4.311809
#> [2,] 4.208389 4.067823 4.276323
#> [3,] 4.134658 4.158675 4.268761
#> [4,] 3.822075 4.224921 4.124491
#> [5,] 4.891391 5.398738 4.782432
#> [6,] 4.165563 4.004416 4.302501
#> [7,] 4.097130 4.779495 4.431646
#> [8,] 4.624724 4.459306 4.659104
#> [9,] 4.539514 4.015773 4.403723
#> [10,] 4.154525 4.084543 4.305992
#> [11,] 4.374834 4.162461 4.470041
#> [12,] 4.237969 4.136278 4.305992
#> [13,] 4.509051 4.188013 4.257126
#> [14,] 4.299779 4.371293 4.349622
#> [15,] 3.992053 4.026814 3.938336
#> [16,] 4.355408 4.374763 4.375800
#> CTGTGCTCATCACGAT-r17 CTGTTTATCACTCCTG-r17 CTTAACTCAAGCCGCT-r17
#> [1,] 4.061581 4.377834 4.173427
#> [2,] 4.414522 4.336272 4.194591
#> [3,] 4.405331 4.477330 4.304527
#> [4,] 4.271140 4.568010 4.140506
#> [5,] 4.477941 4.683879 5.328042
#> [6,] 3.988971 4.444584 3.874192
#> [7,] 4.477941 4.442065 4.683715
#> [8,] 4.744485 4.531486 4.370958
#> [9,] 4.123162 4.110831 4.074074
#> [10,] 4.239890 4.460957 4.262199
#> [11,] 4.443015 4.139798 4.469136
#> [12,] 4.387868 4.374055 4.192240
#> [13,] 4.036765 4.282116 3.981188
#> [14,] 4.263787 4.579345 4.592593
#> [15,] 4.053309 3.836272 3.995885
#> [16,] 4.221507 3.935768 4.292769
#> CTTAACTTCCTAGGGC-r17 CTTACCGAGGGTATCG-r17 CTTAGGAAGGAGCGTT-r17
#> [1,] 4.178497 4.360349 4.154639
#> [2,] 4.276671 3.959315 4.274055
#> [3,] 4.158572 3.900872 3.927835
#> [4,] 4.065172 4.170488 4.189863
#> [5,] 5.226027 5.380691 5.218213
#> [6,] 4.123288 3.983532 4.082474
#> [7,] 4.982565 4.863093 4.496564
#> [8,] 4.581569 4.159186 4.634021
#> [9,] 4.123910 3.949952 4.243127
#> [10,] 4.147364 4.016790 4.695876
#> [11,] 4.221254 4.038424 4.109107
#> [12,] 4.069323 4.033258 4.804124
#> [13,] 4.072229 4.051017 4.367698
#> [14,] 4.349730 4.251857 4.128007
#> [15,] 3.895600 4.040362 4.829038
#> [16,] 4.090286 4.040362 4.685567
#> CTTAGGATCCTTGCCA-r17 CTTAGGATCGCGGATC-r17 CTTGGCTTCAACTCTT-r17
#> [1,] 4.522092 4.068798 4.226044
#> [2,] 3.816952 4.402132 3.974201
#> [3,] 4.066727 4.355620 4.234644
#> [4,] 3.950406 4.325581 4.141278
#> [5,] 4.840397 4.670543 4.767813
#> [6,] 4.266907 4.438953 4.171990
#> [7,] 4.556357 4.470930 4.658477
#> [8,] 4.968440 4.408915 4.697789
#> [9,] 4.480613 4.346899 4.407862
#> [10,] 4.424707 4.567829 4.574939
#> [11,] 4.269612 4.261628 4.411548
#> [12,] 4.452660 4.169574 4.813268
#> [13,] 4.486925 4.442829 4.527027
#> [14,] 4.318305 4.242248 4.361179
#> [15,] 4.219116 3.850775 4.248157
#> [16,] 4.302976 4.868217 4.765356
#> CTTTGCGTCAGTTAGC-r17 GAAACTCAGGTGGGTT-r17 GAAATGAAGGGTTTCT-r17
#> [1,] 4.193918 4.272991 4.243206
#> [2,] 4.079755 4.257502 4.221534
#> [3,] 4.128834 4.360116 4.224974
#> [4,] 4.167778 4.401742 4.186447
#> [5,] 5.132035 4.492740 5.076367
#> [6,] 4.179515 4.188771 4.293086
#> [7,] 4.885569 4.568248 4.342621
#> [8,] 4.327821 4.591481 4.615755
#> [9,] 4.344625 4.438529 4.367045
#> [10,] 4.086690 4.480155 4.566907
#> [11,] 4.238197 4.367861 4.395597
#> [12,] 3.991198 4.330106 4.395941
#> [13,] 4.387837 4.538238 3.854145
#> [14,] 4.520405 3.911907 4.322325
#> [15,] 3.886903 4.004840 4.137599
#> [16,] 4.142971 4.605034 4.566563
#> GAAATGACATAGACTC-r17 GAAGCAGCACGTGAGA-r17 GACACGCGTAGAAGGA-r17
#> [1,] 4.869078 4.261185 4.150000
#> [2,] 3.694855 4.592503 4.267797
#> [3,] 4.193072 4.484885 4.169492
#> [4,] 4.321956 4.366385 3.936441
#> [5,] 4.789608 4.933495 4.965254
#> [6,] 3.853795 4.279323 4.159322
#> [7,] 4.723892 4.440145 4.413559
#> [8,] 4.440652 4.709794 4.684746
#> [9,] 4.111055 4.402660 4.368644
#> [10,] 4.059093 4.564692 4.405085
#> [11,] 4.164544 4.409915 4.248305
#> [12,] 4.357616 4.187424 4.114407
#> [13,] 4.251656 4.258767 4.398305
#> [14,] 4.205298 4.365175 3.922881
#> [15,] 3.925624 4.071342 4.043220
#> [16,] 4.043301 4.671100 4.727966
#> GACAGAGGTGCGCTTG-r17 GACCAATTCACTGGGC-r17 GACGCGTCATTAGCCA-r17
#> [1,] 4.270110 4.405999 4.618443
#> [2,] 4.350282 4.081931 4.228426
#> [3,] 4.323648 3.972202 4.093909
#> [4,] 4.128598 4.245062 4.181049
#> [5,] 4.771052 4.837601 4.973773
#> [6,] 4.361851 4.326993 4.433164
#> [7,] 4.385795 4.552304 4.369712
#> [8,] 4.872747 4.514996 4.746193
#> [9,] 4.145547 4.246525 4.407783
#> [10,] 4.371805 4.283102 4.390863
#> [11,] 4.728545 4.081200 4.043147
#> [12,] 4.324455 4.242136 4.396785
#> [13,] 4.337638 4.369422 4.318105
#> [14,] 4.442561 4.367959 4.027919
#> [15,] 4.195857 4.119971 3.956853
#> [16,] 4.269841 4.671544 4.191201
#> GACGTGCCACATTTCT-r17 GACGTTACATTCGACA-r17 GACGTTAGTCTGATTG-r17
#> [1,] 4.180895 4.167753 4.631373
#> [2,] 4.194727 4.183462 3.952941
#> [3,] 4.216123 4.097214 4.571242
#> [4,] 4.238383 4.226141 4.198693
#> [5,] 5.027448 4.946354 4.807843
#> [6,] 4.081694 4.070539 3.998693
#> [7,] 4.866220 4.828097 4.292810
#> [8,] 4.463799 4.504446 4.967320
#> [9,] 4.199481 4.116479 4.383007
#> [10,] 3.954182 4.154120 4.699346
#> [11,] 4.281824 4.296977 4.347712
#> [12,] 4.060514 3.892413 4.946405
#> [13,] 4.251351 4.082988 4.636601
#> [14,] 4.580290 4.503853 4.274510
#> [15,] 3.855630 4.013930 4.424837
#> [16,] 4.066350 4.201541 4.443137
#> GACTAACCAAGCTGGA-r17 GACTAACGTTCGGGCT-r17 GACTACAAGCCACCTG-r17
#> [1,] 4.183504 4.195192 4.077348
#> [2,] 4.024958 4.438462 4.335635
#> [3,] 3.966484 4.427885 4.601519
#> [4,] 4.223199 4.223077 4.281077
#> [5,] 5.203946 4.689423 4.534530
#> [6,] 4.089375 4.220192 4.216160
#> [7,] 5.014737 3.992308 4.192680
#> [8,] 4.491799 4.950962 4.606354
#> [9,] 4.005942 4.244231 5.018646
#> [10,] 4.230093 4.693269 5.089779
#> [11,] 4.078678 4.170192 4.040746
#> [12,] 3.884954 4.412500 4.470304
#> [13,] 4.161635 4.268269 4.274171
#> [14,] 4.650107 4.099038 4.325276
#> [15,] 3.898740 4.150000 4.843923
#> [16,] 4.149750 4.339423 4.126381
#> GACTACATCAATAAGG-r17 GAGGTGAGTCATATCG-r17 GAGTCCGAGACAGAGA-r17
#> [1,] 4.463145 4.194533 4.171194
#> [2,] 3.906634 4.296249 4.144478
#> [3,] 4.399263 4.019072 4.162985
#> [4,] 4.287469 4.164018 4.311642
#> [5,] 4.785012 4.878576 4.908955
#> [6,] 4.276413 4.410045 4.051343
#> [7,] 4.541769 4.760331 4.774925
#> [8,] 4.535627 4.582327 4.534478
#> [9,] 4.294840 4.282899 4.194328
#> [10,] 3.863636 4.415130 4.206567
#> [11,] 4.773956 4.098538 4.393731
#> [12,] 4.121622 4.474889 4.235970
#> [13,] 4.092138 4.143675 4.227164
#> [14,] 4.228501 3.863318 4.336119
#> [15,] 4.479115 4.188811 3.999104
#> [16,] 4.336609 4.385887 4.359403
#> GATCAGTTCAACGGCC-r17 GATCGCGAGTGCTGCC-r17 GATCGCGTCAGCCTAA-r17
#> [1,] 4.438762 4.260107 4.441573
#> [2,] 4.559892 4.129418 4.378652
#> [3,] 4.475101 4.142131 4.698876
#> [4,] 4.254374 4.160692 4.455056
#> [5,] 4.951548 5.150013 4.531461
#> [6,] 4.290713 4.170353 4.446067
#> [7,] 4.429341 4.825578 4.131461
#> [8,] 4.690444 4.632087 4.601124
#> [9,] 4.086137 4.121536 4.537079
#> [10,] 4.168237 4.241292 4.204494
#> [11,] 3.830417 4.050089 4.237079
#> [12,] 4.621803 4.109840 4.511236
#> [13,] 4.419919 4.083143 4.488764
#> [14,] 4.176312 4.408594 4.230337
#> [15,] 4.106326 3.951182 4.467416
#> [16,] 4.135935 4.053140 5.164045
#> GATCGTAAGCGTAGTG-r17 GATCGTAAGGACACCA-r17 GATGAAAGTAAATGTG-r17
#> [1,] 4.547059 4.402930 4.243167
#> [2,] 3.723529 3.934676 4.206409
#> [3,] 3.959412 4.249084 4.449890
#> [4,] 4.294118 4.501832 4.320452
#> [5,] 5.400588 5.127595 4.590638
#> [6,] 4.073529 4.100122 4.256048
#> [7,] 5.125882 4.480464 4.328621
#> [8,] 4.400588 4.462149 4.684574
#> [9,] 4.152353 4.164835 4.174364
#> [10,] 3.897059 4.282662 4.184417
#> [11,] 4.084118 4.172772 4.299717
#> [12,] 4.098824 4.235043 4.312598
#> [13,] 4.192353 4.285714 4.176249
#> [14,] 4.502353 4.384005 4.233428
#> [15,] 3.851176 4.048230 4.222746
#> [16,] 4.054118 4.042735 4.095507
#> GATGAAAGTCACTTCC-r17 GATGAAAGTGCGATAG-r17 GATGAGGTCGGTGTCG-r17
#> [1,] 4.140927 4.232997 4.296309
#> [2,] 4.207851 4.022670 3.860658
#> [3,] 4.499035 4.355793 4.197539
#> [4,] 4.368726 4.229219 4.280678
#> [5,] 4.930180 4.987406 5.395078
#> [6,] 4.118726 4.038413 4.190888
#> [7,] 4.927928 4.776448 5.068174
#> [8,] 4.653153 4.519521 4.358829
#> [9,] 4.277349 4.492443 4.131028
#> [10,] 4.261905 4.076826 4.189225
#> [11,] 4.344273 4.326196 4.214500
#> [12,] 4.275740 4.162469 4.054539
#> [13,] 4.284106 4.319899 4.047223
#> [14,] 4.398327 4.360831 4.382441
#> [15,] 4.199807 4.044081 3.977386
#> [16,] 4.162484 4.091940 4.183572
#> GATTCAGTCATGTAGC-r17 GCACATACATCCCATC-r17 GCACTCTCACCTCGTT-r17
#> [1,] 4.459612 4.350901 4.316087
#> [2,] 4.189822 4.004003 4.212072
#> [3,] 4.205170 4.261841 4.136351
#> [4,] 4.054120 4.334556 4.386958
#> [5,] 4.716478 5.263509 4.901644
#> [6,] 4.089661 4.112408 3.986796
#> [7,] 4.796446 4.777518 4.704931
#> [8,] 4.492730 4.475317 4.837241
#> [9,] 3.846527 4.242161 4.295877
#> [10,] 4.016155 4.012342 4.174347
#> [11,] 4.277060 4.194129 4.254109
#> [12,] 4.292407 4.266177 3.961196
#> [13,] 4.244750 4.104069 4.140124
#> [14,] 4.344911 4.296197 4.445971
#> [15,] 4.073506 4.255837 3.922932
#> [16,] 4.368336 4.228486 3.986527
#> GCAGCCAAGAATTGTG-r17 GCAGCCAAGGGAGTAA-r17 GCAGCCAGTACATGTC-r17
#> [1,] 4.299871 4.436255 4.499536
#> [2,] 4.108108 4.215936 3.850649
#> [3,] 4.297297 4.032669 4.466605
#> [4,] 4.048906 4.058167 4.122913
#> [5,] 4.976190 4.534263 5.100649
#> [6,] 4.922136 4.319124 4.612245
#> [7,] 4.460746 4.305578 4.383581
#> [8,] 4.869369 4.805976 4.762523
#> [9,] 4.660875 4.352988 4.715213
#> [10,] 4.433076 4.130677 4.640538
#> [11,] 4.583012 4.312749 4.497217
#> [12,] 4.368082 4.196414 4.431354
#> [13,] 3.920849 4.376892 4.079314
#> [14,] 4.339125 4.148207 4.350186
#> [15,] 4.305663 4.086056 4.121521
#> [16,] 4.538610 4.361753 4.455009
#> GCATGATGTGCTGTAT-r17 GCATGTAAGTGGGCTA-r17 GCCTCTATCGCGCCAA-r17
#> [1,] 4.427341 4.459375 4.438772
#> [2,] 3.953043 3.783125 4.278108
#> [3,] 4.118366 4.076563 4.285938
#> [4,] 4.072242 4.103438 4.286564
#> [5,] 5.182273 5.080000 4.793298
#> [6,] 4.070019 4.056563 4.165049
#> [7,] 4.911642 4.745938 4.460695
#> [8,] 4.135315 4.310313 4.799875
#> [9,] 4.067797 4.033750 4.258378
#> [10,] 3.976938 3.954063 4.214532
#> [11,] 4.304529 4.233438 4.269339
#> [12,] 4.243679 3.981875 4.315377
#> [13,] 4.225618 4.363438 4.103038
#> [14,] 4.310920 4.321875 4.317256
#> [15,] 3.927758 4.001563 4.326026
#> [16,] 4.071131 3.966563 4.498904
#> GCGCAACAGAATGTGT-r17 GCGCGATGTAACGCGA-r17 GCGCGATGTGTGGTTT-r17
#> [1,] 4.254836 4.397099 3.908012
#> [2,] 4.195963 3.994560 4.235410
#> [3,] 4.365013 4.401632 4.654797
#> [4,] 4.195122 4.302811 4.000000
#> [5,] 4.671152 4.738894 4.710188
#> [6,] 3.993272 4.048051 3.928783
#> [7,] 4.393608 4.553944 4.620178
#> [8,] 4.682086 4.515866 4.774481
#> [9,] 4.506308 4.078876 4.345203
#> [10,] 4.396131 3.912058 4.287834
#> [11,] 4.275862 4.446056 4.472799
#> [12,] 4.619008 3.862194 4.183976
#> [13,] 4.063919 4.328196 4.168150
#> [14,] 4.084104 4.519492 4.337290
#> [15,] 4.111859 4.087942 4.102868
#> [16,] 4.328007 4.257480 4.777448
#> GCGGGTTAGCGACGTA-r17 GCGGGTTCATGTAAGA-r17 GCGGGTTTCAACGGCC-r17
#> [1,] 4.305372 4.367665 4.347548
#> [2,] 3.910964 4.068263 4.433902
#> [3,] 3.986755 3.889820 4.389126
#> [4,] 4.154525 4.143713 4.309168
#> [5,] 5.217071 4.988024 4.659915
#> [6,] 4.047829 3.541317 4.604478
#> [7,] 4.680648 4.656287 4.275053
#> [8,] 4.257542 4.906587 4.704691
#> [9,] 4.004415 4.128144 4.570362
#> [10,] 4.342163 4.092216 4.438166
#> [11,] 4.338484 4.462275 4.752665
#> [12,] 3.977925 3.679042 4.634328
#> [13,] 4.297277 4.057485 4.533049
#> [14,] 4.293598 4.752096 4.332623
#> [15,] 4.019132 3.560479 4.226013
#> [16,] 4.129507 4.237126 4.174840
#> GCTCCTAAGTTAACGA-r17 GCTCCTAGTAAATGAC-r17 GCTCTGTAGAAGGTTT-r17
#> [1,] 4.232196 4.323324 4.277404
#> [2,] 4.208522 3.994102 3.916412
#> [3,] 4.353521 4.096247 4.162890
#> [4,] 4.339515 4.465416 4.196265
#> [5,] 5.110278 5.020912 5.073178
#> [6,] 4.144604 4.038338 4.116656
#> [7,] 4.737029 4.775603 4.980098
#> [8,] 4.564806 4.520912 4.338947
#> [9,] 4.241270 4.313673 4.185242
#> [10,] 4.121326 4.190885 4.071953
#> [11,] 4.202407 4.262735 4.230251
#> [12,] 4.064312 3.950402 4.208206
#> [13,] 4.172421 4.120107 4.264850
#> [14,] 4.523575 4.498391 4.330374
#> [15,] 4.074374 4.002949 4.041335
#> [16,] 4.397120 4.073727 4.347214
#> GCTGCGATCGGAATCT-r17 GCTTGAATCTCTAAGG-r17 GGAACTTGTTAAAGTG-r17
#> [1,] 4.443038 4.305057 4.689076
#> [2,] 4.073515 4.238173 4.306723
#> [3,] 4.368062 4.149538 4.436975
#> [4,] 4.316943 4.244698 4.355042
#> [5,] 4.818890 4.452420 4.566176
#> [6,] 4.042843 4.224035 4.558824
#> [7,] 4.822785 4.414899 4.593487
#> [8,] 4.633398 4.677542 4.809874
#> [9,] 4.259494 4.339859 4.644958
#> [10,] 4.286758 4.325177 4.435924
#> [11,] 4.116845 4.296357 4.418067
#> [12,] 4.378286 4.205546 4.697479
#> [13,] 4.174294 4.249048 4.716387
#> [14,] 4.283350 4.449157 4.265756
#> [15,] 4.263389 4.135943 4.199580
#> [16,] 4.107595 4.396955 4.470588
#> GGAACTTGTTGCGTTA-r17 GGAATAAAGTATTGGA-r17 GGACAAGAGGCCCTTG-r17
#> [1,] 4.464233 4.291016 4.224701
#> [2,] 4.032817 4.027344 4.059230
#> [3,] 4.063053 4.073568 4.121647
#> [4,] 4.010693 4.214193 4.250199
#> [5,] 5.299410 5.085286 5.257636
#> [6,] 4.897861 3.977865 4.112616
#> [7,] 4.452065 4.464193 4.882869
#> [8,] 4.661136 4.468750 4.514741
#> [9,] 4.161873 4.017578 4.106773
#> [10,] 4.556785 3.898438 4.037981
#> [11,] 4.180310 4.195313 4.277291
#> [12,] 4.519174 4.098307 4.061089
#> [13,] 3.846239 4.124349 4.249137
#> [14,] 4.182522 4.345703 4.484993
#> [15,] 4.199115 4.148437 3.981142
#> [16,] 4.569690 4.583984 4.249137
#> GGACAAGCACTGTCGG-r17 GGACAGAAGCTAGTCT-r17 GGACATTCAAAGGCGT-r17
#> [1,] 3.988008 4.387468 4.439733
#> [2,] 4.371752 3.974425 4.072683
#> [3,] 4.231845 4.093990 4.256208
#> [4,] 3.943371 4.309463 4.017565
#> [5,] 4.906729 4.987212 5.127196
#> [6,] 3.770153 3.898977 4.073895
#> [7,] 4.624917 4.855499 4.496063
#> [8,] 4.658228 4.471228 4.634161
#> [9,] 4.229847 4.313939 4.313749
#> [10,] 3.904064 3.941816 4.037553
#> [11,] 4.465023 4.306905 4.459721
#> [12,] 4.001332 3.848465 4.015748
#> [13,] 4.093271 4.101662 3.986069
#> [14,] 4.769487 4.587596 4.316778
#> [15,] 3.804797 3.817136 4.235009
#> [16,] 4.253831 4.138747 4.374319
#> GGACATTCACCAACCG-r17 GGACGTCCACTGTCGG-r17 GGCAATTTCACGACTA-r17
#> [1,] 4.398356 4.405200 4.297993
#> [2,] 4.379671 4.365114 4.159547
#> [3,] 4.401345 4.457205 4.125579
#> [4,] 4.067265 4.659805 4.236747
#> [5,] 5.088939 4.721560 4.763253
#> [6,] 4.494021 4.430119 4.011323
#> [7,] 4.458146 4.346696 4.830160
#> [8,] 4.509716 4.611051 4.561503
#> [9,] 4.494768 4.654388 4.278435
#> [10,] 4.625561 4.328277 4.150798
#> [11,] 4.286996 4.620802 4.388060
#> [12,] 4.303438 4.685807 4.276377
#> [13,] 4.148729 3.958830 4.072568
#> [14,] 4.265321 4.271939 4.219249
#> [15,] 4.196562 4.404117 3.946989
#> [16,] 4.703288 4.035753 4.078230
#> GGCGACTAGCCAGTTT-r17 GGCGACTGTTCAGACT-r17 GGCTGGTAGGATGGTC-r17
#> [1,] 4.336842 4.530441 4.344322
#> [2,] 4.182775 3.636986 4.002616
#> [3,] 4.287081 3.837139 4.203035
#> [4,] 3.979904 4.091324 4.495552
#> [5,] 5.435407 5.302131 5.006279
#> [6,] 4.371292 4.033486 3.721088
#> [7,] 4.613397 4.676560 4.791209
#> [8,] 5.101435 4.630137 4.476190
#> [9,] 4.772249 4.003805 4.018315
#> [10,] 4.369378 4.122527 4.150706
#> [11,] 4.345455 4.162861 4.462585
#> [12,] 4.379904 4.187976 4.341183
#> [13,] 3.935885 4.263318 4.142334
#> [14,] 4.165550 4.416286 4.581894
#> [15,] 4.046890 4.047945 3.819990
#> [16,] 4.889952 4.152207 4.219257
#> GGGAATGAGCCGGTAA-r17 GGGACCTTCCTGCTTG-r17 GGGATGATCTTCATGT-r17
#> [1,] 4.019663 4.273354 4.348247
#> [2,] 4.365169 4.042633 4.015719
#> [3,] 4.220506 3.640752 3.967352
#> [4,] 4.050562 3.964263 3.771463
#> [5,] 4.390449 5.161129 5.103990
#> [6,] 3.867978 3.831348 4.492140
#> [7,] 4.160112 5.030721 4.292624
#> [8,] 5.099719 4.709718 4.925030
#> [9,] 4.608146 4.169279 4.475212
#> [10,] 4.328652 3.692790 4.440145
#> [11,] 4.633427 4.085893 4.082225
#> [12,] 4.640449 3.802508 4.596131
#> [13,] 4.112360 3.983072 4.200726
#> [14,] 4.081461 4.774295 4.163241
#> [15,] 4.212079 3.682759 4.199516
#> [16,] 4.633427 3.740439 4.461911
#> GGGCACTAGCTATGCT-r17 GGGCACTTCGGTCTAA-r17 GGGTCTGGTTGAGTTC-r17
#> [1,] 4.064439 4.390159 4.407376
#> [2,] 4.389021 4.045911 4.066130
#> [3,] 4.116150 4.170998 4.140738
#> [4,] 4.060461 4.355856 4.458669
#> [5,] 4.682578 4.902460 5.202628
#> [6,] 4.008751 3.962751 4.111488
#> [7,] 4.303103 4.564969 4.799915
#> [8,] 4.924423 4.459113 4.636287
#> [9,] 4.308671 4.222453 4.267486
#> [10,] 4.429594 4.142931 4.032217
#> [11,] 4.283214 4.360707 4.153031
#> [12,] 4.141607 4.284477 3.982196
#> [13,] 4.270485 4.115731 4.121662
#> [14,] 4.355609 4.297124 4.474777
#> [15,] 4.174224 4.049550 4.025011
#> [16,] 4.369133 4.279626 4.112336
#> GGGTTGCAGCGTAGTG-r17 GGTATTGTCCTCCTAG-r17 GGTATTGTCTCGCTTG-r17
#> [1,] 4.388054 4.349021 4.273636
#> [2,] 4.383044 3.836597 4.267487
#> [3,] 4.908671 4.042678 4.513451
#> [4,] 4.396917 4.283835 4.139124
#> [5,] 4.543738 5.018708 4.946964
#> [6,] 4.322929 3.774920 4.652575
#> [7,] 4.488632 4.831920 4.447348
#> [8,] 4.598073 4.273020 4.837817
#> [9,] 4.147592 4.066063 4.527287
#> [10,] 4.501349 3.989769 4.371253
#> [11,] 4.300578 4.172172 4.323597
#> [12,] 4.573025 3.944168 4.544197
#> [13,] 4.275145 4.187664 4.205227
#> [14,] 4.267823 4.468576 4.209839
#> [15,] 4.220809 3.913476 4.279016
#> [16,] 4.326782 4.037416 4.534973
#> GGTGAAGAGCTAGTCT-r17 GGTGCGTCAATCTGCA-r17 GTAACGTAGCAAATCA-r17
#> [1,] 4.428335 4.447684 4.303201
#> [2,] 4.338028 4.157233 3.858131
#> [3,] 4.095278 4.077759 4.068772
#> [4,] 3.932063 4.116066 4.407872
#> [5,] 4.833471 4.716409 5.243512
#> [6,] 4.366197 4.126930 4.057526
#> [7,] 4.311516 4.151515 4.902682
#> [8,] 4.714996 4.928531 4.588668
#> [9,] 4.425021 4.393939 4.232266
#> [10,] 4.278376 4.339051 4.031142
#> [11,] 3.959403 4.275586 4.152682
#> [12,] 4.364540 4.256718 3.881920
#> [13,] 4.327258 4.519154 4.138408
#> [14,] 4.260149 4.308176 4.492647
#> [15,] 4.251864 3.848485 3.996540
#> [16,] 4.620547 4.432819 4.021194
#> GTACGTATCGAGGTAG-r17 GTACGTATCGCATGGC-r17 GTACTCCGTTCCAACA-r17
#> [1,] 4.325210 4.300000 4.365269
#> [2,] 4.145054 4.360204 4.128144
#> [3,] 4.295909 4.336735 4.573653
#> [4,] 4.238468 4.265306 4.501796
#> [5,] 5.006382 4.573469 4.779641
#> [6,] 4.071657 4.416327 4.294611
#> [7,] 4.740354 4.296939 4.023952
#> [8,] 4.620830 4.590816 4.735329
#> [9,] 4.290688 4.398980 4.336527
#> [10,] 4.234987 4.330612 4.427545
#> [11,] 4.145924 4.372449 4.222754
#> [12,] 4.299971 4.211224 4.344910
#> [13,] 4.292718 4.306122 4.311377
#> [14,] 4.323180 4.208163 4.015569
#> [15,] 4.229475 4.113265 4.146108
#> [16,] 4.372788 4.326531 4.600000
#> GTACTCCTCGAATGCT-r17 GTACTTTCACATCCAA-r17 GTACTTTGTAAGGGCT-r17
#> [1,] 4.384089 4.259385 4.199813
#> [2,] 4.632164 3.767332 4.307190
#> [3,] 4.145423 4.121745 4.088702
#> [4,] 4.131737 4.181941 4.309057
#> [5,] 4.455945 5.147109 4.805789
#> [6,] 3.902481 4.021982 4.194211
#> [7,] 4.425150 5.028407 4.521008
#> [8,] 4.619333 4.269192 4.379085
#> [9,] 4.634731 3.887048 4.290383
#> [10,] 4.197605 4.105174 4.393091
#> [11,] 4.319932 4.182618 4.312792
#> [12,] 4.466210 4.055123 4.575163
#> [13,] 4.447391 4.312141 4.073763
#> [14,] 4.013687 4.429489 4.305322
#> [15,] 4.199316 3.745012 3.848739
#> [16,] 4.619333 4.053433 4.725490
#> GTAGGCCCACCGATAT-r17 GTAGTCACAGGAATCG-r17 GTATCTTAGCAAATCA-r17
#> [1,] 4.267896 4.183463 4.386776
#> [2,] 4.191974 4.250646 3.824166
#> [3,] 4.259219 4.351421 4.014628
#> [4,] 4.406725 4.019380 4.007607
#> [5,] 4.434924 4.525840 5.370685
#> [6,] 4.191974 4.040052 4.120246
#> [7,] 4.364425 4.285530 5.121123
#> [8,] 4.818872 4.905685 4.153891
#> [9,] 4.670282 4.412145 3.970158
#> [10,] 4.183297 4.299742 4.052662
#> [11,] 4.241866 4.179587 4.212405
#> [12,] 4.364425 4.242894 4.311293
#> [13,] 4.607375 4.304910 4.110591
#> [14,] 4.265727 4.229974 4.193681
#> [15,] 4.160521 4.103359 3.937975
#> [16,] 4.504338 4.717054 4.077531
#> GTATTCTCAATAGCGG-r17 GTATTCTCACTCAGGC-r17 GTCACAACACCTATCC-r17
#> [1,] 4.088723 4.399038 4.223459
#> [2,] 4.734660 4.330357 4.310788
#> [3,] 4.226368 4.281593 4.359589
#> [4,] 3.929519 4.105769 4.312500
#> [5,] 4.738806 4.649725 4.798801
#> [6,] 3.676617 4.047390 3.755993
#> [7,] 4.523217 4.666896 4.578767
#> [8,] 4.828358 4.609203 4.788527
#> [9,] 4.218076 4.184753 3.875000
#> [10,] 4.151741 4.491071 4.015411
#> [11,] 4.289386 4.453984 4.177226
#> [12,] 3.898010 4.685440 3.941781
#> [13,] 3.982587 4.612637 4.301370
#> [14,] 4.851575 4.078297 4.274829
#> [15,] 3.912935 4.517170 3.831336
#> [16,] 4.025705 4.434753 4.313356
#> GTCATTTAGGCAATTA-r17 GTCATTTCATTCGACA-r17 GTCATTTTCCTCAATT-r17
#> [1,] 4.188008 4.281034 4.565794
#> [2,] 4.344512 4.034483 4.269812
#> [3,] 4.175813 3.968276 3.873572
#> [4,] 4.186992 4.330690 4.221157
#> [5,] 4.804878 5.226897 4.923332
#> [6,] 4.394309 4.125172 4.302248
#> [7,] 4.485772 5.035517 4.603022
#> [8,] 4.612805 4.556552 4.793586
#> [9,] 4.164634 4.171034 4.335053
#> [10,] 4.481707 3.954483 4.246959
#> [11,] 4.231707 4.291379 4.241430
#> [12,] 4.409553 3.951724 4.250276
#> [13,] 4.324187 4.142759 4.298194
#> [14,] 3.830285 4.517241 4.161813
#> [15,] 3.803862 3.953448 4.195724
#> [16,] 4.921748 4.210345 4.368227
#> GTCTCGTCAAGCTGAG-r17 GTCTTCGCACTTCGAA-r17 GTGAAGGAGCTAAGAT-r17
#> [1,] 3.937166 4.188011 4.364903
#> [2,] 4.645722 3.896458 3.839678
#> [3,] 4.029412 4.135634 3.892293
#> [4,] 4.114973 4.351801 4.571959
#> [5,] 5.032086 5.247956 5.209842
#> [6,] 4.274064 4.158946 4.109564
#> [7,] 4.278743 4.926431 5.010523
#> [8,] 4.707219 4.254617 4.404519
#> [9,] 4.141043 3.948229 4.018880
#> [10,] 4.524064 4.116258 4.027546
#> [11,] 3.910428 4.157735 4.124729
#> [12,] 4.563503 4.063276 4.064995
#> [13,] 4.080214 4.228277 4.131538
#> [14,] 4.009358 4.287617 4.280099
#> [15,] 4.182487 4.006358 3.957908
#> [16,] 4.086898 4.214956 3.896626
#> GTGAAGGAGGGCTTCC-r17 GTGAAGGCAGCTGCTG-r17 GTGCAGCCATCTCGCT-r17
#> [1,] 4.250642 4.215628 4.465188
#> [2,] 3.967494 4.147379 4.467251
#> [3,] 4.020816 4.335312 4.143889
#> [4,] 4.236955 4.086053 4.118102
#> [5,] 5.176219 5.059347 5.145952
#> [6,] 4.227830 4.090010 4.392470
#> [7,] 4.903336 4.720079 4.648788
#> [8,] 4.672084 4.634026 4.793708
#> [9,] 4.025663 4.093966 4.447653
#> [10,] 4.158825 4.135509 4.279526
#> [11,] 4.311092 4.171118 4.277463
#> [12,] 4.203308 4.200791 4.579165
#> [13,] 4.146279 3.875371 4.173285
#> [14,] 4.224693 4.251236 4.098504
#> [15,] 3.995723 4.050445 4.273337
#> [16,] 4.361277 4.038576 4.531202
#> GTGCAGCGTGCAACTT-r17 GTGCATAAGGAACTGC-r17 GTGCGGTCATGACATC-r17
#> [1,] 4.095563 4.514768 4.162284
#> [2,] 4.004096 4.315401 4.079538
#> [3,] 4.165870 4.459916 3.915972
#> [4,] 4.114676 4.295359 4.084990
#> [5,] 4.649829 4.488397 5.108403
#> [6,] 4.058703 4.459916 3.978512
#> [7,] 4.691468 3.949367 5.077293
#> [8,] 4.402048 4.890295 4.687300
#> [9,] 4.407509 4.495781 4.133098
#> [10,] 4.321502 4.546414 4.157793
#> [11,] 4.165188 4.220464 4.112572
#> [12,] 4.375427 4.392405 4.096857
#> [13,] 4.378157 4.517932 4.090763
#> [14,] 4.070990 4.149789 4.442912
#> [15,] 4.031399 4.459916 3.817832
#> [16,] 4.290102 4.317511 3.841886
#> GTGCTTCCAGCTGCTG-r17 GTGCTTCCAGGTCGTC-r17 GTGCTTCGTTCCACGG-r17
#> [1,] 4.312624 4.155005 4.378849
#> [2,] 4.162591 4.424112 3.942436
#> [3,] 3.853933 4.228202 4.161312
#> [4,] 3.816920 4.066738 4.211513
#> [5,] 5.121613 4.625404 4.981258
#> [6,] 3.762062 4.009150 4.032463
#> [7,] 4.474554 4.064047 4.978916
#> [8,] 4.690681 4.954252 4.450469
#> [9,] 4.385988 4.103875 3.869813
#> [10,] 4.192333 4.295479 4.072289
#> [11,] 4.348315 4.217976 4.253681
#> [12,] 4.061467 4.163617 4.268742
#> [13,] 4.194316 4.149085 4.229920
#> [14,] 4.839392 4.323466 4.202142
#> [15,] 3.877065 4.293326 3.966198
#> [16,] 4.059484 4.224973 3.923025
#> GTGGGTCAGATGCCAG-r17 GTGGGTCTCGTGACAT-r17 GTGTTAGAGAACTCGG-r17
#> [1,] 4.086674 4.141618 4.052925
#> [2,] 4.340195 4.522399 4.230269
#> [3,] 4.371614 4.373555 4.419684
#> [4,] 4.186349 4.250000 4.525534
#> [5,] 4.563380 4.693642 4.403900
#> [6,] 3.855905 4.356936 4.293408
#> [7,] 4.420368 4.255058 4.089136
#> [8,] 4.841820 4.669798 4.772516
#> [9,] 4.170098 4.379335 4.544104
#> [10,] 4.110509 4.846098 4.275766
#> [11,] 4.624052 4.345376 4.387187
#> [12,] 4.405200 4.620665 4.280409
#> [13,] 4.205850 4.387283 4.427112
#> [14,] 4.503792 4.296965 4.771588
#> [15,] 4.202600 4.930636 4.103993
#> [16,] 4.210184 4.171243 3.837512
#> GTTAAGCAGAAACGCC-r17 GTTAAGCAGAGTTGGC-r17 GTTACAGAGGGTGTGT-r17
#> [1,] 4.269827 3.947669 4.441116
#> [2,] 4.271650 3.980971 4.154959
#> [3,] 4.383774 4.306375 4.127066
#> [4,] 4.375570 3.942912 4.262397
#> [5,] 4.618049 4.485252 5.066116
#> [6,] 4.217867 4.001903 3.909091
#> [7,] 4.147675 4.561370 4.674587
#> [8,] 4.627165 4.960990 4.521694
#> [9,] 4.410210 4.737393 4.232438
#> [10,] 4.500456 4.489058 4.140496
#> [11,] 4.371923 4.458611 4.071281
#> [12,] 4.474932 4.588011 4.060950
#> [13,] 4.497721 4.378687 4.293388
#> [14,] 4.314494 4.393911 4.301653
#> [15,] 3.985415 3.978116 4.175620
#> [16,] 4.478578 4.664129 4.183884
#> GTTACAGAGTCGTACT-r17 GTTACAGGTTGGAGGT-r17 GTTCATTAGCACCGTC-r17
#> [1,] 3.963636 4.244009 4.328335
#> [2,] 4.286364 4.106996 4.104183
#> [3,] 4.231061 4.209392 3.960537
#> [4,] 4.176515 4.261922 3.892660
#> [5,] 4.621970 5.305011 4.932123
#> [6,] 4.133333 4.210119 3.571429
#> [7,] 4.627273 4.933430 4.717443
#> [8,] 4.886364 4.532559 4.512234
#> [9,] 4.333333 4.110143 4.345699
#> [10,] 4.809091 4.300412 3.638516
#> [11,] 4.213636 4.229726 4.338595
#> [12,] 4.323485 4.184217 3.907656
#> [13,] 4.285606 4.296780 4.300710
#> [14,] 4.314394 4.299201 4.682715
#> [15,] 4.097727 4.014282 3.801105
#> [16,] 4.609091 4.145727 3.810576
#> GTTCGGGTCACTGGGC-r17 GTTCTCGAGAGAACAG-r17 TAAACCGAGAACAATC-r17
#> [1,] 4.495407 4.378476 4.548252
#> [2,] 4.099738 4.420798 4.346853
#> [3,] 4.261811 4.333736 4.006993
#> [4,] 4.150919 4.073761 3.993007
#> [5,] 4.645669 5.016929 4.423776
#> [6,] 4.341207 4.296252 4.426573
#> [7,] 4.382546 4.507860 4.433566
#> [8,] 4.774278 4.779927 4.759441
#> [9,] 4.459974 4.900846 4.332867
#> [10,] 4.326772 3.927449 4.345455
#> [11,] 4.084646 4.541717 4.662937
#> [12,] 4.250000 4.860943 4.386014
#> [13,] 4.503281 4.529625 4.613986
#> [14,] 4.193570 4.418380 4.172028
#> [15,] 4.095144 4.216445 4.380420
#> [16,] 4.309055 4.674728 4.418182
#> TAAGAGAAGACTGTAA-r17 TAAGAGAAGGCCGAAT-r17 TACAGTGTCAAACCAC-r17
#> [1,] 4.290526 4.295800 4.417823
#> [2,] 4.159270 4.376229 3.844184
#> [3,] 4.291155 4.496872 4.104055
#> [4,] 4.257476 4.241287 4.402348
#> [5,] 5.065156 4.684540 5.009605
#> [6,] 4.135348 3.754245 4.026681
#> [7,] 4.681775 4.529044 4.654749
#> [8,] 4.436575 4.482574 4.436499
#> [9,] 4.172175 3.958892 4.232657
#> [10,] 4.134404 4.208222 3.932231
#> [11,] 4.375826 4.375335 4.390608
#> [12,] 4.099150 4.026810 4.161686
#> [13,] 4.339629 4.307417 4.337780
#> [14,] 4.331130 4.537980 4.495197
#> [15,] 4.271325 4.115282 3.887407
#> [16,] 4.571294 4.106345 3.862860
#> TACGGATCACGACTCG-r17 TACGGATCAGGAATCG-r17 TACGGATTCACGCATA-r17
#> [1,] 4.712981 4.266781 4.048845
#> [2,] 3.519896 4.567986 4.939609
#> [3,] 4.151990 4.324441 4.209591
#> [4,] 4.097195 4.123064 4.145648
#> [5,] 4.901500 4.460413 4.663410
#> [6,] 3.820613 4.180723 3.709591
#> [7,] 4.770385 4.281411 4.325044
#> [8,] 4.397913 4.529260 4.748668
#> [9,] 4.249185 4.487952 4.101243
#> [10,] 3.926941 4.580034 3.962700
#> [11,] 4.303979 4.243546 4.637655
#> [12,] 4.155251 4.581756 3.940497
#> [13,] 4.175473 4.327022 4.055950
#> [14,] 4.221787 4.130809 4.694494
#> [15,] 3.922374 4.352840 3.920959
#> [16,] 3.805610 4.204819 4.277975
#> TACGGATTCCTGTAGA-r17 TACGGTAGTGCCTGCA-r17 TACGGTAGTTTGTGTG-r17
#> [1,] 4.182105 4.134864 4.079219
#> [2,] 4.173684 4.428981 4.262615
#> [3,] 4.200000 4.124821 4.005155
#> [4,] 4.370526 4.200861 4.147585
#> [5,] 4.886316 4.705882 4.921053
#> [6,] 4.424211 4.265423 4.205372
#> [7,] 4.706316 4.378766 4.807922
#> [8,] 4.689474 4.895265 4.824471
#> [9,] 4.035789 4.823529 4.245795
#> [10,] 4.096842 4.120516 4.201845
#> [11,] 4.263158 4.319943 4.241725
#> [12,] 4.177895 4.322812 4.085458
#> [13,] 4.320000 4.736011 4.246609
#> [14,] 4.523158 4.025825 4.329083
#> [15,] 3.983158 4.259684 4.105263
#> [16,] 4.163158 4.265423 4.199946
#> TACGGTATCCCACTTG-r17 TACTCATGTACTTGAC-r17 TACTCATTCACATACG-r17
#> [1,] 4.362213 4.141732 4.500000
#> [2,] 4.343424 4.032928 3.764184
#> [3,] 4.155532 4.168933 3.949025
#> [4,] 4.194154 4.362205 4.253546
#> [5,] 4.635699 4.859699 4.995567
#> [6,] 4.295407 4.032928 3.873670
#> [7,] 4.381002 4.700072 4.790337
#> [8,] 4.584551 4.406586 4.349734
#> [9,] 4.648225 4.331424 4.038121
#> [10,] 4.356994 4.061560 4.036791
#> [11,] 4.484342 4.371510 4.036348
#> [12,] 4.578288 4.279885 3.983599
#> [13,] 4.498956 4.410165 4.172429
#> [14,] 4.751566 4.392269 4.273493
#> [15,] 4.141962 4.289191 3.894947
#> [16,] 4.488518 4.146743 4.218972
#> TACTCGCTCCTAGGGC-r17 TACTTACCACTATCTT-r17 TAGACCAGTACGACCC-r17
#> [1,] 4.363115 4.438942 4.188811
#> [2,] 4.292623 4.402985 4.273999
#> [3,] 4.255738 4.075984 4.492689
#> [4,] 4.562295 4.184532 4.314685
#> [5,] 5.034426 4.818860 4.376987
#> [6,] 4.115574 4.308684 4.308964
#> [7,] 4.241803 4.231343 4.348379
#> [8,] 4.805738 5.121438 4.535919
#> [9,] 4.826230 4.592944 4.195168
#> [10,] 4.236066 4.381275 4.454545
#> [11,] 4.245902 4.378562 4.361729
#> [12,] 4.245082 4.335142 4.156389
#> [13,] 4.669672 4.511533 4.169104
#> [14,] 4.074590 4.410448 4.544183
#> [15,] 3.885246 4.157395 4.170375
#> [16,] 4.381967 4.530529 4.174825
#> TAGACCATCCGGCACA-r17 TAGAGCTAGACTCGGA-r17 TAGAGCTTCTCCAGGG-r17
#> [1,] 4.344617 4.345481 4.495597
#> [2,] 4.253216 4.092930 4.347170
#> [3,] 4.172647 4.431851 4.345912
#> [4,] 4.182803 4.254373 4.539623
#> [5,] 4.907244 4.838921 4.597484
#> [6,] 4.692620 4.070335 4.393711
#> [7,] 4.441435 4.650510 4.104403
#> [8,] 4.712255 4.410714 5.130818
#> [9,] 4.395396 4.180029 4.218868
#> [10,] 4.282329 4.145044 4.563522
#> [11,] 4.159106 4.239796 4.077987
#> [12,] 4.531483 4.286808 4.389937
#> [13,] 4.339201 4.251458 4.361006
#> [14,] 4.252539 4.205539 4.206289
#> [15,] 4.306703 4.146137 4.311950
#> [16,] 4.618145 4.149052 4.323270
#> TAGCCGGGTGAGGGTT-r17 TAGGCATCAATACGCT-r17 TAGTGGTAGATGCCAG-r17
#> [1,] 4.119891 4.252172 4.531738
#> [2,] 4.216621 4.095815 3.713379
#> [3,] 4.295640 4.273230 4.262207
#> [4,] 4.303815 4.299553 4.098633
#> [5,] 4.460490 4.902606 4.882812
#> [6,] 4.103542 3.904185 4.024414
#> [7,] 4.614441 4.785207 4.797852
#> [8,] 4.859673 4.363253 4.564453
#> [9,] 4.818801 4.179784 4.267578
#> [10,] 4.510899 4.002369 3.984863
#> [11,] 4.317439 4.411951 4.375977
#> [12,] 4.066757 4.081600 4.194336
#> [13,] 4.685286 4.284812 4.289551
#> [14,] 3.979564 4.293498 4.116211
#> [15,] 3.866485 4.033693 4.131836
#> [16,] 4.346049 4.113451 4.092773
#> TAGTTGGAGTGTTTGC-r17 TATCAGGCAAGAAAGG-r17 TATCAGGCAATAAGCA-r17
#> [1,] 4.326138 4.186047 4.408910
#> [2,] 4.107935 3.733087 4.528590
#> [3,] 4.239207 3.975159 4.307181
#> [4,] 4.245333 4.245243 4.307846
#> [5,] 4.898775 4.928647 4.386303
#> [6,] 4.133897 3.813953 4.176862
#> [7,] 4.729580 5.112579 4.399601
#> [8,] 4.568553 4.387421 4.937500
#> [9,] 4.141482 4.132135 4.422872
#> [10,] 4.160735 3.912262 4.337766
#> [11,] 4.163652 4.220402 4.609043
#> [12,] 4.307468 4.258457 4.240027
#> [13,] 4.219078 3.995772 4.269282
#> [14,] 4.303676 4.391121 4.134309
#> [15,] 4.301050 3.830338 4.143617
#> [16,] 4.342474 4.267442 4.375000
#> TATCTCAAGATGTGGC-r17 TATGCCCCATCACGAT-r17 TATTACCAGTTGAGTA-r17
#> [1,] 4.145889 3.873773 4.632934
#> [2,] 4.095491 4.440393 3.793413
#> [3,] 4.137047 3.814867 4.042515
#> [4,] 4.120248 4.064516 4.257485
#> [5,] 4.965517 4.915849 5.101198
#> [6,] 4.307692 3.838710 4.105988
#> [7,] 4.535809 4.737728 4.596407
#> [8,] 4.466844 4.468443 4.234731
#> [9,] 4.377542 4.081346 4.117365
#> [10,] 4.609195 4.105189 3.874850
#> [11,] 4.088417 4.115007 4.255689
#> [12,] 4.597701 4.074334 3.983832
#> [13,] 4.180371 3.956522 4.101796
#> [14,] 4.426172 4.859748 4.451497
#> [15,] 4.385500 3.776999 4.013174
#> [16,] 4.529620 3.868163 4.070659
#> TCAACGAGTCGACTGC-r17 TCAATCTGTTACAGAA-r17 TCACAAGGTCGCATAT-r17
#> [1,] 4.382924 4.179730 4.243673
#> [2,] 4.256792 4.372297 4.236021
#> [3,] 4.164295 4.320270 4.230135
#> [4,] 4.306598 4.347297 4.251913
#> [5,] 4.644890 4.695946 4.918776
#> [6,] 4.208926 3.966892 4.284873
#> [7,] 4.499353 4.605405 4.632137
#> [8,] 4.816300 4.697297 4.772808
#> [9,] 4.589263 4.257432 4.434373
#> [10,] 4.388745 4.485811 4.480871
#> [11,] 4.535576 4.647973 4.255444
#> [12,] 4.569211 4.725676 4.346086
#> [13,] 4.320828 4.627027 4.065333
#> [14,] 4.137128 4.417568 4.178929
#> [15,] 4.452135 4.533784 4.170100
#> [16,] 4.546572 4.610811 4.488523
#> TCACGAAAGTGGCACA-r17 TCAGATGAGTTAGGTA-r17 TCAGATGTCGATAGAA-r17
#> [1,] 4.104252 4.407751 4.385640
#> [2,] 4.403292 3.975016 4.167342
#> [3,] 4.319616 3.896220 4.392588
#> [4,] 4.263374 4.332159 4.174870
#> [5,] 5.067901 5.118193 4.715692
#> [6,] 4.072016 4.111467 4.327157
#> [7,] 4.676955 4.983985 4.609728
#> [8,] 4.462963 4.588725 4.474812
#> [9,] 4.150206 3.908392 4.349739
#> [10,] 4.166667 4.078155 4.363636
#> [11,] 4.502743 4.000641 4.484655
#> [12,] 4.249657 3.899744 4.563405
#> [13,] 4.168724 4.130365 4.410539
#> [14,] 4.391632 4.309417 4.297047
#> [15,] 3.841564 3.900705 4.207296
#> [16,] 4.353909 4.140295 4.136653
#> TCAGCTCCAATTGCTG-r17 TCAGGATTCGTACCGG-r17 TCAGGTATCCTAAGTG-r17
#> [1,] 4.221777 4.680827 4.442046
#> [2,] 4.053362 4.123533 4.536371
#> [3,] 4.042566 4.047513 4.202238
#> [4,] 4.123072 3.752935 4.236611
#> [5,] 5.251080 5.242035 4.919265
#> [6,] 3.868908 4.252655 4.443645
#> [7,] 4.982110 4.542761 4.402878
#> [8,] 4.426280 4.745109 4.783373
#> [9,] 3.905614 4.279486 4.441247
#> [10,] 4.049352 4.380101 4.485212
#> [11,] 4.198951 4.145333 4.404476
#> [12,] 4.179827 4.512018 4.527578
#> [13,] 4.239050 4.428731 4.441247
#> [14,] 4.308143 4.108999 4.291767
#> [15,] 4.099013 4.092230 4.151079
#> [16,] 4.295805 4.738960 4.408473
#> TCCACACTCTTGAGAC-r17 TCCCGATAGCTAGTCT-r17 TCCCGATTCTTTACAC-r17
#> [1,] 4.171097 4.240654 4.164807
#> [2,] 4.132243 4.488318 4.099571
#> [3,] 4.070893 4.531542 3.992561
#> [4,] 4.074301 4.386682 4.233476
#> [5,] 5.073620 4.475467 5.307010
#> [6,] 4.147921 4.492991 4.134192
#> [7,] 4.896046 4.295561 4.989413
#> [8,] 4.504090 4.906542 4.338484
#> [9,] 4.237900 4.432243 4.243205
#> [10,] 4.125426 4.482477 4.164235
#> [11,] 4.298909 4.649533 3.958798
#> [12,] 3.980573 4.573598 3.988555
#> [13,] 4.117587 4.167056 4.247496
#> [14,] 4.548739 4.079439 4.412876
#> [15,] 4.021132 4.428738 3.923891
#> [16,] 4.061009 4.755841 4.191416
#> TCGGTAAAGGAGCGTT-r17 TCGGTAACAGGAATCG-r17 TCGGTAATCCATGAGT-r17
#> [1,] 4.220588 4.418550 4.296512
#> [2,] 4.072890 4.039751 4.108721
#> [3,] 3.909847 4.382697 4.083140
#> [4,] 4.085038 4.464536 4.127326
#> [5,] 5.531969 4.865160 5.286047
#> [6,] 4.160486 3.954793 3.926163
#> [7,] 4.984655 4.848012 4.921512
#> [8,] 4.470588 4.505846 4.491860
#> [9,] 4.073529 4.238504 4.131395
#> [10,] 4.078645 4.006235 4.050581
#> [11,] 4.035806 4.525331 4.219767
#> [12,] 4.235294 3.989088 4.037791
#> [13,] 3.889386 4.333593 3.797093
#> [14,] 4.144501 4.392050 4.375581
#> [15,] 3.920716 3.879189 4.028488
#> [16,] 4.247442 4.461419 4.191279
#> TCGTACCCAGACTCGC-r17 TCGTAGAAGAAGGCCT-r17 TCGTAGAAGGGTATCG-r17
#> [1,] 4.131788 4.428760 4.358056
#> [2,] 3.999682 4.187335 3.941176
#> [3,] 4.118768 4.335092 4.104348
#> [4,] 4.418228 3.976253 4.245013
#> [5,] 5.338520 4.604222 5.223529
#> [6,] 4.111782 3.852243 4.147826
#> [7,] 4.983169 4.147757 5.062916
#> [8,] 4.233090 4.691293 4.381074
#> [9,] 4.189266 4.460422 3.900256
#> [10,] 4.278501 4.274406 4.061381
#> [11,] 4.102255 4.226913 4.139642
#> [12,] 4.219117 4.126649 4.334527
#> [13,] 4.363290 4.559367 4.212276
#> [14,] 4.464274 4.331135 4.310997
#> [15,] 3.749762 4.254617 4.002558
#> [16,] 4.170848 4.106860 4.059847
#> TCTATTGCATAGACTC-r17 TCTATTGTCATCGATG-r17 TCTATTGTCATTCACT-r17
#> [1,] 4.208260 4.280205 4.329559
#> [2,] 3.948155 3.952218 3.995664
#> [3,] 4.001318 3.991468 4.235847
#> [4,] 4.248682 4.231741 4.154662
#> [5,] 5.106766 5.173720 5.086244
#> [6,] 3.894112 3.982594 4.006504
#> [7,] 5.004394 5.069625 4.765117
#> [8,] 4.518893 4.560068 4.466875
#> [9,] 4.261424 4.091809 3.997350
#> [10,] 3.855009 4.143003 4.157793
#> [11,] 3.984183 4.175427 4.200193
#> [12,] 3.963972 4.072696 4.101662
#> [13,] 4.140158 4.199659 4.193447
#> [14,] 4.684095 4.180205 4.211515
#> [15,] 3.757030 4.076109 4.179957
#> [16,] 4.043497 3.991468 4.254156
#> TCTCTAACAGAGTGTG-r17 TCTCTAAGTCTTTCAT-r17 TCTGAGAGTGCCTGTG-r17
#> [1,] 4.277369 4.269781 4.402408
#> [2,] 4.150414 4.459683 3.976553
#> [3,] 4.104876 4.070083 4.451838
#> [4,] 4.163753 4.090430 3.846641
#> [5,] 5.011960 5.077619 4.617871
#> [6,] 4.137534 4.278071 4.166667
#> [7,] 4.936523 4.535795 4.423954
#> [8,] 4.465041 4.841748 4.485425
#> [9,] 4.092916 4.601356 4.287072
#> [10,] 4.172493 4.306707 4.162231
#> [11,] 4.166513 4.147702 4.493029
#> [12,] 3.911684 4.520723 4.636882
#> [13,] 4.189052 3.949510 4.391635
#> [14,] 4.383165 4.490580 4.041825
#> [15,] 3.982981 4.262999 4.014575
#> [16,] 4.204232 4.516956 4.294043
#> TCTTCGGGTCGCATCG-r17 TGAAAGATCCTCATTA-r17 TGACAACTCTGCGACG-r17
#> [1,] 4.423848 4.310421 4.036725
#> [2,] 4.169339 4.008161 4.205815
#> [3,] 4.234469 4.112053 4.459832
#> [4,] 4.650301 4.350596 4.129304
#> [5,] 4.477956 4.984934 4.755930
#> [6,] 4.574148 4.026365 4.452946
#> [7,] 4.145291 5.054614 4.368018
#> [8,] 4.786573 4.622724 4.719969
#> [9,] 4.665331 4.099498 4.505738
#> [10,] 4.301603 4.010044 4.345065
#> [11,] 4.422846 4.195857 4.144606
#> [12,] 4.270541 3.982109 4.481255
#> [13,] 4.332665 4.086629 4.371844
#> [14,] 4.486974 4.390144 3.864575
#> [15,] 4.132265 3.908977 4.280031
#> [16,] 4.131263 4.251726 4.452946
#> TGACGGCCAATCACAC-r17 TGACTTTTCCAGTAGT-r17 TGACTTTTCGTGACAT-r17
#> [1,] 4.123561 4.289003 4.254
#> [2,] 4.251363 4.306905 4.324
#> [3,] 4.417323 4.065217 4.314
#> [4,] 4.184737 4.010230 4.241
#> [5,] 4.586311 4.609974 4.595
#> [6,] 4.263477 3.710997 4.389
#> [7,] 4.296790 4.235294 4.615
#> [8,] 4.477286 5.108696 4.862
#> [9,] 4.427620 4.483376 4.372
#> [10,] 4.600242 4.023018 4.413
#> [11,] 4.301030 3.824808 3.980
#> [12,] 4.190188 4.143223 4.570
#> [13,] 4.296184 4.740409 4.487
#> [14,] 4.173228 4.190537 4.230
#> [15,] 4.269534 4.109974 4.437
#> [16,] 4.438522 4.423274 4.754
#> TGAGAGGTCAAGGTAA-r17 TGAGCATTCATCACCC-r17 TGAGCCGAGTGAAGAG-r17
#> [1,] 4.345890 4.303612 4.095436
#> [2,] 4.379452 4.077878 4.455740
#> [3,] 4.260959 3.911964 4.186030
#> [4,] 4.253425 3.920993 3.931535
#> [5,] 4.881507 4.939052 4.398340
#> [6,] 4.194521 3.998871 3.836100
#> [7,] 4.365068 4.147856 4.384509
#> [8,] 4.634247 4.764108 4.882434
#> [9,] 4.397945 4.121896 4.336791
#> [10,] 4.158904 4.146727 4.052559
#> [11,] 4.294521 4.313770 4.399032
#> [12,] 4.389726 4.038375 4.479253
#> [13,] 4.382877 4.242664 4.253112
#> [14,] 4.406164 4.269752 4.419087
#> [15,] 4.362329 4.267494 4.269018
#> [16,] 4.293151 4.167043 4.695712
#> TGAGCCGCACGAGAGT-r17 TGAGGGATCCTCATTA-r17 TGATTTCTCACCAGGC-r17
#> [1,] 3.998609 4.266579 4.317161
#> [2,] 4.274687 4.218489 4.472597
#> [3,] 4.287204 4.244620 4.174304
#> [4,] 4.240612 4.257795 4.106918
#> [5,] 4.614743 5.046992 5.017071
#> [6,] 4.111266 4.321256 4.522013
#> [7,] 4.509040 4.670400 4.680144
#> [8,] 4.831015 4.558191 4.835580
#> [9,] 4.022949 4.284146 4.221024
#> [10,] 4.473574 4.370444 4.346810
#> [11,] 4.300417 4.244620 4.328841
#> [12,] 4.456189 4.235617 4.548967
#> [13,] 4.340056 4.159859 4.000000
#> [14,] 4.162726 4.109794 4.210243
#> [15,] 4.164812 4.048748 4.282120
#> [16,] 4.147427 4.432367 4.568733
#> TGATTTCTCAGGATCT-r17 TGATTTCTCCGTACAA-r17 TGCACCTAGCTGCAAG-r17
#> [1,] 4.602333 4.219107 4.452652
#> [2,] 3.943266 3.796754 4.202314
#> [3,] 3.993637 4.023608 4.050723
#> [4,] 4.003712 4.267429 4.159499
#> [5,] 4.997879 5.144596 5.019479
#> [6,] 4.026511 4.126890 4.110511
#> [7,] 4.576882 4.772040 4.591128
#> [8,] 4.669671 4.278495 4.665188
#> [9,] 4.188759 3.886758 4.010800
#> [10,] 4.048250 4.020657 4.146962
#> [11,] 4.192471 4.082995 4.227965
#> [12,] 4.130965 4.253781 4.214079
#> [13,] 4.177625 4.293250 4.048602
#> [14,] 4.318664 4.229805 4.197300
#> [15,] 4.229056 4.243453 3.997493
#> [16,] 4.485684 4.309480 4.196528
#> TGCACCTGTCGTTGTA-r17 TGCCAAAAGGAGTAGA-r17 TGCCAAAGTTATCACG-r17
#> [1,] 4.347023 4.568444 4.311100
#> [2,] 4.054073 4.370317 4.175511
#> [3,] 4.416153 4.252882 4.203262
#> [4,] 4.164956 4.144092 4.175268
#> [5,] 4.848734 4.683718 5.064508
#> [6,] 4.276523 4.170029 3.995618
#> [7,] 4.778234 4.128963 4.765823
#> [8,] 4.466119 4.878963 4.511685
#> [9,] 4.301164 4.392651 4.206670
#> [10,] 4.684463 4.343660 4.059640
#> [11,] 4.345654 4.138329 4.191821
#> [12,] 4.416153 4.299712 4.127313
#> [13,] 4.339493 4.800432 4.196933
#> [14,] 4.431896 4.315562 4.441577
#> [15,] 4.070500 4.146974 4.133642
#> [16,] 4.450376 4.313401 4.186709
#> TGCCCATCAGACTCGC-r17 TGCCCTACACCACCAG-r17 TGCGCAGCACTGAAGG-r17
#> [1,] 4.306982 4.361672 4.171034
#> [2,] 4.329569 3.780488 4.124138
#> [3,] 4.102669 3.948432 4.646897
#> [4,] 3.992300 4.282927 4.110345
#> [5,] 4.721253 5.091289 4.608276
#> [6,] 4.183778 3.952613 4.024828
#> [7,] 4.453285 4.765854 4.478621
#> [8,] 4.585216 4.685714 4.722759
#> [9,] 4.213039 3.924042 4.368276
#> [10,] 4.563655 3.896167 4.179310
#> [11,] 4.143224 4.164460 4.262069
#> [12,] 4.276181 3.999303 4.408276
#> [13,] 4.046715 4.344251 4.027586
#> [14,] 4.379363 4.361672 4.457931
#> [15,] 4.316735 4.218118 4.475862
#> [16,] 4.237166 3.979791 4.467586
#> TGCGCAGGTAAGTGTA-r17 TGCGCAGGTCTCGTTC-r17 TGCGTGGAGGCTCAGA-r17
#> [1,] 4.298851 4.655767 4.335426
#> [2,] 4.262069 3.775862 4.503139
#> [3,] 4.188506 4.080262 4.109417
#> [4,] 4.206130 3.997622 4.266368
#> [5,] 5.117241 4.893579 4.935426
#> [6,] 4.072797 4.094530 4.088789
#> [7,] 4.367050 4.597503 4.203587
#> [8,] 4.484291 4.359691 4.893274
#> [9,] 4.303448 4.263377 4.154260
#> [10,] 4.209195 4.049941 4.493274
#> [11,] 3.855939 4.262188 3.978475
#> [12,] 4.185441 4.080856 4.433184
#> [13,] 4.308812 4.353746 4.279821
#> [14,] 3.937931 4.433413 4.177578
#> [15,] 4.304215 3.911415 4.197309
#> [16,] 4.370881 4.010702 4.658296
#> TGCGTGGAGGGATCTG-r17 TGCGTGGTCCTCTAGC-r17 TGCGTGGTCGCCATAA-r17
#> [1,] 4.551476 4.481707 4.262058
#> [2,] 4.035277 4.022561 4.225080
#> [3,] 4.165587 4.115854 4.348071
#> [4,] 4.156947 4.490854 4.184887
#> [5,] 5.356371 4.945122 4.735531
#> [6,] 3.579554 3.992683 4.277331
#> [7,] 4.965443 4.592073 4.493569
#> [8,] 4.367891 4.530488 4.679260
#> [9,] 4.120230 3.765854 4.601286
#> [10,] 3.976962 4.089634 4.352090
#> [11,] 4.290857 4.210366 4.313505
#> [12,] 3.903528 4.027439 4.561093
#> [13,] 4.092873 4.026829 4.811897
#> [14,] 4.288697 4.259146 4.194534
#> [15,] 4.224622 4.207317 3.966238
#> [16,] 4.208063 4.453049 4.319936
#> TGCTGCTTCCAAACTG-r17 TGCTGCTTCTGTACGA-r17 TGGCGCAAGAGGTTGC-r17
#> [1,] 4.139987 4.269690 4.514160
#> [2,] 4.348023 4.103279 4.486208
#> [3,] 4.014258 4.017162 4.111070
#> [4,] 4.173688 4.061600 4.129092
#> [5,] 4.510693 5.097150 4.665686
#> [6,] 4.228775 3.999694 4.522986
#> [7,] 4.583927 5.085504 4.286135
#> [8,] 4.689566 4.542446 4.755425
#> [9,] 4.233960 4.203800 4.082751
#> [10,] 4.517822 4.263255 4.572269
#> [11,] 4.257291 4.291756 4.237587
#> [12,] 4.666235 4.174686 4.344244
#> [13,] 4.497732 4.240270 4.397573
#> [14,] 4.068697 4.353969 4.336153
#> [15,] 4.561244 4.063132 4.287238
#> [16,] 4.361633 4.130555 4.171387
#> TGGCGCAAGGTAAACT-r17 TGGCGCATCTTACCTA-r17 TGGGCGTAGTCATGCT-r17
#> [1,] 4.427119 4.188850 4.172499
#> [2,] 3.824294 4.294077 4.040457
#> [3,] 4.254237 4.360976 4.235542
#> [4,] 4.106780 4.220906 4.208985
#> [5,] 5.040678 4.858537 5.077687
#> [6,] 3.964407 4.111498 4.231323
#> [7,] 4.399435 4.429965 4.820055
#> [8,] 4.488701 4.766551 4.422437
#> [9,] 4.105085 4.350523 4.044180
#> [10,] 3.976271 4.438328 4.205510
#> [11,] 4.412994 4.150523 4.203276
#> [12,] 4.019209 4.280836 4.357409
#> [13,] 4.132203 4.272474 4.156863
#> [14,] 4.437853 4.144948 4.300819
#> [15,] 4.043503 4.509408 3.929511
#> [16,] 4.181921 4.434843 4.198809
#> TGGGCGTTCTGCTGCT-r17 TGGTTAGAGACAGAGA-r17 TGGTTAGAGGATGGTC-r17
#> [1,] 4.734421 4.456434 4.441026
#> [2,] 3.807612 3.805978 4.453205
#> [3,] 4.274362 4.231510 3.936538
#> [4,] 4.357173 4.302432 4.243590
#> [5,] 4.648264 4.489362 4.508333
#> [6,] 4.112087 3.925025 4.257692
#> [7,] 4.466332 4.448835 4.055128
#> [8,] 4.438729 4.295339 5.051282
#> [9,] 4.140527 4.223404 4.399359
#> [10,] 3.918862 4.044580 4.814744
#> [11,] 4.376830 4.048126 4.037821
#> [12,] 4.400251 4.301925 4.196795
#> [13,] 4.331242 4.386525 4.503205
#> [14,] 4.276872 4.509119 4.361538
#> [15,] 4.141363 4.306991 4.005128
#> [16,] 4.003764 4.286221 4.383974
#> TGGTTAGGTGACAAAT-r17 TGGTTCCAGCCGCCTA-r17 TGGTTCCCACTGTGTA-r17
#> [1,] 4.268632 4.612971 4.319656
#> [2,] 4.042316 4.435146 4.312023
#> [3,] 4.001684 4.062762 4.045802
#> [4,] 3.981263 4.074268 3.941794
#> [5,] 5.440842 4.825314 5.130725
#> [6,] 4.220000 4.469665 4.437023
#> [7,] 4.961263 4.420502 4.345420
#> [8,] 4.436211 4.741632 4.601145
#> [9,] 3.988842 4.205021 4.227099
#> [10,] 4.005895 4.446653 4.554389
#> [11,] 4.159158 4.412134 4.075382
#> [12,] 4.232211 4.484310 4.334924
#> [13,] 3.983158 4.398536 4.089695
#> [14,] 4.242737 3.921548 4.373092
#> [15,] 4.036000 4.064854 3.894084
#> [16,] 4.313684 4.496862 4.394084
#> TGTCCCAGTGAGCGAT-r17 TGTCCCATCAAGAAGT-r17 TGTCCCATCGTTTGCC-r17
#> [1,] 4.174545 4.277036 4.636528
#> [2,] 4.282586 4.081422 4.020344
#> [3,] 4.215879 4.180741 4.331826
#> [4,] 4.394516 4.349130 4.480108
#> [5,] 4.988336 5.232417 4.808770
#> [6,] 4.184367 4.156037 4.030289
#> [7,] 4.765910 4.723721 4.570524
#> [8,] 4.543483 4.453491 4.370253
#> [9,] 4.233681 4.157802 4.122514
#> [10,] 4.157152 4.054197 4.015823
#> [11,] 4.377532 4.300479 4.089060
#> [12,] 4.153878 4.187547 4.056962
#> [13,] 4.194598 4.014116 4.183092
#> [14,] 4.505832 4.422233 4.305606
#> [15,] 3.972990 3.997227 4.138788
#> [16,] 4.196440 4.118982 4.190325
#> TGTGGTACACCAGGTC-r17 TGTGTTTCAGCTGTTA-r17 TTATGCTCACCCATGG-r17
#> [1,] 4.160078 4.218391 4.289474
#> [2,] 4.139535 4.068966 4.008581
#> [3,] 4.291085 4.540230 3.924485
#> [4,] 4.283721 4.344061 4.255721
#> [5,] 5.151163 4.828352 5.137872
#> [6,] 4.141473 3.927203 4.164760
#> [7,] 4.800775 4.809962 4.910183
#> [8,] 4.542248 4.732567 4.565789
#> [9,] 4.082558 3.824521 4.119565
#> [10,] 4.238372 4.242146 4.215103
#> [11,] 4.220543 4.357854 4.062929
#> [12,] 4.226744 4.016092 4.000572
#> [13,] 4.234109 4.148659 4.029176
#> [14,] 4.333333 4.357088 4.278604
#> [15,] 4.146124 3.993870 3.977117
#> [16,] 4.216667 4.053640 4.215103
#> TTATGCTTCTAACTCT-r17 TTCGAAGAGGGAAACA-r17 TTCGAAGAGTGAAGAG-r17
#> [1,] 4.385133 4.424198 4.400588
#> [2,] 4.123793 4.085946 4.586680
#> [3,] 4.242318 4.240133 4.235064
#> [4,] 4.241733 4.150867 4.314398
#> [5,] 4.919813 4.927702 4.831538
#> [6,] 4.228563 3.953523 4.342801
#> [7,] 4.357624 4.668388 4.431929
#> [8,] 4.571847 4.566581 4.629775
#> [9,] 4.346795 4.342309 4.519099
#> [10,] 4.338601 4.106603 4.556317
#> [11,] 4.147498 4.266322 4.072478
#> [12,] 4.317530 4.234969 4.473066
#> [13,] 4.278022 4.231280 4.242899
#> [14,] 4.305531 4.465880 4.416259
#> [15,] 4.066433 4.108447 4.230167
#> [16,] 4.323676 4.274069 4.336925
#> TTCGGTCTCAGTGTTG-r17 TTCTACACAAAGGTGC-r17 TTCTACACATCCAACA-r17
#> [1,] 4.010025 4.398829 4.159475
#> [2,] 4.213033 4.436565 4.037648
#> [3,] 4.243108 4.407938 4.044839
#> [4,] 4.139098 4.076773 4.113790
#> [5,] 4.697995 5.422902 4.913706
#> [6,] 4.226817 4.685751 3.996193
#> [7,] 4.448622 4.636304 4.862944
#> [8,] 4.972431 4.938842 4.695431
#> [9,] 4.492481 4.459987 4.144670
#> [10,] 4.502506 4.057254 3.994501
#> [11,] 4.244361 4.212752 4.291455
#> [12,] 4.340852 4.547820 3.947970
#> [13,] 4.775689 4.093038 4.109560
#> [14,] 4.208020 3.996747 4.518190
#> [15,] 4.315789 4.043591 3.988156
#> [16,] 4.645363 4.717632 3.988579
#> TTCTCAATCCATGAAC-r17 TTCTCAATCTGTCAAG-r17 TTCTCCTTCTTAGAGC-r17
#> [1,] 4.306812 4.659231 4.583333
#> [2,] 3.864275 4.026578 4.446860
#> [3,] 4.308372 4.313716 4.222222
#> [4,] 4.253250 4.405790 4.252415
#> [5,] 4.917317 5.027053 4.574879
#> [6,] 3.985439 3.934029 4.681159
#> [7,] 4.737389 4.638348 4.638889
#> [8,] 4.411856 4.471761 4.663043
#> [9,] 4.043682 4.231134 4.371981
#> [10,] 4.183567 3.840532 4.428744
#> [11,] 4.389496 4.240152 4.402174
#> [12,] 4.143526 4.057902 4.130435
#> [13,] 4.171607 4.145230 4.498792
#> [14,] 4.299532 4.314191 4.295894
#> [15,] 4.014561 4.124347 4.001208
#> [16,] 4.245450 4.224964 4.810386
#> TTGACTTTCGAGCCCA-r17 TTGCCGTAGAGGTAGA-r17 TTGGAACGTTCGAATC-r17
#> [1,] 4.290381 4.319549 4.181098
#> [2,] 4.322444 4.405075 4.611585
#> [3,] 4.367816 4.019737 4.487195
#> [4,] 4.309740 4.031015 4.243902
#> [5,] 4.799758 4.986842 4.740244
#> [6,] 4.436782 4.232143 4.224390
#> [7,] 4.376286 4.205827 4.453049
#> [8,] 4.970357 4.978383 4.851220
#> [9,] 4.522686 4.352444 4.240244
#> [10,] 4.461585 4.136278 4.269512
#> [11,] 4.367211 4.438910 4.306098
#> [12,] 4.616455 4.038534 4.254268
#> [13,] 3.985481 4.209586 4.184146
#> [14,] 4.442831 4.416353 4.604268
#> [15,] 4.128857 4.032895 4.074390
#> [16,] 4.289171 4.635338 4.218902
#> TTGGCAAAGTTAGCGG-r17 TTGGCAACAAGAAGAG-r17 TTGTAGGGTCTTCAAG-r17
#> [1,] 4.372585 4.473214 4.513766
#> [2,] 3.671113 4.013951 4.167532
#> [3,] 4.236431 4.133929 4.245455
#> [4,] 4.372585 4.090960 4.298442
#> [5,] 5.021619 5.159598 5.122078
#> [6,] 4.185373 4.030134 4.049610
#> [7,] 4.762649 4.696987 4.796104
#> [8,] 4.330727 4.429687 4.308831
#> [9,] 4.039558 4.181362 3.853766
#> [10,] 4.250230 4.103237 4.216104
#> [11,] 4.135695 4.092634 4.163896
#> [12,] 4.148114 4.016741 4.284675
#> [13,] 4.354646 4.097656 4.145974
#> [14,] 4.301288 4.590402 4.162078
#> [15,] 4.221711 3.862165 4.161299
#> [16,] 3.899264 3.872768 4.223896
#> TTGTAGGGTCTTCTCG-r17 TTGTAGGTCCGCTGTT-r17 TTGTAGGTCCTTGGTC-r17
#> [1,] 4.366463 4.367242 4.158232
#> [2,] 3.954573 4.155470 4.494555
#> [3,] 4.067073 4.324376 4.384369
#> [4,] 4.412500 4.085413 4.228059
#> [5,] 4.910061 5.463532 4.584881
#> [6,] 4.080488 4.321497 4.066624
#> [7,] 4.835061 4.752399 4.466368
#> [8,] 4.357317 4.588292 4.900064
#> [9,] 4.117378 3.928983 4.230621
#> [10,] 4.049390 4.146833 4.547085
#> [11,] 4.031707 4.436660 4.335682
#> [12,] 4.083537 4.331414 4.430493
#> [13,] 4.203049 3.927383 4.187060
#> [14,] 4.406707 4.143314 4.377322
#> [15,] 3.990549 4.170186 4.190903
#> [16,] 4.013110 4.553103 4.455477
#> TTTACTGAGTGGGCTA-r17 TTTACTGTCTCTGCTG-r17 TTTCCTCCATTCTCAT-r17
#> [1,] 4.106613 4.190321 4.395114
#> [2,] 4.465587 4.045133 3.918893
#> [3,] 4.612686 4.073681 3.979153
#> [4,] 4.294197 4.331702 4.317264
#> [5,] 4.789474 5.053018 5.129642
#> [6,] 3.798920 4.145731 3.807818
#> [7,] 4.634278 4.852637 5.046580
#> [8,] 4.491228 4.430261 4.431270
#> [9,] 4.395412 4.172920 4.160912
#> [10,] 4.171390 4.212208 4.009772
#> [11,] 4.477733 4.266449 4.107166
#> [12,] 4.449393 4.113241 4.012052
#> [13,] 4.396761 4.137031 4.116287
#> [14,] 4.287449 4.466286 4.344300
#> [15,] 4.295547 3.927542 3.922801
#> [16,] 4.002699 4.180533 3.932899
#> TTTCCTCGTCATTAGC-r17 TTTCCTCGTCTCAACA-r17 TTTGGTTCATGGTAGG-r17
#> [1,] 4.556282 4.218927 4.260496
#> [2,] 3.879496 4.030014 4.245229
#> [3,] 3.919664 4.387712 4.103053
#> [4,] 4.057450 4.088630 4.449427
#> [5,] 5.246147 4.783545 4.291985
#> [6,] 3.770201 4.140184 4.243321
#> [7,] 4.794956 4.458333 4.680344
#> [8,] 4.223727 4.526483 4.797710
#> [9,] 3.916394 4.100989 4.495229
#> [10,] 3.951892 4.264477 4.264313
#> [11,] 4.160206 4.150424 4.339695
#> [12,] 3.790285 4.274718 4.437977
#> [13,] 4.049510 4.104167 4.727099
#> [14,] 4.562354 4.302966 4.167939
#> [15,] 3.797758 4.405720 4.261450
#> [16,] 4.297525 4.561088 4.371183
#> TTTGTCAAGCACCGCT-r17 AAACGGGGTAGCACGA-b01 AAACGGGTCGGTCCGA-b01
#> [1,] 4.906082 4.298667 4.406343
#> [2,] 4.389088 3.929333 4.266601
#> [3,] 4.462433 4.218667 4.528246
#> [4,] 4.035778 4.442667 4.183350
#> [5,] 4.720036 4.384000 4.182359
#> [6,] 4.509839 3.950667 4.734390
#> [7,] 4.424866 4.456000 3.976214
#> [8,] 4.880143 4.857333 4.917740
#> [9,] 4.603757 4.550667 4.279485
#> [10,] 4.728980 4.253333 4.121903
#> [11,] 4.435599 4.257333 4.291378
#> [12,] 4.516100 4.622667 4.479683
#> [13,] 4.635063 4.654667 4.351833
#> [14,] 4.272809 4.510667 4.405352
#> [15,] 4.161896 4.941333 4.233895
#> [16,] 4.552773 4.496000 4.718533
#> AAAGCAACAGATGGGT-b01 AAATGCCCACAACGCC-b01 AAATGCCCATGCGCAC-b01
#> [1,] 4.236981 4.075702 4.508018
#> [2,] 4.179623 4.694750 4.366260
#> [3,] 4.238868 4.446886 4.211674
#> [4,] 4.176604 4.531136 4.422065
#> [5,] 4.990566 4.012210 4.508018
#> [6,] 4.093962 3.904762 4.138550
#> [7,] 4.874340 4.323565 4.187941
#> [8,] 4.395472 4.916972 4.926876
#> [9,] 4.158868 4.892552 4.423348
#> [10,] 4.170566 4.318681 4.226427
#> [11,] 4.360377 4.196581 4.165491
#> [12,] 4.292830 4.652015 4.339320
#> [13,] 4.261132 4.221001 4.801796
#> [14,] 4.398868 4.390720 4.100064
#> [15,] 3.863396 4.528694 4.234124
#> [16,] 4.109811 3.898657 4.375882
#> AAATGCCGTCGCTTCT-b01 AACACGTCATGGTTGT-b01 AACACGTGTTGTTTGG-b01
#> [1,] 4.257019 4.521307 4.669613
#> [2,] 4.362851 4.029830 4.223204
#> [3,] 4.349892 4.427557 3.955801
#> [4,] 4.193305 4.534091 4.160221
#> [5,] 4.214903 4.609375 4.708287
#> [6,] 4.318575 4.336648 4.277348
#> [7,] 4.629590 4.386364 4.209945
#> [8,] 4.717063 5.183239 5.107182
#> [9,] 4.561555 4.741477 4.111602
#> [10,] 4.502160 4.426136 3.970166
#> [11,] 4.724622 4.225852 4.466298
#> [12,] 4.590713 4.674716 4.038674
#> [13,] 4.246220 4.096591 4.558011
#> [14,] 4.809935 4.117898 4.538122
#> [15,] 4.421166 4.545455 4.090608
#> [16,] 4.291577 4.213068 4.681768
#> AACCATGCATTAGCCA-b01 AACTCAGAGATAGGAG-b01 AACTCAGTCCGTCAAA-b01
#> [1,] 4.724390 4.196386 4.321957
#> [2,] 4.317073 4.366265 4.433447
#> [3,] 4.306098 5.143373 4.078498
#> [4,] 4.470732 4.515663 3.833902
#> [5,] 4.309756 4.255422 4.862344
#> [6,] 4.371951 4.145783 3.642776
#> [7,] 4.217073 4.363855 3.863481
#> [8,] 4.595122 4.934940 5.075085
#> [9,] 4.262195 4.863855 4.604096
#> [10,] 4.510976 4.738554 4.004551
#> [11,] 4.107317 4.657831 4.634812
#> [12,] 4.268293 4.602410 4.325370
#> [13,] 4.624390 4.142169 4.676906
#> [14,] 4.162195 4.071084 4.621160
#> [15,] 4.173171 4.539759 3.766780
#> [16,] 4.348780 4.162651 4.327645
#> AACTGGTAGATGTGGC-b01 AACTGGTCAAACCTAC-b01 AACTTTCAGTGAATTG-b01
#> [1,] 4.445630 4.378766 4.127238
#> [2,] 3.965310 4.206600 4.220075
#> [3,] 4.131421 4.451937 4.373704
#> [4,] 4.092061 4.340029 4.224317
#> [5,] 4.884590 4.612626 4.825636
#> [6,] 4.236825 4.308465 4.211593
#> [7,] 4.924616 4.358680 4.958058
#> [8,] 4.776518 5.096126 4.396324
#> [9,] 4.344229 4.355811 4.348728
#> [10,] 4.081388 4.510760 4.225730
#> [11,] 4.352902 4.298422 4.241753
#> [12,] 4.325550 4.328551 4.035815
#> [13,] 3.941961 4.655667 4.291235
#> [14,] 4.498332 4.202296 4.671065
#> [15,] 4.290193 4.463415 3.886428
#> [16,] 3.908606 4.427547 4.131951
#> AACTTTCGTTCCACGG-b01 AACTTTCTCGCTTAGA-b01 AAGACCTAGCGTTCCG-b01
#> [1,] 4.713907 4.585927 4.428673
#> [2,] 4.466225 4.382950 3.723208
#> [3,] 4.238411 4.332882 4.020582
#> [4,] 4.300662 4.324763 4.234209
#> [5,] 4.544371 4.635995 4.684883
#> [6,] 4.350993 4.380244 3.933286
#> [7,] 4.246358 4.060893 4.744500
#> [8,] 4.801325 4.640054 4.787083
#> [9,] 4.410596 4.377537 4.342796
#> [10,] 4.162914 4.303112 4.215756
#> [11,] 4.450331 4.267930 4.434351
#> [12,] 4.492715 4.786198 4.224982
#> [13,] 4.548344 4.795670 4.355571
#> [14,] 4.463576 3.755074 4.755855
#> [15,] 4.239735 4.112314 3.900639
#> [16,] 4.084768 4.186739 3.906317
#> AAGACCTAGTCTCCTC-b01 AAGACCTGTGTTGAGG-b01 AAGGAGCGTATGCTTG-b01
#> [1,] 4.768620 4.426052 4.717054
#> [2,] 3.537239 4.025780 4.351421
#> [3,] 3.946375 4.493894 4.524548
#> [4,] 4.345581 4.160109 4.151163
#> [5,] 4.619662 4.810041 4.675711
#> [6,] 4.107249 4.290366 4.067183
#> [7,] 4.517378 4.451832 4.165375
#> [8,] 4.453823 4.938942 4.905685
#> [9,] 4.057597 4.436906 4.041344
#> [10,] 3.857001 3.807327 4.280362
#> [11,] 4.612711 3.947083 4.120155
#> [12,] 4.313803 4.328358 4.291990
#> [13,] 4.211519 4.720488 4.581395
#> [14,] 4.148957 4.412483 4.195090
#> [15,] 4.026812 3.944369 4.027132
#> [16,] 3.865938 4.720488 4.317829
#> AAGGAGCTCAGCACAT-b01 AAGGTTCCAATAGAGT-b01 AATCCAGAGCTGCGAA-b01
#> [1,] 4.265586 4.476868 4.306625
#> [2,] 3.871571 4.093416 3.832587
#> [3,] 4.394015 4.178826 4.069382
#> [4,] 4.066085 4.040036 4.372426
#> [5,] 4.865337 4.764235 5.145927
#> [6,] 4.269327 3.951957 4.085944
#> [7,] 4.743142 4.440391 5.048791
#> [8,] 4.382793 4.599644 4.405551
#> [9,] 4.583541 4.342527 4.269024
#> [10,] 4.074813 3.879004 4.021486
#> [11,] 4.183292 4.083630 4.116383
#> [12,] 4.104738 4.207295 4.122650
#> [13,] 4.466334 4.526690 4.234109
#> [14,] 4.311721 4.200178 4.411817
#> [15,] 3.987531 4.328292 3.956132
#> [16,] 4.377805 4.300712 4.157117
#> AATCCAGAGGGAGTAA-b01 AATCCAGCAGCGATCC-b01 AATCGGTAGCGGATCA-b01
#> [1,] 4.582383 4.628141 4.195301
#> [2,] 3.992228 4.334171 3.922173
#> [3,] 4.432642 4.738693 4.055800
#> [4,] 4.304663 4.546482 4.162996
#> [5,] 5.036269 4.438442 5.349486
#> [6,] 4.269948 4.194724 4.078806
#> [7,] 4.720207 4.113065 5.230543
#> [8,] 4.683938 4.616834 4.656877
#> [9,] 4.297927 4.239950 4.154674
#> [10,] 3.831088 4.359296 4.096916
#> [11,] 4.183938 4.135678 4.040137
#> [12,] 4.107772 4.329146 4.112580
#> [13,] 4.137824 4.385678 4.234949
#> [14,] 4.174093 4.258794 4.444444
#> [15,] 4.023834 4.340452 4.028390
#> [16,] 4.130052 4.523869 3.765051
#> ACACCGGGTGTAAGTA-b01 ACACCGGGTTATCGGT-b01 ACACTGACAAGACACG-b01
#> [1,] 4.403983 4.183544 4.274860
#> [2,] 4.423898 4.122061 4.226816
#> [3,] 4.064011 4.496383 4.356425
#> [4,] 4.635846 4.192586 4.184358
#> [5,] 4.192034 4.489150 4.750838
#> [6,] 4.189189 4.052441 4.572067
#> [7,] 3.935989 4.564195 4.437989
#> [8,] 5.496444 4.500904 5.233520
#> [9,] 4.640114 4.378843 4.949721
#> [10,] 3.881935 4.310127 4.446927
#> [11,] 4.177809 4.233273 4.525140
#> [12,] 4.678521 4.291139 4.382123
#> [13,] 4.155050 4.055154 4.021229
#> [14,] 4.862020 4.071429 4.452514
#> [15,] 4.453770 4.592224 4.254749
#> [16,] 3.958748 4.168174 4.156425
#> ACACTGATCCCTAATT-b01 ACACTGATCTACCTGC-b01 ACAGCCGCAAGTTGTC-b01
#> [1,] 4.034965 4.229730 4.358450
#> [2,] 4.057343 4.320946 3.824543
#> [3,] 4.137063 4.180180 3.922497
#> [4,] 4.688112 4.440315 4.199139
#> [5,] 4.187413 4.345721 5.117330
#> [6,] 4.283916 3.963964 3.907427
#> [7,] 4.302098 4.106982 4.653391
#> [8,] 5.006993 4.953829 4.329386
#> [9,] 4.667133 4.600225 4.125942
#> [10,] 4.187413 4.319820 4.030140
#> [11,] 4.475524 4.355856 3.972013
#> [12,] 4.370629 4.270270 3.909580
#> [13,] 4.331469 4.691441 4.305705
#> [14,] 4.272727 4.467342 4.368138
#> [15,] 3.945455 4.318694 3.838536
#> [16,] 4.201399 4.630631 3.998924
#> ACAGCCGTCAGCACAT-b01 ACAGCCGTCAGGATCT-b01 ACAGCTAGTTATCACG-b01
#> [1,] 4.534562 4.683206 4.324709
#> [2,] 4.103687 4.437405 4.200517
#> [3,] 4.099078 4.217557 4.336352
#> [4,] 4.836406 4.170229 4.419146
#> [5,] 4.707373 4.357252 4.598965
#> [6,] 4.489631 4.095420 4.046572
#> [7,] 4.322581 4.164885 4.258732
#> [8,] 5.406682 5.354198 4.791721
#> [9,] 4.793779 4.313740 4.258732
#> [10,] 4.716590 4.329771 4.165589
#> [11,] 4.622120 4.645802 3.985770
#> [12,] 4.240783 4.474809 4.354463
#> [13,] 4.167051 4.596183 4.241915
#> [14,] 4.379032 4.464885 4.080207
#> [15,] 4.436636 4.006870 4.289780
#> [16,] 4.087558 4.297710 4.125485
#> ACAGCTATCTACTATC-b01 ACATACGAGAGTAATC-b01 ACATACGCAGGACCCT-b01
#> [1,] 4.344148 4.929412 4.531136
#> [2,] 3.678117 3.779832 4.161172
#> [3,] 3.711196 3.857983 4.133089
#> [4,] 4.183206 4.471429 4.018315
#> [5,] 5.447201 5.040336 4.827839
#> [6,] 4.096692 4.016807 4.017094
#> [7,] 5.257634 4.604202 4.394383
#> [8,] 4.256361 4.324370 5.019536
#> [9,] 4.150763 3.931933 4.174603
#> [10,] 3.802163 3.909244 4.051282
#> [11,] 3.896947 3.911765 4.075702
#> [12,] 4.005089 3.859664 4.225885
#> [13,] 4.312341 4.110084 4.351648
#> [14,] 4.501272 4.225210 3.982906
#> [15,] 3.579517 3.979832 4.236874
#> [16,] 3.790076 4.192437 4.312576
#> ACATACGTCAGTTCGA-b01 ACATCAGAGACAGACC-b01 ACATGGTTCAGTTTGG-b01
#> [1,] 4.203125 4.315414 4.485849
#> [2,] 3.860677 3.921558 3.802830
#> [3,] 4.031250 3.936369 3.911321
#> [4,] 4.509115 4.254526 4.180189
#> [5,] 5.191406 5.065277 4.988679
#> [6,] 3.906250 4.080088 3.737736
#> [7,] 4.923177 4.716402 5.008491
#> [8,] 4.313802 4.865606 4.349057
#> [9,] 4.049479 4.501920 4.246226
#> [10,] 3.815104 4.137685 3.667925
#> [11,] 4.148437 4.366978 4.560377
#> [12,] 3.747396 4.038398 3.897170
#> [13,] 3.971354 4.194185 4.128302
#> [14,] 4.572917 4.618212 4.756604
#> [15,] 3.787760 4.080636 3.883962
#> [16,] 3.653646 3.939111 3.915094
#> ACCAGTATCTATCGCC-b01 ACCGTAAAGACACGAC-b01 ACCGTAAGTATAGGGC-b01
#> [1,] 4.367284 4.333569 4.433618
#> [2,] 4.206019 3.902975 4.133983
#> [3,] 4.447531 3.965297 4.422655
#> [4,] 4.180556 4.156516 4.218027
#> [5,] 4.562500 5.431303 4.557856
#> [6,] 4.337963 3.914306 4.097442
#> [7,] 4.464506 5.160765 4.450670
#> [8,] 4.722222 4.248584 4.739342
#> [9,] 4.623457 3.959632 4.343484
#> [10,] 4.202160 3.672096 4.319123
#> [11,] 4.378086 3.979462 4.627284
#> [12,] 4.398920 3.839943 4.427527
#> [13,] 4.531636 4.002833 4.226553
#> [14,] 4.313272 4.585694 4.124239
#> [15,] 4.164352 3.774079 4.176614
#> [16,] 4.141975 3.858357 4.230207
#> ACCTTTAAGGCCGAAT-b01 ACCTTTATCCAGTATG-b01 ACCTTTATCCATGAAC-b01
#> [1,] 4.282486 4.460203 4.639290
#> [2,] 4.333333 4.261939 3.908990
#> [3,] 4.512712 4.716353 4.400666
#> [4,] 4.355932 4.538350 4.306326
#> [5,] 4.430791 4.651230 5.116537
#> [6,] 4.391243 4.092619 4.089900
#> [7,] 4.634181 4.500724 4.823529
#> [8,] 4.795198 4.848046 4.509434
#> [9,] 4.744350 4.321274 4.221976
#> [10,] 4.247175 4.160637 3.915649
#> [11,] 4.459040 4.147612 4.251942
#> [12,] 4.540960 4.183792 4.197558
#> [13,] 4.679379 4.509407 4.213097
#> [14,] 4.209040 4.124457 4.049945
#> [15,] 4.166667 4.325615 4.000000
#> [16,] 4.437853 4.052098 4.017758
#> ACGAGGACATCACGAT-b01 ACGAGGACATTGGGCC-b01 ACGAGGAGTGCTAGCC-b01
#> [1,] 4.555766 4.170439 4.698318
#> [2,] 3.958412 4.215712 4.074184
#> [3,] 4.289225 4.446738 4.174085
#> [4,] 4.404537 4.571904 4.221563
#> [5,] 5.054820 4.400133 4.800198
#> [6,] 4.132325 4.264980 4.138477
#> [7,] 4.030246 4.024634 4.402572
#> [8,] 4.363894 5.079893 5.003956
#> [9,] 4.623819 4.796937 4.316518
#> [10,] 4.118147 4.337550 4.149357
#> [11,] 4.140832 4.688415 3.980218
#> [12,] 4.391304 4.376165 4.316518
#> [13,] 4.587902 4.268309 4.378833
#> [14,] 4.560491 4.375499 4.249258
#> [15,] 3.903592 4.331558 4.173096
#> [16,] 3.929112 4.260985 4.199802
#> ACGATACCAGTGAGTG-b01 ACGCCAGTCTCGCATC-b01 ACGCCGAGTCTCCCTA-b01
#> [1,] 4.444349 4.344828 4.076108
#> [2,] 3.551370 4.321839 4.485549
#> [3,] 4.012842 4.431673 4.321773
#> [4,] 4.434932 3.961686 4.136802
#> [5,] 4.730308 4.789272 4.220617
#> [6,] 3.849315 4.535121 4.056840
#> [7,] 4.868151 4.143040 4.227360
#> [8,] 4.523973 5.389527 5.155106
#> [9,] 4.410959 4.647510 4.649326
#> [10,] 3.693493 4.727969 4.049133
#> [11,] 3.930651 5.143040 4.467245
#> [12,] 4.244863 4.398467 4.427746
#> [13,] 4.251712 4.176245 4.358382
#> [14,] 4.650685 4.398467 4.062620
#> [15,] 3.821062 3.936143 4.109827
#> [16,] 3.893836 4.909323 4.570328
#> ACGCCGAGTTCGTGAT-b01 ACGCCGATCAGCAACT-b01 ACGCCGATCCGTTGTC-b01
#> [1,] 4.363765 4.482365 4.567503
#> [2,] 3.925733 4.515560 4.311828
#> [3,] 4.167928 4.320539 4.155317
#> [4,] 4.522706 4.327801 4.800478
#> [5,] 5.222800 4.852697 4.968937
#> [6,] 4.245033 4.133817 4.149343
#> [7,] 4.952696 4.483402 4.737157
#> [8,] 4.263009 4.709544 4.874552
#> [9,] 4.196783 3.975104 4.413381
#> [10,] 4.160360 4.188797 4.223417
#> [11,] 4.251183 4.257261 4.270012
#> [12,] 4.125355 4.066390 4.223417
#> [13,] 4.369915 4.000000 4.286738
#> [14,] 4.263482 4.661826 4.354839
#> [15,] 4.000946 4.260373 4.084827
#> [16,] 4.220435 3.946058 3.989247
#> ACGGAGACATGTTCCC-b01 ACGGAGATCTCGCATC-b01 ACGGGCTTCAACACCA-b01
#> [1,] 4.172487 4.004202 4.555280
#> [2,] 3.673016 4.284314 4.206211
#> [3,] 3.782011 4.337535 4.675776
#> [4,] 4.387302 4.865546 4.381366
#> [5,] 5.173545 4.348739 4.765217
#> [6,] 4.068783 3.952381 4.785093
#> [7,] 4.946032 4.414566 4.514286
#> [8,] 4.433862 4.581232 4.988820
#> [9,] 4.183069 4.953782 4.568944
#> [10,] 3.898413 4.378151 4.382609
#> [11,] 4.037037 4.217087 4.740373
#> [12,] 3.865608 4.390756 4.786335
#> [13,] 4.027513 4.148459 4.170186
#> [14,] 4.603175 4.154062 4.366460
#> [15,] 3.586243 4.376751 4.344099
#> [16,] 3.792593 4.341737 4.234783
#> ACGGGCTTCAGTTTGG-b01 ACGGGTCGTACCGAGA-b01 ACGGGTCGTCGAGATG-b01
#> [1,] 4.374046 4.389027 4.686047
#> [2,] 4.357824 4.015319 3.900517
#> [3,] 4.442748 4.028500 3.943152
#> [4,] 3.871183 4.350196 4.456072
#> [5,] 5.012405 5.218026 5.112403
#> [6,] 3.994275 4.008194 3.723514
#> [7,] 4.154580 4.793730 5.011628
#> [8,] 4.937977 4.280371 4.550388
#> [9,] 4.333015 4.298896 4.002584
#> [10,] 4.291985 4.078732 4.093023
#> [11,] 4.104962 4.064125 4.138243
#> [12,] 4.375000 4.194157 3.790698
#> [13,] 4.966603 4.343071 4.175711
#> [14,] 4.315840 4.467759 4.529716
#> [15,] 3.887405 3.924475 3.733850
#> [16,] 4.000000 4.064125 4.315245
#> ACGGGTCGTGTTTGGT-b01 ACTGAGTCAACTGCGC-b01 ACTGAGTGTACTTAGC-b01
#> [1,] 3.868256 4.605479 4.028818
#> [2,] 3.810540 4.571233 3.935639
#> [3,] 4.077792 4.408219 4.239193
#> [4,] 3.977415 4.384932 4.480307
#> [5,] 5.353827 4.323288 4.771374
#> [6,] 3.736512 4.187671 4.642651
#> [7,] 5.139272 4.383562 4.618636
#> [8,] 4.483061 5.080822 4.644573
#> [9,] 4.543287 4.265753 4.424592
#> [10,] 3.944793 4.205479 4.079731
#> [11,] 4.126725 4.353425 4.111431
#> [12,] 4.060226 4.602740 4.338136
#> [13,] 4.371393 4.635616 4.349664
#> [14,] 4.664994 4.376712 4.182517
#> [15,] 3.823087 4.121918 4.246878
#> [16,] 3.696361 4.268493 3.807877
#> ACTGAGTGTCTCGTTC-b01 ACTGAGTGTCTGATTG-b01 ACTGAGTGTTGATTGC-b01
#> [1,] 4.372263 4.431017 4.565385
#> [2,] 3.982968 4.211480 4.274359
#> [3,] 4.068127 4.138973 4.248718
#> [4,] 4.329684 4.195368 4.361538
#> [5,] 5.133820 5.059416 4.302564
#> [6,] 3.860097 4.284995 3.907692
#> [7,] 4.766423 4.480363 3.750000
#> [8,] 4.445255 4.614300 5.098718
#> [9,] 4.242092 4.120846 4.166667
#> [10,] 3.896594 3.966767 4.041026
#> [11,] 3.963504 4.193353 4.292308
#> [12,] 4.392944 4.056395 3.726923
#> [13,] 4.173966 4.162135 3.993590
#> [14,] 4.198297 4.704935 4.415385
#> [15,] 4.051095 4.132931 3.962821
#> [16,] 4.347932 4.183283 4.121795
#> ACTGATGGTTCGCGAC-b01 ACTGATGTCACTCCTG-b01 ACTGCTCAGCTCCCAG-b01
#> [1,] 4.241818 4.202085 4.443118
#> [2,] 4.470909 4.209612 4.119382
#> [3,] 4.542727 4.113492 4.654494
#> [4,] 4.572727 4.117545 4.306882
#> [5,] 5.040909 4.984945 4.593399
#> [6,] 4.381818 3.693688 4.794242
#> [7,] 4.511818 4.831500 4.323034
#> [8,] 5.434545 4.415171 5.082865
#> [9,] 4.548182 4.195715 4.689607
#> [10,] 4.721818 3.965258 4.276685
#> [11,] 4.775455 4.357267 4.640449
#> [12,] 4.415455 4.070064 4.639045
#> [13,] 4.358182 4.023741 4.189607
#> [14,] 4.133636 4.873770 4.456461
#> [15,] 4.293636 3.459178 4.054775
#> [16,] 4.342727 3.995368 4.287921
#> ACTGCTCAGGTTCCTA-b01 ACTGCTCAGTGTACGG-b01 ACTGCTCGTGTCAATC-b01
#> [1,] 4.268966 4.361217 4.204032
#> [2,] 3.814943 3.358682 3.890654
#> [3,] 3.918391 3.873257 4.236408
#> [4,] 4.571264 4.494297 4.297495
#> [5,] 5.822989 5.083650 5.197923
#> [6,] 3.810345 3.637516 4.152718
#> [7,] 5.347126 4.812421 5.211362
#> [8,] 4.498851 4.455006 4.257789
#> [9,] 4.042529 3.977186 4.282224
#> [10,] 3.864368 4.045627 3.936469
#> [11,] 3.903448 4.230672 4.042761
#> [12,] 3.948276 3.868188 4.019548
#> [13,] 3.987356 4.031686 4.140501
#> [14,] 4.240230 4.277567 4.303604
#> [15,] 3.681609 3.608365 3.886378
#> [16,] 3.934483 3.925222 4.127062
#> ACTGCTCTCTAGCACA-b01 ACTGTCCAGGGTTCCC-b01 ACTGTCCAGTGATCGG-b01
#> [1,] 4.420173 4.356653 4.590055
#> [2,] 3.949876 4.108368 3.697392
#> [3,] 4.228342 4.086420 4.049121
#> [4,] 4.308168 4.098765 4.252274
#> [5,] 5.238243 4.585734 5.116434
#> [6,] 3.967822 4.325103 4.055185
#> [7,] 4.660891 4.336077 5.043056
#> [8,] 4.394802 5.016461 4.426925
#> [9,] 3.930074 4.787380 4.129776
#> [10,] 3.892327 4.754458 3.755003
#> [11,] 4.257426 4.307270 4.370528
#> [12,] 3.987005 4.251029 4.331110
#> [13,] 4.349629 4.477366 4.434809
#> [14,] 4.160891 4.024691 4.385082
#> [15,] 4.220916 4.032922 3.838084
#> [16,] 4.135520 4.305898 3.721649
#> ACTTTCACAACTGCGC-b01 ACTTTCACATTTCACT-b01 ACTTTCAGTACATCCA-b01
#> [1,] 4.201502 4.391975 4.440141
#> [2,] 3.941670 4.064043 3.951878
#> [3,] 4.154220 3.988426 3.740610
#> [4,] 4.306673 4.355710 4.382629
#> [5,] 5.073354 5.203704 4.909624
#> [6,] 4.224481 4.043981 3.586854
#> [7,] 4.955369 4.827160 4.323944
#> [8,] 4.543968 4.155864 4.429577
#> [9,] 4.360141 3.898148 4.046948
#> [10,] 4.042422 3.746142 4.030516
#> [11,] 4.133893 4.136574 3.771127
#> [12,] 4.003093 4.282407 3.923709
#> [13,] 4.167919 4.189815 4.325117
#> [14,] 4.547503 4.297840 4.188967
#> [15,] 3.863897 4.075617 3.915493
#> [16,] 4.012373 4.030864 3.658451
#> ACTTTCATCTTGTTTG-b01 AGAATAGAGTTTAGGA-b01 AGAATAGGTTCCAACA-b01
#> [1,] 4.179520 4.378160 4.679963
#> [2,] 4.078382 4.296259 3.830241
#> [3,] 4.128951 4.408493 4.010204
#> [4,] 4.284450 4.491405 4.262523
#> [5,] 4.460177 4.767442 5.120594
#> [6,] 4.347661 4.494439 3.836735
#> [7,] 4.547408 4.343782 4.612245
#> [8,] 4.987358 5.186047 4.226345
#> [9,] 4.443742 4.383215 3.952690
#> [10,] 4.328698 4.376138 3.830241
#> [11,] 4.025284 4.536906 3.796846
#> [12,] 4.388116 4.394338 3.954545
#> [13,] 4.436157 4.506572 4.131725
#> [14,] 4.623262 4.313448 4.282004
#> [15,] 4.275601 4.185035 4.068646
#> [16,] 4.525917 4.502528 3.953618
#> AGAATAGTCCAAGTAC-b01 AGAATAGTCTATCCTA-b01 AGACGTTCACCGCTAG-b01
#> [1,] 4.417526 4.338216 4.498294
#> [2,] 3.904639 4.252996 4.183163
#> [3,] 4.514175 4.703063 4.081911
#> [4,] 4.045103 4.312916 4.331058
#> [5,] 4.444588 4.354194 4.411832
#> [6,] 3.972938 4.170439 4.463026
#> [7,] 4.923969 4.259654 4.301479
#> [8,] 4.713918 5.390146 5.241183
#> [9,] 4.233247 4.509987 4.530148
#> [10,] 3.953608 4.125166 4.353811
#> [11,] 4.320876 4.532623 4.425484
#> [12,] 4.632732 4.083888 4.310580
#> [13,] 4.523196 4.312916 4.258248
#> [14,] 4.015464 4.085220 4.511945
#> [15,] 3.833763 4.110519 4.494881
#> [16,] 3.944588 3.940080 4.063709
#> AGACGTTTCTTAACCT-b01 AGAGCTTGTTCAGACT-b01 AGAGCTTTCCAACCAA-b01
#> [1,] 4.519036 4.721881 4.293233
#> [2,] 4.147208 3.926380 4.348684
#> [3,] 4.356599 4.430470 4.534774
#> [4,] 4.199239 4.074642 4.526316
#> [5,] 4.572335 4.440695 4.522556
#> [6,] 3.901015 3.893661 4.090226
#> [7,] 4.993655 4.429448 4.090226
#> [8,] 4.588832 4.740286 5.011278
#> [9,] 4.355330 4.019427 4.650376
#> [10,] 4.271574 3.897751 4.372180
#> [11,] 4.413706 4.609407 4.377820
#> [12,] 4.261421 4.346626 4.185150
#> [13,] 4.126904 4.327198 4.463346
#> [14,] 4.550761 3.939673 4.363722
#> [15,] 4.002538 3.904908 3.935150
#> [16,] 3.766497 4.233129 4.271617
#> AGAGCTTTCCAGGGCT-b01 AGATCTGGTGCCTGCA-b01 AGATCTGTCAAACAAG-b01
#> [1,] 4.390884 4.659705 4.353659
#> [2,] 4.245856 4.074939 4.055237
#> [3,] 4.320442 4.480344 3.934003
#> [4,] 4.029006 4.234644 4.002869
#> [5,] 4.382597 4.378378 5.260402
#> [6,] 3.982044 4.621622 3.556671
#> [7,] 4.390884 4.109337 4.761836
#> [8,] 4.936464 4.847666 4.607604
#> [9,] 4.273481 4.781327 4.382353
#> [10,] 4.055249 4.644963 3.803443
#> [11,] 3.944751 4.217445 4.351506
#> [12,] 4.388122 4.625307 4.027977
#> [13,] 4.388122 4.007371 4.236729
#> [14,] 4.299724 4.662162 4.705165
#> [15,] 4.564917 4.461916 3.598278
#> [16,] 4.251381 4.207617 4.248924
#> AGATCTGTCTGTCTCG-b01 AGATTGCCATGTAGTC-b01 AGCAGCCAGCAGACTG-b01
#> [1,] 4.314040 4.24750 4.231285
#> [2,] 4.088539 4.27625 3.968715
#> [3,] 4.260745 4.33750 4.229050
#> [4,] 4.485960 4.38375 4.465363
#> [5,] 4.777364 4.54375 5.010056
#> [6,] 3.859026 4.65125 4.049721
#> [7,] 4.553582 4.07875 5.063687
#> [8,] 4.422636 5.08875 4.391620
#> [9,] 4.237822 4.61375 4.268715
#> [10,] 4.234097 4.65750 4.139665
#> [11,] 4.296275 4.44750 4.268715
#> [12,] 4.169628 4.53500 4.218994
#> [13,] 4.311175 4.16500 4.205587
#> [14,] 4.517765 4.47125 4.581006
#> [15,] 4.065616 4.53125 3.876536
#> [16,] 4.040401 3.96625 3.921229
#> AGCATACCACTTGGAT-b01 AGCATACGTAGCGATG-b01 AGCCTAAAGGTTACCT-b01
#> [1,] 4.502703 4.722936 4.470021
#> [2,] 4.114865 4.002752 3.758030
#> [3,] 4.495946 4.427523 3.967880
#> [4,] 4.420270 4.496330 4.116702
#> [5,] 4.401351 4.878899 4.967880
#> [6,] 4.404054 4.016514 3.849036
#> [7,] 4.204054 4.308257 4.732334
#> [8,] 5.036486 4.537615 4.446467
#> [9,] 4.729730 3.869725 4.353319
#> [10,] 4.068919 3.866055 3.837259
#> [11,] 4.282432 4.122018 4.135974
#> [12,] 4.377027 3.953211 4.065310
#> [13,] 4.617568 4.001835 4.328694
#> [14,] 4.302703 4.088073 4.176660
#> [15,] 4.045946 4.293578 3.730193
#> [16,] 4.681081 4.498165 4.379015
#> AGCGGTCCATGGTAGG-b01 AGCGGTCGTGCAACTT-b01 AGCGTATGTAGCGTCC-b01
#> [1,] 4.350545 4.491285 4.337549
#> [2,] 3.832382 4.059913 4.362055
#> [3,] 4.051375 4.468410 4.561265
#> [4,] 4.276855 4.233115 4.192885
#> [5,] 5.366632 4.482571 4.656126
#> [6,] 4.101194 4.847495 4.358893
#> [7,] 5.034510 4.490196 4.520949
#> [8,] 4.494811 5.337691 4.977075
#> [9,] 4.241567 4.604575 4.441107
#> [10,] 3.995589 4.498911 4.286166
#> [11,] 4.142968 4.620915 4.358103
#> [12,] 4.018422 4.397603 4.444269
#> [13,] 4.200052 3.962963 4.132806
#> [14,] 4.532693 4.532680 4.301186
#> [15,] 3.867151 3.916122 4.151779
#> [16,] 3.978983 4.190632 4.456126
#> AGCGTCGTCTGGTTCC-b01 AGCTCCTCACATGACT-b01 AGCTCCTGTGTTCGAT-b01
#> [1,] 4.386351 4.535928 4.335821
#> [2,] 4.100395 3.826347 4.626866
#> [3,] 4.469261 4.121756 4.394030
#> [4,] 4.434292 4.212575 4.608955
#> [5,] 4.456289 5.097804 4.689552
#> [6,] 4.191201 4.077844 4.165672
#> [7,] 4.624365 4.797405 4.388060
#> [8,] 4.630006 4.460080 4.811940
#> [9,] 4.483926 4.252495 4.517910
#> [10,] 4.158488 3.920160 4.019403
#> [11,] 4.537507 4.217565 4.444776
#> [12,] 4.462493 3.922156 4.204478
#> [13,] 4.222222 4.305389 4.591045
#> [14,] 4.346306 4.151697 3.938806
#> [15,] 4.017484 4.238523 4.022388
#> [16,] 4.391991 4.200599 4.256716
#> AGCTCTCCAGCGATCC-b01 AGCTTGAGTTGCGTTA-b01 AGGCCACAGCTTTGGT-b01
#> [1,] 4.152080 4.688749 4.188418
#> [2,] 4.321377 4.305994 4.534140
#> [3,] 4.609756 4.278654 4.141746
#> [4,] 4.246772 4.532072 4.139153
#> [5,] 4.987088 4.651945 4.561798
#> [6,] 4.021521 4.138801 4.247191
#> [7,] 4.236729 4.444795 4.288678
#> [8,] 4.807747 4.707676 4.873812
#> [9,] 4.404591 4.369085 4.600691
#> [10,] 4.282640 4.066246 4.337079
#> [11,] 4.205165 4.214511 4.401037
#> [12,] 4.783357 4.323870 4.350908
#> [13,] 4.213773 4.603575 4.414002
#> [14,] 4.055954 4.215563 4.222126
#> [15,] 4.368723 4.085174 4.105445
#> [16,] 4.393113 4.685594 4.547105
#> AGGCCACAGTTAAGTG-b01 AGGCCACCATTGGCGC-b01 AGGCCGTAGAGCTGGT-b01
#> [1,] 4.282022 4.026347 4.252612
#> [2,] 4.326966 4.312575 4.345679
#> [3,] 4.544944 4.511377 4.152896
#> [4,] 4.300000 4.518563 4.285850
#> [5,] 4.832584 4.334132 4.849953
#> [6,] 4.103371 3.913772 4.354226
#> [7,] 4.231461 3.894611 4.352327
#> [8,] 4.728090 4.912575 4.668566
#> [9,] 4.349438 5.104192 4.503324
#> [10,] 4.244944 4.128144 4.144349
#> [11,] 4.008989 4.129341 4.359924
#> [12,] 4.275281 4.319760 4.288699
#> [13,] 4.312360 4.304192 4.830009
#> [14,] 4.044944 4.097006 4.291548
#> [15,] 4.094382 4.350898 4.151947
#> [16,] 4.252809 4.210778 4.065527
#> AGGCCGTAGAGCTTCT-b01 AGGCCGTCAAAGTCAA-b01 AGGCCGTTCGGCGCAT-b01
#> [1,] 4.421596 4.381959 4.491369
#> [2,] 4.107290 3.808247 4.407365
#> [3,] 4.500000 4.043299 4.418872
#> [4,] 4.202889 4.532474 4.520138
#> [5,] 4.737964 5.154639 4.660529
#> [6,] 4.030949 3.723196 4.214039
#> [7,] 4.391334 4.952062 4.158803
#> [8,] 4.860385 4.327835 5.197929
#> [9,] 4.544017 3.875773 4.454545
#> [10,] 4.337001 3.861856 4.367089
#> [11,] 4.428473 4.089691 4.352129
#> [12,] 4.289546 3.775773 4.187572
#> [13,] 4.590784 4.028866 4.565017
#> [14,] 4.238652 4.175773 4.187572
#> [15,] 4.315681 3.893299 4.231300
#> [16,] 4.132050 3.868557 4.017261
#> AGGGAGTTCCGATATG-b01 AGGGAGTTCCTCGCAT-b01 AGGGATGCATGCCACG-b01
#> [1,] 4.594355 4.566434 4.388383
#> [2,] 4.038710 4.762238 4.559226
#> [3,] 4.042742 4.012821 4.525057
#> [4,] 3.991935 4.438228 4.416856
#> [5,] 4.724194 4.208625 4.511390
#> [6,] 3.963710 4.305361 4.017084
#> [7,] 3.794355 4.449883 4.792711
#> [8,] 5.273387 5.207459 4.791572
#> [9,] 4.438710 4.066434 4.679954
#> [10,] 4.408065 4.285548 4.157175
#> [11,] 4.253226 4.583916 4.533030
#> [12,] 4.450000 4.365967 4.313212
#> [13,] 4.401613 4.404429 4.587699
#> [14,] 4.070161 4.434732 4.094533
#> [15,] 4.400000 4.145688 4.542141
#> [16,] 4.282258 3.822844 4.292711
#> AGGTCATCACTGTCGG-b01 AGGTCCGAGAGTACCG-b01 AGGTCCGTCATTGCCC-b01
#> [1,] 4.428919 4.420279 4.592119
#> [2,] 4.215067 4.151703 4.026624
#> [3,] 4.261847 4.267028 4.420660
#> [4,] 4.410085 4.247678 4.267306
#> [5,] 4.527947 4.595201 4.493078
#> [6,] 4.029162 3.978328 3.869010
#> [7,] 4.298906 4.502322 4.372737
#> [8,] 4.955650 4.336687 4.614483
#> [9,] 4.377278 4.175697 4.366347
#> [10,] 4.178007 4.154025 4.089457
#> [11,] 4.215674 4.476780 4.207668
#> [12,] 4.371203 4.278638 4.117146
#> [13,] 4.348117 4.167957 4.366347
#> [14,] 4.577764 3.985294 4.635783
#> [15,] 4.199271 4.300310 3.810437
#> [16,] 4.030377 3.969814 4.028754
#> AGTCTTTAGAACAATC-b01 AGTCTTTAGATCCCAT-b01 AGTGGGAGTACCGTAT-b01
#> [1,] 4.704410 4.628009 4.262278
#> [2,] 4.063170 4.335886 4.253918
#> [3,] 4.436234 4.330416 4.404911
#> [4,] 4.443385 4.092998 4.303030
#> [5,] 4.451728 4.693654 4.713166
#> [6,] 4.365912 4.270241 3.947231
#> [7,] 4.921335 4.266958 4.473354
#> [8,] 4.953516 4.700219 4.835946
#> [9,] 4.831943 4.742888 4.326541
#> [10,] 4.216925 4.168490 4.067921
#> [11,] 4.514899 4.335886 4.314525
#> [12,] 4.405244 4.481400 4.445664
#> [13,] 4.389750 4.307440 4.305643
#> [14,] 4.364720 4.157549 4.412748
#> [15,] 4.131108 4.044858 4.018286
#> [16,] 4.588796 4.250547 4.075235
#> AGTGGGAGTGTCGCTG-b01 AGTGGGAGTTCGAATC-b01 AGTGTCAGTTCTGGTA-b01
#> [1,] 4.319520 4.479478 4.340894
#> [2,] 4.505998 4.491604 3.891190
#> [3,] 4.285714 3.980410 4.068047
#> [4,] 4.699019 4.248134 4.406640
#> [5,] 4.630316 4.459888 5.100920
#> [6,] 4.324973 4.358209 4.142012
#> [7,] 4.280262 4.219216 4.782709
#> [8,] 4.822246 5.035448 4.312295
#> [9,] 4.691385 4.348881 4.290598
#> [10,] 4.455834 4.464552 4.065089
#> [11,] 4.473282 4.424440 4.090730
#> [12,] 4.675027 4.615672 4.169625
#> [13,] 4.245365 4.632463 4.224852
#> [14,] 4.388222 4.152985 4.348126
#> [15,] 4.425300 4.316231 3.914530
#> [16,] 4.218103 4.288246 4.140368
#> AGTTGGTTCAACACGT-b01 AGTTGGTTCTGCTGCT-b01 ATAACGCCAATGTTGC-b01
#> [1,] 4.616541 4.244199 4.605401
#> [2,] 4.285714 3.266298 3.864216
#> [3,] 4.169710 3.953591 4.257314
#> [4,] 4.102041 4.102762 4.624906
#> [5,] 4.648765 5.169061 4.777944
#> [6,] 4.094522 3.764641 3.720180
#> [7,] 4.824919 5.325967 4.528132
#> [8,] 4.744361 4.188950 4.621155
#> [9,] 4.387755 4.150276 3.942986
#> [10,] 3.741139 3.574586 3.906227
#> [11,] 4.237379 3.961326 3.740435
#> [12,] 4.248120 3.974586 4.222056
#> [13,] 4.258861 4.334807 4.076519
#> [14,] 4.146079 4.587845 4.125281
#> [15,] 4.078410 3.721547 4.266317
#> [16,] 4.301826 3.977901 4.075019
#> ATAAGAGAGCTACCTA-b01 ATAAGAGGTAAGTTCC-b01 ATAGACCAGAAGATTC-b01
#> [1,] 4.462469 4.478144 4.298205
#> [2,] 3.880605 4.109012 4.245902
#> [3,] 4.225189 4.291419 4.334895
#> [4,] 4.308816 4.419320 4.698673
#> [5,] 5.160705 4.780356 4.621390
#> [6,] 4.078086 4.335132 4.432475
#> [7,] 4.776322 4.297356 4.085090
#> [8,] 4.508816 4.822990 5.226386
#> [9,] 4.008060 4.199676 4.533177
#> [10,] 3.961713 4.228818 4.615144
#> [11,] 4.229723 4.441446 4.744731
#> [12,] 4.081612 4.254722 4.548790
#> [13,] 4.304282 4.442526 4.316159
#> [14,] 4.289673 4.193740 4.329430
#> [15,] 3.859446 3.997841 4.232631
#> [16,] 3.903778 4.062062 4.302108
#> ATAGACCCAGCTCGAC-b01 ATCACGAGTACAGTTC-b01 ATCACGAGTAGCCTCG-b01
#> [1,] 4.654738 4.486017 4.376780
#> [2,] 4.156101 3.771456 3.993428
#> [3,] 4.052147 4.085824 4.109529
#> [4,] 4.267553 4.292189 4.207010
#> [5,] 4.512270 5.155256 5.061884
#> [6,] 4.288003 3.805207 3.965498
#> [7,] 4.143831 5.204436 5.170865
#> [8,] 4.868439 4.677917 4.306681
#> [9,] 4.509543 4.277724 4.232749
#> [10,] 4.221200 3.981678 3.803943
#> [11,] 4.205521 4.138862 4.145126
#> [12,] 4.321745 4.268081 4.076670
#> [13,] 4.558282 4.146577 4.385542
#> [14,] 4.338105 4.407907 4.363636
#> [15,] 4.107703 3.972035 3.924973
#> [16,] 4.418200 4.075217 3.997809
#> ATCACGATCCGAATGT-b01 ATCATCTCAAGAAGAG-b01 ATCTGCCCAATAGAGT-b01
#> [1,] 4.315575 4.260718 4.371005
#> [2,] 4.047174 4.388181 4.045207
#> [3,] 4.165514 4.409038 4.363991
#> [4,] 4.197641 4.539977 3.983632
#> [5,] 5.250102 4.316338 4.664069
#> [6,] 3.873932 4.221321 4.176929
#> [7,] 5.017487 3.951333 4.303196
#> [8,] 4.561204 4.578216 4.336711
#> [9,] 3.984953 4.645423 4.321122
#> [10,] 4.070760 4.207416 4.213562
#> [11,] 4.226515 4.217845 4.053001
#> [12,] 4.020740 4.405562 4.280592
#> [13,] 4.047987 4.332561 4.453624
#> [14,] 4.354616 4.392816 4.295401
#> [15,] 4.059374 4.165701 4.522993
#> [16,] 4.110614 4.549247 4.351520
#> ATGAGGGAGGCAGTCA-b01 ATGAGGGGTATCACCA-b01 ATGAGGGTCGGCGGTT-b01
#> [1,] 4.018018 4.231879 4.156383
#> [2,] 4.374775 4.442294 4.053191
#> [3,] 4.239640 4.351513 4.234043
#> [4,] 4.336937 4.449683 4.364894
#> [5,] 5.138288 4.878255 4.911702
#> [6,] 4.156757 4.036946 4.548936
#> [7,] 4.898198 4.681210 4.232979
#> [8,] 4.662162 4.646376 5.313830
#> [9,] 4.252703 4.276214 4.406383
#> [10,] 4.036036 4.318790 4.615957
#> [11,] 4.344144 4.439127 4.873404
#> [12,] 3.988739 4.334624 4.413830
#> [13,] 4.217568 3.948276 4.412766
#> [14,] 4.650901 4.559465 4.539362
#> [15,] 3.664865 3.894089 4.463830
#> [16,] 4.226577 3.992963 4.524468
#> ATGAGGGTCTGCTTGC-b01 ATGCGATAGTTCGATC-b01 ATGCGATCACCAGGCT-b01
#> [1,] 4.129448 4.220220 4.437434
#> [2,] 4.141014 4.313313 3.819528
#> [3,] 4.008007 4.232232 4.114205
#> [4,] 4.474199 3.992993 4.316884
#> [5,] 5.196174 4.915916 5.227000
#> [6,] 4.067171 4.368368 3.980261
#> [7,] 4.930160 4.289289 4.794854
#> [8,] 4.105872 4.795796 4.281988
#> [9,] 4.139235 4.633634 4.069792
#> [10,] 4.010231 4.235235 3.995065
#> [11,] 4.140125 4.401401 4.088474
#> [12,] 4.112989 4.195195 3.749383
#> [13,] 4.387011 4.587588 4.212548
#> [14,] 4.541815 4.500501 4.428269
#> [15,] 3.918149 3.908909 3.986253
#> [16,] 4.093416 4.235235 3.956644
#> ATGGGAGGTCTGATCA-b01 ATTACTCGTGACCAAG-b01 ATTACTCGTTGGAGGT-b01
#> [1,] 4.070748 4.414680 4.202740
#> [2,] 4.571429 4.068381 4.450685
#> [3,] 4.371429 3.978670 4.352055
#> [4,] 4.812245 4.271016 4.175342
#> [5,] 4.421769 4.720201 4.624658
#> [6,] 3.831293 3.754078 4.269863
#> [7,] 4.235374 4.483689 4.608219
#> [8,] 5.029932 5.019448 4.860274
#> [9,] 4.878912 4.383312 4.310959
#> [10,] 4.329252 3.747804 4.505479
#> [11,] 4.220408 4.258469 4.510959
#> [12,] 4.402721 3.943538 4.808219
#> [13,] 4.103401 4.297365 4.287671
#> [14,] 4.666667 4.549561 4.439726
#> [15,] 4.278912 3.861982 4.568493
#> [16,] 3.959184 4.171895 4.231507
#> ATTATCCGTAGCGTCC-b01 ATTATCCTCAGGCAAG-b01 ATTGGTGTCCGAGCCA-b01
#> [1,] 4.688941 4.159722 4.263330
#> [2,] 4.031059 4.439815 4.579978
#> [3,] 4.277176 4.462963 4.356910
#> [4,] 4.431529 4.383102 4.321001
#> [5,] 4.806118 4.576389 4.383025
#> [6,] 3.875765 3.783565 3.804135
#> [7,] 4.564235 4.349537 3.967356
#> [8,] 4.660235 4.962963 5.421110
#> [9,] 4.150118 4.486111 4.505985
#> [10,] 4.056471 4.269676 4.175190
#> [11,] 4.092235 4.608796 4.341676
#> [12,] 4.008941 4.622685 4.144723
#> [13,] 4.252235 4.281250 4.768226
#> [14,] 4.132706 4.483796 4.525571
#> [15,] 3.956235 4.401620 4.020675
#> [16,] 3.950588 4.137731 4.229597
#> ATTTCTGAGAATTCCC-b01 CAACCAAAGGACGAAA-b01 CAACCTCAGCCCAGCT-b01
#> [1,] 4.464876 4.461538 4.832386
#> [2,] 3.972107 4.095442 3.428977
#> [3,] 3.934917 3.797721 3.622159
#> [4,] 4.300620 4.370370 4.382102
#> [5,] 5.305785 4.682336 4.754261
#> [6,] 4.131198 3.484330 3.718750
#> [7,] 5.075413 4.678063 4.326705
#> [8,] 4.496901 4.596866 4.897727
#> [9,] 3.947314 4.289174 4.109375
#> [10,] 3.827479 3.773504 3.677557
#> [11,] 3.938017 4.148148 3.968750
#> [12,] 3.844008 3.941595 3.723011
#> [13,] 4.332645 4.346154 4.400568
#> [14,] 4.370868 4.507123 4.240057
#> [15,] 3.875000 3.665242 3.872159
#> [16,] 4.010331 4.257835 3.819602
#> CAACCTCAGGAGTCTG-b01 CAACCTCGTGCTAGCC-b01 CAACCTCTCACGATGT-b01
#> [1,] 4.509942 4.226355 4.643
#> [2,] 4.385965 4.005313 4.271
#> [3,] 4.215205 4.568544 4.324
#> [4,] 4.343860 4.277365 4.322
#> [5,] 4.499415 4.590861 4.902
#> [6,] 4.591813 4.041445 4.192
#> [7,] 4.178947 4.441020 3.953
#> [8,] 4.905263 4.553666 5.185
#> [9,] 4.604678 4.488842 4.620
#> [10,] 4.315789 4.310308 3.769
#> [11,] 4.281871 4.362380 4.414
#> [12,] 4.232749 4.308183 4.346
#> [13,] 4.433918 4.290117 4.587
#> [14,] 4.224561 4.282678 4.265
#> [15,] 3.837427 4.038257 4.175
#> [16,] 4.288889 4.313496 4.546
#> CAACTAGCACGAAGCA-b01 CAACTAGGTACCATCA-b01 CAAGAAACATGCCTAA-b01
#> [1,] 4.577661 4.253968 4.614865
#> [2,] 3.815009 3.807172 4.124324
#> [3,] 4.206515 4.125808 4.312162
#> [4,] 4.372309 4.222222 4.445946
#> [5,] 5.191390 5.347443 4.562162
#> [6,] 3.830716 4.115226 4.363514
#> [7,] 4.922048 4.995297 4.550000
#> [8,] 4.478185 4.221634 5.004054
#> [9,] 4.261198 4.342740 4.352703
#> [10,] 3.890634 4.090535 4.287838
#> [11,] 4.011635 4.099353 4.322973
#> [12,] 3.971495 3.964139 4.190541
#> [13,] 4.165794 4.155791 4.850000
#> [14,] 4.330425 4.559671 4.258108
#> [15,] 4.026178 3.941799 4.487838
#> [16,] 3.934846 4.119929 4.533784
#> CAAGAAAGTATGGTTC-b01 CAAGAAATCACGATGT-b01 CAAGATCAGAGGTACC-b01
#> [1,] 4.763387 4.470968 4.273531
#> [2,] 3.910336 3.739355 3.681617
#> [3,] 4.032379 4.238710 3.970941
#> [4,] 4.216687 4.483871 4.360708
#> [5,] 5.107098 4.677419 5.277322
#> [6,] 4.031133 3.596129 3.885028
#> [7,] 4.494396 4.531613 4.965256
#> [8,] 4.478207 4.730323 4.370815
#> [9,] 4.094645 4.202581 4.384081
#> [10,] 4.042341 3.966452 4.110550
#> [11,] 4.021171 4.139355 4.027164
#> [12,] 4.259029 3.998710 4.086545
#> [13,] 4.359900 4.019355 4.132028
#> [14,] 4.219178 4.529032 4.530006
#> [15,] 4.028643 3.983226 3.747947
#> [16,] 3.789539 3.925161 4.183828
#> CAAGGCCGTCTGATCA-b01 CAAGGCCGTTCTGAAC-b01 CAAGTTGCATTTCAGG-b01
#> [1,] 4.352391 4.133333 4.508375
#> [2,] 4.305613 4.193464 4.351290
#> [3,] 4.528067 4.424837 4.404708
#> [4,] 4.248441 4.508497 4.243096
#> [5,] 4.320166 4.552941 4.474876
#> [6,] 3.899168 4.422222 4.448167
#> [7,] 4.120582 4.394771 4.318244
#> [8,] 4.933472 4.836601 4.998642
#> [9,] 4.619543 4.657516 4.689000
#> [10,] 4.178794 4.515033 4.251698
#> [11,] 4.345114 4.368627 4.289724
#> [12,] 4.276507 4.788235 4.357628
#> [13,] 3.994802 4.384314 4.532368
#> [14,] 4.430353 4.406536 4.449977
#> [15,] 4.010395 4.377778 4.167044
#> [16,] 4.089397 4.509804 4.582617
#> CACACAATCCAATGGT-b01 CACACAATCGTTGCCT-b01 CACACCTCAGAGCCAA-b01
#> [1,] 4.580392 4.431418 4.274055
#> [2,] 3.976471 4.032950 4.575601
#> [3,] 3.933333 4.345594 4.166667
#> [4,] 4.345098 4.698851 4.485395
#> [5,] 4.928105 5.041379 4.365979
#> [6,] 3.712418 4.059770 4.102234
#> [7,] 4.922876 4.553257 4.349656
#> [8,] 4.525490 4.796169 4.520619
#> [9,] 4.223529 4.331801 4.642612
#> [10,] 3.955556 4.038314 4.990550
#> [11,] 3.802614 4.284291 4.260309
#> [12,] 4.347712 4.189272 4.158076
#> [13,] 4.334641 4.257471 4.679553
#> [14,] 4.241830 4.462069 4.221649
#> [15,] 3.555556 4.008429 4.710481
#> [16,] 3.917647 4.169349 4.104811
#> CACACTCCACGGTGTC-b01 CACAGGCGTGAGGGTT-b01 CACAGGCTCATGTCCC-b01
#> [1,] 4.603037 4.612621 4.019157
#> [2,] 4.706074 4.405784 3.984674
#> [3,] 4.305857 4.255039 4.070243
#> [4,] 4.367679 4.388256 4.476373
#> [5,] 4.382863 4.542507 4.522350
#> [6,] 4.571584 4.390009 4.602810
#> [7,] 4.075922 4.234005 4.376756
#> [8,] 4.694143 4.609115 5.306513
#> [9,] 4.065076 4.296231 4.418902
#> [10,] 4.515184 4.411043 4.679438
#> [11,] 4.574837 4.251534 4.440613
#> [12,] 4.328633 4.374233 4.486590
#> [13,] 4.464208 4.247152 4.356322
#> [14,] 4.317787 4.315513 4.616858
#> [15,] 3.968547 3.899211 4.619413
#> [16,] 4.215835 3.992989 4.252874
#> CACAGTAAGAAGGTGA-b01 CACAGTAGTTTAAGCC-b01 CACATAGAGGATCGCA-b01
#> [1,] 4.352033 4.251825 4.688615
#> [2,] 4.289157 4.055961 4.713306
#> [3,] 4.191642 4.458637 4.251029
#> [4,] 4.320030 4.323601 4.444444
#> [5,] 4.585467 4.701946 4.408779
#> [6,] 4.400226 3.939173 4.489712
#> [7,] 4.027861 4.399027 4.229081
#> [8,] 4.972892 4.826034 5.212620
#> [9,] 4.661145 4.304136 4.303155
#> [10,] 4.360316 4.205596 4.485597
#> [11,] 4.282380 4.083942 4.312757
#> [12,] 4.385542 4.392944 4.599451
#> [13,] 4.276732 4.262774 4.426612
#> [14,] 4.438253 4.108273 4.048011
#> [15,] 4.213479 4.315085 4.068587
#> [16,] 4.282003 4.250608 3.935528
#> CACATAGCACTGTCGG-b01 CACATAGTCTTGTACT-b01 CACATTTAGACGACGT-b01
#> [1,] 4.399423 3.868687 4.680198
#> [2,] 4.148219 4.732026 3.689109
#> [3,] 4.522618 4.035651 3.901980
#> [4,] 4.470645 3.844920 4.138614
#> [5,] 4.487969 5.142602 4.888119
#> [6,] 4.466795 3.969103 4.297030
#> [7,] 4.426372 4.655971 4.843564
#> [8,] 4.778633 5.223411 4.344554
#> [9,] 4.577478 4.142008 4.328713
#> [10,] 4.237729 4.058229 4.051485
#> [11,] 4.431184 4.466429 4.351485
#> [12,] 4.663138 3.752822 4.396040
#> [13,] 4.246391 4.172906 4.526733
#> [14,] 4.151107 4.713012 4.320792
#> [15,] 4.249278 3.911468 3.920792
#> [16,] 3.987488 3.961378 3.945545
#> CACCACTCACAGTCGC-b01 CACCACTCAGCTTAAC-b01 CACCACTTCTTGAGGT-b01
#> [1,] 4.132609 4.305768 4.478442
#> [2,] 4.178261 4.259903 4.059805
#> [3,] 4.024845 4.487144 4.514604
#> [4,] 4.308075 4.422516 4.282337
#> [5,] 5.255280 4.838777 4.404729
#> [6,] 3.990373 4.016678 4.452017
#> [7,] 4.917702 4.530229 4.356050
#> [8,] 4.410559 4.783183 5.312935
#> [9,] 4.036335 4.214038 4.621697
#> [10,] 4.070497 3.936762 4.507650
#> [11,] 4.319876 4.186935 4.479833
#> [12,] 3.980124 4.360667 4.385257
#> [13,] 4.180745 4.538568 4.246175
#> [14,] 4.457453 4.214732 4.233658
#> [15,] 3.824224 3.929117 4.339360
#> [16,] 4.093168 4.084086 4.563282
#> CACCAGGGTAAACCTC-b01 CACCAGGGTCAAAGAT-b01 CACTCCACAGATCTGT-b01
#> [1,] 4.342012 4.394069 4.203837
#> [2,] 4.347929 4.239953 4.321343
#> [3,] 4.573964 3.989856 4.175060
#> [4,] 4.360947 4.198595 3.979616
#> [5,] 4.542012 4.523605 4.514388
#> [6,] 4.372781 4.156847 4.231415
#> [7,] 4.589349 4.220835 4.229017
#> [8,] 5.004734 5.014436 5.130695
#> [9,] 4.872189 4.595396 5.057554
#> [10,] 4.872189 4.259462 4.453237
#> [11,] 4.487574 4.506828 4.431655
#> [12,] 4.382249 4.209130 4.503597
#> [13,] 4.408284 4.564963 4.244604
#> [14,] 4.466272 4.310964 4.241007
#> [15,] 4.743195 4.142411 4.573141
#> [16,] 4.409467 4.481077 4.453237
#> CAGAATCAGCGATAGC-b01 CAGAGAGTCCTTCAAT-b01 CAGATCAGTGGAAAGA-b01
#> [1,] 4.385143 4.426 4.383041
#> [2,] 3.961143 4.375 3.833333
#> [3,] 4.022857 4.398 4.191033
#> [4,] 4.149714 4.335 4.452242
#> [5,] 5.033143 4.391 5.145224
#> [6,] 3.781714 4.144 4.056530
#> [7,] 4.520000 4.471 4.969786
#> [8,] 4.548571 5.180 4.340156
#> [9,] 4.425143 4.732 4.184211
#> [10,] 3.811429 4.115 3.884990
#> [11,] 3.971429 4.470 4.017544
#> [12,] 4.009143 4.326 4.054581
#> [13,] 4.276571 4.608 4.274854
#> [14,] 4.106286 4.129 4.407407
#> [15,] 3.779429 3.856 3.972710
#> [16,] 4.092571 4.508 3.839181
#> CAGCAGCAGAGGGATA-b01 CAGCAGCTCCATGAGT-b01 CAGCATAGTCTCTTTA-b01
#> [1,] 4.129739 4.502623 4.454318
#> [2,] 4.268745 3.830010 3.652065
#> [3,] 4.358045 4.168940 4.026283
#> [4,] 4.303286 4.438615 4.359199
#> [5,] 4.783488 5.035677 4.813517
#> [6,] 4.115417 3.926548 3.779725
#> [7,] 4.333614 4.396642 4.618273
#> [8,] 4.780960 4.526758 4.266583
#> [9,] 4.285594 3.861490 3.959950
#> [10,] 4.163437 4.286464 4.012516
#> [11,] 4.167650 4.107030 4.115144
#> [12,] 4.032013 4.089192 4.310388
#> [13,] 4.176917 4.034627 4.760951
#> [14,] 3.983993 4.139559 4.002503
#> [15,] 4.232519 4.110178 4.269086
#> [16,] 4.190396 4.327387 4.147685
#> CAGCGACAGACACTAA-b01 CAGCGACGTCGTCTTC-b01 CAGCGACTCATTCACT-b01
#> [1,] 4.266151 4.369077 4.562023
#> [2,] 4.322025 4.231920 4.591603
#> [3,] 4.416313 4.274314 4.519084
#> [4,] 4.415814 4.301746 4.472328
#> [5,] 5.036667 4.613466 4.515267
#> [6,] 4.031928 4.089776 4.231870
#> [7,] 4.970816 4.264339 4.306298
#> [8,] 4.399601 4.958853 4.831107
#> [9,] 4.252681 4.618454 4.820611
#> [10,] 4.052632 4.697007 4.253817
#> [11,] 4.229733 4.137157 4.187023
#> [12,] 4.127962 4.599751 4.302481
#> [13,] 4.150412 4.692020 4.439885
#> [14,] 4.662010 4.078554 4.208015
#> [15,] 3.916937 4.913965 4.312977
#> [16,] 4.155650 4.088529 4.536260
#> CAGCTAAGTTGGTGGA-b01 CAGCTGGCACCTCGTT-b01 CAGTAACCAGTATGCT-b01
#> [1,] 4.493094 4.382576 4.614486
#> [2,] 4.064917 4.062290 3.690421
#> [3,] 4.487569 4.187710 4.035047
#> [4,] 4.411602 4.258838 4.039720
#> [5,] 4.581492 4.944024 4.905374
#> [6,] 4.269337 3.960438 3.860981
#> [7,] 4.256906 4.939394 4.622664
#> [8,] 4.726519 4.759259 4.221963
#> [9,] 4.424033 4.333333 4.120327
#> [10,] 4.323204 3.951599 3.808411
#> [11,] 4.091160 4.312710 4.039720
#> [12,] 4.073204 3.891835 4.136682
#> [13,] 4.006906 4.193603 4.564252
#> [14,] 4.320442 4.691919 4.033879
#> [15,] 4.113260 3.735269 3.844626
#> [16,] 4.324586 4.007997 3.830607
#> CAGTAACTCACCCTCA-b01 CATATGGAGGTAAACT-b01 CATATGGAGTAACCCT-b01
#> [1,] 4.467497 4.465187 4.164023
#> [2,] 4.468880 4.228052 4.143909
#> [3,] 4.556017 4.327952 4.110482
#> [4,] 4.190871 4.482341 4.447309
#> [5,] 4.360996 4.772957 5.375637
#> [6,] 4.260028 4.041372 3.873088
#> [7,] 4.428769 4.549950 5.104816
#> [8,] 4.979253 4.754793 4.503966
#> [9,] 4.897649 4.190716 4.235977
#> [10,] 4.293223 3.872856 3.999717
#> [11,] 4.196404 4.258325 4.334844
#> [12,] 4.374827 4.171544 3.965722
#> [13,] 4.515906 4.534813 4.259490
#> [14,] 4.247580 4.089808 4.567422
#> [15,] 4.048409 3.990918 3.699717
#> [16,] 4.529737 4.098890 3.852125
#> CATATTCGTATCACCA-b01 CATATTCGTCCAAGTT-b01 CATCAAGGTAGCTAAA-b01
#> [1,] 4.385209 4.181499 4.556878
#> [2,] 3.859486 4.292740 4.275132
#> [3,] 4.181994 4.326698 4.042328
#> [4,] 4.377492 4.348946 4.079365
#> [5,] 5.146945 4.290398 4.332011
#> [6,] 4.259164 4.091335 4.800265
#> [7,] 4.590997 4.277518 3.843915
#> [8,] 4.587781 4.933255 5.041005
#> [9,] 4.174277 4.247073 4.432540
#> [10,] 4.273633 4.083138 3.951058
#> [11,] 4.282315 4.373536 4.222222
#> [12,] 4.058521 4.464871 3.952381
#> [13,] 4.351447 4.495316 4.580688
#> [14,] 4.356592 4.088993 4.673280
#> [15,] 4.195177 4.110070 3.890212
#> [16,] 4.169775 4.467213 4.629630
#> CATCCACCAGCCACCA-b01 CATCCACGTCTAGGTT-b01 CATCGAAAGGGTTCCC-b01
#> [1,] 4.409850 4.062678 4.267588
#> [2,] 3.941953 4.179487 4.138191
#> [3,] 4.434477 4.106838 4.522613
#> [4,] 4.164468 4.575499 4.727387
#> [5,] 4.719437 4.819088 4.606784
#> [6,] 4.972735 4.007123 4.152010
#> [7,] 4.484609 4.239316 4.178392
#> [8,] 5.070361 5.243590 5.731156
#> [9,] 4.654354 4.584046 4.920854
#> [10,] 4.247142 4.282051 4.241206
#> [11,] 4.738786 4.266382 4.275126
#> [12,] 4.508355 4.509972 3.913317
#> [13,] 3.944591 4.512821 3.880653
#> [14,] 4.313105 4.519943 4.346734
#> [15,] 4.305189 3.950142 4.684673
#> [16,] 4.320141 4.358974 4.623116
#> CATCGAAGTCCAAGTT-b01 CATCGAATCATGTCCC-b01 CATCGGGGTATGAATG-b01
#> [1,] 4.332521 4.273278 4.359707
#> [2,] 4.521315 4.037093 4.167553
#> [3,] 4.255786 4.154807 4.078457
#> [4,] 4.341048 4.342922 4.107048
#> [5,] 4.277710 5.066616 4.900266
#> [6,] 3.756395 4.030659 3.816489
#> [7,] 4.107186 4.628690 4.900931
#> [8,] 4.923264 4.478425 4.615027
#> [9,] 4.775883 4.371688 4.030585
#> [10,] 4.386114 4.031037 3.980053
#> [11,] 4.056029 4.230886 4.570479
#> [12,] 4.019488 4.118849 4.113032
#> [13,] 4.772229 4.269493 4.277926
#> [14,] 4.440926 4.380015 4.837766
#> [15,] 4.293544 4.085920 3.822473
#> [16,] 3.908648 3.905753 3.918883
#> CATGACAAGTTAACGA-b01 CATGACAGTAAGTGTA-b01 CATGCCTCACAGTCGC-b01
#> [1,] 4.256748 4.198482 4.344347
#> [2,] 4.311990 4.045011 4.662996
#> [3,] 4.331450 4.290672 4.314978
#> [4,] 4.263653 4.527657 4.322320
#> [5,] 5.173886 5.193601 4.362702
#> [6,] 4.072819 3.951735 4.388399
#> [7,] 4.677338 5.180043 4.456681
#> [8,] 4.507219 4.303145 5.089574
#> [9,] 4.202762 3.986443 4.582966
#> [10,] 4.146893 3.930043 4.112335
#> [11,] 4.345888 4.268438 4.293686
#> [12,] 3.944758 4.067787 4.474302
#> [13,] 4.197112 4.245662 4.442731
#> [14,] 4.453861 4.264642 4.370044
#> [15,] 3.940364 3.958785 4.350954
#> [16,] 4.048964 4.078633 4.243025
#> CATGGCGAGAATTGTG-b01 CATTATCCACGTCTCT-b01 CATTATCTCCGCGGTA-b01
#> [1,] 4.462466 4.151348 4.547358
#> [2,] 4.169571 4.250864 4.148554
#> [3,] 4.372654 4.218383 4.366899
#> [4,] 4.339812 4.366275 4.655035
#> [5,] 4.847855 4.686247 4.255234
#> [6,] 3.975201 3.876987 4.101695
#> [7,] 4.716488 4.561161 4.371884
#> [8,] 4.394772 4.676572 4.798604
#> [9,] 4.268097 4.333103 5.365902
#> [10,] 4.025469 4.219765 5.064806
#> [11,] 4.187668 4.311679 4.146560
#> [12,] 4.205764 4.252246 4.258225
#> [13,] 3.969169 4.026261 4.314058
#> [14,] 4.361260 4.480304 4.516451
#> [15,] 3.998660 4.099516 4.885344
#> [16,] 4.048257 3.911541 3.997009
#> CCAATCCTCCAGAAGG-b01 CCACCTAAGCTCTCGG-b01 CCACCTAAGTGAAGAG-b01
#> [1,] 4.330171 4.394839 4.539615
#> [2,] 4.051233 4.094194 3.747323
#> [3,] 4.078273 4.410323 3.970021
#> [4,] 4.415560 3.957419 4.100642
#> [5,] 4.999051 4.143226 4.756959
#> [6,] 4.041271 4.263226 3.901499
#> [7,] 4.729602 4.027097 4.600642
#> [8,] 4.500474 5.405161 4.516060
#> [9,] 4.237666 4.614194 4.070664
#> [10,] 3.904649 4.207742 3.569593
#> [11,] 4.236243 4.421935 3.571734
#> [12,] 4.100569 4.849032 3.987152
#> [13,] 4.155598 4.183226 4.261242
#> [14,] 4.555028 4.421935 4.377944
#> [15,] 3.833491 4.340645 4.053533
#> [16,] 3.929317 4.585806 4.092077
#> CCACCTACAGGTGCCT-b01 CCACCTATCAGCTGGC-b01 CCACCTATCCTGTACC-b01
#> [1,] 4.407316 4.389701 4.535322
#> [2,] 3.997534 3.709812 4.138148
#> [3,] 4.166872 3.946416 4.276295
#> [4,] 4.524866 4.395964 4.723705
#> [5,] 4.932594 5.084203 5.029042
#> [6,] 3.959309 3.906054 4.069074
#> [7,] 4.547472 5.172582 4.522763
#> [8,] 4.681463 4.578984 4.514914
#> [9,] 4.279079 4.124565 4.115385
#> [10,] 4.104398 3.938761 3.828885
#> [11,] 4.119194 4.007655 3.981162
#> [12,] 4.265105 3.973556 4.208791
#> [13,] 4.038224 4.023660 4.041601
#> [14,] 4.375668 4.221294 4.091052
#> [15,] 4.118372 3.953375 3.933281
#> [16,] 4.196876 3.814196 3.950549
#> CCAGCGAAGGAATGGA-b01 CCAGCGACATGTCGAT-b01 CCATGTCAGCAAATCA-b01
#> [1,] 4.335432 4.314526 4.489177
#> [2,] 4.182554 4.667467 3.935931
#> [3,] 4.404676 4.827131 3.872727
#> [4,] 4.471223 4.558223 4.315152
#> [5,] 4.690647 4.282113 4.858009
#> [6,] 4.093525 3.865546 4.114286
#> [7,] 4.009892 4.163265 4.716883
#> [8,] 5.013489 5.309724 4.557576
#> [9,] 4.736511 4.733493 4.073593
#> [10,] 4.364209 4.099640 3.805195
#> [11,] 4.332734 4.468187 3.782684
#> [12,] 4.312950 4.513806 4.270996
#> [13,] 4.453237 4.440576 4.187879
#> [14,] 4.447842 4.164466 4.322944
#> [15,] 4.290468 4.151261 3.993074
#> [16,] 4.339928 4.459784 4.032900
#> CCATGTCTCACTTATC-b01 CCCAATCAGCGTGTCC-b01 CCCAGTTCACCCATGG-b01
#> [1,] 4.061429 4.715017 4.844523
#> [2,] 3.978736 3.915529 4.391721
#> [3,] 4.090372 4.313140 4.361434
#> [4,] 4.201418 4.436007 4.205452
#> [5,] 5.247490 4.855802 4.403332
#> [6,] 3.890727 3.954778 4.469965
#> [7,] 5.199646 4.470990 4.308430
#> [8,] 4.539870 4.397611 5.023221
#> [9,] 4.334318 4.058874 4.654720
#> [10,] 4.079149 3.709044 4.228672
#> [11,] 4.523331 4.383959 4.274609
#> [12,] 4.171294 3.996587 4.463907
#> [13,] 4.204371 4.133959 4.305906
#> [14,] 4.708210 4.068259 4.282686
#> [15,] 3.777909 3.964164 4.105502
#> [16,] 4.131128 4.046075 4.558809
#> CCCATACCACCAGCAC-b01 CCCATACCACGGCCAT-b01 CCCATACGTTACGTCA-b01
#> [1,] 4.787178 4.587807 4.497415
#> [2,] 3.795464 4.303913 3.658738
#> [3,] 3.883123 4.421292 4.200620
#> [4,] 4.269952 4.339399 4.036194
#> [5,] 4.934584 4.452229 4.899690
#> [6,] 3.909725 4.537762 3.872802
#> [7,] 4.284780 4.016379 4.849018
#> [8,] 4.568687 4.986351 4.594623
#> [9,] 4.448321 4.626934 4.247156
#> [10,] 3.911034 4.379436 3.775595
#> [11,] 3.964239 4.723385 4.057911
#> [12,] 3.990406 4.467698 4.253361
#> [13,] 4.569996 4.329390 4.237849
#> [14,] 4.443960 4.131938 4.456050
#> [15,] 3.855212 4.235669 4.235781
#> [16,] 3.993022 4.363057 4.072389
#> CCCTCCTCAATCAGAA-b01 CCGGGATGTAGCACGA-b01 CCGTTCATCATCTGCC-b01
#> [1,] 4.180985 4.458378 4.166048
#> [2,] 4.216781 3.472432 4.454545
#> [3,] 4.361970 4.052973 4.525974
#> [4,] 4.507159 4.223784 4.393321
#> [5,] 5.020905 4.872432 4.335807
#> [6,] 4.008591 3.957838 4.190167
#> [7,] 4.742268 4.932973 4.320037
#> [8,] 4.572451 4.492973 4.777365
#> [9,] 4.324742 4.331892 4.497217
#> [10,] 4.030069 3.873514 4.358998
#> [11,] 4.493986 4.296216 4.242115
#> [12,] 4.145475 4.265946 4.380334
#> [13,] 4.060710 4.212973 4.333952
#> [14,] 4.612829 4.420541 4.125232
#> [15,] 3.887457 3.791351 4.323748
#> [16,] 4.214777 3.876757 4.351577
#> CCGTTCATCTACTTAC-b01 CCTAAAGAGGACGAAA-b01 CCTACACCACGGATAG-b01
#> [1,] 4.317004 4.431150 4.434954
#> [2,] 3.982996 4.099536 3.996058
#> [3,] 4.157490 4.201650 4.090670
#> [4,] 4.249798 4.522950 3.906702
#> [5,] 4.838866 5.118618 4.721419
#> [6,] 3.926316 4.092316 4.208936
#> [7,] 4.498381 4.800928 4.691196
#> [8,] 4.755870 4.567818 4.533509
#> [9,] 4.255466 4.437339 4.262812
#> [10,] 3.890283 3.933471 4.078844
#> [11,] 4.297976 4.317174 3.996058
#> [12,] 4.123887 4.095410 4.118265
#> [13,] 4.283401 4.331614 4.340342
#> [14,] 4.829150 4.453842 4.327201
#> [15,] 3.730769 4.016503 4.353482
#> [16,] 4.164777 4.073234 4.240473
#> CCTACCAAGTGCGATG-b01 CCTACCATCCAAACTG-b01 CCTAGCTTCGGCATCG-b01
#> [1,] 4.430357 4.301754 4.805825
#> [2,] 4.010714 4.470175 4.260922
#> [3,] 4.245238 4.329825 4.367718
#> [4,] 4.126190 4.163743 4.549757
#> [5,] 4.695238 4.691228 4.444175
#> [6,] 4.062500 4.791813 4.060680
#> [7,] 4.430357 4.339181 4.195388
#> [8,] 4.743452 5.201170 5.048544
#> [9,] 4.318452 4.299415 4.690534
#> [10,] 4.206548 4.418713 4.458738
#> [11,] 4.209524 4.760234 4.638350
#> [12,] 4.257738 4.453801 4.572816
#> [13,] 4.522024 4.290058 4.316748
#> [14,] 4.069643 4.432749 4.632282
#> [15,] 4.307143 4.380117 4.507282
#> [16,] 4.320833 4.589474 4.212379
#> CCTATTAGTTGGTAAA-b01 CCTCTGAAGCGATATA-b01 CCTTCCCAGTGCGATG-b01
#> [1,] 4.281421 4.550586 4.902873
#> [2,] 4.379781 4.099042 3.998632
#> [3,] 4.562842 4.155485 3.811218
#> [4,] 4.560109 4.418530 3.901505
#> [5,] 4.508197 4.749734 4.990424
#> [6,] 4.214481 3.794462 3.978112
#> [7,] 4.845628 4.802982 3.443228
#> [8,] 4.758197 4.599574 5.233926
#> [9,] 4.635246 4.380192 4.403557
#> [10,] 4.289617 3.994675 3.589603
#> [11,] 4.250000 4.361022 4.201094
#> [12,] 4.568306 4.158679 3.961696
#> [13,] 3.954918 4.149095 5.030096
#> [14,] 4.565574 4.397231 4.563611
#> [15,] 4.530055 4.252396 3.521204
#> [16,] 4.159836 3.873269 4.083447
#> CCTTCCCTCATCGCTC-b01 CCTTCGAGTCGCGGTT-b01 CCTTTCTGTGACGGTA-b01
#> [1,] 4.176880 4.479416 4.302583
#> [2,] 3.835190 3.701195 4.162362
#> [3,] 4.086351 3.932271 4.369004
#> [4,] 4.302693 4.454183 4.327183
#> [5,] 5.304550 4.956175 4.659287
#> [6,] 4.259517 3.912351 4.607626
#> [7,] 5.258124 4.332005 4.382534
#> [8,] 4.258124 4.551129 4.617466
#> [9,] 4.121634 4.248340 4.500615
#> [10,] 4.131848 3.887118 4.366544
#> [11,] 4.275766 4.005312 4.180812
#> [12,] 4.147632 4.402390 4.665437
#> [13,] 4.317549 3.970784 3.977860
#> [14,] 4.459146 4.359894 4.225092
#> [15,] 3.907614 3.956175 4.066421
#> [16,] 4.300371 3.606906 4.279213
#> CGAACATCAGACAAAT-b01 CGAACATTCGCACTCT-b01 CGACCTTTCATGTCTT-b01
#> [1,] 4.190732 4.333782 4.205332
#> [2,] 4.038049 3.837147 3.753829
#> [3,] 3.704390 4.253028 3.724334
#> [4,] 4.103902 4.170929 4.098695
#> [5,] 5.325854 4.795424 5.626205
#> [6,] 4.042927 3.956931 3.871809
#> [7,] 5.030732 4.791386 5.321611
#> [8,] 4.500000 4.387618 4.115712
#> [9,] 4.080000 4.170929 3.717527
#> [10,] 3.980000 4.126514 3.977311
#> [11,] 4.270732 4.226110 4.154282
#> [12,] 3.836098 4.020188 3.748724
#> [13,] 4.250244 4.166891 4.161089
#> [14,] 4.581463 4.380888 4.273398
#> [15,] 3.747805 4.243607 3.781622
#> [16,] 3.992195 3.847914 3.790130
#> CGACTTCCAGCTCGAC-b01 CGACTTCCAGGACCCT-b01 CGAGAAGCAAATTGCC-b01
#> [1,] 4.371613 4.557808 4.099304
#> [2,] 4.593548 4.047023 4.115920
#> [3,] 4.615484 4.124245 4.118624
#> [4,] 4.326452 4.298102 4.105487
#> [5,] 4.343226 5.160052 5.216383
#> [6,] 4.250323 3.863676 4.153014
#> [7,] 4.252903 4.732959 4.953246
#> [8,] 5.000000 4.502157 4.500773
#> [9,] 4.589677 4.156169 4.216383
#> [10,] 4.205161 4.017256 4.086940
#> [11,] 4.491613 4.259707 4.121716
#> [12,] 4.534194 3.977998 4.107032
#> [13,] 4.721290 4.389560 4.293663
#> [14,] 4.278710 4.464625 4.492658
#> [15,] 4.363871 3.735116 4.035162
#> [16,] 4.225806 3.959016 4.114374
#> CGAGCACCATTAGCCA-b01 CGAGCACGTTCTGAAC-b01 CGATCGGGTCAGAAGC-b01
#> [1,] 4.288900 4.416899 4.286830
#> [2,] 3.675917 4.154132 3.993304
#> [3,] 3.759663 4.480037 4.483259
#> [4,] 4.199207 4.799443 4.310268
#> [5,] 5.689792 4.757660 4.526786
#> [6,] 4.043608 4.637883 4.561384
#> [7,] 5.393459 4.299907 4.318080
#> [8,] 4.352329 5.122563 4.835938
#> [9,] 3.928147 4.818942 4.345982
#> [10,] 3.469277 4.936862 4.366071
#> [11,] 3.946977 4.523677 4.450893
#> [12,] 3.884539 4.187558 4.436384
#> [13,] 4.316650 4.406685 4.361607
#> [14,] 4.362735 4.141133 4.065848
#> [15,] 3.937066 4.444754 4.406250
#> [16,] 3.580278 4.205200 4.246652
#> CGATGGCGTTCGCGAC-b01 CGATGTAGTATATCCG-b01 CGATGTATCCGTCATC-b01
#> [1,] 4.371447 4.372788 4.204126
#> [2,] 3.680233 4.057522 4.311075
#> [3,] 4.030362 4.227876 4.170467
#> [4,] 4.507752 4.358407 4.151466
#> [5,] 5.301680 4.405973 4.201954
#> [6,] 3.776486 3.872788 3.945168
#> [7,] 5.218992 4.359513 4.557546
#> [8,] 4.296512 5.319690 5.528773
#> [9,] 4.124677 4.713496 4.463084
#> [10,] 3.707364 4.191372 4.211183
#> [11,] 4.167313 4.370575 4.137351
#> [12,] 3.865633 4.671460 4.190011
#> [13,] 4.401809 4.506637 4.771987
#> [14,] 4.442506 4.481195 4.239957
#> [15,] 3.944444 4.753319 4.219870
#> [16,] 3.947674 4.167035 5.051574
#> CGATTGAGTGGAAAGA-b01 CGATTGATCCTGTACC-b01 CGCGGTACACCTATCC-b01
#> [1,] 4.250243 4.190476 4.212095
#> [2,] 4.499513 3.922932 4.462752
#> [3,] 4.211295 4.247494 3.969325
#> [4,] 4.241480 4.149749 4.375986
#> [5,] 4.587147 5.024436 4.763365
#> [6,] 3.985394 3.961153 4.093777
#> [7,] 4.658228 4.760652 4.106924
#> [8,] 4.486855 4.466792 4.962314
#> [9,] 4.156767 4.270677 4.431201
#> [10,] 4.008763 4.007519 4.376862
#> [11,] 4.466407 4.011278 4.503067
#> [12,] 4.094450 4.244987 4.313760
#> [13,] 4.277507 4.379073 4.206836
#> [14,] 4.668939 4.372807 4.539877
#> [15,] 4.103213 4.321429 4.020158
#> [16,] 3.847128 3.952381 4.635408
#> CGCGGTACAGGATTGG-b01 CGCGTTTAGGAACTGC-b01 CGCGTTTCATGGGACA-b01
#> [1,] 4.393812 4.595339 4.580437
#> [2,] 4.240506 4.229873 4.372393
#> [3,] 4.551805 4.420551 4.403674
#> [4,] 4.258322 4.381356 4.235353
#> [5,] 4.707923 4.429025 4.542701
#> [6,] 4.100328 4.293432 4.513903
#> [7,] 4.231130 4.046610 4.487090
#> [8,] 4.829348 4.715042 4.918073
#> [9,] 4.337084 4.351695 4.646475
#> [10,] 4.119550 4.230932 4.202582
#> [11,] 4.192686 4.238347 4.513406
#> [12,] 4.433662 4.636653 4.404667
#> [13,] 4.539147 4.459746 4.102284
#> [14,] 4.105954 4.316737 4.200099
#> [15,] 4.507736 4.032839 4.133069
#> [16,] 4.269573 4.288136 4.500000
#> CGCGTTTTCGTGGACC-b01 CGCTATCAGAGGTACC-b01 CGCTATCCAATTCCTT-b01
#> [1,] 4.359264 4.354197 4.017683
#> [2,] 4.495050 3.868025 3.970822
#> [3,] 4.490806 4.115963 4.153846
#> [4,] 4.263083 4.291121 4.238727
#> [5,] 4.783593 5.065502 5.094607
#> [6,] 3.861386 4.175158 3.930150
#> [7,] 4.325318 5.012130 4.880637
#> [8,] 5.260255 4.396895 4.493369
#> [9,] 4.198020 4.420670 3.921309
#> [10,] 4.304102 4.110626 4.061892
#> [11,] 4.417256 4.255216 4.734748
#> [12,] 4.103253 4.246967 3.838196
#> [13,] 4.199434 4.478894 4.080460
#> [14,] 4.311174 4.440563 4.448276
#> [15,] 4.268741 3.930616 3.996463
#> [16,] 4.336634 3.885492 4.003537
#> CGCTATCTCATGTAGC-b01 CGCTGGAAGTGTTTGC-b01 CGCTGGACAATGGAGC-b01
#> [1,] 4.507956 4.458559 4.395610
#> [2,] 4.476132 4.478699 4.132648
#> [3,] 4.370869 4.077459 4.090612
#> [4,] 4.015912 4.320682 4.265297
#> [5,] 4.605875 4.809450 5.181224
#> [6,] 4.093023 4.000000 3.783279
#> [7,] 4.281518 4.177382 4.770668
#> [8,] 4.780906 5.091402 4.695002
#> [9,] 4.222766 4.442293 4.384867
#> [10,] 4.137087 4.044926 3.927137
#> [11,] 3.996328 4.460883 4.197104
#> [12,] 4.330477 4.272657 3.997665
#> [13,] 4.318237 4.628195 4.237272
#> [14,] 3.888617 4.376452 4.667445
#> [15,] 4.576499 4.004648 3.827184
#> [16,] 4.279070 4.018590 3.927604
#> CGGACACAGTATCTCG-b01 CGGACACCACATTCGA-b01 CGGACTGGTGGTACAG-b01
#> [1,] 4.307789 4.121088 4.498255
#> [2,] 3.888191 4.688435 3.698953
#> [3,] 4.456030 4.012245 4.371728
#> [4,] 4.270101 4.370068 4.496510
#> [5,] 4.390704 4.220408 4.975567
#> [6,] 3.993719 4.291156 4.166667
#> [7,] 4.643216 4.142857 4.580279
#> [8,] 4.488693 4.903401 4.496510
#> [9,] 4.571608 5.100680 3.842932
#> [10,] 4.201005 4.580952 3.920593
#> [11,] 4.430905 4.295238 3.886562
#> [12,] 4.172111 4.565986 4.019197
#> [13,] 4.459799 4.670748 4.111693
#> [14,] 3.963568 4.474830 4.186736
#> [15,] 4.388191 4.677551 4.271379
#> [16,] 4.238693 4.155102 3.883944
#> CGGAGCTGTCCATGAT-b01 CGGAGTCCACGGATAG-b01 CGGAGTCCATGGTCAT-b01
#> [1,] 4.286307 4.459222 4.410676
#> [2,] 4.363071 4.045876 3.985053
#> [3,] 4.481328 4.207600 4.467616
#> [4,] 4.284232 4.246988 4.419217
#> [5,] 4.439834 5.003244 4.762278
#> [6,] 3.802905 4.034754 3.948043
#> [7,] 4.782849 4.873957 4.730249
#> [8,] 4.667358 4.479147 4.544484
#> [9,] 4.325726 4.170065 4.019929
#> [10,] 3.957123 4.141798 4.222776
#> [11,] 4.399723 4.277572 4.196441
#> [12,] 4.419087 3.993976 4.227758
#> [13,] 4.051867 3.960148 4.283274
#> [14,] 4.213693 4.514829 4.368683
#> [15,] 3.867220 3.843373 4.123132
#> [16,] 4.091286 4.041705 3.804270
#> CGGAGTCCATGGTCTA-b01 CGGAGTCGTTCCATGA-b01 CGGCTAGAGGGCTTGA-b01
#> [1,] 4.585005 4.290705 4.379569
#> [2,] 4.101373 3.729258 3.868791
#> [3,] 4.344245 4.054273 4.159325
#> [4,] 4.654699 4.236432 4.199625
#> [5,] 4.934530 5.268247 5.251172
#> [6,] 4.047518 3.833437 4.194939
#> [7,] 4.269271 4.937617 5.316776
#> [8,] 4.695882 4.346226 4.208997
#> [9,] 4.439282 4.056145 3.895970
#> [10,] 4.187962 4.051778 3.810684
#> [11,] 4.080253 4.040549 4.205248
#> [12,] 4.126716 4.121647 4.186504
#> [13,] 4.545935 4.119775 4.231490
#> [14,] 3.988384 4.369308 4.472352
#> [15,] 4.271383 4.104803 3.770384
#> [16,] 4.177402 3.752339 3.837863
#> CGGGTCACAAGCTGGA-b01 CGGGTCAGTTGGTGGA-b01 CGGTTAATCGCCGTGA-b01
#> [1,] 4.084371 4.246809 4.067402
#> [2,] 4.567082 4.479433 4.090686
#> [3,] 4.463347 4.041135 4.118873
#> [4,] 4.640387 4.276596 4.140931
#> [5,] 4.688797 4.499291 4.579657
#> [6,] 3.881051 4.204255 4.351716
#> [7,] 4.333333 4.319149 4.335784
#> [8,] 4.885201 4.692199 5.098039
#> [9,] 4.441217 4.665248 4.678922
#> [10,] 4.248963 4.307801 4.150735
#> [11,] 4.579530 4.201418 4.377451
#> [12,] 4.105118 4.479433 4.334559
#> [13,] 3.716459 4.591489 4.530637
#> [14,] 4.533887 4.266667 4.493873
#> [15,] 4.049793 3.900709 4.199755
#> [16,] 4.586445 4.469504 4.593137
#> CGTAGCGCACGGACAA-b01 CGTAGCGGTCGAACAG-b01 CGTCACTCAAACCCAT-b01
#> [1,] 4.647577 4.410569 4.205293
#> [2,] 4.286344 3.982385 4.215718
#> [3,] 4.054626 4.205962 4.160385
#> [4,] 4.140088 4.329268 4.319166
#> [5,] 4.695154 4.789973 4.694467
#> [6,] 3.851982 4.051491 3.935044
#> [7,] 4.214097 4.850949 4.616680
#> [8,] 4.913656 4.392954 4.676022
#> [9,] 4.040529 4.188347 4.372093
#> [10,] 3.733921 3.846883 3.922213
#> [11,] 4.273128 4.105691 4.612670
#> [12,] 4.239648 4.146341 4.338412
#> [13,] 4.022026 4.159892 4.158781
#> [14,] 4.372687 4.302168 4.635926
#> [15,] 3.755947 4.027100 3.846832
#> [16,] 4.136564 4.121951 3.960706
#> CGTCACTCAGGTCCAC-b01 CGTCACTTCTTACCGC-b01 CGTCAGGCACGGACAA-b01
#> [1,] 4.543385 4.381837 4.183086
#> [2,] 4.293030 4.131063 4.186574
#> [3,] 4.337127 4.422085 4.364429
#> [4,] 4.156472 4.174407 4.271142
#> [5,] 4.455192 4.754386 4.369660
#> [6,] 4.297297 4.231166 4.159547
#> [7,] 4.176387 4.529412 4.345248
#> [8,] 5.261735 4.639835 5.027899
#> [9,] 4.598862 4.500516 4.436792
#> [10,] 4.128023 4.205366 4.267655
#> [11,] 4.156472 4.184727 4.335658
#> [12,] 4.194879 4.697626 4.461203
#> [13,] 4.584637 4.433437 4.102877
#> [14,] 4.049787 4.033024 4.285963
#> [15,] 4.143670 4.261094 4.167393
#> [16,] 4.048364 4.575851 4.215344
#> CGTCAGGTCCCAACGG-b01 CGTCTACTCTAACCGA-b01 CGTGAGCCAAAGGCGT-b01
#> [1,] 4.612740 4.170464 4.648080
#> [2,] 3.778564 4.232913 4.231261
#> [3,] 3.840243 4.317128 4.380256
#> [4,] 4.479272 4.544142 4.556673
#> [5,] 5.195147 4.592555 4.818099
#> [6,] 3.900910 4.064280 3.873857
#> [7,] 4.657230 4.634052 4.597806
#> [8,] 4.706775 4.520952 4.429616
#> [9,] 4.350859 4.268104 4.257770
#> [10,] 3.889788 4.143613 3.969835
#> [11,] 4.024267 4.420057 4.111517
#> [12,] 4.072801 4.443450 4.005484
#> [13,] 4.504550 4.128560 4.104205
#> [14,] 4.347826 4.563263 4.253199
#> [15,] 3.659252 3.979251 4.085009
#> [16,] 4.045501 4.003662 3.895795
#> CGTGAGCCAATCACAC-b01 CGTGAGCTCGAGAACG-b01 CGTGAGCTCTTGTCAT-b01
#> [1,] 4.460754 4.636270 4.280950
#> [2,] 3.985729 4.174180 4.157150
#> [3,] 4.293578 4.514344 3.918140
#> [4,] 4.515800 4.831967 4.219808
#> [5,] 4.573904 4.596311 5.183426
#> [6,] 4.811417 3.993852 3.934310
#> [7,] 4.412844 4.432377 4.916625
#> [8,] 4.951070 4.930328 4.668519
#> [9,] 4.398573 4.596311 4.184437
#> [10,] 4.715596 4.409836 3.744315
#> [11,] 4.813456 4.228484 4.252653
#> [12,] 4.453619 4.446721 3.996463
#> [13,] 3.848114 4.286885 4.263264
#> [14,] 4.396534 4.434426 4.604346
#> [15,] 4.240571 4.510246 3.860030
#> [16,] 4.266055 4.450820 3.831228
#> CGTGTAATCAACGGGA-b01 CGTGTCTAGGTCGGAT-b01 CGTTAGAAGTACGATA-b01
#> [1,] 4.233907 4.616246 4.325354
#> [2,] 3.848311 4.075630 4.104461
#> [3,] 4.291906 4.630252 4.490751
#> [4,] 4.307839 4.273109 4.142546
#> [5,] 5.039516 4.429972 4.504897
#> [6,] 4.537285 3.774510 4.714908
#> [7,] 4.819630 4.345938 4.213275
#> [8,] 4.551944 4.658263 4.846572
#> [9,] 4.233270 4.110644 4.587595
#> [10,] 4.154238 4.147059 4.264418
#> [11,] 4.314850 4.071429 4.483134
#> [12,] 4.319312 4.361345 4.581066
#> [13,] 4.247929 3.984594 3.985854
#> [14,] 4.418738 3.952381 4.353645
#> [15,] 4.003187 4.414566 4.314472
#> [16,] 4.327597 4.067227 4.630033
#> CGTTAGACATCATCCC-b01 CGTTCTGCATAACCTG-b01 CGTTGGGGTCAATGTC-b01
#> [1,] 4.264957 4.258597 4.244521
#> [2,] 4.431624 4.026135 4.429066
#> [3,] 4.500000 4.718019 4.322953
#> [4,] 4.027350 4.698762 4.279123
#> [5,] 4.469231 4.602476 4.509804
#> [6,] 4.005983 4.348006 4.059977
#> [7,] 4.291453 4.547455 4.192618
#> [8,] 5.059829 4.855571 5.251442
#> [9,] 4.321368 4.511692 4.656286
#> [10,] 4.238462 4.392022 4.298731
#> [11,] 4.454701 4.317744 4.322953
#> [12,] 4.299145 4.585970 4.579008
#> [13,] 4.188889 4.132050 4.442907
#> [14,] 4.335043 4.231087 4.215686
#> [15,] 4.107692 4.213205 4.521338
#> [16,] 4.358974 4.035763 4.650519
#> CTAACTTAGTGAAGAG-b01 CTAAGACTCCGCGTTT-b01 CTAATGGCAGATCTGT-b01
#> [1,] 4.637832 4.257925 4.322399
#> [2,] 4.379364 3.969741 3.861097
#> [3,] 4.010943 4.370317 3.903639
#> [4,] 4.772277 4.004323 4.375705
#> [5,] 4.560188 4.354467 5.513070
#> [6,] 4.142783 3.827089 3.948744
#> [7,] 4.002084 4.521614 5.127114
#> [8,] 5.183429 5.023055 4.301384
#> [9,] 4.825951 3.880403 4.205023
#> [10,] 4.364252 4.286744 4.220912
#> [11,] 4.356957 4.273775 4.212199
#> [12,] 4.155810 4.445245 4.064070
#> [13,] 4.443460 4.595101 4.005638
#> [14,] 4.563314 3.985591 4.494618
#> [15,] 4.404377 4.128242 3.955407
#> [16,] 4.136008 4.298271 3.983086
#> CTACACCAGCGATATA-b01 CTACACCGTACATGTC-b01 CTACATTCAAGCTGTT-b01
#> [1,] 4.113579 4.644474 4.238717
#> [2,] 4.244069 3.644474 3.912114
#> [3,] 4.129732 3.739015 3.970309
#> [4,] 4.310197 4.185087 4.223278
#> [5,] 5.095911 4.904128 4.838480
#> [6,] 4.031045 3.845539 3.706651
#> [7,] 4.970469 4.725699 4.140143
#> [8,] 4.520697 4.252996 5.299287
#> [9,] 4.304139 4.426099 4.422803
#> [10,] 4.094649 3.814913 4.052257
#> [11,] 4.315497 3.990679 4.162708
#> [12,] 4.190308 3.889481 3.984561
#> [13,] 4.226906 4.198402 4.028504
#> [14,] 4.497981 4.450067 4.319477
#> [15,] 3.989652 3.840213 3.990499
#> [16,] 4.156739 3.780293 4.628266
#> CTACATTGTGTGCCTG-b01 CTACCCACATGTTGAC-b01 CTACCCATCTTATCTG-b01
#> [1,] 4.347797 4.822977 4.779796
#> [2,] 4.350508 3.988439 4.222474
#> [3,] 4.282712 3.937139 4.274688
#> [4,] 4.232542 4.237717 3.911464
#> [5,] 4.766780 4.823699 4.562997
#> [6,] 3.945085 4.010838 4.322361
#> [7,] 4.115932 4.476156 3.986379
#> [8,] 5.010169 4.765896 5.165721
#> [9,] 4.735593 4.513006 4.397276
#> [10,] 4.012881 3.938584 4.261067
#> [11,] 4.384407 4.268786 4.304200
#> [12,] 4.256271 4.192919 4.149830
#> [13,] 4.565424 4.419798 4.173666
#> [14,] 3.979661 4.197254 4.053348
#> [15,] 4.013559 4.022399 4.507378
#> [16,] 4.266441 4.039017 4.162316
#> CTACGTCTCAAGGTAA-b01 CTACGTCTCCCGGATG-b01 CTAGCCTAGGTCATCT-b01
#> [1,] 4.278169 4.647989 4.376357
#> [2,] 4.111502 3.941092 4.214717
#> [3,] 3.910798 4.456897 4.541616
#> [4,] 4.058685 4.472701 4.747889
#> [5,] 4.618545 4.387931 4.632087
#> [6,] 4.119718 4.567529 4.646562
#> [7,] 4.010563 4.613506 4.560917
#> [8,] 4.812207 4.827586 4.975875
#> [9,] 4.237089 4.497126 4.775633
#> [10,] 4.214789 4.268678 4.428227
#> [11,] 4.365023 4.428161 4.447527
#> [12,] 4.171362 4.386494 4.369119
#> [13,] 4.288732 4.160920 4.494572
#> [14,] 4.438967 4.265805 4.683957
#> [15,] 4.078638 4.175287 4.188179
#> [16,] 4.158451 4.165230 4.372738
#> CTAGCCTCATAACCTG-b01 CTAGCCTGTAGGGACT-b01 CTAGTGAGTCCGCTGA-b01
#> [1,] 4.338475 4.215831 4.200553
#> [2,] 3.992067 3.920273 4.302905
#> [3,] 4.164390 4.174829 4.414938
#> [4,] 4.450859 4.289294 4.493776
#> [5,] 5.384310 5.191913 4.986169
#> [6,] 4.068312 3.968109 3.821577
#> [7,] 5.074482 4.778474 4.627939
#> [8,] 4.239312 4.547267 4.583679
#> [9,] 4.274130 3.963554 3.975104
#> [10,] 3.980167 4.029043 4.128631
#> [11,] 4.134861 4.104214 4.282158
#> [12,] 4.027766 4.117882 4.109267
#> [13,] 4.198325 3.968679 4.168741
#> [14,] 4.554429 4.411731 4.477178
#> [15,] 3.955928 3.772210 3.940526
#> [16,] 3.962098 3.846811 4.186722
#> CTCAGAACATTCACTT-b01 CTCAGAAGTGAACCTT-b01 CTCATTAAGGTGTGGT-b01
#> [1,] 4.107237 4.400000 4.261509
#> [2,] 3.995246 4.356021 4.234868
#> [3,] 4.117802 4.531937 4.164962
#> [4,] 4.211305 4.370681 4.249574
#> [5,] 4.920232 4.642932 5.161125
#> [6,] 3.761226 4.146597 4.028772
#> [7,] 4.867406 4.352880 4.574595
#> [8,] 4.567353 4.969634 4.392583
#> [9,] 4.511358 4.371728 4.188619
#> [10,] 3.871632 4.125654 4.105499
#> [11,] 4.120444 4.213613 4.391944
#> [12,] 4.204437 4.520419 4.823529
#> [13,] 4.234548 4.607330 4.431373
#> [14,] 4.424194 4.163351 4.176044
#> [15,] 3.952985 4.064921 3.679241
#> [16,] 4.025357 4.318325 4.790494
#> CTCATTACAAGCGTAG-b01 CTCATTAGTGAGCGAT-b01 CTCGAGGCAAGCGTAG-b01
#> [1,] 4.444636 4.211937 4.120773
#> [2,] 3.811719 4.702801 4.339372
#> [3,] 3.938389 4.375152 4.298309
#> [4,] 4.403705 4.181486 4.350242
#> [5,] 5.293839 4.370280 4.399758
#> [6,] 3.954761 4.103532 4.276570
#> [7,] 5.013356 4.126675 4.554348
#> [8,] 4.339078 5.506699 5.150966
#> [9,] 4.096941 4.330085 4.169082
#> [10,] 3.944421 4.074300 4.268116
#> [11,] 4.053425 4.514007 4.384058
#> [12,] 3.902628 4.472594 4.586957
#> [13,] 4.178371 3.767357 4.362319
#> [14,] 4.432572 4.950061 4.007246
#> [15,] 4.028005 4.152253 4.228261
#> [16,] 3.918570 4.235079 4.393720
#> CTCGAGGTCACCTCGT-b01 CTCGGAGAGCTCAACT-b01 CTCGGAGTCACTCCTG-b01
#> [1,] 4.282517 4.367978 4.505737
#> [2,] 4.142657 4.106742 3.947043
#> [3,] 4.334266 4.133427 4.360106
#> [4,] 4.812587 4.200843 4.517211
#> [5,] 4.718881 4.367978 4.722860
#> [6,] 4.163636 4.483146 4.148279
#> [7,] 3.969231 4.369382 4.350397
#> [8,] 5.195804 5.095506 4.942630
#> [9,] 4.801399 4.522472 4.567520
#> [10,] 4.055944 4.212079 4.072374
#> [11,] 4.402797 4.543539 4.021183
#> [12,] 4.418182 3.983146 4.465137
#> [13,] 4.200000 4.412921 4.458959
#> [14,] 4.818182 4.251404 4.281553
#> [15,] 4.279720 4.157303 4.037070
#> [16,] 3.928671 4.448034 4.207414
#> CTCGGGACACGTCAGC-b01 CTCGGGATCCCAAGTA-b01 CTCGTACCATGCCACG-b01
#> [1,] 4.675963 4.229229 4.516999
#> [2,] 4.796813 4.003504 3.830012
#> [3,] 4.077025 4.064565 4.334115
#> [4,] 4.123506 4.305806 4.369285
#> [5,] 4.120850 5.157157 4.677608
#> [6,] 4.645418 4.052553 3.821805
#> [7,] 4.183267 4.869870 4.801876
#> [8,] 5.067729 4.408909 4.349355
#> [9,] 4.233732 4.026527 4.161782
#> [10,] 4.752988 3.913413 3.783118
#> [11,] 4.265604 4.147147 4.055100
#> [12,] 4.685259 3.882382 4.093787
#> [13,] 4.390438 4.088088 4.309496
#> [14,] 4.572377 4.390891 4.274326
#> [15,] 4.173971 3.869870 4.037515
#> [16,] 4.662683 3.852352 4.036342
#> CTCGTCACAGCGATCC-b01 CTCGTCACAGCTTCGG-b01 CTCTACGCAAGAAAGG-b01
#> [1,] 4.427556 4.632275 4.725153
#> [2,] 4.059111 4.138889 3.750920
#> [3,] 4.208444 4.756614 4.333742
#> [4,] 4.325333 4.382275 4.323926
#> [5,] 4.788000 4.562169 4.969325
#> [6,] 3.960444 4.718254 3.776687
#> [7,] 4.549778 4.410053 4.860123
#> [8,] 4.623556 4.919312 4.358282
#> [9,] 4.343111 4.441799 4.246626
#> [10,] 4.027556 4.644180 4.020859
#> [11,] 4.299556 4.457672 3.948466
#> [12,] 4.233333 4.871693 4.103067
#> [13,] 4.288444 3.719577 4.376687
#> [14,] 4.444000 4.100529 4.462577
#> [15,] 4.031556 4.145503 3.985276
#> [16,] 4.152889 4.214286 3.823313
#> CTCTGGTAGTTCGCAT-b01 CTCTGGTTCTCAACTT-b01 CTGAAGTTCGGTTAAC-b01
#> [1,] 4.320148 4.163486 4.491839
#> [2,] 4.014750 4.106234 3.933624
#> [3,] 4.056990 4.527354 4.156692
#> [4,] 4.389876 4.260814 4.268770
#> [5,] 5.008046 5.098601 4.656148
#> [6,] 4.157895 4.096692 3.776931
#> [7,] 4.835065 4.803435 4.609358
#> [8,] 4.603419 4.379135 4.494015
#> [9,] 4.178009 4.144402 4.399347
#> [10,] 4.174321 4.094148 3.887922
#> [11,] 4.260476 4.328244 4.182807
#> [12,] 4.120684 4.164122 4.092492
#> [13,] 4.123031 4.208651 4.249184
#> [14,] 4.443513 4.465649 4.299238
#> [15,] 4.119008 4.118957 4.153428
#> [16,] 4.116326 4.286896 3.780196
#> CTGATAGCAAAGGCGT-b01 CTGCCTACACTGTTAG-b01 CTGCCTAGTCCGCTGA-b01
#> [1,] 4.158361 4.253501 4.332008
#> [2,] 4.071982 4.226891 3.659046
#> [3,] 4.610188 4.223389 3.978131
#> [4,] 4.401993 4.236695 4.363817
#> [5,] 4.582503 4.566527 4.867793
#> [6,] 4.171650 4.315826 3.626243
#> [7,] 4.323367 4.744398 4.759443
#> [8,] 4.834994 4.692577 4.666004
#> [9,] 4.616833 4.619748 4.141153
#> [10,] 4.335548 4.217087 4.150099
#> [11,] 4.643411 3.957983 4.204771
#> [12,] 4.738649 4.561625 4.179920
#> [13,] 4.078627 4.563725 3.979125
#> [14,] 4.400886 4.210784 4.419483
#> [15,] 4.165006 4.065826 4.199801
#> [16,] 4.327796 4.350140 4.163022
#> CTGCTGTCAGGCTCAC-b01 CTGCTGTGTAAACGCG-b01 CTGCTGTTCTGATTCT-b01
#> [1,] 4.636159 4.514532 4.559129
#> [2,] 4.551388 3.905274 4.077801
#> [3,] 4.220555 3.916039 4.502075
#> [4,] 4.280570 4.837460 4.429461
#> [5,] 4.458365 4.797632 4.332988
#> [6,] 4.498125 3.758881 4.246888
#> [7,] 4.210803 4.620022 4.251037
#> [8,] 4.833458 4.412271 4.909751
#> [9,] 4.625656 4.156082 4.307054
#> [10,] 4.568642 3.893434 4.167012
#> [11,] 4.330833 3.981701 4.501037
#> [12,] 4.502626 4.018299 4.557054
#> [13,] 4.450863 4.316469 4.237552
#> [14,] 4.210803 4.192680 4.190871
#> [15,] 4.433608 3.940797 4.208506
#> [16,] 4.459865 4.066738 4.389004
#> CTGTGCTAGACTTTCG-b01 CTGTGCTAGCGGCTTC-b01 CTGTGCTCACGAAATA-b01
#> [1,] 4.335535 4.691678 4.474265
#> [2,] 3.793263 4.499318 3.909467
#> [3,] 4.135403 4.383356 4.379596
#> [4,] 4.354029 4.253752 4.485754
#> [5,] 5.169749 4.324693 5.159926
#> [6,] 4.060106 3.956344 3.979779
#> [7,] 5.264861 3.929059 4.633272
#> [8,] 4.710700 4.930423 4.546875
#> [9,] 4.155218 4.450205 4.138787
#> [10,] 3.887054 4.699864 4.000460
#> [11,] 4.157199 4.293315 4.377757
#> [12,] 3.930647 4.469304 4.134651
#> [13,] 4.095112 4.095498 4.301471
#> [14,] 4.388375 4.090041 4.557904
#> [15,] 3.843461 4.060027 3.961857
#> [16,] 4.071334 4.188267 4.107537
#> CTGTTTAGTAATAGCA-b01 CTTAACTAGTACACCT-b01 CTTAACTAGTGCGATG-b01
#> [1,] 4.495349 4.411511 4.183221
#> [2,] 4.115116 3.962590 4.199614
#> [3,] 4.233721 3.962590 4.019769
#> [4,] 4.377907 4.353237 4.255545
#> [5,] 4.647674 5.359712 5.169238
#> [6,] 3.781395 4.005755 3.988428
#> [7,] 4.556977 5.203597 4.973481
#> [8,] 4.425581 4.374820 4.537608
#> [9,] 4.053488 4.258273 4.088717
#> [10,] 4.173256 3.966906 4.079556
#> [11,] 4.106977 4.292086 4.372228
#> [12,] 4.425581 3.948921 4.018804
#> [13,] 4.254651 4.367626 4.301832
#> [14,] 4.490698 4.428777 4.538091
#> [15,] 4.187209 3.876978 3.884764
#> [16,] 3.934884 4.160432 4.100771
#> CTTACCGCAGATGGGT-b01 CTTACCGGTTCGAATC-b01 CTTAGGACACGCCAGT-b01
#> [1,] 4.311489 4.359829 4.113997
#> [2,] 4.042128 4.445299 4.463203
#> [3,] 4.077872 4.481197 4.189033
#> [4,] 4.482979 4.331624 4.362193
#> [5,] 5.061277 4.804274 4.399711
#> [6,] 3.840851 4.432479 4.164502
#> [7,] 4.774043 4.647863 4.330447
#> [8,] 4.593617 4.706838 5.064935
#> [9,] 4.175319 4.472650 4.454545
#> [10,] 3.895745 4.379487 4.333333
#> [11,] 4.182128 4.388034 4.271284
#> [12,] 3.965957 4.958120 4.271284
#> [13,] 4.257872 4.359829 4.256854
#> [14,] 4.494043 4.152991 4.036075
#> [15,] 3.791064 4.353846 4.307359
#> [16,] 4.175319 4.504274 4.066378
#> CTTAGGACATGTAGTC-b01 CTTAGGATCTGGCGAC-b01 CTTCTCTCATCCGCGA-b01
#> [1,] 4.041766 4.040075 4.425551
#> [2,] 4.460621 4.041327 3.703125
#> [3,] 4.108592 3.882279 4.210478
#> [4,] 4.513126 4.186600 4.139706
#> [5,] 4.398568 5.259236 4.731618
#> [6,] 4.643198 4.087038 3.842831
#> [7,] 4.170644 5.005009 4.840993
#> [8,] 5.063246 4.457733 4.735294
#> [9,] 4.710024 4.073889 4.312500
#> [10,] 4.466587 3.859737 4.051471
#> [11,] 4.916468 3.983719 4.153493
#> [12,] 4.404535 3.921728 4.164522
#> [13,] 4.379475 4.130244 4.670956
#> [14,] 4.326969 4.360050 4.163603
#> [15,] 4.556086 3.828428 4.088235
#> [16,] 4.359189 4.098936 4.164522
#> CTTCTCTGTAGAGCTG-b01 CTTCTCTTCCGTCAAA-b01 CTTGGCTTCATTCACT-b01
#> [1,] 4.076537 4.708298 4.375591
#> [2,] 4.131744 4.166806 4.310236
#> [3,] 4.028858 4.017603 4.427559
#> [4,] 4.058971 4.054484 4.262992
#> [5,] 4.199498 4.773680 4.590551
#> [6,] 4.910916 4.113160 4.193701
#> [7,] 4.215809 4.161777 4.356693
#> [8,] 4.976161 4.912825 5.021260
#> [9,] 4.653701 4.429170 4.703937
#> [10,] 3.986198 4.538139 4.411024
#> [11,] 4.143036 4.103101 4.322047
#> [12,] 4.321205 4.236379 4.386614
#> [13,] 4.053952 4.734283 4.435433
#> [14,] 4.792974 4.179380 4.278740
#> [15,] 4.062735 4.174350 4.018898
#> [16,] 4.730238 4.219614 4.403150
#> CTTTGCGAGAAGGGTA-b01 CTTTGCGTCACGACTA-b01 CTTTGCGTCATAACCG-b01
#> [1,] 4.136256 4.647314 4.622391
#> [2,] 4.269453 4.166034 3.987192
#> [3,] 4.156303 4.485621 4.138994
#> [4,] 4.366633 4.181226 4.493833
#> [5,] 5.148148 4.891481 5.036528
#> [6,] 4.159701 4.323386 3.928368
#> [7,] 4.901461 4.708627 4.794592
#> [8,] 4.374448 4.764514 4.407021
#> [9,] 4.301393 4.348888 4.244782
#> [10,] 4.148148 4.248508 3.899905
#> [11,] 4.128440 4.635377 4.256641
#> [12,] 4.057085 4.442214 4.419355
#> [13,] 4.302073 4.190993 4.482448
#> [14,] 4.492015 4.513294 4.505218
#> [15,] 3.900102 3.988606 3.785579
#> [16,] 4.162419 4.301682 4.322581
#> GAAACTCAGACCTAGG-b01 GAAATGAAGGCCCTCA-b01 GAACATCAGAGCTTCT-b01
#> [1,] 4.411765 4.344760 4.230665
#> [2,] 4.383809 3.942214 4.434193
#> [3,] 4.496214 4.118022 4.328358
#> [4,] 4.428072 4.293830 4.484396
#> [5,] 4.659872 5.092067 4.739484
#> [6,] 4.739080 3.839373 4.225237
#> [7,] 4.411182 4.611166 4.830393
#> [8,] 4.951660 4.547013 4.697422
#> [9,] 4.701223 4.272282 4.439620
#> [10,] 4.295865 3.980411 4.286296
#> [11,] 4.581829 4.133692 4.449118
#> [12,] 4.609202 4.085211 4.824966
#> [13,] 4.230052 4.439275 4.705563
#> [14,] 4.363425 4.453477 4.099050
#> [15,] 4.285964 4.088639 4.405699
#> [16,] 4.298195 4.060235 4.485753
#> GAACATCGTCTAACGT-b01 GAACCTATCCCTGACT-b01 GAACCTATCGCATGAT-b01
#> [1,] 4.390960 4.716334 4.363336
#> [2,] 4.141243 4.079201 3.660611
#> [3,] 4.432768 4.233843 4.232040
#> [4,] 4.362712 4.380494 4.101569
#> [5,] 4.453107 4.795535 4.980182
#> [6,] 4.610169 3.840893 3.849711
#> [7,] 4.103955 4.707873 4.714286
#> [8,] 4.742373 4.509753 4.446738
#> [9,] 4.400000 4.232902 4.215524
#> [10,] 4.405650 4.070270 3.712634
#> [11,] 4.651977 4.334900 4.274154
#> [12,] 4.587571 4.419271 4.220479
#> [13,] 4.239548 4.356052 4.393064
#> [14,] 4.514124 4.386839 4.303055
#> [15,] 4.218079 3.725264 4.063584
#> [16,] 4.228249 4.352996 4.040462
#> GAACCTATCGGATGGA-b01 GAAGCAGCAGATTGCT-b01 GAAGCAGGTTTGGGCC-b01
#> [1,] 4.313089 4.364763 4.330460
#> [2,] 4.528796 4.319339 4.665230
#> [3,] 4.332984 4.202340 4.573276
#> [4,] 4.477487 4.536476 4.260057
#> [5,] 4.400000 4.598073 4.313218
#> [6,] 4.515183 3.771851 4.067529
#> [7,] 4.352880 4.543703 4.295977
#> [8,] 4.913089 4.680317 4.755747
#> [9,] 4.334031 4.409498 4.254310
#> [10,] 4.436649 3.930833 4.389368
#> [11,] 4.652356 4.438059 4.281609
#> [12,] 4.383246 4.094288 4.438218
#> [13,] 3.833508 4.216105 4.395115
#> [14,] 4.319372 4.741913 4.235632
#> [15,] 4.338220 3.857192 4.181034
#> [16,] 4.406283 3.853063 4.405172
#> GAATAAGAGAGGTAGA-b01 GAATGAACAAATTGCC-b01 GACACGCTCATACGGT-b01
#> [1,] 4.574449 4.562919 4.185145
#> [2,] 3.612132 4.942666 4.305705
#> [3,] 4.374081 4.387937 4.449946
#> [4,] 4.651654 4.172003 4.588805
#> [5,] 5.150735 4.369322 4.588805
#> [6,] 3.620404 4.267312 4.263724
#> [7,] 4.977941 4.349963 4.190527
#> [8,] 4.422794 4.995532 4.854682
#> [9,] 4.193015 4.121370 4.792250
#> [10,] 4.144301 4.218168 4.515608
#> [11,] 4.325368 4.535369 3.982777
#> [12,] 3.980699 4.774386 4.503767
#> [13,] 4.095588 4.344751 4.212056
#> [14,] 4.315257 4.411020 4.369214
#> [15,] 3.920956 3.986597 4.172228
#> [16,] 4.154412 4.419955 4.208827
#> GACAGAGCAAGCGTAG-b01 GACAGAGCACGAAACG-b01 GACAGAGGTTCGAATC-b01
#> [1,] 4.231201 4.561884 4.319161
#> [2,] 4.246914 4.131435 4.421866
#> [3,] 4.489338 4.232202 4.281612
#> [4,] 4.593715 4.412924 4.201546
#> [5,] 4.794613 4.969332 4.436223
#> [6,] 4.582492 4.164294 4.234677
#> [7,] 4.529742 4.728368 4.368305
#> [8,] 4.726150 4.548740 4.979017
#> [9,] 4.762065 4.214677 4.599117
#> [10,] 4.419753 4.025192 4.202098
#> [11,] 4.540965 4.074480 4.278851
#> [12,] 4.261504 4.140197 4.272225
#> [13,] 4.264871 4.153341 4.590834
#> [14,] 4.438833 4.122673 4.300387
#> [15,] 4.392817 4.145674 3.954169
#> [16,] 4.131313 4.044907 4.558807
#> GACAGAGTCGTCTGCT-b01 GACCAATAGAGTACCG-b01 GACCAATTCACTGGGC-b01
#> [1,] 4.273373 4.391261 4.595376
#> [2,] 3.922362 4.359484 4.121387
#> [3,] 4.171132 4.571003 4.351445
#> [4,] 4.277747 4.272095 4.171098
#> [5,] 5.457627 4.630586 4.833526
#> [6,] 4.026244 4.901688 4.181503
#> [7,] 5.247130 4.216485 4.671676
#> [8,] 4.258065 5.083416 4.692486
#> [9,] 4.088026 4.316783 4.571098
#> [10,] 4.125752 4.544191 4.329480
#> [11,] 4.093494 4.553128 4.198844
#> [12,] 4.089666 4.584906 4.210405
#> [13,] 4.190815 4.108242 4.159538
#> [14,] 4.421542 4.454816 4.335260
#> [15,] 3.820120 4.590864 4.290173
#> [16,] 4.149809 4.353525 4.276301
#> GACGTGCGTCCAGTTA-b01 GACGTTACAAATCCGT-b01 GACGTTACAGACAAGC-b01
#> [1,] 4.468788 4.650161 4.101680
#> [2,] 4.241126 3.879440 4.261715
#> [3,] 4.456548 3.794403 4.223696
#> [4,] 4.386781 4.364909 4.133510
#> [5,] 4.632803 5.062433 4.526083
#> [6,] 4.823745 3.516685 4.069850
#> [7,] 4.292534 4.903122 4.241379
#> [8,] 5.132191 4.883746 4.574713
#> [9,] 4.771114 4.085038 4.530504
#> [10,] 4.538556 3.682454 4.335986
#> [11,] 4.516524 4.145318 4.208665
#> [12,] 4.447980 3.712594 4.388152
#> [13,] 4.329253 3.868676 4.511052
#> [14,] 4.352509 4.592034 4.451813
#> [15,] 4.074663 3.849300 4.190981
#> [16,] 4.271726 3.836383 4.539346
#> GACTACAGTGGTCTCG-b01 GACTACATCACGCGGT-b01 GACTACATCAGCGATT-b01
#> [1,] 4.151737 4.383142 4.286967
#> [2,] 4.292048 3.683269 4.179198
#> [3,] 4.159506 4.065134 4.476190
#> [4,] 4.228519 4.288633 4.481203
#> [5,] 5.027879 4.628352 4.736842
#> [6,] 3.774680 4.372925 4.048872
#> [7,] 5.096435 4.840358 4.497494
#> [8,] 4.646709 4.584930 4.974937
#> [9,] 4.030622 4.464879 4.199248
#> [10,] 3.920018 3.874840 4.223058
#> [11,] 4.358318 4.088123 4.201754
#> [12,] 3.851005 4.210728 4.325815
#> [13,] 3.946069 4.567050 4.604010
#> [14,] 4.727605 4.754789 4.347118
#> [15,] 3.753199 3.743295 4.352130
#> [16,] 4.070384 3.844189 4.010025
#> GACTACATCTCCTATA-b01 GACTGCGAGATCCCAT-b01 GACTGCGAGGGCTTCC-b01
#> [1,] 4.132426 4.829980 4.252941
#> [2,] 4.251238 3.323944 4.376471
#> [3,] 4.522277 3.724346 4.654412
#> [4,] 4.334158 4.308853 4.586765
#> [5,] 4.275990 5.235412 4.379412
#> [6,] 4.414604 3.753521 3.830882
#> [7,] 4.488861 4.943662 4.471324
#> [8,] 4.960396 4.156942 4.737500
#> [9,] 4.831683 4.215292 4.311765
#> [10,] 4.195545 3.682093 4.296324
#> [11,] 4.379950 4.232394 4.259559
#> [12,] 4.430693 4.086519 4.183824
#> [13,] 3.987624 4.381288 4.252206
#> [14,] 4.622525 4.283702 4.406618
#> [15,] 4.194307 3.787726 4.127206
#> [16,] 4.424505 3.765594 4.322794
#> GACTGCGAGTTAGGTA-b01 GACTGCGGTCGCTTCT-b01 GAGCAGAAGCTACCTA-b01
#> [1,] 4.334795 4.163085 4.380772
#> [2,] 4.421053 4.217446 4.177103
#> [3,] 4.314327 4.204804 4.193548
#> [4,] 4.188596 4.606827 4.197976
#> [5,] 4.423977 4.719343 5.056293
#> [6,] 4.118421 3.998736 3.945604
#> [7,] 4.288012 4.103666 5.003163
#> [8,] 4.754386 5.169406 4.272612
#> [9,] 4.388889 4.515803 4.273877
#> [10,] 3.969298 4.457649 4.135990
#> [11,] 4.668129 4.649810 4.351676
#> [12,] 4.299708 4.466498 4.247944
#> [13,] 4.369883 4.752212 4.135990
#> [14,] 3.941520 4.251580 4.125237
#> [15,] 4.102339 4.450063 4.449083
#> [16,] 4.181287 4.232617 4.029096
#> GAGCAGAAGGAGCGTT-b01 GAGGTGAAGATGTTAG-b01 GAGGTGATCGTAGGTT-b01
#> [1,] 4.280098 4.498008 4.101108
#> [2,] 4.140049 4.334661 4.162050
#> [3,] 4.386978 4.423639 4.265928
#> [4,] 4.414005 4.171315 4.829640
#> [5,] 4.501229 4.735724 4.649584
#> [6,] 3.987715 4.463479 4.387812
#> [7,] 4.340295 4.450199 4.307479
#> [8,] 5.012285 5.006640 4.923823
#> [9,] 4.538084 4.187251 4.429363
#> [10,] 4.171990 4.334661 4.095568
#> [11,] 4.292383 4.249668 4.228532
#> [12,] 4.511057 4.132802 4.281163
#> [13,] 4.276413 4.602922 4.342105
#> [14,] 4.090909 4.228420 4.443213
#> [15,] 4.292383 3.956175 4.174515
#> [16,] 4.468059 4.512616 4.196676
#> GATCAGTAGATCCCGC-b01 GATCAGTGTGACTCAT-b01 GATCGATCAATCAGAA-b01
#> [1,] 4.467098 4.478621 4.618312
#> [2,] 4.389428 4.068966 3.993460
#> [3,] 4.252427 4.575172 4.129608
#> [4,] 4.168285 4.325517 4.514863
#> [5,] 4.565264 4.284138 4.668252
#> [6,] 4.313916 4.416552 4.224138
#> [7,] 4.278317 4.379310 4.398335
#> [8,] 5.056095 5.380690 4.806183
#> [9,] 4.426106 4.868966 4.397741
#> [10,] 4.432578 4.147586 4.095719
#> [11,] 3.978425 4.211034 4.155172
#> [12,] 4.501618 4.557241 4.379905
#> [13,] 4.574973 4.228966 4.266350
#> [14,] 4.240561 4.528276 4.548751
#> [15,] 4.060410 4.100690 4.166468
#> [16,] 4.478964 4.188966 4.183115
#> GATCGTACAACTTGAC-b01 GATCTAGCACCGAATT-b01 GATGAGGAGACAGACC-b01
#> [1,] 4.581867 4.348561 4.204148
#> [2,] 3.825440 3.801627 4.144105
#> [3,] 4.198917 4.267209 4.245633
#> [4,] 4.273342 4.183354 4.262009
#> [5,] 4.870095 4.983730 4.775109
#> [6,] 3.926928 4.100125 4.021834
#> [7,] 4.634641 4.680225 4.367904
#> [8,] 4.813261 4.333542 4.919214
#> [9,] 4.151556 4.165207 4.521834
#> [10,] 3.944520 3.977472 3.982533
#> [11,] 4.208390 4.217146 4.423581
#> [12,] 4.081191 4.059449 4.106987
#> [13,] 4.230041 4.311014 4.731441
#> [14,] 4.289581 4.483730 4.063319
#> [15,] 4.411367 3.882979 4.091703
#> [16,] 4.400541 4.015019 4.125546
#> GATGAGGTCTACCAGA-b01 GATGCTAGTCGGCATC-b01 GATTCAGCACGAGGTA-b01
#> [1,] 4.423645 4.166260 4.419540
#> [2,] 4.068966 4.052033 3.873563
#> [3,] 4.236453 4.184959 4.022270
#> [4,] 4.119458 4.170325 4.346264
#> [5,] 4.688424 4.990650 5.248563
#> [6,] 3.757389 4.153252 3.897270
#> [7,] 4.860837 5.071951 5.086207
#> [8,] 4.363300 4.512602 4.660920
#> [9,] 4.528325 4.245935 4.160201
#> [10,] 3.837438 4.165041 3.806753
#> [11,] 4.160099 4.176829 4.198994
#> [12,] 4.198276 4.280894 4.094109
#> [13,] 4.338670 4.389837 4.201868
#> [14,] 4.538177 4.423171 4.506466
#> [15,] 3.911330 4.110569 3.847701
#> [16,] 4.045567 4.275610 4.044540
#> GCAAACTAGTAGCCGA-b01 GCAAACTGTGGAAAGA-b01 GCAAACTGTTGTACAC-b01
#> [1,] 4.391437 4.174385 4.426573
#> [2,] 4.189602 4.371201 4.340326
#> [3,] 4.219164 4.479740 4.360140
#> [4,] 4.256881 4.272793 4.632867
#> [5,] 4.364934 4.460203 4.562937
#> [6,] 4.356779 4.092619 3.842657
#> [7,] 4.286442 4.465268 4.303030
#> [8,] 5.074414 4.523155 5.128205
#> [9,] 4.632008 4.325615 4.800699
#> [10,] 4.323140 4.140376 4.111888
#> [11,] 3.951070 4.472504 4.662005
#> [12,] 4.239551 4.303184 4.748252
#> [13,] 4.591233 4.030391 3.935897
#> [14,] 4.568807 4.469609 4.266900
#> [15,] 4.097859 4.042692 4.539627
#> [16,] 4.292559 4.049204 4.244755
#> GCAATCATCCCTCAGT-b01 GCACATAAGCCCAATT-b01 GCACATACACCAGTTA-b01
#> [1,] 4.603120 4.516824 4.516862
#> [2,] 3.919411 4.777927 4.434274
#> [3,] 3.954073 4.390310 4.121817
#> [4,] 4.399480 4.349933 4.361321
#> [5,] 5.091854 4.843876 4.924295
#> [6,] 3.958406 4.242261 4.146593
#> [7,] 4.410745 4.484522 4.889195
#> [8,] 4.587522 5.271871 4.602202
#> [9,] 4.168977 4.462988 4.233999
#> [10,] 3.943674 4.425303 4.238128
#> [11,] 4.331023 4.131898 4.139711
#> [12,] 4.056326 4.691790 4.396421
#> [13,] 4.084922 4.398385 4.263593
#> [14,] 4.295494 4.220727 4.256022
#> [15,] 4.084922 4.792732 3.940812
#> [16,] 4.104853 4.323015 4.055747
#> GCACTCTTCCCGGATG-b01 GCAGCCAAGAAGGACA-b01 GCAGCCAGTTCCGTCT-b01
#> [1,] 4.499067 4.537662 4.052820
#> [2,] 3.847015 4.403896 4.373321
#> [3,] 4.069963 4.016883 4.529991
#> [4,] 4.333955 4.431169 4.444942
#> [5,] 4.803172 4.262338 4.310654
#> [6,] 4.209888 4.162338 3.916741
#> [7,] 4.936567 4.129870 4.123545
#> [8,] 4.714552 4.989610 4.817368
#> [9,] 4.335821 4.692208 4.297225
#> [10,] 4.143657 4.487013 4.445837
#> [11,] 4.111007 4.363636 4.253357
#> [12,] 4.318097 4.323377 4.508505
#> [13,] 4.277985 4.353247 4.196956
#> [14,] 4.264925 4.841558 4.428827
#> [15,] 3.981343 4.253247 3.988362
#> [16,] 4.041045 4.274026 4.412713
#> GCAGCCATCAGCGATT-b01 GCAGTTACAAGAGGCT-b01 GCAGTTACATGAGCGA-b01
#> [1,] 4.315236 4.122197 4.165038
#> [2,] 3.804729 4.323991 4.192182
#> [3,] 4.070928 4.713004 4.380022
#> [4,] 4.751313 4.276906 4.374593
#> [5,] 4.435201 4.318386 4.538545
#> [6,] 4.253065 4.232063 4.246471
#> [7,] 4.467601 4.480942 4.149837
#> [8,] 4.784588 4.994395 4.880565
#> [9,] 4.269702 4.448430 4.219327
#> [10,] 3.882662 4.597534 3.973941
#> [11,] 4.360771 4.144619 4.175896
#> [12,] 4.061296 4.276906 4.079262
#> [13,] 4.270578 4.496637 4.453855
#> [14,] 4.272329 4.260090 4.066232
#> [15,] 3.952715 4.250000 4.036916
#> [16,] 4.054291 4.550448 4.091205
#> GCATACAAGGTAAACT-b01 GCATGATAGTTGTAGA-b01 GCATGATGTTTGACTG-b01
#> [1,] 4.130252 4.519359 4.329545
#> [2,] 4.027731 4.161549 4.025253
#> [3,] 4.570588 4.162884 4.118687
#> [4,] 4.281513 4.193591 4.171717
#> [5,] 4.536134 4.802403 5.175505
#> [6,] 4.135294 4.403204 3.965909
#> [7,] 4.531092 4.053405 4.977273
#> [8,] 4.565546 5.166889 4.236111
#> [9,] 4.190756 4.220294 4.138889
#> [10,] 4.231092 4.057410 3.782828
#> [11,] 4.610924 4.170895 4.324495
#> [12,] 4.319328 4.061415 4.099747
#> [13,] 4.167227 4.308411 4.359848
#> [14,] 4.147899 4.257677 4.113636
#> [15,] 4.054622 4.080107 3.625000
#> [16,] 4.296639 4.265688 3.920455
#> GCATGTACACCCATGG-b01 GCCAAATCATGGATGG-b01 GCCTCTAAGCGTAATA-b01
#> [1,] 4.537175 4.335307 4.465791
#> [2,] 4.139405 3.961510 3.898411
#> [3,] 4.311338 4.047372 4.277816
#> [4,] 4.170074 4.332346 4.326883
#> [5,] 4.688662 5.116210 4.489979
#> [6,] 4.295539 3.985196 4.585349
#> [7,] 4.080855 5.173945 4.508639
#> [8,] 5.132900 4.413027 4.557015
#> [9,] 4.428439 3.925241 4.551486
#> [10,] 4.229554 4.032568 4.366966
#> [11,] 4.309480 3.903035 4.487906
#> [12,] 4.550186 4.090303 4.391154
#> [13,] 4.727695 4.445596 4.044229
#> [14,] 4.436803 4.483346 4.573601
#> [15,] 4.480483 4.079941 4.263303
#> [16,] 4.759294 3.948187 4.413960
#> GCCTCTACATGGTAGG-b01 GCGACCAGTAGCTTGT-b01 GCGAGAACAAGCCGCT-b01
#> [1,] 4.533084 4.583429 4.215205
#> [2,] 3.845194 4.244534 4.429240
#> [3,] 4.464419 4.182969 4.127485
#> [4,] 4.217228 4.608170 4.664327
#> [5,] 4.607990 4.839471 4.424561
#> [6,] 4.549313 3.687572 4.122807
#> [7,] 4.470662 4.774453 4.086550
#> [8,] 4.888889 4.422325 5.129825
#> [9,] 4.820225 4.153625 4.287719
#> [10,] 4.431960 4.023590 4.071345
#> [11,] 4.568040 4.403337 4.474854
#> [12,] 4.588015 4.616801 4.210526
#> [13,] 4.118602 4.344074 4.312281
#> [14,] 4.379526 4.563291 4.371930
#> [15,] 4.275905 3.657652 4.192982
#> [16,] 4.580524 4.369390 4.200000
#> GCGAGAACACCAGATT-b01 GCGAGAATCTGTTTGT-b01 GCGCAGTTCCGCTGTT-b01
#> [1,] 4.426306 4.206226 4.625239
#> [2,] 4.084888 3.963424 4.473231
#> [3,] 4.806903 4.185992 4.382409
#> [4,] 4.318097 4.500389 4.419694
#> [5,] 4.357276 4.889494 4.766730
#> [6,] 4.625000 3.979767 4.284895
#> [7,] 4.164179 4.904280 4.309751
#> [8,] 5.030784 4.326070 4.895793
#> [9,] 4.652052 3.885603 4.526769
#> [10,] 4.229478 4.202335 4.212237
#> [11,] 3.971082 4.231907 4.259082
#> [12,] 4.510261 4.267704 4.539197
#> [13,] 3.917910 4.321401 4.615679
#> [14,] 4.127799 4.222568 4.695985
#> [15,] 4.291045 4.183658 3.913958
#> [16,] 4.174440 4.042802 4.293499
#> GCTCCTAAGCCGGTAA-b01 GCTCCTATCTCCTATA-b01 GCTCTGTTCCAACCAA-b01
#> [1,] 4.420035 4.394886 4.404580
#> [2,] 4.079672 4.301136 4.095965
#> [3,] 4.012302 4.517045 4.296619
#> [4,] 4.192736 4.795455 4.163577
#> [5,] 5.031634 4.234375 4.671756
#> [6,] 4.135911 3.968750 4.062159
#> [7,] 4.854130 4.355114 4.029444
#> [8,] 4.671939 4.808239 5.305344
#> [9,] 4.096661 4.958807 4.687023
#> [10,] 4.114821 4.309659 4.098146
#> [11,] 4.114821 4.092330 4.410033
#> [12,] 4.086116 4.639205 4.467830
#> [13,] 4.144112 4.142045 4.585605
#> [14,] 4.404804 4.427557 3.988004
#> [15,] 3.900996 4.036932 4.405671
#> [16,] 3.858817 4.096591 4.045802
#> GCTGCAGCAGCGATCC-b01 GCTGCGACACGGCCAT-b01 GCTGCTTTCACTATTC-b01
#> [1,] 4.211284 4.332577 4.344920
#> [2,] 3.952216 4.563870 3.885027
#> [3,] 4.168682 4.848828 4.338235
#> [4,] 4.306851 4.245654 4.774064
#> [5,] 5.386298 4.681784 4.622995
#> [6,] 4.004030 4.215420 4.152406
#> [7,] 5.074266 4.318216 4.239305
#> [8,] 4.438687 4.774754 5.093583
#> [9,] 3.947611 4.336357 4.594920
#> [10,] 3.840530 4.082389 4.808824
#> [11,] 4.148532 4.390779 4.545455
#> [12,] 4.091537 4.473923 4.597594
#> [13,] 4.273460 4.141345 4.469251
#> [14,] 4.431779 4.121693 4.505348
#> [15,] 3.997697 4.181406 4.278075
#> [16,] 3.998849 4.517007 4.229947
#> GCTGGGTAGGTGACCA-b01 GCTTCCAAGGGATACC-b01 GCTTGAAAGTCTCCTC-b01
#> [1,] 4.323632 4.383033 4.462644
#> [2,] 4.472643 4.021851 4.406609
#> [3,] 4.431898 4.532134 4.251437
#> [4,] 4.111758 4.251928 4.307471
#> [5,] 4.336438 4.643959 4.758621
#> [6,] 4.589057 4.302057 4.262931
#> [7,] 4.239814 4.816195 4.459770
#> [8,] 5.193248 4.997429 4.808908
#> [9,] 4.540163 4.417738 4.086207
#> [10,] 4.221187 4.586118 4.375000
#> [11,] 4.295693 4.638817 4.297414
#> [12,] 4.498254 4.374036 4.433908
#> [13,] 4.842841 4.033419 4.550287
#> [14,] 4.363213 3.760925 3.989943
#> [15,] 4.173458 3.971722 4.254310
#> [16,] 4.301513 4.242931 4.459770
#> GCTTGAACACGGACAA-b01 GCTTGAACACTTAAGC-b01 GCTTGAAGTAATCACC-b01
#> [1,] 4.406793 4.469697 4.116084
#> [2,] 3.684044 4.226010 4.232168
#> [3,] 3.774882 4.455808 4.381818
#> [4,] 3.924171 4.402778 4.556643
#> [5,] 4.895735 4.508838 4.314685
#> [6,] 4.199842 4.117424 3.903497
#> [7,] 4.608215 4.428030 4.337063
#> [8,] 4.404423 4.858586 4.925874
#> [9,] 4.544234 4.569444 4.832168
#> [10,] 4.024487 4.085859 4.053147
#> [11,] 4.168246 3.922980 4.132867
#> [12,] 4.020537 4.063131 4.530070
#> [13,] 4.392575 4.308081 3.960839
#> [14,] 4.407583 4.295455 4.546853
#> [15,] 3.991311 4.093434 4.232168
#> [16,] 3.863349 4.377525 4.401399
#> GCTTGAAGTTCGGGCT-b01 GGAAAGCGTCATGCCG-b01 GGAAAGCTCATAAAGG-b01
#> [1,] 4.344379 4.298013 4.955720
#> [2,] 4.101775 3.638245 4.232472
#> [3,] 4.190533 3.938742 4.088561
#> [4,] 4.246154 4.208609 3.997540
#> [5,] 4.631953 5.270695 4.600246
#> [6,] 4.388166 3.789735 4.159902
#> [7,] 4.474556 5.052980 4.087331
#> [8,] 5.130178 4.071192 4.506765
#> [9,] 4.830769 3.735927 4.538745
#> [10,] 4.233136 3.895695 3.878229
#> [11,] 4.607101 3.917219 4.428044
#> [12,] 4.506509 3.857616 4.226322
#> [13,] 4.417751 4.365894 4.640836
#> [14,] 4.099408 4.409768 4.135301
#> [15,] 4.281657 3.718543 3.897909
#> [16,] 4.420118 3.646523 3.913899
#> GGAACTTAGAAGCCCA-b01 GGAACTTAGATGGGTC-b01 GGAACTTAGGTAGCTG-b01
#> [1,] 4.513680 4.410632 4.179592
#> [2,] 3.708618 3.824015 4.006531
#> [3,] 3.980848 3.980752 3.931429
#> [4,] 4.374145 4.199817 4.262041
#> [5,] 5.156635 5.156737 4.748571
#> [6,] 4.132011 3.891842 3.750204
#> [7,] 4.800958 4.890009 4.769796
#> [8,] 4.401505 4.149404 4.651429
#> [9,] 4.000684 4.150321 4.270204
#> [10,] 4.079343 3.658112 3.861224
#> [11,] 3.720246 3.890926 3.978776
#> [12,] 3.880301 4.021082 3.957551
#> [13,] 4.460328 4.063245 4.154286
#> [14,] 4.132011 4.230981 4.657143
#> [15,] 4.267442 3.890926 3.964082
#> [16,] 4.023940 3.813932 3.867755
#> GGAATAACATGAGCGA-b01 GGAATAATCTTAGCCC-b01 GGACAAGTCCCTCTTT-b01
#> [1,] 4.553879 4.477273 4.227404
#> [2,] 4.265086 4.399522 4.310881
#> [3,] 4.409483 4.374402 4.453656
#> [4,] 4.303879 4.259569 4.027058
#> [5,] 4.703664 4.611244 4.641336
#> [6,] 4.262931 4.586124 4.087507
#> [7,] 4.387931 4.569378 4.498561
#> [8,] 4.716595 5.064593 4.739206
#> [9,] 4.520474 4.450957 4.414508
#> [10,] 4.223060 4.279904 4.414508
#> [11,] 4.160560 4.751196 4.378238
#> [12,] 4.428879 4.342105 4.250432
#> [13,] 4.248922 4.123206 4.373057
#> [14,] 4.427802 4.155502 4.070236
#> [15,] 4.060345 4.466507 4.345423
#> [16,] 4.203664 4.488038 4.418538
#> GGACATTAGCGGATCA-b01 GGACATTTCGATGAGG-b01 GGACGTCAGTCCTCCT-b01
#> [1,] 4.192913 4.491713 4.397485
#> [2,] 4.174803 3.918232 4.147969
#> [3,] 4.580315 4.216575 4.353965
#> [4,] 4.376378 4.651934 4.497099
#> [5,] 4.403150 4.826519 4.591876
#> [6,] 4.592126 3.991160 4.631528
#> [7,] 4.251969 4.432044 4.336557
#> [8,] 4.759843 4.704972 4.990329
#> [9,] 4.670866 4.226519 4.507737
#> [10,] 4.289764 4.030939 4.450677
#> [11,] 4.540945 3.959116 4.626692
#> [12,] 4.440157 3.945856 4.210832
#> [13,] 4.018110 4.323757 4.039652
#> [14,] 4.307874 3.982320 4.416828
#> [15,] 4.470866 3.975691 4.266925
#> [16,] 4.355118 4.040884 4.185687
#> GGACGTCTCATGTCTT-b01 GGACGTCTCCACGTTC-b01 GGAGCAAGTACCGAGA-b01
#> [1,] 4.510695 4.030429 4.719818
#> [2,] 4.173797 4.171508 4.105923
#> [3,] 4.046791 3.857538 4.307517
#> [4,] 4.437166 4.309820 4.143508
#> [5,] 4.939840 5.430152 4.562642
#> [6,] 4.372995 4.195021 4.314351
#> [7,] 4.505348 5.242739 4.679954
#> [8,] 4.991979 4.074689 4.727790
#> [9,] 4.529412 4.399032 4.383827
#> [10,] 4.081551 3.947441 4.251708
#> [11,] 4.356952 3.991701 4.324601
#> [12,] 4.564171 3.964730 4.629841
#> [13,] 4.776738 4.394191 4.136674
#> [14,] 4.229947 4.458506 4.045558
#> [15,] 3.810160 3.713693 4.277904
#> [16,] 4.433155 3.936376 4.435080
#> GGCAATTCAATAGAGT-b01 GGCCGATCAGGGCATA-b01 GGCGACTTCCCTCTTT-b01
#> [1,] 4.514160 4.523632 4.861410
#> [2,] 3.897949 3.628109 4.308244
#> [3,] 4.096191 4.049751 4.047790
#> [4,] 4.089355 3.981343 4.164875
#> [5,] 5.016113 5.257463 4.764636
#> [6,] 3.856934 3.907960 4.474313
#> [7,] 4.575684 4.743781 4.219833
#> [8,] 4.774414 4.548507 4.798088
#> [9,] 4.258789 4.136816 4.403823
#> [10,] 3.920898 3.997512 4.091995
#> [11,] 4.361816 3.998756 4.230585
#> [12,] 3.952637 4.019900 4.328554
#> [13,] 4.483398 4.813433 4.461171
#> [14,] 4.501953 4.340796 4.428913
#> [15,] 3.929688 4.034826 4.097969
#> [16,] 3.890137 3.875622 4.563919
#> GGCGACTTCTATCCTA-b01 GGCGACTTCTTGCCGT-b01 GGCGTGTGTCAGATAA-b01
#> [1,] 4.463985 4.464501 4.376501
#> [2,] 4.094481 4.249097 4.007719
#> [3,] 4.385407 4.038508 4.104631
#> [4,] 4.385407 4.464501 4.177530
#> [5,] 4.434051 4.637786 4.863636
#> [6,] 4.373246 4.303249 4.186964
#> [7,] 4.452760 4.061372 4.512864
#> [8,] 4.825070 5.048135 4.658662
#> [9,] 4.358279 4.306859 4.105489
#> [10,] 4.655753 4.176895 3.871355
#> [11,] 4.278765 4.403129 4.233276
#> [12,] 4.674462 4.170878 3.977702
#> [13,] 4.166511 4.268351 4.039451
#> [14,] 4.297474 4.506619 4.599485
#> [15,] 4.465856 4.127557 3.995712
#> [16,] 3.826006 4.121540 4.578045
#> GGCGTGTTCAAAGTAG-b01 GGCTCGATCATCATTC-b01 GGCTCGATCGAACGGA-b01
#> [1,] 4.363477 4.344585 4.454248
#> [2,] 4.366978 4.323488 4.236383
#> [3,] 4.460910 4.192686 4.297386
#> [4,] 4.167445 4.140647 4.391068
#> [5,] 4.474912 4.496484 4.493464
#> [6,] 4.206534 4.445851 4.351852
#> [7,] 4.214702 4.317862 4.370370
#> [8,] 4.977246 5.042194 5.297386
#> [9,] 4.519253 4.244726 4.540305
#> [10,] 4.159277 4.561181 4.494553
#> [11,] 4.196616 4.324895 4.502179
#> [12,] 4.545508 4.583685 4.223312
#> [13,] 4.458576 4.580872 4.528322
#> [14,] 4.078763 4.160338 4.127451
#> [15,] 4.118436 4.074543 4.305011
#> [16,] 4.504667 4.215190 4.229847
#> GGCTCGATCTTCGAGA-b01 GGGAATGAGCTGCGAA-b01 GGGACCTGTACAAGTA-b01
#> [1,] 4.137230 4.346247 4.535857
#> [2,] 4.000000 4.012107 3.832669
#> [3,] 4.332910 3.915254 4.196547
#> [4,] 4.650572 4.010169 4.233732
#> [5,] 4.687421 5.405811 5.057769
#> [6,] 4.420584 4.074092 3.771580
#> [7,] 4.290978 5.012107 5.084993
#> [8,] 5.228717 4.492010 4.442895
#> [9,] 4.351970 3.910412 3.784861
#> [10,] 4.936468 3.950605 3.855246
#> [11,] 4.578145 4.252300 4.361222
#> [12,] 4.359593 4.041162 4.041169
#> [13,] 4.318933 4.293947 4.313413
#> [14,] 4.496823 4.446489 4.514608
#> [15,] 4.425667 3.798063 3.810757
#> [16,] 4.570521 3.742373 3.931607
#> GGGACCTTCATGTAGC-b01 GGGAGATGTTATCCGA-b01 GGGATGAGTTCGAATC-b01
#> [1,] 4.278595 4.096881 4.462161
#> [2,] 3.776961 4.083610 4.089544
#> [3,] 4.124183 4.082946 4.126516
#> [4,] 4.113562 4.450564 4.395147
#> [5,] 4.740196 5.157930 4.787984
#> [6,] 3.906863 3.964831 3.986713
#> [7,] 4.545752 4.806238 4.525708
#> [8,] 4.558007 4.599867 4.605430
#> [9,] 4.089869 4.358328 4.120739
#> [10,] 3.927288 4.059058 3.996534
#> [11,] 4.084967 4.240212 4.529174
#> [12,] 3.975490 4.122760 4.123628
#> [13,] 4.164216 4.241539 4.233969
#> [14,] 4.521242 4.357001 4.255344
#> [15,] 4.021242 3.712674 4.212594
#> [16,] 3.995915 3.963504 4.098209
#> GGGATGATCTACTTAC-b01 GGGCACTTCAGCTTAG-b01 GGGCATCGTTGTCTTT-b01
#> [1,] 4.302963 4.477337 4.632892
#> [2,] 4.458357 4.120397 4.104443
#> [3,] 4.409167 4.366856 4.084178
#> [4,] 4.721632 3.947592 4.539361
#> [5,] 4.200671 4.793201 5.027280
#> [6,] 4.067077 4.395184 3.946999
#> [7,] 4.234768 4.587819 4.797350
#> [8,] 5.120738 5.089235 4.243959
#> [9,] 5.127446 4.410765 4.190179
#> [10,] 4.249301 4.179887 3.897896
#> [11,] 4.481274 4.135977 4.255651
#> [12,] 4.458916 4.270538 4.187841
#> [13,] 4.138066 4.349858 4.271239
#> [14,] 4.261040 4.347025 4.367888
#> [15,] 4.358301 4.118980 4.031177
#> [16,] 4.334824 4.395184 4.438815
#> GGGCATCTCTGTGCAA-b01 GGTGAAGCACCCATGG-b01 GGTGCGTTCCATGCTC-b01
#> [1,] 4.168591 4.567751 4.314613
#> [2,] 4.167436 3.741192 4.173772
#> [3,] 4.334873 4.018970 4.127021
#> [4,] 4.301386 4.165312 4.575713
#> [5,] 4.496536 4.962060 5.016466
#> [6,] 3.824480 3.941734 3.993825
#> [7,] 4.404157 5.029810 4.756542
#> [8,] 4.833718 4.372629 4.366069
#> [9,] 4.704388 4.199187 4.103793
#> [10,] 4.196305 3.737127 4.152602
#> [11,] 4.204388 4.338753 4.359600
#> [12,] 4.360277 4.230352 4.018230
#> [13,] 4.476905 4.337398 4.206998
#> [14,] 4.612009 4.348238 4.495443
#> [15,] 4.273672 3.875339 4.043223
#> [16,] 4.027714 4.093496 4.004999
#> GGTGTTACATAGGATA-b01 GTAACGTAGCAGCCTC-b01 GTAACGTGTATCTGCA-b01
#> [1,] 4.416370 4.230347 4.384615
#> [2,] 4.091340 3.953077 4.121516
#> [3,] 4.543298 3.696527 4.556299
#> [4,] 4.285884 4.159659 4.566332
#> [5,] 4.488731 5.500305 4.227425
#> [6,] 4.413998 3.735527 4.228540
#> [7,] 4.275208 5.176722 4.559643
#> [8,] 4.901542 4.084704 4.959866
#> [9,] 5.120996 3.881779 4.470457
#> [10,] 4.154211 3.895186 4.275362
#> [11,] 4.422301 4.205972 4.462653
#> [12,] 4.187426 3.981718 4.618729
#> [13,] 4.525504 4.172456 4.678930
#> [14,] 4.481613 4.462523 4.059086
#> [15,] 4.446026 3.570993 4.438127
#> [16,] 4.205219 4.021938 4.346711
#> GTAACTGGTCCAGTGC-b01 GTACGTACAAGTACCT-b01 GTACTTTAGGCTATCT-b01
#> [1,] 4.091414 4.339623 4.598684
#> [2,] 4.126442 4.067925 4.100877
#> [3,] 4.003417 4.420283 4.129386
#> [4,] 4.231098 4.391981 4.445175
#> [5,] 5.163178 4.901887 4.705044
#> [6,] 3.959419 4.037736 4.382675
#> [7,] 5.090132 4.823585 4.152412
#> [8,] 4.434003 4.681604 4.810307
#> [9,] 4.129005 4.344340 4.358553
#> [10,] 4.077745 3.971226 3.916667
#> [11,] 4.357112 4.189151 4.288377
#> [12,] 3.902179 4.092925 4.346491
#> [13,] 4.114054 4.184434 4.692982
#> [14,] 4.596326 4.729717 4.228070
#> [15,] 3.842375 3.994811 4.119518
#> [16,] 3.879111 3.934906 4.040570
#> GTAGGCCGTCTAGCCG-b01 GTAGTCAAGAATGTGT-b01 GTAGTCACATTTCAGG-b01
#> [1,] 4.369048 4.487379 4.220774
#> [2,] 4.208333 4.395146 3.850500
#> [3,] 4.502381 4.360194 3.989570
#> [4,] 4.135714 4.303883 4.206432
#> [5,] 5.166667 4.805825 5.155585
#> [6,] 4.884524 4.446602 3.919600
#> [7,] 4.563095 4.293204 5.033029
#> [8,] 4.888095 5.148544 4.442851
#> [9,] 4.530952 4.413592 4.190787
#> [10,] 4.310714 4.556311 3.985658
#> [11,] 5.038095 4.482524 4.189917
#> [12,] 4.597619 4.264078 4.049109
#> [13,] 3.860714 4.614563 4.121686
#> [14,] 4.670238 4.686408 4.615819
#> [15,] 4.386905 4.036893 3.761408
#> [16,] 4.405952 4.284466 3.896132
#> GTAGTCATCTGAGGGA-b01 GTATCTTAGGGAAACA-b01 GTATCTTGTGAAAGAG-b01
#> [1,] 4.483811 4.560839 4.352825
#> [2,] 4.052729 4.481119 4.190287
#> [3,] 4.461610 4.553846 4.178394
#> [4,] 4.158187 4.123077 4.082260
#> [5,] 4.935245 4.539860 4.830525
#> [6,] 4.717854 4.173427 3.986125
#> [7,] 4.569843 4.455944 4.327056
#> [8,] 4.912118 4.781818 4.632309
#> [9,] 4.723404 4.565035 4.394450
#> [10,] 4.236818 4.118881 4.079286
#> [11,] 4.703053 4.254545 4.019822
#> [12,] 4.289547 4.356643 4.404361
#> [13,] 3.977798 4.653147 4.380575
#> [14,] 4.047179 4.120280 4.333994
#> [15,] 4.004625 4.124476 4.199207
#> [16,] 4.606846 4.345455 3.989098
#> GTATTCTTCCAGGGCT-b01 GTATTCTTCGGCGCTA-b01 GTCAAGTTCTTGAGAC-b01
#> [1,] 4.527443 4.578440 4.499293
#> [2,] 4.234270 4.038563 4.008487
#> [3,] 4.597055 4.368098 3.995757
#> [4,] 4.444444 4.194566 4.373409
#> [5,] 4.720214 4.663453 4.322489
#> [6,] 4.552878 4.747590 4.957567
#> [7,] 4.496653 4.245399 4.164074
#> [8,] 4.809906 5.210342 4.964639
#> [9,] 4.175368 4.789658 4.572843
#> [10,] 4.084337 4.523225 4.393211
#> [11,] 4.697456 4.829097 4.131542
#> [12,] 4.708166 4.226117 4.500707
#> [13,] 4.155288 3.998247 4.548798
#> [14,] 4.585007 4.488168 4.920792
#> [15,] 4.303882 4.303243 4.304102
#> [16,] 4.448461 4.341805 4.550212
#> GTCACAAAGCACACAG-b01 GTCACAATCGCGTTTC-b01 GTCACGGGTAGCGATG-b01
#> [1,] 4.364282 4.273232 4.525892
#> [2,] 3.960934 4.339112 4.062140
#> [3,] 3.980213 3.740985 4.612198
#> [4,] 4.502283 4.012829 4.052934
#> [5,] 5.118721 5.364771 4.515535
#> [6,] 4.000507 4.007628 4.981588
#> [7,] 4.950279 4.623093 4.308400
#> [8,] 4.514460 4.655687 5.143843
#> [9,] 4.233891 3.946949 5.021864
#> [10,] 3.990360 4.005895 4.467204
#> [11,] 4.246575 4.403606 4.891830
#> [12,] 3.918316 3.911234 4.456847
#> [13,] 4.276509 4.390777 4.383199
#> [14,] 4.633688 4.859917 4.439586
#> [15,] 3.888382 3.714979 4.292290
#> [16,] 4.066464 4.151179 4.181818
#> GTCATTTGTACCGTTA-b01 GTCCTCACACAAGCCC-b01 GTCCTCAGTAAGGGCT-b01
#> [1,] 4.039269 4.355043 4.465278
#> [2,] 4.366210 3.941210 4.729167
#> [3,] 4.358904 4.193660 3.813889
#> [4,] 4.550685 4.346398 4.583333
#> [5,] 4.987215 5.247262 4.522222
#> [6,] 4.021005 4.015562 4.518056
#> [7,] 4.569863 5.115274 4.387500
#> [8,] 4.402740 4.483573 4.761111
#> [9,] 4.262100 4.084726 4.305556
#> [10,] 4.074886 3.966571 4.481944
#> [11,] 4.519635 4.172911 4.140278
#> [12,] 3.996347 3.931412 4.412500
#> [13,] 4.063014 4.243228 4.516667
#> [14,] 4.659361 4.491066 4.233333
#> [15,] 4.023744 3.922190 3.801389
#> [16,] 3.924201 4.038617 4.155556
#> GTCGTAAGTCTAAACC-b01 GTCTCGTCAGACGCCT-b01 GTCTCGTTCGAGAACG-b01
#> [1,] 4.219980 4.412155 4.293299
#> [2,] 4.764884 4.036464 3.817010
#> [3,] 4.336024 3.929282 3.937629
#> [4,] 4.174571 4.362431 4.072165
#> [5,] 4.385469 4.853039 5.342784
#> [6,] 4.162462 3.817680 3.992268
#> [7,] 4.246216 4.833149 5.179381
#> [8,] 5.081736 4.496133 4.347423
#> [9,] 5.010091 4.271823 4.022165
#> [10,] 4.710394 3.930387 4.011340
#> [11,] 4.168517 4.004420 4.211340
#> [12,] 4.198789 4.131492 4.062371
#> [13,] 4.247225 4.209945 4.222165
#> [14,] 4.419778 4.874033 4.418041
#> [15,] 4.617558 3.984530 3.943299
#> [16,] 4.169526 4.248619 3.876804
#> GTCTTCGCAAGGCTCC-b01 GTCTTCGTCTATCGCC-b01 GTGAAGGAGCTAAGAT-b01
#> [1,] 4.451001 4.526012 4.452575
#> [2,] 4.272919 4.294798 4.119241
#> [3,] 4.712329 3.919075 4.386179
#> [4,] 4.425711 4.403179 4.239837
#> [5,] 4.593256 4.508671 4.724932
#> [6,] 4.211802 4.013006 3.959350
#> [7,] 4.085353 4.326590 4.449864
#> [8,] 4.973656 4.687861 4.514905
#> [9,] 4.318230 4.365607 3.876694
#> [10,] 4.402529 4.563584 4.224932
#> [11,] 4.327713 4.232659 4.349593
#> [12,] 4.141201 4.209538 4.330623
#> [13,] 4.623815 4.859827 4.084011
#> [14,] 4.224447 4.164740 4.260163
#> [15,] 4.191781 3.921965 4.108401
#> [16,] 4.033720 4.328035 4.151762
#> GTGAAGGTCAGTTGAC-b01 GTGAAGGTCCTACAGA-b01 GTGCAGCAGAATTCCC-b01
#> [1,] 4.190014 4.515487 4.483357
#> [2,] 4.044383 3.516593 4.234443
#> [3,] 4.099861 3.595133 4.272069
#> [4,] 4.361997 4.133850 4.273517
#> [5,] 4.671290 5.063053 4.228654
#> [6,] 4.155340 3.595133 4.218524
#> [7,] 4.485437 4.950221 4.489146
#> [8,] 4.979196 4.439159 5.082489
#> [9,] 4.489598 4.209071 4.713459
#> [10,] 4.180305 3.741150 4.371925
#> [11,] 4.128988 3.622788 4.241679
#> [12,] 4.077670 3.969027 4.441389
#> [13,] 4.506241 4.224558 4.551375
#> [14,] 4.359223 4.438053 4.600579
#> [15,] 4.156727 3.678097 4.043415
#> [16,] 4.158114 3.955752 4.617945
#> GTGCATACAAGTCATC-b01 GTGCATATCTTGTATC-b01 GTGCGGTAGCGTAATA-b01
#> [1,] 4.563202 4.550096 4.324061
#> [2,] 4.060393 3.832370 4.542420
#> [3,] 4.120787 4.053950 4.628651
#> [4,] 3.841292 4.700385 4.821975
#> [5,] 5.248596 5.221580 4.570236
#> [6,] 3.589888 3.744701 4.389430
#> [7,] 4.546348 4.874759 4.104312
#> [8,] 4.526685 4.074181 5.055633
#> [9,] 3.896067 4.192678 4.376912
#> [10,] 3.936798 4.094412 4.162726
#> [11,] 3.997191 4.134875 4.660640
#> [12,] 4.105337 4.039499 4.428373
#> [13,] 4.257022 4.159923 4.524339
#> [14,] 4.174157 4.315029 4.257302
#> [15,] 3.938202 4.170520 4.525730
#> [16,] 3.880618 4.129094 4.453408
#> GTGCGGTTCTGTACGA-b01 GTGCTTCAGCGCTTAT-b01 GTGGGTCTCGGCGGTT-b01
#> [1,] 4.463983 4.493842 4.430328
#> [2,] 4.468220 4.162562 4.064208
#> [3,] 4.264831 4.216749 4.344262
#> [4,] 4.307203 4.060345 4.165301
#> [5,] 4.516949 4.810345 4.883880
#> [6,] 4.448093 4.316502 4.114754
#> [7,] 3.927966 4.280788 4.601093
#> [8,] 5.045551 5.009852 4.397541
#> [9,] 4.445975 4.905172 4.321038
#> [10,] 4.171610 4.273399 3.890710
#> [11,] 4.231992 4.359606 3.995902
#> [12,] 4.567797 4.410099 4.185792
#> [13,] 4.204449 4.742611 4.375683
#> [14,] 4.457627 4.025862 4.461749
#> [15,] 4.014831 4.216749 4.017760
#> [16,] 4.413136 4.201970 4.088798
#> GTGTGCGAGTGTTAGA-b01 GTGTTAGCACCTATCC-b01 GTGTTAGCACGCCAGT-b01
#> [1,] 4.171061 4.413986 4.497976
#> [2,] 4.213505 4.591608 3.904858
#> [3,] 4.188424 4.665734 4.360324
#> [4,] 4.424437 4.633566 4.462551
#> [5,] 4.877170 4.591608 4.604251
#> [6,] 4.199357 4.194406 4.238866
#> [7,] 4.720900 4.289510 4.286437
#> [8,] 4.600000 4.756643 5.315789
#> [9,] 4.286174 4.511888 4.437247
#> [10,] 4.254019 4.370629 4.121457
#> [11,] 4.338264 4.282517 4.358300
#> [12,] 4.081029 4.325874 4.324899
#> [13,] 4.234084 4.096503 4.491903
#> [14,] 4.639228 4.163636 4.325911
#> [15,] 3.992926 4.202797 4.139676
#> [16,] 4.185209 4.367832 4.037449
#> GTGTTAGCATACCATG-b01 GTTAAGCCAAGCCATT-b01 GTTCATTGTCTCCACT-b01
#> [1,] 4.348036 4.437226 4.229551
#> [2,] 4.064653 3.939416 4.340369
#> [3,] 4.232628 4.069343 4.547493
#> [4,] 4.230816 4.154745 4.178100
#> [5,] 4.933535 5.033577 4.291557
#> [6,] 3.804834 3.914599 4.521108
#> [7,] 4.725076 4.855474 4.063325
#> [8,] 4.732931 4.377372 5.124011
#> [9,] 4.211480 4.207299 5.005277
#> [10,] 4.214502 3.834307 4.505277
#> [11,] 4.135347 4.276642 4.241425
#> [12,] 4.351057 4.256934 4.525066
#> [13,] 4.204230 4.375182 3.887863
#> [14,] 4.378248 4.293431 4.310026
#> [15,] 3.687009 4.116058 4.394459
#> [16,] 4.097281 4.001460 4.335092
#> GTTCTCGGTCCAGTGC-b01 GTTCTCGTCTCGATGA-b01 TAAGAGAGTCCTCTTG-b01
#> [1,] 4.358832 4.283307 4.348736
#> [2,] 4.114047 4.303371 3.914079
#> [3,] 4.657858 4.464687 3.910108
#> [4,] 4.550765 4.218299 4.004693
#> [5,] 4.641168 4.495987 5.272563
#> [6,] 4.244784 4.075441 3.809747
#> [7,] 3.923505 4.158909 5.198917
#> [8,] 5.140473 4.764045 4.301805
#> [9,] 4.677330 4.439005 4.005415
#> [10,] 4.196106 4.431782 3.967148
#> [11,] 4.300417 4.256822 4.184477
#> [12,] 4.567455 4.763242 3.861733
#> [13,] 4.297636 4.281701 4.285560
#> [14,] 4.870654 4.341091 4.632852
#> [15,] 3.848401 4.105136 3.673646
#> [16,] 4.312935 4.314607 3.702888
#> TAAGAGATCGATCCCT-b01 TAAGCGTAGCGAAGGG-b01 TAAGCGTTCAGAGACG-b01
#> [1,] 4.269578 4.353073 4.515931
#> [2,] 4.241576 3.834637 4.432598
#> [3,] 4.517323 4.397765 4.552696
#> [4,] 4.392027 4.474860 4.334559
#> [5,] 4.797817 4.956425 4.437500
#> [6,] 3.962506 4.050279 3.952206
#> [7,] 4.485050 4.861453 4.535539
#> [8,] 4.596108 4.330726 4.914216
#> [9,] 4.087328 4.439106 4.530637
#> [10,] 4.186521 3.800000 4.024510
#> [11,] 4.243949 4.090503 4.234069
#> [12,] 4.269103 4.203352 4.183824
#> [13,] 4.308970 4.145251 4.564951
#> [14,] 4.515425 4.386592 4.243873
#> [15,] 4.011391 4.195531 4.209559
#> [16,] 4.146179 3.860335 4.137255
#> TAAGTGCCATACGCCG-b01 TAAGTGCGTAACGACG-b01 TAAGTGCTCATTTGGG-b01
#> [1,] 3.922710 4.670222 4.398931
#> [2,] 4.241412 3.901333 4.211932
#> [3,] 4.391221 3.927111 4.351736
#> [4,] 4.385496 4.203556 4.109528
#> [5,] 4.207061 4.957333 4.926981
#> [6,] 4.544847 3.974222 3.896705
#> [7,] 4.480916 4.765333 4.555654
#> [8,] 4.885496 4.238222 4.373108
#> [9,] 4.556298 4.177778 4.266251
#> [10,] 4.376908 3.632889 4.090828
#> [11,] 4.568702 4.408889 4.388246
#> [12,] 4.338740 4.133333 4.137133
#> [13,] 4.306298 4.278222 4.601959
#> [14,] 4.213740 4.507556 4.197685
#> [15,] 4.068702 3.766222 3.942119
#> [16,] 4.536260 3.921778 4.357970
#> TAAGTGCTCGTAGGAG-b01 TACACGACAGACGCAA-b01 TACAGTGTCGAGCCCA-b01
#> [1,] 4.221294 4.665877 4.528857
#> [2,] 4.055324 3.552133 4.144876
#> [3,] 4.488518 3.811611 4.248528
#> [4,] 4.365344 4.359005 4.474676
#> [5,] 4.662839 5.201422 4.594817
#> [6,] 4.245303 3.559242 4.150766
#> [7,] 4.295407 4.906398 4.257951
#> [8,] 4.767223 4.306872 5.420495
#> [9,] 4.281837 4.309242 4.550059
#> [10,] 4.225470 3.738152 4.532391
#> [11,] 4.168058 3.592417 4.706714
#> [12,] 4.553236 3.792654 4.585395
#> [13,] 4.562630 4.276066 4.413428
#> [14,] 3.886221 4.119668 4.285041
#> [15,] 4.549061 3.549763 4.257951
#> [16,] 4.007307 3.459716 4.136631
#> TACCTATCAATCAGAA-b01 TACCTATGTAGAAGGA-b01 TACCTATGTTATGTGC-b01
#> [1,] 4.361970 4.541667 4.594051
#> [2,] 4.211913 4.127083 4.139068
#> [3,] 4.477663 4.326042 4.540193
#> [4,] 4.096220 4.296354 4.491158
#> [5,] 4.654066 4.551562 4.823955
#> [6,] 4.261168 4.110937 4.221865
#> [7,] 4.185567 4.235937 4.506431
#> [8,] 4.948454 4.828646 4.565916
#> [9,] 4.507446 4.810417 3.893891
#> [10,] 4.178694 4.344792 4.159164
#> [11,] 4.531501 4.537500 4.454180
#> [12,] 4.529210 4.470833 3.918810
#> [13,] 4.350515 4.230208 4.136656
#> [14,] 4.223368 4.220833 4.375402
#> [15,] 4.045819 4.368750 4.152733
#> [16,] 4.355097 4.308854 4.382637
#> TACCTATTCACCTTAT-b01 TACGGGCGTACAGCAG-b01 TACGGTAGTAAGCACG-b01
#> [1,] 4.477117 4.469251 4.427429
#> [2,] 4.296339 4.204545 4.110857
#> [3,] 4.331808 4.438503 4.432000
#> [4,] 4.315789 4.409091 4.350857
#> [5,] 4.676201 4.197861 4.357714
#> [6,] 4.251716 4.294118 4.065143
#> [7,] 4.100686 4.216578 4.217143
#> [8,] 5.072082 5.140374 5.144000
#> [9,] 4.629291 4.466578 4.706286
#> [10,] 4.402746 4.104278 3.859429
#> [11,] 4.355835 4.352941 4.276571
#> [12,] 4.193364 4.314171 4.356571
#> [13,] 4.548055 4.121658 4.296000
#> [14,] 4.297483 4.554813 4.153143
#> [15,] 4.040046 4.346257 4.254857
#> [16,] 4.426773 4.012032 3.858286
#> TACGGTATCCTAAGTG-b01 TACTCATGTTGCGCAC-b01 TACTCGCGTAAGGGAA-b01
#> [1,] 4.247079 4.427015 4.617964
#> [2,] 4.061856 4.544662 4.489820
#> [3,] 4.484192 4.697168 4.311377
#> [4,] 4.428179 4.529412 4.166467
#> [5,] 4.885223 4.295207 4.558084
#> [6,] 3.926460 4.234205 4.441916
#> [7,] 4.659794 4.227669 4.483832
#> [8,] 4.594845 4.998911 4.657485
#> [9,] 4.091409 4.520697 4.571257
#> [10,] 4.025086 4.436819 4.293413
#> [11,] 4.302749 4.599129 4.452695
#> [12,] 4.159107 4.313725 4.243114
#> [13,] 4.176632 4.271242 4.576048
#> [14,] 4.505155 4.430283 4.311377
#> [15,] 4.174227 4.196078 4.147305
#> [16,] 4.227835 3.910675 4.674251
#> TACTCGCGTCCAAGTT-b01 TACTCGCTCTACCAGA-b01 TACTTACTCATCGGAT-b01
#> [1,] 4.454774 4.517551 4.731148
#> [2,] 4.016332 4.299592 3.604372
#> [3,] 4.685930 4.095510 4.075410
#> [4,] 4.133166 4.266939 4.163934
#> [5,] 4.783920 4.423673 5.315847
#> [6,] 4.293970 3.809796 3.839344
#> [7,] 4.056533 4.578776 4.746448
#> [8,] 5.376884 4.586939 4.313661
#> [9,] 4.498744 4.715102 3.745355
#> [10,] 4.582915 3.928163 3.679781
#> [11,] 4.561558 4.345306 4.080874
#> [12,] 4.521357 4.182041 4.260109
#> [13,] 4.667085 4.316735 3.987978
#> [14,] 4.097990 4.347755 4.543169
#> [15,] 4.145729 3.613878 3.532240
#> [16,] 3.940955 4.109388 3.700546
#> TACTTGTGTGATAAGT-b01 TAGACCAGTCTGATCA-b01 TAGACCATCCACGTTC-b01
#> [1,] 4.219495 4.582849 4.531346
#> [2,] 4.353436 4.131541 3.841727
#> [3,] 4.390603 4.510901 4.297020
#> [4,] 4.603787 4.512355 4.400822
#> [5,] 4.421459 4.336483 4.720452
#> [6,] 4.476157 4.369913 3.989723
#> [7,] 4.028752 4.281977 4.645427
#> [8,] 5.357644 5.251453 4.601233
#> [9,] 4.820477 4.592297 4.406989
#> [10,] 4.589060 4.473837 3.853032
#> [11,] 4.300842 4.309593 4.021583
#> [12,] 4.440393 4.452035 4.138746
#> [13,] 4.208976 4.667878 4.297020
#> [14,] 4.609397 4.473110 4.295992
#> [15,] 4.468443 4.042151 3.970195
#> [16,] 4.450912 4.172238 3.992806
#> TAGAGCTAGTGAAGAG-b01 TAGAGCTGTCGGCTCA-b01 TAGAGCTTCCAACCAA-b01
#> [1,] 4.411361 4.293276 4.598734
#> [2,] 4.020911 4.135908 4.436709
#> [3,] 4.051498 4.005722 4.400000
#> [4,] 4.482834 4.482117 4.322785
#> [5,] 4.948814 4.583691 4.549367
#> [6,] 3.880774 4.230329 4.350633
#> [7,] 4.755618 4.364807 4.382278
#> [8,] 4.479089 5.097282 5.156962
#> [9,] 4.342385 4.608011 4.827848
#> [10,] 3.850499 3.992847 4.362025
#> [11,] 4.153558 4.389127 4.487342
#> [12,] 4.207241 4.640916 4.598734
#> [13,] 4.111735 4.371960 4.396203
#> [14,] 4.506242 4.243205 4.107595
#> [15,] 3.914482 4.018598 4.136709
#> [16,] 3.899813 4.154506 4.537975
#> TAGCCGGTCAAACCGT-b01 TAGGCATAGGCACATG-b01 TAGGCATGTAGCGTGA-b01
#> [1,] 4.687936 4.083176 4.383580
#> [2,] 4.004985 4.069994 4.029610
#> [3,] 4.538385 4.143440 4.261104
#> [4,] 4.534397 4.173886 4.222073
#> [5,] 4.527418 5.193032 4.523553
#> [6,] 3.911266 4.239171 3.788694
#> [7,] 4.423729 4.889517 4.481830
#> [8,] 4.940179 4.247332 4.892328
#> [9,] 4.076770 4.202134 4.582773
#> [10,] 4.371884 4.169805 4.215343
#> [11,] 4.342971 4.139046 4.378197
#> [12,] 4.241276 4.008161 4.499327
#> [13,] 4.116650 4.188010 4.849260
#> [14,] 4.143569 4.547395 4.008075
#> [15,] 4.032901 3.964218 4.069987
#> [16,] 4.078764 4.040176 4.141319
#> TAGGCATGTCCAAGTT-b01 TAGTGGTGTTACTGAC-b01 TAGTTGGGTCACTTCC-b01
#> [1,] 4.464045 4.544362 4.401909
#> [2,] 4.095506 3.403882 3.789976
#> [3,] 3.900000 4.095194 4.053938
#> [4,] 4.396629 4.204251 4.331742
#> [5,] 4.525843 4.524030 5.462530
#> [6,] 3.764045 3.729205 4.006205
#> [7,] 4.250562 4.733826 4.995227
#> [8,] 4.547191 4.149723 4.158473
#> [9,] 4.397753 4.188540 4.132697
#> [10,] 3.892135 3.729205 4.093556
#> [11,] 3.916854 3.933457 4.194749
#> [12,] 4.211236 3.999076 4.127924
#> [13,] 4.311236 4.014787 4.282100
#> [14,] 4.408989 4.409427 4.293079
#> [15,] 3.929213 4.207948 4.051551
#> [16,] 4.103371 4.171904 4.135084
#> TAGTTGGTCCTAGTGA-b01 TATCAGGAGTACGTTC-b01 TATCAGGTCACTGGGC-b01
#> [1,] 4.338225 4.528416 4.489796
#> [2,] 3.772561 4.250302 4.170686
#> [3,] 3.938371 4.713422 4.418367
#> [4,] 4.258988 4.238210 4.418367
#> [5,] 5.134996 4.163241 4.889610
#> [6,] 3.864270 4.407497 4.846939
#> [7,] 5.010271 4.342201 4.400742
#> [8,] 4.423331 5.077388 4.785714
#> [9,] 3.925899 4.380895 4.467532
#> [10,] 3.686720 4.174123 4.573284
#> [11,] 4.168745 4.542926 4.778293
#> [12,] 4.082905 4.655381 4.395176
#> [13,] 4.415260 4.532044 4.276438
#> [14,] 4.242847 4.118501 4.548237
#> [15,] 3.975789 4.210399 4.430427
#> [16,] 3.831988 4.238210 4.228200
#> TATCTCAGTAAGTTCC-b01 TATCTCATCGGCGCTA-b01 TATTACCGTGACTCAT-b01
#> [1,] 4.421416 4.333333 4.150954
#> [2,] 4.236615 4.260417 3.969136
#> [3,] 4.234024 4.516026 3.683502
#> [4,] 4.328152 4.370192 4.232323
#> [5,] 4.535406 4.364583 5.478114
#> [6,] 4.189119 3.967147 3.907407
#> [7,] 4.435233 4.478365 5.473625
#> [8,] 4.639896 4.864583 4.484287
#> [9,] 4.449050 4.195513 3.736251
#> [10,] 4.119171 4.092949 3.714366
#> [11,] 4.227116 4.319712 4.037598
#> [12,] 4.287565 4.194712 3.858025
#> [13,] 4.202936 4.297276 4.068462
#> [14,] 4.347150 4.358173 4.589787
#> [15,] 4.120898 4.141827 3.709315
#> [16,] 4.137306 4.456731 3.703143
#> TCAACGAAGCAACGGT-b01 TCAACGATCGTATCAG-b01 TCAATCTCAGCCAGAA-b01
#> [1,] 4.261634 4.425272 4.530075
#> [2,] 4.206825 4.286685 4.368421
#> [3,] 4.249224 4.292120 4.337093
#> [4,] 3.978283 4.351902 4.189223
#> [5,] 4.321613 4.316576 4.769424
#> [6,] 3.945191 4.341033 4.364662
#> [7,] 4.371251 4.351902 4.368421
#> [8,] 4.956567 5.137228 5.181704
#> [9,] 4.409514 4.661685 4.627820
#> [10,] 4.228542 4.538043 4.399749
#> [11,] 4.091003 4.357337 4.234336
#> [12,] 4.620476 4.354620 4.601504
#> [13,] 4.471562 4.436141 4.482456
#> [14,] 3.842813 4.444293 4.299499
#> [15,] 4.403309 4.123641 4.184211
#> [16,] 4.445708 4.293478 4.206767
#> TCACAAGAGGGCTCTC-b01 TCACAAGCACGTGAGA-b01 TCACAAGTCACTGGGC-b01
#> [1,] 4.209929 4.275081 4.340000
#> [2,] 4.736170 4.091694 4.331765
#> [3,] 4.707801 4.423948 4.444706
#> [4,] 4.097872 4.372168 4.350588
#> [5,] 4.258156 4.560949 4.304706
#> [6,] 3.936170 4.053937 4.332941
#> [7,] 3.970213 4.184466 4.315294
#> [8,] 5.306383 4.902913 4.947059
#> [9,] 4.482270 4.718447 4.347059
#> [10,] 3.947518 4.335491 4.363529
#> [11,] 4.368794 4.201726 4.231765
#> [12,] 4.519149 4.470334 4.231765
#> [13,] 4.485106 4.275081 4.564706
#> [14,] 4.390071 4.165049 4.132941
#> [15,] 4.014184 4.115426 3.860000
#> [16,] 4.382979 4.555556 4.282353
#> TCACAAGTCGCAGGCT-b01 TCACGAAAGGGCATGT-b01 TCACGAATCGTCTGAA-b01
#> [1,] 4.233978 4.373810 4.492973
#> [2,] 3.966747 4.352381 3.863784
#> [3,] 4.334341 4.591667 4.446486
#> [4,] 4.222491 4.379762 4.203243
#> [5,] 4.991536 4.675000 5.203243
#> [6,] 4.169287 4.345238 3.715676
#> [7,] 4.975816 4.345238 4.847568
#> [8,] 4.558041 4.676190 4.614054
#> [9,] 4.356711 4.683333 4.405405
#> [10,] 4.117291 4.317857 4.036757
#> [11,] 4.118501 4.454762 4.362162
#> [12,] 3.983071 4.433333 4.153514
#> [13,] 4.174123 4.635714 4.251892
#> [14,] 4.299274 4.085714 4.207568
#> [15,] 3.950423 4.307143 4.340541
#> [16,] 4.052600 4.551190 4.320000
#> TCAGCAACAGGTGCCT-b01 TCAGCAACATCCAACA-b01 TCAGCAAGTCCATCCT-b01
#> [1,] 4.312195 4.484407 4.317460
#> [2,] 4.503659 3.586279 4.445767
#> [3,] 4.800000 3.914761 4.575397
#> [4,] 4.217073 4.048857 4.436508
#> [5,] 4.597561 5.191268 4.322751
#> [6,] 4.052439 3.773389 4.074074
#> [7,] 4.336585 5.519751 4.154762
#> [8,] 5.076829 4.208940 5.149471
#> [9,] 4.729268 4.240125 4.708995
#> [10,] 4.313415 3.722453 4.173280
#> [11,] 4.174390 4.174636 4.070106
#> [12,] 4.335366 3.971933 4.367725
#> [13,] 4.620732 4.217256 4.202381
#> [14,] 4.091463 4.520790 4.428571
#> [15,] 4.026829 3.417879 4.145503
#> [16,] 4.363415 3.644491 4.203704
#> TCAGCTCCAAGAGGCT-b01 TCAGCTCCAATGTTGC-b01 TCAGCTCGTTGGACCC-b01
#> [1,] 4.343842 3.937673 4.681628
#> [2,] 3.876839 4.570637 3.643006
#> [3,] 4.135771 4.211911 4.153445
#> [4,] 4.357713 4.457064 3.974948
#> [5,] 5.073560 4.349030 4.907098
#> [6,] 4.057587 4.160665 4.035491
#> [7,] 4.773014 4.407202 4.674322
#> [8,] 4.358134 5.132964 4.521921
#> [9,] 4.197982 4.670360 4.028184
#> [10,] 3.963430 4.038781 3.721294
#> [11,] 4.066835 4.480609 4.498956
#> [12,] 4.175704 4.389197 4.130480
#> [13,] 4.127785 4.429363 4.074113
#> [14,] 4.329550 4.578947 4.413361
#> [15,] 4.100042 4.340720 3.923800
#> [16,] 3.917192 4.040166 3.945720
#> TCAGGATGTTATTCTC-b01 TCAGGATTCAAAGACA-b01 TCAGGATTCAATAAGG-b01
#> [1,] 4.245913 4.381998 4.378734
#> [2,] 4.223433 4.260154 3.836320
#> [3,] 4.065395 4.418222 4.265233
#> [4,] 4.380109 4.223930 4.261649
#> [5,] 5.015668 4.522503 4.771804
#> [6,] 4.000000 4.209660 4.391876
#> [7,] 4.869210 4.125137 4.573477
#> [8,] 4.554496 5.053787 4.733572
#> [9,] 4.435286 4.421515 4.161290
#> [10,] 3.978883 4.121844 4.371565
#> [11,] 4.113079 4.409440 4.517324
#> [12,] 4.004768 4.380900 4.266428
#> [13,] 4.348774 4.290889 4.480287
#> [14,] 4.538828 4.293085 4.001195
#> [15,] 3.767711 4.282108 3.921147
#> [16,] 3.922343 4.350165 4.120669
#> TCAGGTAGTACCGGCT-b01 TCATTACGTAGGGTAC-b01 TCATTACGTCGTCTTC-b01
#> [1,] 4.745086 4.274433 4.188873
#> [2,] 3.979154 3.991400 4.055637
#> [3,] 4.054795 4.106333 4.364568
#> [4,] 4.055986 4.143862 4.366032
#> [5,] 4.833830 4.935106 5.062225
#> [6,] 4.039309 3.994527 4.168375
#> [7,] 4.037522 4.970289 4.454612
#> [8,] 5.005956 4.539484 4.880673
#> [9,] 4.608100 4.451916 4.305271
#> [10,] 4.058964 3.916341 4.636164
#> [11,] 4.129839 4.352619 4.325769
#> [12,] 4.043478 4.098514 4.249634
#> [13,] 5.025015 4.108679 4.409956
#> [14,] 4.142347 4.877248 4.322108
#> [15,] 3.740917 3.838937 4.136164
#> [16,] 4.408577 3.882721 4.005857
#> TCATTACTCCCACTTG-b01 TCGCGAGAGAGATGAG-b01 TCGCGAGCAACTGGCC-b01
#> [1,] 4.217787 4.480000 4.435096
#> [2,] 4.238178 4.153103 3.757212
#> [3,] 4.182213 4.103448 3.925481
#> [4,] 4.102386 4.186207 4.238582
#> [5,] 4.976139 4.484138 5.122596
#> [6,] 3.912798 4.212414 4.020433
#> [7,] 4.841649 4.200000 4.953726
#> [8,] 4.539696 4.913103 4.248798
#> [9,] 4.200868 4.434483 3.972957
#> [10,] 3.967462 3.980690 3.804087
#> [11,] 4.255965 4.255172 4.097356
#> [12,] 4.245553 4.235862 4.022837
#> [13,] 4.364859 4.478621 4.143630
#> [14,] 4.376573 4.143448 4.407452
#> [15,] 3.936659 4.135172 4.034255
#> [16,] 4.017354 4.263448 3.819111
#> TCGGGACAGGCGACAT-b01 TCGGGACTCCCTAATT-b01 TCGGTAACAGCTGGCT-b01
#> [1,] 4.351175 4.396459 4.664234
#> [2,] 3.906005 3.675905 3.743309
#> [3,] 3.943864 4.088145 3.850365
#> [4,] 4.096606 4.416474 4.276156
#> [5,] 5.561358 5.363356 4.715328
#> [6,] 3.734987 4.048499 3.690998
#> [7,] 4.913838 5.061586 4.486618
#> [8,] 4.472585 4.415319 4.200730
#> [9,] 4.026110 4.026174 4.282238
#> [10,] 3.712794 3.839492 3.591241
#> [11,] 3.781984 3.994611 3.620438
#> [12,] 3.819843 3.769053 4.038929
#> [13,] 4.353786 4.086990 4.563260
#> [14,] 4.326371 4.386836 4.104623
#> [15,] 3.806789 3.881062 3.962287
#> [16,] 3.870757 3.841032 3.806569
#> TCGGTAACATAAAGGT-b01 TCGGTAATCCAATGGT-b01 TCGTACCAGCAAATCA-b01
#> [1,] 4.506901 4.464917 4.741100
#> [2,] 3.686324 4.294590 3.806904
#> [3,] 3.986198 4.341457 4.418554
#> [4,] 4.303639 4.284681 3.792880
#> [5,] 4.805521 4.444296 4.468177
#> [6,] 3.996236 4.295394 4.318231
#> [7,] 4.205772 4.143010 4.399137
#> [8,] 4.631117 4.950723 4.699029
#> [9,] 4.173149 4.585163 4.354908
#> [10,] 3.830615 4.334762 4.108954
#> [11,] 4.465496 4.241296 4.496224
#> [12,] 4.010038 4.370380 4.406688
#> [13,] 4.071518 4.592126 4.319310
#> [14,] 4.141782 4.126138 4.096009
#> [15,] 4.227102 4.121853 3.912621
#> [16,] 3.836888 4.487145 4.066882
#> TCGTACCCATTGAGCT-b01 TCGTAGACACAAGACG-b01 TCGTAGAGTGACGCCT-b01
#> [1,] 4.352865 4.202429 4.247379
#> [2,] 3.889323 4.469636 3.975891
#> [3,] 4.244792 3.939721 4.190776
#> [4,] 4.401042 4.100315 4.350629
#> [5,] 4.772135 5.219073 4.962788
#> [6,] 4.074219 3.588394 4.124214
#> [7,] 4.661458 4.757985 4.614780
#> [8,] 4.600260 4.857850 4.370021
#> [9,] 4.278646 4.020243 4.043501
#> [10,] 3.751302 3.913630 4.028826
#> [11,] 4.035156 4.242465 4.192872
#> [12,] 3.930990 3.958614 3.908281
#> [13,] 4.296875 4.059379 4.370545
#> [14,] 4.139323 4.720198 4.609539
#> [15,] 4.182292 3.822762 3.889413
#> [16,] 3.993490 3.987854 3.998952
#> TCTCATACAAGAAAGG-b01 TCTCATATCTGCGGCA-b01 TCTGGAACATTCGACA-b01
#> [1,] 4.489655 4.257951 4.349504
#> [2,] 4.013793 4.172261 4.048512
#> [3,] 4.256158 4.301678 4.280044
#> [4,] 4.658128 4.425353 4.296582
#> [5,] 4.707389 5.012367 4.931643
#> [6,] 3.761576 3.998233 3.785006
#> [7,] 4.403941 4.835247 5.085998
#> [8,] 4.977340 4.723940 4.491731
#> [9,] 4.319212 4.356007 4.174201
#> [10,] 3.744828 4.034452 3.974642
#> [11,] 3.998030 4.292845 4.152150
#> [12,] 4.159606 4.026060 3.823594
#> [13,] 4.590148 3.979682 4.450937
#> [14,] 4.403941 4.538869 4.484013
#> [15,] 4.156650 3.926237 3.810364
#> [16,] 3.939901 4.163869 4.111356
#> TCTGGAAGTAAGTAGT-b01 TCTTCGGCAGGGAGAG-b01 TCTTTCCAGCGTGAAC-b01
#> [1,] 4.344081 4.635207 4.465314
#> [2,] 3.437440 4.213150 4.804319
#> [3,] 3.889798 4.343584 4.230366
#> [4,] 4.580366 4.268293 4.535340
#> [5,] 5.109240 4.375398 4.361911
#> [6,] 3.940327 4.019088 4.361911
#> [7,] 5.088065 4.162248 4.336387
#> [8,] 4.298364 5.347826 4.899215
#> [9,] 4.252166 4.267232 4.353403
#> [10,] 4.025505 3.943796 4.258508
#> [11,] 3.885948 4.128314 4.354058
#> [12,] 3.881136 4.353128 4.319372
#> [13,] 4.146776 4.411453 4.199607
#> [14,] 4.455727 4.449629 4.398560
#> [15,] 3.849374 3.704136 4.094241
#> [16,] 3.716554 4.129374 3.994764
#> TCTTTCCAGTGTACGG-b01 TCTTTCCGTCCGTGAC-b01 TGAAAGAAGTACGACG-b01
#> [1,] 4.067204 4.293967 4.283660
#> [2,] 4.084677 3.990831 4.487582
#> [3,] 4.049059 4.206308 4.500654
#> [4,] 4.327285 4.250871 4.337255
#> [5,] 5.165323 4.959839 4.345098
#> [6,] 3.754704 3.940767 4.430065
#> [7,] 5.015457 4.820466 4.128105
#> [8,] 4.391129 4.346048 4.695425
#> [9,] 3.910618 4.047313 4.440523
#> [10,] 3.876344 3.999266 4.284967
#> [11,] 4.133737 4.302402 4.228758
#> [12,] 4.062500 4.096094 4.484967
#> [13,] 4.299059 4.202274 4.156863
#> [14,] 4.399866 4.433890 4.177778
#> [15,] 3.922715 3.882267 4.351634
#> [16,] 4.372312 3.996516 4.368627
#> TGAAAGACATATGAGA-b01 TGAAAGACATCGATGT-b01 TGAAAGATCCCTCAGT-b01
#> [1,] 4.127601 4.253879 4.326720
#> [2,] 4.545076 4.131171 4.337260
#> [3,] 4.241331 4.276446 4.232486
#> [4,] 4.421637 4.661495 4.404216
#> [5,] 4.128988 4.133992 4.512089
#> [6,] 4.004161 3.860367 4.239306
#> [7,] 4.195562 4.610719 4.393056
#> [8,] 5.246879 4.857546 4.907006
#> [9,] 4.764216 4.334274 4.354619
#> [10,] 4.377254 4.605078 4.116553
#> [11,] 4.499307 4.428773 4.160570
#> [12,] 4.324549 4.647391 4.300062
#> [13,] 4.366158 4.622003 4.208927
#> [14,] 4.701803 4.352609 4.342839
#> [15,] 4.212205 4.448519 4.039678
#> [16,] 4.145631 4.380818 4.019839
#> TGACAACAGTGGAGTC-b01 TGACAACCACATCCAA-b01 TGACAACTCTATCCCG-b01
#> [1,] 4.606316 4.276451 4.627520
#> [2,] 3.837895 4.030717 3.730938
#> [3,] 4.273684 4.249147 4.241017
#> [4,] 4.313684 4.060296 3.974584
#> [5,] 5.060000 4.542662 5.134969
#> [6,] 4.149474 3.968146 3.954426
#> [7,] 4.798947 4.549488 4.687117
#> [8,] 4.290526 5.222981 4.219982
#> [9,] 3.873684 4.431172 3.985101
#> [10,] 4.148421 4.060296 3.952673
#> [11,] 4.207368 4.485779 4.082384
#> [12,] 4.033684 4.316268 4.035057
#> [13,] 4.313684 4.370876 4.156004
#> [14,] 4.096842 4.191126 4.387379
#> [15,] 4.111579 4.040956 3.940403
#> [16,] 4.437895 4.259386 4.333918
#> TGACTAGGTCCCGACA-b01 TGACTAGTCGGCATCG-b01 TGACTTTCATGTCTCC-b01
#> [1,] 4.233662 4.424561 4.572344
#> [2,] 3.973142 4.047953 4.390110
#> [3,] 4.132498 4.076023 4.161172
#> [4,] 4.054611 4.405848 4.273810
#> [5,] 5.067144 4.723977 4.680403
#> [6,] 4.230976 4.408187 4.467033
#> [7,] 4.952551 4.407018 4.275641
#> [8,] 4.445837 4.580117 4.880037
#> [9,] 4.528201 4.347368 4.547619
#> [10,] 4.278424 4.389474 4.590659
#> [11,] 4.134288 4.126316 4.491758
#> [12,] 3.989257 4.318129 4.277473
#> [13,] 4.087735 4.581287 4.518315
#> [14,] 4.599821 4.307602 4.231685
#> [15,] 4.024172 4.067836 4.306777
#> [16,] 4.206804 4.271345 4.362637
#> TGACTTTGTCGCGTGT-b01 TGACTTTTCCACGCAG-b01 TGAGCATAGGCATGGT-b01
#> [1,] 4.434097 4.035519 4.372139
#> [2,] 3.931232 4.196721 4.121393
#> [3,] 4.143266 4.493169 4.631841
#> [4,] 4.147564 4.000000 4.111443
#> [5,] 4.737822 4.300546 4.513433
#> [6,] 4.305158 4.459016 4.344279
#> [7,] 4.935530 4.095628 4.473632
#> [8,] 4.414040 5.110656 4.968159
#> [9,] 3.891117 4.561475 4.261692
#> [10,] 4.310888 4.463115 4.215920
#> [11,] 3.981375 4.028689 4.280597
#> [12,] 4.124642 4.435792 4.383085
#> [13,] 4.173352 4.383880 4.361194
#> [14,] 4.234957 4.607923 4.272637
#> [15,] 3.985673 4.106557 4.465672
#> [16,] 3.893983 4.687158 4.166169
#> TGAGCATGTATGAAAC-b01 TGAGCCGTCAACGAAA-b01 TGAGGGAAGTATCGAA-b01
#> [1,] 4.498160 4.690423 4.524496
#> [2,] 4.161148 3.853007 4.365994
#> [3,] 4.155261 4.010022 4.710375
#> [4,] 4.303900 4.085746 4.211816
#> [5,] 4.467991 4.771715 4.380403
#> [6,] 4.211921 3.880846 4.413545
#> [7,] 4.466519 4.757238 4.262248
#> [8,] 4.990434 4.534521 5.028818
#> [9,] 4.715968 4.269488 4.325648
#> [10,] 4.285504 3.934298 4.533141
#> [11,] 4.417954 4.074610 4.690202
#> [12,] 4.215600 4.213808 4.515850
#> [13,] 4.515820 4.500000 4.332853
#> [14,] 4.207506 4.053452 4.115274
#> [15,] 4.288447 3.974388 4.184438
#> [16,] 4.401030 3.742762 4.142651
#> TGATTTCGTCGCATCG-b01 TGATTTCTCCAGAAGG-b01 TGCACCTAGGTAGCCA-b01
#> [1,] 3.989691 4.295105 4.318458
#> [2,] 3.596793 4.349650 4.323529
#> [3,] 4.117984 4.388811 4.203854
#> [4,] 4.246277 4.097902 4.125761
#> [5,] 4.902635 4.718881 4.653144
#> [6,] 4.184422 4.262937 4.105477
#> [7,] 4.933562 4.193007 4.034483
#> [8,] 4.514318 5.134266 5.131846
#> [9,] 3.902635 4.423776 4.356998
#> [10,] 4.263459 4.255944 4.360041
#> [11,] 4.166094 4.286713 4.319473
#> [12,] 4.187858 4.272727 4.746450
#> [13,] 4.198167 4.693706 4.541582
#> [14,] 4.413517 4.131469 3.748479
#> [15,] 3.813288 3.892308 4.081136
#> [16,] 4.002291 4.365035 4.649087
#> TGCCCATAGCTAAACA-b01 TGCCCATAGGAATCGC-b01 TGCCCATGTGATGTGG-b01
#> [1,] 4.188976 4.311787 4.543605
#> [2,] 4.492126 4.283270 4.531977
#> [3,] 4.332021 4.319392 4.655039
#> [4,] 4.538058 4.542776 4.609496
#> [5,] 4.426509 4.569392 4.151163
#> [6,] 4.347769 4.554183 4.218023
#> [7,] 4.136483 4.129278 4.442829
#> [8,] 4.832021 5.368821 4.941860
#> [9,] 4.565617 4.449620 4.759690
#> [10,] 4.185039 4.469582 4.395349
#> [11,] 4.475066 4.632129 4.197674
#> [12,] 4.250656 4.235741 4.511628
#> [13,] 4.152231 4.093156 4.324612
#> [14,] 4.503937 4.359316 4.535853
#> [15,] 4.293963 4.590304 4.073643
#> [16,] 4.160105 4.110266 4.308140
#> TGCCCATTCTTGTACT-b01 TGCCCTAAGTTGAGTA-b01 TGCCCTATCGCTTAGA-b01
#> [1,] 4.910690 4.415746 4.708128
#> [2,] 4.871448 4.399171 4.115764
#> [3,] 4.024357 4.656077 4.030788
#> [4,] 4.358593 4.479282 4.222906
#> [5,] 4.236806 4.624309 4.805419
#> [6,] 4.395129 4.189227 3.966749
#> [7,] 4.204330 4.417127 4.380542
#> [8,] 5.138024 5.250000 4.625616
#> [9,] 4.079838 4.560773 4.402709
#> [10,] 4.263870 4.296961 3.933498
#> [11,] 4.543978 4.186464 4.052956
#> [12,] 4.435724 4.848066 4.507389
#> [13,] 4.621110 4.294199 4.681034
#> [14,] 4.062246 4.490331 3.947044
#> [15,] 3.787551 4.200276 4.502463
#> [16,] 4.104195 4.345304 4.354680
#> TGCCCTATCTACTCAT-b01 TGCGGGTAGAGACTAT-b01 TGCGGGTAGTAACCCT-b01
#> [1,] 4.649550 4.706414 4.540951
#> [2,] 3.545946 3.998193 3.858653
#> [3,] 4.133333 3.999097 3.897622
#> [4,] 4.738739 4.278229 4.376486
#> [5,] 5.035135 4.713640 5.164465
#> [6,] 4.058559 3.652213 3.932629
#> [7,] 4.794595 4.412827 4.950462
#> [8,] 4.417117 4.452575 4.781374
#> [9,] 4.070270 4.075881 4.554822
#> [10,] 3.925225 3.776874 3.894320
#> [11,] 4.515315 4.173442 4.315059
#> [12,] 4.109910 3.866305 4.091810
#> [13,] 4.033333 4.315266 4.155878
#> [14,] 4.075676 4.407407 4.382431
#> [15,] 3.911712 4.090334 3.894320
#> [16,] 3.560360 3.826558 3.898283
#> TGCGGGTTCCGCTGTT-b01 TGCGGGTTCGGACAAG-b01 TGCGTGGAGAGCCCAA-b01
#> [1,] 4.343238 4.590234 4.655104
#> [2,] 4.290984 3.910828 3.839445
#> [3,] 4.178279 3.973815 4.242815
#> [4,] 4.409836 4.154989 4.361744
#> [5,] 4.581967 4.791932 4.759167
#> [6,] 3.961066 4.254069 4.054509
#> [7,] 4.238730 4.406228 4.581764
#> [8,] 4.746926 4.610757 4.192270
#> [9,] 4.836066 4.106865 4.293360
#> [10,] 4.250000 3.987261 3.904856
#> [11,] 4.394467 4.497523 4.209118
#> [12,] 4.439549 4.404812 4.273538
#> [13,] 4.633197 4.252654 4.228940
#> [14,] 4.459016 4.266100 4.362735
#> [15,] 4.204918 4.079972 3.919722
#> [16,] 4.462090 4.130219 3.896928
#> TGCGTGGTCGACAGCC-b01 TGCTACCGTCAATACC-b01 TGCTACCGTTAAGACA-b01
#> [1,] 4.121604 4.451864 4.010503
#> [2,] 4.701164 4.511408 4.280570
#> [3,] 4.530401 4.169171 3.996999
#> [4,] 4.335058 4.230940 4.306827
#> [5,] 4.345408 4.520868 5.167292
#> [6,] 4.331177 4.352254 3.950488
#> [7,] 4.368693 4.381191 5.171793
#> [8,] 4.776197 4.947691 4.881470
#> [9,] 4.904269 4.554257 4.359340
#> [10,] 4.662354 3.997218 4.049512
#> [11,] 4.269082 4.170284 4.435859
#> [12,] 4.322122 4.476349 3.934734
#> [13,] 4.394567 4.580412 4.108027
#> [14,] 4.381630 4.329438 4.764441
#> [15,] 4.755498 4.178631 3.578395
#> [16,] 4.014230 4.348915 3.945236
#> TGGACGCGTCGAGTTT-b01 TGGACGCGTGGTAACG-b01 TGGCGCAGTGCCTTGG-b01
#> [1,] 4.367128 4.563677 4.717241
#> [2,] 4.186244 4.476262 4.351724
#> [3,] 4.439035 4.165787 4.427586
#> [4,] 4.334078 4.250188 4.211494
#> [5,] 4.310406 4.399397 4.713793
#> [6,] 4.415364 4.712133 4.332184
#> [7,] 4.320232 3.921628 4.436782
#> [8,] 4.944618 5.164280 4.900000
#> [9,] 4.323805 4.188395 4.472414
#> [10,] 4.273336 4.373775 4.062069
#> [11,] 4.338991 4.414469 4.294253
#> [12,] 4.272890 4.605124 4.452874
#> [13,] 4.393926 4.407687 4.557471
#> [14,] 4.138008 4.385079 4.287356
#> [15,] 4.179098 3.952524 4.074713
#> [16,] 4.216168 4.265260 4.437931
#> TGGGAAGCATGCCCGA-b01 TGGGAAGGTGCCTGCA-b01 TGGGAAGTCGGACAAG-b01
#> [1,] 4.250765 4.428931 4.226196
#> [2,] 4.415902 3.566038 3.772354
#> [3,] 4.462793 3.920755 4.115515
#> [4,] 4.419980 4.216352 4.246979
#> [5,] 4.598369 4.723270 5.212180
#> [6,] 4.445464 3.938365 3.969551
#> [7,] 4.020387 4.718239 5.264862
#> [8,] 5.246687 4.334591 4.497825
#> [9,] 4.377166 4.245283 4.323828
#> [10,] 4.608563 3.900629 4.117931
#> [11,] 4.566769 4.465409 4.191880
#> [12,] 4.629969 4.057862 3.867569
#> [13,] 4.145770 4.330818 4.116965
#> [14,] 4.168196 4.318239 4.387144
#> [15,] 4.446483 3.828931 3.992750
#> [16,] 4.298675 4.289308 3.998067
#> TGGGCGTCAGTCGATT-b01 TGGTTAGAGGAGTTGC-b01 TGGTTAGAGTCAAGCG-b01
#> [1,] 4.381901 4.242594 4.294914
#> [2,] 4.016889 4.115679 4.265852
#> [3,] 4.161079 4.147089 4.503963
#> [4,] 4.289640 4.338100 4.257266
#> [5,] 4.898160 4.910878 4.753963
#> [6,] 3.965213 3.890449 4.277411
#> [7,] 4.826569 4.895301 4.536658
#> [8,] 4.648097 4.587079 4.512880
#> [9,] 4.030502 4.195863 4.284676
#> [10,] 4.078397 4.165730 4.158190
#> [11,] 4.041341 4.321502 4.202114
#> [12,] 4.304260 4.171859 4.056473
#> [13,] 4.196622 4.105720 4.299207
#> [14,] 4.357197 4.446374 4.530053
#> [15,] 3.962944 3.995403 4.092801
#> [16,] 4.135115 4.085546 4.076618
#> TGGTTAGCAAGCCATT-b01 TGGTTAGCACGCGAAA-b01 TGGTTAGCAGACAGGT-b01
#> [1,] 4.637465 4.417752 4.308965
#> [2,] 4.161696 4.226384 4.209178
#> [3,] 4.275396 4.539902 4.430096
#> [4,] 4.140727 4.268730 4.083244
#> [5,] 4.726468 4.817590 4.702241
#> [6,] 4.487884 4.552932 4.038420
#> [7,] 4.077353 4.275244 4.036286
#> [8,] 5.158434 5.292345 5.247599
#> [9,] 4.572227 4.528502 4.530950
#> [10,] 4.229730 4.179153 4.292423
#> [11,] 4.318733 4.216612 4.273212
#> [12,] 4.242777 4.184039 4.221985
#> [13,] 4.669152 4.473941 4.673959
#> [14,] 4.274930 4.290717 4.239594
#> [15,] 4.153308 4.084691 3.940768
#> [16,] 4.293569 4.615635 4.328175
#> TGGTTAGTCGCATGGC-b01 TGTCCCAAGAATAGGG-b01 TGTCCCAGTTCATGGT-b01
#> [1,] 4.229025 3.793333 4.344379
#> [2,] 4.378685 4.045333 3.868639
#> [3,] 4.369615 4.248000 3.984615
#> [4,] 4.353741 4.261333 4.324260
#> [5,] 4.787982 4.264000 4.817751
#> [6,] 4.422902 4.020000 4.164497
#> [7,] 4.528345 4.429333 4.568047
#> [8,] 4.959184 4.969333 4.501775
#> [9,] 4.320862 4.593333 4.421302
#> [10,] 4.360544 4.368000 4.273373
#> [11,] 4.459184 4.601333 4.216568
#> [12,] 4.840136 4.646667 3.944379
#> [13,] 4.198413 4.352000 4.356213
#> [14,] 4.243764 4.001333 4.473373
#> [15,] 4.538549 4.228000 3.927811
#> [16,] 4.335601 4.352000 4.098225
#> TGTGGTAAGGGTTCCC-b01 TGTGTTTCAAGCTGTT-b01 TGTGTTTTCGGATGTT-b01
#> [1,] 4.556615 4.464680 4.565056
#> [2,] 3.612634 4.213024 4.066171
#> [3,] 4.048868 4.458057 4.364312
#> [4,] 4.244338 4.364238 4.193309
#> [5,] 4.959476 4.161148 5.194796
#> [6,] 4.101311 4.391832 3.809665
#> [7,] 4.768772 4.399558 4.794052
#> [8,] 4.135876 5.027594 4.607435
#> [9,] 4.255066 4.495585 4.373978
#> [10,] 3.929678 4.421634 3.951673
#> [11,] 4.275328 4.715232 4.182900
#> [12,] 3.929678 4.666667 3.963569
#> [13,] 4.380215 4.151214 4.269888
#> [14,] 4.524434 4.208609 4.755390
#> [15,] 3.873659 4.269316 3.835688
#> [16,] 3.973778 4.189845 3.962825
#> TGTTCCGGTCAGCTAT-b01 TTAACTCAGTTTGCGT-b01 TTAACTCGTGCGAAAC-b01
#> [1,] 4.304274 4.211288 4.409897
#> [2,] 3.797525 4.202605 3.539683
#> [3,] 3.827897 4.192475 3.844071
#> [4,] 4.493251 4.192475 4.125117
#> [5,] 5.169854 4.694645 5.380952
#> [6,] 4.143982 4.231548 3.958917
#> [7,] 4.853768 4.409551 4.860878
#> [8,] 4.291339 4.144718 4.070962
#> [9,] 4.475253 4.118669 4.086835
#> [10,] 4.053993 4.173661 3.895425
#> [11,] 4.053993 3.966715 3.897292
#> [12,] 4.183352 4.247467 3.960784
#> [13,] 4.208661 3.997106 4.592904
#> [14,] 4.257030 4.590449 4.319328
#> [15,] 3.930259 4.028944 3.779645
#> [16,] 4.053431 4.221418 3.836601
#> TTAGGACAGTACATGA-b01 TTAGGCACACATGGGA-b01 TTCCCAGTCAGCGACC-b01
#> [1,] 4.249541 4.425824 4.503731
#> [2,] 4.247706 4.655220 4.021370
#> [3,] 4.006116 4.252747 4.123474
#> [4,] 4.351682 4.717033 4.386364
#> [5,] 4.954128 4.634615 4.577341
#> [6,] 3.803058 4.048077 4.056988
#> [7,] 4.777982 4.494505 4.190977
#> [8,] 4.647706 4.748626 5.047151
#> [9,] 4.138226 4.763736 4.325305
#> [10,] 3.877064 4.259615 4.170285
#> [11,] 4.228746 4.350275 4.171981
#> [12,] 3.889908 4.575549 4.195387
#> [13,] 4.083792 4.241758 4.471506
#> [14,] 4.800612 4.667582 4.120081
#> [15,] 3.771254 4.729396 4.188602
#> [16,] 3.917431 4.409341 4.313433
#> TTCGAAGAGCTACCGC-b01 TTCGAAGCACTGAAGG-b01 TTCGAAGCATTCCTGC-b01
#> [1,] 4.403137 4.326241 4.296296
#> [2,] 3.934502 4.364066 4.287933
#> [3,] 3.940959 4.069740 4.416965
#> [4,] 4.481550 4.237589 4.437276
#> [5,] 5.048893 4.530733 4.365591
#> [6,] 3.786900 4.111111 4.221027
#> [7,] 4.738007 4.479905 4.436081
#> [8,] 4.289668 4.715721 5.075269
#> [9,] 4.239852 4.301418 4.581840
#> [10,] 3.882841 4.198582 4.292712
#> [11,] 4.053506 4.387707 4.513740
#> [12,] 4.036900 4.361702 4.400239
#> [13,] 4.244465 4.270095 4.240143
#> [14,] 4.490775 4.169031 4.338112
#> [15,] 4.069188 3.856383 3.720430
#> [16,] 3.856089 4.360520 4.371565
#> TTCGGTCCAGGGTATG-b01 TTCGGTCGTCTTGTCC-b01 TTCGGTCGTTGGTGGA-b01
#> [1,] 4.26875 4.448945 4.309686
#> [2,] 4.22625 4.378209 4.316508
#> [3,] 4.36500 4.487165 4.256480
#> [4,] 4.42500 4.403879 4.597544
#> [5,] 4.51500 4.427838 4.457026
#> [6,] 3.94000 4.147176 4.517053
#> [7,] 4.50250 4.404450 4.010914
#> [8,] 4.69250 4.747290 5.287858
#> [9,] 4.56875 4.711922 4.742156
#> [10,] 4.20625 4.304050 4.144611
#> [11,] 4.61000 4.347404 4.263302
#> [12,] 4.62250 4.390188 4.226467
#> [13,] 4.25500 4.419852 4.521146
#> [14,] 4.44500 4.181403 4.002729
#> [15,] 4.21250 3.986309 4.392906
#> [16,] 4.55875 4.295493 4.525239
#> TTCTACACAGTCGATT-b01 TTGAACGAGTACATGA-b01 TTGAACGCACCAGGTC-b01
#> [1,] 4.207317 4.281001 4.458426
#> [2,] 4.180710 4.258248 4.023282
#> [3,] 4.080931 4.695108 4.158537
#> [4,] 4.913525 4.308305 4.297118
#> [5,] 4.342572 4.824801 4.707317
#> [6,] 4.373614 4.775882 4.077051
#> [7,] 4.115299 4.357224 4.726718
#> [8,] 4.997783 5.003413 4.546563
#> [9,] 4.737251 4.501706 4.365854
#> [10,] 4.341463 4.254835 4.134146
#> [11,] 4.203991 4.415245 4.307650
#> [12,] 4.279379 4.191126 4.458426
#> [13,] 4.549889 4.406143 4.309867
#> [14,] 4.677384 4.309443 4.328160
#> [15,] 4.525499 4.393629 4.105322
#> [16,] 4.068736 4.360637 4.054878
#> TTGAACGGTCTAACGT-b01 TTGACTTAGCTAGTTC-b01 TTGACTTCAATCTACG-b01
#> [1,] 4.574512 4.249789 4.482604
#> [2,] 4.089414 4.734177 4.432099
#> [3,] 3.956835 4.168776 4.187430
#> [4,] 4.442960 4.155274 4.026936
#> [5,] 4.707091 4.926582 4.570146
#> [6,] 4.095581 3.647257 3.927048
#> [7,] 4.459404 4.226160 3.997755
#> [8,] 4.450154 5.215190 4.950617
#> [9,] 4.414183 4.179747 4.456790
#> [10,] 3.780062 4.032068 4.126824
#> [11,] 4.389517 4.551899 4.104377
#> [12,] 4.067831 3.972996 4.167228
#> [13,] 4.262076 3.983122 4.757576
#> [14,] 4.278520 4.953586 4.301908
#> [15,] 4.031860 3.724895 3.764310
#> [16,] 4.006166 4.329958 4.176207
#> TTGACTTGTCTGGTCG-b01 TTGCCGTAGATATGCA-b01 TTTATGCAGACACTAA-b01
#> [1,] 4.078067 4.861624 4.577531
#> [2,] 4.608426 3.491697 4.053833
#> [3,] 4.311029 3.958487 3.968403
#> [4,] 4.286245 4.090406 4.191340
#> [5,] 4.843866 5.202952 4.519602
#> [6,] 4.268897 3.884686 4.304272
#> [7,] 4.767038 4.857934 4.614980
#> [8,] 4.942999 4.262915 4.819778
#> [9,] 4.501859 3.995387 4.651258
#> [10,] 4.434944 3.892066 4.275015
#> [11,] 4.356877 4.327491 4.139848
#> [12,] 4.337051 4.307196 4.262727
#> [13,] 4.366791 4.448339 4.210064
#> [14,] 4.183395 4.184502 4.471036
#> [15,] 4.408922 3.730627 3.929783
#> [16,] 4.107807 3.668819 4.308953
#> TTTATGCCAGTTAACC-b01 AAAGTAGCAACACCTA-b02 AAAGTAGGTTCAGACT-b02
#> [1,] 4.360406 4.623188 4.259494
#> [2,] 4.331218 4.320158 4.388608
#> [3,] 4.678934 4.548090 4.384810
#> [4,] 4.347716 4.125165 4.303797
#> [5,] 4.255076 4.565217 4.263291
#> [6,] 4.421320 4.084321 3.940506
#> [7,] 4.261421 4.367589 4.434177
#> [8,] 5.118020 5.032938 5.481013
#> [9,] 4.365482 4.527009 4.456962
#> [10,] 4.421320 4.111989 4.165823
#> [11,] 4.144670 4.206851 4.091139
#> [12,] 4.392132 4.197628 4.308861
#> [13,] 4.145939 4.127800 4.308861
#> [14,] 4.795685 4.142292 4.021519
#> [15,] 4.394670 4.295125 4.268354
#> [16,] 4.378173 4.222661 4.416456
#> AACTCCCAGGTCGGAT-b02 AACTTTCGTACACCGC-b02 AAGACCTAGGCTCAGA-b02
#> [1,] 4.396159 4.308000 4.065943
#> [2,] 4.220484 4.093333 4.071373
#> [3,] 4.251067 4.065333 3.826998
#> [4,] 4.448080 4.466667 4.100853
#> [5,] 4.487909 4.573333 5.176106
#> [6,] 4.165007 4.756000 3.904577
#> [7,] 4.645804 3.997333 5.066718
#> [8,] 4.838549 4.936000 4.435997
#> [9,] 4.121622 4.196000 3.960434
#> [10,] 4.324324 4.686667 3.734678
#> [11,] 3.983642 4.561333 4.274631
#> [12,] 4.054765 4.561333 3.954228
#> [13,] 4.229018 4.213333 4.136540
#> [14,] 4.071124 4.857333 4.373933
#> [15,] 4.115932 4.562667 4.052754
#> [16,] 4.236131 4.388000 4.130334
#> ACACCCTGTCTTGCGG-b02 ACAGCCGAGCGATATA-b02 ACCAGTAGTCATCGGC-b02
#> [1,] 4.050132 4.023834 4.187209
#> [2,] 4.668865 4.388601 4.708140
#> [3,] 4.391821 4.396891 4.489535
#> [4,] 4.587071 4.149223 4.458140
#> [5,] 4.150396 4.321244 3.862791
#> [6,] 3.915567 3.810363 3.851163
#> [7,] 4.428760 4.406218 3.779070
#> [8,] 5.336412 5.019689 5.087209
#> [9,] 4.646438 4.380311 5.397674
#> [10,] 4.163588 4.090155 4.913953
#> [11,] 4.226913 4.165803 4.310465
#> [12,] 4.217678 4.305699 4.159302
#> [13,] 4.237467 4.292228 4.456977
#> [14,] 4.515831 4.163731 4.203488
#> [15,] 4.584433 4.153368 4.973256
#> [16,] 4.265172 4.198964 3.943023
#> ACGATGTGTAATAGCA-b02 ACGGGTCTCAGTCAGT-b02 ACTGAGTTCTTGTATC-b02
#> [1,] 4.339174 4.421271 4.560399
#> [2,] 4.423029 4.417127 4.511831
#> [3,] 4.345432 4.457182 4.047323
#> [4,] 4.695870 3.881215 4.373599
#> [5,] 4.178974 4.321823 4.655044
#> [6,] 4.070088 4.277624 4.226650
#> [7,] 4.053817 4.294199 4.521793
#> [8,] 5.454318 4.877072 4.885430
#> [9,] 4.619524 4.294199 4.429639
#> [10,] 4.163955 4.343923 4.246575
#> [11,] 4.043805 4.803867 4.560399
#> [12,] 4.239049 4.698895 4.495641
#> [13,] 4.541927 3.918508 4.560399
#> [14,] 4.395494 4.008287 4.465753
#> [15,] 4.051314 4.215470 3.834371
#> [16,] 4.314143 4.412983 4.149440
#> ACTGATGCAAGCGATG-b02 ACTTACTAGGGTGTTG-b02 ACTTGTTGTGGCCCTA-b02
#> [1,] 4.537747 4.474623 4.318480
#> [2,] 4.109175 4.241427 4.031455
#> [3,] 4.033682 4.238683 4.220183
#> [4,] 4.435540 4.127572 4.001311
#> [5,] 4.321719 4.289438 4.369594
#> [6,] 4.225319 4.488340 4.148100
#> [7,] 4.545877 4.057613 3.963303
#> [8,] 5.279907 5.102881 5.224115
#> [9,] 4.533101 4.868313 4.399738
#> [10,] 4.365854 4.200274 3.888598
#> [11,] 4.117305 4.216735 4.173001
#> [12,] 4.552846 4.655693 4.129751
#> [13,] 4.331010 4.127572 4.605505
#> [14,] 4.466899 4.311385 4.474443
#> [15,] 4.484321 4.290809 3.950197
#> [16,] 4.576074 4.271605 4.564875
#> AGCTCCTGTTATTCTC-b02 AGCTCCTTCAGCTCTC-b02 AGCTTGATCTTGCAAG-b02
#> [1,] 4.301587 4.507328 4.481986
#> [2,] 4.282313 4.153326 4.313851
#> [3,] 4.512472 4.641488 4.175340
#> [4,] 4.134921 4.266065 4.497198
#> [5,] 4.527211 4.633596 4.690152
#> [6,] 3.958050 4.121759 4.021617
#> [7,] 4.202948 4.499436 4.210568
#> [8,] 5.198413 4.508455 4.842274
#> [9,] 4.216553 4.354002 4.361089
#> [10,] 4.168934 4.264938 3.963971
#> [11,] 4.053288 4.020293 4.123299
#> [12,] 4.456916 4.346110 4.028823
#> [13,] 4.357143 4.409245 4.458767
#> [14,] 3.933107 4.305524 4.021617
#> [15,] 4.587302 4.614431 4.165733
#> [16,] 4.040816 4.332582 3.817454
#> AGGTCATCACACCGCA-b02 AGTAGTCGTCGAATCT-b02 ATAACGCGTATGGTTC-b02
#> [1,] 4.638498 4.456160 4.149754
#> [2,] 4.119718 3.965594 4.428571
#> [3,] 4.046948 3.924528 4.610837
#> [4,] 4.511737 3.938957 4.134975
#> [5,] 4.708920 4.321865 4.282759
#> [6,] 3.884194 4.668147 3.641379
#> [7,] 4.416275 3.957825 4.301478
#> [8,] 4.737089 5.107658 5.413793
#> [9,] 4.266823 4.580466 4.323153
#> [10,] 3.917058 3.840178 4.132020
#> [11,] 4.253521 3.900111 4.409852
#> [12,] 4.203443 4.049945 4.144828
#> [13,] 4.276213 4.489456 3.988177
#> [14,] 4.158059 4.544950 3.904433
#> [15,] 4.258216 3.918979 4.411823
#> [16,] 4.077465 4.483907 4.440394
#> ATCATGGGTCTAGTGT-b02 ATCATGGTCATGTCCC-b02 ATCCGAAGTGGCTCCA-b02
#> [1,] 4.262937 4.443640 4.489140
#> [2,] 4.282517 3.841779 3.952215
#> [3,] 4.125874 3.845915 4.248480
#> [4,] 4.337063 4.721820 4.432667
#> [5,] 4.013986 4.721820 4.718506
#> [6,] 4.177622 4.142709 4.185056
#> [7,] 3.991608 4.411582 4.591659
#> [8,] 5.434965 4.717684 4.739357
#> [9,] 4.914685 4.113754 4.494353
#> [10,] 4.539860 3.920372 3.993918
#> [11,] 4.327273 4.110651 4.066898
#> [12,] 4.162238 4.009307 4.163336
#> [13,] 4.646154 4.395036 4.162467
#> [14,] 4.432168 4.227508 4.381407
#> [15,] 4.917483 4.022751 4.348393
#> [16,] 4.247552 4.116856 4.155517
#> ATCGAGTGTCATCGGC-b02 ATCTGCCCATCCCACT-b02 ATTGGACCATTCACTT-b02
#> [1,] 4.229630 3.966278 4.665025
#> [2,] 4.134259 4.535668 4.076355
#> [3,] 4.274074 4.284047 4.231527
#> [4,] 4.500926 4.377432 4.307882
#> [5,] 4.489815 4.125811 4.596880
#> [6,] 3.946296 3.830091 4.194581
#> [7,] 4.548148 4.342412 4.483580
#> [8,] 5.012037 5.326848 5.153530
#> [9,] 3.778704 4.511025 4.413793
#> [10,] 4.381481 3.998703 4.201970
#> [11,] 4.408333 4.007782 4.401478
#> [12,] 4.373148 4.202335 4.279967
#> [13,] 4.206481 4.542153 4.305419
#> [14,] 4.280556 4.107652 4.194581
#> [15,] 4.214815 4.285344 4.402299
#> [16,] 4.243519 4.540856 4.133826
#> ATTGGACGTTCCACGG-b02 ATTTCTGCAACGATCT-b02 ATTTCTGGTATTAGCC-b02
#> [1,] 4.444025 3.954491 4.167127
#> [2,] 4.200000 4.150898 4.098066
#> [3,] 4.179874 4.314970 4.312155
#> [4,] 4.189937 4.252695 4.462707
#> [5,] 5.060377 4.706587 4.523481
#> [6,] 4.262893 3.743713 4.410221
#> [7,] 4.605031 4.813174 4.106354
#> [8,] 5.044025 4.674251 5.357735
#> [9,] 4.342138 3.936527 4.069061
#> [10,] 3.955975 3.967665 4.288674
#> [11,] 4.110692 4.177246 4.178177
#> [12,] 4.109434 4.246707 4.419890
#> [13,] 4.208805 4.286228 4.226519
#> [14,] 3.996226 4.422754 3.948895
#> [15,] 4.333333 4.256287 4.758287
#> [16,] 4.115723 4.020359 4.609116
#> CAACCTCTCACCCTCA-b02 CAAGATCAGCCACCTG-b02 CAAGGCCAGCGATAGC-b02
#> [1,] 4.495798 4.263136 4.158676
#> [2,] 4.271709 4.142447 4.211187
#> [3,] 4.361345 4.180213 4.529680
#> [4,] 4.361345 4.243842 4.211187
#> [5,] 4.155462 4.986453 4.163242
#> [6,] 3.907563 4.109195 4.063927
#> [7,] 4.211485 5.080460 4.288813
#> [8,] 5.512605 4.385468 5.401826
#> [9,] 4.603641 4.202791 4.400685
#> [10,] 3.820728 4.185550 4.321918
#> [11,] 4.431373 4.152709 4.210046
#> [12,] 4.317927 4.114943 4.313927
#> [13,] 4.394958 4.382184 4.627854
#> [14,] 3.987395 4.394089 3.939498
#> [15,] 4.217087 4.055829 4.388128
#> [16,] 4.298319 4.172414 4.054795
#> CAAGGCCTCAGCCTAA-b02 CACACTCCAAAGCAAT-b02 CAGATCACATCGGGTC-b02
#> [1,] 4.197895 4.491166 4.162760
#> [2,] 4.076842 4.766784 4.188802
#> [3,] 4.189474 4.724382 4.173177
#> [4,] 4.004211 4.310954 4.157552
#> [5,] 4.840000 4.462898 4.221354
#> [6,] 4.028421 4.261484 4.244792
#> [7,] 5.395789 4.244994 4.375000
#> [8,] 4.167368 4.990577 5.098958
#> [9,] 4.216842 4.435807 4.360677
#> [10,] 4.048421 4.345112 4.102865
#> [11,] 4.200000 4.290931 4.209635
#> [12,] 4.172632 4.349823 4.326823
#> [13,] 4.148421 4.360424 4.496094
#> [14,] 4.411579 4.277974 4.031250
#> [15,] 4.085263 4.294464 4.207031
#> [16,] 3.873684 4.177856 4.023438
#> CAGCAGCGTAGAGCTG-b02 CAGCGACCACCAGGCT-b02 CAGCGACTCCCAACGG-b02
#> [1,] 4.646091 4.379233 4.426207
#> [2,] 4.197531 4.041761 4.395862
#> [3,] 4.134431 4.442438 4.332414
#> [4,] 4.186557 4.174944 4.022069
#> [5,] 4.390947 4.860045 4.503448
#> [6,] 4.408779 4.015801 3.634483
#> [7,] 4.176955 4.634312 4.423448
#> [8,] 5.327846 4.603837 5.544828
#> [9,] 4.654321 4.284424 4.448276
#> [10,] 4.235940 4.362302 3.685517
#> [11,] 4.006859 4.240406 4.321379
#> [12,] 4.511660 4.187359 4.161379
#> [13,] 4.584362 4.095937 4.518621
#> [14,] 4.170096 4.084650 4.117241
#> [15,] 4.130316 4.449210 4.055172
#> [16,] 4.139918 4.189616 4.262069
#> CAGCTAAGTCTTCGTC-b02 CAGGTGCAGAGCTGCA-b02 CATATTCAGAGCTGGT-b02
#> [1,] 4.216606 4.321712 4.214058
#> [2,] 4.795126 3.908875 3.923855
#> [3,] 4.683213 4.073693 4.097444
#> [4,] 4.305054 4.249604 4.210330
#> [5,] 4.424188 4.781300 5.066560
#> [6,] 4.351083 3.683043 3.776890
#> [7,] 4.504513 4.637876 5.057508
#> [8,] 4.820397 4.989699 4.469116
#> [9,] 4.270758 4.080032 4.099042
#> [10,] 4.187726 3.837559 4.030351
#> [11,] 4.594765 4.178288 4.356763
#> [12,] 4.862816 4.135499 3.954739
#> [13,] 4.330325 4.240095 4.302982
#> [14,] 4.101986 4.052298 4.361555
#> [15,] 4.309567 3.931062 4.210863
#> [16,] 4.096570 3.934231 4.095314
#> CATCGGGAGCACCGCT-b02 CATCGGGGTACCAGTT-b02 CATGACAGTCAAGCGA-b02
#> [1,] 4.446136 4.677098 4.336228
#> [2,] 4.250585 4.018492 4.099256
#> [3,] 4.197892 4.459459 4.008065
#> [4,] 4.236534 4.194879 4.373449
#> [5,] 4.593677 4.598862 4.946030
#> [6,] 3.954333 3.615932 4.018610
#> [7,] 4.235363 4.452347 4.830025
#> [8,] 5.291569 4.780939 4.509926
#> [9,] 4.642857 4.106686 4.142060
#> [10,] 4.377049 3.667141 3.995658
#> [11,] 4.188525 3.876245 4.149504
#> [12,] 4.395785 3.913229 4.056452
#> [13,] 4.385246 4.769559 4.267370
#> [14,] 3.894614 3.960171 4.198511
#> [15,] 4.237705 4.514936 3.904467
#> [16,] 4.146370 3.987198 4.076303
#> CATGGCGAGAACTGTA-b02 CCACTACCAGTCTTCC-b02 CCATTCGTCAAAGACA-b02
#> [1,] 4.471196 4.350634 4.547974
#> [2,] 3.853767 4.055363 4.383795
#> [3,] 4.264402 4.419839 4.020611
#> [4,] 4.172821 4.193772 3.976546
#> [5,] 4.782866 4.370242 4.845060
#> [6,] 4.044313 4.081892 3.906894
#> [7,] 4.335303 4.468281 4.436389
#> [8,] 4.726736 5.265283 5.108742
#> [9,] 4.299852 4.254902 4.306326
#> [10,] 3.960118 3.895040 3.972281
#> [11,] 4.103397 4.153403 4.090263
#> [12,] 4.169129 4.414072 4.108742
#> [13,] 4.635155 4.461361 4.560768
#> [14,] 4.477105 4.093426 4.482587
#> [15,] 3.901773 4.050750 3.949538
#> [16,] 4.043575 4.282584 4.078181
#> CCCATACCAGTGGAGT-b02 CCGGGATGTTCTGTTT-b02 CCGTACTCAGGTTTCA-b02
#> [1,] 4.644444 3.883480 4.338275
#> [2,] 3.866667 3.988827 4.192722
#> [3,] 3.908497 4.122905 4.083558
#> [4,] 4.269281 4.220271 4.336927
#> [5,] 4.718954 4.865124 4.493261
#> [6,] 4.000000 3.858739 3.943396
#> [7,] 4.409804 4.980048 4.350404
#> [8,] 4.745098 4.547486 5.212938
#> [9,] 4.322876 4.570630 4.512129
#> [10,] 3.882353 4.099761 3.956873
#> [11,] 4.212418 4.220271 4.450135
#> [12,] 4.184314 4.223464 4.296496
#> [13,] 4.588235 4.173184 4.881402
#> [14,] 3.876471 4.311253 4.416442
#> [15,] 3.925490 4.122905 4.225067
#> [16,] 3.964052 3.601756 4.470350
#> CCGTACTTCCAATGGT-b02 CCTATTAGTATCGCAT-b02 CGACCTTAGATGGCGT-b02
#> [1,] 4.530922 4.490509 4.409038
#> [2,] 3.648775 4.117882 4.271147
#> [3,] 4.012835 4.270729 4.247972
#> [4,] 4.432905 4.290709 4.316338
#> [5,] 4.933489 4.786214 3.993048
#> [6,] 3.673279 3.881119 3.857474
#> [7,] 4.971995 4.835165 4.215527
#> [8,] 4.506418 4.661339 4.730012
#> [9,] 4.288215 4.093906 5.137891
#> [10,] 3.897316 4.024975 4.531866
#> [11,] 4.087515 3.834166 4.095017
#> [12,] 3.907818 4.045954 4.077636
#> [13,] 4.172695 4.244755 4.354577
#> [14,] 4.414236 4.506494 4.084589
#> [15,] 4.035006 4.291708 4.348783
#> [16,] 4.196033 3.910090 3.944380
#> CGACCTTAGTACGTTC-b02 CGACCTTGTAGCTGCC-b02 CGACTTCGTGTGCGTC-b02
#> [1,] 4.588794 4.344666 4.209618
#> [2,] 4.272555 4.484174 4.376079
#> [3,] 4.653371 4.214537 4.036991
#> [4,] 4.185185 4.130129 4.363748
#> [5,] 4.291548 4.541618 4.258940
#> [6,] 4.119658 4.144197 3.653514
#> [7,] 4.413105 4.268464 3.879162
#> [8,] 5.046534 5.375147 4.937115
#> [9,] 4.686610 4.484174 5.509248
#> [10,] 4.574549 4.302462 5.034525
#> [11,] 4.286800 4.603751 3.843403
#> [12,] 4.266857 4.495897 4.051788
#> [13,] 4.207977 4.173505 4.007398
#> [14,] 4.448243 4.283705 4.104809
#> [15,] 4.215575 4.262603 4.982737
#> [16,] 4.498575 4.245018 4.007398
#> CGCCAAGCAGCCTGTG-b02 CGCGTTTGTTTGGGCC-b02 CGCTATCTCCCTCTTT-b02
#> [1,] 4.142462 4.215637 4.426407
#> [2,] 4.224066 4.385876 4.207792
#> [3,] 4.439834 4.373266 4.245671
#> [4,] 4.251729 4.279950 4.449134
#> [5,] 4.082988 4.050441 4.310606
#> [6,] 4.059474 3.993695 4.522727
#> [7,] 4.283541 3.988651 4.443723
#> [8,] 5.088520 5.152585 5.300866
#> [9,] 4.811895 4.456494 4.546537
#> [10,] 4.658368 4.168979 4.201299
#> [11,] 4.269710 4.122320 4.507576
#> [12,] 4.232365 4.513241 4.438312
#> [13,] 4.218534 4.451450 3.939394
#> [14,] 4.084371 4.061791 4.333333
#> [15,] 4.807746 4.361917 4.192641
#> [16,] 3.766252 4.418663 4.369048
#> CGCTGGAAGACGCTTT-b02 CGCTTCAAGGACCACA-b02 CGTAGCGGTTACGACT-b02
#> [1,] 4.249671 4.366213 4.258597
#> [2,] 4.268068 4.248299 4.332875
#> [3,] 4.583443 4.515873 4.337001
#> [4,] 4.157687 4.022676 4.481431
#> [5,] 4.399474 4.402494 4.089409
#> [6,] 4.324573 4.500000 3.939477
#> [7,] 4.394218 4.013605 4.294360
#> [8,] 5.097240 5.392290 5.740028
#> [9,] 4.576873 4.594104 4.132050
#> [10,] 4.017083 4.238095 4.145805
#> [11,] 4.321945 4.137188 4.401651
#> [12,] 4.504599 4.179138 4.363136
#> [13,] 4.549277 4.193878 4.368638
#> [14,] 4.191853 4.685941 3.924347
#> [15,] 4.261498 4.004535 4.548831
#> [16,] 4.424442 4.359410 4.371389
#> CGTCACTCAACGATCT-b02 CGTGTCTTCGAATGCT-b02 CTAACTTAGATCCCGC-b02
#> [1,] 4.277424 4.642276 4.164262
#> [2,] 4.082803 4.084785 4.312986
#> [3,] 4.076433 4.320557 4.300777
#> [4,] 4.347488 4.282230 4.170921
#> [5,] 4.972399 4.624855 4.968923
#> [6,] 3.864827 3.761905 4.033296
#> [7,] 4.899505 4.818815 4.572697
#> [8,] 4.927813 4.615563 5.067703
#> [9,] 4.016277 4.382114 4.296337
#> [10,] 4.070771 4.119628 4.233074
#> [11,] 4.172682 4.221835 4.368479
#> [12,] 4.058033 4.157956 4.110988
#> [13,] 4.190375 4.550523 4.289678
#> [14,] 4.343949 4.414634 4.422863
#> [15,] 4.164897 3.986063 4.227525
#> [16,] 3.903751 3.996516 4.104329
#> CTAAGACGTCCCGACA-b02 CTACATTAGAGGTTGC-b02 CTAGAGTAGTGAATTG-b02
#> [1,] 4.300872 4.457297 4.832016
#> [2,] 4.521802 4.390270 4.251976
#> [3,] 4.485465 4.428108 4.003953
#> [4,] 4.572674 4.352432 3.905138
#> [5,] 4.530523 4.335135 4.402174
#> [6,] 3.722384 3.785946 3.946640
#> [7,] 4.238372 4.191351 4.143281
#> [8,] 5.178779 5.040000 5.457510
#> [9,] 4.479651 4.390270 4.606719
#> [10,] 4.383721 3.874595 3.854743
#> [11,] 4.078488 4.265946 4.061265
#> [12,] 4.678779 4.122162 4.274704
#> [13,] 4.462209 3.910270 4.953557
#> [14,] 4.171512 4.650811 4.178854
#> [15,] 4.456395 4.135135 3.871542
#> [16,] 4.454942 4.006486 4.196640
#> CTAGAGTGTCGCGAAA-b02 CTAGCCTTCAACACAC-b02 CTAGCCTTCGCTAGCG-b02
#> [1,] 4.308717 4.440751 4.451058
#> [2,] 4.007773 4.390173 4.001323
#> [3,] 4.202110 4.484104 4.607143
#> [4,] 4.576346 4.351156 4.500000
#> [5,] 5.047751 4.184971 4.613757
#> [6,] 4.029983 3.849711 3.779101
#> [7,] 4.850639 3.940751 4.797619
#> [8,] 4.533037 5.482659 4.679894
#> [9,] 4.083287 4.650289 4.050265
#> [10,] 4.063298 3.908960 3.998677
#> [11,] 4.112160 4.401734 4.208995
#> [12,] 3.943365 4.492775 4.109788
#> [13,] 4.245974 4.774566 4.275132
#> [14,] 4.408107 4.118497 3.907407
#> [15,] 4.183232 4.070809 4.149471
#> [16,] 4.061077 4.306358 4.199735
#> CTCGAAAGTTTGGCGC-b02 CTCGGAGTCCACGCAG-b02 CTCGTCAAGCTGAAAT-b02
#> [1,] 4.615324 4.399160 4.417722
#> [2,] 4.258014 4.123249 4.139241
#> [3,] 4.216575 4.320728 4.084388
#> [4,] 4.608288 4.546218 4.115331
#> [5,] 4.080532 4.833333 4.963432
#> [6,] 3.954652 4.089636 4.088608
#> [7,] 4.410477 4.568627 4.744023
#> [8,] 4.904613 5.063025 4.483826
#> [9,] 4.496482 4.333333 4.263010
#> [10,] 4.039875 4.086835 3.834037
#> [11,] 4.240813 4.273109 4.198312
#> [12,] 4.201720 4.196078 4.059072
#> [13,] 4.311962 4.126050 4.163150
#> [14,] 4.469898 4.165266 4.147679
#> [15,] 4.350274 4.280112 4.350211
#> [16,] 4.271306 4.301120 3.834037
#> CTCGTCAGTGACGCCT-b02 CTCGTCATCATTTGGG-b02 CTGATAGGTAGCGCTC-b02
#> [1,] 4.542005 4.085513 4.279395
#> [2,] 4.138211 4.201207 3.953434
#> [3,] 4.275068 4.158954 4.185099
#> [4,] 4.302168 4.493461 4.233993
#> [5,] 4.128726 4.759557 4.675204
#> [6,] 4.100271 3.970825 3.919674
#> [7,] 3.968835 4.753521 4.756694
#> [8,] 5.023035 4.807344 4.424913
#> [9,] 4.760163 4.050302 4.200233
#> [10,] 4.089431 4.054829 3.894063
#> [11,] 3.976965 4.298793 4.095460
#> [12,] 4.168022 4.300302 4.185099
#> [13,] 4.574526 4.311368 4.413271
#> [14,] 4.420054 4.173541 4.474971
#> [15,] 4.173442 4.074447 4.284051
#> [16,] 4.695122 4.121730 4.287544
#> CTGCCTATCAGCTTAG-b02 CTGTTTAGTAAAGTCA-b02 CTTCTCTAGTACGTAA-b02
#> [1,] 4.417246 4.427343 4.242665
#> [2,] 4.460362 4.377472 3.827914
#> [3,] 4.458971 4.056750 4.056305
#> [4,] 4.710709 4.079966 4.268834
#> [5,] 4.218359 4.678418 5.279937
#> [6,] 4.297636 4.323302 3.844568
#> [7,] 4.304590 4.033534 5.199048
#> [8,] 4.961057 5.536543 4.578113
#> [9,] 4.424200 4.531384 4.007930
#> [10,] 4.248957 4.116079 3.827914
#> [11,] 4.489569 4.509888 3.967486
#> [12,] 4.458971 4.184007 3.926249
#> [13,] 4.043115 4.836629 4.114195
#> [14,] 4.354659 4.294067 4.269627
#> [15,] 4.695410 4.419604 4.128469
#> [16,] 4.470097 4.159931 3.805710
#> CTTCTCTCACTCGACG-b02 GAAACTCAGGAACTGC-b02 GAAATGACACAGACTT-b02
#> [1,] 4.437741 4.190042 3.858796
#> [2,] 4.464698 4.327489 4.579861
#> [3,] 4.061617 4.579243 4.292824
#> [4,] 4.336329 4.422160 4.103009
#> [5,] 4.482670 4.705470 4.053241
#> [6,] 4.644416 4.075035 3.626157
#> [7,] 3.962773 4.581346 4.284722
#> [8,] 5.568678 4.598878 4.957176
#> [9,] 4.550706 4.359046 4.973380
#> [10,] 4.234917 4.089060 4.335648
#> [11,] 4.569961 4.286115 3.892361
#> [12,] 4.169448 3.957924 4.109954
#> [13,] 4.069320 4.128331 4.101852
#> [14,] 4.331194 4.307153 4.379630
#> [15,] 4.514763 4.431276 5.113426
#> [16,] 4.472401 4.218794 4.359954
#> GAACATCGTCGACTAT-b02 GAACATCTCAAGATCC-b02 GAACCTAGTCACTGGC-b02
#> [1,] 4.169088 4.210075 4.191509
#> [2,] 4.295803 4.279743 4.286360
#> [3,] 4.298224 4.019293 4.353207
#> [4,] 4.596045 4.346195 4.327913
#> [5,] 4.828894 4.397642 4.941283
#> [6,] 3.852300 4.323687 4.111111
#> [7,] 4.787732 3.943194 4.915086
#> [8,] 4.721146 5.489818 4.666667
#> [9,] 4.339790 4.405145 4.205059
#> [10,] 4.016142 4.466238 4.132791
#> [11,] 4.527038 4.437299 4.338753
#> [12,] 4.409201 4.533762 4.233966
#> [13,] 4.143664 4.168274 4.308943
#> [14,] 4.370460 4.488746 4.096658
#> [15,] 3.986279 4.591640 4.009033
#> [16,] 4.171913 4.266881 4.208672
#> GACGCGTCAATCCAAC-b02 GACTGCGTCATCTGCC-b02 GAGTCCGTCAGCCTAA-b02
#> [1,] 4.523549 4.595430 4.264617
#> [2,] 4.193866 3.848118 4.297531
#> [3,] 4.134721 3.979839 4.273278
#> [4,] 4.283680 3.962366 4.246860
#> [5,] 4.446878 5.052419 4.928107
#> [6,] 4.228916 4.034946 4.331312
#> [7,] 4.032859 4.538978 4.860546
#> [8,] 5.164294 4.723118 4.484625
#> [9,] 4.984666 4.034946 4.325249
#> [10,] 4.154436 3.633065 4.213945
#> [11,] 4.315444 4.243280 4.182763
#> [12,] 4.366922 3.987903 4.147250
#> [13,] 4.935378 4.490591 4.306626
#> [14,] 4.348302 4.442204 4.507146
#> [15,] 3.866375 3.846774 4.118666
#> [16,] 4.518072 3.776882 4.229970
#> GATCGATTCTCCTATA-b02 GCACATACATGATCCA-b02 GCACTCTGTTTGTGTG-b02
#> [1,] 4.442204 4.609903 4.815927
#> [2,] 3.883065 4.245169 4.079634
#> [3,] 3.884409 4.464976 3.928198
#> [4,] 4.521505 4.536232 3.934726
#> [5,] 4.684140 4.599034 4.364230
#> [6,] 3.760753 3.977053 4.398172
#> [7,] 4.626344 4.355072 3.842037
#> [8,] 4.256720 5.071256 5.690601
#> [9,] 4.240591 4.364734 4.553525
#> [10,] 3.638441 4.305556 3.990862
#> [11,] 4.323925 4.394928 3.934726
#> [12,] 4.384409 4.392512 4.139687
#> [13,] 4.456989 4.578502 5.146214
#> [14,] 4.407258 3.937198 4.134465
#> [15,] 3.892473 4.088164 3.877285
#> [16,] 3.711022 4.455314 4.308094
#> GCATACATCCTCGCAT-b02 GCATGCGGTCGACTGC-b02 GCCAAATTCCAACCAA-b02
#> [1,] 4.45250 4.470466 4.335334
#> [2,] 4.21500 3.800000 4.580617
#> [3,] 4.31375 4.234197 4.325901
#> [4,] 4.57750 4.362694 4.121784
#> [5,] 4.50250 4.890155 4.352487
#> [6,] 3.81125 3.879793 4.205832
#> [7,] 4.59375 4.812435 4.286449
#> [8,] 4.92375 4.459067 5.235849
#> [9,] 4.38250 4.220725 4.465695
#> [10,] 4.19250 3.932642 4.370497
#> [11,] 4.23750 3.989637 4.602058
#> [12,] 4.04625 4.042487 4.437393
#> [13,] 4.01500 4.088083 4.426244
#> [14,] 4.07750 4.162694 4.433105
#> [15,] 4.16500 4.080829 4.336192
#> [16,] 4.13000 3.919171 4.314751
#> GCCTCTACAGCTTAAC-b02 GCGCGATGTTAAGGGC-b02 GCGCGATGTTTCGCTC-b02
#> [1,] 4.028796 4.179245 3.998592
#> [2,] 4.362565 4.403302 4.063380
#> [3,] 4.513089 4.400943 4.180282
#> [4,] 4.390052 4.274764 4.242254
#> [5,] 4.430628 4.817217 4.254930
#> [6,] 3.913613 4.050708 3.900000
#> [7,] 4.204188 4.229953 4.235211
#> [8,] 5.515707 4.876179 5.416901
#> [9,] 4.410995 4.943396 4.481690
#> [10,] 3.937173 4.153302 4.070423
#> [11,] 4.306283 4.346698 4.257746
#> [12,] 4.267016 4.430425 4.705634
#> [13,] 4.205497 4.617925 4.211268
#> [14,] 4.295812 3.976415 4.819718
#> [15,] 4.489529 3.880896 4.192958
#> [16,] 4.518325 4.204009 4.074648
#> GCTGCAGAGGGTTTCT-b02 GGACAAGGTAAGAGAG-b02 GGACAGACATGCTAGT-b02
#> [1,] 4.290978 4.426492 4.179605
#> [2,] 4.096569 4.136827 4.186184
#> [3,] 4.043202 4.457060 4.018421
#> [4,] 4.439644 4.420670 4.398026
#> [5,] 4.232529 4.563319 5.049342
#> [6,] 3.935197 4.103348 3.833553
#> [7,] 3.914867 3.937409 5.023026
#> [8,] 5.573062 5.310044 4.596711
#> [9,] 4.444727 4.438137 3.901316
#> [10,] 3.783990 4.346434 3.964474
#> [11,] 4.229987 4.109170 4.218421
#> [12,] 4.243964 4.248908 3.935526
#> [13,] 4.815756 4.551674 4.191447
#> [14,] 4.649301 4.283843 4.215132
#> [15,] 4.022872 4.339156 4.016447
#> [16,] 4.113088 4.119360 3.811184
#> GGGAGATGTACCATCA-b02 GGGTCTGTCCTCTAGC-b02 GGTGCGTCATTGGCGC-b02
#> [1,] 4.378788 4.197952 4.308762
#> [2,] 4.093939 3.932878 4.375522
#> [3,] 4.548485 4.136519 4.342142
#> [4,] 4.083838 4.246871 4.428373
#> [5,] 4.544444 5.332196 4.453408
#> [6,] 3.912121 4.122867 4.792768
#> [7,] 4.506061 4.934016 4.015299
#> [8,] 4.518182 4.333333 5.108484
#> [9,] 4.104040 4.222981 4.450626
#> [10,] 4.190909 4.151308 4.397775
#> [11,] 4.393939 4.007964 4.591099
#> [12,] 4.225253 4.353811 4.307371
#> [13,] 4.274747 4.382253 4.280946
#> [14,] 4.059596 4.111490 4.089013
#> [15,] 4.033333 4.027304 4.712100
#> [16,] 3.916162 4.316268 4.490960
#> GTAACTGAGCAGACTG-b02 GTACTCCAGATGGGTC-b02 GTACTCCTCATAGCAC-b02
#> [1,] 4.402330 4.353783 4.322660
#> [2,] 4.078821 4.356851 4.437603
#> [3,] 4.268677 4.426380 4.591133
#> [4,] 4.176833 4.570552 4.304598
#> [5,] 4.835504 4.126789 4.212644
#> [6,] 4.318711 3.932515 3.992611
#> [7,] 4.943797 4.155419 4.237274
#> [8,] 4.547635 5.494888 5.068144
#> [9,] 4.270048 4.306748 4.691297
#> [10,] 4.171350 4.118609 4.019704
#> [11,] 4.193968 4.392638 4.256979
#> [12,] 4.090473 4.339468 4.335796
#> [13,] 4.470870 4.296524 4.288998
#> [14,] 3.986292 4.110429 4.172414
#> [15,] 4.309801 4.176892 4.087028
#> [16,] 4.102125 4.115542 4.533662
#> GTATTCTTCTCGCATC-b02 GTCGGGTTCTTGTACT-b02 GTCTTCGGTCAAAGCG-b02
#> [1,] 4.500000 4.235474 4.362049
#> [2,] 4.235969 4.100917 4.264261
#> [3,] 4.309949 4.203874 4.899884
#> [4,] 4.338010 4.408767 4.195576
#> [5,] 4.010204 4.588175 4.628638
#> [6,] 4.331633 3.952090 4.330617
#> [7,] 4.355867 4.609582 4.237485
#> [8,] 5.044643 4.692151 5.038417
#> [9,] 4.415816 4.207951 4.526193
#> [10,] 4.367347 4.053007 4.310827
#> [11,] 4.424745 4.284404 4.621653
#> [12,] 4.514031 4.381244 4.352736
#> [13,] 3.918367 4.150866 4.291036
#> [14,] 4.012755 3.979613 4.414435
#> [15,] 4.521684 4.027523 4.633295
#> [16,] 4.386480 4.061162 4.473807
#> GTGAAGGCACCAGATT-b02 GTGCAGCCATGCCTTC-b02 GTGGGTCCAGTGGGAT-b02
#> [1,] 4.401490 4.044444 4.450588
#> [2,] 4.149007 4.602564 4.135294
#> [3,] 4.267384 4.203419 4.443529
#> [4,] 4.243377 4.255556 4.541176
#> [5,] 4.688742 4.619658 4.581176
#> [6,] 3.714404 3.517949 3.861176
#> [7,] 4.013245 4.296581 4.494118
#> [8,] 5.370033 5.081197 4.555294
#> [9,] 4.638245 3.818803 4.405882
#> [10,] 4.032285 3.821368 4.067059
#> [11,] 4.053808 4.497436 4.221176
#> [12,] 4.482616 4.096581 4.104706
#> [13,] 4.571192 4.091453 4.009412
#> [14,] 4.114238 4.755556 4.062353
#> [15,] 4.182947 4.076068 4.000000
#> [16,] 4.235099 3.986325 4.070588
#> GTTAAGCGTAAACGCG-b02 GTTCATTAGGGATGGG-b02 GTTCATTTCTTAGCCC-b02
#> [1,] 4.256012 4.128554 4.422794
#> [2,] 3.830101 4.025958 4.419118
#> [3,] 4.336695 4.207664 4.644608
#> [4,] 4.570209 4.488257 3.872549
#> [5,] 4.716059 4.045735 4.475490
#> [6,] 3.990690 4.620519 3.779412
#> [7,] 4.594259 4.082818 4.243873
#> [8,] 4.811482 5.122373 5.193627
#> [9,] 4.070597 4.426452 4.600490
#> [10,] 3.876649 4.163164 4.111520
#> [11,] 4.007758 4.082818 4.500000
#> [12,] 3.963538 4.388133 4.457108
#> [13,] 4.217998 4.330037 4.530637
#> [14,] 4.210240 4.870210 4.256127
#> [15,] 4.295578 4.088999 4.491422
#> [16,] 4.164469 4.755253 4.426471
#> GTTCTCGGTGGACGAT-b02 TACACGAAGGCATGGT-b02 TACCTATGTGTTGGGA-b02
#> [1,] 4.684697 4.295294 3.941989
#> [2,] 4.077836 4.277647 4.497238
#> [3,] 4.310026 4.037647 4.448895
#> [4,] 4.373351 4.418824 4.088398
#> [5,] 4.629288 4.945882 4.647790
#> [6,] 3.721636 3.928235 3.964088
#> [7,] 4.489446 4.875294 4.352210
#> [8,] 4.808707 4.741176 5.011050
#> [9,] 4.094987 4.052941 4.096685
#> [10,] 4.189974 3.931765 4.455801
#> [11,] 4.389182 4.076471 4.124309
#> [12,] 4.013193 3.869412 4.089779
#> [13,] 4.319261 4.314118 4.588398
#> [14,] 3.898417 4.289412 4.178177
#> [15,] 4.333773 4.415294 4.396409
#> [16,] 4.014512 4.387059 4.180939
#> TACGGTACAATCTACG-b02 TAGACCACAAGCGATG-b02 TAGGCATAGTACCGGA-b02
#> [1,] 4.626531 4.403896 4.212537
#> [2,] 3.856122 4.588312 3.931440
#> [3,] 4.173469 4.427273 4.678746
#> [4,] 4.556122 4.181818 4.564153
#> [5,] 4.865306 3.949351 4.485798
#> [6,] 3.643878 4.223377 3.985309
#> [7,] 4.640816 4.216883 4.281097
#> [8,] 4.696939 5.512987 4.910872
#> [9,] 4.161224 4.528571 4.536729
#> [10,] 3.889796 4.287013 4.195886
#> [11,] 4.131633 4.380519 4.560235
#> [12,] 3.867347 4.472727 4.572968
#> [13,] 4.481633 4.388312 4.321254
#> [14,] 4.005102 4.015584 4.213516
#> [15,] 4.564286 4.358442 4.231146
#> [16,] 4.072449 3.968831 4.258570
#> TATCAGGGTAAATGTG-b02 TATTACCCACCGATAT-b02 TCAATCTCAACACCTA-b02
#> [1,] 4.724679 4.216993 4.730562
#> [2,] 4.042796 4.316340 4.384911
#> [3,] 4.310984 4.411765 4.475751
#> [4,] 4.419401 4.230065 4.266359
#> [5,] 5.018545 4.499346 4.427252
#> [6,] 4.087019 4.101961 4.120092
#> [7,] 4.426534 4.184314 4.353349
#> [8,] 4.977175 5.196078 4.717475
#> [9,] 4.164051 4.801307 4.105466
#> [10,] 3.974322 3.924183 4.187837
#> [11,] 4.169757 4.125490 4.086220
#> [12,] 4.038516 4.197386 4.108545
#> [13,] 4.248217 4.854902 4.216320
#> [14,] 4.047076 4.149020 4.113164
#> [15,] 4.162625 4.373856 4.130870
#> [16,] 4.216833 4.342484 4.267898
#> TCAGATGGTTGCGTTA-b02 TCAGGTACACGGATAG-b02 TCCCGATTCAACGCTA-b02
#> [1,] 4.170807 4.251082 4.298069
#> [2,] 3.799172 4.073593 4.026029
#> [3,] 4.128364 4.262987 4.257767
#> [4,] 4.196687 4.451299 4.480269
#> [5,] 4.958592 4.705628 4.603694
#> [6,] 3.928571 4.064935 3.774139
#> [7,] 4.798137 5.016234 4.812762
#> [8,] 4.226708 4.827922 4.682620
#> [9,] 4.186335 4.333333 4.184719
#> [10,] 3.784679 4.094156 4.141898
#> [11,] 4.155280 4.170996 4.159530
#> [12,] 4.311594 4.050866 4.087322
#> [13,] 4.249482 4.205628 4.311503
#> [14,] 4.526915 4.477273 4.020991
#> [15,] 3.628364 4.113636 3.884971
#> [16,] 3.954451 4.173160 3.997481
#> TCTATTGGTACGCTGC-b02 TCTCATATCTTCATGT-b02 TCTGGAAGTGGAAAGA-b02
#> [1,] 4.438191 4.610855 4.262341
#> [2,] 4.377889 4.094688 4.296192
#> [3,] 4.254271 4.576212 4.215797
#> [4,] 4.109548 4.098152 3.837800
#> [5,] 4.754774 4.760970 4.359661
#> [6,] 3.933668 3.937644 4.452750
#> [7,] 4.670352 4.727483 3.789845
#> [8,] 4.692462 4.323326 5.438646
#> [9,] 4.294472 4.036952 4.909732
#> [10,] 4.267337 4.000000 3.980254
#> [11,] 4.105528 4.579677 3.953456
#> [12,] 4.097487 4.379908 4.152327
#> [13,] 4.266332 4.461894 4.520451
#> [14,] 4.383920 4.243649 4.565585
#> [15,] 3.938693 4.053118 3.995769
#> [16,] 4.213065 3.906467 4.655853
#> TGAAAGAAGCGTAATA-b02 TGACGGCTCCTACAGA-b02 TGAGAGGAGACTACAA-b02
#> [1,] 4.262056 4.333688 4.568928
#> [2,] 4.213831 4.070138 4.217724
#> [3,] 4.102821 3.978746 4.433260
#> [4,] 4.347589 4.461211 3.984683
#> [5,] 4.776160 4.963868 4.224289
#> [6,] 3.790719 4.000000 3.945295
#> [7,] 4.660601 4.755579 3.893873
#> [8,] 4.987261 4.874601 5.038293
#> [9,] 3.974522 4.432519 4.294311
#> [10,] 3.835305 3.996812 3.963895
#> [11,] 4.332120 4.083953 4.405908
#> [12,] 4.315742 4.042508 4.484683
#> [13,] 4.458599 4.414453 4.655361
#> [14,] 4.366697 4.201913 4.205689
#> [15,] 3.827116 3.907545 3.765864
#> [16,] 4.079163 3.869288 3.952954
#> TGAGAGGCAGCTGCAC-b02 TGAGGGATCGTACCGG-b02 TGCCCATGTACACCGC-b02
#> [1,] 4.409150 4.261084 4.253281
#> [2,] 4.169935 4.107389 4.176509
#> [3,] 4.441830 4.500493 4.475722
#> [4,] 4.462745 4.394089 4.337927
#> [5,] 4.154248 4.463054 4.975066
#> [6,] 3.593464 4.121182 4.057743
#> [7,] 4.244444 4.069951 4.969816
#> [8,] 5.177778 5.326108 4.503937
#> [9,] 4.158170 4.216749 4.134514
#> [10,] 4.304575 4.008867 4.083990
#> [11,] 4.355556 4.346798 4.432415
#> [12,] 4.566013 4.134975 4.048556
#> [13,] 4.411765 4.630542 4.486877
#> [14,] 3.967320 4.135961 4.322835
#> [15,] 4.539869 3.985222 4.307087
#> [16,] 4.257516 3.990148 4.112861
#> TGCCCATGTCCGTCAG-b02 TGCTGCTGTAATCACC-b02 TGGCCAGGTAAGTTCC-b02
#> [1,] 4.919473 3.886584 3.994475
#> [2,] 4.115666 4.514523 4.139963
#> [3,] 3.918009 4.396957 4.177716
#> [4,] 4.374817 4.341632 4.453039
#> [5,] 4.770864 3.822960 4.668508
#> [6,] 3.911420 3.986169 3.889503
#> [7,] 4.012445 4.051176 4.510129
#> [8,] 5.124451 4.864454 4.511050
#> [9,] 4.212299 5.152144 4.590239
#> [10,] 3.736457 5.037344 4.013812
#> [11,] 3.972914 4.318119 4.159300
#> [12,] 3.935578 4.190871 4.136280
#> [13,] 4.681552 4.392808 4.039595
#> [14,] 4.039531 4.735823 4.418969
#> [15,] 3.959736 4.937759 4.216390
#> [16,] 4.164714 4.334716 4.236648
#> TGGCGCATCAGCTGGC-b02 TGGTTCCAGGTACTCT-b02 TGTCCCAAGAGGTAGA-b02
#> [1,] 4.423306 4.246193 4.726954
#> [2,] 4.230678 4.145939 3.800467
#> [3,] 4.134364 4.392132 4.026838
#> [4,] 4.168847 4.299492 4.406068
#> [5,] 4.632580 4.346447 4.873979
#> [6,] 3.838288 4.567259 4.110852
#> [7,] 4.516052 4.102792 4.530922
#> [8,] 4.825208 5.465736 4.250875
#> [9,] 4.199762 4.552030 4.016336
#> [10,] 3.977408 4.397208 3.889148
#> [11,] 4.397146 4.766497 4.162194
#> [12,] 4.248514 4.755076 4.156359
#> [13,] 4.510107 4.305838 4.179697
#> [14,] 4.249703 4.196701 3.894982
#> [15,] 4.315101 4.631980 4.292882
#> [16,] 4.097503 4.383249 3.840140
#> TGTGTTTGTGCAGTAG-b02 TTAGGCAGTATATCCG-b02 TTGACTTTCTTATCTG-b02
#> [1,] 4.231481 4.431010 4.566968
#> [2,] 4.173611 4.237553 3.926048
#> [3,] 4.408565 4.349929 4.201315
#> [4,] 4.387731 4.510669 4.175842
#> [5,] 4.575231 4.782361 4.912901
#> [6,] 4.545139 4.268848 3.776500
#> [7,] 4.189815 4.796586 4.535744
#> [8,] 4.974537 4.617354 5.065735
#> [9,] 4.708333 4.099573 4.571898
#> [10,] 4.395833 4.213371 3.953164
#> [11,] 4.504630 4.199147 4.308135
#> [12,] 4.589120 4.066856 4.094495
#> [13,] 3.939815 4.334282 4.403451
#> [14,] 4.321759 4.177809 4.324569
#> [15,] 4.430556 4.536273 3.936730
#> [16,] 4.706019 4.002845 4.170090
#> TTGCCGTTCCTTTACA-b02 TTGTAGGAGGGATACC-b02 TTTATGCAGTGACTCT-b02
#> [1,] 4.609415 4.480787 4.353234
#> [2,] 4.297710 4.201500 4.369403
#> [3,] 4.315522 4.297095 4.569652
#> [4,] 4.189567 4.343018 4.312189
#> [5,] 4.726463 4.822868 4.651741
#> [6,] 4.236641 3.902530 3.922886
#> [7,] 4.082697 5.075914 4.281095
#> [8,] 5.105598 4.553889 5.460199
#> [9,] 4.362595 4.143393 4.613184
#> [10,] 4.430025 4.182755 4.252488
#> [11,] 4.165394 4.513590 4.240050
#> [12,] 4.381679 4.265230 4.722637
#> [13,] 4.447837 4.414246 4.243781
#> [14,] 4.008906 4.131209 4.216418
#> [15,] 4.536896 4.089972 4.115672
#> [16,] 4.440204 3.820056 4.262438
#> AGAGTGGCAGCTGCTG-500.1.1 CAACCAAGTCTCCCTA-500.1.1
#> [1,] 4.358209 4.598425
#> [2,] 3.934328 4.554331
#> [3,] 4.428358 4.450394
#> [4,] 3.795522 4.357480
#> [5,] 4.516418 4.510236
#> [6,] 4.047761 4.368504
#> [7,] 4.174627 4.456693
#> [8,] 4.723881 5.062992
#> [9,] 4.238806 4.529134
#> [10,] 4.508955 4.185827
#> [11,] 4.325373 4.138583
#> [12,] 4.185075 4.420472
#> [13,] 4.217910 4.703937
#> [14,] 4.229851 4.127559
#> [15,] 3.995522 4.181102
#> [16,] 4.352239 4.483465
#> TTTCCTCTCTCACATT-500.1.1 ACATCAGCAGTGGAGT-500.1.2
#> [1,] 4.159463 4.170732
#> [2,] 4.415797 5.434451
#> [3,] 4.321908 3.829268
#> [4,] 4.281669 4.460366
#> [5,] 3.986587 4.416159
#> [6,] 4.813711 5.074695
#> [7,] 3.921013 4.408537
#> [8,] 4.616990 4.711890
#> [9,] 4.663189 4.460366
#> [10,] 4.472429 4.734756
#> [11,] 4.418778 4.657012
#> [12,] 4.444113 4.513720
#> [13,] 4.478390 4.292683
#> [14,] 4.490313 4.501524
#> [15,] 4.453055 3.996951
#> [16,] 4.624441 4.507622
#> ACTGATGAGACAAGCC-500.1.2 AGTGAGGGTCGCCATG-500.1.2
#> [1,] 4.204931 4.314869
#> [2,] 4.485362 4.620991
#> [3,] 4.716487 4.256560
#> [4,] 4.009245 4.924198
#> [5,] 4.496148 4.862974
#> [6,] 4.152542 4.080175
#> [7,] 4.337442 4.622449
#> [8,] 5.026194 5.110787
#> [9,] 4.548536 4.966472
#> [10,] 4.702619 4.163265
#> [11,] 4.519260 4.327988
#> [12,] 4.365177 4.396501
#> [13,] 3.918336 4.638484
#> [14,] 4.400616 4.728863
#> [15,] 3.862866 4.040816
#> [16,] 4.417565 4.293003
#> CCTCTGATCGTACGGC-500.1.2 CGGAGCTTCTGTTTGT-500.1.2
#> [1,] 4.292929 4.712480
#> [2,] 4.297258 4.412322
#> [3,] 4.630592 4.464455
#> [4,] 4.147186 4.570300
#> [5,] 4.252525 4.827804
#> [6,] 4.024531 4.113744
#> [7,] 4.249639 3.976303
#> [8,] 5.064935 5.123223
#> [9,] 5.088023 4.884676
#> [10,] 4.359307 4.067930
#> [11,] 4.490620 4.036335
#> [12,] 4.672439 4.864139
#> [13,] 4.448773 4.652449
#> [14,] 4.584416 4.663507
#> [15,] 4.206349 4.409163
#> [16,] 4.753247 4.543444
#> TACTTGTCATACGCCG-500.1.2 TTGCCGTTCCTGTAGA-500.1.2
#> [1,] 4.761827 4.538235
#> [2,] 4.554649 4.238235
#> [3,] 4.543230 4.583824
#> [4,] 4.393148 4.092647
#> [5,] 4.686786 4.285294
#> [6,] 4.536705 4.379412
#> [7,] 4.019576 3.986765
#> [8,] 4.787928 4.566176
#> [9,] 5.003263 4.285294
#> [10,] 4.303426 4.207353
#> [11,] 4.344209 4.051471
#> [12,] 4.437194 4.332353
#> [13,] 4.595432 4.561765
#> [14,] 4.177814 4.030882
#> [15,] 4.207178 4.179412
#> [16,] 4.412724 4.742647
#> CTGTTTAAGAGCAATT-500.1.3 TCATTACTCGTGTAGT-500.1.3
#> [1,] 4.307238 4.498377
#> [2,] 4.457903 4.422078
#> [3,] 4.737075 4.259740
#> [4,] 4.457903 4.274351
#> [5,] 4.680945 4.280844
#> [6,] 4.296898 4.215909
#> [7,] 4.468242 3.939935
#> [8,] 4.432792 4.977273
#> [9,] 4.824225 4.899351
#> [10,] 4.310192 4.358766
#> [11,] 4.274742 4.626623
#> [12,] 4.700148 4.402597
#> [13,] 4.660266 4.733766
#> [14,] 4.391433 4.862013
#> [15,] 4.020679 4.214286
#> [16,] 4.054653 4.753247
#> AAAGTAGAGGACGAAA-500.2.1 AAAGTAGGTAAAGTCA-500.2.1
#> [1,] 4.145719 4.480737
#> [2,] 4.020036 4.309883
#> [3,] 4.362477 4.380235
#> [4,] 4.311475 4.376884
#> [5,] 3.956284 4.410385
#> [6,] 4.519126 4.415410
#> [7,] 3.808743 4.266332
#> [8,] 4.961749 4.747069
#> [9,] 4.612022 4.949749
#> [10,] 4.551913 4.184255
#> [11,] 3.919854 4.586265
#> [12,] 4.661202 4.160804
#> [13,] 4.537341 4.224456
#> [14,] 4.907104 4.599665
#> [15,] 4.489982 3.961474
#> [16,] 4.473588 4.487437
#> AAAGTAGGTCCTGCTT-500.2.1 AAATGCCGTATAAACG-500.2.1
#> [1,] 4.261290 4.135036
#> [2,] 4.490323 4.897810
#> [3,] 4.588710 4.040146
#> [4,] 4.469355 4.257299
#> [5,] 4.440323 4.456204
#> [6,] 4.438710 3.863139
#> [7,] 4.216129 4.330292
#> [8,] 4.838710 4.580292
#> [9,] 4.272581 4.925182
#> [10,] 4.314516 4.538321
#> [11,] 4.324194 4.253650
#> [12,] 4.598387 4.067518
#> [13,] 4.251613 4.447080
#> [14,] 4.240323 4.009124
#> [15,] 4.430645 5.065693
#> [16,] 4.917742 3.870438
#> AACCATGCATGCCCGA-500.2.1 AACCGCGAGGTGACCA-500.2.1
#> [1,] 4.1376 4.363803
#> [2,] 4.2928 4.223035
#> [3,] 3.9760 4.535649
#> [4,] 4.1952 4.372943
#> [5,] 4.1568 4.621572
#> [6,] 4.9504 4.521024
#> [7,] 3.9776 3.904936
#> [8,] 4.9040 5.199269
#> [9,] 4.7248 4.535649
#> [10,] 4.2944 4.546618
#> [11,] 3.8416 4.594150
#> [12,] 4.1792 4.493601
#> [13,] 3.9984 4.272395
#> [14,] 4.9152 4.383912
#> [15,] 4.0528 4.692870
#> [16,] 4.7376 4.755027
#> AACTGGTTCGAATGGG-500.2.1 AAGTCTGGTAGCACGA-500.2.1
#> [1,] 4.823437 4.721805
#> [2,] 4.609375 4.466165
#> [3,] 4.287500 4.359398
#> [4,] 4.612500 4.610526
#> [5,] 4.393750 4.181955
#> [6,] 4.509375 4.398496
#> [7,] 3.917187 4.088722
#> [8,] 4.726562 4.679699
#> [9,] 4.478125 4.712782
#> [10,] 4.910937 4.305263
#> [11,] 4.310937 4.279699
#> [12,] 4.692187 4.365414
#> [13,] 4.493750 4.406015
#> [14,] 4.381250 4.203008
#> [15,] 3.937500 4.291729
#> [16,] 4.440625 4.172932
#> AATCCAGTCGCCATAA-500.2.1 ACATCAGAGAATTGTG-500.2.1
#> [1,] 4.620438 4.626292
#> [2,] 3.916058 5.122600
#> [3,] 4.472628 4.220089
#> [4,] 4.735401 4.447563
#> [5,] 4.191606 4.292467
#> [6,] 4.266423 4.688331
#> [7,] 4.052920 3.989660
#> [8,] 5.186131 4.344165
#> [9,] 4.802920 4.206795
#> [10,] 4.060219 4.576071
#> [11,] 4.445255 4.429838
#> [12,] 4.687956 4.856721
#> [13,] 4.052920 4.646972
#> [14,] 4.403285 4.002954
#> [15,] 4.218978 3.849335
#> [16,] 4.587591 4.118168
#> ACCAGTAAGTCGAGTG-500.2.1 ACGCCGACACAGAGGT-500.2.1
#> [1,] 4.147193 3.972387
#> [2,] 4.418816 4.660750
#> [3,] 4.597876 4.913215
#> [4,] 4.582701 4.053254
#> [5,] 4.262519 5.175542
#> [6,] 4.430956 4.804734
#> [7,] 3.874052 4.325444
#> [8,] 4.640364 5.134122
#> [9,] 4.887709 4.165680
#> [10,] 4.329287 4.552268
#> [11,] 4.403642 4.844181
#> [12,] 4.215478 4.285996
#> [13,] 4.159332 4.595661
#> [14,] 4.332322 4.161736
#> [15,] 4.191199 3.925049
#> [16,] 4.393020 4.783037
#> ACGCCGAGTGTTGGGA-500.2.1 ACGGGCTCACGGTGTC-500.2.1
#> [1,] 4.762089 4.517941
#> [2,] 4.553191 4.324493
#> [3,] 4.290135 4.605304
#> [4,] 4.442940 4.330733
#> [5,] 5.088975 4.741030
#> [6,] 4.301741 4.390016
#> [7,] 4.083172 4.343214
#> [8,] 5.350097 5.198128
#> [9,] 4.806576 4.882995
#> [10,] 4.191489 4.254290
#> [11,] 4.228240 4.269891
#> [12,] 4.634429 4.439938
#> [13,] 4.537718 4.405616
#> [14,] 4.286267 4.421217
#> [15,] 4.030948 4.416537
#> [16,] 4.417795 3.987520
#> ACGGGTCGTCACAAGG-500.2.1 ACTGAACTCGCCATAA-500.2.1
#> [1,] 4.885145 4.328380
#> [2,] 3.958652 4.393759
#> [3,] 4.424196 4.679049
#> [4,] 4.312404 4.436850
#> [5,] 4.865237 4.438336
#> [6,] 4.889740 4.053492
#> [7,] 4.182236 4.421991
#> [8,] 5.064319 4.766716
#> [9,] 4.866769 5.078752
#> [10,] 4.644717 4.453195
#> [11,] 4.770291 4.365527
#> [12,] 4.332312 4.439822
#> [13,] 4.416539 4.580981
#> [14,] 4.663093 4.781575
#> [15,] 4.422665 4.239227
#> [16,] 4.486983 4.530461
#> ACTTACTCAATTGCTG-500.2.1 ACTTTCATCAAAGTAG-500.2.1
#> [1,] 4.618238 4.574850
#> [2,] 4.429675 4.564371
#> [3,] 4.214838 4.480539
#> [4,] 4.282844 4.423653
#> [5,] 4.630603 4.558383
#> [6,] 4.590417 4.080838
#> [7,] 4.102009 4.279940
#> [8,] 5.275116 5.215569
#> [9,] 4.616692 4.526946
#> [10,] 4.068006 4.065868
#> [11,] 4.340031 4.396707
#> [12,] 4.412674 4.766467
#> [13,] 4.505410 4.437126
#> [14,] 4.414219 4.202096
#> [15,] 4.224111 4.146707
#> [16,] 4.389490 3.985030
#> ACTTTCATCTAGCACA-500.2.1 AGAATAGAGCACAGGT-500.2.1
#> [1,] 4.793103 4.484211
#> [2,] 4.385307 3.948872
#> [3,] 4.412294 4.612030
#> [4,] 4.851574 4.019549
#> [5,] 4.788606 4.109774
#> [6,] 4.284858 4.130827
#> [7,] 4.529235 4.439098
#> [8,] 4.845577 4.753383
#> [9,] 4.436282 4.714286
#> [10,] 4.431784 3.995489
#> [11,] 4.329835 4.233083
#> [12,] 4.394303 4.461654
#> [13,] 4.529235 4.670677
#> [14,] 4.341829 4.275188
#> [15,] 4.419790 4.145865
#> [16,] 4.020990 4.673684
#> AGACGTTCAATAAGCA-500.2.1 AGACGTTTCAATCACG-500.2.1
#> [1,] 4.437186 4.621934
#> [2,] 4.222781 4.360750
#> [3,] 4.564489 4.634921
#> [4,] 4.288107 4.787879
#> [5,] 4.703518 4.304473
#> [6,] 4.343384 4.284271
#> [7,] 4.569514 4.295815
#> [8,] 4.564489 5.079365
#> [9,] 4.752094 4.906205
#> [10,] 4.251256 4.236652
#> [11,] 4.405360 4.681097
#> [12,] 4.512563 4.362193
#> [13,] 4.609715 4.129870
#> [14,] 4.180905 4.207792
#> [15,] 4.360134 4.513709
#> [16,] 4.420436 4.046176
#> AGAGTGGGTCGAAAGC-500.2.1 AGATTGCGTTACGGAG-500.2.1
#> [1,] 4.656627 4.858915
#> [2,] 4.421687 5.094574
#> [3,] 4.534639 4.623256
#> [4,] 4.620482 4.454264
#> [5,] 4.518072 3.913178
#> [6,] 4.305723 4.682171
#> [7,] 4.111446 4.117829
#> [8,] 4.932229 4.706977
#> [9,] 4.658133 4.111628
#> [10,] 4.067771 4.407752
#> [11,] 4.638554 4.269767
#> [12,] 4.177711 5.006202
#> [13,] 4.484940 4.551938
#> [14,] 4.219880 3.846512
#> [15,] 3.906627 3.840310
#> [16,] 4.138554 4.207752
#> AGCGGTCAGGTGTTAA-500.2.1 AGCTCCTAGCTAAACA-500.2.1
#> [1,] 4.712644 4.808743
#> [2,] 4.118774 4.482696
#> [3,] 4.413793 4.249545
#> [4,] 4.726054 4.604736
#> [5,] 4.427203 4.384335
#> [6,] 4.166667 4.469945
#> [7,] 4.091954 4.225865
#> [8,] 4.454023 5.216758
#> [9,] 4.360153 4.380692
#> [10,] 4.358238 4.444444
#> [11,] 4.295019 4.486339
#> [12,] 4.674330 4.234973
#> [13,] 3.996169 4.351548
#> [14,] 4.411877 3.908925
#> [15,] 4.358238 4.065574
#> [16,] 4.277778 4.493625
#> AGCTCCTCAAGTAGTA-500.2.1 AGCTCCTCACCAGTTA-500.2.1
#> [1,] 4.461394 4.383234
#> [2,] 4.397363 4.229541
#> [3,] 4.574388 4.255489
#> [4,] 4.097928 4.489022
#> [5,] 4.775895 4.606786
#> [6,] 4.011299 4.566866
#> [7,] 3.871940 4.181637
#> [8,] 4.538606 4.992016
#> [9,] 4.706215 4.622754
#> [10,] 4.440678 4.323353
#> [11,] 4.109228 4.774451
#> [12,] 4.363465 4.510978
#> [13,] 4.726930 4.650699
#> [14,] 4.316384 4.105788
#> [15,] 4.389831 4.447106
#> [16,] 4.346516 4.247505
#> AGGCCGTGTGAGTGAC-500.2.1 AGGTCCGAGCATCATC-500.2.1
#> [1,] 4.480992 4.429403
#> [2,] 4.423140 4.240175
#> [3,] 4.550413 4.627365
#> [4,] 4.239669 4.743814
#> [5,] 4.454545 4.765648
#> [6,] 4.396694 4.193595
#> [7,] 4.185124 4.451237
#> [8,] 5.122314 5.269287
#> [9,] 4.842975 4.593886
#> [10,] 4.061157 4.091703
#> [11,] 4.218182 4.439592
#> [12,] 4.152066 4.269287
#> [13,] 4.952066 4.304221
#> [14,] 4.195041 4.212518
#> [15,] 4.226446 4.094614
#> [16,] 4.528926 4.519651
#> AGTTGGTCAGATCCAT-500.2.1 ATCACGAAGAGCAATT-500.2.1
#> [1,] 4.248668 4.506686
#> [2,] 4.207815 4.279346
#> [3,] 4.493783 4.655275
#> [4,] 4.664298 4.463596
#> [5,] 4.419183 4.643388
#> [6,] 4.214920 4.315007
#> [7,] 3.827709 4.309064
#> [8,] 5.200710 4.787519
#> [9,] 4.253996 4.707281
#> [10,] 4.403197 4.344725
#> [11,] 4.582593 4.594354
#> [12,] 4.291297 4.679049
#> [13,] 4.426288 4.424963
#> [14,] 4.071048 4.396731
#> [15,] 4.584369 4.156018
#> [16,] 3.998224 4.340267
#> ATCGAGTGTTGTACAC-500.2.1 ATCTACTAGAAACCAT-500.2.1
#> [1,] 4.667254 4.444828
#> [2,] 4.992958 4.225862
#> [3,] 4.438380 4.051724
#> [4,] 4.068662 4.632759
#> [5,] 4.299296 4.179310
#> [6,] 4.496479 4.344828
#> [7,] 4.316901 4.437931
#> [8,] 4.556338 5.067241
#> [9,] 4.102113 4.563793
#> [10,] 4.066901 4.093103
#> [11,] 4.389085 4.693103
#> [12,] 4.670775 4.355172
#> [13,] 4.769366 4.268966
#> [14,] 4.214789 4.691379
#> [15,] 3.797535 4.453448
#> [16,] 4.117958 4.517241
#> ATCTGCCAGATGCGAC-500.2.1 ATGCGATGTTCGCGAC-500.2.1
#> [1,] 4.424731 4.634369
#> [2,] 4.467742 4.310786
#> [3,] 4.247312 4.447898
#> [4,] 4.544803 4.394881
#> [5,] 4.476703 4.190128
#> [6,] 4.132616 4.038391
#> [7,] 3.732975 4.049360
#> [8,] 5.118280 5.290676
#> [9,] 4.810036 4.789762
#> [10,] 4.102151 4.321755
#> [11,] 4.342294 4.425960
#> [12,] 4.537634 4.745887
#> [13,] 4.654122 5.274223
#> [14,] 4.265233 4.223035
#> [15,] 4.003584 4.627057
#> [16,] 4.623656 4.299817
#> ATGTGTGAGCACGCCT-500.2.1 ATTATCCAGGCCCGTT-500.2.1
#> [1,] 4.694704 4.819118
#> [2,] 5.308411 4.133824
#> [3,] 4.520249 4.132353
#> [4,] 4.507788 4.541176
#> [5,] 3.855140 4.489706
#> [6,] 5.046729 4.145588
#> [7,] 4.023364 3.976471
#> [8,] 4.348910 5.022059
#> [9,] 3.744548 4.589706
#> [10,] 4.744548 4.379412
#> [11,] 4.672897 4.135294
#> [12,] 5.406542 4.366176
#> [13,] 4.362928 4.808824
#> [14,] 4.283489 4.130882
#> [15,] 3.500000 4.191176
#> [16,] 4.176012 4.335294
#> CACACTCAGTCGTACT-500.2.1 CACAGTAAGCTCAACT-500.2.1
#> [1,] 4.657143 4.322807
#> [2,] 4.008403 4.531579
#> [3,] 4.221849 4.750877
#> [4,] 4.216807 4.685965
#> [5,] 4.260504 4.329825
#> [6,] 4.594958 4.147368
#> [7,] 4.080672 3.814035
#> [8,] 4.909244 4.703509
#> [9,] 4.598319 4.252632
#> [10,] 4.250420 4.196491
#> [11,] 4.278992 4.017544
#> [12,] 4.389916 4.514035
#> [13,] 4.616807 4.143860
#> [14,] 4.473950 4.166667
#> [15,] 4.100840 4.536842
#> [16,] 4.544538 4.050877
#> CACATAGAGGAACTGC-500.2.1 CAGAATCCAACTTGAC-500.2.1
#> [1,] 4.099812 4.620491
#> [2,] 4.035782 4.180375
#> [3,] 4.659134 4.623377
#> [4,] 4.310734 4.240981
#> [5,] 4.979284 4.536797
#> [6,] 4.666667 4.658009
#> [7,] 4.410546 3.712843
#> [8,] 5.203390 4.763348
#> [9,] 4.546139 4.917749
#> [10,] 4.610169 4.531025
#> [11,] 4.209040 4.443001
#> [12,] 4.655367 4.531025
#> [13,] 4.350282 4.177489
#> [14,] 4.150659 4.443001
#> [15,] 4.141243 4.356421
#> [16,] 4.638418 4.111111
#> CAGATCACACCAGATT-500.2.1 CAGCAGCAGTTACGGG-500.2.1
#> [1,] 4.204511 4.274725
#> [2,] 4.169925 4.256410
#> [3,] 4.657143 4.576923
#> [4,] 4.160902 3.956044
#> [5,] 4.410526 5.302198
#> [6,] 4.267669 4.652015
#> [7,] 4.237594 4.265568
#> [8,] 4.700752 5.031136
#> [9,] 4.449624 4.395604
#> [10,] 4.111278 4.234432
#> [11,] 4.305263 4.445055
#> [12,] 4.403008 4.421245
#> [13,] 4.242105 4.452381
#> [14,] 4.818045 4.461538
#> [15,] 4.111278 4.267399
#> [16,] 4.430075 4.853480
#> CAGCCGAGTCTCGTTC-500.2.1 CATATTCGTTCAGCGC-500.2.1
#> [1,] 4.651852 4.630814
#> [2,] 4.277037 4.356105
#> [3,] 4.481481 4.267442
#> [4,] 4.798519 4.203488
#> [5,] 4.268148 4.690407
#> [6,] 3.986667 4.456395
#> [7,] 4.423704 4.265988
#> [8,] 4.672593 4.809593
#> [9,] 4.968889 4.780523
#> [10,] 4.314074 4.084302
#> [11,] 4.195556 4.454942
#> [12,] 4.545185 4.148256
#> [13,] 4.469630 4.360465
#> [14,] 4.662222 4.079942
#> [15,] 4.102222 4.110465
#> [16,] 4.306667 4.418605
#> CATCAGATCGGCGGTT-500.2.1 CCACCTATCATGCTCC-500.2.1
#> [1,] 4.213967 4.788779
#> [2,] 4.344725 4.234323
#> [3,] 4.613670 4.764026
#> [4,] 4.273403 4.539604
#> [5,] 4.313522 4.384488
#> [6,] 4.413076 4.176568
#> [7,] 4.062407 4.432343
#> [8,] 5.065379 4.861386
#> [9,] 4.592868 4.863036
#> [10,] 4.147103 4.367987
#> [11,] 4.435364 4.056106
#> [12,] 4.610698 4.379538
#> [13,] 4.175334 4.815182
#> [14,] 4.496285 4.293729
#> [15,] 4.060921 4.135314
#> [16,] 4.433878 4.475248
#> CCCTCCTCAAGCTGGA-500.2.1 CCCTCCTGTTATGTGC-500.2.1
#> [1,] 4.441176 4.434470
#> [2,] 4.463235 4.576302
#> [3,] 4.483824 4.606822
#> [4,] 4.364706 4.621185
#> [5,] 4.169118 4.754039
#> [6,] 3.779412 4.649910
#> [7,] 4.210294 4.174147
#> [8,] 4.561765 5.107720
#> [9,] 5.433824 4.490126
#> [10,] 4.938235 4.263914
#> [11,] 3.948529 4.222621
#> [12,] 4.555882 4.601436
#> [13,] 4.200000 4.416517
#> [14,] 4.316176 4.725314
#> [15,] 4.941176 4.116697
#> [16,] 4.207353 4.324955
#> CCTAAAGGTTCAACCA-500.2.1 CCTACCAGTCTAAAGA-500.2.1
#> [1,] 3.957025 4.566890
#> [2,] 4.315702 4.127090
#> [3,] 4.634711 4.033445
#> [4,] 3.952066 4.005017
#> [5,] 4.452893 4.476589
#> [6,] 4.641322 4.580268
#> [7,] 4.039669 4.306020
#> [8,] 4.690909 4.832776
#> [9,] 4.614876 4.740803
#> [10,] 4.327273 4.183946
#> [11,] 4.282645 4.498328
#> [12,] 4.543802 4.496656
#> [13,] 4.181818 4.309365
#> [14,] 4.760331 4.770903
#> [15,] 4.095868 4.576923
#> [16,] 4.766942 4.546823
#> CCTTACGCAAGACGTG-500.2.1 CGATGTATCGCACTCT-500.2.1
#> [1,] 4.457101 4.408724
#> [2,] 4.353550 4.221325
#> [3,] 4.214497 4.345719
#> [4,] 4.471893 4.237480
#> [5,] 4.745562 4.332795
#> [6,] 4.392012 4.027464
#> [7,] 4.248521 4.200323
#> [8,] 5.142012 4.602585
#> [9,] 4.078402 4.552504
#> [10,] 4.331361 4.394184
#> [11,] 4.763314 4.327948
#> [12,] 4.276627 4.578352
#> [13,] 4.500000 4.749596
#> [14,] 4.335799 4.169628
#> [15,] 4.470414 4.319871
#> [16,] 4.551775 4.437803
#> CGCTATCCACGGCTAC-500.2.1 CGGACGTTCCAACCAA-500.2.1
#> [1,] 4.654676 4.128676
#> [2,] 4.426259 4.369485
#> [3,] 4.895683 4.762868
#> [4,] 4.348921 4.435662
#> [5,] 4.370504 4.209559
#> [6,] 4.260791 4.367647
#> [7,] 4.401079 4.577206
#> [8,] 4.928058 5.066176
#> [9,] 4.872302 4.463235
#> [10,] 4.361511 4.413603
#> [11,] 4.066547 4.167279
#> [12,] 4.649281 4.722426
#> [13,] 4.517986 4.727941
#> [14,] 4.212230 4.420956
#> [15,] 3.953237 4.123162
#> [16,] 4.428058 4.465074
#> CGGCTAGCAGCGAACA-500.2.1 CGTAGCGAGATCCCAT-500.2.1
#> [1,] 4.054688 4.729433
#> [2,] 4.869141 4.486289
#> [3,] 4.986328 4.725777
#> [4,] 4.152344 4.842779
#> [5,] 4.314453 4.881170
#> [6,] 4.289062 4.288848
#> [7,] 3.896484 4.244973
#> [8,] 4.841797 5.173675
#> [9,] 4.460938 4.669104
#> [10,] 4.130859 4.394881
#> [11,] 4.648438 4.449726
#> [12,] 4.279297 4.839122
#> [13,] 4.273438 4.255941
#> [14,] 4.560547 4.703839
#> [15,] 4.339844 4.477148
#> [16,] 4.115234 4.234004
#> CGTGAGCAGCGTCAAG-500.2.1 CGTTAGACACCAGCAC-500.2.1
#> [1,] 4.414784 4.424242
#> [2,] 4.455852 4.289773
#> [3,] 4.433265 4.590909
#> [4,] 4.102669 4.223485
#> [5,] 4.665298 4.323864
#> [6,] 4.786448 4.471591
#> [7,] 3.817248 4.333333
#> [8,] 5.112936 5.009470
#> [9,] 5.010267 4.717803
#> [10,] 4.242300 4.107955
#> [11,] 4.478439 4.030303
#> [12,] 4.737166 4.386364
#> [13,] 4.379877 4.323864
#> [14,] 4.158111 4.695076
#> [15,] 4.297741 4.471591
#> [16,] 4.410678 3.780303
#> CGTTAGAGTCTGATTG-500.2.1 CTAAGACGTTCGGGCT-500.2.1
#> [1,] 4.585736 3.982567
#> [2,] 4.377845 4.104596
#> [3,] 4.450683 4.220285
#> [4,] 4.396055 4.264659
#> [5,] 4.518968 4.922345
#> [6,] 4.235205 4.499208
#> [7,] 4.112291 4.231379
#> [8,] 4.819423 4.716323
#> [9,] 4.512898 4.524564
#> [10,] 4.261002 4.215531
#> [11,] 4.078907 4.213946
#> [12,] 4.420334 4.665610
#> [13,] 4.717754 4.275753
#> [14,] 4.461305 4.820919
#> [15,] 4.053111 3.954041
#> [16,] 4.500759 4.789223
#> CTACACCCATCCGTGG-500.2.1 CTACATTCACTTCTGC-500.2.1
#> [1,] 4.497660 4.792701
#> [2,] 4.349454 4.411679
#> [3,] 4.666147 4.741606
#> [4,] 4.379095 4.721168
#> [5,] 4.418097 4.480292
#> [6,] 4.408736 4.490511
#> [7,] 3.862715 4.452555
#> [8,] 4.981279 4.883212
#> [9,] 4.120125 4.369343
#> [10,] 4.336973 4.300730
#> [11,] 4.541342 4.547445
#> [12,] 4.599064 4.475912
#> [13,] 4.371295 4.360584
#> [14,] 4.179407 4.214599
#> [15,] 4.302652 4.404380
#> [16,] 4.081123 4.433577
#> CTAGCCTTCGCGATCG-500.2.1 CTCATTAGTCTAAACC-500.2.1
#> [1,] 5.051530 4.303030
#> [2,] 4.230274 4.253788
#> [3,] 4.198068 4.630682
#> [4,] 4.293076 4.210227
#> [5,] 4.500805 4.318182
#> [6,] 4.491143 4.251894
#> [7,] 3.743961 3.988636
#> [8,] 5.083736 4.700758
#> [9,] 4.181965 4.473485
#> [10,] 4.273752 4.297348
#> [11,] 4.078905 4.234848
#> [12,] 4.257649 4.384470
#> [13,] 4.763285 4.280303
#> [14,] 4.512077 4.142045
#> [15,] 3.951691 4.367424
#> [16,] 4.202899 4.234848
#> CTCATTATCCAATGGT-500.2.1 CTCGTCAGTGACGGTA-500.2.1
#> [1,] 4.285240 4.067227
#> [2,] 4.192371 4.307563
#> [3,] 4.461028 4.475630
#> [4,] 4.535655 4.754622
#> [5,] 4.344942 4.339496
#> [6,] 4.467662 4.144538
#> [7,] 4.466003 4.146218
#> [8,] 5.366501 4.798319
#> [9,] 4.538972 4.821849
#> [10,] 4.243781 4.586555
#> [11,] 4.273632 4.504202
#> [12,] 4.653400 4.467227
#> [13,] 4.273632 4.502521
#> [14,] 4.210614 4.628571
#> [15,] 3.873964 4.119328
#> [16,] 4.298507 4.425210
#> CTGCCTAGTCAACATC-500.2.1 CTGCTGTTCGTCTGCT-500.2.1
#> [1,] 4.425414 4.266145
#> [2,] 4.290976 4.003914
#> [3,] 4.574586 4.700587
#> [4,] 4.384899 4.598826
#> [5,] 4.788214 4.639922
#> [6,] 4.156538 4.440313
#> [7,] 4.136280 4.530333
#> [8,] 5.184162 4.444227
#> [9,] 4.324125 4.669276
#> [10,] 4.252302 4.467710
#> [11,] 4.338858 4.407045
#> [12,] 4.500921 4.616438
#> [13,] 4.368324 4.350294
#> [14,] 4.548803 4.272016
#> [15,] 4.604052 4.131115
#> [16,] 4.429098 4.242661
#> CTGGTCTAGACTACAA-500.2.1 CTGGTCTGTGCAGTAG-500.2.1
#> [1,] 4.287020 4.085072
#> [2,] 4.586837 4.524880
#> [3,] 4.489945 4.656501
#> [4,] 4.513711 4.508828
#> [5,] 4.778793 4.396469
#> [6,] 4.489945 4.269663
#> [7,] 3.976234 4.133226
#> [8,] 4.800731 5.101124
#> [9,] 5.153565 4.709470
#> [10,] 4.138940 4.412520
#> [11,] 4.155393 4.197432
#> [12,] 4.268739 4.505618
#> [13,] 4.308958 4.327448
#> [14,] 4.433272 4.725522
#> [15,] 3.946984 4.627608
#> [16,] 4.235832 4.107544
#> CTTGGCTAGGGTTCCC-500.2.1 CTTTGCGTCAGTTCGA-500.2.1
#> [1,] 4.236599 4.808550
#> [2,] 3.927911 4.671004
#> [3,] 4.081331 4.724907
#> [4,] 4.155268 4.159851
#> [5,] 4.090573 4.758364
#> [6,] 4.608133 4.721190
#> [7,] 3.720887 4.083643
#> [8,] 5.168207 5.070632
#> [9,] 4.902033 4.444238
#> [10,] 4.109057 3.918216
#> [11,] 3.940850 4.178439
#> [12,] 4.439926 4.189591
#> [13,] 4.275416 4.604089
#> [14,] 5.199630 4.120818
#> [15,] 3.883549 4.079926
#> [16,] 4.475046 4.587361
#> GACCAATTCAAGGTAA-500.2.1 GATCAGTAGTACGTTC-500.2.1
#> [1,] 4.330671 4.509542
#> [2,] 4.247604 4.131679
#> [3,] 4.404153 4.311069
#> [4,] 4.487220 4.017176
#> [5,] 4.675719 4.767176
#> [6,] 4.416933 4.093511
#> [7,] 4.528754 3.854962
#> [8,] 4.706070 4.988550
#> [9,] 4.829073 4.503817
#> [10,] 4.434505 4.001908
#> [11,] 4.458466 4.570611
#> [12,] 4.255591 4.515267
#> [13,] 4.394569 5.038168
#> [14,] 4.142173 3.946565
#> [15,] 4.284345 3.799618
#> [16,] 4.528754 4.362595
#> GATCAGTTCCTTTCGG-500.2.1 GATCGCGGTTAAGGGC-500.2.1
#> [1,] 4.226962 4.725490
#> [2,] 4.153584 4.598039
#> [3,] 4.653584 4.583333
#> [4,] 4.054608 4.736928
#> [5,] 4.897611 4.493464
#> [6,] 4.576792 4.212418
#> [7,] 4.418089 4.125817
#> [8,] 4.779863 4.421569
#> [9,] 4.617747 4.794118
#> [10,] 4.143345 4.369281
#> [11,] 4.962457 4.292484
#> [12,] 4.738908 4.558824
#> [13,] 4.305461 4.132353
#> [14,] 4.356655 4.480392
#> [15,] 3.991468 4.568627
#> [16,] 4.658703 4.196078
#> GATGAAACATTAGGCT-500.2.1 GCATGCGGTTCGGGCT-500.2.1
#> [1,] 4.279693 4.641337
#> [2,] 4.113027 4.416413
#> [3,] 4.722222 4.303951
#> [4,] 3.921456 4.448328
#> [5,] 4.337165 4.521277
#> [6,] 4.298851 4.334347
#> [7,] 3.908046 4.180851
#> [8,] 4.977011 5.062310
#> [9,] 4.704981 4.436170
#> [10,] 4.595785 3.996960
#> [11,] 4.423372 4.229483
#> [12,] 5.001916 3.995441
#> [13,] 4.534483 4.648936
#> [14,] 4.498084 4.503040
#> [15,] 4.149425 3.989362
#> [16,] 4.233716 4.208207
#> GCATGTATCATGTAGC-500.2.1 GCGCCAATCGGTTCGG-500.2.1
#> [1,] 4.416174 4.307087
#> [2,] 4.625247 4.671260
#> [3,] 4.641026 4.933071
#> [4,] 4.489152 4.429134
#> [5,] 4.447732 4.409449
#> [6,] 4.497041 4.360236
#> [7,] 4.197239 4.017717
#> [8,] 4.412229 4.631890
#> [9,] 4.648915 4.909449
#> [10,] 4.597633 4.527559
#> [11,] 4.143984 4.377953
#> [12,] 4.100592 4.354331
#> [13,] 4.558185 4.163386
#> [14,] 4.341223 4.358268
#> [15,] 4.289941 4.574803
#> [16,] 4.084813 4.064961
#> GCTCTGTGTAATTGGA-500.2.1 GGAAAGCCATCTGGTA-500.2.1
#> [1,] 4.911337 4.545120
#> [2,] 5.193314 4.033149
#> [3,] 4.607558 4.386740
#> [4,] 4.308140 4.132597
#> [5,] 4.287791 4.554328
#> [6,] 4.684593 4.209945
#> [7,] 4.231105 3.935543
#> [8,] 4.518895 4.651934
#> [9,] 4.107558 4.615101
#> [10,] 4.293605 3.972376
#> [11,] 4.518895 4.012891
#> [12,] 4.813953 4.745856
#> [13,] 4.582849 4.620626
#> [14,] 3.917151 3.937385
#> [15,] 3.888081 4.318600
#> [16,] 4.232558 4.414365
#> GGAACTTCACGGTAAG-500.2.1 GGAGCAATCTAGCACA-500.2.1
#> [1,] 4.579882 4.241715
#> [2,] 4.542899 4.471735
#> [3,] 4.372781 4.769981
#> [4,] 4.341716 4.259259
#> [5,] 4.378698 4.179337
#> [6,] 4.201183 4.153996
#> [7,] 4.036982 4.179337
#> [8,] 5.063609 4.918129
#> [9,] 4.643491 5.099415
#> [10,] 4.360947 4.370370
#> [11,] 4.189349 3.947368
#> [12,] 3.976331 4.362573
#> [13,] 4.548817 4.317739
#> [14,] 4.699704 4.348928
#> [15,] 4.226331 4.107212
#> [16,] 4.494083 4.280702
#> GGATGTTAGCGATAGC-500.2.1 GGGACCTAGCGCCTTG-500.2.1
#> [1,] 4.186386 4.298211
#> [2,] 4.416532 4.493042
#> [3,] 4.376013 4.598410
#> [4,] 4.698541 4.767396
#> [5,] 4.507293 4.262425
#> [6,] 4.387358 4.043738
#> [7,] 4.113452 3.842942
#> [8,] 4.936791 4.970179
#> [9,] 4.623987 4.741551
#> [10,] 4.372771 4.182903
#> [11,] 3.957861 4.268390
#> [12,] 4.721232 4.296223
#> [13,] 4.690438 4.465209
#> [14,] 4.815235 4.648111
#> [15,] 4.260940 4.232604
#> [16,] 4.452188 4.246521
#> GGGATGACACGGACAA-500.2.1 GGTGCGTCAAGCTGAG-500.2.1
#> [1,] 4.518142 4.352590
#> [2,] 4.134978 4.392430
#> [3,] 4.345428 4.298805
#> [4,] 4.193033 4.914343
#> [5,] 4.851959 4.653386
#> [6,] 4.811321 4.239044
#> [7,] 4.153846 4.426295
#> [8,] 4.693759 4.723108
#> [9,] 4.860668 4.561753
#> [10,] 4.494920 4.221116
#> [11,] 4.766328 4.613546
#> [12,] 4.493469 4.368526
#> [13,] 4.201742 4.215139
#> [14,] 4.641509 4.274900
#> [15,] 4.653120 4.334661
#> [16,] 4.352685 4.344622
#> GTAGGCCTCAACCAAC-500.2.1 GTCATTTGTTTGCATG-500.2.1
#> [1,] 4.597843 4.175701
#> [2,] 4.231125 4.315888
#> [3,] 4.711864 4.368224
#> [4,] 4.238829 4.284112
#> [5,] 4.679507 4.489720
#> [6,] 4.275809 4.211215
#> [7,] 3.995378 4.213084
#> [8,] 4.650231 4.766355
#> [9,] 5.067797 4.183178
#> [10,] 4.050847 4.353271
#> [11,] 4.684129 4.362617
#> [12,] 4.312789 4.312150
#> [13,] 4.298921 4.396262
#> [14,] 4.604006 4.231776
#> [15,] 4.120185 4.442991
#> [16,] 4.432974 4.097196
#> GTGAAGGCATGTAAGA-500.2.1 GTGCTTCTCCGAGCCA-500.2.1
#> [1,] 4.582278 4.776493
#> [2,] 4.273734 4.685934
#> [3,] 4.541139 4.023121
#> [4,] 4.365506 4.433526
#> [5,] 4.318038 4.314066
#> [6,] 3.737342 4.210019
#> [7,] 3.851266 4.194605
#> [8,] 4.829114 4.788054
#> [9,] 4.876582 4.710983
#> [10,] 4.430380 4.847784
#> [11,] 4.526899 4.211946
#> [12,] 4.333861 4.244701
#> [13,] 4.221519 4.275530
#> [14,] 4.405063 4.296724
#> [15,] 4.376582 3.789981
#> [16,] 4.278481 4.260116
#> TAAGAGACAAGAAAGG-500.2.1 TACACGAAGGCGCTCT-500.2.1
#> [1,] 4.303665 4.870438
#> [2,] 4.303665 4.644161
#> [3,] 4.682373 4.990876
#> [4,] 4.577661 4.578467
#> [5,] 4.343805 4.361314
#> [6,] 4.223386 3.976277
#> [7,] 4.394415 4.153285
#> [8,] 4.813264 4.914234
#> [9,] 5.115183 4.302920
#> [10,] 4.431065 4.184307
#> [11,] 4.029668 4.441606
#> [12,] 4.465969 4.775547
#> [13,] 4.415358 4.104015
#> [14,] 4.167539 4.127737
#> [15,] 4.040140 4.160584
#> [16,] 4.649215 3.700730
#> TACGGATGTTGCTCCT-500.2.1 TACGGGCCACAACGCC-500.2.1
#> [1,] 4.021442 4.655357
#> [2,] 4.366472 4.353571
#> [3,] 4.368421 4.705357
#> [4,] 4.426901 4.101786
#> [5,] 4.157895 4.619643
#> [6,] 4.395712 3.855357
#> [7,] 4.056530 4.150000
#> [8,] 4.752437 4.685714
#> [9,] 4.596491 4.475000
#> [10,] 4.614035 3.910714
#> [11,] 4.473684 4.301786
#> [12,] 4.159844 4.233929
#> [13,] 4.339181 4.169643
#> [14,] 4.245614 4.217857
#> [15,] 4.263158 4.317857
#> [16,] 4.417154 4.342857
#> TACTTACCATGGAATA-500.2.1 TAGACCAGTATCGCAT-500.2.1
#> [1,] 4.181260 4.200361
#> [2,] 4.199693 4.140794
#> [3,] 4.201229 4.597473
#> [4,] 4.317972 4.611913
#> [5,] 4.594470 4.323105
#> [6,] 4.066052 4.196751
#> [7,] 4.646697 4.010830
#> [8,] 5.095238 4.617329
#> [9,] 4.465438 4.398917
#> [10,] 3.947773 4.256318
#> [11,] 3.976959 4.138989
#> [12,] 4.219662 4.624549
#> [13,] 4.981567 4.537906
#> [14,] 3.955453 4.521661
#> [15,] 4.070661 4.386282
#> [16,] 4.814132 4.559567
#> TAGACCATCGCTGATA-500.2.1 TAGTTGGGTTATCCGA-500.2.1
#> [1,] 4.597403 4.149477
#> [2,] 4.532468 4.272048
#> [3,] 4.513709 4.644245
#> [4,] 4.194805 4.224215
#> [5,] 4.365079 4.186846
#> [6,] 4.215007 4.246637
#> [7,] 3.789322 3.940209
#> [8,] 4.989899 4.849028
#> [9,] 4.503608 5.107623
#> [10,] 3.894661 4.207773
#> [11,] 4.317460 4.022422
#> [12,] 4.316017 4.701046
#> [13,] 4.829726 4.442451
#> [14,] 4.370851 4.203288
#> [15,] 4.189033 3.889387
#> [16,] 4.360750 4.236173
#> TATGCCCCATTGGTAC-500.2.1 TCAACGAAGTTGCAGG-500.2.1
#> [1,] 4.776224 4.390060
#> [2,] 4.220280 4.626506
#> [3,] 4.384615 4.557229
#> [4,] 4.646853 4.489458
#> [5,] 4.597902 4.367470
#> [6,] 4.473776 4.611446
#> [7,] 4.480769 4.478916
#> [8,] 4.919580 5.161145
#> [9,] 4.192308 4.463855
#> [10,] 4.736014 4.189759
#> [11,] 4.541958 4.433735
#> [12,] 5.089161 4.757530
#> [13,] 3.959790 4.189759
#> [14,] 4.302448 4.209337
#> [15,] 4.389860 4.061747
#> [16,] 4.097902 3.987952
#> TCACGAAAGGCATTGG-500.2.1 TCAGATGTCCGAACGC-500.2.1
#> [1,] 4.475842 4.186691
#> [2,] 4.060029 4.064695
#> [3,] 4.399707 4.327172
#> [4,] 4.361640 3.905730
#> [5,] 4.595900 4.857671
#> [6,] 4.079063 4.672828
#> [7,] 4.269400 4.275416
#> [8,] 5.008785 5.060998
#> [9,] 4.386530 4.513863
#> [10,] 4.193265 4.107209
#> [11,] 4.421669 4.142329
#> [12,] 4.317716 4.523105
#> [13,] 4.449488 4.634011
#> [14,] 4.346999 4.138632
#> [15,] 4.383602 4.249538
#> [16,] 4.235725 4.898336
#> TCAGCTCGTTCGTTGA-500.2.1 TCAGGATTCAGGTTCA-500.2.1
#> [1,] 4.614243 4.558209
#> [2,] 4.204748 4.601493
#> [3,] 4.323442 4.582090
#> [4,] 4.188427 4.574627
#> [5,] 4.543027 4.462687
#> [6,] 4.724036 4.252239
#> [7,] 4.227003 4.471642
#> [8,] 5.234421 5.182090
#> [9,] 4.666172 4.507463
#> [10,] 4.451039 3.989552
#> [11,] 4.471810 4.267164
#> [12,] 4.562315 4.744776
#> [13,] 4.532641 4.501493
#> [14,] 5.008902 4.456716
#> [15,] 4.307122 4.323881
#> [16,] 4.280415 4.050746
#> TCATTACTCACAGTAC-500.2.1 TCGAGGCAGGGATCTG-500.2.1
#> [1,] 4.171053 4.521021
#> [2,] 4.485197 4.199700
#> [3,] 4.605263 4.372372
#> [4,] 4.417763 4.243243
#> [5,] 4.215461 4.171171
#> [6,] 4.514803 4.406907
#> [7,] 4.182566 4.148649
#> [8,] 5.082237 4.926426
#> [9,] 4.583882 4.591592
#> [10,] 4.019737 4.325826
#> [11,] 4.417763 4.540541
#> [12,] 4.511513 4.554054
#> [13,] 4.332237 4.075075
#> [14,] 4.434211 4.656156
#> [15,] 4.077303 4.339339
#> [16,] 4.603618 4.447447
#> TCGCGTTCATCGGAAG-500.2.1 TCGCGTTGTGGGTATG-500.2.1
#> [1,] 5.069853 4.420183
#> [2,] 4.411765 4.251376
#> [3,] 4.681985 4.772477
#> [4,] 4.487132 4.025688
#> [5,] 4.174632 4.566972
#> [6,] 4.284926 4.060550
#> [7,] 4.018382 4.198165
#> [8,] 4.729779 4.699083
#> [9,] 4.821691 4.845872
#> [10,] 4.167279 4.651376
#> [11,] 4.286765 4.212844
#> [12,] 4.549632 4.537615
#> [13,] 4.698529 4.719266
#> [14,] 4.525735 4.330275
#> [15,] 4.007353 4.014679
#> [16,] 4.253676 4.113761
#> TCGTAGAAGGTTCCTA-500.2.1 TCTCTAAAGAGCAATT-500.2.1
#> [1,] 4.281469 4.776294
#> [2,] 4.005245 4.574290
#> [3,] 4.496503 4.569282
#> [4,] 4.256993 4.308848
#> [5,] 4.966783 4.711185
#> [6,] 4.793706 4.412354
#> [7,] 4.162587 4.230384
#> [8,] 4.823427 5.063439
#> [9,] 4.692308 4.372287
#> [10,] 4.498252 4.205342
#> [11,] 4.963287 4.452421
#> [12,] 4.293706 4.469115
#> [13,] 3.895105 4.255426
#> [14,] 4.800699 4.388982
#> [15,] 4.356643 4.305509
#> [16,] 4.877622 4.150250
#> TGAGCCGGTAGCTCCG-500.2.1 TGCCAAAAGCTAGTGG-500.2.1
#> [1,] 4.232143 4.750000
#> [2,] 5.047619 4.515896
#> [3,] 4.494048 4.115607
#> [4,] 4.273810 4.367052
#> [5,] 4.184524 4.283237
#> [6,] 4.013889 4.573699
#> [7,] 4.353175 4.114162
#> [8,] 4.753968 4.900289
#> [9,] 4.795635 4.429191
#> [10,] 4.150794 4.517341
#> [11,] 4.293651 3.919075
#> [12,] 4.365079 4.335260
#> [13,] 4.246032 4.771676
#> [14,] 4.043651 4.436416
#> [15,] 4.392857 3.930636
#> [16,] 4.365079 4.397399
#> TGCCCTAAGGCTACGA-500.2.1 TGCCCTAGTATGAATG-500.2.1
#> [1,] 4.497345 4.385455
#> [2,] 4.493805 4.209091
#> [3,] 4.311504 4.558182
#> [4,] 4.465487 4.510909
#> [5,] 4.327434 4.363636
#> [6,] 4.573451 4.118182
#> [7,] 4.152212 4.105455
#> [8,] 4.757522 4.903636
#> [9,] 4.909735 4.316364
#> [10,] 4.219469 4.390909
#> [11,] 4.113274 4.369091
#> [12,] 4.205310 4.367273
#> [13,] 4.444248 4.070909
#> [14,] 5.042478 4.232727
#> [15,] 4.182301 4.327273
#> [16,] 4.251327 4.307273
#> TGCGGGTGTGATGTGG-500.2.1 TGCTACCTCTACCAGA-500.2.1
#> [1,] 4.226734 4.439324
#> [2,] 4.472081 4.242704
#> [3,] 4.307953 4.380952
#> [4,] 4.475465 4.164363
#> [5,] 5.111675 4.940092
#> [6,] 4.426396 4.167435
#> [7,] 4.350254 4.003072
#> [8,] 4.842640 5.161290
#> [9,] 4.609137 4.652842
#> [10,] 4.549915 4.064516
#> [11,] 4.265651 4.414747
#> [12,] 4.502538 4.393241
#> [13,] 4.174281 4.494624
#> [14,] 4.472081 4.336406
#> [15,] 4.162437 4.150538
#> [16,] 4.693739 4.156682
#> TGGGAAGAGAAGAAGC-500.2.1 TTAGTTCGTCTGCGGT-500.2.1
#> [1,] 4.414484 4.122449
#> [2,] 4.234206 4.248609
#> [3,] 4.697997 4.411874
#> [4,] 4.274268 4.487941
#> [5,] 3.924499 4.371058
#> [6,] 3.952234 4.354360
#> [7,] 4.359014 4.085343
#> [8,] 4.659476 4.480519
#> [9,] 5.013867 4.864564
#> [10,] 4.568567 4.692022
#> [11,] 4.283513 4.513915
#> [12,] 4.397535 4.105751
#> [13,] 4.306626 4.502783
#> [14,] 4.614792 4.122449
#> [15,] 4.644068 4.256030
#> [16,] 4.172573 4.237477
#> TTCTACAAGTGACATA-500.2.1 TTCTACATCGCCATAA-500.2.1
#> [1,] 4.382298 4.054386
#> [2,] 4.259887 4.221053
#> [3,] 4.483992 4.521053
#> [4,] 4.540490 3.973684
#> [5,] 4.435028 4.335088
#> [6,] 4.510358 3.931579
#> [7,] 4.145009 3.991228
#> [8,] 5.423729 5.043860
#> [9,] 4.548023 5.338596
#> [10,] 3.474576 5.085965
#> [11,] 4.657250 3.857895
#> [12,] 4.619586 4.217544
#> [13,] 4.512241 4.673684
#> [14,] 4.566855 4.542105
#> [15,] 4.254237 4.542105
#> [16,] 4.175141 4.338596
#> TTCTCCTAGCTGATAA-500.2.1 TTGAACGTCTGATTCT-500.2.1
#> [1,] 4.187590 4.724786
#> [2,] 4.304473 3.926496
#> [3,] 4.471861 4.299145
#> [4,] 4.415584 4.152137
#> [5,] 4.308802 4.673504
#> [6,] 4.417027 4.141880
#> [7,] 4.031746 4.160684
#> [8,] 4.477633 4.986325
#> [9,] 4.707071 4.767521
#> [10,] 4.239538 3.728205
#> [11,] 4.173160 3.941880
#> [12,] 4.483405 3.982906
#> [13,] 4.669553 4.888889
#> [14,] 4.063492 4.225641
#> [15,] 4.473304 3.834188
#> [16,] 4.396825 4.085470
#> TTGCCGTTCGGCGCTA-500.2.1 TTGGCAATCACGCATA-500.2.1
#> [1,] 4.071429 4.480712
#> [2,] 4.277778 4.311573
#> [3,] 4.555556 4.485163
#> [4,] 4.396825 4.418398
#> [5,] 4.023810 4.459941
#> [6,] 4.835317 4.224036
#> [7,] 4.099206 4.103858
#> [8,] 4.494048 5.010386
#> [9,] 4.321429 4.421365
#> [10,] 4.095238 4.307122
#> [11,] 4.170635 4.544510
#> [12,] 4.103175 4.216617
#> [13,] 3.922619 4.811573
#> [14,] 4.275794 4.347181
#> [15,] 4.037698 4.117211
#> [16,] 4.646825 4.124629
#> TTTCCTCTCACAGGCC-500.2.1 TTTGTCACAAAGGTGC-500.2.1
#> [1,] 4.547431 4.454392
#> [2,] 3.786561 4.766892
#> [3,] 4.229249 4.334459
#> [4,] 4.217391 4.326014
#> [5,] 4.217391 4.422297
#> [6,] 4.804348 4.236486
#> [7,] 4.181818 3.935811
#> [8,] 4.871542 4.251689
#> [9,] 4.673913 4.369932
#> [10,] 4.005929 4.577703
#> [11,] 4.122530 4.293919
#> [12,] 4.330040 4.412162
#> [13,] 4.262846 4.925676
#> [14,] 4.636364 4.103041
#> [15,] 4.290514 4.094595
#> [16,] 4.853755 4.312500
#> AACCATGTCTGCGTAA-500.2.2 AACCGCGCATCATCCC-500.2.2
#> [1,] 4.073005 4.762684
#> [2,] 3.969440 5.009820
#> [3,] 4.628183 4.461538
#> [4,] 3.943973 4.548282
#> [5,] 4.475382 4.232406
#> [6,] 4.106961 4.659574
#> [7,] 4.354839 4.209493
#> [8,] 4.872666 4.581015
#> [9,] 4.578947 4.072013
#> [10,] 4.286927 4.489362
#> [11,] 4.427844 4.569558
#> [12,] 3.994907 4.504092
#> [13,] 4.607810 4.256956
#> [14,] 4.300509 3.847791
#> [15,] 4.524618 3.905074
#> [16,] 4.161290 3.959083
#> ACACCAAAGCTAAGAT-500.2.2 ACACTGAAGTCATCCA-500.2.2
#> [1,] 4.150579 4.588138
#> [2,] 4.000000 4.871499
#> [3,] 3.862934 4.042834
#> [4,] 3.945946 4.224053
#> [5,] 4.011583 4.219110
#> [6,] 4.720077 4.601318
#> [7,] 4.001931 4.286656
#> [8,] 4.745174 4.797364
#> [9,] 4.577220 3.894563
#> [10,] 4.415058 4.593081
#> [11,] 3.963320 4.225700
#> [12,] 4.505792 4.362438
#> [13,] 4.285714 4.581549
#> [14,] 4.791506 4.365733
#> [15,] 4.341699 4.084020
#> [16,] 4.511583 3.955519
#> ACGAGGAGTGGTACAG-500.2.2 ACGCCAGAGGGTCTCC-500.2.2
#> [1,] 4.741533 4.243284
#> [2,] 4.399287 4.440299
#> [3,] 4.748663 4.507463
#> [4,] 4.320856 4.213433
#> [5,] 4.540107 4.500000
#> [6,] 4.139037 4.277612
#> [7,] 4.588235 4.043284
#> [8,] 4.454545 4.998507
#> [9,] 4.852050 4.614925
#> [10,] 3.980392 4.252239
#> [11,] 4.420677 4.414925
#> [12,] 4.688057 4.247761
#> [13,] 4.493761 4.683582
#> [14,] 4.133690 4.117910
#> [15,] 4.032086 4.289552
#> [16,] 4.652406 4.741791
#> ACGCCGACACTGTGTA-500.2.2 ACGGCCACATCGGGTC-500.2.2
#> [1,] 4.367113 4.001678
#> [2,] 4.441683 4.050336
#> [3,] 4.739962 4.672819
#> [4,] 4.604207 4.338926
#> [5,] 4.567878 4.651007
#> [6,] 4.173996 4.315436
#> [7,] 3.942639 4.397651
#> [8,] 4.772467 5.281879
#> [9,] 4.481836 4.379195
#> [10,] 3.965583 4.335570
#> [11,] 4.604207 4.077181
#> [12,] 4.168260 4.011745
#> [13,] 4.413002 4.484899
#> [14,] 4.302103 4.046980
#> [15,] 4.059273 3.959732
#> [16,] 4.028681 4.741611
#> ACGGCCATCCAGGGCT-500.2.2 ACGGGCTAGCTAGTCT-500.2.2
#> [1,] 4.595197 4.130638
#> [2,] 4.339623 4.648523
#> [3,] 4.454545 4.545879
#> [4,] 3.977702 4.306376
#> [5,] 3.970840 4.376361
#> [6,] 4.523156 4.152411
#> [7,] 3.885077 4.297045
#> [8,] 4.677530 4.461897
#> [9,] 4.806175 4.674961
#> [10,] 4.096055 4.519440
#> [11,] 4.500858 4.334370
#> [12,] 4.586621 4.556765
#> [13,] 4.504288 4.321928
#> [14,] 4.353345 4.222395
#> [15,] 4.169811 4.914463
#> [16,] 4.603774 4.527216
#> ACTATCTGTAAGGATT-500.2.2 ACTTTCAAGTACGACG-500.2.2
#> [1,] 4.818966 4.387692
#> [2,] 4.534483 4.170769
#> [3,] 4.770690 4.049231
#> [4,] 4.500000 4.095385
#> [5,] 4.379310 4.633846
#> [6,] 4.172414 4.716923
#> [7,] 4.027586 3.880000
#> [8,] 4.818966 4.618462
#> [9,] 4.558621 4.544615
#> [10,] 4.350000 4.284615
#> [11,] 4.167241 4.398462
#> [12,] 4.777586 4.287692
#> [13,] 4.351724 4.664615
#> [14,] 4.520690 4.300000
#> [15,] 4.018966 4.178462
#> [16,] 4.456897 4.635385
#> AGAGTGGCAAACGTGG-500.2.2 AGAGTGGGTCAGTGGA-500.2.2
#> [1,] 4.216374 4.583333
#> [2,] 4.359649 3.801282
#> [3,] 4.646199 4.262821
#> [4,] 4.508772 4.291667
#> [5,] 4.309942 4.455128
#> [6,] 3.887427 4.072115
#> [7,] 4.169591 4.599359
#> [8,] 4.793860 4.746795
#> [9,] 4.767544 4.580128
#> [10,] 4.581871 4.155449
#> [11,] 4.207602 4.408654
#> [12,] 4.128655 4.758013
#> [13,] 4.217836 4.402244
#> [14,] 4.527778 4.450321
#> [15,] 4.134503 4.166667
#> [16,] 4.510234 4.671474
#> AGATTGCCATGCCTAA-500.2.2 AGATTGCTCCACGACG-500.2.2
#> [1,] 4.625786 5.828054
#> [2,] 4.457547 3.607843
#> [3,] 4.286164 4.000000
#> [4,] 4.539308 3.832579
#> [5,] 4.477987 5.850679
#> [6,] 4.544025 5.987934
#> [7,] 4.025157 3.704374
#> [8,] 5.004717 3.901961
#> [9,] 4.617925 5.117647
#> [10,] 4.261006 3.625943
#> [11,] 3.913522 3.413273
#> [12,] 4.816038 3.705882
#> [13,] 4.399371 3.671192
#> [14,] 4.584906 3.871795
#> [15,] 3.946541 3.873303
#> [16,] 4.279874 5.076923
#> AGCAGCCGTAAGTGTA-500.2.2 AGCTTGATCTCGATGA-500.2.2
#> [1,] 4.531394 4.538020
#> [2,] 4.473201 4.229555
#> [3,] 4.451761 4.540890
#> [4,] 4.398162 4.497848
#> [5,] 4.246554 4.572453
#> [6,] 3.992343 4.375897
#> [7,] 4.323124 4.212339
#> [8,] 4.519142 4.843615
#> [9,] 4.660031 4.487805
#> [10,] 4.381317 4.255380
#> [11,] 4.464012 3.852224
#> [12,] 4.698315 4.824964
#> [13,] 4.182236 4.407461
#> [14,] 4.343032 4.317073
#> [15,] 4.519142 3.902439
#> [16,] 4.049005 4.410330
#> AGGGATGTCATTTGGG-500.2.2 AGGTCCGTCTAACCGA-500.2.2
#> [1,] 4.826162 4.285451
#> [2,] 4.375215 4.412523
#> [3,] 4.628227 4.618785
#> [4,] 4.208262 4.252302
#> [5,] 4.869191 4.469613
#> [6,] 4.204819 4.627993
#> [7,] 4.208262 4.184162
#> [8,] 4.662651 4.898711
#> [9,] 5.072289 4.581952
#> [10,] 3.991394 4.666667
#> [11,] 4.012048 4.138122
#> [12,] 4.290878 4.867403
#> [13,] 4.728055 4.821363
#> [14,] 3.972461 4.381215
#> [15,] 4.161790 4.414365
#> [16,] 4.419966 4.215470
#> AGTTGGTAGGCGATAC-500.2.2 ATCATCTAGTGCGATG-500.2.2
#> [1,] 4.672727 4.590734
#> [2,] 4.216364 4.534749
#> [3,] 4.580000 4.555985
#> [4,] 4.394545 4.640927
#> [5,] 4.238182 4.857143
#> [6,] 4.321818 4.805019
#> [7,] 4.200000 4.602317
#> [8,] 4.750909 4.945946
#> [9,] 5.052727 4.567568
#> [10,] 4.607273 4.312741
#> [11,] 4.209091 4.368726
#> [12,] 4.749091 5.067568
#> [13,] 4.321818 4.222008
#> [14,] 4.581818 4.872587
#> [15,] 4.194545 4.104247
#> [16,] 4.565455 4.584942
#> ATCTACTAGAAACGAG-500.2.2 CAAGGCCCATAAAGGT-500.2.2
#> [1,] 4.447898 4.246554
#> [2,] 4.669104 4.359877
#> [3,] 4.104205 4.465544
#> [4,] 4.407678 4.245023
#> [5,] 4.091408 4.555896
#> [6,] 3.762340 3.900459
#> [7,] 4.287020 4.456355
#> [8,] 4.647166 5.165391
#> [9,] 5.197441 4.534456
#> [10,] 4.400366 4.018377
#> [11,] 4.451554 3.987749
#> [12,] 4.098720 4.222052
#> [13,] 4.478976 4.297090
#> [14,] 4.363803 4.479326
#> [15,] 4.864717 4.081164
#> [16,] 4.142596 4.332312
#> CACACAACAAGCGATG-500.2.2 CACACTCCAAGAAGAG-500.2.2
#> [1,] 4.308824 3.845771
#> [2,] 4.174837 4.474295
#> [3,] 4.290850 4.709784
#> [4,] 4.550654 4.822554
#> [5,] 4.723856 3.925373
#> [6,] 4.233660 4.393035
#> [7,] 4.065359 3.867330
#> [8,] 5.161765 4.527363
#> [9,] 4.468954 5.081260
#> [10,] 4.380719 4.842454
#> [11,] 4.388889 3.990050
#> [12,] 4.978758 4.398010
#> [13,] 4.240196 4.063018
#> [14,] 4.583333 3.847430
#> [15,] 4.186275 4.817579
#> [16,] 4.436275 3.975124
#> CACATAGAGCCAGAAC-500.2.2 CACATAGGTCATGCCG-500.2.2
#> [1,] 4.547794 4.415482
#> [2,] 4.025735 4.598736
#> [3,] 4.612132 4.704581
#> [4,] 4.084559 4.646130
#> [5,] 5.152574 4.545024
#> [6,] 5.137868 3.954186
#> [7,] 4.156250 4.162717
#> [8,] 5.045956 5.012638
#> [9,] 4.474265 4.402844
#> [10,] 4.365809 4.541864
#> [11,] 4.742647 4.537125
#> [12,] 4.494485 4.549763
#> [13,] 4.373162 4.282780
#> [14,] 4.645221 4.396524
#> [15,] 4.612132 4.353870
#> [16,] 5.036765 4.420221
#> CACCACTCATAAGACA-500.2.2 CAGCATAAGACACGAC-500.2.2
#> [1,] 4.332792 4.571651
#> [2,] 4.866883 4.453271
#> [3,] 4.517857 4.571651
#> [4,] 4.081169 4.157321
#> [5,] 4.019481 4.476636
#> [6,] 4.384740 3.772586
#> [7,] 4.275974 4.031153
#> [8,] 4.589286 5.015576
#> [9,] 4.230519 5.121495
#> [10,] 3.951299 3.956386
#> [11,] 4.493506 4.498442
#> [12,] 4.811688 4.468847
#> [13,] 4.202922 4.680685
#> [14,] 4.232143 4.454829
#> [15,] 4.259740 4.113707
#> [16,] 3.974026 4.436137
#> CAGCTGGAGAAACGAG-500.2.2 CATCCACCATGGAATA-500.2.2
#> [1,] 4.701937 4.288136
#> [2,] 4.314456 4.598305
#> [3,] 4.250373 4.318644
#> [4,] 4.590164 4.300000
#> [5,] 4.615499 4.600000
#> [6,] 4.254844 4.181356
#> [7,] 4.368107 4.528814
#> [8,] 4.697466 5.044068
#> [9,] 4.411326 4.893220
#> [10,] 4.497765 4.000000
#> [11,] 4.031297 4.449153
#> [12,] 4.344262 4.318644
#> [13,] 4.545455 4.133898
#> [14,] 4.466468 4.247458
#> [15,] 4.175857 4.303390
#> [16,] 4.639344 4.383051
#> CATGACAAGCAAATCA-500.2.2 CATGGCGCATGCCTTC-500.2.2
#> [1,] 4.563063 4.106713
#> [2,] 4.199700 4.650602
#> [3,] 4.369369 4.617900
#> [4,] 4.045045 4.055077
#> [5,] 4.639640 4.889845
#> [6,] 4.022523 4.876076
#> [7,] 4.072072 4.216867
#> [8,] 4.726727 4.733219
#> [9,] 4.876877 4.349398
#> [10,] 4.000000 4.631670
#> [11,] 4.081081 4.895009
#> [12,] 4.507508 4.686747
#> [13,] 5.000000 4.063683
#> [14,] 4.406907 4.358003
#> [15,] 4.084084 4.469880
#> [16,] 4.453453 4.826162
#> CATTCGCCATATGCTG-500.2.2 CCCTCCTTCACGCATA-500.2.2
#> [1,] 4.027473 4.111111
#> [2,] 4.476190 4.865900
#> [3,] 4.699634 4.752874
#> [4,] 3.970696 4.249042
#> [5,] 4.170330 4.178161
#> [6,] 4.016484 3.973180
#> [7,] 4.210623 4.409962
#> [8,] 4.794872 4.480843
#> [9,] 4.357143 4.873563
#> [10,] 4.177656 4.672414
#> [11,] 4.518315 4.250958
#> [12,] 4.489011 4.197318
#> [13,] 4.199634 4.455939
#> [14,] 4.637363 4.568966
#> [15,] 4.335165 4.559387
#> [16,] 4.452381 4.404215
#> CCTATTAAGTGTCCAT-500.2.2 CGATCGGCACATAACC-500.2.2
#> [1,] 4.693431 4.310811
#> [2,] 5.041971 4.333333
#> [3,] 4.625912 4.570571
#> [4,] 4.043796 4.546547
#> [5,] 4.288321 4.346847
#> [6,] 4.483577 4.258258
#> [7,] 4.516423 4.231231
#> [8,] 4.390511 4.852853
#> [9,] 4.000000 4.888889
#> [10,] 4.291971 4.303303
#> [11,] 4.658759 4.220721
#> [12,] 4.804745 4.334835
#> [13,] 4.428832 4.548048
#> [14,] 4.374088 4.596096
#> [15,] 3.742701 4.321321
#> [16,] 4.432482 4.022523
#> CGCCAAGGTGAGGCTA-500.2.2 CGCGGTATCTTTAGTC-500.2.2
#> [1,] 4.347741 4.648089
#> [2,] 4.583497 4.377389
#> [3,] 4.420432 4.791401
#> [4,] 4.933202 4.238854
#> [5,] 4.392927 4.060510
#> [6,] 4.294695 4.294586
#> [7,] 4.076621 3.737261
#> [8,] 4.903733 5.007962
#> [9,] 4.772102 4.691083
#> [10,] 4.379175 4.441083
#> [11,] 4.243615 4.272293
#> [12,] 4.412574 4.264331
#> [13,] 4.333988 4.417197
#> [14,] 4.174853 4.316879
#> [15,] 3.872299 4.227707
#> [16,] 3.919450 4.415605
#> CGGACTGTCGTCCGTT-500.2.2 CGGAGCTTCCTCAATT-500.2.2
#> [1,] 4.511834 4.451039
#> [2,] 3.931953 4.057864
#> [3,] 4.474852 4.673591
#> [4,] 4.501479 4.789318
#> [5,] 4.433432 3.830861
#> [6,] 4.670118 4.376855
#> [7,] 3.986686 4.256677
#> [8,] 4.875740 4.933234
#> [9,] 4.853550 4.820475
#> [10,] 4.142012 4.777448
#> [11,] 4.196746 4.065282
#> [12,] 4.362426 4.550445
#> [13,] 4.508876 4.166172
#> [14,] 4.362426 4.413947
#> [15,] 4.221893 4.062315
#> [16,] 4.483728 4.344214
#> CGGGTCATCGGCTTGG-500.2.2 CGGTTAACACGAAGCA-500.2.2
#> [1,] 3.971947 4.263393
#> [2,] 3.981848 4.071429
#> [3,] 4.173267 4.811012
#> [4,] 4.321782 4.135417
#> [5,] 4.179868 4.934524
#> [6,] 4.823432 4.537202
#> [7,] 3.721122 4.452381
#> [8,] 4.481848 4.782738
#> [9,] 4.780528 4.242560
#> [10,] 4.211221 4.480655
#> [11,] 3.945545 4.683036
#> [12,] 4.381188 4.654762
#> [13,] 4.165017 4.117560
#> [14,] 4.813531 4.261905
#> [15,] 3.948845 4.144345
#> [16,] 4.745875 4.525298
#> CGGTTAACATGAGCGA-500.2.2 CGTCAGGCACGGCTAC-500.2.2
#> [1,] 4.182085 4.758037
#> [2,] 4.563877 4.355330
#> [3,] 4.732746 4.350254
#> [4,] 4.073421 4.116751
#> [5,] 4.508076 4.703892
#> [6,] 3.964758 4.238579
#> [7,] 4.224670 4.021997
#> [8,] 4.753304 4.725888
#> [9,] 4.477239 4.842640
#> [10,] 4.452276 4.307953
#> [11,] 4.475771 3.957699
#> [12,] 4.572687 4.429780
#> [13,] 4.524229 5.027073
#> [14,] 4.268722 4.399323
#> [15,] 4.293686 4.250423
#> [16,] 4.283407 4.781726
#> CGTCCATCAAAGCGGT-500.2.2 CGTGTCTTCTACTATC-500.2.2
#> [1,] 4.598911 4.266314
#> [2,] 4.589837 4.679012
#> [3,] 4.470054 4.349206
#> [4,] 4.704174 4.190476
#> [5,] 5.134301 4.689594
#> [6,] 4.399274 3.955908
#> [7,] 4.431942 4.296296
#> [8,] 5.150635 4.657848
#> [9,] 4.658802 4.950617
#> [10,] 4.350272 4.910053
#> [11,] 4.266788 4.701940
#> [12,] 4.631579 4.416226
#> [13,] 4.446461 4.312169
#> [14,] 4.624319 4.338624
#> [15,] 4.315789 4.982363
#> [16,] 4.005445 4.061728
#> CTAAGACCACACCGCA-500.2.2 CTCGAGGCAGTTAACC-500.2.2
#> [1,] 4.246423 4.310287
#> [2,] 4.263911 4.384486
#> [3,] 4.456280 4.637437
#> [4,] 4.564388 4.327150
#> [5,] 4.448331 4.418212
#> [6,] 4.282989 3.978078
#> [7,] 4.187599 3.849916
#> [8,] 4.820350 4.571669
#> [9,] 4.478537 5.183811
#> [10,] 4.683625 5.220911
#> [11,] 4.379968 4.227656
#> [12,] 4.254372 4.087690
#> [13,] 3.915739 4.387858
#> [14,] 4.472178 4.330523
#> [15,] 4.135135 5.175379
#> [16,] 4.063593 4.344013
#> CTTAGGACACAAGACG-500.2.2 CTTGGCTCAGGTGCCT-500.2.2
#> [1,] 4.291822 4.098113
#> [2,] 4.137546 3.711321
#> [3,] 4.775093 4.067925
#> [4,] 4.085502 3.983019
#> [5,] 4.133829 4.073585
#> [6,] 4.189591 4.783019
#> [7,] 4.228625 3.741509
#> [8,] 4.667286 4.552830
#> [9,] 4.399628 4.475472
#> [10,] 4.087361 3.930189
#> [11,] 3.925651 4.183019
#> [12,] 4.576208 4.615094
#> [13,] 4.384758 4.235849
#> [14,] 4.565056 4.707547
#> [15,] 4.243494 4.066038
#> [16,] 4.685874 4.486792
#> CTTTGCGTCTGATTCT-500.2.2 GAACCTATCGTACCGG-500.2.2
#> [1,] 4.428571 4.376524
#> [2,] 4.147516 4.585366
#> [3,] 4.236025 4.550305
#> [4,] 4.265528 4.259146
#> [5,] 4.262422 4.841463
#> [6,] 4.911491 4.416159
#> [7,] 3.868012 4.144817
#> [8,] 4.771739 4.885671
#> [9,] 4.566770 4.179878
#> [10,] 4.352484 4.702744
#> [11,] 4.391304 4.460366
#> [12,] 4.436335 4.472561
#> [13,] 4.380435 4.347561
#> [14,] 5.012422 4.623476
#> [15,] 4.175466 4.275915
#> [16,] 4.931677 4.579268
#> GAATAAGCAAAGGTGC-500.2.2 GACACGCTCTGACCTC-500.2.2
#> [1,] 4.149477 4.397080
#> [2,] 4.547085 4.535766
#> [3,] 4.424514 4.268613
#> [4,] 4.328849 4.715328
#> [5,] 4.186846 4.388321
#> [6,] 4.197309 4.573723
#> [7,] 3.834081 4.319708
#> [8,] 4.744395 5.024818
#> [9,] 4.819133 4.272993
#> [10,] 4.408072 4.586861
#> [11,] 4.221226 4.416058
#> [12,] 4.206278 4.715328
#> [13,] 4.541106 4.468613
#> [14,] 4.221226 4.294891
#> [15,] 4.366218 4.140146
#> [16,] 4.153961 4.280292
#> GACCTGGCATCACAAC-500.2.2 GACGGCTCAGCTCGCA-500.2.2
#> [1,] 4.367347 4.326892
#> [2,] 3.947522 4.388084
#> [3,] 3.975219 5.125604
#> [4,] 3.973761 4.222222
#> [5,] 4.344023 4.478261
#> [6,] 4.829446 4.380032
#> [7,] 3.922741 4.352657
#> [8,] 4.645773 4.811594
#> [9,] 4.208455 4.367150
#> [10,] 3.969388 3.975845
#> [11,] 4.170554 4.523349
#> [12,] 4.374636 4.235105
#> [13,] 4.096210 4.318841
#> [14,] 4.680758 4.513688
#> [15,] 3.918367 4.259259
#> [16,] 4.495627 4.317230
#> GATCGCGTCCAGAGGA-500.2.2 GCAGCCAAGGGTCTCC-500.2.2
#> [1,] 4.567718 4.058480
#> [2,] 4.385900 4.244152
#> [3,] 4.513915 4.596491
#> [4,] 4.601113 4.282164
#> [5,] 4.087199 4.381579
#> [6,] 4.105751 4.942982
#> [7,] 3.886827 4.049708
#> [8,] 4.621521 4.519006
#> [9,] 4.562152 4.928363
#> [10,] 4.330241 4.045322
#> [11,] 4.491651 4.058480
#> [12,] 4.456401 4.317251
#> [13,] 4.560297 4.690058
#> [14,] 4.372913 4.625731
#> [15,] 4.085343 3.961988
#> [16,] 4.593692 4.771930
#> GCATGATTCGCCGTGA-500.2.2 GCCAAATTCGACGGAA-500.2.2
#> [1,] 4.467797 4.457295
#> [2,] 4.530508 3.960854
#> [3,] 4.455932 4.540925
#> [4,] 4.225424 4.300712
#> [5,] 4.808475 4.578292
#> [6,] 4.416949 3.914591
#> [7,] 4.177966 3.898577
#> [8,] 4.923729 4.969751
#> [9,] 5.001695 4.902135
#> [10,] 3.806780 3.637011
#> [11,] 4.435593 4.035587
#> [12,] 4.293220 4.480427
#> [13,] 4.081356 4.752669
#> [14,] 4.332203 4.637011
#> [15,] 4.213559 3.902135
#> [16,] 4.684746 4.387900
#> GCGCAGTCACAGGCCT-500.2.2 GCGCAGTGTCATCCCT-500.2.2
#> [1,] 4.758273 4.221441
#> [2,] 4.079137 4.184534
#> [3,] 4.812950 4.497364
#> [4,] 4.297842 4.590510
#> [5,] 4.650360 4.486819
#> [6,] 4.466187 4.706503
#> [7,] 4.433094 4.210896
#> [8,] 4.479137 4.794376
#> [9,] 4.447482 4.755712
#> [10,] 4.210072 4.833040
#> [11,] 4.654676 4.868190
#> [12,] 4.441727 4.335677
#> [13,] 4.097842 4.404218
#> [14,] 4.561151 4.565905
#> [15,] 4.227338 4.432337
#> [16,] 4.182734 4.472759
#> GCGCGATTCTGAGTGT-500.2.2 GGAATAAAGGCCCGTT-500.2.2
#> [1,] 4.547658 4.363958
#> [2,] 4.749596 4.772085
#> [3,] 4.893376 4.233216
#> [4,] 4.684976 4.565371
#> [5,] 4.227787 4.383392
#> [6,] 4.347334 4.515901
#> [7,] 3.945073 4.010601
#> [8,] 4.655897 4.756184
#> [9,] 4.287561 5.045936
#> [10,] 4.483037 4.844523
#> [11,] 4.242326 4.190813
#> [12,] 4.528271 4.220848
#> [13,] 4.618740 4.337456
#> [14,] 4.277868 4.120141
#> [15,] 4.119548 4.687279
#> [16,] 4.214863 4.353357
#> GGATTACAGTACACCT-500.2.2 GGATTACGTCGACTGC-500.2.2
#> [1,] 4.790429 4.667780
#> [2,] 4.143564 5.352254
#> [3,] 4.537954 4.505843
#> [4,] 4.183168 4.031720
#> [5,] 4.544554 4.293823
#> [6,] 4.019802 4.494157
#> [7,] 3.777228 4.063439
#> [8,] 4.744224 4.310518
#> [9,] 5.067657 4.258765
#> [10,] 4.391089 4.101836
#> [11,] 4.353135 4.489149
#> [12,] 4.594059 4.844741
#> [13,] 4.691419 4.535893
#> [14,] 4.156766 4.402337
#> [15,] 3.970297 4.233723
#> [16,] 4.724422 4.045075
#> GGCGTGTGTCTTCGTC-500.2.2 GGTATTGCACATCCAA-500.2.2
#> [1,] 4.344294 4.260204
#> [2,] 4.218569 4.678571
#> [3,] 4.334623 4.704082
#> [4,] 4.160542 4.431973
#> [5,] 4.692456 4.261905
#> [6,] 3.895551 4.377551
#> [7,] 4.272727 4.011905
#> [8,] 4.891683 4.705782
#> [9,] 4.437137 4.328231
#> [10,] 3.961315 4.561224
#> [11,] 4.172147 4.586735
#> [12,] 4.537718 4.693878
#> [13,] 5.106383 4.683673
#> [14,] 4.206963 4.197279
#> [15,] 3.957447 3.952381
#> [16,] 4.441006 4.265306
#> GGTGAAGGTAAAGTCA-500.2.2 GTAGTCAAGACAGGCT-500.2.2
#> [1,] 4.758007 4.116667
#> [2,] 4.234875 4.572222
#> [3,] 4.213523 4.270370
#> [4,] 3.864769 4.587037
#> [5,] 5.053381 4.581481
#> [6,] 4.185053 4.107407
#> [7,] 4.161922 4.166667
#> [8,] 4.902135 5.262963
#> [9,] 5.138790 4.920370
#> [10,] 3.971530 4.077778
#> [11,] 4.425267 4.264815
#> [12,] 4.669039 4.355556
#> [13,] 4.626335 4.503704
#> [14,] 4.288256 4.644444
#> [15,] 3.786477 4.001852
#> [16,] 4.720641 4.348148
#> GTAGTCACAGTACACT-500.2.2 GTCACAAAGAGGGCTT-500.2.2
#> [1,] 4.511905 4.341837
#> [2,] 4.222222 4.166667
#> [3,] 4.575397 4.333333
#> [4,] 4.313492 5.032313
#> [5,] 4.434524 4.335034
#> [6,] 4.297619 4.346939
#> [7,] 4.420635 3.996599
#> [8,] 4.839286 4.986395
#> [9,] 4.503968 4.940476
#> [10,] 4.755952 4.831633
#> [11,] 4.551587 3.989796
#> [12,] 4.329365 4.384354
#> [13,] 4.388889 4.479592
#> [14,] 4.583333 4.508503
#> [15,] 4.396825 4.600340
#> [16,] 4.365079 3.943878
#> GTCCTCATCCCTGACT-500.2.2 GTCGTAACAGCTGTAT-500.2.2
#> [1,] 4.683801 4.323296
#> [2,] 4.032710 4.109350
#> [3,] 4.517134 4.714739
#> [4,] 4.207165 4.557845
#> [5,] 4.576324 4.258320
#> [6,] 4.395639 4.481775
#> [7,] 3.948598 4.228209
#> [8,] 4.915888 4.667195
#> [9,] 4.475078 5.207607
#> [10,] 4.221184 4.258320
#> [11,] 4.272586 4.220285
#> [12,] 4.406542 4.421553
#> [13,] 4.693146 4.274168
#> [14,] 4.538941 4.503962
#> [15,] 4.350467 4.348653
#> [16,] 4.390966 4.442155
#> GTCGTAACATACGCCG-500.2.2 GTCTCGTCAACGCACC-500.2.2
#> [1,] 3.990291 4.632219
#> [2,] 4.177994 4.436170
#> [3,] 4.716828 4.054711
#> [4,] 4.614887 4.437690
#> [5,] 4.466019 4.297872
#> [6,] 4.302589 4.360182
#> [7,] 4.168285 4.004559
#> [8,] 5.045307 4.775076
#> [9,] 4.692557 4.531915
#> [10,] 4.427184 4.490881
#> [11,] 4.461165 4.141337
#> [12,] 4.477346 4.218845
#> [13,] 4.300971 4.200608
#> [14,] 4.338188 4.151976
#> [15,] 4.056634 4.376900
#> [16,] 4.681230 4.325228
#> GTCTCGTGTTGATTGC-500.2.2 GTGCATATCCTCATTA-500.2.2
#> [1,] 4.579639 4.199288
#> [2,] 3.852217 3.857651
#> [3,] 4.515599 4.325623
#> [4,] 3.934319 4.364769
#> [5,] 4.293924 4.400356
#> [6,] 4.610837 4.647687
#> [7,] 4.297209 4.067616
#> [8,] 4.839080 4.297153
#> [9,] 4.356322 4.653025
#> [10,] 4.203612 4.298932
#> [11,] 4.192118 4.279359
#> [12,] 4.394089 4.297153
#> [13,] 4.425287 4.099644
#> [14,] 4.257800 4.866548
#> [15,] 4.215107 4.080071
#> [16,] 4.500821 4.784698
#> GTGTTAGTCATGCTCC-500.2.2 GTTAAGCGTAGAGCTG-500.2.2
#> [1,] 4.499058 4.597134
#> [2,] 4.578154 4.369427
#> [3,] 4.380414 4.603503
#> [4,] 4.056497 4.237261
#> [5,] 4.634652 4.815287
#> [6,] 4.269303 4.356688
#> [7,] 4.395480 4.455414
#> [8,] 5.079096 4.562102
#> [9,] 4.819209 4.750000
#> [10,] 4.015066 4.256369
#> [11,] 4.084746 4.345541
#> [12,] 4.444444 4.585987
#> [13,] 4.920904 4.689490
#> [14,] 4.378531 4.205414
#> [15,] 4.216573 3.939490
#> [16,] 4.853107 4.175159
#> GTTCGGGAGCTACCGC-500.2.2 TACACGACACCGAAAG-500.2.2
#> [1,] 4.357245 4.338374
#> [2,] 3.845050 4.470699
#> [3,] 4.497848 4.667297
#> [4,] 4.340029 4.168242
#> [5,] 4.238164 4.746692
#> [6,] 4.827834 4.103970
#> [7,] 3.919656 4.192817
#> [8,] 4.407461 4.969754
#> [9,] 4.505022 4.410208
#> [10,] 4.134864 4.281664
#> [11,] 4.109039 4.175803
#> [12,] 4.737446 4.570888
#> [13,] 4.347202 4.627599
#> [14,] 4.694405 4.491493
#> [15,] 4.238164 3.984877
#> [16,] 4.826399 4.355388
#> TACAGTGCAAGCGTAG-500.2.2 TACCTATTCCAGAGGA-500.2.2
#> [1,] 4.111307 4.431304
#> [2,] 4.335689 3.961739
#> [3,] 4.952297 4.387826
#> [4,] 4.210247 4.194783
#> [5,] 4.408127 4.586087
#> [6,] 4.401060 4.766957
#> [7,] 4.441696 4.170435
#> [8,] 4.623675 4.794783
#> [9,] 4.602473 4.579130
#> [10,] 4.252650 4.038261
#> [11,] 4.355124 4.561739
#> [12,] 4.418728 4.299130
#> [13,] 4.259717 4.353043
#> [14,] 4.098940 4.699130
#> [15,] 4.245583 3.876522
#> [16,] 4.383392 4.692174
#> TACTTACGTCAAGCGA-500.2.2 TAGTGGTTCTCTGCTG-500.2.2
#> [1,] 4.520548 4.166922
#> [2,] 4.547945 4.471669
#> [3,] 4.522505 4.563553
#> [4,] 4.285714 4.534456
#> [5,] 4.592955 4.104135
#> [6,] 4.457926 4.105666
#> [7,] 4.099804 4.289433
#> [8,] 4.592955 4.661562
#> [9,] 4.530333 4.586524
#> [10,] 4.473581 4.509954
#> [11,] 4.254403 4.369066
#> [12,] 5.027397 4.385911
#> [13,] 4.289628 4.416539
#> [14,] 4.422701 4.395100
#> [15,] 4.769080 4.091884
#> [16,] 4.579256 4.266462
#> TCAACGATCACGATGT-500.2.2 TCAATCTAGGATGGAA-500.2.2
#> [1,] 4.460949 4.814985
#> [2,] 4.526799 4.541284
#> [3,] 4.624809 4.594801
#> [4,] 4.542113 4.553517
#> [5,] 4.767228 4.457187
#> [6,] 4.421133 4.582569
#> [7,] 4.281776 4.224771
#> [8,] 4.790199 5.113150
#> [9,] 4.462481 4.238532
#> [10,] 4.379786 4.227829
#> [11,] 4.661562 4.042813
#> [12,] 4.346095 4.474006
#> [13,] 4.052067 4.501529
#> [14,] 4.234303 4.010703
#> [15,] 4.281776 4.587156
#> [16,] 4.162328 4.226300
#> TCAGCTCTCGTGGGAA-500.2.2 TCGTACCAGCATGGCA-500.2.2
#> [1,] 4.727575 4.196944
#> [2,] 4.367110 4.076401
#> [3,] 4.387043 4.432937
#> [4,] 4.529900 4.200340
#> [5,] 4.888704 4.940577
#> [6,] 4.159468 4.926995
#> [7,] 4.300664 4.183362
#> [8,] 5.164452 4.989813
#> [9,] 4.813953 3.894737
#> [10,] 4.139535 4.555178
#> [11,] 4.303987 4.611205
#> [12,] 4.720930 4.363328
#> [13,] 4.516611 4.449915
#> [14,] 4.480066 4.091681
#> [15,] 4.034884 4.365025
#> [16,] 4.368771 4.611205
#> TCTGGAAAGCGATGAC-500.2.2 TGAAAGATCCGGCACA-500.2.2
#> [1,] 4.693805 4.377713
#> [2,] 4.415929 4.159190
#> [3,] 4.492035 4.507959
#> [4,] 4.757522 4.143271
#> [5,] 4.552212 4.280753
#> [6,] 4.410619 4.675832
#> [7,] 4.451327 4.017366
#> [8,] 5.001770 4.914616
#> [9,] 4.400000 4.698987
#> [10,] 4.182301 4.018813
#> [11,] 4.348673 4.056440
#> [12,] 4.336283 4.445731
#> [13,] 4.355752 4.205499
#> [14,] 4.146903 4.672938
#> [15,] 3.987611 4.078148
#> [16,] 4.346903 5.056440
#> TGACTTTAGGCTCTTA-500.2.2 TGACTTTGTACATCCA-500.2.2
#> [1,] 4.424188 4.094961
#> [2,] 4.326715 4.472868
#> [3,] 4.451264 4.246124
#> [4,] 4.220217 4.711240
#> [5,] 4.093863 4.164729
#> [6,] 4.205776 3.984496
#> [7,] 3.718412 4.178295
#> [8,] 4.599278 4.436047
#> [9,] 4.433213 4.742248
#> [10,] 4.160650 5.104651
#> [11,] 4.444043 4.383721
#> [12,] 4.530686 4.406977
#> [13,] 4.731047 4.178295
#> [14,] 4.202166 4.660853
#> [15,] 4.527076 5.021318
#> [16,] 4.416968 4.286822
#> TGAGAGGAGTTCGCGC-500.2.2 TGATTTCAGTGCCAGA-500.2.2
#> [1,] 4.351714 4.199219
#> [2,] 4.688525 4.220703
#> [3,] 4.718331 4.701172
#> [4,] 4.444113 4.775391
#> [5,] 4.745156 4.390625
#> [6,] 4.095380 4.208984
#> [7,] 4.222057 4.396484
#> [8,] 4.664680 4.552734
#> [9,] 4.690015 4.445312
#> [10,] 4.278689 4.193359
#> [11,] 4.223547 4.400391
#> [12,] 4.137109 4.195312
#> [13,] 4.651267 4.535156
#> [14,] 4.274218 4.582031
#> [15,] 4.183308 3.996094
#> [16,] 4.344262 4.230469
#> TGTGTTTCAGTGAGTG-500.2.2 TGTTCCGCACGGTGTC-500.2.2
#> [1,] 4.508803 4.258592
#> [2,] 4.114437 4.276596
#> [3,] 4.283451 4.657938
#> [4,] 4.357394 4.409165
#> [5,] 4.598592 4.302782
#> [6,] 4.382042 3.931260
#> [7,] 3.970070 4.140753
#> [8,] 4.808099 4.998363
#> [9,] 4.401408 4.870704
#> [10,] 4.054577 3.986907
#> [11,] 4.411972 4.615385
#> [12,] 4.579225 4.389525
#> [13,] 4.353873 4.394435
#> [14,] 4.494718 4.363339
#> [15,] 4.137324 3.962357
#> [16,] 4.117958 4.689034
#> TTAGGCAAGACATAAC-500.2.2 TTTACTGTCAGGTTCA-500.2.2
#> [1,] 4.470489 4.247485
#> [2,] 4.463744 4.213280
#> [3,] 4.495784 4.450704
#> [4,] 4.435076 4.106640
#> [5,] 4.516020 4.494970
#> [6,] 4.050590 4.231388
#> [7,] 4.499157 4.331992
#> [8,] 4.893761 4.694165
#> [9,] 4.499157 4.800805
#> [10,] 4.688027 4.046278
#> [11,] 4.421585 4.309859
#> [12,] 4.640809 4.394366
#> [13,] 4.172007 4.406439
#> [14,] 4.470489 3.828974
#> [15,] 4.355818 4.537223
#> [16,] 4.495784 4.480885
#> TTTGGTTCACAGCGTC-500.2.2 AACCATGCAGTCTTCC-r17 AACCGCGTCGGACAAG-r17
#> [1,] 4.437970 4.261343 4.342988
#> [2,] 4.319549 4.326679 4.629573
#> [3,] 4.584586 4.569873 4.158537
#> [4,] 4.719925 4.176044 4.272866
#> [5,] 4.701128 4.471869 5.234756
#> [6,] 4.233083 4.185118 3.922256
#> [7,] 3.968045 4.457350 4.263720
#> [8,] 4.719925 4.671506 4.704268
#> [9,] 4.464286 4.373866 4.126524
#> [10,] 4.242481 4.181488 4.295732
#> [11,] 4.327068 3.970962 3.974085
#> [12,] 4.409774 4.421053 4.342988
#> [13,] 4.603383 4.337568 4.303354
#> [14,] 4.204887 4.261343 4.388720
#> [15,] 4.026316 4.357532 4.219512
#> [16,] 4.426692 4.444646 4.414634
#> CGAGAAGAGTGGGATC-r17 CTTGGCTAGGTGTGGT-r17 GCAAACTTCCCGACTT-r17
#> [1,] 4.153355 4.622901 4.222222
#> [2,] 4.084665 4.421374 4.295082
#> [3,] 4.223642 4.435115 4.322404
#> [4,] 4.073482 4.480916 4.054645
#> [5,] 4.448882 4.433588 4.229508
#> [6,] 3.958466 4.306870 4.395264
#> [7,] 4.178914 4.716031 4.220401
#> [8,] 4.137380 4.422901 4.249545
#> [9,] 4.047923 4.772519 4.469945
#> [10,] 4.327476 4.067176 4.302368
#> [11,] 3.905751 4.270229 4.346084
#> [12,] 4.230032 4.577099 4.426230
#> [13,] 4.295527 4.232061 4.194900
#> [14,] 4.153355 4.549618 4.524590
#> [15,] 4.076677 4.312977 4.351548
#> [16,] 4.528754 4.761832 4.568306
#> GGGAATGAGTGGTAAT-r17 GTTACAGAGAAGCCCA-r17 TTAGGCAGTCACCTAA-r17
#> [1,] 4.344231 4.204301 4.120482
#> [2,] 3.928846 4.225806 4.213855
#> [3,] 4.367308 4.050179 4.004518
#> [4,] 4.463462 4.290323 4.447289
#> [5,] 4.319231 4.732975 4.353916
#> [6,] 4.213462 3.896057 3.736446
#> [7,] 4.569231 4.428315 4.442771
#> [8,] 4.801923 4.514337 4.599398
#> [9,] 4.388462 4.519713 4.170181
#> [10,] 4.171154 4.729391 4.073795
#> [11,] 4.373077 4.283154 4.308735
#> [12,] 4.042308 4.159498 4.087349
#> [13,] 4.221154 4.987455 4.262048
#> [14,] 4.255769 4.132616 4.201807
#> [15,] 4.234615 3.998208 4.195783
#> [16,] 4.167308 4.464158 4.076807
#> AAAGTAGCATTGAGCT-b01 AAATGCCAGGACAGAA-b01 AACCATGAGTGTACCT-b01
#> [1,] 4.419628 4.626168 4.540541
#> [2,] 3.901861 4.444860 4.240064
#> [3,] 4.328257 4.151402 4.198728
#> [4,] 4.512690 4.097196 4.131955
#> [5,] 4.571912 5.009346 4.817170
#> [6,] 4.546531 4.186916 4.294118
#> [7,] 4.365482 4.190654 4.106518
#> [8,] 4.879865 4.659813 5.100159
#> [9,] 4.578680 4.721495 4.847377
#> [10,] 4.067682 4.140187 3.901431
#> [11,] 4.450085 4.330841 4.103339
#> [12,] 4.087986 4.244860 4.567568
#> [13,] 4.049069 4.833645 4.965024
#> [14,] 4.532995 4.237383 4.405405
#> [15,] 4.192893 3.863551 4.119237
#> [16,] 4.443316 4.400000 4.352941
#> AACGTTGCAGTTCATG-b01 AACTCTTGTCTGCCAG-b01 AACTTTCCACGCATCG-b01
#> [1,] 4.467153 4.623239 4.142045
#> [2,] 4.332847 4.339789 4.119318
#> [3,] 4.427737 4.156690 4.640152
#> [4,] 4.205839 5.042254 4.346591
#> [5,] 4.700730 4.350352 4.625000
#> [6,] 4.845255 4.475352 4.100379
#> [7,] 3.967883 4.542254 4.214015
#> [8,] 5.113869 4.672535 4.895833
#> [9,] 4.343066 4.362676 4.820076
#> [10,] 4.322628 4.017606 4.397727
#> [11,] 4.643796 3.978873 4.611742
#> [12,] 4.532847 4.383803 4.651515
#> [13,] 4.030657 4.075704 4.702652
#> [14,] 4.251095 4.197183 4.320076
#> [15,] 4.680292 4.477113 4.282197
#> [16,] 4.061314 4.117958 4.473485
#> AAGTCTGGTCGGCATC-b01 AATCGGTCATACTACG-b01 AATCGGTTCTGTCAAG-b01
#> [1,] 4.578947 5.052448 4.446841
#> [2,] 4.143725 4.669580 4.206471
#> [3,] 4.374494 4.583916 4.342065
#> [4,] 4.473684 4.603147 4.727273
#> [5,] 4.323887 4.580420 4.419106
#> [6,] 3.981781 4.222028 4.032357
#> [7,] 4.564777 4.141608 4.100154
#> [8,] 4.902834 4.548951 5.124807
#> [9,] 4.599190 3.956294 4.795069
#> [10,] 4.550607 4.695804 4.526965
#> [11,] 4.066802 4.340909 4.298921
#> [12,] 3.963563 4.379371 4.295840
#> [13,] 4.844130 4.611888 4.511556
#> [14,] 3.870445 4.414336 4.557781
#> [15,] 4.198381 4.171329 4.183359
#> [16,] 4.147773 4.125874 3.981510
#> ACAGCTACACCAACCG-b01 ACCGTAACATGCCACG-b01 ACCGTAAGTGAGGGAG-b01
#> [1,] 4.224458 4.935484 4.199656
#> [2,] 4.216718 4.003072 4.192771
#> [3,] 4.181115 4.027650 4.511188
#> [4,] 4.614551 3.981567 4.244406
#> [5,] 4.069659 5.105991 4.185886
#> [6,] 4.425697 3.918587 3.721170
#> [7,] 4.137771 4.537634 4.395869
#> [8,] 5.289474 4.491551 5.499139
#> [9,] 4.820433 4.119816 4.600688
#> [10,] 4.267802 3.606759 4.068847
#> [11,] 4.527864 3.749616 4.321859
#> [12,] 4.588235 4.029186 4.235800
#> [13,] 4.447368 4.291859 4.211704
#> [14,] 4.682663 4.175115 4.363167
#> [15,] 3.984520 4.325653 3.874355
#> [16,] 4.484520 4.064516 4.473322
#> ACGAGGACATGGTCAT-b01 ACGATGTAGGCGCTCT-b01 ACTGAACGTTGAGTTC-b01
#> [1,] 4.201031 4.537464 4.320557
#> [2,] 4.563574 4.260807 4.257840
#> [3,] 4.536082 4.631124 4.313589
#> [4,] 4.503436 4.432277 4.026132
#> [5,] 4.487973 4.818444 4.128920
#> [6,] 4.360825 4.478386 4.388502
#> [7,] 4.211340 4.246398 4.005226
#> [8,] 4.893471 5.253602 5.353659
#> [9,] 4.604811 4.684438 4.822300
#> [10,] 3.984536 4.159942 4.743902
#> [11,] 4.616838 4.508646 4.142857
#> [12,] 4.170103 4.631124 4.263066
#> [13,] 4.436426 3.704611 4.372822
#> [14,] 4.159794 4.350144 4.466899
#> [15,] 4.300687 4.649856 4.409408
#> [16,] 4.579038 4.363112 4.008711
#> ACTGAGTAGTGGAGTC-b01 ACTGCTCCACGTTGGC-b01 ACTTACTCACATGACT-b01
#> [1,] 4.259684 4.628676 4.734440
#> [2,] 4.477762 4.215074 4.190871
#> [3,] 4.459110 4.545956 4.688797
#> [4,] 4.573888 4.750000 4.139004
#> [5,] 4.622669 4.356618 4.512448
#> [6,] 4.179340 4.341912 4.058091
#> [7,] 4.497848 3.994485 4.373444
#> [8,] 4.840746 4.843750 4.950207
#> [9,] 4.563845 4.470588 4.576763
#> [10,] 4.625538 4.492647 3.931535
#> [11,] 4.624103 4.615809 3.850622
#> [12,] 4.698709 4.400735 4.246888
#> [13,] 4.398852 4.485294 4.595436
#> [14,] 4.410330 4.443015 3.970954
#> [15,] 4.832138 4.042279 4.006224
#> [16,] 4.426112 4.512868 4.624481
#> ACTTGTTAGTCGATAA-b01 ACTTGTTTCTTGAGAC-b01 AGAGCTTAGGTGGGTT-b01
#> [1,] 4.769726 4.316558 4.343580
#> [2,] 4.576490 4.032468 4.251356
#> [3,] 4.478261 4.321429 4.484629
#> [4,] 3.898551 4.530844 3.942134
#> [5,] 4.347826 4.620130 4.529837
#> [6,] 4.173913 4.152597 4.144665
#> [7,] 4.325282 4.159091 4.444846
#> [8,] 4.998390 5.089286 4.732369
#> [9,] 4.502415 4.827922 4.412297
#> [10,] 3.993559 4.318182 4.433996
#> [11,] 4.172303 4.425325 4.345389
#> [12,] 4.402576 4.254870 4.320072
#> [13,] 4.584541 4.355519 4.972875
#> [14,] 4.578100 4.913961 4.403255
#> [15,] 4.389694 4.387987 4.218807
#> [16,] 4.154589 4.435065 4.799277
#> AGAGCTTGTTAGGGTG-b01 AGATTGCTCCGAGCCA-b01 AGCATACTCGACGGAA-b01
#> [1,] 4.299559 4.279940 4.333898
#> [2,] 3.892805 4.643713 4.477966
#> [3,] 3.975037 4.510479 4.788136
#> [4,] 4.209985 4.459581 4.427119
#> [5,] 4.820852 4.654192 4.257627
#> [6,] 4.132159 4.104790 4.259322
#> [7,] 4.468429 4.200599 4.227119
#> [8,] 4.907489 4.943114 4.969492
#> [9,] 4.427313 4.625749 4.774576
#> [10,] 3.950073 4.375749 4.152542
#> [11,] 4.091043 4.202096 4.393220
#> [12,] 3.969163 4.525449 4.598305
#> [13,] 4.544787 4.425150 4.449153
#> [14,] 4.468429 4.742515 4.316949
#> [15,] 3.850220 4.218563 4.140678
#> [16,] 4.472834 4.465569 4.657627
#> AGCATACTCGAGGTAG-b01 AGCGTATCATATGAGA-b01 AGCGTATGTGCCTGTG-b01
#> [1,] 4.328467 4.747475 4.248473
#> [2,] 4.194161 4.526936 4.460285
#> [3,] 4.150365 4.087542 4.446029
#> [4,] 4.398540 4.217172 4.645621
#> [5,] 4.750365 4.388889 4.535642
#> [6,] 4.058394 4.304714 4.154786
#> [7,] 3.950365 4.095960 4.566191
#> [8,] 4.800000 4.996633 4.633401
#> [9,] 4.684672 4.870370 4.596741
#> [10,] 4.687591 4.353535 4.346232
#> [11,] 4.289051 4.240741 4.441955
#> [12,] 4.163504 4.281145 4.492872
#> [13,] 4.915328 4.754209 4.331976
#> [14,] 4.072993 4.382155 4.124236
#> [15,] 4.080292 4.385522 4.309572
#> [16,] 4.035036 4.252525 4.653768
#> AGCGTCGTCGGCGGTT-b01 AGCTCTCGTCTCCCTA-b01 AGGCCACCAGGACGTA-b01
#> [1,] 4.477134 4.252006 4.432551
#> [2,] 4.109756 4.431782 4.376833
#> [3,] 4.256098 4.823435 4.398827
#> [4,] 4.445122 4.296950 4.486804
#> [5,] 4.530488 4.380417 4.331378
#> [6,] 4.286585 4.048154 4.309384
#> [7,] 4.236280 4.402889 4.467742
#> [8,] 5.059451 4.825040 5.124633
#> [9,] 4.594512 4.980738 4.306452
#> [10,] 4.167683 4.149278 4.475073
#> [11,] 4.163110 4.524880 4.049853
#> [12,] 4.760671 4.712681 4.151026
#> [13,] 4.423780 4.269663 4.310850
#> [14,] 4.333841 4.558587 4.042522
#> [15,] 4.146341 4.046549 4.247801
#> [16,] 4.346037 4.662921 4.200880
#> AGGCCACTCCTGCAGG-b01 AGGGATGGTCTTCAAG-b01 AGTCTTTCAAGCCATT-b01
#> [1,] 4.638333 4.574675 4.584348
#> [2,] 4.803333 4.480519 4.622609
#> [3,] 4.138333 3.993506 4.126957
#> [4,] 4.290000 4.287338 4.302609
#> [5,] 4.405000 4.451299 4.540870
#> [6,] 4.438333 4.647727 4.422609
#> [7,] 3.946667 4.251623 4.165217
#> [8,] 4.965000 4.563312 5.107826
#> [9,] 4.291667 4.311688 4.278261
#> [10,] 4.516667 4.983766 4.514783
#> [11,] 4.331667 4.155844 4.196522
#> [12,] 4.451667 4.465909 4.062609
#> [13,] 4.505000 4.529221 4.347826
#> [14,] 4.051667 4.285714 4.443478
#> [15,] 4.093333 3.702922 4.194783
#> [16,] 4.336667 3.969156 4.318261
#> AGTCTTTTCCCTAACC-b01 AGTGAGGAGGATGCGT-b01 ATCACGACAGATCCAT-b01
#> [1,] 4.376582 4.345455 4.100529
#> [2,] 4.446203 4.343939 4.474427
#> [3,] 4.172468 4.503030 4.532628
#> [4,] 4.493671 4.731818 4.068783
#> [5,] 4.746835 4.304545 4.384480
#> [6,] 4.123418 4.357576 4.082892
#> [7,] 4.291139 4.487879 4.282187
#> [8,] 4.927215 4.775758 5.232804
#> [9,] 4.731013 4.896970 4.574956
#> [10,] 4.449367 4.237879 4.044092
#> [11,] 4.590190 4.478788 4.391534
#> [12,] 4.664557 4.659091 4.463845
#> [13,] 4.242089 4.487879 4.125220
#> [14,] 4.178797 4.481818 4.045855
#> [15,] 4.617089 4.321212 4.326279
#> [16,] 4.311709 4.560606 4.093474
#> ATCACGATCCTCAACC-b01 ATCTACTGTAAAGTCA-b01 ATTATCCGTACCATCA-b01
#> [1,] 4.179525 4.496337 4.313462
#> [2,] 4.422849 3.998168 4.348077
#> [3,] 4.686944 4.628205 4.640385
#> [4,] 3.759644 4.216117 4.244231
#> [5,] 4.519288 4.584249 4.071154
#> [6,] 4.189911 4.247253 4.425000
#> [7,] 4.314540 4.364469 4.190385
#> [8,] 4.908012 4.771062 4.794231
#> [9,] 4.663205 4.536630 4.813462
#> [10,] 4.109792 4.282051 4.109615
#> [11,] 4.422849 4.223443 4.228846
#> [12,] 4.293769 4.326007 4.490385
#> [13,] 4.172107 4.201465 4.492308
#> [14,] 4.225519 4.772894 4.305769
#> [15,] 4.324926 4.082418 4.417308
#> [16,] 4.293769 4.445055 4.301923
#> ATTATCCGTGTGGCTC-b01 ATTGGACGTTAGAACA-b01 ATTTCTGTCCCGACTT-b01
#> [1,] 4.782353 4.075926 4.162950
#> [2,] 4.523529 4.188889 4.449400
#> [3,] 4.401961 4.429630 4.545455
#> [4,] 4.260784 4.744444 4.229846
#> [5,] 4.925490 4.612963 4.449400
#> [6,] 4.694118 4.098148 4.000000
#> [7,] 4.207843 3.970370 4.180103
#> [8,] 5.000000 4.798148 4.831904
#> [9,] 4.152941 4.464815 4.905660
#> [10,] 4.303922 4.396296 4.245283
#> [11,] 4.580392 4.381481 4.449400
#> [12,] 4.629412 4.696296 4.500858
#> [13,] 4.592157 4.392593 4.296741
#> [14,] 4.382353 3.850000 4.660377
#> [15,] 4.241176 4.344444 4.102916
#> [16,] 4.456863 4.194444 4.174957
#> CAACTAGTCAAGAAGT-b01 CAAGAAAAGCCAGAAC-b01 CACAGGCAGTATGACA-b01
#> [1,] 4.336449 4.368585 3.942804
#> [2,] 4.087850 4.161742 4.398524
#> [3,] 4.635514 4.732504 3.839483
#> [4,] 4.072897 4.590980 4.398524
#> [5,] 4.229907 4.520995 3.998155
#> [6,] 4.143925 4.538103 4.339483
#> [7,] 4.256075 4.415241 4.306273
#> [8,] 5.171963 4.981337 5.040590
#> [9,] 4.592523 4.508554 4.743542
#> [10,] 4.310280 4.362364 4.721402
#> [11,] 4.231776 4.270607 4.193727
#> [12,] 4.143925 4.511664 4.498155
#> [13,] 4.328972 4.289269 4.134686
#> [14,] 4.373832 4.609642 4.236162
#> [15,] 4.188785 4.287714 5.012915
#> [16,] 4.407477 4.233281 4.278598
#> CACATAGGTGTGACGA-b01 CACCACTAGGGAGTAA-b01 CACCACTCAAAGAATC-b01
#> [1,] 4.509677 4.372742 4.003091
#> [2,] 4.433871 4.527094 4.522411
#> [3,] 4.279032 4.569787 4.259660
#> [4,] 4.348387 4.610837 4.435858
#> [5,] 4.114516 4.760263 4.029366
#> [6,] 3.996774 4.141215 4.205564
#> [7,] 4.332258 4.377668 4.437403
#> [8,] 4.888710 5.218391 5.234930
#> [9,] 4.991935 4.305419 4.697063
#> [10,] 4.587097 4.216749 5.095827
#> [11,] 4.870968 4.428571 4.166924
#> [12,] 4.383871 4.459770 4.299845
#> [13,] 4.341935 4.282430 3.914992
#> [14,] 4.419355 4.259442 4.327666
#> [15,] 4.522581 4.331691 4.642968
#> [16,] 4.248387 4.011494 3.938176
#> CACCACTTCGTAGGAG-b01 CAGAATCAGCGACGTA-b01 CAGATCAAGATGTCGG-b01
#> [1,] 4.272436 4.311649 4.538462
#> [2,] 4.554487 4.236006 4.289689
#> [3,] 4.405449 4.226929 4.432079
#> [4,] 4.323718 4.391831 3.931260
#> [5,] 4.751603 4.205749 4.019640
#> [6,] 4.644231 4.267776 3.891980
#> [7,] 4.411859 4.226929 4.134206
#> [8,] 5.272436 4.768533 5.139116
#> [9,] 4.464744 4.978820 4.739771
#> [10,] 4.895833 4.242057 4.098200
#> [11,] 4.288462 4.568835 4.094926
#> [12,] 5.070513 4.490166 4.599018
#> [13,] 4.317308 4.167927 4.710311
#> [14,] 4.342949 4.632375 4.276596
#> [15,] 4.285256 4.387292 4.122750
#> [16,] 4.141026 4.397882 4.392799
#> CAGCCGATCGTCACGG-b01 CAGGTGCCATGCAACT-b01 CAGTCCTCAGCCTTGG-b01
#> [1,] 4.448214 4.282468 4.515947
#> [2,] 4.076786 4.336039 4.315197
#> [3,] 4.375000 4.550325 4.564728
#> [4,] 4.503571 4.603896 4.080675
#> [5,] 4.648214 4.258117 4.752345
#> [6,] 3.817857 4.405844 4.288931
#> [7,] 4.185714 4.332792 4.223265
#> [8,] 4.950000 4.819805 5.307692
#> [9,] 4.558929 4.724026 5.146341
#> [10,] 4.546429 4.314935 4.016886
#> [11,] 4.282143 4.555195 4.322702
#> [12,] 4.625000 4.323052 4.362101
#> [13,] 5.141071 4.180195 4.574109
#> [14,] 4.042857 4.371753 4.502814
#> [15,] 4.189286 4.271104 3.962477
#> [16,] 4.571429 4.357143 4.470919
#> CATCAGATCCGTAGTA-b01 CATCGAACATGGTCTA-b01 CATCGAAGTCAACTGT-b01
#> [1,] 4.013817 4.020243 4.533333
#> [2,] 4.167530 3.910931 4.129412
#> [3,] 4.322971 4.263158 4.233333
#> [4,] 4.402418 4.350202 4.260784
#> [5,] 4.032815 4.607287 4.278431
#> [6,] 4.031088 3.864372 4.329412
#> [7,] 4.027634 4.686235 4.149020
#> [8,] 4.892919 5.000000 4.839216
#> [9,] 4.974093 4.457490 4.380392
#> [10,] 4.077720 4.340081 3.901961
#> [11,] 4.207254 4.421053 4.190196
#> [12,] 4.312608 4.591093 3.976471
#> [13,] 4.347150 4.441296 4.668627
#> [14,] 4.658031 4.115385 3.847059
#> [15,] 4.376511 4.259109 3.792157
#> [16,] 4.231434 4.746964 4.292157
#> CATTCGCGTTGAGGTG-b01 CCGGTAGAGTAGGCCA-b01 CCGTTCAAGAGTCTGG-b01
#> [1,] 4.144954 4.362654 4.269891
#> [2,] 4.623853 4.208333 4.287051
#> [3,] 4.944954 4.368827 4.815913
#> [4,] 4.627523 4.558642 4.570983
#> [5,] 4.100917 4.077160 4.318253
#> [6,] 4.200000 4.148148 4.255850
#> [7,] 4.038532 4.370370 4.343214
#> [8,] 4.787156 4.529321 5.212168
#> [9,] 5.086239 4.978395 4.714509
#> [10,] 4.282569 4.314815 4.538222
#> [11,] 4.075229 4.675926 4.452418
#> [12,] 4.111927 4.557099 4.263651
#> [13,] 3.919266 4.501543 4.258970
#> [14,] 4.741284 4.388889 4.508580
#> [15,] 4.209174 4.970679 4.333853
#> [16,] 3.959633 4.240741 4.321373
#> CCTACACAGCCACGCT-b01 CCTCTGAAGCAACGGT-b01 CCTTCCCCACCTGGTG-b01
#> [1,] 4.371212 4.508065 4.439940
#> [2,] 4.647727 4.205645 4.018018
#> [3,] 4.494318 4.453629 4.043544
#> [4,] 4.352273 4.377016 4.118619
#> [5,] 4.691288 4.411290 4.710210
#> [6,] 4.465909 4.213710 4.426426
#> [7,] 4.172348 3.883065 4.243243
#> [8,] 5.287879 5.143145 5.097598
#> [9,] 4.401515 4.308468 4.277778
#> [10,] 3.660985 4.183468 4.208709
#> [11,] 4.064394 4.425403 4.040541
#> [12,] 4.854167 4.264113 4.325826
#> [13,] 4.244318 4.661290 4.542042
#> [14,] 4.535985 4.645161 4.704204
#> [15,] 4.153409 4.054435 4.078078
#> [16,] 3.920455 4.475806 4.731231
#> CCTTCGACATGTAGTC-b01 CGAACATAGCCGTCGT-b01 CGAACATTCTATCCCG-b01
#> [1,] 4.869739 4.808511 4.344037
#> [2,] 4.236473 4.771277 4.337920
#> [3,] 4.308617 4.049645 4.668196
#> [4,] 4.366733 4.129433 4.374618
#> [5,] 4.635271 4.242908 4.616208
#> [6,] 4.180361 4.028369 4.285933
#> [7,] 4.274549 4.017730 4.322630
#> [8,] 4.803607 4.728723 5.012232
#> [9,] 4.466934 4.056738 4.470948
#> [10,] 4.204409 4.622340 4.431193
#> [11,] 4.290581 4.374113 4.665138
#> [12,] 4.258517 4.845745 4.203364
#> [13,] 4.729459 4.296099 4.305810
#> [14,] 4.106212 4.239362 4.273700
#> [15,] 3.915832 3.867021 3.821101
#> [16,] 4.242485 4.432624 4.535168
#> CGACCTTTCCAATGGT-b01 CGAGAAGCACTGAAGG-b01 CGAGCCATCCCTTGCA-b01
#> [1,] 4.434462 3.983547 4.128788
#> [2,] 4.571429 4.014625 4.533333
#> [3,] 4.648012 4.062157 4.566667
#> [4,] 4.605302 4.175503 4.292424
#> [5,] 4.511046 4.137112 4.227273
#> [6,] 4.418262 4.987203 4.074242
#> [7,] 4.385862 3.946984 4.296970
#> [8,] 4.998527 4.647166 5.071212
#> [9,] 4.483063 4.659963 4.836364
#> [10,] 4.409426 4.009141 4.542424
#> [11,] 4.478645 3.875686 4.450000
#> [12,] 4.518409 4.557587 4.859091
#> [13,] 4.555228 3.945155 4.209091
#> [14,] 4.695140 4.961609 4.215152
#> [15,] 3.933726 3.720293 4.475758
#> [16,] 4.410898 4.638026 4.218182
#> CGATTGATCACATACG-b01 CGCTTCAAGTATGACA-b01 CGCTTCACAGATTGCT-b01
#> [1,] 4.6080 4.457961 4.302288
#> [2,] 4.1392 4.028623 4.243464
#> [3,] 4.3136 4.558140 4.202614
#> [4,] 4.2832 4.556351 3.995098
#> [5,] 4.0656 4.533095 4.537582
#> [6,] 4.0608 4.776386 4.357843
#> [7,] 4.3328 4.459750 4.612745
#> [8,] 4.7664 4.858676 5.166667
#> [9,] 4.3200 4.983900 4.460784
#> [10,] 4.2080 4.461538 4.080065
#> [11,] 4.4672 4.540250 4.083333
#> [12,] 4.4656 4.821109 4.630719
#> [13,] 4.4320 3.803220 4.333333
#> [14,] 4.2528 4.314848 4.413399
#> [15,] 3.9472 4.472272 4.093137
#> [16,] 4.3216 4.189624 3.720588
#> CGCTTCAGTGTAATGA-b01 CGGAGTCAGGGAACGG-b01 CGGAGTCTCGAACGGA-b01
#> [1,] 4.541818 4.303406 4.305118
#> [2,] 4.725455 4.199690 4.285433
#> [3,] 4.196364 4.351393 4.429134
#> [4,] 4.060000 4.369969 3.988189
#> [5,] 4.465455 4.360681 4.450787
#> [6,] 3.621818 4.182663 4.043307
#> [7,] 3.934545 4.278638 4.163386
#> [8,] 5.812727 5.006192 4.964567
#> [9,] 4.720000 4.605263 4.669291
#> [10,] 3.885455 4.068111 4.767717
#> [11,] 4.083636 4.417957 4.198819
#> [12,] 4.225455 4.111455 4.826772
#> [13,] 4.947273 4.535604 4.649606
#> [14,] 3.940000 3.975232 4.295276
#> [15,] 3.827273 3.885449 4.370079
#> [16,] 4.538182 4.363777 3.990157
#> CGTAGCGGTGGTACAG-b01 CGTGAGCAGACGCACA-b01 CGTGAGCTCCCTAATT-b01
#> [1,] 4.339130 4.408348 4.167870
#> [2,] 4.544348 4.228675 4.048736
#> [3,] 4.377391 4.459165 4.602888
#> [4,] 4.196522 4.557169 4.476534
#> [5,] 4.262609 4.880218 4.837545
#> [6,] 3.815652 4.029038 4.193141
#> [7,] 4.422609 4.422868 4.268953
#> [8,] 5.307826 5.264973 4.933213
#> [9,] 4.768696 4.778584 4.590253
#> [10,] 4.187826 4.508167 4.483755
#> [11,] 4.619130 4.250454 4.290614
#> [12,] 4.826087 4.747731 4.449458
#> [13,] 4.433043 4.676951 4.263538
#> [14,] 4.290435 4.500907 4.299639
#> [15,] 4.377391 4.201452 4.357401
#> [16,] 4.598261 4.165154 4.348375
#> CGTGTAACACCCATTC-b01 CGTGTCTAGGTGCTTT-b01 CGTGTCTTCTTCTGGC-b01
#> [1,] 4.648936 4.314371 4.079855
#> [2,] 3.817629 4.281437 4.301270
#> [3,] 4.145897 4.851796 4.511797
#> [4,] 4.253799 4.452096 4.551724
#> [5,] 4.911854 4.588323 4.493648
#> [6,] 3.826748 4.384731 4.609800
#> [7,] 4.522796 4.312874 4.139746
#> [8,] 4.639818 5.329341 5.205082
#> [9,] 4.196049 4.285928 4.573503
#> [10,] 4.193009 4.552395 4.495463
#> [11,] 4.044073 4.389222 4.308530
#> [12,] 4.203647 4.691617 4.381125
#> [13,] 4.302432 4.151198 4.279492
#> [14,] 4.477204 4.324850 4.949183
#> [15,] 4.194529 4.257485 4.058076
#> [16,] 3.990881 4.209581 4.562613
#> CTACGTCCAGTCTTCC-b01 CTCAGAATCCATGAAC-b01 CTCCTAGCATGTAAGA-b01
#> [1,] 4.314442 4.349823 4.397709
#> [2,] 4.460695 4.404594 4.260229
#> [3,] 4.385740 4.579505 4.430442
#> [4,] 4.288848 4.363958 4.700491
#> [5,] 4.510055 4.558304 4.415712
#> [6,] 4.513711 3.934629 4.320786
#> [7,] 4.182815 4.595406 4.509002
#> [8,] 4.700183 5.144876 4.934534
#> [9,] 4.215722 4.879859 4.243863
#> [10,] 4.389397 4.196113 4.638298
#> [11,] 4.528336 4.325088 4.472995
#> [12,] 4.776965 4.842756 4.487725
#> [13,] 4.486289 4.689046 4.263502
#> [14,] 3.979890 4.169611 4.184943
#> [15,] 4.480804 4.132509 4.404255
#> [16,] 4.513711 4.150177 4.297872
#> CTCGAGGGTATGAATG-b01 CTCGGGAAGTTCCACA-b01 CTCGGGATCGTCTGAA-b01
#> [1,] 4.456637 4.629921 4.173913
#> [2,] 4.415929 4.480315 4.086957
#> [3,] 4.410619 4.606299 4.338374
#> [4,] 4.394690 4.334646 4.068053
#> [5,] 4.196460 4.917323 4.867675
#> [6,] 4.081416 4.066929 4.030246
#> [7,] 4.143363 3.866142 4.661626
#> [8,] 4.994690 5.346457 4.353497
#> [9,] 5.311504 4.411417 4.156900
#> [10,] 4.476106 4.147638 4.217391
#> [11,] 4.284956 4.297244 4.308129
#> [12,] 4.541593 4.322835 4.172023
#> [13,] 4.161062 4.917323 4.085066
#> [14,] 4.440708 4.118110 4.542533
#> [15,] 4.357522 3.844488 3.850662
#> [16,] 4.307965 4.220472 3.848771
#> CTCTAATAGGGTATCG-b01 CTCTACGGTCCAAGTT-b01 CTGATAGGTTAAGGGC-b01
#> [1,] 3.856459 4.352574 4.669725
#> [2,] 4.784689 4.087363 4.220183
#> [3,] 4.352472 4.508580 4.044343
#> [4,] 4.167464 4.379095 3.585627
#> [5,] 4.065391 4.552262 5.258410
#> [6,] 4.127592 4.480499 3.949541
#> [7,] 4.177033 4.124805 3.654434
#> [8,] 4.889952 5.042122 5.588685
#> [9,] 5.060606 4.716069 4.458716
#> [10,] 4.805423 4.358814 3.750765
#> [11,] 4.288676 4.531981 4.249235
#> [12,] 4.543860 4.363495 4.032110
#> [13,] 4.366826 4.541342 5.685015
#> [14,] 4.113238 4.464899 4.038226
#> [15,] 4.885167 4.021841 3.764526
#> [16,] 4.036683 4.170047 4.204893
#> CTGATCCAGATCTGAA-b01 CTGATCCGTATATGGA-b01 CTGCTGTAGGGAACGG-b01
#> [1,] 4.283019 4.850719 4.588737
#> [2,] 4.213353 4.553957 3.762799
#> [3,] 4.314949 4.253597 4.269625
#> [4,] 4.786647 4.377698 4.286689
#> [5,] 4.474601 4.535971 4.346416
#> [6,] 4.419448 3.892086 4.199659
#> [7,] 4.317852 4.174460 4.307167
#> [8,] 5.359942 4.875899 5.071672
#> [9,] 4.737300 4.564748 4.757679
#> [10,] 4.589260 4.449640 4.098976
#> [11,] 4.227866 4.681655 4.276451
#> [12,] 4.329463 4.627698 4.757679
#> [13,] 4.442671 4.780576 4.597270
#> [14,] 4.281567 4.377698 4.343003
#> [15,] 4.445573 4.257194 4.124573
#> [16,] 4.059507 4.690647 4.191126
#> CTGGTCTTCCTAGTGA-b01 CTTAACTGTTCAGGCC-b01 CTTACCGAGCCAGGAT-b01
#> [1,] 4.382609 3.972222 4.509061
#> [2,] 4.309565 4.555556 4.629325
#> [3,] 4.641739 3.970679 4.317957
#> [4,] 4.205217 4.535494 4.695222
#> [5,] 4.549565 4.283951 4.453048
#> [6,] 4.286957 4.067901 4.365733
#> [7,] 4.408696 4.535494 4.403624
#> [8,] 5.060870 5.199074 4.998353
#> [9,] 5.299130 4.604938 4.090610
#> [10,] 4.431304 4.350309 4.721582
#> [11,] 4.373913 4.341049 4.232290
#> [12,] 4.773913 3.993827 4.107084
#> [13,] 4.441739 4.660494 4.751236
#> [14,] 4.540870 4.486111 4.296540
#> [15,] 4.429565 3.955247 4.039539
#> [16,] 4.666087 4.216049 4.199341
#> CTTACCGCATTCCTCG-b01 CTTTGCGCACAAGACG-b01 GAAACTCCACGCCAGT-b01
#> [1,] 4.248921 4.129338 4.172821
#> [2,] 4.010072 4.145110 4.162482
#> [3,] 4.457554 4.441640 4.419498
#> [4,] 4.333813 4.591483 4.277696
#> [5,] 4.805755 4.780757 4.376662
#> [6,] 4.614388 4.235016 4.121123
#> [7,] 3.956835 4.348580 4.248154
#> [8,] 5.109353 4.935331 4.970458
#> [9,] 4.466187 4.697161 3.933530
#> [10,] 4.382734 4.018927 4.063516
#> [11,] 4.351079 4.287066 4.196455
#> [12,] 4.463309 4.593060 4.366322
#> [13,] 4.541007 4.089905 4.827179
#> [14,] 4.066187 4.337539 4.366322
#> [15,] 4.458993 3.919558 4.435746
#> [16,] 4.307914 4.365931 4.208272
#> GAACATCTCGTAGGTT-b01 GACACGCCAACGATCT-b01 GACCTGGGTCCGAACC-b01
#> [1,] 4.486207 4.099426 4.157321
#> [2,] 4.377586 4.674952 3.746106
#> [3,] 4.487931 4.512428 3.884735
#> [4,] 4.563793 4.560229 3.906542
#> [5,] 4.113793 4.625239 3.780374
#> [6,] 3.984483 4.235182 5.197819
#> [7,] 4.010345 4.357553 4.119938
#> [8,] 4.987931 4.925430 4.489097
#> [9,] 5.067241 4.627151 4.401869
#> [10,] 4.224138 4.384321 4.010903
#> [11,] 4.031034 4.602294 4.057632
#> [12,] 4.296552 4.573614 4.068536
#> [13,] 4.136207 4.177820 3.922118
#> [14,] 4.441379 4.516252 4.962617
#> [15,] 4.193103 4.166348 4.193146
#> [16,] 4.050000 4.653920 4.805296
#> GACGCGTCACCGAATT-b01 GACGTGCGTGTTGAGG-b01 GACTAACGTCTAGAGG-b01
#> [1,] 4.200730 4.703901 4.385307
#> [2,] 4.180657 4.180851 4.352324
#> [3,] 4.277372 4.221631 4.307346
#> [4,] 3.912409 4.019504 4.260870
#> [5,] 4.273723 4.395390 4.286357
#> [6,] 4.500000 4.705674 4.451274
#> [7,] 4.125912 4.166667 4.193403
#> [8,] 5.297445 4.710993 4.824588
#> [9,] 4.479927 4.462766 4.451274
#> [10,] 4.332117 4.214539 4.439280
#> [11,] 4.125912 3.996454 4.395802
#> [12,] 4.673358 4.705674 4.317841
#> [13,] 4.620438 4.180851 4.589205
#> [14,] 4.202555 4.948582 4.163418
#> [15,] 4.500000 4.317376 4.203898
#> [16,] 4.229927 5.092199 4.322339
#> GACTAACGTGCCTGTG-b01 GACTACATCACTGGGC-b01 GAGCAGACAATCTGCA-b01
#> [1,] 4.528674 4.150000 4.347032
#> [2,] 4.310036 3.953846 4.178082
#> [3,] 4.146953 3.978846 4.607306
#> [4,] 4.603943 3.892308 4.771689
#> [5,] 4.670251 4.013462 4.794521
#> [6,] 4.476703 5.115385 3.946728
#> [7,] 4.302867 4.534615 4.345510
#> [8,] 5.120072 4.871154 4.783866
#> [9,] 4.308244 4.442308 4.543379
#> [10,] 3.960573 4.186538 4.089802
#> [11,] 4.408602 4.384615 4.219178
#> [12,] 4.860215 4.034615 4.016743
#> [13,] 4.105735 4.067308 4.455099
#> [14,] 4.528674 4.944231 4.347032
#> [15,] 4.179211 4.253846 4.071537
#> [16,] 4.075269 4.625000 4.016743
#> GAGCAGACAGGCTGAA-b01 GAGGTGAGTAGAGCTG-b01 GAGTCCGGTAATCGTC-b01
#> [1,] 4.395731 3.914186 3.940631
#> [2,] 4.178982 4.297723 4.220779
#> [3,] 4.310345 4.357268 4.484230
#> [4,] 3.980296 4.264448 4.317254
#> [5,] 4.889984 4.721541 4.031540
#> [6,] 3.817734 4.042032 3.946197
#> [7,] 4.727422 4.259194 4.204082
#> [8,] 4.584565 4.756567 4.992579
#> [9,] 3.926108 4.502627 4.588126
#> [10,] 3.926108 3.901926 4.001855
#> [11,] 4.034483 4.399299 4.717996
#> [12,] 4.316913 4.502627 4.098330
#> [13,] 4.155993 4.056042 4.536178
#> [14,] 4.353038 4.492119 4.491651
#> [15,] 4.041051 4.110333 4.163265
#> [16,] 4.208539 4.373030 4.118738
#> GATCGCGTCTGCTGCT-b01 GATCTAGGTATGGTTC-b01 GATCTAGTCCACGTGG-b01
#> [1,] 4.830861 4.381329 4.359155
#> [2,] 4.274481 4.185127 4.082746
#> [3,] 4.436202 4.422468 4.616197
#> [4,] 4.181009 4.479430 4.536972
#> [5,] 4.839763 4.419304 4.566901
#> [6,] 4.038576 4.302215 4.080986
#> [7,] 4.308605 4.162975 4.213028
#> [8,] 4.908012 4.840190 4.698944
#> [9,] 4.295252 4.254747 4.417254
#> [10,] 4.145401 4.294304 4.269366
#> [11,] 4.025223 4.169304 4.536972
#> [12,] 4.038576 4.232595 4.477113
#> [13,] 4.500000 4.300633 4.441901
#> [14,] 4.292285 4.238924 3.906690
#> [15,] 4.124629 4.191456 4.147887
#> [16,] 4.013353 3.825949 4.485915
#> GATGAAATCCGAAGAG-b01 GATGAGGAGGTTCCTA-b01 GATGAGGCATTGGTAC-b01
#> [1,] 4.561832 4.228571 4.377152
#> [2,] 4.387786 3.944643 4.577465
#> [3,] 4.494656 4.314286 4.320814
#> [4,] 4.442748 4.378571 4.208138
#> [5,] 4.517557 4.394643 4.485133
#> [6,] 4.170992 4.237500 4.275430
#> [7,] 4.195420 4.046429 4.269171
#> [8,] 4.952672 5.121429 4.788732
#> [9,] 4.348092 4.467857 4.264476
#> [10,] 4.375573 4.075000 4.181534
#> [11,] 4.291603 4.164286 4.442879
#> [12,] 4.259542 4.644643 4.311424
#> [13,] 4.407634 4.748214 4.741784
#> [14,] 4.676336 4.450000 4.384977
#> [15,] 4.285496 3.980357 4.169014
#> [16,] 4.077863 4.319643 4.508607
#> GCACTCTGTGGGTCAA-b01 GCAGTTAGTCGAACAG-b01 GCATGATTCGCTTGTC-b01
#> [1,] 4.474860 4.085484 4.220513
#> [2,] 4.441341 4.143548 4.343590
#> [3,] 4.065177 3.893548 4.078632
#> [4,] 4.445065 4.269355 4.184615
#> [5,] 4.588454 4.435484 4.418803
#> [6,] 4.547486 4.730645 4.280342
#> [7,] 4.040968 4.453226 4.576068
#> [8,] 4.776536 5.050000 4.760684
#> [9,] 4.433892 3.988710 4.480342
#> [10,] 4.258845 4.720968 4.167521
#> [11,] 4.234637 4.211290 4.536752
#> [12,] 4.400372 4.085484 4.514530
#> [13,] 4.748603 4.322581 4.499145
#> [14,] 4.607076 4.950000 4.294017
#> [15,] 4.039106 4.153226 4.259829
#> [16,] 5.178771 4.533871 4.266667
#> GCCAAATGTACCAGTT-b01 GCGAGAAGTCGGCATC-b01 GCGAGAAGTGAGGCTA-b01
#> [1,] 4.443697 4.062500 4.868979
#> [2,] 4.280672 4.533203 4.489403
#> [3,] 4.228571 4.750000 4.562620
#> [4,] 4.539496 4.333984 4.710983
#> [5,] 4.189916 4.449219 4.678227
#> [6,] 4.137815 4.324219 3.828516
#> [7,] 4.408403 4.136719 4.154143
#> [8,] 5.341176 4.634766 4.815029
#> [9,] 4.842017 4.156250 4.483622
#> [10,] 4.315966 4.242188 4.231214
#> [11,] 4.546218 4.544922 4.398844
#> [12,] 4.262185 4.595703 4.260116
#> [13,] 4.107563 4.445312 4.262042
#> [14,] 4.443697 4.505859 4.221580
#> [15,] 4.569748 4.332031 3.691715
#> [16,] 4.393277 4.699219 4.269750
#> GCGAGAAGTTAAGGGC-b01 GCGCAACAGTTGTAGA-b01 GCGCAGTCAGTATGCT-b01
#> [1,] 4.411335 4.511304 4.288201
#> [2,] 4.254113 4.340870 4.562863
#> [3,] 4.190128 4.655652 4.193424
#> [4,] 4.334552 4.090435 4.230174
#> [5,] 4.127971 4.671304 4.705996
#> [6,] 4.126143 3.880000 4.280464
#> [7,] 4.369287 4.540870 4.539652
#> [8,] 4.954296 5.288696 4.553191
#> [9,] 4.755027 4.497391 4.413926
#> [10,] 4.051188 4.316522 4.297872
#> [11,] 4.407678 4.598261 4.218569
#> [12,] 4.650823 4.526957 4.264990
#> [13,] 4.468007 4.191304 4.077369
#> [14,] 4.276051 4.149565 4.740812
#> [15,] 4.480804 4.417391 4.032882
#> [16,] 4.429616 4.462609 4.058027
#> GCGCGATAGGACATTA-b01 GCTGCAGAGAGGACGG-b01 GCTGCAGAGATGTGGC-b01
#> [1,] 4.530100 4.598976 4.109477
#> [2,] 4.290970 4.022184 4.065359
#> [3,] 4.279264 3.786689 4.034314
#> [4,] 4.496656 3.622867 4.423203
#> [5,] 4.346154 4.614334 4.344771
#> [6,] 4.401338 3.805461 4.736928
#> [7,] 4.909699 3.993174 4.290850
#> [8,] 4.675585 5.078498 5.017974
#> [9,] 4.324415 5.075085 4.166667
#> [10,] 4.212375 3.931741 4.107843
#> [11,] 4.173913 4.052901 4.253268
#> [12,] 4.550167 4.479522 4.053922
#> [13,] 4.831104 4.829352 4.132353
#> [14,] 4.160535 4.245734 4.959150
#> [15,] 4.508361 3.909556 3.908497
#> [16,] 4.371237 4.402730 4.764706
#> GCTGCTTAGGCATTGG-b01 GCTGCTTCAAATCCGT-b01 GGAACTTGTAATCGTC-b01
#> [1,] 4.363118 4.242188 4.302135
#> [2,] 4.395437 4.279297 4.192118
#> [3,] 4.357414 4.630859 4.236453
#> [4,] 4.534221 4.279297 4.293924
#> [5,] 4.173004 4.318359 4.490969
#> [6,] 4.357414 3.718750 4.747126
#> [7,] 3.998099 4.353516 4.683087
#> [8,] 4.693916 4.820312 4.975369
#> [9,] 4.904943 4.371094 4.389163
#> [10,] 4.543726 3.742188 4.231527
#> [11,] 4.309886 4.146484 4.220033
#> [12,] 4.313688 4.501953 4.377668
#> [13,] 4.096958 4.490234 4.154351
#> [14,] 4.733840 4.392578 5.044335
#> [15,] 4.526616 4.246094 3.917898
#> [16,] 4.209125 4.212891 4.779967
#> GGACAGAAGATAGTCA-b01 GGACGTCTCGCGATCG-b01 GGATTACTCCCGACTT-b01
#> [1,] 4.252129 4.662675 4.149425
#> [2,] 4.747871 4.562874 4.349754
#> [3,] 4.045997 4.481038 4.210181
#> [4,] 4.018739 4.327345 4.642036
#> [5,] 4.439523 4.542914 4.591133
#> [6,] 4.514480 3.658683 3.942529
#> [7,] 4.281090 4.499002 4.495895
#> [8,] 4.596252 4.942116 4.551724
#> [9,] 4.630324 4.293413 4.356322
#> [10,] 4.209540 4.143713 4.111658
#> [11,] 4.628620 4.087824 4.492611
#> [12,] 5.042589 4.514970 4.454844
#> [13,] 4.001704 4.526946 4.545156
#> [14,] 4.345826 4.245509 4.302135
#> [15,] 3.909710 4.275449 4.264368
#> [16,] 3.952300 4.371257 4.461412
#> GGCTGGTTCCGGCACA-b01 GGGCACTCAATCCGAT-b01 GGGCACTCAGGACCCT-b01
#> [1,] 4.112342 4.262443 4.330020
#> [2,] 3.892405 4.206637 4.117296
#> [3,] 4.033228 4.046757 4.236581
#> [4,] 4.397152 4.054299 4.081511
#> [5,] 4.488924 4.343891 4.530815
#> [6,] 3.950949 4.674208 4.011928
#> [7,] 3.981013 4.128205 4.787276
#> [8,] 5.219937 4.800905 4.888668
#> [9,] 4.944620 4.324284 4.791252
#> [10,] 4.022152 4.125189 4.099404
#> [11,] 4.406646 4.254902 4.109344
#> [12,] 4.495253 3.883861 4.264414
#> [13,] 4.637658 4.114630 4.371769
#> [14,] 4.500000 4.573152 4.318091
#> [15,] 4.268987 4.137255 4.341948
#> [16,] 4.229430 4.521870 4.725646
#> GGGCATCGTGCACGAA-b01 GGGTCTGAGGTGCTTT-b01 GGGTTGCGTAGAGTGC-b01
#> [1,] 4.605697 4.641075 4.323099
#> [2,] 4.575712 4.282150 4.209064
#> [3,] 4.076462 4.099808 4.609649
#> [4,] 4.415292 4.205374 4.385965
#> [5,] 4.601199 4.485605 4.482456
#> [6,] 4.361319 4.191939 3.997076
#> [7,] 4.115442 4.061420 4.340643
#> [8,] 5.329835 4.875240 4.618421
#> [9,] 4.829085 4.802303 4.288012
#> [10,] 4.296852 4.128599 4.301170
#> [11,] 4.383808 4.126679 4.399123
#> [12,] 4.455772 4.026871 4.258772
#> [13,] 4.334333 4.520154 4.549708
#> [14,] 4.349325 4.531670 4.311404
#> [15,] 3.944528 3.765835 4.269006
#> [16,] 4.356822 4.472169 4.314327
#> GTACTTTGTCATTAGC-b01 GTCACAACATTGGCGC-b01 GTCACGGCATGGTCTA-b01
#> [1,] 4.232812 4.195122 4.064562
#> [2,] 4.065625 4.264540 4.512195
#> [3,] 4.207812 4.363977 4.253945
#> [4,] 4.385937 4.303940 4.111908
#> [5,] 4.551562 4.622889 3.621234
#> [6,] 4.854687 3.998124 3.789096
#> [7,] 4.132812 4.011257 4.172166
#> [8,] 4.984375 4.844278 5.345768
#> [9,] 4.128125 4.454034 5.235294
#> [10,] 4.339062 4.232645 4.456241
#> [11,] 4.204687 4.452158 4.411765
#> [12,] 4.515625 4.418386 4.302726
#> [13,] 4.137500 4.545966 4.275466
#> [14,] 4.631250 4.424015 4.417504
#> [15,] 4.148437 3.814259 4.852224
#> [16,] 4.532812 4.626642 4.192253
#> GTCCTCACAGTCCTTC-b01 GTCTTCGCAACTGCGC-b01 GTGCATAAGGTGCACA-b01
#> [1,] 4.423077 4.187500 4.454054
#> [2,] 4.472028 4.522321 4.446847
#> [3,] 4.417832 4.627976 4.365766
#> [4,] 4.519231 4.500000 4.209009
#> [5,] 4.669580 4.394345 4.648649
#> [6,] 3.790210 4.308036 3.922523
#> [7,] 4.377622 4.172619 4.189189
#> [8,] 4.916084 5.172619 5.059459
#> [9,] 4.837413 4.748512 4.237838
#> [10,] 4.124126 4.575893 4.052252
#> [11,] 4.248252 4.534226 4.376577
#> [12,] 4.251748 4.211310 4.219820
#> [13,] 4.431818 4.501488 4.313514
#> [14,] 4.886364 4.688988 3.890090
#> [15,] 4.262238 4.308036 3.830631
#> [16,] 4.129371 4.275298 4.423423
#> GTGCTTCGTGTGACGA-b01 GTGCTTCTCCTTAATC-b01 GTGGGTCCACAGGCCT-b01
#> [1,] 4.092409 4.088409 4.465190
#> [2,] 4.049505 4.467583 4.115506
#> [3,] 3.955446 4.398821 4.493671
#> [4,] 4.572607 4.045187 4.680380
#> [5,] 4.466997 4.644401 4.224684
#> [6,] 3.915842 4.145383 4.153481
#> [7,] 4.759076 4.432220 4.210443
#> [8,] 4.501650 4.724951 5.155063
#> [9,] 4.735974 4.713163 5.196203
#> [10,] 4.359736 4.559921 4.158228
#> [11,] 4.429043 4.278978 4.234177
#> [12,] 4.257426 4.538310 4.363924
#> [13,] 4.740924 4.614931 4.177215
#> [14,] 3.907591 4.277014 4.561709
#> [15,] 4.422442 4.045187 4.302215
#> [16,] 4.311881 4.442043 4.224684
#> GTTAAGCGTTAAGGGC-b01 GTTCGGGAGATCCGAG-b01 GTTCTCGAGAGGTAGA-b01
#> [1,] 4.362096 4.406100 4.503058
#> [2,] 4.201849 4.268058 4.181957
#> [3,] 3.918336 4.377207 4.224771
#> [4,] 4.070878 4.446228 4.432722
#> [5,] 4.795069 4.608347 4.200306
#> [6,] 4.342065 3.878010 4.305810
#> [7,] 4.388290 4.022472 4.347095
#> [8,] 5.152542 4.523274 4.831804
#> [9,] 4.537750 4.452648 4.585627
#> [10,] 4.127889 4.069021 4.162080
#> [11,] 4.432974 4.412520 4.201835
#> [12,] 4.112481 4.213483 4.181957
#> [13,] 4.309707 4.515249 4.241590
#> [14,] 4.295840 4.130016 4.406728
#> [15,] 4.161787 3.805778 4.093272
#> [16,] 4.158706 4.603531 4.292049
#> GTTCTCGAGTGGGTTG-b01 TAAACCGAGAAACGAG-b01 TACACGAGTACAAGTA-b01
#> [1,] 4.534985 4.333981 4.504456
#> [2,] 4.298834 4.097087 4.406417
#> [3,] 4.616618 4.601942 4.595365
#> [4,] 4.510204 4.761165 4.688057
#> [5,] 4.604956 5.050485 4.720143
#> [6,] 4.399417 4.040777 4.588235
#> [7,] 4.551020 4.238835 4.614973
#> [8,] 5.234694 5.062136 5.235294
#> [9,] 4.543732 5.192233 4.525847
#> [10,] 4.559767 4.281553 4.283422
#> [11,] 4.336735 4.473786 4.761141
#> [12,] 4.731778 4.485437 4.614973
#> [13,] 4.304665 4.638835 4.288770
#> [14,] 4.004373 4.203883 4.422460
#> [15,] 4.134111 3.941748 4.210339
#> [16,] 4.118076 4.384466 4.028520
#> TACGGTATCTTCCTTC-b01 TACTCATAGATACACA-b01 TACTCGCCACGTAAGG-b01
#> [1,] 5.084479 4.316637 4.523308
#> [2,] 4.021611 4.164580 4.267669
#> [3,] 4.003929 4.211091 4.436090
#> [4,] 3.954813 4.252236 4.643609
#> [5,] 5.023576 4.491950 4.123308
#> [6,] 3.986248 4.438283 4.384962
#> [7,] 3.620825 4.472272 4.481203
#> [8,] 5.143418 4.601073 5.082707
#> [9,] 4.878193 4.391771 4.577444
#> [10,] 4.123772 4.118068 4.463158
#> [11,] 3.703340 4.316637 4.354887
#> [12,] 4.322200 4.216458 4.336842
#> [13,] 5.424361 4.228980 4.526316
#> [14,] 3.614931 4.499106 4.437594
#> [15,] 3.907662 4.309481 4.009023
#> [16,] 3.948919 4.223614 4.281203
#> TAGTGGTGTGTTAAGA-b01 TATGCCCCAGGTCGTC-b01 TCAACGATCCTATGTT-b01
#> [1,] 4.511883 4.187779 4.341021
#> [2,] 4.307130 4.216095 4.276771
#> [3,] 4.323583 4.496274 4.457990
#> [4,] 4.268739 4.862891 4.367381
#> [5,] 4.314442 4.901639 4.416804
#> [6,] 4.385740 4.186289 4.377265
#> [7,] 4.358318 4.369598 4.377265
#> [8,] 4.795247 4.599106 4.723229
#> [9,] 4.416819 4.858420 4.624382
#> [10,] 3.976234 4.591654 4.579901
#> [11,] 4.343693 4.262295 4.490939
#> [12,] 4.393053 4.616990 4.416804
#> [13,] 4.444241 4.028316 4.660626
#> [14,] 4.060329 4.374069 4.182867
#> [15,] 4.133455 4.865872 4.294893
#> [16,] 4.533821 4.314456 4.517298
#> TCAACGATCTAACCGA-b01 TCAATCTCAGGGTTAG-b01 TCAGCAAAGCTAACTC-b01
#> [1,] 4.284965 4.398333 4.625436
#> [2,] 4.108392 4.393333 4.179443
#> [3,] 4.510490 3.918333 4.266551
#> [4,] 4.417832 4.345000 4.137631
#> [5,] 4.459790 4.656667 4.602787
#> [6,] 4.342657 4.136667 4.496516
#> [7,] 4.218531 4.411667 4.351916
#> [8,] 4.667832 5.081667 4.879791
#> [9,] 4.611888 4.673333 4.684669
#> [10,] 4.253497 4.281667 4.500000
#> [11,] 4.375874 4.440000 4.560976
#> [12,] 4.578671 4.696667 4.479094
#> [13,] 4.723776 4.825000 4.459930
#> [14,] 4.197552 4.516667 4.301394
#> [15,] 4.486014 4.231667 4.163763
#> [16,] 4.374126 4.591667 4.459930
#> TCAGCTCCAGACAAAT-b01 TCAGGATGTGGACGAT-b01 TCATTACGTCCAGTAT-b01
#> [1,] 4.506261 4.668 4.246978
#> [2,] 4.642218 3.930 4.074266
#> [3,] 3.971377 4.282 4.457686
#> [4,] 4.769231 4.094 4.170984
#> [5,] 4.706619 5.002 4.371330
#> [6,] 4.157424 4.242 4.157168
#> [7,] 4.264758 4.602 4.386874
#> [8,] 5.268336 4.560 4.704663
#> [9,] 4.275492 5.260 4.499136
#> [10,] 3.985689 4.148 4.447323
#> [11,] 4.230769 4.266 4.186528
#> [12,] 4.742397 4.878 4.464594
#> [13,] 4.497317 4.854 4.374784
#> [14,] 4.178891 4.212 4.195164
#> [15,] 4.588551 4.218 4.721934
#> [16,] 4.336315 4.774 4.511226
#> TCCACACCACACAGAG-b01 TCCACACGTGCAACGA-b01 TCGGTAAGTCATCGGC-b01
#> [1,] 4.459150 4.366197 4.379645
#> [2,] 4.238562 4.356808 4.315024
#> [3,] 4.699346 4.643192 4.214863
#> [4,] 4.235294 4.403756 4.360258
#> [5,] 4.446078 4.392801 4.515347
#> [6,] 4.725490 4.347418 4.368336
#> [7,] 4.431373 3.882629 4.437803
#> [8,] 5.071895 5.228482 4.885299
#> [9,] 4.803922 4.657277 4.331179
#> [10,] 4.300654 3.906103 4.247173
#> [11,] 4.197712 4.198748 4.381260
#> [12,] 4.398693 4.780908 4.255250
#> [13,] 4.429739 4.500782 4.392569
#> [14,] 4.433007 4.120501 4.164782
#> [15,] 4.047386 4.508607 4.059774
#> [16,] 4.114379 4.555556 4.344103
#> TCGTAGATCATCGGAT-b01 TCTTCGGGTTCCTCCA-b01 TCTTTCCGTAGCCTCG-b01
#> [1,] 4.208103 4.174803 4.136986
#> [2,] 4.174954 4.388976 4.242009
#> [3,] 3.935543 4.505512 4.579909
#> [4,] 4.018416 4.645669 4.205479
#> [5,] 4.515654 4.280315 4.706240
#> [6,] 4.372007 4.307087 4.260274
#> [7,] 4.270718 4.392126 4.056317
#> [8,] 4.871087 5.099213 5.088280
#> [9,] 4.445672 4.439370 4.719939
#> [10,] 4.057090 4.124409 4.280061
#> [11,] 4.257827 4.365354 4.480974
#> [12,] 4.445672 4.807874 4.687976
#> [13,] 4.178637 4.020472 4.560122
#> [14,] 4.453039 4.451969 4.348554
#> [15,] 4.093923 4.319685 4.240487
#> [16,] 4.521179 4.061417 4.356164
#> TCTTTCCGTATAGTAG-b01 TGAGCCGTCTTCGAGA-b01 TGAGGGATCATGGTCA-b01
#> [1,] 4.645221 4.512573 4.548780
#> [2,] 4.159926 4.205029 4.204268
#> [3,] 4.341912 4.334623 4.490854
#> [4,] 4.718750 4.065764 4.329268
#> [5,] 4.924632 4.437137 4.294207
#> [6,] 4.514706 4.042553 3.890244
#> [7,] 4.810662 4.257253 4.024390
#> [8,] 5.204044 5.063830 4.826220
#> [9,] 4.630515 4.510638 5.003049
#> [10,] 4.398897 4.193424 4.454268
#> [11,] 4.211397 4.270793 4.554878
#> [12,] 4.533088 4.253385 4.535061
#> [13,] 4.430147 4.735010 4.528963
#> [14,] 4.075368 4.226306 4.332317
#> [15,] 4.325368 3.791103 4.128049
#> [16,] 4.134191 4.321083 4.387195
#> TGATTTCAGACTAAGT-b01 TGCACCTTCGTGGTCG-b01 TGCGCAGAGGCCATAG-b01
#> [1,] 4.299353 4.358006 4.064145
#> [2,] 4.665049 4.276435 4.481908
#> [3,] 3.974110 4.206949 4.376645
#> [4,] 4.197411 4.240181 4.807566
#> [5,] 4.673139 4.406344 4.263158
#> [6,] 4.304207 4.663142 4.296053
#> [7,] 4.186084 4.358006 4.210526
#> [8,] 4.838188 4.968278 4.799342
#> [9,] 4.255663 4.364048 5.152961
#> [10,] 4.635922 4.483384 4.337171
#> [11,] 4.166667 4.099698 4.208882
#> [12,] 4.542071 4.790030 4.273026
#> [13,] 4.464401 4.586103 4.199013
#> [14,] 4.564725 4.364048 4.402961
#> [15,] 4.022654 4.234139 4.024671
#> [16,] 4.114887 4.552870 4.646382
#> TGCGCAGTCAAGGCTT-b01 TGCGGGTCATGTTCCC-b01 TGGCGCACATCCTAGA-b01
#> [1,] 4.333887 4.552727 4.431985
#> [2,] 4.360465 3.929091 4.362132
#> [3,] 4.712625 4.267273 4.393382
#> [4,] 4.443522 4.143636 4.487132
#> [5,] 4.397010 4.330909 4.169118
#> [6,] 4.187708 4.180000 4.286765
#> [7,] 4.294020 4.307273 4.255515
#> [8,] 4.551495 5.303636 4.909926
#> [9,] 4.481728 4.450909 4.454044
#> [10,] 4.224252 4.078182 4.255515
#> [11,] 4.124585 4.081818 4.068015
#> [12,] 4.358804 4.163636 4.071691
#> [13,] 4.737542 4.827273 4.261029
#> [14,] 4.146179 3.863636 4.183824
#> [15,] 4.184385 4.369091 4.259191
#> [16,] 4.310631 4.483636 4.321691
#> TGGCTGGGTGAGGCTA-b01 TGGCTGGTCTGCTGTC-b01 TGGGCGTGTCAAAGAT-b01
#> [1,] 4.477927 4.298148 4.391442
#> [2,] 4.428023 4.735185 4.171157
#> [3,] 4.368522 4.631481 4.270998
#> [4,] 4.683301 4.572222 4.307448
#> [5,] 4.301344 4.207407 4.516640
#> [6,] 4.318618 4.342593 3.873217
#> [7,] 4.381958 4.131481 4.082409
#> [8,] 4.646833 5.075926 5.494453
#> [9,] 4.431862 4.887037 4.351823
#> [10,] 4.558541 4.375926 4.334390
#> [11,] 4.474088 4.455556 4.117274
#> [12,] 4.380038 4.800000 4.315372
#> [13,] 4.243762 4.314815 4.515055
#> [14,] 4.143954 4.575926 4.269414
#> [15,] 3.857965 4.244444 4.440571
#> [16,] 4.364683 4.448148 4.358162
#> TGTCCCAGTTAAGAAC-b01 TTCGAAGCATTGGGCC-b01 TTCTCAAGTCAGCTAT-b01
#> [1,] 4.191870 4.768657 4.517241
#> [2,] 4.370732 4.289179 4.159004
#> [3,] 4.312195 4.197761 4.145594
#> [4,] 4.141463 4.380597 4.124521
#> [5,] 4.400000 4.376866 4.005747
#> [6,] 4.639024 4.246269 4.128352
#> [7,] 4.445528 3.945896 4.300766
#> [8,] 4.697561 4.873134 5.136015
#> [9,] 4.315447 4.600746 4.362069
#> [10,] 4.282927 4.419776 4.187739
#> [11,] 4.551220 4.083955 4.153257
#> [12,] 4.092683 4.630597 4.103448
#> [13,] 4.456911 4.751866 4.295019
#> [14,] 4.448780 4.220149 4.329502
#> [15,] 4.008130 3.912313 4.206897
#> [16,] 4.591870 4.156716 4.480843
#> TTGGAACAGTATCTCG-b01 TTGTAGGCAAGCTGAG-b01 TTGTAGGGTTACTGAC-b01
#> [1,] 4.416923 4.247604 4.244012
#> [2,] 4.143077 4.148562 4.437126
#> [3,] 4.246154 4.062300 4.176647
#> [4,] 4.727692 4.226837 4.422156
#> [5,] 4.296923 4.495208 4.534431
#> [6,] 3.821538 4.116613 3.992515
#> [7,] 3.983077 4.110224 4.790419
#> [8,] 4.918462 5.063898 4.791916
#> [9,] 4.576923 4.722045 4.453593
#> [10,] 4.481538 3.758786 4.082335
#> [11,] 4.396923 4.506390 4.559880
#> [12,] 4.621538 4.629393 4.703593
#> [13,] 4.236923 4.551118 4.577844
#> [14,] 4.216923 4.351438 3.979042
#> [15,] 4.118462 4.226837 4.544910
#> [16,] 4.173846 4.321086 4.502994
#> AACACGTGTACAAGTA-b02 AAGGCAGGTTCACGGC-b02 ACACCCTGTATTCTCT-b02
#> [1,] 4.295950 3.982558 4.437086
#> [2,] 4.160436 4.259690 4.273179
#> [3,] 4.573209 4.079457 3.912252
#> [4,] 4.462617 4.032946 4.463576
#> [5,] 4.411215 3.846899 5.074503
#> [6,] 4.602804 4.633721 4.241722
#> [7,] 4.222741 4.224806 3.991722
#> [8,] 5.433022 4.926357 5.430464
#> [9,] 4.306854 4.651163 4.918874
#> [10,] 4.249221 4.191860 4.491722
#> [11,] 3.925234 4.019380 4.354305
#> [12,] 5.129283 4.180233 4.390728
#> [13,] 4.197819 3.963178 3.975166
#> [14,] 4.289720 4.831395 4.753311
#> [15,] 4.091900 4.110465 4.153974
#> [16,] 4.247664 4.825581 4.508278
#> ACATACGCATGGGAAC-b02 ACATCAGGTAAGTTCC-b02 ACATGGTCAAGTTAAG-b02
#> [1,] 3.934046 4.305800 4.259259
#> [2,] 4.397504 4.103691 4.398589
#> [3,] 4.260250 4.072056 4.410935
#> [4,] 4.285205 3.905097 4.359788
#> [5,] 3.980392 4.161687 4.343915
#> [6,] 4.226381 4.813708 4.024691
#> [7,] 4.199643 3.989455 4.400353
#> [8,] 5.497326 5.202109 5.292769
#> [9,] 4.593583 4.803163 4.119929
#> [10,] 4.368984 3.748682 4.282187
#> [11,] 3.967914 3.822496 4.158730
#> [12,] 4.796791 4.080844 4.396825
#> [13,] 4.541889 4.019332 4.366843
#> [14,] 4.973262 4.933216 4.252205
#> [15,] 4.347594 4.066784 4.241623
#> [16,] 4.183601 5.198594 4.504409
#> ACATGGTGTTATGCGT-b02 ACGCCGAAGAGTCTGG-b02 ACGTCAACAATCTGCA-b02
#> [1,] 4.168126 4.506569 4.117005
#> [2,] 4.511384 4.370803 4.168487
#> [3,] 4.485114 4.313869 4.375975
#> [4,] 4.255692 4.360584 4.485179
#> [5,] 4.015762 4.389781 4.187207
#> [6,] 4.038529 4.049635 4.042122
#> [7,] 4.143608 4.264234 4.508580
#> [8,] 5.763573 5.261314 5.399376
#> [9,] 4.844133 4.607299 4.750390
#> [10,] 4.576182 4.229197 3.831513
#> [11,] 4.276708 4.115328 4.048362
#> [12,] 4.152364 4.357664 4.692668
#> [13,] 4.376532 4.226277 4.528861
#> [14,] 4.647986 4.465693 4.318253
#> [15,] 4.190893 4.018978 4.304212
#> [16,] 4.378284 4.379562 4.308892
#> ACTGAGTGTTCCACGG-b02 AGCGGTCCATCCTTGC-b02 AGGCCACGTCCAGTAT-b02
#> [1,] 4.572222 4.115789 4.509863
#> [2,] 4.029630 4.015789 4.201821
#> [3,] 3.988889 4.307018 4.288316
#> [4,] 3.933333 4.500000 4.195751
#> [5,] 4.457407 3.977193 4.180577
#> [6,] 4.066667 3.810526 4.072838
#> [7,] 4.092593 4.108772 4.368741
#> [8,] 5.298148 5.280702 4.816388
#> [9,] 4.725926 4.666667 4.541730
#> [10,] 3.996296 3.956140 4.367223
#> [11,] 3.820370 4.422807 4.386950
#> [12,] 3.972222 4.484211 4.573596
#> [13,] 5.042593 4.224561 4.391502
#> [14,] 4.348148 4.622807 4.358118
#> [15,] 4.057407 4.361404 4.373293
#> [16,] 4.548148 4.010526 4.341426
#> ATCATGGCAGTTAACC-b02 ATCCGAACACAGGAGT-b02 ATCGAGTTCAGCTTAG-b02
#> [1,] 3.562376 3.852313 4.287755
#> [2,] 4.487129 4.514235 4.338776
#> [3,] 4.653465 4.245552 4.218367
#> [4,] 4.279208 4.400356 4.222449
#> [5,] 3.689109 4.428826 4.487755
#> [6,] 3.635644 4.403915 4.377551
#> [7,] 4.221782 4.448399 3.942857
#> [8,] 5.819802 5.208185 5.240816
#> [9,] 4.586139 4.373665 4.163265
#> [10,] 3.867327 4.448399 4.055102
#> [11,] 4.190099 4.549822 4.091837
#> [12,] 4.271287 4.124555 4.181633
#> [13,] 4.257426 4.377224 4.236735
#> [14,] 3.556436 4.361210 3.593878
#> [15,] 4.461386 4.177936 4.306122
#> [16,] 4.770297 4.419929 4.502041
#> ATCGAGTTCTGTGCAA-b02 ATGGGAGCATCGTCGG-b02 ATTATCCGTTGGGACA-b02
#> [1,] 4.034173 4.156648 4.486765
#> [2,] 4.571942 4.169399 4.469118
#> [3,] 4.156475 4.679417 4.377941
#> [4,] 4.505396 4.499089 4.419118
#> [5,] 4.197842 3.845173 4.286765
#> [6,] 3.874101 4.180328 4.155882
#> [7,] 4.287770 4.459016 4.183824
#> [8,] 5.634892 5.249545 5.279412
#> [9,] 4.811151 4.615665 4.636765
#> [10,] 4.267986 3.910747 4.232353
#> [11,] 4.476619 4.568306 4.597059
#> [12,] 4.311151 4.340619 4.597059
#> [13,] 3.953237 4.264117 4.202941
#> [14,] 4.365108 4.408015 4.286765
#> [15,] 4.368705 4.511840 4.026471
#> [16,] 4.458633 4.229508 4.651471
#> ATTCTACGTATCAGTC-b02 CAACTAGCATCCCACT-b02 CACAGGCGTCTCTCGT-b02
#> [1,] 4.073930 4.289377 4.521127
#> [2,] 4.548638 4.186813 4.220657
#> [3,] 4.348249 4.542125 4.477308
#> [4,] 4.406615 4.183150 4.308294
#> [5,] 4.155642 4.575092 4.275430
#> [6,] 4.760700 3.844322 4.025039
#> [7,] 4.336576 4.344322 3.912363
#> [8,] 4.959144 5.349817 5.413146
#> [9,] 4.972763 4.465201 4.568075
#> [10,] 4.005837 4.056777 3.962441
#> [11,] 3.821012 4.375458 4.248826
#> [12,] 4.640078 4.672161 4.395931
#> [13,] 3.982490 4.776557 4.677621
#> [14,] 4.634241 4.249084 3.935837
#> [15,] 4.307393 4.294872 4.061033
#> [16,] 4.797665 4.413919 4.006260
#> CACCACTAGTGACTCT-b02 CACTCCAAGCCTTGAT-b02 CAGTCCTCACAGACTT-b02
#> [1,] 4.257240 4.096439 4.310448
#> [2,] 4.427598 4.330861 4.401493
#> [3,] 4.422487 4.528190 4.656716
#> [4,] 4.325383 4.304154 4.207463
#> [5,] 4.035775 4.333828 4.305970
#> [6,] 4.250426 4.296736 4.183582
#> [7,] 4.412266 4.071217 3.701493
#> [8,] 5.495741 4.956973 5.282090
#> [9,] 4.342419 4.175074 4.556716
#> [10,] 4.253833 4.369436 4.379104
#> [11,] 4.596252 4.409496 4.205970
#> [12,] 4.536627 4.459941 4.450746
#> [13,] 4.383305 4.615727 4.411940
#> [14,] 4.306644 4.516320 4.371642
#> [15,] 4.672913 4.333828 3.988060
#> [16,] 3.908007 4.440653 4.444776
#> CATATGGAGATCACGG-b02 CATCCACTCCCTAACC-b02 CATCGAACACGTCAGC-b02
#> [1,] 4.250460 4.241379 4.674589
#> [2,] 4.228361 4.501567 4.007313
#> [3,] 4.296501 4.496865 3.650823
#> [4,] 4.703499 4.249216 4.310786
#> [5,] 4.101289 4.518809 4.288848
#> [6,] 3.795580 4.123824 4.234004
#> [7,] 4.187845 4.214734 4.405850
#> [8,] 5.303867 5.189655 4.815356
#> [9,] 4.331492 4.811912 4.778793
#> [10,] 4.025783 3.750784 4.208410
#> [11,] 4.429098 4.520376 4.016453
#> [12,] 4.458564 4.130094 4.193784
#> [13,] 4.020258 4.426332 4.608775
#> [14,] 4.206262 4.283699 3.857404
#> [15,] 4.370166 3.979624 4.093236
#> [16,] 3.895028 4.184953 4.312614
#> CATTATCTCCTTAATC-b02 CCACGGAAGAAACCAT-b02 CCAGCGATCGAATGCT-b02
#> [1,] 4.323529 4.546125 4.188103
#> [2,] 4.284314 4.300738 3.985531
#> [3,] 4.201961 4.372694 3.932476
#> [4,] 4.352941 4.230627 4.133441
#> [5,] 4.272549 4.267528 4.311897
#> [6,] 3.839216 3.955720 4.205788
#> [7,] 4.227451 4.199262 4.210611
#> [8,] 5.392157 5.016605 4.810289
#> [9,] 4.629412 4.498155 4.790997
#> [10,] 4.041176 4.051661 3.885852
#> [11,] 4.043137 4.365314 4.361736
#> [12,] 4.786275 4.734317 4.276527
#> [13,] 4.468627 4.239852 4.294212
#> [14,] 4.115686 4.134686 4.385852
#> [15,] 3.929412 3.833948 4.390675
#> [16,] 4.378431 4.031365 4.954984
#> CCATTCGGTGTGAAAT-b02 CCTACACGTCATGCCG-b02 CGAATGTCACTGAAGG-b02
#> [1,] 4.453094 4.373898 4.544753
#> [2,] 3.764471 4.266314 4.421296
#> [3,] 4.221557 4.268078 4.041667
#> [4,] 4.039920 4.301587 4.359568
#> [5,] 4.664671 4.271605 4.300926
#> [6,] 4.275449 3.820106 4.023148
#> [7,] 4.493014 3.970018 3.816358
#> [8,] 5.267465 5.033510 5.074074
#> [9,] 4.752495 4.045855 4.501543
#> [10,] 3.734531 3.876543 4.060185
#> [11,] 4.251497 4.460317 4.416667
#> [12,] 4.049900 3.823633 4.589506
#> [13,] 4.297405 4.146384 4.358025
#> [14,] 4.339321 4.248677 4.253086
#> [15,] 4.083832 3.823633 4.342593
#> [16,] 4.315369 3.948854 4.398148
#> CGAGAAGCATTGTGCA-b02 CGAGCACTCCCTAATT-b02 CGGACACCAAGGACTG-b02
#> [1,] 4.679675 4.222222 4.178782
#> [2,] 4.520325 4.339775 4.442043
#> [3,] 4.378862 4.491143 4.345776
#> [4,] 4.326829 4.280193 4.188605
#> [5,] 4.245528 4.291465 4.200393
#> [6,] 3.964228 4.049919 4.186640
#> [7,] 4.178862 4.041868 4.251473
#> [8,] 5.357724 4.933977 5.098232
#> [9,] 4.697561 4.462158 4.669941
#> [10,] 4.118699 4.314010 4.581532
#> [11,] 4.134959 4.394525 4.214145
#> [12,] 4.074797 4.380032 4.408644
#> [13,] 4.622764 4.370370 4.591356
#> [14,] 3.926829 4.392915 4.685658
#> [15,] 4.334959 4.312399 4.502947
#> [16,] 4.341463 4.563607 4.878193
#> CGTAGCGCACCCTATC-b02 CGTAGCGGTCATCGGC-b02 CGTCAGGGTCGAGTTT-b02
#> [1,] 4.644860 3.921606 4.020408
#> [2,] 4.191589 3.938815 4.579592
#> [3,] 4.529595 4.346080 4.355102
#> [4,] 4.219626 4.164436 4.265306
#> [5,] 3.945483 4.038241 4.300000
#> [6,] 3.772586 4.749522 4.197959
#> [7,] 4.503115 3.782027 4.206122
#> [8,] 5.495327 5.372849 5.251020
#> [9,] 4.562305 4.267686 4.444898
#> [10,] 4.160436 3.824092 3.889796
#> [11,] 4.471963 3.925430 4.283673
#> [12,] 4.347352 4.191205 4.051020
#> [13,] 4.247664 4.504780 4.091837
#> [14,] 4.029595 4.931166 4.124490
#> [15,] 4.727414 4.250478 4.169388
#> [16,] 4.214953 5.233270 4.426531
#> CTCACACCAACACCTA-b02 CTCACACCACCAGGTC-b02 CTCATTACACATGTGT-b02
#> [1,] 4.396899 4.437262 4.247078
#> [2,] 4.406202 4.541825 4.352254
#> [3,] 3.973643 4.349810 4.489149
#> [4,] 4.337984 4.488593 4.666110
#> [5,] 4.382946 4.340304 3.864775
#> [6,] 4.693023 4.482890 3.954925
#> [7,] 4.246512 4.077947 4.083472
#> [8,] 5.255814 5.686312 5.257095
#> [9,] 4.493023 4.119772 5.125209
#> [10,] 4.189147 4.030418 4.325543
#> [11,] 4.486822 4.034221 4.031720
#> [12,] 4.539535 4.389734 4.220367
#> [13,] 4.351938 4.558935 3.909850
#> [14,] 4.525581 4.258555 4.245409
#> [15,] 4.496124 4.539924 4.176962
#> [16,] 4.286822 4.317490 4.305509
#> CTCGAGGTCAGATAAG-b02 CTGGTCTGTATCGCAT-b02 CTTCTCTCATCCTTGC-b02
#> [1,] 4.424332 4.394775 3.888013
#> [2,] 3.991098 4.526851 4.285489
#> [3,] 4.783383 4.177068 3.976341
#> [4,] 4.425816 4.506531 3.763407
#> [5,] 4.316024 4.076923 4.231861
#> [6,] 4.041543 4.416546 4.424290
#> [7,] 3.893175 4.181422 3.731861
#> [8,] 6.041543 5.538462 5.056782
#> [9,] 4.381306 4.923077 4.582019
#> [10,] 3.912463 4.415094 4.111987
#> [11,] 4.249258 4.599419 3.903785
#> [12,] 4.360534 4.377358 4.343849
#> [13,] 4.028190 4.114659 4.061514
#> [14,] 4.289318 4.156749 4.446372
#> [15,] 4.701780 4.442671 4.255521
#> [16,] 4.286350 4.454282 4.828076
#> GACACGCCAGCTTCGG-b02 GATTCAGGTTCACCTC-b02 GCATGATTCAGTCCCT-b02
#> [1,] 4.580398 4.366438 4.486
#> [2,] 4.266462 4.474315 4.272
#> [3,] 4.133231 4.467466 3.884
#> [4,] 4.214395 4.727740 4.946
#> [5,] 4.468606 4.510274 4.426
#> [6,] 4.119449 4.510274 4.296
#> [7,] 4.137825 4.231164 4.132
#> [8,] 5.535988 5.311644 5.398
#> [9,] 4.782542 4.071918 4.186
#> [10,] 4.228178 3.905822 4.340
#> [11,] 4.454824 4.503425 4.094
#> [12,] 4.666156 4.183219 4.576
#> [13,] 4.589587 4.638699 4.110
#> [14,] 4.315467 3.919521 4.624
#> [15,] 4.300153 4.400685 4.400
#> [16,] 4.372129 4.472603 4.052
#> GCATGATTCAGTGTTG-b02 GCATGTATCGTTTATC-b02 GCGCAACAGTTATCGC-b02
#> [1,] 4.208202 4.312057 4.510569
#> [2,] 4.236593 4.515957 4.536585
#> [3,] 4.525237 4.448582 4.256911
#> [4,] 4.406940 4.535461 4.190244
#> [5,] 4.548896 4.225177 3.894309
#> [6,] 4.015773 4.129433 4.211382
#> [7,] 4.329653 4.040780 4.008130
#> [8,] 5.149842 5.117021 5.196748
#> [9,] 4.596215 4.535461 4.479675
#> [10,] 4.219243 4.482270 4.069919
#> [11,] 4.244479 4.237589 4.533333
#> [12,] 4.493691 4.487589 4.679675
#> [13,] 4.247634 4.462766 4.466667
#> [14,] 4.443218 4.173759 4.334959
#> [15,] 4.239748 4.184397 4.582114
#> [16,] 4.394322 4.161348 4.421138
#> GCGCAGTTCGCCAGCA-b02 GCTGCGATCTTCTGGC-b02 GCTGGGTAGCAATCTC-b02
#> [1,] 4.373866 4.807692 4.727723
#> [2,] 4.413793 4.794314 4.209571
#> [3,] 4.381125 4.528428 4.519802
#> [4,] 4.123412 4.202341 4.191419
#> [5,] 4.185118 4.489967 4.420792
#> [6,] 4.049002 4.680602 4.181518
#> [7,] 4.103448 4.476589 4.084158
#> [8,] 5.488203 4.821070 5.495050
#> [9,] 4.700544 3.946488 4.580858
#> [10,] 4.156080 4.615385 4.301980
#> [11,] 4.479129 4.185619 4.044554
#> [12,] 4.435572 4.198997 4.496700
#> [13,] 4.444646 4.585284 4.729373
#> [14,] 4.186933 4.478261 4.160066
#> [15,] 4.165154 4.143813 4.150165
#> [16,] 4.368421 4.279264 3.805281
#> GCTGGGTCATACGCCG-b02 GGACAAGGTGTTGGGA-b02 GGACAGAAGAAGGTTT-b02
#> [1,] 4.469605 4.394834 4.828814
#> [2,] 4.376900 4.304428 4.293220
#> [3,] 4.193009 4.509225 4.355932
#> [4,] 4.386018 4.103321 4.261017
#> [5,] 4.001520 4.047970 4.561017
#> [6,] 4.296353 4.083026 4.435593
#> [7,] 3.813070 4.197417 4.261017
#> [8,] 5.300912 5.590406 5.205085
#> [9,] 5.109422 4.634686 4.842373
#> [10,] 4.623100 3.610701 3.877966
#> [11,] 3.998480 4.186347 4.193220
#> [12,] 4.525836 4.540590 4.450847
#> [13,] 4.422492 4.300738 4.613559
#> [14,] 4.744681 4.234317 4.006780
#> [15,] 4.282675 4.226937 4.100000
#> [16,] 4.455927 4.328413 4.293220
#> GGCAATTGTGTAATGA-b02 GGCGTGTCATCGGGTC-b02 GGGAATGCACAAGTAA-b02
#> [1,] 4.014815 4.279773 4.110754
#> [2,] 4.600000 4.272212 4.462279
#> [3,] 4.442593 4.408318 4.471910
#> [4,] 4.216667 4.151229 4.616372
#> [5,] 4.079630 4.298677 4.404494
#> [6,] 3.842593 3.724008 4.001605
#> [7,] 4.253704 4.359168 4.165329
#> [8,] 5.487037 5.478261 5.263242
#> [9,] 4.253704 4.559546 4.608347
#> [10,] 3.975926 4.228733 4.365971
#> [11,] 4.287037 3.924386 4.102729
#> [12,] 4.257407 3.973535 4.279294
#> [13,] 4.020370 4.425331 4.406100
#> [14,] 4.107407 3.739130 4.321027
#> [15,] 4.453704 4.228733 4.174960
#> [16,] 4.342593 4.034026 4.014446
#> GGGCACTAGCCTTGAT-b02 GTACTTTGTTACTGAC-b02 GTAGGCCCAGATCGGA-b02
#> [1,] 4.366136 4.327928 4.272177
#> [2,] 4.885673 4.450450 4.201613
#> [3,] 4.610709 4.704505 4.457661
#> [4,] 3.985528 4.425225 4.100806
#> [5,] 4.191027 4.452252 4.506048
#> [6,] 4.622287 4.027027 4.199597
#> [7,] 4.120116 4.028829 4.058468
#> [8,] 4.752533 5.245045 5.304435
#> [9,] 4.162084 4.279279 4.532258
#> [10,] 3.743849 3.909910 4.421371
#> [11,] 4.570188 4.172973 4.278226
#> [12,] 4.897250 4.369369 4.731855
#> [13,] 4.008683 4.452252 4.344758
#> [14,] 4.124457 3.962162 4.260081
#> [15,] 4.214182 4.309910 4.175403
#> [16,] 4.222865 4.250450 4.546371
#> GTAGTCACACTCAGGC-b02 GTCACGGAGAGGTAGA-b02 GTGCATACAACTGCGC-b02
#> [1,] 4.092593 4.186944 4.392063
#> [2,] 3.927609 4.142433 4.371429
#> [3,] 4.506734 4.277448 4.290476
#> [4,] 4.404040 4.437685 4.395238
#> [5,] 4.569024 4.038576 4.417460
#> [6,] 4.393939 4.247774 3.973016
#> [7,] 4.350168 4.385757 4.115873
#> [8,] 4.978114 5.143917 5.226984
#> [9,] 4.469697 4.761128 4.282540
#> [10,] 3.989899 4.357567 4.000000
#> [11,] 4.414141 4.863501 4.304762
#> [12,] 4.575758 4.532641 4.584127
#> [13,] 4.634680 4.075668 4.273016
#> [14,] 4.466330 4.396142 4.430159
#> [15,] 4.239057 4.620178 4.352381
#> [16,] 4.617845 4.140950 4.353968
#> TACCTATAGTTAGGTA-b02 TAGACCAAGATCTGAA-b02 TAGAGCTAGTACGCGA-b02
#> [1,] 4.320755 4.122278 4.374443
#> [2,] 4.501887 4.296482 4.499257
#> [3,] 4.607547 4.517588 4.145617
#> [4,] 4.537736 4.358459 4.356612
#> [5,] 4.218868 4.154104 4.166419
#> [6,] 3.947170 3.862647 3.979198
#> [7,] 4.228302 4.142379 4.427935
#> [8,] 5.216981 5.308208 5.343239
#> [9,] 4.288679 4.562814 4.451709
#> [10,] 4.094340 4.154104 3.858841
#> [11,] 4.266038 4.018425 4.399703
#> [12,] 4.388679 4.291457 4.381872
#> [13,] 4.496226 4.115578 4.285290
#> [14,] 4.213208 4.120603 4.115899
#> [15,] 4.164151 4.644891 3.997028
#> [16,] 3.790566 4.162479 4.424963
#> TATTACCGTCCAGTTA-b02 TCAGATGAGATGGGTC-b02 TCAGATGGTAGAGCTG-b02
#> [1,] 4.006873 4.431034 4.256228
#> [2,] 4.041237 3.896552 4.284698
#> [3,] 4.443299 4.145768 4.528470
#> [4,] 4.345361 4.188088 4.008897
#> [5,] 3.958763 4.523511 4.227758
#> [6,] 4.020619 4.252351 3.813167
#> [7,] 4.469072 3.968652 3.955516
#> [8,] 5.376289 5.324451 5.587189
#> [9,] 4.462199 4.699060 4.991103
#> [10,] 4.238832 4.120690 3.857651
#> [11,] 3.902062 4.147335 4.177936
#> [12,] 4.323024 4.335423 4.562278
#> [13,] 4.496564 4.434169 4.688612
#> [14,] 3.912371 4.302508 4.407473
#> [15,] 4.225086 4.514107 4.480427
#> [16,] 4.347079 4.374608 4.665480
#> TCCCGATTCGCCGTGA-b02 TCGTACCTCAACGCTA-b02 TGATTTCCAGTCTTCC-b02
#> [1,] 4.066190 4.408088 4.286689
#> [2,] 4.454383 4.314338 4.595563
#> [3,] 4.205725 4.566176 4.477816
#> [4,] 4.186047 4.321691 4.259386
#> [5,] 4.438283 4.095588 4.274744
#> [6,] 3.937388 4.183824 4.254266
#> [7,] 4.130590 4.325368 3.979522
#> [8,] 5.196780 4.937500 5.186007
#> [9,] 4.894454 4.042279 4.766212
#> [10,] 3.942755 4.123162 4.145051
#> [11,] 4.558140 4.238971 4.273038
#> [12,] 4.386404 4.500000 4.530717
#> [13,] 4.445438 4.284926 4.308874
#> [14,] 4.586762 4.240809 4.259386
#> [15,] 4.252236 4.051471 4.146758
#> [16,] 4.601073 3.840074 4.624573
#> TGCGCAGCAGGATTGG-b02 TGCGCAGTCCCTGACT-b02 TGCGGGTAGTACTTGC-b02
#> [1,] 4.269406 4.151402 4.391144
#> [2,] 4.223744 4.463551 4.387454
#> [3,] 4.261796 4.205607 4.514760
#> [4,] 4.792998 4.388785 4.079336
#> [5,] 4.447489 4.186916 4.431734
#> [6,] 4.243531 3.829907 4.121771
#> [7,] 4.350076 3.790654 4.062731
#> [8,] 5.217656 4.958879 5.175277
#> [9,] 5.007610 4.859813 4.381919
#> [10,] 4.333333 4.885981 4.164207
#> [11,] 4.634703 4.418692 4.280443
#> [12,] 4.430746 4.315888 4.411439
#> [13,] 4.159817 4.635514 4.369004
#> [14,] 4.251142 4.495327 3.669742
#> [15,] 4.272451 4.938318 4.130996
#> [16,] 4.407915 4.059813 4.136531
#> TTTGTCAAGTACACCT-b02
#> [1,] 4.434381
#> [2,] 4.436229
#> [3,] 4.451017
#> [4,] 4.105360
#> [5,] 4.133087
#> [6,] 4.327172
#> [7,] 4.475046
#> [8,] 5.743068
#> [9,] 4.438078
#> [10,] 4.138632
#> [11,] 4.304991
#> [12,] 4.373383
#> [13,] 4.120148
#> [14,] 4.179298
#> [15,] 4.341959
#> [16,] 4.011091
#> [ reached getOption("max.print") -- omitted 84 rows ]